IZUMI Tomonori 泉友則

Researcher Number	00261694
Other IDs
Affiliation *help	2016 – 2018 : 山口大学, 医学（系）研究科（研究院）, 准教授 2016 – 2018 : 山口大学, 大学院医学系研究科, 准教授 2010 – 2017 : Yamaguchi University, 医学(系)研究科(研究院), 准教授 2015 : 山口大学, 医学(系)研究科, 准教授 2007 – 2011 : Yamaguchi University, Graduate School of Medicine, Associate Professor … More
Review Section/Research Field	Principal Investigator Emergency medicine / Pathological medical chemistry Except Principal Investigator Emergency medicine / Biomedical engineering/Biomaterial science and engineering / Hematology / General medical chemistry / Hygiene / Embryonic/Neonatal medicine / Tumor diagnostics / Circulatory organs internal medicine
Keywords	Principal Investigator 炎症メディエーター / 細胞表面標識 / 細胞質漏出 / 機能プロテオーム解析 / 疾患マーカー / バイオマーカー / β_2-グリコプロテインI / 病態マーカー / タンパク質相互作用 / 翻訳後修飾 … More Except Principal Investigator Membrane proteins / shotgun proteomics / 糖タンパク質 / アルギナーゼ / 脳神経 / Integrins / 質量分析装置 / 候補蛋白質 / high performance liquid chromatography / protein phosphatase / atherosclerosis / 高脂血症 / 候補タンパク質 / 細胞表面タンパク質 / シュードウリジン / Proteomic analysis / 網羅的プロテオミクス解析 / 一酸化窒素合成酵素 / IL-13 / 軽度低体温療法 / 気道抵抗 / 質量分析計 / 脳脊髄液 / ダニ / 遺伝子診断 / longitudinal SR / 発生分化 / 糖鎖 / therapeutic mild hypothermia / がん細胞 / プロテアーゼ / 発生・分化 / 蛋白質カタログ / 脳障害 / 喘息予防 / 膜蛋白質 / 質量分析機 / 液体クロマトグラフィー / アルギナーゼ阻害剤 / RNA / 質量分析 / 一酸化窒素(NO) / 転写活性 / candidate proteins / MS / ナノフロー高速液体クロマトグラフ / Proteolysis / 血栓症 / 呼気NO / genetic polymorphisms / 発現調節領域 / proteomics / mass spectrometry / クリングルドメイン / 一酸化窒素 / 医師主導型臨床研究 / NC / 網羅的蛋白質解析 / Matrix metalloproteinase / regulatory region / アポリポプロテイン(a) / protein phosphatase 1β / MT1-MMP / 動脈硬化 / 網羅的プロテオーム解析 / lipoprotein (a) / プロテオミクス / severe traumatic brain injury / 脳・神経 / 膜型MMP / 遺伝的多型性 / 喘息モデル / Menbrane proteins / 急性腎障害 / 予防医学 / calcium / プロテオーム解析 / apolipoprotein (a) / transcriptional activity / 網羅的タンパク質解析 / 浸潤装置 / 環境保健 / sarcoplasmic reticulum(SR) / 細胞接着分子 / 表面マーカー / サイトカイン / 尿プロテオーム解析 / Cerebrospinal fluid / インテグリン / 環境生理 / マーカー / iPS細胞 / 尿中バイオマーカー / プラスミノゲン / junctional SR / nano-LC-MS / リポプロテイン(a) / proteome / ryanodine receptor / 重症頭部外傷患者 / 喘息 / 一酸化窒素合成酵素(NOS) / brain protection / Membrane-type MMP / thrombosis / genetic diagnosis / Ngaマウス / ステロイド Less

漏出細胞内タンパク質の新しい細胞外機能：受容体を共有する単球・内皮での役割と作用Principal InvestigatorOngoing
- Principal Investigator
  
  泉友則
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamaguchi University
シュードウリジン：新しいガンマーカーの探索Ongoing
- Principal Investigator
  
  田岡万悟
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnostics
- Research Institution
  Tokyo Metropolitan University
Extracellular function of intracellular proteins released from damaged tissue and bound to monocytes.Principal Investigator
- Principal Investigator
  
  IZUMI Tomonori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamaguchi University
Isolation strategy of iPS cells that enable to maintain under xeno feeder free condition.
- Principal Investigator
  
