OKABE Akinobu 岡部昭延

Researcher Number	20093677
Other IDs
Affiliation (based on the past Project Information) *help	2014: 中国学園大学, 公私立大学の部局等, 教授 2011 – 2014: 中国学園大学, 現代生活学部, 教授 2009 – 2010: Kagawa University, 医学部, 教授 2006 – 2007: 香川大学, 医学部, 教授 2004: Kagawa University, Molecular Microbiology, Professor, 医学部, 教授 … More 2003: 香川大学, 医学部, 教授 1996 – 2002: 香川医科大学, 医学部, 教授 1999: 香川医大, 医学部, 教授 1990 – 1994: Kagawa Medical School Professor, 医学部, 教授 1987 – 1989: 香川医科大学, 医学部, 助教授 1986: Kagawa Medical School, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / 細菌学 / Bacteriology (including mycology) Except Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / Pathological medical chemistry / Neurochemistry/Neuropharmacology / 細菌学
Keywords	Principal Investigator Clostridium perfringens / ウェルシュ菌 / ウエルシュ菌 / α毒素 / phospholipase C / 遺伝子発現 / Bent DNA / Clostridium / ε毒素 / Receptor … More / Epsilon-toxin / フェレドキシン / クロストリジウム / コラゲナーゼ / Collagenase / 細菌毒素 / Histotoxicity / Bacterial toxin / ホスホリパーゼC / 転写調節 / DNA結合蛋白 / Epsilon-Toxin / Lipid rafts / Nephrotoxicity / MDCK cell / Histopathology / 脂質ラフト / イプシロン毒素 / LrpC / Lactobacillus casei / 水素ガス / ガス産生 / ヒドロゲナーゼ / 酪酸 / 遺伝子投与 / バイオリアクター / pyruvate:ferredoxin酸化還元酵素 / Clostridium perfringerns / 発現ベクター / ベントDNA / シアリダーゼ / Ferredoxin gene / Expression vector / Sialidase / Transcriptional fusion / Phased A-tracts / Curved DNA / clostripain / プロテアーゼ / 病原因子 / 凝集性 / Clostripain / クロストリパン / リンカーペプチド / ガス壊疽 / eat-meシグナル / リンカー・ペプチド / フオスフオリパ-ゼC / アルファ毒素 / 遺伝子解析 / フォスフォリパ-ゼC / Nucleotide sequence / Arginine box / C. perfringens / alpha-toxin gene / gene expression / 毒素遺伝子 / 組織侵襲 / θ毒素 / κ毒素 / C.perfringens / Toxin genes / 折れ曲がりDNA / C.peerfringens / alpha-toxin / DNA binding protein / gene regulation / bent DNA / DNA結合タンパク / 遺伝子クローニング / 分子生物学 / 細菌の遺伝子発現 / DNA-binding protein / Gene cloning / Phospholipase C / Molecular biology / レセプター / 毒素複合体 / シナプトソーム / 免疫染色 / 膜可溶化 / Toxin complex / Synaptosome / Immunostaining / Membrane solubilization / Histoparhology / Immunohistochemistry / 構造解析 / 腸性毒素血症 / モノクローナル抗体 / 膜孔形成型毒素 / Immunohistochemsitry / 血小板凝集 / シグナル伝達 / ガングリオシド / スフィンゴミエリン / 血小板 / 脂質クラフト / スフィンゴ糖脂質 / セラミド / Alpha-toxin / Lipid raft / Platelet aggregation / Signal transduction / Ganglioside / Sphingomyelin / イブシロン毒素 / Transcriptional factor / Gene expression / 菌体成分 / プラスミド複製 / 阻害因子 / プラスミドコピー数 / Bacterial components / Plasmid replication / Replication inhibitor … More Except Principal Investigator Clostridium perfringens / phased A-tracts / CaM kinase II / LTP / NMDA / hyaluronidase / ウェルシュ菌 / 糖鎖分解酵素 / 発現系 / 病原性 / 細胞接着 / 細胞外マトリックス蛋白質 / ミクロフィブリル / RGD蛋白質 / 36kDaMAGP / エラスチン / カルシウムイオン / 染色体異常 / 36kDa MAGP / Smith-Magenis症候群 / ミクロフィブリン / extracellular matrix protein / Ca^<2+> binding protein / Smith-Magenis syndrome / elasith / EF hand protein / blood vessel / microfibril / inhibitor / ウエルシュ菌 / ε-毒素 / λ-毒素 / マウス致死活性 / 海馬 / トリプシン / ε毒素 / 組換え毒素 / epsilon-toxin / lambda-toxin / mouse lethality / hippocampus / trypsin / ホスホリパーゼC / 転写調節 / ベントDNA / RNAポリメラーゼ / UPエレメント / phospholipase C / transcriptional regulation / RNA polymerase / Calbrain / 脳 / S-100 / 低体温 / アルコール依存症 / カルシウム結合蛋白質 / 記憶 / Ca^<2+> / calmodulin-dependent protein kinase II / calcineurin / NMR / calbrain / S100 / brain / hypothermia / alcoholism / 下痢原性大腸菌 / 細胞付着性因子 / 細胞毒素 / クレブシラ・オキシトーカ / クロストリディウム・パーフリンゲンス / 溶血毒(A毒素) / フォスフォリパーゼC(α毒素) / 細菌の細胞付着性 / 病原性因子の遺伝子クローニング / クレブシェラ / オキシトーカ / クロストリジウム / パーフリンゲンス / 病原性大腸菌 / 易熱性腸管毒素 / 細菌病原性因子 / プラスミド / 細胞毒性 / K.oxytoca / コンテロトキシン / tox遺伝子 / Diarrheagenic E / coli / Cell adherence factor / Cytotoxin / K / oxytoca / gene cloning / C / perfringens / Perfringolysin Less

