MATSUZAKI Masunori 松﨑益德

… Alternative Names

松崎益徳マツザキマスノリ

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Researcher Number	60116754
External Links
Affiliation (based on the past Project Information) *help	2012 – 2013: 山口大学, その他部局等, 名誉教授 2011: 山口大学, 医学(系)研究科(研究院), 教授 2007 – 2011: Yamaguchi University, 大学院・医学系研究科, 教授 2006: Yamaguchi University, Graduate School of Medicine, Professor, 大学院医学研究科, 教授 2006: Yamaguchi University, Graduate school of Medicine, Professor, 大学院医学系研究科, 教授 … More 2000 – 2005: 山口大学, 医学部, 教授 1992: 山口大学, 医学部・内科学第二講座, 教授 1991: 山口大学, 医学部, 助教授 1989 – 1990: 山口大学, 医学部, 講師 1986: 山口大, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine / Emergency medicine
Keywords	Principal Investigator 心筋症ハムスター / アデノウイルスベクター / 蛋白ホスファターゼ1 / 拡張型心筋症 / 慢性心不全 / アデノ随伴ウイルスベクター / 遺伝子導入 / protein phosphatase 1β / リアノジン受容体 / 筋小胞体 … More / 心不全 / 経食道超音波断層法 / molecular therapy / calcium handling / sarcoplasmic reticulum / heart failure / gene delivery / RyRドメインペプチド / 高効率生体内心筋遺伝子導入 / Inhibitor-2 / 高効率生体内遺伝子導入 / ドメイン相関 / 分子標的療法 / カルシウムイオン / バイオテクノロジー / トランスレーショナルリサーチ / 生理学 / 循環器・高血圧 / 遺伝子 / High efficiency in vivo cardiac gene transfer / cardiomyopathic hamster / Aden associated virus vector / Adenovirus vector / protein phosphatase 1 / dilated cardiomyopathy / chronic hears failure / 高効率心筋遺伝子導入 / アデノ関連ウイルスベクター / 心房細動 / 左心耳内血栓 / 左心耳内血流 / 食道内超音波断層心エコー・ドプラー法 / RNAi干渉 / RNA干渉 / AAVベクター / B-type natriuretic peptide promoter / RNAi / gene therapy / adeno-associated virus vector / ryanodine receptor / protein phosphatase / calcium / longitudinal SR / junctional SR / shotgun proteomics / sarcoplasmic reticulum(SR) / 分化 / 心筋細胞 / 圧負荷 / 幹細胞 / gap junction / 細胞内カルシウム / Cx43 / NKX2.5 / 舌筋 / calcein / 心筋 / 組織幹細胞 / Ca放出能 / β遮断薬 / FK506結合蛋白 / 血管特性 / 粥状動脈硬化 / 家族性高コレステロ-ル血症 / 胸部大動脈 / 動脈硬化 / 高コレステロ-ル血症 … More Except Principal Investigator コネキシン / ギャップ結合 / connexin / gap junction / tachyarrhythmia / 興奮刺激伝播 / 頻脈性不整脈 / atrial fibrillation / Ca2+-ATPase / 心房細動 / 心不全 / レニン・アンジオテンシン・アルドステロン系 / electrical propagation / electrical coupling / rennin-angiotensin-aldosterone system / renin-angiotensin-aldosterone system / conduction property / レニン・アンジオテンシン系 / 心房細胞 / inositol trisphosphate receptor / ryanodine receptor / molecular biology / sarcoplasmic reticulum / Ca2+ regulatory protein / Ca^<2+>-ATPase / Ca^<2+>制御蛋白 / リアノジン受容体 / イノシトール3リン酸受容体 / リアノジソ受容体 / 分子生物学 / 心筋筋小胞体 / Ca2+制御蛋白 / 画像診断 / 動脈硬化 / 光干渉断層法 / 冠動脈ステント / 虚血性心疾患 / 心筋特異的ノックアウトマウス / Cカルシウム循環 / 心筋細胞 / カルシウム循環 / 筋小胞体 / protein phosphatase 1 beta isoform / アデノ随伴ウイルスベクター / BNP / protein phosphatase 1 beta / AAV9ベクター / RNAi / gene therapy / adeno-associated virus vector / protein phosphatase 1β / ナノフロー高速液体クロマトグラフ / 医師主導型臨床研究 / 蛋白質カタログ / 質量分析計 / 網羅的プロテオーム解析 / 治療 / 不整脈 / contractility / ischemia / microdialysis / catecholamine / preconditioning / adenosine / coronary circulation / 左室拡張期充満 / 僧帽弁血流 / 心筋梗塞 / 左心室圧 / 左心房圧 Less

Novel evaluation method using 3D OCT for safety of drug eluting stent
- Principal Investigator
  
  OKAMURA Takayuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Establishment of Molecular Therapy for Severe Heart Failure and Intractable Fetal ArrhythmiaPrincipal Investigator
- Principal Investigator
  
  MATSUZAKI Masunori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Development of novel therapeutic strategy for heart failure which targets aberrant phosphorylation status in the sarcoplasmic reticulum of failing hearts
- Principal Investigator
  
  IKEDA Yasuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
網羅的プロテオーム解析とプロテオームデータベース構築による救命救急傷病の病態解明
- Principal Investigator
  
  前川剛志
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Emergency medicine
- Research Institution
  Yamaguchi University
Exploration into the Development of New Therapy for Heart Failure by Modifying Sarcoplasmic Reticulum Nanodomain FunctionPrincipal Investigator
- Principal Investigator
  
  MATSUZAKI Masunori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Investigation for the new upstream treatment of arrhythmias targetinggap junction remodeling of cardiomyocyte
- Principal Investigator
  
  OHKUSA Tomoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Gap Junction Remodeling and Renin-Angiotensin-Aldosterone System
- Principal Investigator
  
  OHKUSA TOMOKO
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
組織幹細胞から心筋細胞への分化に必要な外的シグナルの解明Principal Investigator
- Principal Investigator
  
  松崎益徳
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Development of molecular therapy correcting abnormal intracellular Ca^<2+> regulation in chronic heart failurePrincipal Investigator
- Principal Investigator
  
  MATSUZAKI Masunori
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Analysis of Molecular Mechanisms Underlying the Initiation and Perpetuation of Tachyarrhythmias
- Principal Investigator
  
  OHKUSA Tomoko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Development of gene therapy for treatment of dilated cardiomyopathy and associated heart failurePrincipal Investigator
- Principal Investigator
  
  MATSUZAKI Masunori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
不全心筋細胞内Ca過負荷に対するβ遮断薬の効果に関する研究Principal Investigator
- Principal Investigator
  
  松崎益徳
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
Molecular Analysis of Atrila fibrillation - approach through Ca2+ regulatory proteins -
- Principal Investigator
  
  OHKUSA Tomoko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
マイクロダイアリシス法による虚血時心筋代謝産物の測定とその冠動脈微小循環への影響
- Principal Investigator
  
  尾崎正治
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
経食道超音波断層法による高脂血症患者の胸部大動脈壁性状と薬剤治療効果に関する研究Principal Investigator
- Principal Investigator
  