  Taoka Masato
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Metropolitan University
Comprehensive analysis of intracellular proteins on the cell surface for elucidation of their roles in tissue damage and repair.Principal Investigator
- Principal Investigator
  
  IZUMI Tomonori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamaguchi University
Identification of urinary biomarkers to predict onset of acute kidney injury with proteomic analysis
- Principal Investigator
  
  KASAOKA Shunji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamaguchi University
網羅的プロテオーム解析とプロテオームデータベース構築による救命救急傷病の病態解明
- Principal Investigator
  
  前川剛志
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamaguchi University
Is a novel prognostic marker for post cardiac arrest brain injury beneficial or detrimental?Principal Investigator
- Principal Investigator
  
  IZUMI Tomonori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamaguchi University
Exploration into the Development of New Therapy for Heart Failure by Modifying Sarcoplasmic Reticulum Nanodomain Function
- Principal Investigator
  
  MATSUZAKI Masunori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Development of preventive and therapeutic method of asthma by the regulation of arginase
- Principal Investigator
  
  OGINO Keiki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Okayama University
Distinguishing the effects of maternal environment on the development of fetal brains
- Principal Investigator
  
  FUJIOKA Takashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Yamaguchi University
Protective Effects of Therapeutic Hypothermia in Severe traumatic Brain Injured Patients Evaluated by Large scale Proteome Analyses in Cerebrospinal Fluid
- Principal Investigator
  
  MAEKAWA Tsuyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamaguchi University
β_2-グリコプロテインIの生理機能及び抗リン脂質抗体を介した血栓症の分子機序Principal Investigator
- Principal Investigator
  
  泉友則
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Analysis of the proteolytic events on cell surface through proteomic approach
- Principal Investigator
  
  SEIKI Motoharu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tokyo
Control mechanisms for expression of apolipoprotein (a) gene, a risk factor of thrombosis.
- Principal Investigator
  
  ICHINOSE Akitada
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Yamagata Universtity

All 2016 2013 2012 2011 2009 2008 2007

All Journal Article Presentation

[Journal Article] A mass spectrometry-based method for direct determination of pseudouridine in RNA.2016
- Author(s)
  Yamauchi Y, Nobe Y, Izumikawa K, Higo D, Yamagishi Y, Takahashi N, Nakayama H, Isobe T, Taoka M.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume : 44
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14625
[Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha.2009
- Author(s)
  Toshihiko Izumi
- Journal Title
  
  Arthritis Rheum 60
  
  Pages : 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249071
[Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a nover transcription complex of interleukin enhancer bindine factor 3 and GA binding protein alpha.2009
- Author(s)
  Toshihiko Izumi
- Journal Title
  