バイオガス生産に向けたウェルシュ菌の遺伝子改変に関する研究Principal Investigator
- Principal Investigator
  
  岡部昭延
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Chugoku Gakuen University
Functional and pathogenic analysis of carbohydrate-active enzymes from Clostridium perfirngens
- Principal Investigator
  
  MIYATA Shigeru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Chubu University
A mechanism for regulation of clostripain activity and modification of inflammatory response by the enzyme.Principal Investigator
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Chugoku Gakuen University
  Kagawa University
A study on a mechanism for the transcriptional regulation of an epsilon-toxin gene by a novel type of bent DNAPrincipal Investigator
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kagawa University
A study on the mechanism underlying the action of Clostridium perfringens alpha- and epsilon-toxins to membrane lipid raftsPrincipal Investigator
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  KAGAWA UNIVERSITY
  香川大学(医学部)
特殊ベント・プロモーターを利用した新規高発現ベクターの構築Principal Investigator
- Principal Investigator
  
  岡部昭延
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  香川大学(医学部)
Study on structure biology and molecular pathology of Clostridium perfringens epsilon-toxinPrincipal Investigator
- Principal Investigator
  
  OKABE akinobu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kagawa Medical University
水素ガス産生用ウエルシュ菌バイオリアクター開発のための基礎研究Principal Investigator
- Principal Investigator
  
  岡部昭延
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  香川医科大学
Studies on neurotropism of Clostridium perfringens epsilon-toxin and molecular mechanism of its toxicity toward neuronal cellsPrincipal Investigator
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kagawa Medical University
Neuron specific calcium-binding Protein, calbrain, is involved in memory formation.
- Principal Investigator
  
  TOKUDA Masaaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  KAGAWA MEDICAL UNIVERSITY
Function of promoter upstream bent DNA of the Clostridium perfringens phospholipase C gene
- Principal Investigator
  
  KATAYAMA Seiichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kagawa Medical University
Pathobiological role of 36 kDa microfibril-associated glycoprotein in Smith-Magenis syndrome.
- Principal Investigator
  
  KOBAYASHI Ryoji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagawa Medical University
Analysis of the activation and mode of action of Clostridium perfringens ε-toxin
- Principal Investigator
  
  MATSUSHITA Osamu, 南純三朗
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kagawa Medical University
Study on function of phospholipase C gene binding protein from Clostridium perfringensPrincipal Investigator
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kagawa Medical University
Function of protein (s) which can bind to an alpha-toxin gene of Clostridium perfringensPrincipal Investigator
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kagawa Medical School
Roles of the alpha-,theta-,and k-toxins in histotoxicity of Clostridium perfringensPrincipal Investigator
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Kagawa Medical School
Analysis of the Alpha-Toxin Gene of Clostridium PerfringensPrincipal Investigator
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Kagawa Medical School
Pathogenic factors of cell adherent Escherichia coli
- Principal Investigator
  
  HAYASHI Hideo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  細菌学
- Research Institution
  Kagawa Medical School
Factors of Lactobacillus casei which inhibit plasmid replicationPrincipal Investigator
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Kagawa Medical School

All 2014 2012 2011 2010 2008 2007 2005 Other

All Journal Article Presentation Book

[Book] 最新細菌・カビ・酵母図鑑2007
- Author(s)
  岡部昭延
- Total Pages
  228
- Publisher
  技術情報協会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590428
[Journal Article] X-ray structure of a novel endolysin encoded by episomal phage phiSM101 of Clostridium perfringens2014
- Author(s)
  Eiji Tamai, Hiromi Yoshida, Hiroshi Sekiya, Hirofumi Nariya, Shigeru Miyata, Akinobu Okabe, Tomomi Kuwahara, Jun Maki, and Shigehiro Kamitori
- Journal Title
  