  松崎益徳
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
経食道超普波断層法による高脂血症患者の胸部大動脈壁性状と薬剤治療効果に関する研究Principal Investigator
- Principal Investigator
  
  松崎益徳
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
後負荷に伴う左房機能変化及び僧帽弁血流変化
- Principal Investigator
  
  松田泰雄
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
食道内超音波断層・ドプラー法による左房内血栓形成と左房内血流動態との関係についてPrincipal Investigator
- Principal Investigator
  
  松崎益徳
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University

All 2014 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book Patent

[Book] 糖尿病と心臓病基礎知識と実践患者管理Q & A(第II章糖尿病に合併する循環器疾患3心不全と糖尿病)2010
- Author(s)
  池田安宏, 松崎益徳
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21390241
[Book] 糖尿病と心臓病基礎知識と実践患者管理Q & A(第II章糖尿病に合併する循環器疾患3心不全と糖尿病)2010
- Author(s)
  池田安宏, 松崎益徳
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21590932
[Book] Regression of Abdominal Aortic Aneurysms through Pharmacologic Therapy2009
- Author(s)
  Yoshimura K, Aoki H, Ikeda Y, Furutani A, Hamano K, Matsuzaki M
- Publisher
  Springer, Advances in Understanding Aortic Diseases
- Data Source
  KAKENHI-PROJECT-21590932
[Book] 最新医学別冊新しい診断と治療のABC64心臓突然死(第2章病理・病態心不全と心臓突然死)2009
- Author(s)
  池田安宏, 松崎益徳
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-21590932
[Book] 最新医学別冊新しい診断と治療のABC64心臓突然死(第2章病理・病態心不全と心臓突然死)2009
- Author(s)
  池田安宏, 松崎益徳
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-21390241
[Book] Regression of Abdominal Aortic Aneurysms through Pharmacologic Therapy2009
- Author(s)
  Yoshimura K, Aoki H, Ikeda Y, Furutani A, Hamano K, Matsuzaki M
- Publisher
  Springer, Advances in Understanding Aortic Diseases
- Data Source
  KAKENHI-PROJECT-21390241
[Book] Oxford University Press2008
- Author(s)
  Ikeda Y, Yamamoto T, Yano M, Matsuzaki M.
- Publisher
  Heart Failure Pathophyiology in Supportive Care for Cardiac Patient
- Data Source
  KAKENHI-PROJECT-19209030
[Journal Article] – Four Years After Implantation With a Sirolimus-Eluting Stent –2014
- Author(s)
  Hiroki Tateishi, Takayuki Okamura, Jutaro Yamada, Tomoko Nao, Takao Maeda, Takamasa Oda, Takeshi Nakamura, Toshiro Miura, Masunori Matsuzaki, Masafumi Yano
- Journal Title
  
  Circ J
  
  Volume: 78 Issue: 3 Pages: 772-774
- DOI
  10.1253/circj.CJ-13-0709
- NAID
  130003382223
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591045
[Journal Article] Heart Failure-Inducible Gene Therapy Targeting Protein Phosphatase 1 Prevents Progressive Left Ventricular2012
- Author(s)
  Miyazaki Y, Ikeda Y, Shiraishi K, Fujimoto N. S., Aoyama H, Yoshimura K, Inui M, Hoshijima M, Kasahara H, Aoki H, and Matsuzaki. M
- Journal Title
  
  Remodeling PLoS ONE
  
  Volume: 7(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] Heart Failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling2012
- Author(s)
  Yosuke Miyazaki
- Journal Title
  
  PLOS ONE
  
  Volume: 7 Issue: 4 Pages: 35875-35875
- DOI
  10.1371/journal.pone.0035875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390241, KAKENHI-PROJECT-21590932, KAKENHI-PROJECT-22390050, KAKENHI-PROJECT-22659232, KAKENHI-PROJECT-24390334, KAKENHI-PROJECT-24659640
[Journal Article] Sirolimus eluting stent fracture detection by three-dimensional optical coherence tomography2012
- Author(s)
  Okamura T, Matsuzaki M.
- Journal Title
  
  Catheter Cardiovasc Interv
  
  Volume: 79 Issue: 4 Pages: 628-32
- DOI
  10.1002/ccd.23268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591045
[Journal Article] Isoform-Specific Roles of Protein Phosphatase 1 Catalytic Subunits in Sarcoplasmic Reticulum-Mediated Ca2+ Cycling2011
- Author(s)
  Aoyama H, Ikeda Y, Miyazaki Y, Yoshimura K, Nishino S, Yamamoto T, Yano M, Inui M, Aoki H, Matsuzaki M
- Journal Title
  
  Cardiovasc Res
  
  Volume: 89(1) Pages: 79-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] 特集II第74回日本循環器学会学術集会2011
- Author(s)
  池田安宏, 宮崎要介, 松崎益徳
- Journal Title
  
  4.拡張不全とリモデリングの分子機序不全心の収縮・拡張性を規定する細胞内リン酸化調節異常と治療標的循環器専門医,日本循環器学会
  
  Volume: 19(1) Pages: 73-79
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca channel release leading to catecholaminergic polymorphic ventricular tachycardia2011
- Author(s)
  Suetomi T, Yano M, Uchinoumi H, Fukuda M, Hino A, Ono M, Xu X, Tateishi H, Okuda S, Doi M, Kobayashi S, Ikeda Y, Yamamoto T, Ikemoto N, Matsuzaki M
- Journal Title
  
  Circulation
  
  Volume: 124(6) Pages: 682-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] わが国の慢性心不全治療におけるメインテートの効能追加のインパクト臨床のあゆみ2011
- Author(s)
  松崎益徳, 斎藤能彦, 池田安宏
- Journal Title
  
  田辺三菱製薬
  
  Volume: 89 Pages: 21-24
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] 慢性心不全治療ガイドライン2010の改訂ポイント循環器内科2011
- Author(s)
  池田安宏, 松崎益徳
- Journal Title
  
  科学評論社
  
  Volume: 70(1) Pages: 91-97
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] [ガイドラインに基づいた心不全の非薬物療法]トピックス慢性心不全治療ガイドライン2010年改訂版における改訂ポイントCARDIAC PRACTICE2011
- Author(s)
  松崎益徳, 池田安宏, 大草知子, 矢野雅文
- Journal Title
  
  メディカルレビュー社
  
  Volume: 22(1) Pages: 15-20
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] わが国の慢性心不全治療におけるメインテートの効能追加のインパクト臨床のあゆみ2011
- Author(s)
  松崎益徳, 斎藤能彦, 池田安宏
- Journal Title
  
  田辺三菱製薬
  
  Volume: 89 Pages: 21-24
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] 特集第74回日本循環器学会学術集会4.拡張不全とリモデリングの分子機序不全心の収縮・拡張性を規定する細胞内リン酸化調節異常と治療標的循環器専門医2011
- Author(s)
  池田安宏, 宮崎要介, 松崎益徳
- Journal Title
  
  日本循環器学会
  
  Volume: 19(1) Pages: 73-79
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] 慢性心不全治療ガイドライン2010の改訂ポイント循環器内科2011
- Author(s)
  池田安宏, 松崎益徳
- Journal Title
  
