NAKAZAWA Hiroe 中澤博江

Researcher Number	20110885
Other IDs
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Affiliation (based on the past Project Information) *help	1995 – 2006: Tokai University, school of medicine Professor, 医学部, 教授 1994: Tokai Univ.school of Medicine Dept.of Physiology, professor, 医学部・生理科学, 教授 1993: 東海大学, 医学部, 助教授 1993: 東海大学医学部, 生理2, 助教授 1988 – 1990: Associate Professor of Medicine, Tokai University, 医学部, 助教授 1987: 東海大学, 医学部, 講師 1987: 東海大学, 医学部・生理学教室, 講師
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / General physiology / General physiology Except Principal Investigator Circulatory organs internal medicine / Radiation science / Plastic surgery / Neurology / Respiratory organ internal medicine / Clinical nursing / Kidney internal medicine / Neurology
Keywords	Principal Investigator nitric oxide / 一酸化窒素 / peroxynitrite / パーオキシナイトライト / スーパーオキサイド / cytotoxicity / NO合成酵素 / superoxide / PAI-1 / eNOS … More / iNOS / nNOS / NADPH / NO synthase / 培養心筋細胞 / NADPHオキシターゼ / キサンチンオキシターゼ / tissue injury / Superoxide / Coenzyme Q_<10> Radical / Myocardium / Coenzyne Q_<10>アニオンラジカル / Coenzyme Q_<10>アニオンラジカル / 虚血 / CoenzymeQ_<10>アニオンラジカル / 心筋 / Reactive oxygen species (ROS) / Cardiovascular system / Redox / 活性酸素 / 心・血管系 / レドックス / macrophage / LDL oxidation / knock out / マクロファージ / LDL酸化 / ノックアウト / heme-iron / arginine / tetrahydrobiopterin (BH4) / nitric oxide synthase / ヘム / テトラバイオオプテリン / テトラバイオプテリン / ヘム鉄 / アルギニン / テトラバイオプテリン(BH_4) / nitrotyrosine / endotoxin-shock / brain ischemia / ニトロチロシン / エンドトキシンショック / 脳虚血 / 細胞障害 / NO-electrode / hemoglobin / Cylotoxicity / Cytotoxicity / Cyto Toxicity / NO / Reperfusion Injury / active oxygen / myocyte / NADPHオキシダーゼ / キサンチンオキシダーゼ / 化学発光 / 再潅流 / ESR / 再灌流 / フリ-ラジカル … More Except Principal Investigator 遺伝子導入 / NO / 遺伝子治療 / neuronal cell death / 7-nitro indazole / peroxynitrite / 3-nitro-L-tyrosine / nitric oxide / inducible nitric oxide synthase / cerebral ischemia / aminoguanidine / マクロファージ / 放射線肺臓炎 / 培養皮膚 / 脳虚血 / Free Radicals / Myocardium / Metabolism / Reperfusion Injury / 虚血 / CoenzymeQ_<10>アニオンラジカル / 心筋 / 再灌流 / NMR / ESR / 再潅流 / フリ-ラジカル / ^<31>P-nuclear magnetic resonance / Chronic respiratory failure / Hypoxia / ^<31>PーNMR / 慢性低酸素曝露 / ATP / 呼吸不全運動負荷 / 高エネルギー燐酸化合物 / ^<31>P核磁気共鳴法 / 呼吸不全 / 低酸素状態 / uncoupling reaction / superoxide / tetrahydrobiopterine / cellular signal transducation / endothelial cells / reactive oxygen species / nitric oxide synthase / 8ニトログアノシン / 脱共役 / スーパーオキサイド / テトラヒドロビオプテリン / 細胞情報伝達 / 血管内皮 / 活性酸素 / 一酸化窒素合成酵素 / VISUALEARN Q&A / Adult Nursing / Case Study / Basic Nursing Education / Nursing Intervention / Nursing Diagnosis / Clinical Judgment / e-Learning / 事例学習法 / 医療情報学 / デジタル教材開発 / 事例学習 / ビジュランQ&Aシステム / 成人看護学 / 事例演習 / 看護基礎教育課程 / 看護介入 / 看護診断 / 臨床判断能力 / デジタル教材 / gene transfer / angiogenesis / vascular inductio / cultured skin / 血管新生 / 血管誘導 / Bioartificial Kidney / Artifickal membrane / Gene transfection / Aquaporin 1 DNA / LLC-PK1 cells / Hybrid artificial tubules / Tubular epithelial cells / アクアポリン1 / ハイブリッド人工尿細胞 / バイオ人工腎臓 / 人工膜 / アクアポリン1遺伝子 / LLC-PK_1細胞 / ハイブリッド人工尿細管 / 尿細管上皮細胞 / microangiography / synchrotroon radiation / 循環障害 / 単色放射光 / 血管造影法 / 放射光 / CNOO^- / Nitrotyrosine / ONOO^- / モノクロタリン / カテーテル / 原発性肺高血圧症 / 脳梗塞症 / カテール治療 / 肝細胞癌 / 難治性疾患 / カテーテル治療 / 気管支肺胞洗浄 / リニアック / 急性期肺障害 / 胸部CT写真 / 細胞移植療法 / 蛋白質付着抑制 / 拒絶反応抑制表面 / ミクロドメイン構造 / 親水基密度 / 光表面改質 / プラズマ・光併用照射効果 / ドーパミン産生細胞 / パーキンソン病 / アポトーシス / ウイルスベクター / 急性肺障害 / 細胞培養 / metomyoglobin / L-NMMA / 脳血流 / Glutamate / 一酸化窒素 Less