  Molecular Microbiology
  
  Volume: 92 Pages: 326-337
- Data Source
  KAKENHI-PROJECT-24590538
[Journal Article] ウェルシュ菌の自己凝集性に関する研究2012
- Author(s)
  坂本知世、杉井美香、平田知之(担当教員岡部昭延)
- Journal Title
  
  平成23年度卒業研究中国学園大学現代生活学部人間栄養学科7期生
  
  Pages: 68-72
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] Development and characterization of a xylose-inducible gene expression system for Clostridium perfringens2011
- Author(s)
  Hirofumi Nariya, Shigeru Miyata, Tomomi Kuwahara, and Akinobu Okabe
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 77-23 Pages: 8439-8441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] High-level production and purification of clostripain expressed in a virulence-attenuated strain of Clostridium perfringens2011
- Author(s)
  Hiroaki Tanaka, Hirofumi Nariya, Motoo Suzuki, Hitoshi Houchi, Eiji Tamai, Shigeru Miyata, and Akinobu Okabe
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 76-1 Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] Development and application of a method for counterselectable in-frame deletion in Clostridium perfringens2011
- Author(s)
  Hirofumi Nariya, Shigeru Miyata, Motoo Suzuki, Eiji Tamai, and Akinobu Okabe
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 77-4 Pages: 1375-1382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] Development and characterization of a xylose-inducible gene expression system for Clostridium perfringens2011
- Author(s)
  Hirofumi Nariya, Akinobu Okabe
- Journal Title
  
  Applied and Enviromental Microbiology
  
  Volume: 77 Pages: 8439-8441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] Identification and characterization of a putative endolysin encoded by episomal phage phiSM101 of Clostridium perfringens2011
- Author(s)
  Hirofumi Nariya, Akinobu Okabe
- Journal Title
  
  Applied Microbiology and Biotechnology
  
  Volume: 90 Pages: 1973-1979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] Identification and characterization of a putative endolysin encoded by episomal phage phiSM101 of Clostridium perfringens2011
- Author(s)
  Hirofumi Nariya, Shigeru Miyata, Eiji Tamai, Hiroshi Sekiya, Jun Maki, and Akinobu Okabe
- Journal Title
  
  Applied Microbiology and Biotechnology
  
  Volume: 90-6 Pages: 1973-1979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] Purification and characterization of a clostripain-like protease from a recombinant Clostridium perfringens culture2010
- Author(s)
  Akinobu Okabe
- Journal Title
  
  Microbiology 156
  
  Pages: 561-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] Purification and characterization of a clostripain-like protease from a recombinant Clostridium perfringens culture2010
- Author(s)
  Sadao Manabe, Hirofumi Nariya, Shigeru Miyata, Hiroaki Tanaka, Junzaburo Minami, Motoo Suzuki, Yuki Taniguchi, and Akinobu Okabe
- Journal Title
  
  Microbiology
  
  Volume: 156-2 Pages: 561-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] ウェルシュ菌のClostripain-like proteaseの病原的意義についての研究2010
- Author(s)
  岡部昭延
- Journal Title
  
  乳酸菌研究会に関する報告書
  
  Pages: 300-303
- Data Source
  KAKENHI-PROJECT-21590483
[Journal Article] Construction and characterization of a clostripain-like protease-deficient mutant of Clostridium perfringens as a strain for clostridial gene expression2008
- Author(s)
  Tanaka H, Tamai E, Miyata S, Taniguchi Y, Nariya H, Hatano N, Houchi H, Okabe A.
- Journal Title
  
  Applied Microbiology and Biotechnology 77
  
  Pages: 1063-1071
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590428
[Journal Article] Construction of a clostripain-like protease mutant and its application2007
- Author(s)
  Okabe, A., Tanaka, H., Miyata, S., Tamai, E
- Journal Title
  
  Annual Report of Studies on Lactic Acid Bacteria
  
  Pages: 437-443
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590428
[Journal Article] ウエルシュ菌のプロテアーゼ・ノックアウト株の構築と利用について2007
- Author(s)
  岡部昭延, 田中裕章, 宮田茂, 玉井栄治
- Journal Title
  
  乳酸菌研究会に関する報告書 18年度版
  
  Pages: 437-443
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590428
[Journal Article] Changens in ganglioside content affect the binding of Clostridium perfringens epsilon-toxin to detergent-resistant membranes of Madin-Darby canine kidney cells.2005
- Author(s)
  Shimamoto S, Tamai E, Matsushita O, Minami J, Okabe A, Miyata S.
- Journal Title
  
  Microbiology and Immunology 49(3)
  