  科学評論社
  
  Volume: 70(1) Pages: 91-97
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] Three-dimensional optical coherence tomography assessment of coronary wire re-crossing position during bifurcation stenting.2011
- Author(s)
  Okamura T, Yamada J, Nao T, Suetomi T, Maeda T, Shiraishi K, Miura T, Matsuzaki M.
- Journal Title
  
  Eurointervention
  
  Volume: 7 Issue: 7 Pages: 886-887
- DOI
  10.4244/eijv7i7a138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591045
[Journal Article] Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca channel release leading to catecholaminergic polymorphic ventricular tachycardia2011
- Author(s)
  Suetomi T, Yano M, Uchinoumi H, Fukuda M, Hino A, Ono M, Xu X, Tateishi H, Okuda S, Doi M, Kobayashi S, Ikeda Y, Yamamoto T, Ikemoto N, Matsuzaki M
- Journal Title
  
  Circulation
  
  Volume: 124(6) Pages: 682-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] Tenascin-C is expressed in abdominal aortic aneurysm tissue with an active degradation process2011
- Author(s)
  Kimura T, Yoshimura K, Aoki H, Imanaka-Yoshida K, Yoshida T, Ikeda Y, Morikage N, Endo H, Hamano K, Imaizumi T, Hiroe M, Aonuma K, Matsuzaki M
- Journal Title
  
  Pathol Int
  
  Volume: 61(10) Pages: 559-564
- NAID
  10030721173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] ガイドラインに基づいた心不全の非薬物療法2011
- Author(s)
  松崎益徳, 池田安宏, 大草知子, 矢野雅文
- Journal Title
  
  トピックス慢性心不全治療ガイドライン2010年改訂版における改訂ポイントCARDIAC PRACTICE,メディカルレビュー社
  
  Volume: 22(1) Pages: 15-20
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] Lysyl oxidase resolves inflammation by reducing monocyte chemoattractant protein-1 in abdominal aortic aneurysm2010
- Author(s)
  Onoda M, Yoshimura K, Aoki H, Ikeda Y, Morikage N, Furutani A, Matsuzaki M, Hamano K
- Journal Title
  
  Atherosclerosis
  
  Volume: 208(2) Pages: 366-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] [心不全研究と臨床の最前線]心不全の最先端研究トピックス心不全に対する遺伝子治療研究-分子標的治療とそのターゲット医学のあゆみ2010
- Author(s)
  池田安宏, 宮崎要介, 松崎益徳
- Journal Title
  
  医歯薬出版
  
  Volume: 232(5) Pages: 626-632
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction2010
- Author(s)
  Xu X, Yano M, Uchinoumi H, Hino A, Suetomi T, Ono M, Tateishi H, Oda T, Okuda S, Doi M, Kobayashi S, Yamamoto T, Ikeda Y, Ikemoto N, Matsuzaki M
- Journal Title
  
  Biochem Biophys Res Commun. 2010 Apr 9
  
  Volume: 394(3) Pages: 660-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] Tongue Muscle-Derived Stem Cells Express Connexin 43 and Improve Cardiac Remodeling and Survival After Myocardial Infarction in Mice2010
- Author(s)
  Shibuya M, Miura T, Fukagawa Y, Akashi S, Oda T, Kawamura S, Ikeda Y, Matsuzaki M
- Journal Title
  
  Circ J. 2010 Jun
  
  Volume: 74(6) Pages: 1219-26
- NAID
  10026475010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction2010
- Author(s)
  Xu X, Yano M, Uchinoumi H, Hino A, Suetomi T, Ono M, Tateishi H, Oda T, Okuda S, Doi M, Kobayashi S, Yamamoto T, Ikeda Y, Ikemoto N, Matsuzaki M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 394(3) Pages: 660-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor2010
- Author(s)
  Uchinoumi H, Yano M, Suetomi T, Ono M, Xu X, Tateishi H, Oda T, Okuda S, Doi M, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, Ikemoto N, Matsuzaki M
- Journal Title
  
  Circ Res
  
  Volume: 106(8) Pages: 1413-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] 心不全研究と臨床の最前線2010
- Author(s)
  池田安宏, 宮崎要介, 松崎益徳
- Journal Title
  
  心不全の最先端研究トピックス心不全に対する遺伝子治療研究-分子標的治療とそのターゲット医学のあゆみ,医歯薬出版
  
  Volume: 232(5) Pages: 626-632
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor2010
- Author(s)
  Uchinoumi H, Yano M, Suetomi T, Ono M, Xu X, Tateishi H, Oda T, Okuda S, Doi M, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, Ikemoto N, Matsuzaki M
- Journal Title
  
  Circ Res. 2010 Apr 30
  
  Volume: 106(8) Pages: 1413-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] Isoform-Specific Roles of Protein Phosphatase 1 Catalytic Subunits in Sarcoplasmic Reticulum-Mediated Ca2+ Cycling2010
- Author(s)
  Aoyama H, Ikeda Y, Miyazaki Y, Yoshimura K, Nishino S, Yamamoto T, Yano M, Inui M, Aoki H, Matsuzaki M
- Journal Title
  
  Cardiovasc Res. 2011 Jan 1
  
  Volume: 89(1) Pages: 79-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] Ischemic pre-conditioning enhances the mobilization and recruitment of bone marrow stem cells to protect against ischemia/ reperfusion injury in the late phase2009
- Author(s)
  Kamota T, Li TS, Morikage N, Murakami M, Ohshima M, Kubo M, Kobayashi T, Mikamo A, Ikeda Y, Matsuzaki M, Hamano K
- Journal Title
  
  J Am Coll Cardiol
  
  Volume: 53(19) Pages: 1814-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] Dantrolene, a therapeutic agent for malignant hyperthermia2009
- Author(s)
  Kobayashi S, Yano M, Suetomi T, Ono M, Tateishi H, Mochizuki M, Xu X, Uchinoumi H, Okuda S, Yamamoto T, Koseki N, Kyushiki H, Ikemoto N, Matsuzaki M.
- Journal Title
  
  markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor. J Am Coll Cardiol 53(21)
  
  Pages: 1993-2005
- Data Source
  KAKENHI-PROJECT-19209030
[Journal Article] Lysyl oxidase resolves in flammation by reducing monocyte chemoat tractant protein-1 in abdominal aortic aneurysm2009
- Author(s)
  Onoda M, Yoshimura K, Aoki H, Ikeda Y, Morikage N, Furutani A, Matsuzaki M, Hamano K
- Journal Title
  
  Atherosclerosis. 2010 Feb
  
  Volume: 208(2) Pages: 366-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] Role of ryanodine receptor as a Ca(2+) regulatory center in normal and failing hearts2009
- Author(s)
  Yano M, Yamamoto T, Kobayashi S, Matsuzaki M.
- Journal Title
  
  J Cardiol 53(1)
  
  Pages: 1-7
- NAID
  10025182309
- Data Source
  KAKENHI-PROJECT-19209030
[Journal Article] 慢性心不全の治療の変遷と新しい分子標的治療法の開発日本医事新報2009
- Author(s)
  池田安宏, 松崎益徳
- Journal Title
  
  日本医事新報社
  
  Volume: 4449 Pages: 74-75
- Data Source
  KAKENHI-PROJECT-21590932
[Journal Article] 慢性心不全の治療の変遷と新しい分子標的治療法の開発日本医事新報2009
- Author(s)
  池田安宏, 松崎益徳
- Journal Title
  