  Arthritis Rheum 60
  
  Pages : 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] 損傷細胞から放出されヒト単球細胞株U937細胞表面と相互作用する細胞内タンパク質のプロテオーム解析2013
- Author(s)
  泉友則,横山勝巳,坂井田功
- Organizer
  第86回日本生化学会総会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-23592670
[Presentation] Selective analysis of cell surface-associated proteins : characterization of intracellular proteins that are released from damaged cells and interact with the surface of human monocytic cell line U9372013
- Author(s)
  泉友則,横山勝巳,坂井田功
- Organizer
  第12回HUPOヒトプロテオーム国際会議
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2013-09-17
- Data Source
  KAKENHI-PROJECT-23592670
[Presentation] Selective analysis of cell surface-associated proteins: characterization of intracellular proteins that are released from damaged cells and interact with the surface of human monocytic cell line U937.2013
- Author(s)
  Izumi T, Yokoyama K, Sakaida I
- Organizer
  HUPO 12th Annual World Congress
- Place of Presentation
  PACIFICO Yokohama（Yokohama）
- Data Source
  KAKENHI-PROJECT-23592670
[Presentation] 損傷細胞から放出されヒト単球細胞株U937細胞表面と相互作用する細胞内タンパク質のプロテオーム解析2013
- Author(s)
  泉友則, 横山勝巳, 坂井田功
- Organizer
  第86回日本生化学会総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23592670
[Presentation] パイロット研究:U937細胞表面に結合する細胞内タンパク質の選択的同定2012
- Author(s)
  泉友則,横山勝巳,坂井田功
- Organizer
  日本ヒトプロテオーム学会2012年大会(JHUPO第10回大会)
- Place of Presentation
  東京(日本科学未来館)
- Year and Date
  2012-07-27
- Data Source
  KAKENHI-PROJECT-23592670
[Presentation] パイロット研究：U937細胞に結合する細胞内タンパク質の選択的大規模同定2012
- Author(s)
  泉　友則, 横山勝巳, 坂井田功
- Organizer
  日本プロテオーム学会2012年大会
- Place of Presentation
  日本科学未来館（東京）
- Data Source
  KAKENHI-PROJECT-23592670
[Presentation] 臓器プロテオームの比較解析2011
- Author(s)
  泉　友則、今利詩聖、黒木梨沙、前田有美
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23592670
[Presentation] 敗血症患者血清中のTNFα誘導性タンパク質の動態解析2009
- Author(s)
  秋吉祐樹, 泉友則, 宮内崇, 前川剛志
- Organizer
  第82回日本生化学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] 急性脳障害患者脳脊髄液のショットガンプロテオーム解析2009
- Author(s)
  泉友則
- Organizer
  日本ヒトプロテオーム機構(JHUPO)第7回大会
- Place of Presentation
  東京
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20249071
[Presentation] 心肺停止蘇生後脳症患者脳脊髄液のショットガンプロテオーム解析2009
- Author(s)
  泉友則, 小田泰崇、荒木由佳、大村真裕子、秋吉祐樹、鶴田良介、笠岡俊志、前川剛志
- Organizer
  第4回医学系研究科ライフサイエンスセミナー「ゲノムからプロテオームへ、そして」,日本ヒトプロテオーム機構(JHUPO)第7回サテライトシンポジウム合同会議
- Place of Presentation
  宇部
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] 急性脳障害患者脳脊髄液のショットガンプロテオーム解析2009
- Author(s)
  泉友則, 小田泰崇、荒木由佳、大村真裕子、秋吉祐樹、鶴田良介、笠岡俊志、前川剛志
- Organizer
  日本ヒトプロテオーム機構(JHUPO)第7回大会
- Place of Presentation
  東京
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] 急性脳障害患者脳脊髄液のショットガンプロテオーム解析2009
- Author(s)
  泉友則
- Organizer
  日本ヒトプロテオーム機構(JHUPO)第7回大会
- Place of Presentation
  東京
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] 心肺停止蘇生後脳症患者脳脊髄液のショットガンプロテオーム解析2009
- Author(s)
  泉友則
- Organizer
  第4回医学系研究科ライフサイェンスセミナー「ゲノムからプロテオームヘ、そして」,日本ヒトプロテオーム機構(JHUPO)第7回サテライトシンポジウム合同会議
- Place of Presentation
  宇部市
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] 心肺停止蘇生後脳症患者脳脊髄液のショットガンプロテオーム解析2009
- Author(s)
  泉友則
- Organizer
  第4回医学系研究科ライフサイエンスセミナー「ゲノムからプロテオームヘ、そして」,日本ヒトプロテオーム機構(JHUPO)第7回サテライトシンポジウム合同会議
- Place of Presentation
  宇部市
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20249071
[Presentation] ショットガン法を利用した臨床検体からの大規模タンパク質同定と病態解析への応用2008
- Author(s)
  泉友則
- Organizer
  The 7th Cell Biology Summer Meeting
- Place of Presentation
  鴨川
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-20249071
[Presentation] ショットガン法を利用した臨床検体からの大規模タンパク質同定と病態解析への応用2008
- Author(s)
  泉友則, 前川剛志
- Organizer
  The 7th Cell Biology Summer Meeting
- Place of Presentation
  鴨川
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] 重症頭部外傷患者脳脊髄液の大規模タンパク質解析2008
- Author(s)
  荒木由佳, 大村真裕子, 山下哲平, 秋吉祐樹, 市原清志, 泉友則, 前川剛志
- Organizer
  第49回日本生化学会中国・四国支部例会
- Place of Presentation
  高松
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] SH3結合ドメインを欠くSH3BGR familyタンパク質SH3BGRL3のタンパク質間相互作用2008
- Author(s)
  秋吉祐樹, 泉友則, 大村真裕子, 荒木由佳, 前川剛志
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] 重症頭部外傷における脳脊髄液タンパク質の大規模定量解析2008
- Author(s)
  荒木由佳, 山下哲平, 市原清志, 泉友則, 前川剛志
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] ショットガン法を利用した臨床検体からの大規模タンパク質同定と病態解析への応用2008
- Author(s)
  泉友則
- Organizer
  The 7th Cell Biology Summer Meeting
- Place of Presentation
  鴨川
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-20592121
[Presentation] Proteomics analysis of cerebrospinal fluid from patients with cardidpulmonary resuscitation2007
- Author(s)
  Tomonori Izumi
- Organizer
  HUPO 6th Annual World Congress
- Place of Presentation
  COEX Convention Center(Seoul,Korea)
- Year and Date
  2007-10-09
- Data Source
  KAKENHI-PROJECT-18390480
[Presentation] iTRAQ試薬を利用した脳脊髄液蛋白質の大規模定量解析2007
- Author(s)
  泉友則
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2007-12-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390480
[Presentation] Proteomics analysis of cerebrospinal fluid from patients with cardiopulmonary resuscitation2007
- Author(s)
  Tomonori Izumi
- Organizer
  HUPO 6th Annual World Congress
- Place of Presentation
  COEX Convention Center (Seoul, Korea)
- Year and Date
  2007-10-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390480
[Presentation] Large-scale and quantitative analysis of Cerebrospinal fluid proteins using iTRAQ reagent2007
- Author(s)
  Tomonori, Izumi
- Organizer
  The 30th Annual Meeting of the Molecular Biology Society of Japan, The 80th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Pacifico Yokohama, Yokohama, Japan
- Year and Date
  2007-12-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390480
[Presentation] Proteomics analysis of cerebral fluid from patients with cardiopulmonary resuscitation2007
- Author(s)
  Tomonori, Izumi
- Organizer
  HUPO 6th Annual World Congress
- Place of Presentation
  COEC Center, Seoul, Korea
- Year and Date
  2007-10-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390480