The development of the transcatheter therapy using cationized gelatine in various disease
- Principal Investigator
  
  FUKUYAMA Naoto
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Tokai University
放射線肺臓炎における再生医療の検討
- Principal Investigator
  
  玉井好史
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Tokai University
パーキンソン病治療用ドパミン産生細胞培養セル・チップの開発
- Principal Investigator
  
  村原正隆
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Tokai University
遺伝子を用いた放射線肺臓炎に対する新しい治療法
- Principal Investigator
  
  FUKUYAMA Naoto
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Tokai University
Redox-regulation by active oxygen species / nitric oxide in cardiovascular systemPrincipal Investigator
- Principal Investigator
  
  NAKAZAWA Hiroe
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokai University
遺伝子導入培養皮膚を利用した新しい遺伝子療法の開発
- Principal Investigator
  
  宮坂宗男
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Plastic surgery
- Research Institution
  Tokai University
The development of the vascular inducible cultured skin substitute (VICSS).
- Principal Investigator
  
  TANINO Ryuzaburo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Tokai University
The Development and Testing of Digital teaching materials to Cultivate Students' Abilities in Clinical Judgment.
- Principal Investigator
  
  FUJIMURA Ryuko
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical nursing
- Research Institution
  Tokai University
Generation of reactive oxygen species and intracellular signal transduction mediated by nitric oxide synthases
- Principal Investigator
  
  ICHIMORI Kohji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Institute of Advanced Industrial Science and Technology
  Tokai University
Development of Hybrid Bioartificial Tubules using Tubular Epithelial Cells
- Principal Investigator
  
  SAITO Akira
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
Role of Inducible NO Synthase (iNOS) on Atherosclerosis -Study of iNOS-Knock out Mice-Principal Investigator
- Principal Investigator
  
  NAKAZAWA Hiroe
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Tokai University
Analysis of Electron Flow in Nitric Oxide SynthasePrincipal Investigator
- Principal Investigator
  
  NAKAZAWA Hiroe
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokai University
Development of a new dual-contrast microangiographic system by using monochromatic synchrotron radiation
- Principal Investigator
  
  TANAKA Etsuro
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokai University
Dynamics of nitric oxide (NO) in biological miliue and mechanism of NO-induced injury.Principal Investigator
- Principal Investigator
  
  NAKAZAWA Hiroe
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokai University
The study concerning the formation of peroxynitrite in focal ischemia-reperfusion
- Principal Investigator
  