  日本医事新報社
  
  Volume: 4449 Pages: 74-75
- Data Source
  KAKENHI-PROJECT-21390241
[Journal Article] Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca^<2+> leak in failing hearts2008
- Author(s)
  Tateishi H, Yano M, Mochizuki M, Suetomi T, Ono M, Xu X, Uchinoumi H, Okuda S, Oda T, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, Ikemoto N, Matsuzaki M.
- Journal Title
  
  Cardiovasc Res
- Data Source
  KAKENHI-PROJECT-19209030
[Journal Article] Altered expression of connexin43contributes to the arrhythomogenicsubstrate during the development of heartfailure in cardiomyopathic hamster2008
- Author(s)
  Sato T, Ohkusa T, Honjo H, Suzuki S,Yoshida M, Ishiguro YS, Nakagawa H,Yamazaki M, Yano M, Kodama I, Matsuzaki M
- Journal Title
  
  Am JPhysiol Heart Circ Physiol 294
  
  Pages: 174-1182
- Data Source
  KAKENHI-PROJECT-19590818
[Journal Article] Identification of target domains of the cardiac ryanodine receptor to correct channel disorder in failing hearts2008
- Author(s)
  Yamamoto T, Yano M, Xu X, Uchinoumi H, Tateishi H, Mochizuki M, Oda T, Kobayashi S, Ikemoto N, Matsuzaki M.
- Journal Title
  
  Circulation 117(6)(PubMed PMID : 18227387)
  
  Pages: 762-72
- Data Source
  KAKENHI-PROJECT-19209030
[Journal Article] Comparison of cell therapy and cytokine therapy for functional repair in ischemic and nonischemic heart failure2007
- Author(s)
  Li TS, Mikamo A, Takahashi M, Suzuki R, Ueda K, Ikeda Y, Matsuzaki M, Hamano K.
- Journal Title
  
  Cell Transplant 16(4)
  
  Pages: 365-74
- Data Source
  KAKENHI-PROJECT-19209030
[Journal Article] Scavenging FreeRadicals by Low-Dose Carvedilol PreventsRedox-Dependent Ca^<2+> Leak ViaStabilization of Ryanodine Receptor inHeart Failure2007
- Author(s)
  Mochizuki M,Yano M, Oda T, Tateishi H,Kobayashi S, Yamamoto T, Ikeda Y, OhkusaT, Ikemot N, Matsuzaki M.
- Journal Title
  
  J Am Coll Cardiol 49(16)
  
  Pages: 1772-1732
- Data Source
  KAKENHI-PROJECT-19590818
[Journal Article] Effects of aldosterone onCx43 gap junction expressionin neonatal rat cultured cardiomyocytes2007
- Author(s)
  Suzuki S, Ohkusa T, Sato T, Yoshida M,Yasui K, Miwa K, Lee JK, Yano M, Kodama I,Matsuzaki M
- Journal Title
  
  Circ J(in press)
- Data Source
  KAKENHI-PROJECT-19590818
[Journal Article] Progression of heart failure was suppressed by inhibition of apoptosis-signal regulating kinase2007
- Author(s)
  Hikoso M, Ikeda Y, Yamaguchi O, Takeda T, Higuchi Y, Hirotani S, Kashiwase K, Yamada M, Asahi M, Matsumura Y, Nishida K, Matsuzaki M, Hori M, Otsu K.
- Journal Title
  
  1(ASK-1) via transcoronary gene transferJ Am Coll Cardiol 50(5)(co-first author)
  
  Pages: 453-462
- Data Source
  KAKENHI-PROJECT-19209030
[Journal Article] Scavenging free radicals by low-dose carvedilol prevents redox-dependent Ca2+ leak via stabilization of ryanodine receptor in heart failure2007
- Author(s)
  Mochizuki M, Yano M, Oda T, Tateishi H, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, Ikemoto N, Matsuzaki M.
- Journal Title
  
  J Am Coll Cardiol 49(16)
  
  Pages: 1722-32
- Data Source
  KAKENHI-PROJECT-19209030
[Journal Article] Beneficial effects of thedual L- and T-type Ca2+ channel blockerefonidipine on cardiomyopathic hamster2007
- Author(s)
  Suzuki S, Ohkusa T, Ono K, Sato T,Yoshida M, Yano M, Takebayashi S,Matsuzaki M.
- Journal Title
  
  Circ J 71(12)
  
  Pages: 1970-1796
- Data Source
  KAKENHI-PROJECT-19590818
[Journal Article] High Ambient Pressure Produces Hypertrophy and Up-Regulates Cardiac Sarcoplasmic Reticulum Ca^<2+> Regulatory Proteins in Cultured Rat Cardiomyocytes.2006
- Author(s)
  Sato T, Ohkusa T, Suzuki S, Nao T, Yano M, Matsuzaki M.
- Journal Title
  
  Hypertension Research 29(12)
  
  Pages: 1013-1020
- NAID
  10018560890
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590738
[Journal Article] Altered intracellular Ca2+ handling in heart failure2005
- Author(s)
  Yano Masafumi, Yasuhiro Ikeda, Masunori Matsuzaki
- Journal Title
  
  J Clin Invest. 115
  
  Pages: 556-564
- Data Source
  KAKENHI-PROJECT-16209026
[Journal Article] Sorcin interacts with sarcoplasmic reticulum Ca2+-ATPase and modulates excitation-contraction coupling in the heart.2005
- Author(s)
  Matsumoto T, Hisamatsu Y, Ohkusa T, Inoue N, Sato T, Suzuki S, Ikeda Y, Matsuzaki M.
- Journal Title
  
  Basic Res Cardiol 100(3)
  
  Pages: 250-262
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590738
[Journal Article] Rapid Electrical Stimulation of Contraction Modulates Gap-Junction Protein in Neonatal Rat Cultured Cardiomyocytes : Involvement of Mitogen-Activated Protein Kinases and Effects of Angiotensin II-Receptor Antagonist.2004
- Author(s)
  Inoue N, Ohkusa T, Nao T, Lee JK, Matsumoto T, Hisamatsu Y, Satoh T, Yano M, Yasui K, Kodama I, Matsuzaki M
- Journal Title
  
  Journal of the American College of Cardiology 44
  
  Pages: 914-922
- NAID
  120001070018
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590753
[Journal Article] Down-regulation od sarcolipin mRNA expression in chronic atrial fibrillation2004
- Author(s)
  Uemura N, Ohkusa T, Hamano K, Nakagome M, Hori H, Shimizu M, Matsuzaki M, Mochizuki S, Manamisawa S, Ishikawa Y.
- Journal Title
  
  European Journal of Clinical Investigation 34
  
  Pages: 723-730
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590753
[Journal Article] Comparison of Expression of Connexin in Right Atrial Myocardium in Patients with Chronic Atrial Fibrillation -vs- Those in Sinus Rhythm.2003
- Author(s)
  Nao T, Ohkusa T, Hisamatsu Y, Inoue N, Matsumoto T, Yamada J, Shimizu A, Yoshiga Y, Yamagata T, Kobayashi K, Yano M, Hamano K, Matsuzaki M.
- Journal Title
  
