HIROSHI Nakanishi 中西博

… Alternative Names

中西博ナカニシヒロシ

NAKANISHI Hiroshi 中西博

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Researcher Number	20155774
Other IDs
External Links
Affiliation (Current)	2024: 安田女子大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2024: 安田女子大学, 薬学部, 教授 2018 – 2022: 安田女子大学, 薬学部, 教授 2016 – 2017: 九州大学, 歯学研究院, 教授 2012 – 2015: 九州大学, 歯学研究科(研究院), 教授 2014: 九州大学, 歯学研究院, 教授 … More 2012: 九州大学, 歯学研究院, 教授 2010: 九州大学, 歯学研究院, 教授 2007 – 2010: Kyushu University, Faculty of Dental Sciences, Professor 2008: 九州大学, 大学院歯学研究院, 教授 2006: 九州大学, 歯学研究科, 教授 2005 – 2006: 九州大学, 歯学研究院, 教授 2002 – 2004: 九州大学, 大学院・歯学研究院, 教授 2000: KYUSHU UNIVERSITY, GRADUATE SCHOOL OF DENTAL SCIENCE, PROFESSOR, 大学院・歯学研究院, 教授 1999: 九州大学, 歯学部, 助教授 1990 – 1998: 九州大学, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Functional basic dentistry / Basic Section 46010:Neuroscience-general-related / Medium-sized Section 57:Oral science and related fields / Biological Sciences / Biological Sciences Except Principal Investigator Functional basic dentistry / Functional basic dentistry / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Periodontology … More / Pain science / Psychiatric science / Conservative dentistry / Pathobiological dentistry/Dental radiology / Biological Sciences Less
Keywords	Principal Investigator ミクログリア / カテプシンE / カテプシンD / microglia / カテプシンS / 生体イメージング / ジンジバリス菌 / cathepsin D / ovalbumin / 老化 … More / IFN-γ / 神経障害性疼痛 / カテプシンB / NMDA受容体 / パッチクランプ / 培養上清 / 初代培養ミクログリア / 酵素活性 / IFN-beta / グリオーシス制御 / インターフェロン-beta / アストロサイト / インターフェロン-beta / トル様受容体3 / カテプシンH / 脳炎症 / 時計遺伝 / 網羅的遺伝子解析 / アルツハイマー病 / 炎症性反応 / 時計遺伝子 / 社会行動障害 / シナプス活動 / 概日リズム / シナプス強度 / スパイン密度 / 社会的行動 / 疼痛炎症 / 炎症疼痛 / M1/M2極性転換 / 分子スイッチ / プロテアーゼ反応 / カテプシン / P2Y6受容体 / 突起伸展 / 生体蛍光イメージング / lysosomal storage / nitric oxide / senescence / 未梢血管内注入 / GFPトランスジェニックマウス / 活性酸素種 / 単核貧食細胞 / 酵素補充 / リソソーム蓄積 / 単核貪食細胞 / conditioned medium / electrophysiology / NMDA receptor / macrophage / 電気生理 / マクロファージ / cathepsin D-deficient mice / invaliant chain / antigenic peptide / antigen presentation / cathepsin E / インターフェロン-γ / インターロイキン-2 / pepstatin A / カテプシン阻害剤 / カテプシンD欠損マウス / インバリアント鎖 / 抗原ペプチド / 抗原提示 / カテプシンンD / APOPTOSIS / BCL-2 / CASPASE-3 / PC12 CELL / PEPSTATIN A / LIPOPOLYSACCHARIDE / INTERFERON-gamma / MICROGLIA / CATHEPSIN E / ルミノール反応 / イムノブロット / ネクローシス / INF-γ / アポトーシス / Bcl-2 / PC12細胞 / カスパーゼ3 / ペプスタチンA / LPS / PHAGOCYTOSIS / LYSOSOME / AGING / TRIGEMINAL GANGLION / CATHEPSINS / ラット / 免疫電顕 / 免疫組織 / カテプシン群 / リソソーム系蛋白分解機構 / 三叉神経節神経細胞 / IFN- γ / Unc93b / TOLL様受容体と慢性疼痛 / Toll様受容体 / 歯科薬理学 / IL-18 / NF-κB / カスパーゼ-1 / IL-1β / T細胞 / オートファジー / モルヒネ / 慢性疼痛 / 炎症性疼痛 / クロモグラニンA / CD44 / ICAM-1 / RANKL / TGF-β1 / プロスタグランジンE2 / アジュバント関節炎 / リン質リポソーム / アルカリフォスファターゼ / 炎症生骨吸収 / ホスファチジルセリン / 破骨細胞 / 骨芽細胞 / 炎症性骨吸収 / リポソーム / 顔面神経 / 神経科学 / 軸索再生 / テネシンR / 軸索切断 / 顔面神経運動ニューロン / 長期増強 / パッチクランプ法 / グリシン / HPLC / グリシン結合部位 / 海馬CA1野ニューロン / 脳虚血 / GluR / リアルタイムRT-PCR / 細胞周期 / カイニン酸受容体 / dendritic beading / ATP / synaptic stripping / 神経伝達 / グルタミン酸 / 糖鎖 / エンドソーム / プロセッシング / 生合成 / DNA損傷 / 逆行性変性 / 顔面神経核 / 免疫組織化学 / 咬筋運動ニューロン / 分解調節 / basic FGF / アスパラギン酸プロテアーゼ … More Except Principal Investigator ミクログリア / Porphyromonas gingivalis / Arg-gingipain / カテプシンE / Lys-gingipain / 歯周病 / プロセシング / cytokine / カテプシン / 髄膜 / システインプロテアーゼ / 生合成 / 細胞内アスパラギン酸プロテアーゼ / グリア細胞 / 歯周病原性プロテアーゼ / アスパラギン酸プロテアーゼ / 胸腺細胞 / カテプシンD / free radical / Alzheimer / ISH / osteoclast / osteoprotegerin / RANK / RANKL / microglia / Bcl-2 / periodontal disease / 病原性プロテアーゼ / 歯周病原菌 / cysteine proteinases / 歯周病原性菌 / 歯肉溝滲出液 / 臨床評価法 / 歯周疾患 / 三叉神経節 / 炎症 / 三叉神経脊髄路核 / アルツハイマー病 / 老化 / 髄膜細胞 / アジュバント関節炎 / サイトカイン / 脳炎症 / 末梢炎症 / グラム陰性嫌気性細菌 / CHO細胞 / フレンド細胞 / 細胞内輸送 / 新規標的蛋白質 / 持続感染 / アクセサリー蛋白質 / ヘニパウイルス / 異常疼痛 / 口腔乾燥症 / 口腔生理学 / 歯学 / TRPV1 / 痛覚過敏 / 三叉神経節細胞 / 舌機械痛覚過敏 / トリップチャネルV4 / p38マップキナーゼ / 衛星細胞 / TRPV4 / p38 / 舌乾燥 / 舌痛 / 口腔乾燥 / 疫学調査 / 口腔健康 / アルツハイマー型認知症 / 全身炎症 / 認知機能 / 歯肉増殖 / 歯肉増殖症 / NMDA receotors / patch clamp / glial cells / inflammatory cytokines / leptomeninges / pain / アストロサイト / 下歯槽神経切断 / パッチクランプ / NMDA受容体 / パッチリランプ / 炎症性サイトカイン / 三叉神経痛 / beta amyloid / inflammation / microglio / bota-amilaid / フリーラジカル / βアミロイド / 破骨細胞 / 蛍光抗体法 / M-CSF / 歯根膜 / rat / periodontal tissue / caspase / PC12 cells / aging / neuronal death / intracellular aspartic proteinase / cathepsin E / 分化誘導 / 遺伝子導入 / 神経細胞 / 細胞死モデル / PC19細胞 / カスパーゼ / PC12細胞 / 神経細胞死 / novel inhibitors / porphyromonas gingivalis / gram-negative anaerobic bacterium / pathogen / periodontitis / 歯周病ワクチン / プロテアーゼインヒビター / 歯周病治療薬 / インヒビター / Agr-gingipain / 歯周菌 / 放線菌 / 新規阻害物質 / ジンジバリス菌 / 病原性細菌 / crysteine proteinase / virulence factors / oral anaerobic bacterium / 病原菌プロテアーゼ / 病原性発現機序 / 病原性因子 / Porphyromonase gingivalis / cathepsins / oral bacterium / proteinases / drug design / clinical parameter / 臨床評価法の確立 / 治療薬の開発 / primary structures / cloning / a virulence factor / periodontal pathogen / 機能と病態 / 蛋白質一次構造 / 遺伝子のクローニング / 病原性システインプロテアーゼ / Argingipain / 病原因子 / GINGIVAL CREVICULAR FLUID / MEDULLASIN / CATHEPSIN G / CATHEPSIN L / CATHEPSIN H / CATHEPSIN B / GINGIVITIS / PERIODONTITIS / プロテア-ゼ / カテプシンG / 顆粒球セリンプロテア-ゼ / 歯周組織の破壊 / 歯周組織破壊 / タンパク分解酵素 / P2Y12 / ATP / 舌神経 / ニューロン-グリア機能連関 / 延髄 / 神経損傷 / アストログリア / 異所性痛覚過敏 / 神経障害性疼痛 / 疼痛制御 / 三叉神経 / 神経科学 / 歯科基礎医学 / パラインフラメーション / TLR2 / pgLPS / IL-1 b / 歯周病菌LPS / PGE_2〓 / 密着結合蛋白質 / PGE_2 / 未着結合蛋白質 / PGE / カテプシンB / IL-1β / LPS / 密着結合タンパク質 / 髄膜-グリア / 病者行動 / バッテン病 / 神経系 / 品質管理 / エンドソーム・リソソーム系 / 神経変性疾患 / 蛋白質分解酵素 / エンドソーム・リソソーム / オートオファジー / 蛋白質分解 / タンパク質分解 / 生体防御 / オートファジー / ノックアウトマウス / リソソーム系 / エンドソーム / マクロファージ / ノックアウト / Prophyromonas gingivalis / 酵素欠損変異体 / 蛋白分解システム / 選別輸送機構 / チャイニーズハムスター卵巣細胞 / マウス白血病フレンド細胞 / 活性化機構 / カプテシンD Less

シダーウイルスをモデルとしたヘニパウイルス脳炎再発機序の解明と治療戦略への応用
- Principal Investigator
  
  小田康祐
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Yasuda Women's University
Regulatory mechanisms of the gliosis through TLR3/IFN-b signaling mediated by microgliaPrincipal Investigator
- Principal Investigator
  
  中西博
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Yasuda Women's University
Possible involvement of impaired intrinsic microglial clock in Periodontotis-associated exacerbation of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Nakanishi Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Yasuda Women's University
Comprehensive understanding of orofacial pain induced by dry mouth
- Principal Investigator
  
  IWATA Koichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University
ミクログリアのナイトライフの解析から捉える概日リズム障害発症メカニズムPrincipal Investigator
- Principal Investigator
  
  中西博
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Japan-China Joint Epidemiological Survey of Tibetan Elderly on Correlation between Oral Health and Cognitive Functions
- Principal Investigator
  
  Take Hiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
the unravelling of the role of cathepsin in gingival overgrowth
- Principal Investigator
  
  Yamashita Akiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Kyushu University
Analysis of Porphyromonas gingivalis-induced neuroinflammation by multi-photon imaging of microglia dynamicsPrincipal Investigator
- Principal Investigator
  
  Nakanishi Hiroshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Study on a microglial phenotypic switch with a focus on proteolytic responsePrincipal Investigator
- Principal Investigator
  
  Nakanishi Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Critical roles of the chromogranin A-cathepsin B system in a transition of acute pain to a chronic pain statePrincipal Investigator
- Principal Investigator
  
  HIROSHI Nakanishi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Mechanism of the rupture of meningeal-glia limitans during chronic Periodontitis
- Principal Investigator
  
  TAKE Hiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Involvement of endosomal Toll-like receptors in the development of neuropathic painPrincipal Investigator
- Principal Investigator
  
  HIROSHI Nakanishi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Involvement of glia-neuron functional interaction in intractable trigeminal neuropathic pain
- Principal Investigator
  
  IWATA Koichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University
Inhibition of bone destruction by phosphatidylserine-containing liposomes based on t he regulation of phagocytes functionsPrincipal Investigator
- Principal Investigator
  
  HIROSHI Nakanishi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Roles of cathepsin B in the production of IL-1β as a leptomenigal toxic factor during systemic inflammation
- Principal Investigator
  
  TAKE Hiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Age-dependent differential responses of glial cells and Leptomeningeas during systemic inflammation
- Principal Investigator
  
  SHINDOU Mayumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Okinawa Institute of Science and Technology
Association of leptomeningeal and glial cells in the persistent pain
- Principal Investigator
  
  TAKE Hiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Kyushu University
顔面神経-ミクログリアの細胞膜間に想定される軸索再生分子の探索Principal Investigator
- Principal Investigator
  
  中西博
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Research on the mechanism underlying the accelerated senescence in cathepsin D-deficient micePrincipal Investigator
- Principal Investigator
  
  NAKANISHI Hiroshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
ミクログリアによるグルタミン酸を介した神経伝達の動的制御Principal Investigator
- Principal Investigator
  
  中西博
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
The study on microglial activation by beta amyloid, peptides of Alzheimer's disease.
- Principal Investigator
  
  MONJI Akira
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  KYUSHU UNIVERSITY
Regulation of glutamatergic signalings by niacrophage/microgliaPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
In situ expression of RANKL, RANK, osteoprotegerin and cytokines in osteoclasts of rat periodontal tissue
- Principal Investigator
  
  YOSHIMINE Yoshito
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kyushu University
神経系におけるオートファジー・リソソームシステム
- Principal Investigator
  
  山本健二
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
エンドソーム・リソソーム系蛋白分解機構におけるカテプシンEの役割
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Involvement of cathepsin E in exogenous antigen processing in primary cultured microgliaPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Hiroshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
エンドソーム・リソソーム系蛋白分解機構におけるカテプシンEの役割
- Principal Investigator
  
  山本建二
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
カテプシンEの生合成と細胞内輸送および局在化機構の解析
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
歯周病原菌における蛋白分解システムとその異常の分子レベル解析
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
DESIGN AND DEVELOPMENT OF THERAPEUTIC AGENTS OF ADULT PERIODONTITIS THAT INHIBIT ARG-GINGIPAIN PRODUCED BY PORPHYROMONAS GINGIVALIS
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
Effect of overexpression of cathepsin E and Bcl-2 on neuronal death
- Principal Investigator
  
  HORI Nobuaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
EXPRESSION AND FUNCTION OF CATHEPSIN E IN ACTIVATED MICROGLIA FOLLOWING FACIAL NERVE INJURYPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Hiroshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
細胞内アスパラギン酸プロテアーゼの機能構造形成と細胞機能制御
- Principal Investigator
  
  山本健二
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
顔面神経切断に伴って増殖する反応性ミクログリアにおけるカテプシンEの性状解析Principal Investigator
- Principal Investigator
  
  中西博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
ROLES OF PATHOGENIC PROTEINASES IN PERIODONTAL DISEASE
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
DNA断片化ならびに細胞内プロテアーゼの動態を指標として逆行性神経変性の検討Principal Investigator
- Principal Investigator
  
  中西博
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
細胞内アスパラギン酸プロテアーゼの選別と輸送機構
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
アスパラギン酸プロテアーゼによる生理活性ペプチドの分解を介した三叉神経機能の調節Principal Investigator
- Principal Investigator
  