  TAKIZAWA Shunya
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokai University
脳虚血における一酸化窒素とグルタミン酸放出との関連について
- Principal Investigator
  
  TAKIZAWA Shunya
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokai University
Investigation to develop a nitric oxide-selective electrodePrincipal Investigator
- Principal Investigator
  
  NAKAZAWA Hiroe
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokai University School of Medicine
Cytotoxicity of Superoxide and Nitric Oxide (NO)Principal Investigator
- Principal Investigator
  
  NAKAZAWA Hiroe, 中澤博江
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Tokai University
Interaction and Cytotoxic Effect of Superoxide and NO in Reperfusion InjuryPrincipal Investigator
- Principal Investigator
  
  NAKAZAWA Hiroe
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokai university school of medicine
再灌流時におけるラジカル発生の直接証明Principal Investigator
- Principal Investigator
  
  中澤博江
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokai University
Free Radicals and Metabolic State of the Reperfused Myocardium
- Principal Investigator
  
  OKINO Haruka
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  TOKAI UNIVERSITY
Pathophysiological investigation of respiratory failure;Changes in energy metabolism using ^<31>P-NMR method
- Principal Investigator
  
  YAMABAYASHI Hajime
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tokai University
The Clarification of Mechanisms for Electron Transfer and Identification of Radicals in MyocardiumPrincipal Investigator
- Principal Investigator
  
  NAKAZAWA Hiroe
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokai University

All 2008 2007 2006 2005 2003 2001

All Journal Article

[Journal Article] Validation of the Friedewald Equation for Evaluation of Plasma LDL-Cholesterol.2008
- Author(s)
  N. Fukuyama, K. Homma, N. Wakana, K. Kudo, A. Suyama, H. Ohazama, C. Tsuji, K. Ishiwata, H. Nakazawa, E. Tanaka.
- Journal Title
  
  J. Clin. Biochem. Nutr. 43
  
  Pages: 1-5
- NAID
  130004466520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390336
[Journal Article] Activation of Inducible nitric Oxide Synthase Increases MMP-2 and MMP-9 Levels in ApoE-knockout Mice.2008
- Author(s)
  Y. Chen, Y. Aratani, T. Osawa, N. Fukuyama, C. Tsuji, H. Nakazawa
- Journal Title
  
  Tokai J Exp Clin Med. vol.33, No. 1
  
  Pages: 28-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390336
[Journal Article] Intravenous injection of phagocytes transfected ex vivo with FGF4 DNA/ biodegradable gelatin complex promotes angiogenesis in a rat myocardial ischemia/reperfusion injury model. Basic Research in Cardiology.2007
- Author(s)
  N. Fukuyama, E. Tanaka, Y. Tabata, H. Fujikura, M. Hagihara, H. Sakamoto, K. Ando, H. Nakazawa, H. Mori.
- Journal Title
  
  Basic Res Cardiol. 102(3)
  
  Pages: 209-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390336
[Journal Article] 黒酢もろみ末による大腸癌の抑制効果 -ヒト大腸癌細胞を移植した動物モデルを用いて-2007
- Author(s)
  静間徹、石渡一夫、中澤博江、長野正信、盛英三、福山直人
- Journal Title
  
  静脈経腸栄養 22(3)
  
  Pages: 337-342
- NAID
  10019782965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390336
[Journal Article] moromimatsu inhibits tumor growth of Lovo cells in a mouse model in vivo.2007
- Author(s)
  Fukuyama, N., Jujo, S., Ito, I., Shizuma, T., Myojin, K., Ishiwata, K., Nagano, M., Nakazawa, H., Mori, H. Kurozu
- Journal Title
  
  Nutrition 23 (1)
  
  Pages: 81-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390336
[Journal Article] 沖縄モズク由来アセチルフコイダンの癌抑制効果2007
- Author(s)
  石渡一夫、静間徹、中澤博江、盛英三、福山直人
- Journal Title
  
  静脈経腸栄養 22(4)
  
