TOKORO T. 所敏治

Researcher Number	40112841
Affiliation *help	2016 : 聖徳大学, 児童学部, 教授 1999 – 2000 : 東京慈恵会医科大学, 医学部, 講師 1991 – 1994 : Jikei Univ. Pediatrics assistant prof., 医学部, 講師 1993 : 東京慈恵会医科大学, 医学部・小児科, 講師 1993 : lecturer, 小児科, 講師 … More
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics
Keywords	Principal Investigator E-64 / レトロウイルスベクター / Cross hybridization / Niemann-Pick Disease TypeC / 胎児肝臓 / retroviral vector / アデノウイルスベクター / ヒトニーマンピック病タイプC / コレステロ-ル / サイトカイン … More Except Principal Investigator 遺伝子解析 / 異染性脳白質変性症 / 遺伝子治療 / MLD / サイコシン / Gaucher病 / オリゴデンドログリア細胞 / レトロウイルスベクター / スプライスアクセプターサイト / 酵素補充療法 / Nimann-Pick Disease / リポゾ-ム療法 / オリゴデンドロサイト / アデノウイルスベクター / multiple sulfatase deficiency / 脳血液関門 / NGFRカスケ-ド / RT-PCR / グリア細胞 / α_2ーマクログロブリン / スフィンゴシングルコサイコシン / matachromatic leukodystrophy(MLD) / RT-PCR法 / リン酸化障害 / cerebrosideーβーgalactoside / 酵素補充法 / SSCP / mannnose terminal / マンノ-ス含有オリゴ糖 / GLD培養細胞 / アルチプルサルファタ-ゼ欠損症 / ArylsulfataseA / NGFRcDNA / NGF / PCR / 制限酵素 / 中枢神経培養細胞 / 脱髄 / 動物モデル / golgiーlysosomal complex / ガラクトサミン / ゴーシェ病 / Signal Transduction / 異染性白質変性症 / PCR法 / クラベ病 / Gaucher Disease / 脳障害 / スフィンゴミエリナ-ゼ / ライソゾ-ム酵素 / マルチプルサルファタ-ゼ欠損症 / Niemann-Pichマウス / リポゾ-ム / NiemannーPick病マウス / cerebrosideβ-galactosidase / Nerve Growth Factor / アデノウイルス / PCR-SSCP法 / ^ース / リボゾ-ム / Krabbe's disease / 遺伝型と臨床型 / 培養神経細胞 / genotype / PMD / ASO / Blood Brain barrier / neuronal cell / αーマンノ-ス含有リポゾ-ム / 遺伝子変異 / Krabbe Disease / Krabbe病 / レトロウイルスベクタ- / Metachromatic / ミエリン形成異常症 / demyelination / 呼吸鎖リン酸化反応 / アリルサルファタ-ゼA / blood brain barrier / 酵素抗体染色 / gene therapy / twitcherマウス / コレステロ-ル / 先天性ミエリン形成異常症 / ガラクトシ-ルーβーガラクトシダ-ゼ / Arylsulfatase A / PCR-SSCP / 遺伝子変異解析 / レトロウイルス / NGF receptor / liposome / NiemannーPickマウス / サルファターゼ / Gaucher disease / Glucocerebrosidase / Psychosine / マンノ-ス / アリルスルファターゼA遺伝子 Less

Research Projects
(11results)
Co-Researchers
(19People)

Treatment for congenital metabolic disorder with brain dysfunction.Principal Investigator
- Principal Investigator
  
  TOKORO Toshiharu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The Jikei University School of Medicine
リピドーシス動物モデルを用いての中枢神経障害の遺伝子治療
- Principal Investigator
  
  衛藤義勝
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jikei University School of Medicine
Molecular Analysis and Gene Therapy in Inherited dysmyelinating disorder
- Principal Investigator
  
  MAEKAWA Kihei
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  The Jikei University School of Medicine
Gene therapy for inherited neurodegenerative disease using fetal bone marrows stem cell transplantation.Principal Investigator
- Principal Investigator
  
  TOKORO Toshiharu
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The Jikei Univ.School of Medicine
Studies of genetic analysis and gene therapy for myelin-associated disorders.
- Principal Investigator
  
  MAEKAWA Kihei
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  The Jikei University School of Medicine
Genetic analysis of Niemann-Pick model mouse.Principal Investigator
- Principal Investigator
  
  TOKORO Toshoharu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jikei Univ.School of Medicine
リピド-シスマウス神経細胞に於けるガングリオシド代謝とその機能異常の解明
- Principal Investigator
  
  ETO Y.
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jikei University School of Medicine
Cellular engineering for treatment of animal model for inherited brain disorder
- Principal Investigator
  
  MAEKAWA K.
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Jikei University School of Medicine
Pathogenesis of Multiple Sulfatase Deficiency
- Principal Investigator
  
  ETO Yoshikatsu
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Jikei University School of Medicine
Modified enzyme which target to neuronal cells to cross blood brain barrier
- Principal Investigator
  
  ETO Yoshikatsu
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Jikei University School of Medicine
The Pathogenesis of Demyelination in Krabbe's disease and it's therapyPrincipal Investigator
- Principal Investigator
  
  TOKORO Toshiharu
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The Jikei University School of Medicine, Department of Pediatrics

1. ETO Y. (50056909)

# of Collaborated Projects : 11results

# of Collaborated Products : 0results
2. IDA Hiroyuki (90167255)

# of Collaborated Projects : 9results

# of Collaborated Products : 0results
3. ITO F. (10057010)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
4. OHASHI T. (60160595)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
5. UMEZAWA Fusayo (50185063)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
6. MAEKAWA K. (80056613)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
7. 長谷川頼康 (60256435)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. SASAKI Nobuhiko (50170684)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
9. TATSUSHIMA H. (70190460)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
10. 津田隆 (50188554)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. 奈良隆寛 (80180537)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. SAKURAI S. (20056542)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. 五味渕一三 (50205621)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. TOYODA Shigeru (90110931)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. KUSANO Kaoru (80205070)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. ONO Tsuneya (60147288)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. 大野京子 (10301524)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. 小林博司 (90266619)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. SEKIGUCHI Shigeru (90119818)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

TOKORO T. 所 敏治

Research Projects

Co-Researchers

Treatment for congenital metabolic disorder with brain dysfunction.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

リピドーシス動物モデルを用いての中枢神経障害の遺伝子治療

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Analysis and Gene Therapy in Inherited dysmyelinating disorder

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene therapy for inherited neurodegenerative disease using fetal bone marrows stem cell transplantation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies of genetic analysis and gene therapy for myelin-associated disorders.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic analysis of Niemann-Pick model mouse.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

リピド-シスマウス神経細胞に於けるガングリオシド代謝とその機能異常の解明

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Cellular engineering for treatment of animal model for inherited brain disorder

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenesis of Multiple Sulfatase Deficiency

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modified enzyme which target to neuronal cells to cross blood brain barrier

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Pathogenesis of Demyelination in Krabbe's disease and it's therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TOKORO T. 所敏治