  中西博
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Structures and Functions of Periodontopathogenic Proteinases
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
DEVELOPMENT OF A NEW CLINICAL PARAMETER FOR ASSESSMENT OF PROGRESSIVE PERIODONTAL DIDEASE AND ITS THERAPEUTIC AND PREVENTIVE DRUGS
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUShU UNIVERSITY
PHYSIOLOGICAL AND PATHOLOGICAL STUDIES OF PROTEINASES IN THE RAT TRIGEMINAL GANGLION CELLSPrincipal Investigator
- Principal Investigator
  
  NAKANISHI Hiroshi Ph.D.
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
THE DEVELOPMENT OF A NEW CLINICAL PARAMETER FOR DIAGNOSIS OF PERIODONTAL DISEASES AND THE NEW DRUG DESIGN
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY

[Book] 口腔疾患と時間栄養学、「時間栄養学、;時計遺伝子、体内時計、食生活をつなぐ」2020
- Author(s)
  中西　博
- Total Pages
  244
- Publisher
  化学同人
- ISBN
  9784759820362
- Data Source
  KAKENHI-PROJECT-18K19650
[Book] 脳の半分を占めるグリア細胞:歯周病菌とミクログリアの不都合な関係 -アルツハイマー病治療のパラダイムシフト-2019
- Author(s)
  中西博、野中さおり
- Publisher
  実験医学増刊号
- ISBN
  9784758103824
- Data Source
  KAKENHI-PROJECT-18K19650
[Book] Microglia in Health and Disease2014
- Author(s)
  Rommy von Bernardi, Betsi Flores, Hiroshi Nakanishi
- Total Pages
  5
- Publisher
  Springer Science+Business Media New York
- Data Source
  KAKENHI-PROJECT-24390416
[Book] TNF-α signaling and cathepsin B, In: Tumor Necrosis Factor: Structure, Enzyme Regulation and Role in Health and Disease2013
- Author(s)
  Zhou Wu, Hiroshi Nakanishi
- Total Pages
  15
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-24659827
[Book] BK+ channels contribute to the cellular activation of microglia : a big channel in small glia, In: Glial Cells: Embryonic Development, Types/Functions and Role in Disease2013
- Author(s)
  Yoshinori Hayashi, Hiroshi Nakanishi
- Total Pages
  18
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-24659827
[Book] Microglia-aging and pain: Microglial cathepsin B-dependent IL-1β production, In: Interleukin-1: Genetics, Inflammatory Mechanisms and Role in Disease2013
- Author(s)
  Hiroshi Nakanishi, Zhou Wu
- Total Pages
  12
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-24659827
[Book] TNF-α signaling and cathepsin B, In : Tumor Necrosis Factor : Structure, Enzyme Regulation and Role in Health and Disease2013
- Author(s)
  Zhou Wu, Hiroshi Nakanishi
- Total Pages
  15
- Publisher
  Nova Science Publishers, Inc. New York
- Data Source
  KAKENHI-PROJECT-24390416
[Book] NMDAレセプターとミクログリア：ミクログリアのシナプス可塑性ならびにシナプス再編への関与2013
- Author(s)
  林　良憲、中西　博
- Total Pages
  26
- Publisher
  日本神経精神薬理学雑誌
- Data Source
  KAKENHI-PROJECT-24659827
[Book] Involvement of microglial cathepsin B in pro-interleukin-1β processing and persistent pain. In : inflammation, Chronic Disease and Cancer-Cell and Molecular Biology, Immunology and Clinic Base2013
- Author(s)
  Hiroshi Nakanishi, Zhou Wu
- Total Pages
  17
- Publisher
  Nova Science Publishers. Inc. New York
- Data Source
  KAKENHI-PROJECT-24390416
[Book] Interleukin-1: Genetics, Inflammatory Mechanisms and Role in Disease2013
- Author(s)
  Hiroshi Nakanishi and Zhou Wu
- Publisher
  Nova Science Publishers, Inc. New York
- Data Source
  KAKENHI-PROJECT-24592802
[Book] BK^+ channels contribute to the cellular activation of microglia : a big channel in small glia, In : Glial Cells : Embryonic Development, Types/Functions and Role in Disease2013
- Author(s)
  Hiroshi Nakanishi, Zhou Wu
- Total Pages
  12
- Publisher
  Nova Science Publishers, Inc., New Yor
- Data Source
  KAKENHI-PROJECT-24390416
[Book] Tumor Necrosis Factor: Structure, Enzyme Regulation and Role in Health and Disease2012
- Author(s)
  Zhou Wu, Hiroshi Nakanishi
- Publisher
  Nova Science Publishers, Inc. New York
- Data Source
  KAKENHI-PROJECT-24592802
[Book] Regulation of myeloid phagocytes by phosphatidylserine-containing liposomes : possible incolvement of prostaglandin E_2 and the potential terapeutic application.(Ed., GM Goodwin)(In : Prostaglandins : Biochemistry, Functions, Types and Roles)2010
- Author(s)
  Wu Z, Nakanishi H.
- Publisher
  Nova Science Publisher Inc., New York
- Data Source
  KAKENHI-PROJECT-20390472
[Book] Regulation of myeloid phagocytes by phosphatidylserine-containing liposomes : possible involvement of prostagrandin E_2 and the potential terapeutic application(Ed., G.M.Goodwin)(In : Prostaglandins : Biochemistry, Functions, Types and Roles)2010
- Author(s)
  Wu Z, Nakanishi H
- Publisher
  Nova Science Publisher, Inc., New York
- Data Source
  KAKENHI-PROJECT-20592174
[Book] Regulation of myeloid phagocytes by phosphatidylserine-containing liposomes : possible incolvement of prostaglandin E_2 and the potential terapeutic application. (Ed., GM Goodwin)(In : Prostaglandins : Biochemistry, Functions, Types and Roles)2010
- Author(s)
  Wu Z, Nakanishi H.
- Publisher
  Nova Science Publisher Inc., New York
- Data Source
  KAKENHI-PROJECT-20592174
[Book] Regulation of myeloid phagocytes by phosphatidylserine- containing liposomes : possible involvement of prostagrandin E_2 and the potential terapeutic application. In : Prostaglandins : Biochemistry, Functions, Types and Roles (Ed., G.M.Goodwin)2010
- Author(s)
  Wu Z, Nakanishi H
- Publisher
  Nova Science Publisher, Inc., New York
- Data Source
  KAKENHI-PROJECT-20390472
[Book] In Neuroimmunology Research Focus2007
- Author(s)
  Wu Z. and Nakanishi H.
- Publisher
  Nova Science Publishers Inc
- Data Source
  KAKENHI-PROJECT-19592171
[Book] Age-dependent differential activation profiles of glial cells by the leptomeninges during systemic inflammationNeuroimmunology Research Focus,(Broglio PV ed)2007
- Author(s)
  Wu Z. and Nakanishi H. (分担)
- Publisher
  Nova Science Publishers Inc.
- Data Source
  KAKENHI-PROJECT-19592171
[Book] Microglial Proteases:In Neural Protein Metabolism and Function.Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(LajthaA ed)2007
- Author(s)
  Nakanishi H.(分担)
- Publisher
  Kluwer Publishing Corporation
- Data Source
  KAKENHI-PROJECT-18613010
[Book] Handbook of Neurochemistry and Molecular Neurobiology2007
- Author(s)
  Nakanishi H.
- Publisher
  Kluwer Publishing Corporation
- Data Source
  KAKENHI-PROJECT-19592171
[Book] Microglial Proteases:In Neural Protein Metabolism & Function.Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(Lajtha A ed)2007
- Author(s)
  Nakanishi H.(分担)
- Publisher
  Kluwer Publishing Corporation
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Book] Microglial Proteases: In Neural Protein Metabolism and Function. Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(Lajtha A ed)2007
- Author(s)
  Nakanishi H. (分担)
- Publisher
  Kluwer Publishing Corporation
- Data Source
  KAKENHI-PROJECT-19592171
[Book] Microglial Proteases: Ineural Protein Metabolism and Function. Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(LajthaA ed)2007
- Author(s)
  Nakanishi, H.(分担)
- Publisher
  Kluwer Publishing Corporation
- Data Source
  KAKENHI-PROJECT-15082204
[Book] Microglial Proteases:In Neural Protein Metabolism and Function.Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(Lajtha A ed)2007
- Author(s)
  Nakanishi H.(分担)
- Publisher
  Kluwer Publishing Corporation
- Data Source
  KAKENHI-PROJECT-17390495
[Book] Microglial Proteases: In Neural Protein Metabolism & Function. Handbookof Neurochemistry and Molecular Neurobiology, vol.7 (Lajtha A ed)2007
- Author(s)
  Nakanishi H.(分担)
- Publisher
  Kluwer Publishing Corporation
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Book] Age-dependent differential activation profiles of glial cells by the leptomeninges during systemic inflammation: In Neuroimmmunology Research Focus,(Broglio PV ed)2007
- Author(s)
  Wu, Z・Nakanishi, H.(分担)
- Publisher
  Nova Science Publishers Inc.
- Data Source
  KAKENHI-PROJECT-15082204
[Book] Age-dependent differential activation profiles of glial cells by theleptomeninges during systemic inflammation: In NeuroimmunologyResearch Focus, (Broglio PV ed)2007
- Author(s)
  Wu Z. and Nakanishi H.(分担)
- Publisher
  Nova Science Publishers Inc
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Book] Age-dependent differential activation profiles of glial cells by theleptomeninges during systemic inflammation:In NeuroimmunologyResearch Focus, (Broglio PV ed)2007
- Author(s)
  Wu Z., Nakanishi H.(分担)
- Publisher
  Nova Science Publishers Inc
- Data Source
  KAKENHI-PROJECT-18613010
[Book] Age-dependent differential activation profiles of glial cells by the leptomeninges during systemic inflammation:In Neuroimmunology Research Focus, (Broglio PV ed)2007
- Author(s)
  Wu Z.and Nakanishi H.(分担)
- Publisher
  Nova Science Publishers Inc.
- Data Source
  KAKENHI-PROJECT-17390495
[Book] Proteases in the Brain(Proteases and synaptic activity)2005
- Author(s)
  Nakanishi, H.
- Publisher
  Kluwer Academic/Plenum Publisher
- Data Source
  KAKENHI-PROJECT-17390495
[Book] Protease in Biology and Disease, Chapter 12. Protease and Synaptic Activity pp. 303-〜3222005
- Author(s)
  Nakanishi, H.
- Total Pages
  383
- Publisher
  Kluwer Academic/Plenum Publisher
- Data Source
  KAKENHI-PROJECT-15082204
[Book] Proteases in the Brain (Proteases and synaptic activity)2005
- Author(s)
  Nakanishi, H.
- Total Pages
  383
- Publisher
  Kluwer Academic/Plenum Publisher
- Data Source
  KAKENHI-PROJECT-17659587
[Book] Proteases in the Brain(Proteases and synaptic activity)2005
- Author(s)
  Nakanishi, H.
- Total Pages
  383
- Publisher
  Kluwer Academic/Plenum Publisher
- Data Source
  KAKENHI-PROJECT-15082204
[Book] Kluwer Academic/Plenum Publishers2005
- Author(s)
  Nakanishi H.(分担)
- Publisher
  Proteases and synaptic activity.In:Proteases in Biology and Disease.Vol.3, (Eds:Lendeckel, U.and Hooper, N.)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Book] Cathepsin-dependent neuronal death pathways induced by methylmercury. (Ed. AP Clampet)(In : Methylmercury : Formation, Sources and Health Effects)
- Author(s)
  Nakanishi H, Wu Z.
- Publisher
  Nova Science Publisher Inc., New York (in press)
- Data Source
  KAKENHI-PROJECT-20592174
[Book] Cathepsin-dependent neuronal death pathways induced by methylmercury.(Ed. AP Clampet)(In : Methylmercury : Formation, Sources and Health Effects)
- Author(s)
  Nakanishi H, Wu Z.
- Publisher
  Nova Science Publisher Inc., New York, in press
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Targeting cellular gaps using Janus nanoparticles containing cationic polymers and surfactant lipids2023
- Author(s)
  Matsumoto Akihiro、Kitazawa Takeo、Hatori Yuta、Nakanishi Hiroshi、Watanabe Chie、Takashima Tomoya、Murakami Masahiro
- Journal Title
  
  Drug Discoveries & Therapeutics
  
  Volume: 17 Issue: 2 Pages: 104-113
- DOI
  10.5582/ddt.2022.01118
- ISSN
  1881-7831, 1881-784X
- Year and Date
  2023-04-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06383, KAKENHI-PROJECT-22K12828
[Journal Article] Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer’s disease2022
- Author(s)
  Xie Zhen、Meng Jie、Kong Wei、Wu Zhou、Lan Fei、Narengaowa、Hayashi Yoshinori、Yang Qinghu、Bai Zhantao、Nakanishi Hiroshi、Qing Hong、Ni Junjun
- Journal Title
  
  Aging Cell
  
  Volume: 21 Issue: 3
- DOI
  10.1111/acel.13565
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06383, KAKENHI-PROJECT-20K09896
[Journal Article] Secreted gingipains from Porphyromonas gingivalis induce increased permeability of human cerebral microvascular endotherial cells through intracellular degradation of tight junction proteins.2022
- Author(s)
  Nonaka S, Kadowaki T, Nakanishi H.
- Journal Title
  
  Neurochemistry International
  
  Volume: 154 Pages: 105282-105282
- DOI
  10.1016/j.neuint.2022.105282
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06383, KAKENHI-PROJECT-22K15287
[Journal Article] ATP13A2 modifies mitochondrial localization of overexpressed TOM20 to autolysosomal pathway2022
- Author(s)
  Hatori Yuta、Kanda Yukina、Nonaka Saori、Nakanishi Hiroshi、Kitazawa Takeo
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 11 Pages: e0276823-e0276823
- DOI
  10.1371/journal.pone.0276823
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06090, KAKENHI-PROJECT-21K06383
[Journal Article] Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer’s disease.2022
- Author(s)
  Xie Z , Meng J, Kong W, Wu Z, Lan F, Narengaowa, Hayashi Y, Qinghu Yang Q, Bai Z, Nakanishi H, Qing H, Ni J.
- Journal Title
  
  Aging Cell
  
  Volume: 21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06383
[Journal Article] Human β-Defensin 3 Inhibits Porphyromonas Gingivalis Lipopolysaccharide-Induced Oxidative and Inflammatory Responses of Microglia by Suppression of Cathepsins B and L2022
- Author(s)
  Inoue Erika、Minatozaki Shiyo、Katsuta Yui、Nonaka Saori、Nakanishi Hiroshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 23 Pages: 15099-15099
- DOI
  10.3390/ijms232315099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06383
[Journal Article] Microglial circadian clock regulation of microglial structural complexity, dendritic spine density and inflammatory response2021
- Author(s)
  Nakanishi Hiroshi、Ni Junjun、Nonaka Saori、Hayashi Yoshinori
- Journal Title
  
  Neurochemistry International
  
  Volume: 142 Pages: 104905-104905
- DOI
  10.1016/j.neuint.2020.104905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-18K19650
[Journal Article] Generation of CSF-1 independent ramified microglia from leptomeninges in vitro.2021
- Author(s)
  Tanaka J, Takahashi H, Yano H, Nakanishi H.
- Journal Title
  
  Cells
  
  Volume: 10 Pages: 24-24
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06383
[Journal Article] Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/INF-β signaling.2021
- Author(s)
  Ni J, Zhang X, Reinheckel T, Turk V, Nakanishi H.
- Journal Title
  
  J. Neuroinflammation
  
  Volume: 18 Issue: 1 Pages: 176-176
- DOI
  10.1186/s12974-021-02227-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06383
[Journal Article] Stem cells from human exfoliated deciduous teeth attenuate mechanical allodynia in mice through distinct from the siglec-9/MCP-1-mediated tissue-repairing mechanism2021
- Author(s)
  Hayashi Yoshinori、Kato Hiroki、Nonaka Kazuaki、Nakanishi Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 20053-20053
- DOI
  10.1038/s41598-021-99585-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-21K06383
[Journal Article] Microglial circadian clock regulation of microglial structural complexity, dendritic spine density and inflammatory response.2021
- Author(s)
  Nakanishi H., Ni J., Nonaka S., Hayashi Y.
- Journal Title
  
  Neurochemistry International
  
  Volume: 142 Pages: 104905-104905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06383
[Journal Article] Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury2021
- Author(s)
  Liu Yicong、Li Hui、Hu Jiangqi、Wu Zhou、Meng Jie、Hayashi Yoshinori、Nakanishi Hiroshi、Qing Hong、Ni Junjun
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 59 Issue: 1 Pages: 717-730
- DOI
  10.1007/s12035-021-02594-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-21K06383
[Journal Article] Generation of CSF1-Independent Ramified Microglia-Like Cells from Leptomeninges In Vitro2020
- Author(s)
  Tanaka J, Takahashi H, Yano H, Nakanishi H.
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 1 Pages: 24-37
- DOI
  10.3390/cells10010024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09333, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-20K21465
[Journal Article] Cathepsin regulation on microglial function.2020
- Author(s)
  Nakanishi H.
- Journal Title
  
  Biophys Biochim Acta Proteins Proteom.
  
