SAKURAI Susumu 桜井進

… Alternative Names

桜井進サクライススム

SAKURAI S. 桜井進

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Researcher Number	20056542
External Links
Affiliation (Current)	2025: 公益財団法人河野臨牀医学研究所, その他部局等, 研究員(移行)
Affiliation (based on the past Project Information) *help	2004: Kohno Clinical Medicine Research Institute, Chief Researcher, 室長 2002 – 2003: 河野臨床医学研究所, 主任研究員 1999: Kohno Clinical Medicine Research Institute, Chief Reseacher, 主任研究員 1997 – 1998: 河野臨床検医学研究室, 主任研究員 1991 – 1994: Jikei Univ. Molecular Lab. Professor, 医学部, 教授 1989 – 1990: 東京慈恵会医科大学, 遺伝子工学, 教授 1988 – 1989: 東京慈恵会医科大学, 医学部, 教授
Review Section/Research Field	Except Principal Investigator Laboratory medicine / Pediatrics
Keywords	Except Principal Investigator Fibronectin / Staphylococcal exfoliative toxin / ブドウ球菌性表皮剥脱素 / plakoglobin / β-catenin / ETA, ETB / Plakoglobin / Immune response gene / Cellular immunity / 免疫応答遺伝子 … More / 液性免疫 / 細胞性免疫 / 伝染性膿痂疹 / ETA / HLA-DR / Humoral immunity / Staphylococcal infection / gene cloning / Gene cloning / desmocalmin / desmoyokin / plectin / desmocollin 1 / beta-catenin / ブドウ球菌性表皮剥奪素 / ganglioside / desmosomal cadherin / staphylococcal exfoliative toxin / 黄色ブドウ球菌性表皮剥脱毒素 / glucose intolerance / urinary albumin / Catenin / Staphylococcal Exfoliative Toxin / 黄色ブドウ球菌性熱傷様皮膚症候群 / プラコグロビン / カテニン / フィブロネクチン / 黄色ブドウ球菌性表皮剥脱素 / Staphylococcal impetigo / HLA / PHA / 表皮剥脱素 / PCR法 / Exfoliative Toxin / ブドウ球菌膿痂疹患者 / ブドウ球菌性熱傷様皮膚症候群 / NGF receptor / Signal Transduction / Psychosine / Nimann-Pick Disease / Krabbe Disease / レトロウイルスベクタ- / Niemann-Pichマウス / 動物モデル / リポゾ-ム療法 / マンノ-ス含有オリゴ糖 / Blood Brain barrier / スフィンゴミエリナ-ゼ / twitcherマウス / NiemannーPick病マウス / NGFRカスケ-ド / NGF / NGFRcDNA / golgiーlysosomal complex / コレステロ-ル / NiemannーPickマウス / サイコシン / オリゴデンドログリア細胞 / Krabbe病 Less

Analysis of susceptibility to staphylococcal exfoliative toxin and gene expression of plakoglobin in a newborn and an eight-day-old mouse
- Principal Investigator
  
  HOSHINA Sadayori, 町田勝彦
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDICINE
The analytical study of dispreposition to Stapylococcal Schalded Skin syndrome.
- Principal Investigator
  
  MACHIDA Katsuhiko
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDICINE
Analysis of the relation between immune response to staphylococcal exfoliative toxin A and susceptibility to disease in patients with staphylococcal scalded skin syndrome.
- Principal Investigator
  
  MACHIDA Katsuhiko
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  TOKYO JIKEI UNIVERSITY
Cellular engineering for treatment of animal model for inherited brain disorder
- Principal Investigator
  
  MAEKAWA K.
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Jikei University School of Medicine
Analysis of human immune response genes to microbial toxin.
- Principal Investigator
  
  MACHIDA Katsuhiko
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  TOKYO JIKEI UNIVERSITY

All 2004 2003 2002

All Journal Article

[Journal Article] A novel positive regulatory element for exfoliative toxin A gene expression in Staphylococcus aureus.2004
- Author(s)
  Susumu Sakurai, Hitoshi Suzuki, Yukio Yoshizawa, Toshiaki Hata, Ritsuko Nakayama, Katsuhiko Machida, Shogo Masuda, Takashi Tsukiyama
- Journal Title
  
  Microbiology Vol.150
  
  Pages: 945-952
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] A novel positive regulatory element for exfoliative toxin A gene expression in Staphylococcus aureus.2004
- Author(s)
  Susumu Sakurai, Hitoshi Suzuki, etc.
- Journal Title
  
  Microbiology 150
  
  Pages: 945-952
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Synthesis of exfoliative toxin A is positively regulated at transcriptional level by ETA^<exp> in Staphylococcus aureus.2004
- Author(s)
  Susumu Sakurai, Katsuhiko Machida
- Journal Title
  
  Archives of Kohno Clinical Medicine Research Institute 19
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] A novel positive regulatory element for exfoliative toxin A gene expression in Staphylococcus aureus.2004
- Author(s)
  Susumu Sakurai, Hitosbi Suzuki, etc.
- Journal Title
  
  Microbiology 150
  
  Pages: 945-952
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Plakoglobin, an intracellular plaque protein of the desmosome and the cleavage activity of staphylococcal exfoliative toxin at desmosomes.2004
- Author(s)
  Susumu Sakurai, Keiko Fukushima, Midori Kohno, Sadayori Hoshina
- Journal Title
  
  Bulletin of Kohno Clinical Medicine Research Institute (in Japanese) Vol.54
  
  Pages: 3-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Synthesis of exfoliative toxin A is positively regulated at transcriptional level by ETA^<exp> in Staphylococcus aureus.2004
- Author(s)
  Susumu Sakurai, Katsuhiko Machida
- Journal Title
  
