SASAKI Kenji 佐々木健二

… Alternative Names

佐々木健二ササキケンジ

SASSAKI Kenji 佐々木健二

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Researcher Number	20116461
Other IDs
Affiliation (based on the past Project Information) *help	2005 – 2009: 岡山大学, 大学院・医歯薬学総合研究科, 教授 2006: Okayama University, Pharmaceutical Sciences, Professor, 大学院医歯薬学総合研究科, 教授 2002 – 2003: Okayama University Faculty of Pharmaceutical Sciences, Professor, 薬学部, 教授 1999 – 2001: 岡山大学, 薬学部, 助教授 1997: 岡山大学, 薬学部, 助教授 1988 – 1990: Okayama University, 薬学部, 助手 1988: 岡山大学, 薬学部, 教務員
Review Section/Research Field	Principal Investigator Drug development chemistry / 医薬分子機能学 Except Principal Investigator Biological pharmacy / 寄生虫学(含医用動物学) / Chemical pharmacy / Hygiene
Keywords	Principal Investigator 選択毒性 / 抗マラリア薬 / in vivo / in vitro / selective toxicity / quaternary ammonium salt dimer / アミド結合 / N-アルキル鎖 / 熱帯熱マラリア原虫 / 抗マラリア活性 … More / 構造活性相関 / inexpensive / N-alkyl chain / thioether / anti-malarials / リンカー長 / チオエーテル結合 / リンカー / 安価 / チオエーテル / 第4級アンモニウム塩ダイマー / counter-anion / anti-malarial activity / chemotherapeutic reagent / drug resistance / Plasmodium falciparum / anti-malarial / スルフィド結合 / カウンターアニオン / 化学療法剤 / 薬剤耐性 / 第四級アンモニウム塩ダイマー / ダイマー / 第四級アンモニウム塩 / サイクリックケトン / キナゾリン-2,4-ジオン / キナゾリン-4-オン / 熱帯熱マラリア / プリマキン / 培養熱帯熱マラリア / チエノチアゾロナフチリジン / 5-置換チエノナフチリジン / 5-置換フロナフチリジン … More Except Principal Investigator hemoglobin heme / hematinic acid / phenylhydrazine / ピロール / 赤血球 / ガスクロマトグラフィー / ヘモグロビン / ヘマチン酸 / ヘム / フェニルヒドラジン / Mefloquine-resistant / pfmdr1 / New antimalarials / Endoperoxides / Drug-resistant / Malaria / 遺伝子発現 / 熱帯熱マラリア原虫 / マラリア / 遺伝子 / アルテミシニン耐性 / pfmdr 1遺伝子 / 薬剤耐性機構 / 薬剤耐性熱帯熱マラリア / 環状下酸化物 / RNAi / メフロキン耐性 / 遺伝子変異 / pfmdr 1 / 新規抗マラリア薬 / 環状過酸化物 / 薬剤耐性マラリア / 熱帯熱マラリア / 11, 13, 15, 17-Tetraazasteroid / 17-Oxide / B, D-Dihomoazasteroid / B-Homoazasteroid / Antireserpine / Benzocycloheptapyrimidine / 11, 13, 15-Triazasteroid / Antidepression / 11、13、15-トリアザステロイド / B,D-ジホモアザステロイド / B-ホモアザステロイド / アルキルアミン / ベンゾシクロヘプタピリミジン / アザステロイド / 11,13,15,17ーテトラアザステロイド / 17ーオキシド / B,Dージホモアザステロイド / Bーホモアザステロイド / 抗レセルピン / ベンゾシクロヘプタビリミジン / 11,13,15ートリアザステロイド / 抗うつ / 喘息予防 / IL-13 / 一酸化窒素合成酵素(NOS) / 一酸化窒素(NO) / ダニ / サイトカイン / Ngaマウス / NC / 気道抵抗 / 一酸化窒素 / 一酸化窒素合成酵素 / 喘息モデル / 呼気NO / 喘息 / ステロイド / アルギナーゼ阻害剤 / アルギナーゼ / 環境生理 / 予防医学 / 環境保健 Less

Development of preventive and therapeutic method of asthma by the regulation of arginase
- Principal Investigator
  
  OGINO Keiki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Okayama University
Invention of Inexpensive AntimalarialsPrincipal Investigator
- Principal Investigator
  
  SASAKI Kenji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Okayama University
Synthesis and evaluation of the anti-malarial activity of the quaternary ammonium salt dimer as the new anti-malarial candidatePrincipal Investigator
- Principal Investigator
  
  SASAKI Kenji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  OKAYAMA UNIVERSITY
New Antimalarial Drug Research for Multidrug-resistant Malaria
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Okayama University
サイクリックケトン類を3位に持つ4-キナゾロン誘導体の抗マラリア活性の検討Principal Investigator
- Principal Investigator
  
  佐々木健二
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
プリマキンをリ-ド化合物とする抗マラリア薬の開発研究Principal Investigator
- Principal Investigator
  
  佐々木健二
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
Researches of Synthesis and Antidepressive Evaluation of Azasteroid and Its Related Compounds
- Principal Investigator
  
  HIROTA Takashi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Okayama University
Hematinic acid produced by the reaction of phenylhemoglobin with hydrogen peroxide
- Principal Investigator
  
  HIROTA Kazuhiro
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Health Sciences of Okayama University

All 2007 2006

All Journal Article Patent

[Journal Article] Analgesic agents without gastric damage : Design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1- elective inhibitors2007
- Author(s)
  X.Zheng, H.Oda, K.Takamatsu, Y.Sugimoto, A.Tai, E.Akaho, H.I.Ali, T.Oshiki, H.Kakuta, K.Sasaki
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry 15・2
  