  Volume: 1868 Issue: 9 Pages: 140465-140465
- DOI
  10.1016/j.bbapap.2020.140465
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] . Involvement of cathepsins in innate and adaptive immune responses in periodontitis.2020
- Author(s)
  Yan X, Wu Z, Wang B, Yu T, Hu Y, Wang S, Deng C, Zhao B, Nakanishi H, Zhang X.
- Journal Title
  
  Evid Based Complement Alternat Med.
  
  Volume: 2020 Issue: 1 Pages: 4517587-4517587
- DOI
  10.1155/2020/4517587
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] Neural stem cell?specific ITPA deficiency causes neural depolarization and epilepsy2020
- Author(s)
  Koga Yuichiro、Tsuchimoto Daisuke、Hayashi Yoshinori、Abolhassani Nona、Yoneshima Yasuto、Sakumi Kunihiko、Nakanishi Hiroshi、Toyokuni Shinya、Nakabeppu Yusaku
- Journal Title
  
  JCI Insight
  
  Volume: 5 Issue: 22
- DOI
  10.1172/jci.insight.140229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-18K06960, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H06276
[Journal Article] Secreted gingipains from Porphyromonas gingivalis induce microglial migration through endosomal signaling by protease-activated receptor 2.2020
- Author(s)
  Nonaka S, Nakanishi H.
- Journal Title
  
  Neurochem. Int.
  
  Volume: 140 Pages: 104840-104840
- DOI
  10.1016/j.neuint.2020.104840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] Microglial cathepsin B and Porphyromonas gingivalis gingipains as potential therapeutic targets for sporadic Alzheimer’s disease.2020
- Author(s)
  Nakanishi H., Nonaka S., Wu Z.
- Journal Title
  
  CNS & Neurol Disod. Drug Targets
  
  Volume: 19 Issue: 7 Pages: 495-502
- DOI
  10.2174/1871527319666200708125130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] Microglial cathepsin B as a key driver of inflammatory brain diseases and brain aging.2020
- Author(s)
  Nakanishi H.
- Journal Title
  
  Neural Regener Res
  
  Volume: 15 Issue: 1 Pages: 25-29
- DOI
  10.4103/1673-5374.264444
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] Induction of bone repair in rat calvarial defects using a combination of hydroxyapatite with phosphatidylserine liposomes2019
- Author(s)
  Hatakeyama J, Anan H, Hatakeyama Y, Matsumoto N, Takayama F, Wu Z, Matsuzaki E, Minakami M, Izumi T, Nakanishi H
- Journal Title
  
  Journal of Oral Science
  
  Volume: 61 Issue: 1 Pages: 111-118
- DOI
  10.2334/josnusd.17-0488
- NAID
  130007626633
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11032, KAKENHI-PROJECT-17K11728, KAKENHI-PROJECT-18K19650
[Journal Article] Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis.2019
- Author(s)
  Harada Y, Zhang J, Imari K, Yamasaki R, Ni J, Wu Z, Yamamoto K, Kira JI, Nakanishi H, Hayashi Y.
- Journal Title
  
  Pain
  
  Volume: 160 Issue: 9 Pages: 2050-2062
- DOI
  10.1097/j.pain.0000000000001596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16K11477
[Journal Article] Microglial clearance of focal apoptotic synapses.2019
- Author(s)
  Nonaka S, Nakanishi H.
- Journal Title
  
  Neurosci. Lett.
  
  Volume: 707 Pages: 134317-134317
- DOI
  10.1016/j.neulet.2019.134317
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] Mutations of beta-amyloid precursor protein after the consequence of Alzheimer's disease pathogenesis.2019
- Author(s)
  Li NM, Liu KF, Qiu YJ, Zhang HH, Nakanishi H, Qing H.
- Journal Title
  
  Neural Regen Res.
  
  Volume: 14 Issue: 4 Pages: 658-665
- DOI
  10.4103/1673-5374.247469
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain.2019
- Author(s)
  Ni J, Wu Z, Meng J, Saito T, Saido TC, Qing H, Nakanishi H.
- Journal Title
  
  J. Neuroinflamm.
  
  Volume: 16 Issue: 1 Pages: 173-173
- DOI
  10.1186/s12974-019-1562-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] Pterostilbene, an active component of the dragon’s blood extract, acts as an antiderpressant in adult rats.2019
- Author(s)
  Yang L, Ran Y, Quan Z, Wang R, Yang Q, Jia Q, Zhang H, Li Y, Peng Y, Liang J, Wang H, Nakanishi H, Deng Y, Qing H.
- Journal Title
  
  Psychopharmacology (Berl)
  
  Volume: 14 Issue: 4 Pages: 658-665
- DOI
  10.1007/s00213-018-5138-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] Manipulation of hippocampal CA3 firing via luminopsins modulates spatial and episodic short-term memory, especially working memory, but not long-term memory.2018
- Author(s)
  Song D, Yang Q, Lang Y, Wen Z, Xie Z, Zheng D, Yan T, Deng Y, Nakanishi H, Qing H
- Journal Title
  
  Neurobiol Learn Mem
  
  Volume: 155 Pages: 435-445
- DOI
  10.1016/j.nlm.2018.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19650
[Journal Article] Brazilian green propolis prevents cognitive decline into mild cognitive impairment in elderly people living at high altitude.2018
- Author(s)
  Zhu A, Wu Z, Zhong X, Ni J, Li Y, Meng J, Du C, Zhao X, Nakanishi H, Wu S
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: 63 Issue: 2 Pages: 551-560
- DOI
  10.3233/jad-170630
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-17K17093
[Journal Article] Ratanasampil Suppresses the Hypoxia-Related Inflammatory Responses by Inhibiting Oxidative Stress and NF-kB Activation in Microglia2018
- Author(s)
  Zhu Aiqin、Zhong Xin、Nian Wei、Wu Shizheng、Meng Jie、Ni Junjun、Hayashi Yoshinori、Wu Zhou、Nakanishi Hiroshi
- Journal Title
  
  Journal of Alzheimer’s Disease & Parkinsonism
  
  Volume: 08 Issue: 05 Pages: 451-451
- DOI
  10.4172/2161-0460.1000451
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-16K11478
[Journal Article] Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE through impairment toll-like receptor 3 cascade.2018
- Author(s)
  Okada R, Zhang Z, Harada Y, Wu Z, Nakanishi H
- Journal Title
  
  Inflamm Res
  
  Volume: 67 Pages: 371-374
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Journal Article] Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice.2018
- Author(s)
  Ni J, Wu Z, Stoka V, Meng J, Hayashi Y, Peters C, Qing H, Turk V, Nakanishi H. Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice
- Journal Title
  
  Aging Cell
  
  Volume: . Issue: 1
- DOI
  10.1111/acel.12856
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-17K17093
[Journal Article] 歯周病のアルツハイマー病における関与メカニズム2018
- Author(s)
  武　洲、中西　博
- Journal Title
  
  細胞・特集・口腔疾患のサイエンス・Current Topics in Oral Science
  
  Volume: 50 Pages: 45-49
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05848
[Journal Article] The critical role of IL-10 in the antineuroinflammatory and antioxidant effects of Rheum tanguticum on activated microglia.2018
- Author(s)
  Meng J, Ni J, Wu Z, Jiang M, Zhu A, Qing H, Nakanishi H.
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2018:1083596 Issue: 1 Pages: 1-12
- DOI
  10.1155/2018/1083596
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-16K11478, KAKENHI-PROJECT-17K17093
[Journal Article] A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain.2018
- Author(s)
  Fujii T, Yamasaki R, Iinuma K, Tsuchimoto D, Hayashi Y, Saitoh BY, Matsushita T, Kido MA, Aishima S, Nakanishi H, Nakabeppu Y, Kira JI.
- Journal Title
  
  Annals of Neurology
  
  Volume: 84 Issue: 2 Pages: 208-224
- DOI
  10.1002/ana.25279
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-17K19663, KAKENHI-PROJECT-17H01391
[Journal Article] Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE through impairment toll-like receptor 3 cascade.2018
- Author(s)
  Okada R, Zhang Z, Harada Y, Wu Z, Nakanishi H
- Journal Title
  
  Inflamm Res
  
  Volume: 67 Pages: 371-374
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Journal Article] Cathepsin S Is Involved in Th17 Differentiation Through the Upregulation of IL-6 by Activating PAR-2 after Systemic Exposure to Lipopolysaccharide from Porphyromonas gingivalis2017
- Author(s)
  Dekita Masato、Wu Zhou、Ni Junjun、Zhang Xinwen、Liu Yicong、Yan Xu、Nakanishi Hiroshi、Takahashi Ichiro
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 8 Pages: 1-13
- DOI
  10.3389/fphar.2017.00470
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice2017
- Author(s)
  Liu Yicong、Wu Zhou、Nakanishi Yurika、Ni Junjun、Hayashi Yoshinori、Takayama Fumiko、Zhou Yanmin、Kadawaki Tomoko、Nakanishi Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41598-017-12173-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-18K19650
[Journal Article] Boi-ogi-to (TJ-20), a Kampo Formula, Suppresses the Inflammatory Bone Destruction and the Expression of Cytokines in the Synovia of Ankle Joints of Adjuvant Arthritic Rats2017
- Author(s)
  Zhang Xinwen、Wu Zhou、Liu Yicong、Ni Junjun、Deng Chunfu、Zhao Baohong、Nakanishi Hiroshi、He Jing、Yan Xu
- Journal Title
  
  Evidence-Based Complementary and Alternative Medicine
  
  Volume: 2017 Issue: 1 Pages: 1-10
- DOI
  10.1155/2017/3679295
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] Infection of microglia with Porphyromonas gingivalis promotes cell migration and inflammatory response through the gingipain-mediated activation of protease-activated receptor-22017
- Author(s)
  Liu Y, WU Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadowaki T, Nakanishi H
- Journal Title
  
  Sci Rep
  
  Volume: ７:11759
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Journal Article] Overexpression of cathepsin E interferes with neuronal differentiation of P19 embryonal teratocarcinoma cells by degradation of N-cadherin.2017
- Author(s)
  Harada Y, Takayama F, Tanabe K, Ni J, Hayashu Y, Yamamoto K, Wu Z, Nakanishi H
- Journal Title
  
  Cell Mol Neurobiol
  
  Volume: 37 Pages: 437-443
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15684
[Journal Article] Dysfunction in diurnal synaptic responses and social behavior abnormalities in cathepsin S-deficient mice2017
- Author(s)
  Takayama Fumiko、Zhang Xinwen、Hayashi Yoshinori、Wu Zhou、Nakanishi Hiroshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 490 Issue: 2 Pages: 447-452
- DOI
  10.1016/j.bbrc.2017.06.061
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] The Neuroprotective Effects of Brazilian Green Propolis on Neurodegenerative Damage in Human Neuronal SH-SY5Y Cells2017
- Author(s)
  Ni Junjun、Wu Zhou、Meng Jie、Zhu Aiqin、Zhong Xin、Wu Shizheng、Nakanishi Hiroshi
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2017 Issue: 1 Pages: 1-13
- DOI
  10.1155/2017/7984327
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] Infection of microglia with Porphyromonas gingivalis promotes cell migration and inflammatory response through the gingipain-mediated activation of protease-activated receptor-22017
- Author(s)
  Liu Y, WU Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadowaki T, Nakanishi H
- Journal Title
  
  Sci Rep
  
  Volume: 7:11759
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Journal Article] Overexpression of cathepsin E interferes with neuronal differentiation of P19 embryonal teratocarcinoma cells by degradation of N-cadherin.2017
- Author(s)
  Harada Y, Takayama F, Tanabe K, Ni J, Hayashu Y, Yamamoto K, Wu Z, Nakanishi H
- Journal Title
  
  10.1007/s10571-016-0376-x.
  
  Volume: 37 Issue: 3 Pages: 437-443
- DOI
  10.1007/s10571-016-0376-x
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
[Journal Article] Cathepsin B plays a critical role in inducing Alzheimer’s disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice2017
- Author(s)
  Wu Zhou、Ni Junjun、Liu Yicong、Teeling Jessica L.、Takayama Fumiko、Collcutt Alex、Ibbett Paul、Nakanishi Hiroshi
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 65 Pages: 350-361
- DOI
  10.1016/j.bbi.2017.06.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
[Journal Article] An EP2 agonist facilitates NMDA-induced outward currents and inhibits dendritic beading through activation of BK channels in mouse cortical neurons.2016
- Author(s)
  Hayashi Y, Morinaga S, Liu X, Zhang J, Wu Z, Yokoyama T, Nakanishi H
- Journal Title
  
  Mediators Inflamm
  
  Volume: 2016 Pages: 5079597-5079597
- DOI
  10.1155/2016/5079597
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
[Journal Article] Cathepsin B regulates collagen expression by fibroblasts via prolonging TLR2/NF-kB activation.2016
- Author(s)
  Li X, Wu Z, Ni J, Liu Y, Meng J, Yu W, Nakanishi H, Zhou Y
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2016 Issue: 1 Pages: 7894247-7894247
- DOI
  10.1155/2016/7894247
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11478
[Journal Article] Nutrient, microglia aging, and brain aging.2016
- Author(s)
  Wu Z, Yu J, Zhu A, Nakanishi H
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2016 Issue: 1 Pages: 7498528-7498528
- DOI
  10.1155/2016/7498528
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11478
[Journal Article] Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system.2016
- Author(s)
  Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H
- Journal Title
  
  Sci Rep
  
  Volume: 6 Pages: 30006-30006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05015
[Journal Article] BK channels in microglia are required for2016
- Author(s)
  Yoshinori Hayashi, Saori Morinaga, Jing Zhang, Yasushi Satoh, Andrea Meredith, Takahiro Nakata, Zhou Wu, Shinichi Kohsaka, Kazuhide Inoue, Hiroshi Nakanishi
- Journal Title
  
  Nature communications
  
  Volume: 7 Issue: 1 Pages: 11697-11697
- DOI
  10.1038/ncomms11697
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04970, KAKENHI-PUBLICLY-16H01340, KAKENHI-PLANNED-25117009, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
[Journal Article] Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system.2016
- Author(s)
  Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 30006-30006
- DOI
  10.1038/srep30006
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
[Journal Article] The Neuroprotective Effects of Ratanasampil on Oxidative Stress-Mediated Neuronal Damage in Human Neuronal SH-SY5Y Cells2015
- Author(s)
  Aiqin Zhu, Zhou Wu, Jie Meng, Patrick L. McGeer, Yi Zhu, Hiroshi Nakanishi, and Shizheng Wu
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2015 Pages: 1-10
- DOI
  10.1155/2015/792342
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] Downward spiral of periodontitis and diabetes into Alzheimer's disease: Extending healthy life expectancy through oral health. J2015
- Author(s)
  Hiroshi Nakanishi, Zhou Wu
- Journal Title
  