  American Journal of Cardiology 91(6)
  
  Pages: 678-683
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590753
[Patent] ホスホランバン標的修飾RNAアプタマー2012
- Inventor(s)
  乾誠、池田安宏、松崎益徳, 他
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2012-028555
- Filing Date
  2012-02-13
- Data Source
  KAKENHI-PROJECT-21590932
[Patent] ホスホランバン標的修飾RNAアプタマー2012
- Inventor(s)
  乾誠, 池田安宏, 松崎益徳他
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2012-028555
- Filing Date
  2012-02-13
- Data Source
  KAKENHI-PROJECT-21590932
[Patent] ホスホランバン標的修飾RNAアプタマー2012
- Inventor(s)
  乾誠, 池田安宏, 松崎益徳, 他
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2012-028555
- Filing Date
  2012-02-13
- Data Source
  KAKENHI-PROJECT-21390241
[Patent] ホスホランバン標的修飾RNAアプタマー2012
- Inventor(s)
  乾誠、池田安宏、松崎益徳, 他
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2012-028555
- Filing Date
  2012-02-13
- Data Source
  KAKENHI-PROJECT-21390241
[Presentation] Novel Automatic Stent Strut Detection Technique for Rapid Three-dimensional Optical Coherence Tomography to Complex Stenting Procedure2012
- Author(s)
  T Okamura, T Maeda, J Yamada, T Nao, T Suetomi, M Yoshimura, A Hino, T Oda, T Nakashima, K Shiraishi, T Nakashima, T Nakamura, S Nishimura, T Miura, M Matsuzaki
- Organizer
  日本循環器学会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-23591045
[Presentation] Novel Automatic Stent Strut Detection Technique for Rapid Three-dimensional Optical Coherence Tomography to Complex Stenting Procedure2012
- Author(s)
  Okamura T, Maeda T, Yamada J, Nao T, Suetomi T, Yoshimura M, Hino A, Oda T, Nakashima T, Shiraishi K, Nakashima T, Nakamura T, Nishimura S, Miura T, Matsuzaki M.
- Organizer
  第76回日本循環器学会
- Place of Presentation
  福岡、福岡国際会議場
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-23591045
[Presentation] Three-Dimensional Optical Coherence Tomography Assessment of Strut Coverage after Everolimus-Eluting Stent Implantation2012
- Author(s)
  T Maeda, T Okamura, J Yamada, T Nao, M Yoshimura, T Suetomi, A Hino, T Oda, T Nakashima, K Shiraishi, T Nakashima, T Nakamura, S Nishimura, T Miura, M Matsuzaki
- Organizer
  米国心臓病学会
- Place of Presentation
  シカゴ（アメリカ）
- Data Source
  KAKENHI-PROJECT-23591045
[Presentation] Revision points and remaining issues to be solved in the updated guidelines for treatment of chronic heart failure2011
- Author(s)
  Ikeda Y, Ohkusa T, Yano M, Matsuzaki M
- Organizer
  The 15th Annual Scientific Meeting of the Japanese Heart Failure Society
- Place of Presentation
  Kagoshima, Kagoshima Prefectural Citizens Exchange Center
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] Revision points and remaining issues to be solved in the updated guidelines for treatment of chronic heart failure2011
- Author(s)
  Ikeda Y, Ohkusa T, Yano M, Matsuzaki M
- Organizer
  The 15th Annual Scientific Meeting of the Japanese Heart Failure Society
- Place of Presentation
  Kagoshima, Kagoshima Prefectural Citizens Exchange Center
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21390241
[Presentation] In vivo Heart failure inducible suppression of protein phosphatase 1b mitigates heart failure progression in cardiomyopathic mice2011
- Author(s)
  Miyazki Y, Ikeda Y, Shiraishi K, Aoki H, Matsuzaki M
- Organizer
  Basic Cardiovascular Sciences Annual Conference
- Place of Presentation
  New Orleans, U. S. A.
- Data Source
  KAKENHI-PROJECT-21390241
[Presentation] In vivo Heart failure inducible suppression of protein phosphatase 1b mitigates heart failure progression in cardiomyopathic mice2011
- Author(s)
  Miyazki Y, Ikeda Y, Shiraishi K, Aoki H, Matsuzaki M
- Organizer
  Basic Cardiovascular Sciences Annual Conference
- Place of Presentation
  New Orleans, U. S. A.
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] In vivo Heart failure inducible suppression of prote in phosphatase 1b mitigates heart failure progression in cardiomyopathic mice2011
- Author(s)
  Miyazki Y, Ikeda Y, Shiraishi K, Aoki H, Matsuzaki M
- Organizer
  Best poster award of subspeciality AHA annual scientific meeting
- Place of Presentation
  Orlando, U. S. A.
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] In vivo Heart failure inducible suppression of protein phosphatase 1b mitigates heart failure progression in cardiomyopathic mice2011
- Author(s)
  Miyazki Y, Ikeda Y, Shiraishi K, Aoki H, Matsuzaki M
- Organizer
  Best poster award of subspeciality AHA annual scientific meeting
- Place of Presentation
  Orlando, U. S. A.
- Data Source
  KAKENHI-PROJECT-21390241
[Presentation] Protein phosphatase 1 is critical to determine cardiac diastolic function in cardiomyopatic mice2010
- Author(s)
  Miyazaki Y, Ikeda Y, Aoyama H, Shiraishi K, Yoshimura K, Yano M, Aoki H, Matsuzaki M
- Organizer
  20th World Congress of the International Society for Heart Research
- Place of Presentation
  Kyoto, Kyoto Internatioal Conference Center
- Data Source
  KAKENHI-PROJECT-21390241
[Presentation] Protein phosphatase 1 is critical to determine cardiac diastolic function in cardiomyopatic mice2010
- Author(s)
  Miyazaki Y, Ikeda Y, Aoyama H, Shiraishi K, Yoshimura K, Yano M, Aoki H, Matsuzaki M
- Organizer
  20th World Congress of the International Society for Heart Research
- Place of Presentation
  Kyoto, Kyoto Internatioal Conference Center
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] In Vivo inducible suppression of phosphatase 1 ameliorates cardiac dysfunction in mouse cardiomyopathy2010
- Author(s)
  Miyazaki Y, Ikeda Y, Aoyama H, Shiraishi K, Yoshimura K, Yano M, Aoki H, Matsuzaki M
- Organizer
  19th International Conference of the Cardiovascular System Dynamics Society
- Place of Presentation
  Fukuoka, Centennial Hall Kyushu University School of Medicine
- Data Source
  KAKENHI-PROJECT-21390241
[Presentation] Mutation-linked defective domain interaction within the ryanodine receptor causes ca2+ leak leading to catecholaminergic polymorphic ventricular tachycardia2010
- Author(s)
  Suetomi T, Yano M, Fukuda M, Hino A, Ono M, Xu X, Susa T, Uchinoumi H, Oda T, Okuda S, Kobayashi S, Yamamoto T, Ikeda Y, Matsuzaki M
- Organizer
  83rd Scientific Session of American Heart Association
- Place of Presentation
  Chicago, U. S. A.
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] In Vivo inducible suppression of phosphatase 1 ameliorates cardiac dysfunction in mouse cardiomyopathy2010
- Author(s)
  Miyazaki Y, Ikeda Y, Aoyama H, Shiraishi K, Yoshimura K, Yano M, Aoki H, Matsuzaki M
- Organizer
  19th International Conference of the Cardiovascular System Dynamics Society
- Place of Presentation
  Fukuoka, Centennial Hall Kyushu University School of Medicine
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] Isoform-specific role of protein phosphatase catalyticsubunits in sarcoplasmic reticulum mediated ca2+ cycling in cardiomyocytes2010
- Author(s)
  Ikeda Y, Aoyama H, Miyazaki Y, Yoshimura K, Yamamoto T, Yano M, Matsuzaki M
- Organizer
  20th World Congress of the International Society for Heart Research
- Place of Presentation
  Kyoto, Kyoto Internatioal Conference Center
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] Isoform-specific role of prote in phosphatase 1 catalytic subunits in sarcoplasmic reticulum-mediated ca2+ cycling2010
- Author(s)
