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TOKORO Toshiharu
所 敏治
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Alternative Names
TOKORO T. 所 敏治
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Researcher Number
40112841
Affiliation (based on the past Project Information)
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1999 – 2000: 東京慈恵会医科大学, 医学部, 講師
1991 – 1994: Jikei Univ. Pediatrics assistant prof., 医学部, 講師
1993: 東京慈恵会医科大学, 医学部・小児科, 講師
1993: lecturer, 小児科, 講師
1990: 東京慈恵会医科大学, 小児科, 講師
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1990: Jikei Univ. Prof. asst., 小児科学, 講師
1989: 東京慈恵会医科大学, 医学部小児科, 助手
1988 – 1989: 東京慈恵会医科大学, 小児科, 助手
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Review Section/Research Field
Principal Investigator
Pediatrics
Except Principal Investigator
Pediatrics
Keywords
Principal Investigator
スフィンゴミエリン / ニーマンピック病 / SPMマウス / CSDマウス / エステル化障害 / 遺伝学的類似性 / スフィンゴシェリン / NemannーPick病 / コレステロ-ル / コレステロ-ルエステル
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/ 細胞内転送機構 / 胎児肝細胞移植 / Niemann-Pick Disease / Cholesterol esterification / Genetic homogenity / Cross hybridization / SPM mouse / CDS mouse / ヒトニーマンピック病タイプC / 胎児遺伝子治療 / レトロウイルスベクター / コレステロールのエステル化障害 / レトロウィルスベクター / Lacz遺伝子 / 胎児肝臓 / アデノウィルスベクター / 脳血液関門 / Ca代謝 / コレステロールエステル / Niemann-Pick disease type C / fetus gene therapy / deficient cholesterol esterification / retroviral vector / Nieman-Pick病type C / β-galactosidase / レトロウイルス / サイトカイン / アデノウイルスベクター / Niemann-Pick病type C / Nieman-Pick病typeC / Neural progenitor / Niemann-Pick Disease TypeC / Adenovirus Vector / Cytkine / クラベ病 / サイコシン / Twitcherマウス / ニ-マンピック病 / ライソゾ-ム病 / 神経培養 / E-64 / (1)krabbe病 / (2)サイコシン / (3)脱髄 / (4)培養オリゴデンドロサイト / (5)Twitcherマウス / Krabbe's disease / Psychosine / Twitcher mouse / Niemann-Pick mouse / Lysosomal disorder
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Except Principal Investigator
異染性脳白質変性症 / 遺伝子治療 / 遺伝子解析 / MLD / サイコシン / オリゴデンドログリア細胞 / Gaucher病 / レトロウイルスベクター / ガラクトシ-ルーβーガラクトシダ-ゼ / 中枢神経培養細胞 / スフィンゴシングルコサイコシン / ガラクトサミン / GLD培養細胞 / アデノウイルス / レトロウイルス / オリゴデンドロサイト / サルファターゼ / Krabbe病 / NiemannーPickマウス / コレステロ-ル / golgiーlysosomal complex / NGFRcDNA / NGF / NGFRカスケ-ド / NiemannーPick病マウス / twitcherマウス / スフィンゴミエリナ-ゼ / Blood Brain barrier / マンノ-ス含有オリゴ糖 / リポゾ-ム療法 / 動物モデル / Niemann-Pichマウス / レトロウイルスベクタ- / Krabbe Disease / Nimann-Pick Disease / Psychosine / Signal Transduction / NGF receptor / マルチプルサルファタ-ゼ欠損症 / アリルサルファタ-ゼA / アルチプルサルファタ-ゼ欠損症 / リン酸化障害 / ライソゾ-ム酵素 / multiple sulfatase deficiency / 脳血液関門 / 酵素補充法 / cerebrosideーβーgalactoside / ^ース / 酵素抗体染色 / リボゾ-ム / グリア細胞 / cerebrosideβ-galactosidase / マンノ-ス / リポゾ-ム / 脳障害 / 酵素補充療法 / α_2ーマクログロブリン / 培養神経細胞 / αーマンノ-ス含有リポゾ-ム / liposome / blood brain barrier / neuronal cell / mannnose terminal / Glucocerebrosidase / 遺伝子変異 / Nerve Growth Factor / 異染性白質変性症 / クラベ病 / 脱髄 / 呼吸鎖リン酸化反応 / ミエリン形成異常症 / ゴーシェ病 / 制限酵素 / PCR法 / スプライスアクセプターサイト / Gaucher disease / Metachromatic / Krabbe's disease / genotype / gene therapy / demyelination / 先天性ミエリン形成異常症 / matachromatic leukodystrophy(MLD) / RT-PCR法 / 遺伝子変異解析 / ArylsulfataseA / PCR-SSCP法 / PMD / PCR / ASO / SSCP / アデノウイルスベクター / アリルスルファターゼA遺伝子 / 遺伝型と臨床型 / Gaucher Disease / RT-PCR / Arylsulfatase A / PCR-SSCP
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Research Projects
(
11
results)
Co-Researchers
(
19
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Treatment for congenital metabolic disorder with brain dysfunction.