  J Oral Biosci
  
  Volume: 57 Pages: 139-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05015
[Journal Article] The downwardspiralofperiodontitisanddiabetesinAlzheimer's disease: Extendinghealthylifeexpectancythroughoralhealth2015
- Author(s)
  Hiroshi Nakanishi, Zhou WU
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 57 Issue: 3 Pages: 139-142
- DOI
  10.1016/j.job.2015.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15684
[Journal Article] Cathepsin D deficiency induces oxidative damage in brain pericytes and impairs the blood-brain barrier2015
- Author(s)
  Yoshinori Hayashi Y, Yuka Koga, Xinwen Zhang, Christoph Peters, Yanagawa Y, Zhou Wu, Takeshi Yokoyama, Hiroshi Nakanishi
- Journal Title
  
  Molecular and Cellular Neuroscience
  
  Volume: 64 Pages: 51-60
- DOI
  10.1016/j.mcn.2014.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-26861555, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] The Critical Role of Proteolytic Relay through Cathepsins B and E in the Phenotypic Change of Microglia/Macrophage2015
- Author(s)
  XJunjun Ni, Zhou Wu, Christoph Peterts, Kenji Yamamoto, Hong Qing, and Hiroshi Nakanishi2015
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 35 Issue: 36 Pages: 12488-12501
- DOI
  10.1523/jneurosci.1599-15.2015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] Lessons from Microglia Aging for the Link between Inflammatory Bone Disorders and Alzheimer’s Disease2015
- Author(s)
  Zhou Wu, Hiroshi Nakanishi
- Journal Title
  
  Journal of Immunology Research
  
  Volume: 2015 Pages: 471342-471342
- DOI
  10.1155/2015/471342
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state2014
- Author(s)
  Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
- Journal Title
  
  J Neurosci
  
  Volume: 34 Pages: 3013-3022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659827
[Journal Article] Autophagy in superficial spinal dorsal horn accelerates the cathepsin B-dependent morphine antinociceptive tolerance.2014
- Author(s)
  Hayashi Y, Koga Y, Zhang X, Peters C, Yanagawa Y, Wu Z, Yokoyama T, Nakanishi H.
- Journal Title
  
  Neuroscience
  
  Volume: 275 Pages: 384-94
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592802
[Journal Article] Connection Between Periodontitis and Alzheimer’s Disease: Possible Roles of Microglia and Leptomeningeal Cells2014
- Author(s)
  Zhou Wu, Hiroshi Nakanishi
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 126 Issue: 1 Pages: 8-13
- DOI
  10.1254/jphs.14R11CP
- NAID
  130004684880
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390416
[Journal Article] Connection between periodontitis and Alzheimer's disease: possible roles of microglia and leptomeningeal cells.2014
- Author(s)
  Wu Z, Nakanishi H.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 126 Pages: 8-13
- NAID
  130004684880
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592802
[Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state.2014
- Author(s)
  Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
- Journal Title
  
  J Neurosci
  
  Volume: 34 Pages: 3013-3022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592802
[Journal Article] Novel roles of microglia2014
- Author(s)
  Hiroshi Nakanishi
- Journal Title
  
  Clinical & Experomental Neuroimmunology
  
  Volume: 5 Issue: s1 Pages: 35-40
- DOI
  10.1111/cen3.12161
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390416
[Journal Article] Autophagy in superficial spinal dorsal horn accelerates the cathepsin B-dependent morphine antinociceptive tolerance2014
- Author(s)
  Yoshinori Hayashi Y, Yuka Koga, Xinwen Zhang, Christoph Peters, Yanagawa Y, Zhou Wu, Takeshi Yokoyama, Hiroshi Nakanishi
- Journal Title
  
  Neuroscience
  
  Volume: 275 Pages: 384-394
- DOI
  10.1016/j.neuroscience.2014.06.037
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24791979
[Journal Article] Periphera1 ro1e of cathepsin S in Thl ce11-dependent transition of nerve injury-induced acute pain to a chronic pain state2014
- Author(s)
  Xinwen Zhang,Zhou Wu,Yoshinori ayashi,Ryo Okada R,iroshi Nakanishi
- Journal Title
  
  J Neurosci
  
  Volume: Vo1 34,No. 8 Pages: 3013-3022
- Data Source
  KAKENHI-PROJECT-24659827
[Journal Article] Differential pathways for interleukin-1b production activated by chromogranin A and amyloid β in microglia2013
- Author(s)
  Zhou Wu, Li Sun, Sadayuki Hashioka, Yu S, Schwab C, Ryo Okada, Yoshinori Hayashi, Patrick L McGeer PL, Hiroshi Nakanishi
- Journal Title
  
  Neurobiol Aging
  
  Volume: 34 Issue: 12 Pages: 2715-2725
- DOI
  10.1016/j.neurobiolaging.2013.05.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827, KAKENHI-PROJECT-24791979
[Journal Article] Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia2013
- Author(s)
  Fumiko Takayama, Zhou Wu, Hong Ma HM, Okada R, Yoshinori Hayashi, Hiroshi Nakanishi
- Journal Title
  
  J Neuroimmunol
  
  Volume: 262 Issue: 1-2 Pages: 121-124
- DOI
  10.1016/j.jneuroim.2013.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827, KAKENHI-PROJECT-24791979
[Journal Article] Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-kB activation in microglia2013
- Author(s)
  Zhou Wu, Aiqin Zhu, Fumiko Takayama, Ryo Okada, Yicong Liu, Yuka Harada, Shizheng Wu, Hiroshi Nakanishi
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2013:906726 Pages: 1-10
- DOI
  10.1155/2013/906726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Journal Article] Leptomeningeal cells transduce peripheral macrophages inflammatory signal to microglia in response to Porphyromonas gingivalis LPS2013
- Author(s)
  Yicong Liu, Zhou Wu, Xinwen Zhang, Junjun Ni, Weixian Yu, Yanmin Zhou, Hiroshi Nakanishi
- Journal Title
  
  Mediators Inflamm
  
  Volume: 2013:407562 Pages: 1-11
- DOI
  10.1155/2013/407562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state2013
- Author(s)
  Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
- Journal Title
  
  J Neurosci
  
  Volume: 34 Pages: 3013-3022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416
[Journal Article] Age-dependent neuroinflammatory responses and deficits in long-term potentiation in the hippocampus during systemic inflammation2012
- Author(s)
  Liu X, Wu Z, Hayashi Y, Nakanishi H
- Journal Title
  
  Neuroscience
  
  Volume: 216 Pages: 133-142
- DOI
  10.1016/j.neuroscience.2012.04.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Journal Article] Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-induced Chronic Pain.2012
- Author(s)
  S. Li, Z. Wu, Y. Hayashi, C. Peters, K. Inoue, M. Tsuda, and H. Nakanishi.
- Journal Title
  
  J.Neurosci.
  
  Volume: 32(33) Issue: 33 Pages: 11330-42
- DOI
  10.1523/jneurosci.0677-12.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Journal Article] Phosphatidylserine-containing liposomes : potential pharmacological interventions against inflammatory and immune diseases through the production of prostaglandin E_2 after uptake by myeloid derived phagocytes2011
- Author(s)
  Wu Z, Nakanishi H
- Journal Title
  
  Ach.Immunol.Therap.Exp. 59
  
  Pages: 196-201
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Phosphatidylserine -containing liposomes : potential pharmacological interventions against inflammatory and immune diseases through the production of prostaglandin E_2 after uptake by myeloid derived phagocytes2011
- Author(s)
  Wu Z, Nakanishi H
- Journal Title
  
  Ach.Immunol.Therap.Exp. 59
  
  Pages: 196-201
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2010
- Author(s)
  Terada K, Yamada J, Hayashi Y, Wu Z, Uchiyama Y, Peters C, Nakanishi H.
- Journal Title
  
  Glia. 58(1)
  
  Pages: 114-124
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Phosphatidylserine-containing liposomes inhibit the differentiation of osteoclasts and trabecular bone loss.2010
- Author(s)
  Wu Z, Ma HM, Kukita T, Nakanishi Y, Nakanishi H.
- Journal Title
  
  J Immunol. 15;184(6)
  
  Pages: 3191-3201
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Phosphatidylserine-containing liposomes inhibit the differentiation of osteoclasts and trabecular bone loss.2010
- Author(s)
  Wu Z, Ma HM, Kukita T, Nakanishi Y, Nakanishi H.
- Journal Title
  
  J Immunol. 15;184(6)
  
  Pages: 3191-3201
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Acute p38-mediated inhibition of NMDA-induced outward currents in hippocampal CA1 neurons by interleukin-1β.2010
- Author(s)
  Zhang R, Sun L, Hayashi Y, Liu X, Koyama S, Wu Z, Nakanishi H.
- Journal Title
  
  Neurobiol Dis. 38(1)
  
  Pages: 68-77
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2010
- Author(s)
  Terada K, Yamada J, Hayashi Y, Wu Z, Uchiyama Y, Peters C, Nakanishi H.
- Journal Title
  
  Glia. 58(1)
  
  Pages: 114-124
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Acute p38-mediated inhibition of NMDA-induced outward currents in hippocampal CA1 neurons by interleukin-1β.2010
- Author(s)
  Zhang R, Sun L, Hayashi Y, Liu X, Koyama S, Wu Z, Nakanishi H.
- Journal Title
  
  Neurobiol Dis. 38(1)
  
  Pages: 68-77
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse.2010
- Author(s)
  Sun L, Wu Z, Baba M, Peters C, Uchiyama Y, Nakanishi H.
- Journal Title
  
  Biochem Biophys Res Commun. 399(3)
  
  Pages: 391-395
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse.2010
- Author(s)
  Sun L, Wu Z, Baba M, Peters C, Uchiyama Y, Nakanishi H.
- Journal Title
  
  Biochem Biophys Res Commun. 399(3)
  
  Pages: 391-395
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Microglia-aging : Roles of microglial lysosomal- and mithochndria-derived reactive oxygen species in brain aging2009
- Author(s)
  Nakanishi H, Wu Z
- Journal Title
  
  Behavioral Brain Research 201
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Microglia-aging : Roles of microglial lysosomal- and mithochndria-derived reactive oxygen species in brain aging2009
- Author(s)
  Nakanishi H , Wu Z
- Journal Title
  
  Behavioral Brain Research 201
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons.2008
- Author(s)
  Zhang R, Yamada J, Hayashi Y, Wu Z, Koyama S, Nakanishi H.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 372
  
  Pages: 816-820
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Reduced synaptic acticity precedes synaptic stripping in vagal motoneurons after axotomy2008
- Author(s)
  Yamada J., Hayashi Y., Jinno S., Wu Z., Inoue K., Kohsaka S., Nakanishi H.
- Journal Title
  
  Glia 56
  
  Pages: 1448-1462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Reverse of brain aging by an overexpression of human mitochondrial transcription factor A in mice.2008
- Author(s)
  Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Ochi-Shindou M, Kanki T, Kang D, Sunagawa K, Tsutsui H, Nakanishi H.
- Journal Title
  
  J.Neurosci. 28
  
  Pages: 8624-8634
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Reverse of brain aging by an overexpression of human mitochondrial transcription factor A in mice.2008
- Author(s)
  Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Ochi-Shindou M, Kanki T, Kang D, Sunagawa K, Tsutsui H, Nakanishi H.
- Journal Title
  
  J.Neurosci. 28
  
  Pages: 8624-8634
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Reduced synaptic acticity precedes synaptic stripping in vagal motoneurons after axotomy.2008
- Author(s)
  Yamada J, Hayashi Y, Jinno S, Wu Z, Inoue K, Kohsaka S, Nakanishi H.
- Journal Title
  
  Glia 56
  
  Pages: 1148-1462
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Age-dependent responses of glial cells and leptomeninges during systemic inflammation2008
- Author(s)
  Wu Z., Tokuda Y., Zhang X. W., and Nakanishi H.
- Journal Title
  
  Neurobiol. Disease 32
  
  Pages: 543-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Possible involvement of cathepsin B released by microglia in methylmercury-induced cerebellar pathological changes in the adult rats.2008
- Author(s)
  Sakamoto M, Miyamoto KI, Wu Z, Nakanishi H.
- Journal Title
  
  Neurosci.Lett. 442
  
  Pages: 292-296
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons. Biochem.2008
- Author(s)
  Zhang R, Yamada J, Hayashi Y, Wu Z, Koyama S, Nakanishi H.
- Journal Title
  
  Biophys.Res.Commun. 372
  
  Pages: 816-820
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Possible involvement of cathepsin B released by microglia in methylmercury -induced cerebellar pathological changes in the adult rats.2008
- Author(s)
  Sakamoto M, Miyamoto KI, Wu Z, Nakanishi H.
- Journal Title
  
  Neurosci.Lett. 442
  
  Pages: 292-296
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Possible involvement of cathepsin B released by microglia in methylmercury-induced cerebellar pathological changes in the adult rats2008
- Author(s)
  Sakamoto M., Miyamoto K. I., Wu Z., and Nakanishi H
- Journal Title
  
  Neurosci. Lett 442
  
  Pages: 292-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons2008
- Author(s)
  Zhang R., Yamada J., Hayashi Y., Wu Z., Koyama S., Nakanishi H
- Journal Title
  
  Biochem. Biophys. Res. Commun 372
  
  Pages: 816-820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Reduced synaptic acticity precedes synaptic stripping in vagal motoneurons after axotomy.2008
- Author(s)
  Yamada J, Hayashi Y, Jinno S, Wu Z, Inoue K, Kohsaka S, Nakanishi H.
- Journal Title
  
  Glia 56
  
  Pages: 1148-1462
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Age-dependent responses of glial cells and leptomeninges during systemic inflammation.2008
- Author(s)
  Wu Z, Tokuda Y, Zhang XW, Nakanishi H.
- Journal Title
  
  Neurobiol.Disease 32
  
  Pages: 543-551
- Data Source
  KAKENHI-PROJECT-20592174
[Journal Article] Reverse of brain aging by an overexpression of human mitochondrial transcription factor A in mice2008
- Author(s)
  Hayashi Y., Yoshida M., Yamato M., Ide T., Wu Z., Ochi-Shindou M., Kanki T. Kang D., Sunagawa K., Tsutsui H., and Nakanishi H.
- Journal Title
  
  J. Neurosci 28
  
  Pages: 8624-8634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Age-dependent responses of glial cells and leptomeninges during systemic inflammation.2008
- Author(s)
  Wu Z, Tokuda Y, Zhang XW, Nakanishi H.
- Journal Title
  
  Neurobiol.Disease 32
  
  Pages: 543-551
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid β and interferon-γ-induced microglial activation2007
- Author(s)
  Hashioka, S., Han, Y-H., Fujii, S., Kato, H., Monji, A., Utsumi, H., Sawada, M., Nakanishi H., Kanba, S
- Journal Title
  
  Free Rad. Biol. Med 42
  
  Pages: 945-954
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia.2007
- Author(s)
  Hashioka, S., Han, Y-H., Fujii, S., Kato, H., Monji, A., Utsumi, H., Sawada, M., Nakanishi, H., Kanba, S
- Journal Title
  
  Neurochem. Int. 50
  
  Pages: 499-506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Journal Article] Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid 13 and interferon-y-induced microglial activation.2007
- Author(s)
  Hashioka, S., Han, Y-H., Fujii, S., Kato, H., Monji, A., Utsumi, H., Sawada, M., Nakanishi, H., Kanba, S
- Journal Title
  