  Ikeda Y, Aoyama H, Miyazaki Y, Shiraishi K, Yoshimura K, Nishino S, Yamamoto T, Yano M, Inui M, Aoki H, Matsuzaki M
- Organizer
  19th International Conference of the Cardiovascular System Dynamics Society
- Place of Presentation
  Fukuoka, Centennial Hall Kyushu University School of Medicine
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] Isoform-specific role of protein phosphatase 1 catalytic subunits in sarcoplasmic reticulum-mediated ca2+ cycling2010
- Author(s)
  Ikeda Y, Aoyama H, Miyazaki Y, Shiraishi K, Yoshimura K, Nishino S, Yamamoto T, Yano M, Inui M, Aoki H, Matsuzaki M
- Organizer
  19th International Conference of the Cardiovascular System Dynamics Society
- Place of Presentation
  Fukuoka, Centennial Hall Kyushu University School of Medicine
- Data Source
  KAKENHI-PROJECT-21390241
[Presentation] Isoform-specific role of protein phosphatase 1 catalyticsubunits in sarcoplasmic reticulum mediated ca2+ cycling in cardiomyocytes2010
- Author(s)
  Ikeda Y, Aoyama H, Miyazaki Y, Yoshimura K, Yamamoto T, Yano M, Matsuzaki M
- Organizer
  20th World Congress of the International Society for Heart Research
- Place of Presentation
  Kyoto, Kyoto Internatioal Conference Center
- Data Source
  KAKENHI-PROJECT-21390241
[Presentation] Abnormally TightDomain-Domain Interaction at MutationSite could be a Primary Cause ofCatecholaminergic PolymorphicVentricular Tachycardia2009
- Author(s)
  Takeshi Suetomi, Masafumi Yano, MakotoOno, Xiaojuan Xu, Hitoshi Uchinoumi,Hiroki Tateishi, Shinichi Okuda, MasahiroDoi, Shigeki Kobayashi, Takeshi Yamamoto,Yasuhiro Ikeda, Tomoko Ohkusa, MasunoriMatsuzaki
- Organizer
  The 73rd AnnualScientific Meeting of The JapaneseCirculation Society
- Place of Presentation
  Osaka
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Mutation-linked channel disorder in catecholaminergic polymorphic ventricular tachycardia(CPVT) is caused by abnormally tight domain-domain interaction in RyR22009
- Author(s)
  Suetomi T, Yano M, Hino A, Ono M, Xu X, Susa T, Uchinoumi H, Oda T, Doi M, Okuda S, Kobayashi S, Ikeda Y, Yamamoto T, Matsuzaki M
- Organizer
  82nd Scientific Session of American Heart Association
- Place of Presentation
  Orlando, U. S. A.
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] Changesof Adhesion Junctions Precede the GapJunction Remodeling during theDevelopment of Heart Failure2009
- Author(s)
  Masaaki Yoshida, Tomoko Ohkusa, TakashiSatoh, Shinsuke Suzuki, Genzou Takemura,Itsuo Kodama, Masunori Matsuzaki
- Organizer
  The 73rdAnnual Scientific Meeting of The JapaneseCirculation Society
- Place of Presentation
  Osaka
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Tenascin-c has a protective role during the development of abdominal aortic aneurysm2009
- Author(s)
  Kimura T, Yoshimura K, Aoki H, Ikeda Y, Imanaka-Yoshida K, Yoshida T, Hamano K, Hiroe M, Aonuma K, Matsuzaki M
- Organizer
  82nd Scientific Session of American Heart Association
- Place of Presentation
  Orlando, U. S. A.
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] Defective Inter-domain Interaction mayCause Spontaneous Ca^<2+> Release via ReducedAffinity of Calmodulin Binding to RyR2 inFailing Hearts Failing Hearts2009
- Author(s)
  Makoto Ono, Masafumi Yano, TakeshiSuetomi, Xiaojuan Xu, Hitoshi Uchinoumi,Shinichi Okuda, Masahiro Doi, ShigekiKobayashi, Takeshi Yamamoto, YasuhiroIkeda, Tomoko Ohkusa, Masunori Matsuzaki,
- Organizer
  The 73rd Annual ScientificMeeting of The Japanese CirculationSociety
- Place of Presentation
  Osaka
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Decreased affinity of calmodulin to RyR2 may be a sauce mechanism of leaky channel in CPVT-associated mutation2009
- Author(s)
  Xu X, Yano M, Hino A, Suetomi T, Ono M, Uchinoumi H, Oda T, Doi M, Okuda S, Kobayashi S, Ikeda Y, Yamamoto T, Ohkusa T, Matsuzaki M
- Organizer
  82nd Scientific Session of American Heart Association
- Place of Presentation
  Orlando, U. S. A.
- Data Source
  KAKENHI-PROJECT-21590932
[Presentation] Aldosterone Modulated Gap JunctionRemodeling through MineralocorticoidReceptor2008
- Author(s)
  Shinsuke Suzuki, Tomoko Ohkusa, TakashiSatoh, Masa-aki Yoshida, Kenji Yasui,Kieko Miwa Jong-kook Lee, Itsuo Kodama,Masafumi Yano, Masunori Matsuzaki
- Organizer
  The 72nd Annual ScientificMeeting of the Japanese CirculationSociety
- Place of Presentation
  Fukuoka
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Abstract 5322 : Mutation-Linked, Defective Inter-Domain Interaction within the Cardiac Ryanodine Receptor as a Critical Cause of2008
- Author(s)
  Uchinoumi H, Yano M, Suetomi T, Xu Z, Ono M, Tateishi H, Okuda S, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, and Matsuzaki M
- Organizer
  Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) Circulation
- Place of Presentation
  New Orleans、USA(118 : S_526-b)
- Data Source
  KAKENHI-PROJECT-19209030
[Presentation] 慢性心不全患者における酸化ストレスマーカー : 尿8-hydroxy-2-deoxyguanosine(8-OHdG)の有用性について2008
- Author(s)
  小林茂樹,須佐建央,河村修二,田中健雄,伊藤真一,吉賀康裕,岡村誉之,大草知子,矢野雅文,藤井崇史,松崎益徳
- Organizer
  第105 回日本内科学会総会・講演会
- Place of Presentation
  東京
- Year and Date
  2008-04-11
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Abstract 1355 : The Vascular Smooth Muscle Cell-Autonomous Role of Id2 in Phenotypic Modulation In Vitro And2008
- Author(s)
  Aoki H, Yoshimura K, Ikeda Y, and Matsuzaki M
- Organizer
  Atherogenesis In Vivo Circulation
- Place of Presentation
  New Orleans、USA(118 : S_312-a)
- Data Source
  KAKENHI-PROJECT-19209030
[Presentation] Mutation-Linked, DefectiveInter-Domain Interaction within theCardiac Ryanodine Receptor as a CriticalCause of Catecholaminergic PolymorphicVentricular Tachycardia (CPVT)2008
- Author(s)
  Hitoshi Uchinoumi, Masafumi Yano,Takeshi Suetomi, Xiaojuan Xu, Makoto Ono,Hiroki Tateishi, Shinichi Okuda, ShigekiKobayashi, Takeshi Yamamoto, YasuhiroIkeda, Tomoko Ohkusa, Masunori Matsuzaki
- Organizer
  Scientific Sessions 2008 of American HeartAssociation
- Place of Presentation
  New Orleans
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] 不整脈発生気質としての細胞間接着構成タンパク異状モデル動物での検討2008
- Author(s)
  吉田雅昭,大草知子,竹村元三,松崎益徳
- Organizer
  第93回日本循環器学会中国地方会
- Place of Presentation
  広島
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Abstract 427 : c-Jun N-terminal Kinase 2 Translates Mechanical Stress to2008
- Author(s)
  Yoshimura K, Aoki H, Kimura K, Ikeda Y, Aoyama H, Miyazaki Y, Morikage N, Furutani A, Hamano H, and Matsuzaki M
- Organizer
  Inflammatory Signal in Macrophages and Promotes Progression of Abdominal Aortic Aneurysm In Vivo Circulation
- Place of Presentation
  New Orleans、USA(118 : S_303-b)
- Data Source
  KAKENHI-PROJECT-19209030
[Presentation] Decreased Affinity of CalmodulinBinding to RyR2 May Cause Leaky Channel inCPVT-Associated Mutation : Insight fromRyR^<2R2474s/+> Knock-In Mouse Model2008
- Author(s)
  Xiaojuan Xu, Masafumi Yano, TakeshiSuetomi, Makoto Ono, Hitoshi Uchinoumi,Hiroki Tateishi, Shinichi Okuda, ShigekiKobayashi, Takeshi Yamamoto, YasuhiroIkeda, Tomoko Ohkusa, Masunori Matsuzaki
- Organizer
  Scientific Sessions 2008 of American Heart Association
- Place of Presentation
  New Orleans