1. MAEKAWA Tsuyoshi (60034972)

# of Collaborated Projects : 8results

# of Collaborated Products : 7results
2. KASAOKA Shunji (90243667)

# of Collaborated Projects : 4results

# of Collaborated Products : 2results
3. Taoka Masato (60271160)

# of Collaborated Projects : 4results

# of Collaborated Products : 1results
4. MATSUZAKI Masunori (60116754)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. TSURUTA Ryosuke (30263768)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. KANEKO Tadashi (50362372)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. IKEDA Yasuhiro (00260349)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. YANO Masafumi (90294628)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. AOKI Hiroki (60322244)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. YAMAMOTO Takeshi (50363122)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. OGINO Keiki (70204104)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. OU Tatsuko (90294404)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. TAKIGAWA Tomoko (90403493)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. SASAKI Kenji (20116461)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. OUCHI Kazunobu (80351899)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. NAKAMURA Kazuyuki (90107748)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. FUJIOKA Takashi (50304473)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. SAKATA Yoshiyuki (10034927)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. FUJIOKA Aya (50464334)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
20. SHIMAMOTO Akira (70432713)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. ICHINOSE Akitada (10241689)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. SEIKI Motoharu (10154634)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
23. YANA Ikuo (70332583)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. ODA Yasutaka (40397998)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
25. 藤田基 (50380001)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
26. 橋口照人 (70250917)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
27. 小泉博靖 (40423389)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
28. OKADA Sae

# of Collaborated Projects : 1results

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29. 青山英和

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
30. 宮崎要介

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
31. 藤本静香

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

IZUMI Tomonori 泉 友則

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漏出細胞内タンパク質の新しい細胞外機能：受容体を共有する単球・内皮での役割と作用Principal InvestigatorOngoing

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シュードウリジン：新しいガンマーカーの探索Ongoing

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Extracellular function of intracellular proteins released from damaged tissue and bound to monocytes.Principal Investigator

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Comprehensive analysis of intracellular proteins on the cell surface for elucidation of their roles in tissue damage and repair.Principal Investigator

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Is a novel prognostic marker for post cardiac arrest brain injury beneficial or detrimental?Principal Investigator

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β_2-グリコプロテインIの生理機能及び抗リン脂質抗体を介した血栓症の分子機序Principal Investigator

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IZUMI Tomonori 泉友則