  Free Rad. Biol. Med. 42
  
  Pages: 945-954
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Journal Article] Involvement of PGE2 released from leptomeningeal cells in increased expression of TGF-β1 in glial cells and cortical neurons during systemic inflammation2007
- Author(s)
  Wu Z., Hayashi Y. Zhang J., and Nakanishi H.
- Journal Title
  
  J. Neurosci. Res 85
  
  Pages: 184-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice2007
- Author(s)
  Yamasaki R., Zhang J., Koshiishi I., Sastradipura Suniarti D.F.,Wu Z., Peters C., Schwake M., UchiyamaY., Kira J. I., Saftig P., Utsumi H., and Nakanishi H.
- Journal Title
  
  Mol. Cell. Neurosci 35
  
  Pages: 573-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Involvement of PGE2 released from leptomeningeal cells in increased expression of TGF-β1 in glial cells and cortical neurons during systemic inflammation2007
- Author(s)
  Wu, Z., Hayashi, Y., Zhang, J., Nakanishi, H
- Journal Title
  
  J. Neurosci. Res 85
  
  Pages: 184-192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia2007
- Author(s)
  Hashioka S., Han Y. H., Fujii S., Kato H., Monji A., Utsumi H., Sawada M., Nakanishi H., and Kanba S.
- Journal Title
  
  Neurochem. Int 50
  
  Pages: 499-506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Impairment of the microglial responses to the facial nerve axotomy in cathepsin S-deficient mice2007
- Author(s)
  Hao H. P., Doh-ura K, and Nakanishi H.
- Journal Title
  
  J. Neurosci. Res 85
  
  Pages: 2196-2206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Impairment of the microglial responses to the facial berve axotomy in cathepsin S-deficient mice.2007
- Author(s)
  Hao, H.P., Doh-ura, K, Nakanishi, H
- Journal Title
  
  J. Neurosci. Res. 85
  
  Pages: 2196-2206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Journal Article] Involvement of lysosomal storage- induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice2007
- Author(s)
  Yamasaki, R., Zhang, J., Koshiishi, I., Sastradipura, D., Suniarti, F., Wu, Z., Peters, C., Schwake, M., Uchiyama, Y., Kira, J.-I., Saftig, P., Utsumi, H., Nakanishi, H
- Journal Title
  
  Mol. Cell. Neurosci 35
  
  Pages: 573-584
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Impairment of the microglial responses to the facial berve axotomy in cathepsin S-deficient mice2007
- Author(s)
  Hao, H.P., Doh-ura, K., Nakanishi, H
- Journal Title
  
  J. Neurosci. Res 85
  
  Pages: 2196-2206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice.2007
- Author(s)
  Yamasaki, R., Zhang, J., Koshiishi, I., Sastradipura Suniarti, D.F., Wu, Z., Peters, C., Schwake, M., Uchiyama, Y., Kira, J.-I., Saftig, P., Utsumi, H., Nakanishi, H
- Journal Title
  
  Mol. Cell. Neurosci. 35
  
  Pages: 573-584
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Journal Article] Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia2007
- Author(s)
  Hashioka, S., Han, Y-H., Fujii, S., Kato, H., Monji, A., Utsumi, H., Sawada, M., Nakanishi. H., Kanba, S
- Journal Title
  
  Neurochem. Int 50
  
  Pages: 499-506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Phosphatidylserine and phosphatidylcholine- containing liposomes inhibit amyloid β and interferon-γ-induced microglial activation2007
- Author(s)
  Hashioka S., Han Y. H., Fujii S., Kato H., Monji A., Utsumi H., Sawada M., Nakanishi H., and Kanba S.
- Journal Title
  
  Free Rad. Biol. Med 42
  
  Pages: 945-954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592171
[Journal Article] Involvement of PGE_2 released from leptomeningeal cells in increased expression of TGF-β1 in glial cells and cortical neurons during systemic inflammation.2007
- Author(s)
  Wu, Z., Hayashi, Y., Zhang, J., Nakanishi, H
- Journal Title
  
  J. Neurosci. Res. 85
  
  Pages: 184-192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Journal Article] Cell cycle-dependent regulation of kainate-induced inward currents in microglia2006
- Author(s)
  Yamada, J., Sawada, M., Nakanishi, H
- Journal Title
  
  Biochem. Biophys. Res. Commun 349
  
  Pages: 913-919
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Involvement of COX-1 and up-regulated prostaglandin E synthases in phosphatidylserine liposome-induced prostaglandin E2 production of microglia.2006
- Author(s)
  Zhang, J., Fujii, S., Hashioka, S., Tanaka, Y., Wu, Z., Shiratsuchi, A., Nakanishi, Y., Nakanishi, H
- Journal Title
  
  J. Neuroimmunol. 172
  
  Pages: 112-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Journal Article] The intra-arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats.2006
- Author(s)
  Hayashi, Y., Tomimatsu, Y., Suzuki, H., Yamada, J., Yao, H., Kagamiishi, Y., Tateishi, N., Sawada, M., Nakanishi, H
- Journal Title
  
  Neuroscience 142
  
  Pages: 87-96
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Journal Article] Cell cycle-dependent regulation of kainate-induced inward currents in microglia.2006
- Author(s)
  Yamada, J., Sawada, M., Nakanishi, H
- Journal Title
  
  Biochem. Biophys. Res. Commun. 349
  
  Pages: 913-919
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Journal Article] The intra-arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats2006
- Author(s)
  Hayashi, Y., Tomimatsu, Y., Suzuki, H., Yamada, J., Yao, H., Kagamiishi, Y., Tateishi, N., Sawada, M., Nakanishi, H
- Journal Title
  
  Neuroscience 142
  
  Pages: 87-96
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Involvement of COX-1 and up-regulated prostaglandin E synthases in phosphatidylserine liposome-induced prostaglandin E_2 production of microglia2006
- Author(s)
  Zhang, J., Fujii, S., Hashioka, S., Tanaka, Y., Wu, Z., Shiratsuchi, A., Nakanishi, Y., Nakanishi, H
- Journal Title
  
  J. Neuroimmunol 172
  
  Pages: 112-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Leptomeningeal cells activate microglial and astrocytes to induce IL-10 production by releasing pro-inflammatory cytokines during systemic inflammation2005
- Author(s)
  Wu, Z., Zhang, J., Nakanishi, H
- Journal Title
  
  J. Neuroimmunol 167
  
  Pages: 90-98
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Amyloid-β fibril formation is not necessarily required for microglial activation by the peptides2005
- Author(s)
  Hashioka, S., Monji, A., Ueda, T., Kanba, S., Nakanishi, H
- Journal Title
  
  Neurochem. Int 47
  
  Pages: 369-376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Proteolytic degradation of glutamate decarboxylase mediates disinhibition of hippocampal CA3 pyramidal cells in cathepsin D-deficient mice2005
- Author(s)
  Shimizu, T., Hayashi, Y., Yamasaki, R., Yamada, J., Zhang, J., Ukai, K., Koike, M., Mine, K., von Figura, K., Peters, C., Saftig, P., Fukuda, T., Uchiyama, Y., Nakanishi, H
- Journal Title
  
  J. Neurochem 94
  
  Pages: 680-690
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Proteases and synaptic activity.In:Proteases2005
- Author(s)
  Nakanishi H.(分担)
- Journal Title
  
  Biology and Disease.Vol.3, (Eds:Lendeckel, U.and Hooper, N.), Kluwer Academic/Plenum Publishers
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Journal Article] Microglia-aging : Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging. Behav.
- Author(s)
  Nakanishi H, Wu Z.
- Journal Title
  
  Brain Res.
- Data Source
  KAKENHI-PROJECT-20390472
[Journal Article] Microglia-aging : Roles of microglial lysosome- and mitochondria -derived reactive oxygen species in brain aging.
- Author(s)
  Nakanishi H, Wu Z.
- Journal Title
  