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Abstract 5289 : Abnormally Tight Domain-Domain Interaction at Mutation Site Could be a Primary Cause of Catecholaminergic Polymorphic Ventricular Tachycardia : Insight from RyR2^<S2246L/+> Knock-In Mouse2008
- Author(s)
  Suetomi T, Yano M, Xu X, Ono M, Uchinoumi H, Tateishi H, Okuda S, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, and Matsuzaki M
- Organizer
  Model Circulation
- Place of Presentation
  New Orleans、USA(118 : S_520-b)
- Data Source
  KAKENHI-PROJECT-19209030
[Presentation] Abstract 5251 : Defective Inter-domain Interaction May Cause Spontaneous Ca^<2+> Release Via2008
- Author(s)
  Ono M, Yano M, Suetomi T, Xu X, Uchinoumi H, Tateishi H, Okuda S, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, and Matsuzaki M
- Organizer
  Reduced Affinity of Calmodulin Binding to RyR2 in Failing Hearts Circulation
- Place of Presentation
  New Orleans、USA(118 : S_513-d-514S_ -d)
- Data Source
  KAKENHI-PROJECT-19209030
[Presentation] Abnormally Tight Domain-DomainInteraction at Mutation Site Could be aPrimary Cause of CatecholaminergicPolymorphic Ventricular Tachycardia : Insight from RyR2 S2246L/+Knock-In MouseModel2008
- Author(s)
  Takeshi Suetomi, Masafumi Yano,Xiaojuan Xu, Makoto Ono, Hitoshi Uchinoumi,Hiroki Tateishi, Shinichi Okuda, ShigekiKobayashi, Takeshi Yamamoto, YasuhiroIkeda, Tomoko Ohkusa, Masunori Matsuzaki
- Organizer
  Scientific Sessions 2008 ofAmerican Heart Association
- Place of Presentation
  New Orleans
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Abstract 5303 : Decreased Affinity of Calmodulin Binding to RyR2 May Cause Leaky Channel in CPVT-Associated Mutation : Insight from RyR2^<R2474s/+> Knock-In Mouse Model2008
- Author(s)
  Xu X, Yano M, Suetomi T, Ono M, Uchinoumi H, Tateishi H, Okuda S, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, and Matsuzaki M
- Organizer
  Circulation
- Place of Presentation
  New Orleans、USA(118 : S_523-a)
- Data Source
  KAKENHI-PROJECT-19209030
[Presentation] Urinary8-Hydroxy-2' -Deoxyguanosine LevelReflects Symptomatic Status and Severityof Systolic Dysfunction in Patients withChronic Heart Failure2008
- Author(s)
  Takehisa Susa, Shigeki Kobayashi, ShujiKawamura, Takeo Tanaka, Shinichi Itoh,Yasuhiro Yoshiga, Takayuki Okamura,Tomoko Ohkusa, Masafumi Yano, TakashiFujii, Masunori Matsuzaki
- Organizer
  The 72nd AnnualScientific Meeting of the JapaneseCirculation Society
- Place of Presentation
  Fukuoka
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Abstract 1533 : Protein Phosphatase 1 Beta is Most Abundan2008
- Author(s)
  Aoyama H, Ikeda Y, Miyazaki Y, Ono M, Yoshimura K, Yamamoto T, Aoki H, Inui M, and Matsuzaki M
- Organizer
  Isoform in the Longitudinal Sarcoplasmic Reticulum and Regulates Phospholamban Phosphorylation in Cardiomyocytes Circulation
- Place of Presentation
  New Orleans、USA(118 : S_345-c-346S_-c)
- Data Source
  KAKENHI-PROJECT-19209030
[Presentation] Defective Inter-domain Interaction MayCause Spontaneous Ca^<2+> Release Via ReducedAffinity of Calmodulin Binding to RyR2 inFailing Hearts2008
- Author(s)
  Makoto Ono, Masafumi Yano, TakeshiSuetomi, Xiaojuan Xu, Hitoshi Uchinoumi,Hiroki Tateishi, Shinichi Okuda, ShigekiKobayashi, Takeshi Yamamoto, YasuhiroIkeda, Tomoko Ohkusa, Masunori Matsuzaki
- Organizer
  Scientific Sessions 2008of American Heart Association
- Place of Presentation
  New Orleans
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] カテコラミン誘発性心室頻拍(CPVT)の発生機序としてのリアノジン受容体機能異常2007
- Author(s)
  内海仁志, 矢野雅文, 大野誠, 徐暁娟, 立石裕樹, 小林茂樹, 山本健, 大草知子, 池田安宏, 松崎益徳
- Organizer
  第91 回日本循環器学会中国地方会
- Place of Presentation
  米子
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] DefectiveDomain-Domain Interaction BetweenC-terminal and Central Regions ofRyanodine Receptor as a Critical Cause ofDiastolic Ca^<2+> Spark in CanineCardiomyocytes2007
- Author(s)
  Hiroki Tateishi, 、Masafumi Yano, MakotoOhno, Xiaojuan Xu, Hitoshi Uchinoumi,Mamoru Mochizuki, Shigeki Kobayashi,Takeshi Yamamoto, Yasuhiro Ikeda, TomokoOhkusa, Masunori Matsuzaki
- Organizer
  The 11th Annual ScientificMeeting of the Japanese Heart FailureSociety
- Place of Presentation
  Chiba
- Year and Date
  2007-09-09
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] T 型Ca^<2+>チャネルは心室筋細胞のアルドステロンによるギャップ結合リモデリングを制御する2007
- Author(s)
  鈴木慎介, 大草知子, 佐藤孝志, 吉田雅昭, 安井健二, 李鐘国, 三輪佳子, 児玉逸雄, 松崎益徳
- Organizer
  第24回日本心電学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Gap Junction Remodeling Caused byAldosterone is Modulated by Ca^<2+> ChannelActivity2007
- Author(s)
  Shinsuke Suzuki, Tomoko Ohkusa, TakashiSato, Keiko Miwa,Jong-Kook Lee, KenjiYasui, Itsuo Kodama, Masunori Matsuzaki
- Organizer
  The 11th Annual Scientific Meeting of theJapanese Heart Failure Society
- Place of Presentation
  Chiba
- Year and Date
  2007-09-09
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] アルドステロンの心筋細胞ギャップ結合リモデリングへの影響2007
- Author(s)
  鈴木慎介, 大草知子, 佐藤孝志, 三輪佳子, 李鐘国, 安井健二, 児玉逸雄, 松崎益徳
- Organizer
  第91回日本循環器学会中国地方会
- Place of Presentation
  米子
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] The Role of AnserineDuring the Development of Heart Failure inCardiomyopathic Hamster2007
- Author(s)
  Shinsuke Suzuki, Tomoko Ohkusa, TakashiSato, Fumiyo Ohya, Yoshiharu Matahira,Masunori Matsuzaki
- Organizer
  he 11th Annual Scientific Meeting of theJapanese Heart Failure Society
- Place of Presentation
  Chiba
- Year and Date
  2007-09-09
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] SpontaneousCa^2+ Sparks Through Mutated RyanodineReceptor as a Critical Cause ofCatecholaminergic PolymorphicVentricular Tachycardia2007
- Author(s)
  Hitoshi Uchinoumi, Masafumi Yano,Makoto Ohno, Xiaojuan Xu, Hiroki Tateishi,Mamoru Mochizuki, Shigeki Kobayashi,Takeshi Yamamoto, Yasuhiro Ikeda, TomokoOhkusa, Masunori Matsuzaki
- Organizer
  The 11th AnnualScientific Meeting of the Japanese HeartFailure Society
- Place of Presentation
  Chiba
- Year and Date
  2007-09-09
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] 学術諮問委員会提言シンポジウム「レニン・アンジオテンシン・アルドステロン系のギャップ結合リモデリングへの関与とupstream 治療について」2007
- Author(s)
  大草知子, 李鐘国, 安井健二, 児玉逸雄, 松崎益徳
- Organizer
  第24回日本心電学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Urinary 8-Hydroxy-2'-DeoxyguanosineLevel Reflects Symptomatic Status andSeverity of Systolic Dysfunction inPatients with Chronic Heart Failure2007
- Author(s)
  Takehisa Susa, Shigeki Kobayashi, SyujiKawamura, Shinichi Itoh, Takeo Tanaka,Yasuhiro Yoshiga, Tsuyoshi Ueyama,Takayuki Okamura, Tomoko Ohkusa, MasafumiYano, Takashi Fujii, Masunori Matsuzaki
- Organizer
  Scientific Sessions 2007 of American HeartAssociation
- Place of Presentation
  Orland
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19590818
[Presentation] Young Investigator's Award forInternational Students Finalists Lecture「Decreased affinity of calmodulinbinding to RyR2 may cause leaky channel inCPVT-associated mutation : Insight fromRyR2^<R2474S/+> Knock-in mouse model」2007
- Author(s)
  Xiaojuan Xu, Masafumi Yano, TakeshiSuetomi, Makoto Ono, Hitoshi Uchinoumi,Hiroki Tateishi, Shinichi Okuda, ShigekiKobayashi, Takeshi Yamamoto, YasuhiroIkeda, Tomoko Ohkusa, Masunori Matsuzaki
- Organizer
  The 73rd Annual Scientific Meeting of The Japanese Circulation Society
- Place of Presentation
  Osaka
- Year and Date
  2007-03-20
- Data Source
  KAKENHI-PROJECT-19590818