  Pages: 1014-1021
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590088
[Journal Article] Analgesic agents without gastric damage : Design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-I-elective inhibitors2007
- Author(s)
  X Zheng, H.Oda, K.Takamatsu, Y.Sugimoto, A.Tai, E.Akaho, H.I.Ali, T.Oshiki, H.Kakuta, K.Sasaki
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry 15・2
  
  Pages: 1014-1021
- Data Source
  KAKENHI-PROJECT-17590088
[Journal Article] Analgesic agents without gastric damage : Design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-elective inhibitors2007
- Author(s)
  X.Zheng, H.Oda, K Takamatsu, Y Sugimoto, A.Tai, E.Akaho, H.LAli T.Oshiki, H.Kakuta, K Sasaki
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry 15
  
  Pages: 1014-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590088
[Journal Article] Antimalarial effect of bis-pyridinium salts, N,N-hexamethylenebis(4-carbamoyl-1-alkylpyridinium bromide)2006
- Author(s)
  K.Fujimoto, D.Morisaki, M.Yoshida, T.Namba, K-H.-Sook, Y.Wataya, H.Kourai, H.Kakuta, K.Sasaki
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry Letters 16・10
  
  Pages: 2758-2760
- Data Source
  KAKENHI-PROJECT-17590088
[Journal Article] Antimalarial effect of bis-pyridinium salts, N,N'-hexamethylenebis(4-carbamoyl-1-alkylpyridinium bromide)2006
- Author(s)
  K.Fujimoto, D.Morisaki, M.Yoshida, T.Namba, K-H.-Sook, Y.Wataya, H.Kourai, H.Kakuta, K.Sasaki
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry letters 16・10
  
  Pages: 2758-2760
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590088
[Journal Article] Antimalarial effect of bis-pyridinium salts, N,N-hexamethylenebis(4-carbamoyl-1-alkylpyridinium bromide)2006
- Author(s)
  Fujimoto, D.Morisaki, M.Yoshida, T.Namba, K-H.-Sook, Y.Wataya, H.Kourai, H.Kakuta, K.Sasaki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 6・10
  
  Pages: 2758-2760
- Data Source
  KAKENHI-PROJECT-17590088
[Journal Article] N, N-hexamethylenebis(4-carbamoy1-1-alkylpyridinium bromide)2006
- Author(s)
  K Fujimoto, D.Morisaki, M.Yoshida, T.Namba, K-H.-Sook, Y.Wataya, H, Kourai, H.Kakuta, K Sasaki
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry letters 16
  
  Pages: 2758-2760
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590088
[Patent] 新規な抗マラリア剤2006
- Inventor(s)
  佐々木健二, 加来田博貴, 日和佐佳子, 本島和典
- Industrial Property Rights Holder
  国立大学法人岡山大学
- Industrial Property Number
  2006-276588
- Filing Date
  2006-10-10
- Data Source
  KAKENHI-PROJECT-17590088
[Patent] 新規な抗マラリア剤2006
- Inventor(s)
  佐々木健二, 加来田博貴, 曰和佐佳子, 本島和典
- Industrial Property Rights Holder
  国立大学法人岡山大学
- Industrial Property Number
  2006-276588
- Filing Date
  2006-10-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590088

1. OGINO Keiki (70204104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. OU Tatsuko (90294404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TAKIGAWA Tomoko (90403493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MAEKAWA Tuyoshi (60034972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IZUMI Tomonori (00261694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OUCHI Kazunobu (80351899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKAMURA Kazuyuki (90107748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIROTA Takashi (00033275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KATSU Takashi (40112156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. WATAYA Yusuke (90127598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MORIYAMA Yoshinori (10150658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NOJIMA Masatomo (80029181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HYES-OOK Kim (70314664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HIROTA Kazuhiro (50029956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 岩藤章正 (10116436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. OGASAWARA Sadanori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SASAKI Kenji 佐々木 健二

佐々木 健二 ササキ ケンジ

SASSAKI Kenji 佐々木 健二

Research Projects

Research Products

Co-Researchers

Development of preventive and therapeutic method of asthma by the regulation of arginase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Invention of Inexpensive AntimalarialsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthesis and evaluation of the anti-malarial activity of the quaternary ammonium salt dimer as the new anti-malarial candidatePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New Antimalarial Drug Research for Multidrug-resistant Malaria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

サイクリックケトン類を3位に持つ4-キナゾロン誘導体の抗マラリア活性の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

プリマキンをリ-ド化合物とする抗マラリア薬の開発研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Researches of Synthesis and Antidepressive Evaluation of Azasteroid and Its Related Compounds

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hematinic acid produced by the reaction of phenylhemoglobin with hydrogen peroxide

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Analgesic agents without gastric damage : Design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1- elective inhibitors2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Analgesic agents without gastric damage : Design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-I-elective inhibitors2007

Author(s)

Journal Title

Data Source

[Journal Article] Analgesic agents without gastric damage : Design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-elective inhibitors2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Antimalarial effect of bis-pyridinium salts, N,N-hexamethylenebis(4-carbamoyl-1-alkylpyridinium bromide)2006

Author(s)

Journal Title

Data Source

[Journal Article] Antimalarial effect of bis-pyridinium salts, N,N'-hexamethylenebis(4-carbamoyl-1-alkylpyridinium bromide)2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Antimalarial effect of bis-pyridinium salts, N,N-hexamethylenebis(4-carbamoyl-1-alkylpyridinium bromide)2006

Author(s)

Journal Title

Data Source

[Journal Article] N, N-hexamethylenebis(4-carbamoy1-1-alkylpyridinium bromide)2006

SASAKI Kenji 佐々木健二

佐々木健二ササキケンジ

SASSAKI Kenji 佐々木健二