  Behav.Brain Res.
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ヒト beta-ディフェンシン-３の歯周病菌LPSにより誘発されるミクログリアの酸化ストレスならびに炎症反応に対する抑制作用2022
- Author(s)
  崎紫陽、井上瑛里加、野中さおり、中西博
- Organizer
  第61回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-21K06383
[Presentation] 歯周病菌LPSによりミクログリアにおいて産生・分泌されるサイトカイン類の網羅的解析2022
- Author(s)
  大森朱莉、大本凜、野中さおり、中西博
- Organizer
  第61回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-21K06383
[Presentation] ヒト beta-ディフェンシン-３の歯周病菌LPSにより誘発されるミクログリアの酸化ストレス・炎症反応に対する抑制メカニズム2022
- Author(s)
  井上瑛里加、湊崎紫陽、野中さおり、中西博
- Organizer
  第61回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-21K06383
[Presentation] アルツハイマー病治療のパラダイムシフト -歯周病とミクログリアの不都合な関係-2020
- Author(s)
  中西　博
- Organizer
  第142回日本薬学会中国四国支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] Involvement of endosomal signaling in gingipain-induced migration, inflammation response and phagocytosis in microglia after activation of PAR2、2019
- Author(s)
  Nonaka S, Iseki A, Amano A, Nakanishi Y, Ni J, Wu Z, Nakanishi H.
- Organizer
  XIV European meeting on glial cells in health and disease (GLIA 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] Secreted gingipains from Porphyromonas gingivalis induce microglia migration through endosomal signaling by protease-activated receptor 22019
- Author(s)
  Nonaka S, Nakanishi H.
- Organizer
  第24回グリア研究会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] Cathepsin H deficiency suppresses hypoxic-ischemia-induced hippocampal atrophy in mice through reduced secretion of IFN-beta from microglia2019
- Author(s)
  Ni J, Wu Z, Nakanishi H,
- Organizer
  第24回グリア研究会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain2019
- Author(s)
  Junjun Ni、中西博、武洲
- Organizer
  第72回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] カテプシン群と痛みの治療2019
- Author(s)
  中西　博
- Organizer
  第18回痛みの研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] 脊髄ミクログリアBKチャネルの神経障害性疼痛における役割2019
- Author(s)
  佐藤泰司、諸橋徹、林良憲、板倉沙也子、川口慎憲、中西博、メレディスアンドレア、石塚俊晶
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] ミクログリアにおけるカテプシン増大と細胞内の分布変化は、酸化ストレスならびに炎症反応を介して認知障害をもたらす2018
- Author(s)
  Junjuin Ni、武洲、林良憲、中西博
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] チベット薬Ratanasampilは低酸素によるミクログリアにおける酸化ストレスならびにNF-kappaB活性化に依存した炎症反応を抑制する2018
- Author(s)
  Jie Meng、Junjun Ni、林　良憲、中西　博、朱　愛琴、武　洲
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] ITPA欠損によるヒトてんかん性脳症のモデルとしての神経幹細胞特異的Itpaノックアウトマウス2018
- Author(s)
  土本大介、古賀祐一郎、林良憲、アボルハッサニノナ、米嶋康臣、中西　博、中別府雄
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] チベット薬Ratanasampilは、低酸素によるミクログリアにおける酸化ストレスならびにNF-kappaB活性化に依存した炎症反応を抑制する2018
- Author(s)
  孟ジェイ、朱愛琴、Junjuin Ni、林良憲、中西博、武洲
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] ブラジル産グリーンプロポリスは、チベット高原に住む高齢者の全身炎症を軽減して認知機能の低下を防ぐ2018
- Author(s)
  Zhu A, Ni J, Meng J, Nakanishi H ,Wu Z
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Involvement of reduced microglial BMAL1 expression in excessive neuroinflammation of APP knock-in (APP-KI) mice.2018
- Author(s)
  Ni J, Wu Z, Nonaka S, Saido TC, Nakanishi H
- Organizer
  第23回グリア研究
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] ミクログリアにおけるカテプシンBの発現増加及び細胞内分布変化はマウスにおける酸化ストレスや炎症反応による認知障害を誘発する2018
- Author(s)
  Junjun Ni、武　洲、林　良憲、中西　博
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] チベット薬Ratanasampilは、低酸素によるミクログリアにおける酸化ストレスならびにNF-κB活性化に依存した炎症反応を抑制する2018
- Author(s)
  Jie Meng, Junjun Ni, Yoshinori Hayashi, Hiroshi Nakanishi, Aiqin Zhu　and Zhou Wu
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Porphyromonas gingivalis 菌慢性末梢感染により老齢femaleマウスミクログリアにおける抗炎症能が低下する2018
- Author(s)
  中西　悠梨香
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] ブラジル産グリーンプロポリスはチベット高原に住む高齢者の全身炎症を軽減して認知機能の低下を防ぐ2018
- Author(s)
  朱　愛琴、Junjun Ni、Jie Meng、中西　博、武　洲
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K19650
[Presentation] 歯周病菌によるアルツハイマー様脳病態の発症と原因酵素としてのカテプシン群の役割2017
- Author(s)
  武　洲、中西　博
- Organizer
  第59回歯科基礎医学会学術大会学術シンポジウム
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] 歯周病と認知症:増悪機構の解明と今後の展望2017
- Author(s)
  武洲、中西博
- Organizer
  第90本薬理学会年会年会企画シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] 歯周病と認知機能：増悪機序の解明と今後の展望2017
- Author(s)
  武　洲、中西　博
- Organizer
  第90回日本薬理学会年会（年会企画シンポジウム：口腔ブレインサイエンスに学ぶ健康長寿）
- Place of Presentation
  長崎新聞文化ホール（長崎）
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Rheum tanguticum in activated microglia.2017
- Author(s)
  Meng J, Ni J, Wu Z, Zhu A, Nakanishi H
- Organizer
  第90回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] 口内を清潔に保って認知症を防げ2017
- Author(s)
  中西　博
- Organizer
  新学術領域「グリアアセンブリ」公開シンポジウム
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Porphyromonas gingivalis promotes cell migration and an inflammatory response of microglia through the gingipain-mediated activation of protease-activated receptor-2.2017
- Author(s)
  Liu Y, Wu Z, Nakanishi H
- Organizer
  第22回グリア研究会
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Increased expression and altered subcellular distribution of cathepsin B in microglia induces cognitive impairment through oxidative stress and inflammatory response during aging.2017
- Author(s)
  Ni J, Wu Z, Nakanishi H
- Organizer
  第22回グリア研究会
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Gingipain Induce Microglia Migration through activation of protease-activated receptor-2. 95th Annuak Meeting of International Association for Dental Research2017
- Author(s)
  Yicong Liu , Zhou Wu and Hiroshi Nakanishi
- Organizer
  IADR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 8The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-22017
- Author(s)
  Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Hiroshi Nakanishi
- Organizer
  95tth Annual Meeting of International Association for Dental Research (IADR2017)
- Place of Presentation
  サンフランシスコ（USA）
- Year and Date
  2017-03-24
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease- activated receptor-2 (PAR-2).2017
- Author(s)
  Liu Y, Wu Z, Kadowaki T, Nakanishi H
- Organizer
  第90本薬理学会年会
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2).2017
- Author(s)
  Liu Y, Wu Z, Kadowaki T, Nakanishi H
- Organizer
  第90本薬理学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] 歯周病菌によるアルツハイマー様脳病態の発症と原因酵素としてのカテプシン群の役割2017
- Author(s)
  武洲、中西博
- Organizer
  第59回歯科基礎医学会学術大会学術シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] 皮膚ケラチノサイトのカテプシンEを介した神経障害性疼痛の慢性化メカニズムの解明2017
- Author(s)
  張　競、林　良憲、中西　博
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)、2017
- Author(s)
  Yicong Liu, Zhou Wu, Hiroshi Nakanishi,
- Organizer
  95tth Annual Meeting of International Association for Dental Research (IADR2017)
- Place of Presentation
  サンフランシスコ（USA）
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Hiroshi Nakanishi
- Organizer
  95tth Annual Meeting of International Association for Dental Research (IADR2017)
- Place of Presentation
  サンフランシスコ（USA）
- Year and Date
  2017-03-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Gingipains induce microglial migration through activation protease-activated receptor-2 (PAR-2).2017
- Author(s)
  Liu Y, Wu Z, Nakanishi H
- Organizer
  95th Annual Meeting of International Association for Dental Research (IADR2017)
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] 口内を清潔に保って認知症を防げ2017
- Author(s)
  中西博
- Organizer
  新学術領域「グリアアセンブリ」公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] L-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia2017
- Author(s)
  Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia2017
- Author(s)
  Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] 歯周病と認知機能：増悪機序の解明と今後の展望2017
- Author(s)
  武　洲、中西　博
- Organizer
  第90回日本薬理学会年会（年会企画シンポジウム：口腔ブレインサイエンスに学ぶ健康長寿）
- Place of Presentation
  長崎新聞文化ホール（長崎）
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Increased expression and altered subcellular distribution of Cathepsin B in microglia induces cognitive impairment through oxidative stress and inflammatory response during aging2017
- Author(s)
  Junjun Ni, Zhou Wu and Hiroshi Nakanishi
- Organizer
  The 22nd Annual Meeting of Japan Glia
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] 歯周病と認知機能：増悪機序の解明と今後の展望2017
- Author(s)
  武　洲、中西　博
- Organizer
  第90回日本薬理学会年会（年会企画シンポジウム：口腔ブレインサイエンスに学ぶ健康長寿）
- Place of Presentation
  長崎新聞文化ホール（長崎）
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia、2017
- Author(s)
  Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 歯周病と認知機能：増悪機序の解明と今後の展望2017
- Author(s)
  武　洲、中西　博
- Organizer
  第90回日本薬理学会年会（年会企画シンポジウム：口腔ブレインサイエンスに学ぶ健康長寿）
- Place of Presentation
  長崎新聞文化ホール（長崎）
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Rheum tanguticum in activated microglia.2017
- Author(s)
  Meng J, Ni J, Wu Z, Zhu A, Nakanishi H
- Organizer
  第90回日本薬理学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] 皮膚ケラチノサイトのカテプシンEを介した神経障害性疼痛の慢性化メカニズムの解明2017
- Author(s)
  張競、林良憲、中西博
- Organizer
  第59回歯科基礎医学会学術大会学術シンポジウム
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Hiroshi Nakanishi
- Organizer
  95tth Annual Meeting of International Association for Dental Research (IADR2017)
- Place of Presentation
  サンフランシスコ（USA）
- Year and Date
  2017-03-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] 歯周病と認知症：増悪機構の解明と今後の展望2017
- Author(s)
  武　洲、中西　博
- Organizer
  第90本薬理学会年会年会企画シンポジウム
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Critical roles of cathepsin B in Alzheimer’s disease-like phenotypes following chronic systemic exposure to Porphyromonas gingivalis2017
- Author(s)
  Zhou Wu Junjun Ni, Yicong Liu and Hiroshi Nakanishi
- Organizer
  ISN-ESN Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia2017
- Author(s)
  Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Porphyromonas gingivalis promotes cell migration and an inflammatory response of microglia through the gingipain-mediated activation of protease-activated receptor-2.2017
- Author(s)
  Liu Y, Wu Z, Nakanishi H
- Organizer
  第22回グリア研究会
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Gingipains induce microglial migration through activation protease-activated receptor-2 (PAR-2).2017
- Author(s)
  Liu Y, Wu Z, Nakanishi H
- Organizer
  95th Annual Meeting of International Association for Dental Research (IADR2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-22017
- Author(s)
  Yicong Liu, Zhou Wu and Hiroshi Nakanishi
- Organizer
  The 22nd Annual Meeting of Japan Glia
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Increased expression and altered subcellular distribution of cathepsin B in microglia induces cognitive impairment through oxidative stress and inflammatory response during aging.2017
- Author(s)
  Ni J, Wu Z, Nakanishi H
- Organizer
  第22回グリア研究会
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2（PAR-2）の活性化を介したミクログリアの細胞遊走誘導2016
- Author(s)
  劉　訳聡、武　洲、門脇知子、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016
- Author(s)
  武　洲、中西　博
- Organizer
  第58回歯科基礎医学会学術大会（サテライトシンポジウム：健康長寿社会を目指す口腔ブレインサイエンスの最前線）
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Pathological roles of microglial cathepsins in chronic pain2016
- Author(s)
  Hiroshi Nakanishi
- Organizer
  XVth Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  ポートローズ、スロベニア
- Year and Date
  2016-09-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016
- Author(s)
  孟ジェイ、武　洲、門脇知子、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2（PAR-2）の活性化を介したミクログリアの細胞遊走誘導2016
- Author(s)
  劉　訳聡、武　洲、朱　愛琴、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses,2016
- Author(s)
  Junjun Ni, Zhou Wu, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2（PAR-2）の活性化を介したミクログリアの細胞遊走誘導2016
- Author(s)
  劉　訳聡、武　洲、朱　愛琴、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses2016
- Author(s)
  Junjun Ni, Zhou Wu, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Pathological roles of microglial cathepsins in chronic pain2016
- Author(s)
  Hiroshi Nakanishi
- Organizer
  XVth Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  ポートローズ、スロベニア
- Year and Date
  2016-09-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses,2016
- Author(s)
  Junjun Ni, Zhou Wu, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016
- Author(s)
  武　洲、中西　博
- Organizer
  第58回歯科基礎医学会学術大会（サテライトシンポジウム：健康長寿社会を目指す口腔ブレインサイエンスの最前線）
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016
- Author(s)
  Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016
- Author(s)
  Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016
- Author(s)
  孟ジェイ、武　洲、朱　愛琴、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016
- Author(s)
  Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi,
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016
- Author(s)
  Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016
- Author(s)
  武　洲、中西　博
- Organizer
  第58回歯科基礎医学会学術大会（サテライトシンポジウム：健康長寿社会を目指す口腔ブレインサイエンスの最前線）
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-16H05848
[Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016
- Author(s)
  孟ジェイ、武　洲、門脇知子、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016
- Author(s)
  孟ジェイ、武　洲、門脇知子、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Pathological roles of microglial cathepsins in chronic pain2016
- Author(s)
  Hiroshi Nakanishi
- Organizer
  XVth Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  ポートローズ、スロベニア
- Year and Date
  2016-09-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016
- Author(s)
  武　洲、中西　博
- Organizer
  第58回歯科基礎医学会学術大会（サテライトシンポジウム：健康長寿社会を目指す口腔ブレインサイエンスの最前線）
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2（PAR-2）の活性化を介したミクログリアの細胞遊走誘導2016
- Author(s)
  劉　訳聡、武　洲、朱　愛琴、中西　博
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses2016
- Author(s)
  Junjun Ni, Zhou Wu, Hiroshi Nakanishi
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PUBLICLY-16H01340
[Presentation] Modulator actions of microglial cathepsins in brain diseases2015
- Author(s)
  Hiroshi Nakanishi
- Organizer
  Cold Spring Harbor Asia（CSHA Conference 2015）: New Insights into Glia Function & Dysfunction
- Place of Presentation
  Worldhotel Grand Dushulake Suzhou
- Year and Date
  2015-06-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Periodontitis and Alzheimer’s disease (AD) (1): A possible role of leptomeninges in transduction of inflammatory signals from peripheral macrophages to microglia in the response to lipopolyssacharide from Porphyromonas gingivalis2015
- Author(s)
  Yicong Liu、Zhou Wu、 Hiroshi Nakanishi
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Modulator actions of microglial cathepsins in brain diseases2015
- Author(s)
  Hiroshi Nakanishi
- Organizer
  Cold Spring Harbor Asia（CSHA Conference 2015）
- Place of Presentation
  Worldhotel Grand Dushulake Suzhou（中国、蘇州市）
- Year and Date
  2015-06-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] ATPならびにPorphyromonas gingivalis（PG）局所注入により惹起されるミクログリア突起の集積とその日内変化に関する生体イメージング解析2015
- Author(s)
  髙山扶美子、林良憲、武洲、中西博
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ新潟（新潟）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] ATPならびにPorphyromonas gingivalis（PG）局所注入により惹起されるミクログリア突起の集積とその日内変化に関する生体イメージング解析2015
- Author(s)
  髙山扶美子、林良憲、武洲、中西
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Lessons from cathepsin deficient mice on human brain diseases2015
- Author(s)
  Hiroshi Nakanishi
- Organizer
  The 4th International Conference and Exhibition on Neurology & Therapeutics
- Place of Presentation
  Holiday Inn Rome Aurelia（ローマ）
- Year and Date
  2015-07-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Critical roles of cathepsin B in AD-like phenotypes in middle-aged mice following chronic systemic treatment with lipopolyssacharide from Porphyromonas gingivalis2015
- Author(s)
  Junjun Ni、Zhou Wu、 Hiroshi Nakanishi
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ新潟（新潟）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] Lessons from cathepsin deficient mice on human brain diseases2015
- Author(s)
  Hiroshi Nakanishi
- Organizer
  The 4th International Conference and Exhibition on Neurology & Therapeutics
- Place of Presentation
  Holiday Inn Rome Aurelia
- Year and Date
  2015-07-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Periodontitis and Alzheimer’s disease (AD) (2): Critical roles of cathepsin B in AD-like phenotypes in middle-aged mice following chronic systemic treatment with lipopolyssacharide from Porphyromonas gingivalis2015
- Author(s)
  Junjun Ni、Zhou Wu、 Hiroshi Nakanishi
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K15684
[Presentation] Involvement of brain pericyte damage in neuropathological changes associated eith lysosomal storage2015
- Author(s)
  Zhou Wu, Ryo Okada、Hiroshi Nakanishi
- Organizer
  The 4th International Conference and Exhibition on Neurology & Therapeutics
- Place of Presentation
  Holiday Inn Rome Aurelia（ローマ）
- Year and Date
  2015-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05015
[Presentation] カテプシンSは告げんの日無い変化がもたらすミクログリアならびにニューロン機能の日内変化2014
- Author(s)
  高山扶美子、林　良憲、武　洲、中西　博
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学ラマツィーニホール（福岡）
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] プロポリスのカテプシンS 発現制御を介したTh1 応答抑制作用2014
- Author(s)
  張馨文、武洲、中西博
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] クログリアの2種類の突起の日内変化に関する形態学的ならびに生体イメージング解析2014
- Author(s)
  髙山扶美子、林良憲、武洲、中西博
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Cathepsin B is a possible phenotype switch along the M1-M2 phenotypic continuum of microglia/macrophages2014
- Author(s)
  倪　軍軍、武　洲、中西　博
- Organizer
  第19回グリア研究会
- Place of Presentation
  東京商工会議所（東京）
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Involvement of cathepsin S in the diurnal morphological and functional changes of cortical microglial processes2014
- Author(s)
  高山扶美子、林良憲、武洲、中西博
- Organizer
  第21回日本時間生物学会学術大会
- Place of Presentation
  九州大学医学部百年講堂（福岡）
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014
- Author(s)
  林　良憲、中西　博
- Organizer
  研究会　「痛みと痛覚情動連関の神経機構」
- Place of Presentation
  生理学研究所（岡崎）