  Pages: 489-494
- NAID
  10026891755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390336
[Journal Article] Triiodothyronine acutely increases blood flow in the ventricles and kidneys of anesthesized rabbits.2006
- Author(s)
  Kimura K, Shinozaki Y, Fukuyama N, Nakazawa H, et al.
- Journal Title
  
  Thyroid (in press)
- Data Source
  KAKENHI-PROJECT-17659375
[Journal Article] Triiodothyronine acutely increase blood flow in the ventricles and kidneys of anesthesized rabbits.2006
- Author(s)
  Kimura K, Shinozaki Y, Jujo S, Shizuma T, Fukuyama N, Nakazawa H.
- Journal Title
  
  Thyroid 16(4)
  
  Pages: 357-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390336
[Journal Article] Results of screening with liver cancer patients for the hepatitis B and C viral markers.2005
- Author(s)
  Khurelbaatar N, N.Fukuyama, H.Nakazawa.
- Journal Title
  
  J Health Science UB 1
  
  Pages: 111-114
- Data Source
  KAKENHI-PROJECT-17659375
[Journal Article] Myeloperoxidase has directly-opposed effects on nitration reaction-study on myeloperoxidase-deficient patient and myeloperoxidase-knockout mice2003
- Author(s)
  Ichimori K, Fukuyama N, Nakazawa H, Aratani Y, Koyama H, Takizawa S, Kameoka Y, Ishida-Okawara A, Kohi F, Suzuki K.
- Journal Title
  
  Free Radic Res 37
  
  Pages: 481-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670745
[Journal Article] Regulation of inducible nitric oxide synthase by self-generated NO2001
- Author(s)
  Abu-Soud HM, Ichimori K, Nakazawa H, Stuehr DJ.
- Journal Title
  
  Biochemistry 40
  
  Pages: 6876-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670745

1. ICHIMORI Kouji (60184636)

# of Collaborated Projects: 11 results

# of Collaborated Products: 2 results
2. ISHIDA Hideyuki (20222424)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. FUKUYAMA Naoto (50349338)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. MORI Hidezo (90146598)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. OKINO Haruka (60055689)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TSUJI Chizuko (80130079)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
7. TAMAI Yoshifumi (90207225)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. TAKIZAWA Shunya (70197234)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. INOKUCHI Sadaki (60160008)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. TANINO Ryuzaburo (50051595)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. TANAKA Etsuro (80211366)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. NAGATA Naruhiko (60307254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HYODO Kazuyui (60201729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SAITO Akira (60307296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KIMURA Minoru (10146706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KAKUTA Takatoshi (50276854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. FUJIMURA Ryuko (90070763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ARITA Kiyoko (00276875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. EGAWA Kouji (90276808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ONISHI Chiemi (00134354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NAGASE Masako (90338765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TAKEKOSHI Susumu (70216878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. GOTO Shinya (50225653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. YAMABAYASHI Hajime (60055697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KUTSUZAWA Tomoko (10183310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. SHIOYA Sumie (20102840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. YAMAMOTO Masahiro (80095661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 宮坂宗男 (40190756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 赤松正 (10276850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 村原正隆 (40166301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 野元正弘 (50208401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 吉井文均 (90130103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 大山龍一郎 (40233291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 二木鋭雄 (20011033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 中澤博江 (20110588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 時政孝行 (50155511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 村中陽子 (30132195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. LASZLO Pronai

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. JANOS Feher

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. SHINOZAKI Yoshiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. UMETANI Keiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. PRONAI Laszl

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. FEHER Janos

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. ABU・SOUD Hus

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. IKEDAーSAITO マサオ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. STUEHR Denni

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAZAWA Hiroe 中澤 博江

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Redox-regulation by active oxygen species / nitric oxide in cardiovascular systemPrincipal Investigator

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Role of Inducible NO Synthase (iNOS) on Atherosclerosis -Study of iNOS-Knock out Mice-Principal Investigator

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Analysis of Electron Flow in Nitric Oxide SynthasePrincipal Investigator

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Dynamics of nitric oxide (NO) in biological miliue and mechanism of NO-induced injury.Principal Investigator

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NAKAZAWA Hiroe 中澤博江