  Pages: 245-253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390144
[Journal Article] Construction and characterization of a clostripain-like protease-deficient mutant of Clostridium perfringens as a strain for clostridial gene expression
- Author(s)
  Tanaka, H., Tamai, E., Miyata, S., Taniguchi, Y., Nariya, H., Hatano, N., Houchi H, Okabe, A
- Journal Title
  
  Applied Microbiology and Biotechnology 77(5)
  
  Pages: 1063-1071
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590428
[Presentation] Clostridium perfringensの菌体表面のglyceraldehyde-3-phosphate dehydro-genaseの研究2011
- Author(s)
  岡部昭延、宮田茂、成谷宏文
- Organizer
  全国乳酸菌研究会中国四国支部会
- Place of Presentation
  岡山ホテルグランヴィア
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21590483
[Presentation] Development and characterization of a xylose-inducible gene expression system for Clostridium perfringens2011
- Author(s)
  Hirofumi Nariya, Shigeru Miyata, and Akinobu Okabe
- Organizer
  XIII International Congress of Bacteriology and Applied Microbiology, International Union of Microbiological Societies Congresses 2011
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-21590483
[Presentation] High-level production and purification of clostripain expressed in a virulence-attenuated strain of Clostridium perfringens2011
- Author(s)
  Hiroaki Tanaka, Hirofumi Nariya, Motoo Suzuki, Shigeru Miyata, Eiji Tamai, Shinji Kosaka, Noriyasu Fukuoka, Hitoshi Houchi, and Akinobu Okabe
- Organizer
  XIII International Congress of Bacteriology and Applied Microbiology, International Union of Microbiological Societies Congresses 2011
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-21590483
[Presentation] ウェルシュ菌のglyceraldehyde-3-phosphate dehydrogenaseの性状解析2010
- Author(s)
  田中裕章, 成谷宏文, 鈴木基生, 谷口有紀, 芳地一, 宮田茂, 岡部昭延
- Organizer
  第63回日本細菌学会中国・四国支部総会
- Place of Presentation
  松山
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-21590483
[Presentation] Clostridium 属のクロストリパインの量産と精製および性状解析について2010
- Author(s)
  岡部昭延
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21590483

1. MATSUSHITA Osamu (00209537)

# of Collaborated Projects: 12 results

# of Collaborated Products: 1 results
2. KATAYAMA Sei-ichi (70169473)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. MIYATA Shigeru (90314913)

# of Collaborated Projects: 8 results

# of Collaborated Products: 15 results
4. MINAMI Junzaburo (40157566)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
5. KOBAYASHI Ryoji (00020917)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. TOKUDA Masaaki (10163974)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. TAMAI Eiji (40333512)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
8. NARIYA Hirofumi (30452668)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
9. TOKUMITSU hiroshi (20237077)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. HAYASHI Hideo (40033203)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. SUZUKI Motoo (80457340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. MORIYAMA Ryuichi (60191061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YOSHIDA Hiromi (10313305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. NAKAKITA Shinichi (40314356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SATO Chubun (20032815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUGANUMA Tatsuo (60115350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MAETA Hajime (00075508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SUGIMOTO Katsuyoshi (80322270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TAKEUCHI Yoshiki (20116619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ITANO Toshifumi (60145042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 前田肇 (20294754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 山口文徳 (40271085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OKABE Akinobu 岡部 昭延

Research Projects

Research Products

Co-Researchers

バイオガス生産に向けたウェルシュ菌の遺伝子改変に関する研究Principal Investigator

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Functional and pathogenic analysis of carbohydrate-active enzymes from Clostridium perfirngens

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A mechanism for regulation of clostripain activity and modification of inflammatory response by the enzyme.Principal Investigator

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A study on a mechanism for the transcriptional regulation of an epsilon-toxin gene by a novel type of bent DNAPrincipal Investigator

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A study on the mechanism underlying the action of Clostridium perfringens alpha- and epsilon-toxins to membrane lipid raftsPrincipal Investigator

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特殊ベント・プロモーターを利用した新規高発現ベクターの構築Principal Investigator

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Study on structure biology and molecular pathology of Clostridium perfringens epsilon-toxinPrincipal Investigator

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水素ガス産生用ウエルシュ菌バイオリアクター開発のための基礎研究Principal Investigator

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Studies on neurotropism of Clostridium perfringens epsilon-toxin and molecular mechanism of its toxicity toward neuronal cellsPrincipal Investigator

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Neuron specific calcium-binding Protein, calbrain, is involved in memory formation.

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Function of promoter upstream bent DNA of the Clostridium perfringens phospholipase C gene

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Pathobiological role of 36 kDa microfibril-associated glycoprotein in Smith-Magenis syndrome.

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Analysis of the activation and mode of action of Clostridium perfringens ε-toxin

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OKABE Akinobu 岡部昭延