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Cathepsin B is positive phenotype switch the M1-M2 phenotypic continuum of microglia/macrophages2014
- Author(s)
  JunJun Ni、武　洲、中西　博
- Organizer
  第19回グリア研究会
- Place of Presentation
  東京
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] 神経障害性疹痛の慢性化におけるカテプシンSの役割2014
- Author(s)
  張馨文、武洲、林良憲、中西博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2014-03-19
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014
- Author(s)
  林　良憲、中西　博
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学ラマツィーニホール（福岡）
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014
- Author(s)
  林　良憲、中西　博
- Organizer
  第19回グリア研究会
- Place of Presentation
  東京商工会議所（東京）
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] カテプシンH欠損による実験的自己免疫性脳脊髄炎の発症促進とT細胞サブセットの変動2014
- Author(s)
  岡田　亮、中西　博
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Microg1ia1 circadian c1ock contro1s microg1ia-synapse interactions in the hea1thy brain,in Symposium of"Why do microg1ia exist in the brain : As a target for treatment of neuro1ogica1 disorders"2013
- Author(s)
  中西博
- Organizer
  シンポジウム,第90回日本生理学会大会
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] クロモグラニンA(CGA)によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明2013
- Author(s)
  武洲、中西博
- Organizer
  第55回歯科基礎医学学術大会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2013-09-22
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] Microg1ia1 circadian c1ock contro1s diurna1 changes in synaptic strength through microg1ia-synaptic interactions2013
- Author(s)
  中西博
- Organizer
  シンポジウム、Neuro20l3
- Place of Presentation
  国立京都国際会館
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] Potential roles of chromogranin A in cathepsin B-dependent IL-1βproduction by microglia in Alzheimer’s disease2013
- Author(s)
  Wu Z, Nakanishi H
- Organizer
  第86回日本薬理学会年会,
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] Microglial circadian clock controls microglia-synapse interactions in the healthy brain2013
- Author(s)
  林　良憲, 中西　博
- Organizer
  第86回日本薬理学会年会、シンポジウム：Roles of microglia and astrocytes in synaptic reotganization: New trends in glial research
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] Regulation of microglia-synapse interactions and synaptic strength by microglial circadian clock2013
- Author(s)
  林良憲, 中西博
- Organizer
  第86回日本薬理学会年会、シンポジウム : Roles of microglia and astrocytes in synaptic reotganization : New trends in glial research
- Place of Presentation
  福岡(招待講演)
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Microglial circadian clock controls microglia-synapse interactions in the healthy brain2013
- Author(s)
  中西　博
- Organizer
  第90回日本生理学会大会、シンポジウム：Why do microglia exist in the brain: As a terget for treatment of neurological disorders
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] Microglial circadian clock controls microglia-synapse interactions in the healthy brain2013
- Author(s)
  中西博
- Organizer
  第90回日本生理学会大会, シンポジウム : Why do microglia exist in the brain: As a terget for treatment of neurological disorders
- Place of Presentation
  東京(招待講演)
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Batten病モデルマウスにおける脳ベリサイトの消失と血液脳関門の破綻2013
- Author(s)
  岡田亮、武洲、見軍軍、中西博
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡大学
- Year and Date
  2013-11-16
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] Regu1ation of microg1ia-synapse interactions and synaptic strength by microg1ia1 circadian c1ock,in Symposium of"Ro1es of microg1ia and astrocytes in synaptic reorganization : New trends in g1ia1 research"2013
- Author(s)
  林良憲,中西博
- Organizer
  シンポジウム,第86回日本薬理学会年会
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] Cathepsin B-dependent novel IL-1β production pathway in microglia2013
- Author(s)
  Wu Z, Nakanishi H,
- Organizer
  Kudai Oral Bioscience 2013
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] ミクログリアの電気生理学的解析2012
- Author(s)
  中西博
- Organizer
  包括型脳科学研究推進支援ネットワーク・夏のワークショップ, 「グリア機能解析」チュートリアル
- Place of Presentation
  仙台(招待講演)
- Year and Date
  2012-07-27
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] クロモグラニンAの慢性炎症性疼痛における役割の解析2012
- Author(s)
  孫麗, 武　洲, 林　良憲, 中西　博
- Organizer
  第54回歯科基礎医学会学術大会
- Place of Presentation
  郡山
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] ミクログリアの産生するカテプシン群の慢性疼痛における役割2012
- Author(s)
  中西博
- Organizer
  平成24年度生理研研究会「痛み研究の新たな展開」
- Place of Presentation
  岡崎(招待講演)
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアの産生するカテプシン群の慢性疼痛における役割2012
- Author(s)
  中西　博
- Organizer
  平成24年度生理研研究会「痛み研究の新たな展開」
- Place of Presentation
  岡崎
- Invited
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] ミクログリアの電気生理学的解析2012
- Author(s)
  中西博
- Organizer
  包括型脳科学研究推進支援ネットワーク・夏のワークショップ,「グリア機能解析jチユートリアル
- Place of Presentation
  仙台
- Year and Date
  2012-07-27
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] ミクログリアの産生するカテプシン群の慢性疹痛における役割2012
- Author(s)
  中西博
- Organizer
  平成年度生理研研究会「痛み研究の新たな展開」
- Place of Presentation
  岡崎(教育講演)
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] クロモグラニンAはβアミロイドよりも強力にミクログリアにおけるIL-1β産生を誘導する2012
- Author(s)
  武　洲, 中西　博
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] NMDAレセプターとミクログリア, CINP・NP2012合同年会, シンポジウム:　NMDAレセプター神経疾患の分子病態を探る2012
- Author(s)
  中西　博
- Organizer
  CINP・NP2012合同年会
- Place of Presentation
  宇都宮
- Invited
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] NMDAレセプターとミクログリア2012
- Author(s)
  中西博,林良憲
- Organizer
  CINP・NP20l2合同年会,シンポジウム: NMDAレセプター神経疾患の分子病態を探る
- Place of Presentation
  宇都宮
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] NMDAレセプターとミクログリア2012
- Author(s)
  中西博
- Organizer
  CINP・NP2012合同年会, シンポジウム : NMDAレセプター神経疾患の分子病態を探る
- Place of Presentation
  宇都宮(招待講演)
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Microglial circadian clock controls microglia-synapse interactions through P2Y12 receptors and cathepsin S expression2012
- Author(s)
  中西　博
- Organizer
  The 15th Annual Meeting of the Korean Society for Brain and Neural Science in Symposium of Glial Neuroscience
- Place of Presentation
  ソウル
- Invited
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] 神経障害性疼痛におけるミクログリアのカテプシンSの関与2010
- Author(s)
  張馨文、孫麗、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ミクログリアの産生するカテプシンS の神経障害性疼痛発症における役割2010
- Author(s)
  張馨文、林良憲、武洲、中西博
- Organizer
  第15回グリア研究会
- Place of Presentation
  福岡
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] S-ketamine preferentially inhibits neuropathic pain through the neuronal-based and microglia-related mechanisms.2010
- Author(s)
  Kawaji K, Hayashi Y, Nakanishi H
- Organizer
  Neuroscience 2010
- Place of Presentation
  サンジエゴ
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Microglial cathepsin B : a strategic target for neuroprotective agents.2010
- Author(s)
  Wu Z, Nakanishi H
- Organizer
  BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010
- Place of Presentation
  Shanghai
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 慢性末梢炎症によるミクログリア活性化と海馬LTPの障害2010
- Author(s)
  劉霞、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 慢性末梢炎症によるミクログリア活性化と海馬LTP障害2010
- Author(s)
  劉霞、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] A possible involvement of cathepsin B in nociceptive processing through the processing and secretion of interleukin-1 family from microglia.2010
- Author(s)
  Sun L, Wu Z, Hayashi Y, Nakanishi H
- Organizer
  Neuroscience 2010
- Place of Presentation
  サンジエゴ
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010
- Author(s)
  武洲, 劉霞, 中西博
- Organizer
  The 1^<st> International Congress on Controversies in Longevity, Health and Aging.
- Place of Presentation
  バルセロナ
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] S-ketamine preferentially inhibits neuropathic pain through the neuronal-based and microglia-related mechanisms.2010
- Author(s)
  河路広大, 林良憲, 中西博
- Organizer
  Neuroscience 2010
- Place of Presentation
  サンジエゴ
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] カテプシンB阻害による疼痛制御2010
- Author(s)
  中西博
- Organizer
  第5回九大痛みの研究会
- Place of Presentation
  福岡
- Year and Date
  2010-02-19
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 神経障害性疼痛におけるミクログリアのカテプシンSの関与2010
- Author(s)
  張馨文、孫麗、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 炎症性疼痛発症におけるミクログリアのカテプシンBの関与2010
- Author(s)
  孫麗、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ホスファチジルセリンリポソームによる炎症性骨破壊抑制メカニズムの解析2010
- Author(s)
  武洲、馬紅梅、久木田敏夫、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Preferential inhibitory effects of S-ketamine on neuropatic pain through both the neuronal based and microglia related mechanisms.2010
- Author(s)
  Hayashi Y, Kawaji K, Nakanishi H
- Organizer
  The 29^<th> Naito Conference : Glia World.
- Place of Presentation
  湘南村
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Acute p38-mediated inhibition of K_Ca channels activated by Ca^<2+> influx through both NMDA receptor and voltage-gated Ca^<2+> channels by interleukin-1β2010
- Author(s)
  Hayashi Y, Zhang R, Sun L, Wu Z, Nakanishi H
- Organizer
  Neuroscience 2010
- Place of Presentation
  サンジエゴ
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] S-ケタミンのNMDA電流ならびにミクログリア活性化の優位阻害による神経障害性疼痛に対する抑制作用2010
- Author(s)
  林良憲、河路広大、中西博
- Organizer
  第63回日本薬理学会西南部会
- Place of Presentation
  鹿児島
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ホスファチジルセリンリポソームによる骨形成の促進2010
- Author(s)
  馬紅梅、武洲、李銀姫、久木田敏夫、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010
- Author(s)
  武洲, 劉霞, 中西博
- Organizer
  The 1^<st> International Congress on Controversies in Longevity, Health and Aging.
- Place of Presentation
  バルセロナ
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 中年ルイスラットにおけるアジュバント関節炎に伴うミクログリア活性化と海馬長期増強の障害2010
- Author(s)
  武洲、劉霞、中西博
- Organizer
  第63回日本薬理学会西南部会
- Place of Presentation
  鹿児島
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] S-ケタミンのNMDA電流ならびにミクログリア活性化の優位阻害による神経障害性疼痛に対する抑制作用2010
- Author(s)
  林良憲、河路広大、中西博
- Organizer
  第63 回日本薬理学会西南部会
- Place of Presentation
  鹿児島
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] カテプシンB阻害による疼痛制御2010
- Author(s)
  中西博
- Organizer
  第5回九大痛みの研究会
- Place of Presentation
  福岡
- Year and Date
  2010-02-19
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Preferential inhibitory effects of S-ketamine on both NMDA receptor currents and neuropathic pain.2010
- Author(s)
  Kawaji K, Hayshi Y, Koyano K, Yokoyama T, Nakanishi H
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010
- Author(s)
  Wu, Liu X, Nakanishi H
- Organizer
  The 1st International Congress on Controversies in Longevity, Health and Aging
- Place of Presentation
  Barcelona
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ホスファチジルセリンリポソームによる炎症性骨破壊抑制メカニズムの解析2010
- Author(s)
  武洲、馬紅梅、久木田敏夫、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミクログリアのリソソーム・ミトコンドリア系を標的としたグリア創薬に可能性2010
- Author(s)
  中西博
- Organizer
  第130回日本薬学会年会、130回年会祈念融合型シンポジウム「グリア創薬の最前線と可能性」
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Protective effects of microglia-conditioned medium against NMDA-induced dendritic injury through an inhibition of non-selective cation conductance.2010
- Author(s)
  Hayashi Y, Fujita S, Odagaki Y, Shinagawa R, Kagamiishi Y, Nakanishi H
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Acute p38-mediated inhibition of K_Ca channels activated by Ca^<2+> influx through both NMDA receptor and voltage-gated Ca^<2+> channels by interleukin-1β2010
- Author(s)
  Hayashi Y, Zhang R, Sun L, Wu Z, Nakanishi H.
- Organizer
  Neuroscience 2010
- Place of Presentation
  サンジエゴ
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Neuroprotection of microglia-conditioned medium on excitotoxic neuronal injury through inhibition of large cation conductance.2010
- Author(s)
  Hayashi Y, Fujita S, Odagaki Y, Shinagawa R, Kagamiishi Y, Nakanishi H
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 炎症性疼痛発症におけるミクログリアのカテプシンBの関与2010
- Author(s)
  孫麗、武洲、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ホスファチジルセリンリポソームによる骨形成の促進2010
- Author(s)
  馬紅梅、武洲、李銀姫、久木田敏夫、中西博
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミクログリアの産生するカテプシンBの炎症性疼痛発症における役割2010
- Author(s)
  孫麗、武洲、中西博
- Organizer
  第15回グリア研究会
- Place of Presentation
  福岡
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Preferential inhibitory effects of S-ketamine on both NMDA receptor currents and neuropathic pain.2010
- Author(s)
  Kawaji K, Hayshi Y, Koyano K, Yokoyama T, Nakanishi H
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Protective effects of microglia-conditioned medium against NMDA-induced dendritic injury through an inhibition of non-selective cation conductance.2010
- Author(s)
  Hayashi Y, Fujita S, Odagaki Y, Shinagawa R, Kagamiishi Y, Nakanishi H
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミクログリアのリソソーム・ミトコンドリア系を標的としたグリア創薬に可能性2010
- Author(s)
  中西博
- Organizer
  第130回日本薬学会年会、130回年会祈念融合型シンポジウム「グリア創薬の最前線と可能性」
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010
- Author(s)
  Wu, Liu X, Nakanishi H
- Organizer
  The 1st International Congress on Controversies in Longevity, Health and Aging
- Place of Presentation
  Barcelona
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 中年ルイスラットにおけるアジュバント関節炎に伴うミクログリア活性化と海馬長期増強の障害2010
- Author(s)
  武洲、劉霞、中西博
- Organizer
  第63回日本薬理学会西南部会
- Place of Presentation
  鹿児島
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Differebtial inolvement of astrocytes and microglia in neuronal survival after hypoglossal nerve injury.2010
- Author(s)
  Yamada J, Jinno S, Nakanishi H
- Organizer
  The 29^<th> Naito Conference : Glia World.
- Place of Presentation
  湘南村
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ミクログリアの産生するカテプシンBの炎症性疼痛発症における役割2010
- Author(s)
  孫麗、武洲、中西博
- Organizer
  第15回グリア研究会
- Place of Presentation
  福岡
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Neuroprotection of microglia-conditioned medium on excitotoxic neuronal injury through inhibition of large cation conductance.2010
- Author(s)
  Hayashi Y, Fujita S, Odagaki Y, Shinagawa R, Kagamiishi Y, Nakanishi H
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Microglial cathepsin B :A strategic target for neuroprotective agents.2010
- Author(s)
  武洲, 中西博
- Organizer
  BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010.
- Place of Presentation
  上海
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Preferential inhibitory effects of S-ketamine on neuropatic pain through both the neuronal based and microglia related mechanisms.2010
- Author(s)
  林良憲, 河路広大, 中西博
- Organizer
  The 29^<th> Naito Conference : Glia World.
- Place of Presentation
  湘南村
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Differebtial inolvement of astrocytes and microglia in neuronal survival after hypoglossal nerve injury.2010
- Author(s)
  Yamada J, Jinno S, Nakanishi H
- Organizer
  The 29^<th> Naito Conference : Glia World.
- Place of Presentation
  湘南村
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミクログリアの産生するカテプシンS の神経障害性疼痛発症における役割2010
- Author(s)
  張馨文、林良憲、武洲、中西博
- Organizer
  第15回グリア研究会
- Place of Presentation
  福岡
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Microglial cathepsin B : A strategic target for neuroprotective agents.2010
- Author(s)
  武洲, 中西博
- Organizer
  BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010.
- Place of Presentation
  上海
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] A possible involvement of cathepsin B in nociceptive processing through the processing and secretion of interleukin-1 family from microglia.2010
- Author(s)
  孫麗, 武洲, 林良憲, 中西博
- Organizer
  Neuroscience 2010
- Place of Presentation
  サンジエゴ
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Microglial cathepsin B : a strategic target for neuroprotective agents.2010
- Author(s)
  Wu Z, Nakanishi H
- Organizer
  BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010
- Place of Presentation
  Shanghai
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Microglia-aging : Roles of microglial lysosome-and mitochondria-derived reactive oxygen species in brain aging.2009
- Author(s)
  中西博
- Organizer
  第52回日本神経化学会、シンポジウム「ミクログリアの機能と病態-最近の研究動向と将来の展望-」
- Place of Presentation
  群馬県伊香保
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 末梢炎症によるミクログリア活性化と脳老化の促進2009
- Author(s)
  武洲、劉霞、中西博
- Organizer
  第14回グリア研究会
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Age-dependent differential microglial and astrocytic responses through leptomeninges during systemic inflammation.2009
- Author(s)
  武洲, 徳田幸恵, 張馨文, 中西博
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Microglia-aging : Roles of microglial lysosome-and mitochondria-derived reactive oxygen species in brain aging.2009
- Author(s)
  中西博
- Organizer
  第52回日本神経化学会、シンポジウム「ミクログリアの機能と病態-最近の研究動向と将来の展望-」
- Place of Presentation
  群馬県伊香保
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Extracellular nucleotide-mediated reduced synaptic activityprecedes microglial synaptic stripping after an axotomy.2009
- Author(s)
  中西博, 山田純
- Organizer
  International Symposium on Purinergic Signalling in New Strategy of Drig Discovery, Fukuoka Purine 2009
- Place of Presentation
  福岡
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 末梢炎症により惹起される脳炎症の老化による増悪-鍵を握る免疫担当細胞ミクログリアの動態について-2009
- Author(s)
  中西博
- Organizer
  第52回秋期日本歯周病学術大会シンポジウム
- Place of Presentation
  宮崎
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Extracellular nucleotide-mediated reduced synaptic activity precedes microglial synaptic stripping after axotomy2009
- Author(s)
  Nakanishi H.
- Organizer
  Fukuoka Purine
- Place of Presentation
  福岡
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] インターロイキン-1βのp38MAPキナーゼの活性化を介したNMDAにより惹起されるCa^<2+>活性化K^+電流の抑制作用2009
- Author(s)
  Zhang R,劉霞、孫麗、林良憲、武洲、中西博
- Organizer
  第62回日本薬理学会西南部会
- Place of Presentation
  愛媛
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2009
- Author(s)
  Nakanishi H, Terada K, Yamada J, Hayashi Y, Wu Z