1. YANO Masafumi (90294628)

# of Collaborated Projects: 8 results

# of Collaborated Products: 36 results
2. OHKUSA Tomoko (00294629)

# of Collaborated Projects: 6 results

# of Collaborated Products: 30 results
3. IKEDA Yasuhiro (00260349)

# of Collaborated Projects: 6 results

# of Collaborated Products: 63 results
4. AOKI Hiroki (60322244)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. YAMAMOTO Takeshi (50363122)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
6. 楠川禮造 (10112228)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 青山英和

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 宮崎要介

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
9. IZUMI Tomonori (00261694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. MAEKAWA Tsuyoshi (60034972)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 片山和裕 (20204430)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 阿武義人 (00159542)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 三浦俊郎 (00243634)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 白石宏造

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 西野静香

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. UEYAMA Tsuyoshi (60380010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OKAMURA Takayuki (70380011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
18. KIMURA Yoshihiro (90301308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 松田泰雄 (70127786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 尾崎正治 (40136180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 笠岡俊志 (90243667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 鶴田良介 (30263768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 藤田基 (50380001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 金子唯 (50362372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 河村修二 (10380007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 塔間陽一 (70188712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 森谷浩四郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 田中伸明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 藤本静香

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 前田敏明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MATSUZAKI Masunori 松﨑 益德

松崎 益徳 マツザキ マスノリ

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Establishment of Molecular Therapy for Severe Heart Failure and Intractable Fetal ArrhythmiaPrincipal Investigator

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Exploration into the Development of New Therapy for Heart Failure by Modifying Sarcoplasmic Reticulum Nanodomain FunctionPrincipal Investigator

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組織幹細胞から心筋細胞への分化に必要な外的シグナルの解明Principal Investigator

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Development of molecular therapy correcting abnormal intracellular Ca^<2+> regulation in chronic heart failurePrincipal Investigator

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Development of gene therapy for treatment of dilated cardiomyopathy and associated heart failurePrincipal Investigator

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不全心筋細胞内Ca過負荷に対するβ遮断薬の効果に関する研究Principal Investigator

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MATSUZAKI Masunori 松﨑益德

松崎益徳マツザキマスノリ

[Journal Article] – Four Years After Implantation With a Sirolimus-Eluting Stent –2014