  Archives of Kohno Clinical Medicine Research Institute Vol.19
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Ritter病、ブドウ球菌性膿痂疹の病原因子である黄色ブドウ球菌表皮剥脱毒素が切断する細胞接着因子2004
- Author(s)
  桜井進, 福島慶子, 河野緑, 保科定頼
- Journal Title
  
  河医研研究年報 54
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Expression of wnt signaling molecules in the synovial membranes of rabbit ankle joints injected with Enterococcus faecalis cell fractions.2004
- Author(s)
  Susumu Sakurai, Takeshi Hayashi, Shinichi Iwasaki, Toshihiko Kohno, Minoru Kohno
- Journal Title
  
  Mod.Rheumatol. Vol.13
  
  Pages: 35-43
- NAID
  10015486629
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Regulation of α-toxin, staphylokinase and staphylococcal exfoliative toxin B gene expression by ETA^<exp>, which regulates expression of staphylococcal exfoliative toxin A gene in Staphylococcus aureus.2004
- Author(s)
  Keiko Fukushima, Susumu Sakurai
- Journal Title
  
  Archives of Kohno Clinical Medicine Research Institute Vol.20
  
  Pages: 1-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Cloning and sequence determination of a gene coding for the substrate of an exfoliative toxin from Staphylococcus aureus.2003
- Author(s)
  Katsuhiko Machida, Susumu Sakurai, Midori Kohno, Sadayori Hoshina, Minoru Kohno
- Journal Title
  
  Archives of Kohno Clinical Medicine Research Institute Vol.18
  
  Pages: 9-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Cloning and sequence determination of a gene coding for the substrate of an exfoliative toxin from Staphylococcus aureus.2003
- Author(s)
  Katsuhiko Machida, Susumu Sakurai, etc.
- Journal Title
  
  Archives of Kohno Clinical Medicine Research Institute 18
  
  Pages: 9-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Expression of wnt signaling molecules in the synovial membranes of rabbit ankle joints injected with Enterococcus faecalis cell fractions.2003
- Author(s)
  Susumu Sakurai, Takeshi Hayashi, etc.
- Journal Title
  
  Mod.Rheumatol 13
  
  Pages: 35-43
- NAID
  10015486629
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Expression of wnt signaling molecules in the synovial membranes of rabbit ankle joints injected with Enterococcus faecalis cell fractions.2003
- Author(s)
  Susumu Sakurai, Takeshi Hayashi, etc.
- Journal Title
  
  Mod. Rheumatol 13
  
  Pages: 35-43
- NAID
  10015486629
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Induction of chronic arthritis by staphylococcal exfoliative toxin A in DBA/1J mice primed with bovine type II collagen.2002
- Author(s)
  Susumu Sakurai, Taisuke Yamazaki, Naruto Matsuo, Minoru Kohno
- Journal Title
  
  Archives of Kohno Clinical Medicine Research Institute Vol.17
  
  Pages: 9-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370798
[Journal Article] Induction of chronic arthritis by staphylococcal exfoliative toxin A in DBA/1J mice primed with bovine type II collagen.2002
- Author(s)
  Susumu Sakurai, Taisuke Yamazaki, etc.
- Journal Title
  
  Archives of Kohno Clinical Medicine Research Institute 17
  
  Pages: 9-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370798

1. MACHIDA Katsuhiko (70056886)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. HOSHINA Sadayori (30119846)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. KAMIDE Ryouichi (40119780)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. KOHNO Midori (00225385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. MAEKAWA K. (80056613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TOKORO T. (40112841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ITO F. (10057010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ETO Y. (50056909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KITAHARA Shintaro (20186258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 奈良隆寛 (80180537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAKURAI Susumu 桜井 進

桜井 進 サクライ ススム

SAKURAI S. 桜井 進

Research Projects

Research Products

Co-Researchers

Analysis of susceptibility to staphylococcal exfoliative toxin and gene expression of plakoglobin in a newborn and an eight-day-old mouse

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analytical study of dispreposition to Stapylococcal Schalded Skin syndrome.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the relation between immune response to staphylococcal exfoliative toxin A and susceptibility to disease in patients with staphylococcal scalded skin syndrome.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cellular engineering for treatment of animal model for inherited brain disorder

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of human immune response genes to microbial toxin.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A novel positive regulatory element for exfoliative toxin A gene expression in Staphylococcus aureus.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] A novel positive regulatory element for exfoliative toxin A gene expression in Staphylococcus aureus.2004

Author(s)

Journal Title

Data Source

[Journal Article] Synthesis of exfoliative toxin A is positively regulated at transcriptional level by ETA^<exp> in Staphylococcus aureus.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] A novel positive regulatory element for exfoliative toxin A gene expression in Staphylococcus aureus.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Plakoglobin, an intracellular plaque protein of the desmosome and the cleavage activity of staphylococcal exfoliative toxin at desmosomes.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Synthesis of exfoliative toxin A is positively regulated at transcriptional level by ETA^<exp> in Staphylococcus aureus.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Ritter病、ブドウ球菌性膿痂疹の病原因子である黄色ブドウ球菌表皮剥脱毒素が切断する細胞接着因子2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Expression of wnt signaling molecules in the synovial membranes of rabbit ankle joints injected with Enterococcus faecalis cell fractions.2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Regulation of α-toxin, staphylokinase and staphylococcal exfoliative toxin B gene expression by ETA^<exp>, which regulates expression of staphylococcal exfoliative toxin A gene in Staphylococcus aureus.2004

Author(s)

Journal Title

Description

SAKURAI Susumu 桜井進

桜井進サクライススム

SAKURAI S. 桜井進