Principal Investigator
Principal Investigator
TOKORO Toshiharu
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pediatrics
Research Institution
The Jikei University School of Medicine
リピドーシス動物モデルを用いての中枢神経障害の遺伝子治療
Principal Investigator
衛藤 義勝
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pediatrics
Research Institution
Jikei University School of Medicine
Molecular Analysis and Gene Therapy in Inherited dysmyelinating disorder
Principal Investigator
MAEKAWA Kihei
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Pediatrics
Research Institution
The Jikei University School of Medicine
Gene therapy for inherited neurodegenerative disease using fetal bone marrows stem cell transplantation.
Principal Investigator
Principal Investigator
TOKORO Toshiharu
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pediatrics
Research Institution
The Jikei Univ.School of Medicine
Studies of genetic analysis and gene therapy for myelin-associated disorders.
Principal Investigator
MAEKAWA Kihei
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pediatrics
Research Institution
The Jikei University School of Medicine
Genetic analysis of Niemann-Pick model mouse.
Principal Investigator
Principal Investigator
TOKORO Toshoharu
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pediatrics
Research Institution
Jikei Univ.School of Medicine
リピド-シスマウス神経細胞に於けるガングリオシド代謝とその機能異常の解明
Principal Investigator
ETO Y.
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Jikei University School of Medicine
Cellular engineering for treatment of animal model for inherited brain disorder
Principal Investigator
MAEKAWA K.
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Pediatrics
Research Institution
Tokyo Jikei University School of Medicine
Pathogenesis of Multiple Sulfatase Deficiency
Principal Investigator
ETO Yoshikatsu
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pediatrics
Research Institution
Tokyo Jikei University School of Medicine
Modified enzyme which target to neuronal cells to cross blood brain barrier
Principal Investigator
ETO Yoshikatsu
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Pediatrics
Research Institution
Tokyo Jikei University School of Medicine
The Pathogenesis of Demyelination in Krabbe's disease and it's therapy
Principal Investigator
Principal Investigator
TOKORO Toshiharu
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pediatrics
Research Institution
The Jikei University School of Medicine, Department of Pediatrics
# of Projects (Dsc)
# of Projects (Asc)
1.
ETO Y.
(50056909)
# of Collaborated Projects:
11 results
# of Collaborated Products:
0 results
2.
IDA Hiroyuki
(90167255)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
3.
ITO F.
(10057010)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
4.
OHASHI T.
(60160595)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
5.
UMEZAWA Fusayo
(50185063)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
MAEKAWA K.
(80056613)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
長谷川 頼康
(60256435)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
SASAKI Nobuhiko
(50170684)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
TATSUSHIMA H.
(70190460)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
津田 隆
(50188554)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
奈良 隆寛
(80180537)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
SAKURAI S.
(20056542)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
五味渕 一三
(50205621)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
TOYODA Shigeru
(90110931)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
KUSANO Kaoru
(80205070)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
ONO Tsuneya
(60147288)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
大野 京子
(10301524)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
小林 博司
(90266619)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
SEKIGUCHI Shigeru
(90119818)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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