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 末梢炎症により惹起される脳炎症の老化による増悪:鍵を握る脳の免疫担当細胞ミクリグリアの動態について2009
- Author(s)
  中西博
- Organizer
  第52回秋期日本歯周病学術大会、シンポジウム「歯周組織の免疫応答から考える全身への影響」
- Place of Presentation
  宮崎
- Year and Date
  2009-10-11
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 運動神経軸索切断後のアストロサイト形態・ミクログリアの形態の比較検討2009
- Author(s)
  山田純、神野尚三、中西博
- Organizer
  第14回グリア研究会
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ミクログリアのニューロン保護作用:NMDA誘発こうフィン毒性に対するミクログリア培養上清の保護メカニズムの解析2009
- Author(s)
  林良憲、中西博
- Organizer
  第62回日本薬理学会西南部会
- Place of Presentation
  愛媛
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 末梢炎症により惹起される脳炎症の老化による増悪:鍵を握る脳の免疫担当細胞ミクリグリアの動態について2009
- Author(s)
  中西博
- Organizer
  第52回秋期日本歯周病学術大会、シンポジウム「歯周組織の免疫応答から考える全身への影響」
- Place of Presentation
  宮崎
- Year and Date
  2009-10-11
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミクログリアのニューロン保護作用:NMDA誘発こうフィン毒性に対するミクログリア培養上清の保護メカニズムの解析2009
- Author(s)
  林良憲、中西博
- Organizer
  第62回日本薬理学会西南部会
- Place of Presentation
  愛媛
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Microglia-aging : Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging2009
- Author(s)
  中西博
- Organizer
  第52回日本神経化学大会シンポジウム
- Place of Presentation
  群馬県伊香保
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Age-dependent differential phenotypic changes of glial cells by systemic inflammation.2009
- Author(s)
  武洲, 中西博
- Organizer
  9^<th> European Meeting on Glial Cells in Health and Disease.
- Place of Presentation
  パリ
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Age-dependent differential microglial and astrocytic responses through leptomeninges during systemic inflammation.2009
- Author(s)
  Wu Z, Tokuda Y, Zhang XW, Nakanishi H
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Age-dependent differential phenotypic changes of glial cells by systemic inflammation.2009
- Author(s)
  武洲, 中西博
- Organizer
  9^<th> European Meeting on Glial Cells in Health and Disease.
- Place of Presentation
  パリ
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Extracellular nucleotide-mediated reduced synaptic activity precedes microglial synaptic stripping after an axotomy. International Symposium on Purinergic Signalling in New Strategy of Drig Discovery2009
- Author(s)
  中西博, 山田純
- Organizer
  Fukuoka Purine 2009
- Place of Presentation
  福岡
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Microglia-aging : Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging2009
- Author(s)
  Nakanishi H.
- Organizer
  第52回日本神経化学大会シンポジウム
- Place of Presentation
  群馬県伊香保
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Extracellular nucleotide-mediated reduced synaptic activity precedes microglial synaptic stripping after axotomy2009
- Author(s)
  中西博
- Organizer
  Fukuoka Purine
- Place of Presentation
  福岡
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 末梢炎症により惹起される脳炎症の老化による増悪-鍵を握る免疫担当細胞ミクログリアの動態について-2009
- Author(s)
  中西博
- Organizer
  第52回秋期日本歯周病学術大会シンポジウム
- Place of Presentation
  宮崎
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 運動神経軸索切断後のアストロサイト形態・ミクログリアの形態の比較検討2009
- Author(s)
  山田純、神野尚三、中西博
- Organizer
  第14回グリア研究会
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microgli2009
- Author(s)
  Nakanishi H., et al
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2009
- Author(s)
  Nakanishi H, Terada K, Yamada J, Hayashi Y, Wu Z
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] インターロイキン-1βのp38MAPキナーゼの活性化を介したNMDAにより惹起されるCa^<2+>活性化K^+電流の抑制作用2009
- Author(s)
  Zhang R, 劉霞、孫麗、林良憲、武洲、中西博
- Organizer
  第62回日本薬理学会西南部会
- Place of Presentation
  愛媛
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia2009
- Author(s)
  Nakanishi H., et al.
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] 末梢炎症によるミクログリア活性化と脳老化の促進2009
- Author(s)
  武洲、劉霞、中西博
- Organizer
  第14回グリア研究会
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia2008
- Author(s)
  Nakanishi H., et al.
- Organizer
  米国神経科学会議
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミトコンドリア転写因子Aの過剰発現によるミトコンドリア内レドックス制御ならびに老化に伴う脳機能低下の制御2008
- Author(s)
  中西博、林良憲、井手友美、武洲
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Phospathidylserine-containing liposomes ameliorates the cytokine imbalance in the ankle joints of adjuvant arthritic rats.2008
- Author(s)
  馬紅梅、武洲、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 末梢炎症に対する髄膜-グリア連関の反応の老化に伴う変容2008
- Author(s)
  武洲, 中西博
- Organizer
  第61回日本西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Age-dependent differentiatial regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008
- Author(s)
  武洲, 中西博
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] ミトコンドリア転写因子Aの過剰発現によるミクログリア内レドックス制御ならびに老化に伴う脳機能低下の抑制2008
- Author(s)
  中西博, 他
- Organizer
  第61回日本西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2008
- Author(s)
  Nakanishi H, Terada K, Yamada J, Hayashi Y, Wu Z
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia2008
- Author(s)
  Nakanishi H., et al.
- Organizer
  米国神経科学会議
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 中高年における慢性末梢炎症は深刻な脳炎症を引き起こす2008
- Author(s)
  徳田幸恵、張馨文、武洲、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Phospathidylserine-containing liposomes ameliorates the cytokine imbalance in the ankle joints of adjuvant arthritic rats.2008
- Author(s)
  馬紅梅、武洲、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons.2008
- Author(s)
  張馨文, 武洲, 中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Involvement of extracellular nucleotides in microglial synaptic strippingresponse.2008
- Author(s)
  中西博
- Organizer
  第81回日本薬理学会年会、シンポジウム「細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与」
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] TFAM過剰発現によるミクログリア内レドックス制御と老化に伴う脳機能低下の防止2008
- Author(s)
  林良憲、井手友美、中西博
- Organizer
  第13回グリア研究会
- Place of Presentation
  東京
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2008
- Author(s)
  中西博
- Organizer
  第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御一分子ダイナミクスと疾病への関与
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Age-dependent differential regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008
- Author(s)
  Wu Z., Nakanishi H.
- Organizer
  米国神経科学会議
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Age-dependent differentiation of the barrier function of the leptomeninges in the cerebral cortex by activated glial cells during the systemic inflammation.2008
- Author(s)
  武洲, 徳田幸恵, 張馨文, 中西博
- Organizer
  第26回CINP
- Place of Presentation
  ミュンヘン
- Year and Date
  2008-07-13
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Reduced synaptic activity mediated by extracellular nucleotides precedes synaptic stripping after an axotomy.2008
- Author(s)
  Yamada J, Jinno S, Nakanishi H
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Synaptic Stripping における細胞外ヌクレオチドの関与2008
- Author(s)
  中西博
- Organizer
  第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Overexpression of human TFAM prevents age-dependent memory impairement in mice by suppression of mitochondrial oxidative stress.2008
- Author(s)
  Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Nakanishi H
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2008
- Author(s)
  中西博
- Organizer
  第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Reduced synaptic activity mediated by extracellular nucleotides precedes synaptic stripping after an axotomy.2008
- Author(s)
  Yamada J, Jinno S, Nakanishi H
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Novel therapeutuc intervention with overexpression of TFAM against the age-dependent memory impairement.2008
- Author(s)
  Hayshi Y, Yoshida M, Yamamto M, Ide T, Kang D, Nakanishi H
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] TFAM過剰発現によるミクログリア内レドックス制御と老化に伴う脳機能低下の防止2008
- Author(s)
  林良憲、井手友美、中西博
- Organizer
  第13回グリア研究会
- Place of Presentation
  東京
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Age-dependent differentiatial regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008
- Author(s)
  武洲, 中西博
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Involvement of cathepsin Bin the processing and secretion of interleukin-1β inchromogranin A-stimulated microglia2008
- Author(s)
  Nakanishi H., et al
- Organizer
  米国神経科学会議
- Place of Presentation
  ワシントン DC
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Age-dependent differentiation of the barrier function of the leptomeninges in the cerebral cortex by activated glial cells during the systemic inflammation.2008
- Author(s)
  Wu Z, Tokuda Y, Zhang XW, Nakanishi H
- Organizer
  第26回CINP
- Place of Presentation
  ミュンヘン
- Year and Date
  2008-07-13
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2008
- Author(s)
  中西博
- Organizer
  第81回日本薬理学会総会、シンポジウム=細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Synaptic Stripping における細胞外ヌクレオチドの関与2008
- Author(s)
  中西博
- Organizer
  第81回日本薬理学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] 破骨前駆細胞の貪食機能に着目した新たな骨破壊抑制法2008
- Author(s)
  武洲、馬紅梅、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Involvement of extracellular nucleotides in microglial synaptic stripping response.2008
- Author(s)
  中西博
- Organizer
  第81回日本薬理学会年会、シンポジウム「細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与」
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 破骨前駆細胞の貪食機能に着目した新たな骨破壊抑制法2008
- Author(s)
  武洲、馬紅梅、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] ミトコンドリア転写因子Aの過剰発現によるミトコンドリア内レドックス制御ならびに老化に伴う脳機能低下の制御2008
- Author(s)
  中西博、林良憲、井手友美、武洲
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 末梢炎症に対する髄膜-グリア連関の汎脳性の老化に伴う変容2008
- Author(s)
  武洲、中西博
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Involvement of p38 MAPK in interleukin-1b-induced inhibition of NMDA-induced outward currents in hippocampal neurons2008
- Author(s)
  Zhang R., Nakanishi H.
- Organizer
  Berlin Brain Days 2008
- Place of Presentation
  ベルリン
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons.2008
- Author(s)
  Zhang R, Wu Z, Nakanishi H
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] 細胞内標識法を用いたミクログリアならびにアストロサイト突起の微細構造の解析2008
- Author(s)
  山田純、神野尚三、中西博
- Organizer
  第13回グリア研究会
- Place of Presentation
  東京
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia2008
- Author(s)
  Nakanishi H., et al.
- Organizer
  米国神経科学会議
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] 末梢炎症に対する髄膜-グリア連関の汎脳性の老化に伴う変容2008
- Author(s)
  武洲、中西博
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Age-dependent differential regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008
- Author(s)
  Wu Z., Nakanishi H.
- Organizer
  米国神経科学会議
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] 細胞内標識法を用いたミクログリアならびにアストロサイト突起の微細構造の解析2008
- Author(s)
  山田純、神野尚三、中西博
- Organizer
  第13回グリア研究会
- Place of Presentation
  東京
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2008
- Author(s)
  Nakanishi H, Terada K, Yamada J, Hayashi Y, Wu Z
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Overexpression of human TFAM prevents age-dependent memory impairement in mice by suppression of mitochondrial oxidative stress.2008
- Author(s)
  Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Nakanishi H
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] 中高年における慢性末梢炎症は深刻な脳炎症を引き起こす2008
- Author(s)
  徳田幸恵、張馨文、武洲、中西博
- Organizer
  第50基礎歯科医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Age-dependent differential regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008
- Author(s)
  Wu Z., Nakanishi H.
- Organizer
  米国神経科学会議
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20390472
[Presentation] Novel therapeutuc intervention with overexpression of TFAM against the age-dependent memory impairement.2008
- Author(s)
  Hayshi Y, Yoshida M, Yamamto M, Ide T, Kang D, Nakanishi H
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-20592174
[Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2008
- Author(s)
  中西博
- Organizer
  第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-15082204
[Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice2007
- Author(s)
  Nakanishi H., Wu Z., and Ochi-Shindou M
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Systemic inflammation induces age-dependent defferential activation of glial cells through the leptomeninges.2007
- Author(s)
  Wu, Z., Nakanishi, H
- Organizer
  8 th Euroglia Meeting
- Year and Date
  2007-09-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Systemic inflammation induces age-dependent defferential activation ofglial cells through the leptomeninges2007
- Author(s)
  Wu Z. and Nakanishi H.
- Organizer
  第8回ヨーロッパグリア(Eurogha)会議
- Place of Presentation
  ロンドン
- Year and Date
  2007-09-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice2007
- Author(s)
  Nakanishi, H., Wu, H., Ochi-Shindou, M
- Organizer
  37th Society for Neuroscience Meeting
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Systemic inflammation induces age-dependent differential activation of glial cells through the leptomeninges.2007
- Author(s)
  Wu Z. and Nakanishi H.
- Organizer
  第8回ヨーロッパグリア(Euroglia)会議
- Place of Presentation
  ロンドン
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Modulation of NMDA receptor-mediated responses by microglial secretingsoluble factors2007
- Author(s)
  Hayashi Y. and Nakanishi H.
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Induction of age-related differential cytokine responses in the brain through microglia by systemic inflammation2007
- Author(s)
  Wu Z.and Nakanishi H.
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Systemic inflammation induces age-dependent defferential activation of gilal cell sthrough the leptomeninges.2007
- Author(s)
  Wu, Z・Nakanishi, H.
- Organizer
  第8回ヨーロッパグリア(Euroglia) 会議
- Place of Presentation
  ロンドン
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-15082204
[Presentation] Systemic inflammation induces age-dependent defferential activation of glial cells through the leptomeninges.2007
- Author(s)
  Wu Z.and Nakanishi H.
- Organizer
  第8回ヨーロッパグリア(Euroglia)会議
- Place of Presentation
  ロンドン
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2007
- Author(s)
  中西博
- Organizer
  Synaptic Strippingにおける細胞外ヌクレオチドの関与学会等名第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御一分子ダイナミクスと疾病への関与
- Place of Presentation
  横浜
- Year and Date
  2007-03-17
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Systemic inflammation induces age-dependent defferential activation ofglial cells through the leptomeninges2007
- Author(s)
  Wu Z., Nakanishi H.
- Organizer
  第8回ヨーロッパグリア(Euroglia)会議
- Place of Presentation
  ロンドン
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice.2007
- Author(s)
  Nakanishi H., Wu Z., and Ochi-Shindou M.
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Induction of age-related differential cytokine responses in the brain throughmicroglia by systemic inflammation2007
- Author(s)
  Wu Z., Nakanishi H.
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Induction of age-related differential cytokine responses in the brain through microglia by systemic inflammation2007
- Author(s)
  Wu, Z., Nakanishi, H
- Organizer
  37 th Society for Neuroscience Meeting
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Modulation of NMDA receptor-mediated responses by microglial secreting soluble factors.2007
- Author(s)
  Hayashi Y.and Nakanishi H.
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Modulation of NMDA receptor-mediated responses bymicroglial secreting soluble factors.2007
- Author(s)
  Hayashi, Y., Nakanishi, H
- Organizer
  37 th Society for Neuroscience Meeting
- Year and Date
  2007-11-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice2007
- Author(s)
  Nakanishi H., Wu Z., and Ochi-Shindou M
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Systemic inflammation induces age- dependent defferential activation of glial cells through the leptomeninges2007
- Author(s)
  Wu, Z., Nakanishi, H
- Organizer
  18th Euroglia Meeting
- Year and Date
  2007-09-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Systemic inflammation induces age-dependent defferential activation of glial cells through the leptomeninges2007
- Author(s)
  Wu Z.and Nakanishi H.
- Organizer
  第8回ヨーロッパグリア(Euroglia)会議
- Place of Presentation
  ロンドン
- Year and Date
  2007-09-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Modulation of NMDA receptor-mediated responses by microglial secreting soluble factors2007
- Author(s)
  Hayashi Y.and Nakanishi H.
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice2007
- Author(s)
  Nakanishi H., et al
- Organizer
  米国神経科学会議
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19592171
[Presentation] Induction of age-related differential cytokine responses in the brain through microglia by systemic inflammation.2007
- Author(s)
  Wu, Z., Nakanishi, H
- Organizer
  37 th Society for Neuroscience Meeting
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Modulaton of NMDA receptor-mediated responses by microglial secreting soluble factors.2007
- Author(s)
  Hayashi, Y・Nakanishi, H.
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-15082204
[Presentation] Modulation of NMDA receptor-mediated responses bymicroglial secreting soluble factors2007
- Author(s)
  Hayashi, Y., Nakanishi, H
- Organizer
  37 th Society for Neuroscience Meeting
- Year and Date
  2007-11-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Induction of age-related differential cytokine responses in thebrain through microglia by systemic inflammation2007
- Author(s)
  Wu Z. and Nakanishi H.
- Organizer
  第37回北米神経科学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice.2007
- Author(s)
  Nakanishi, H., Wu, Z., Ochi-Shindou, M
- Organizer
  37 th Society for Neuroscience Meeting
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] The intra-arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats.2006
- Author(s)
  Hayashi, Y., Suzuki, H., Sawada, M., Nakanishi, H
- Organizer
  36 th Society for Neuroscience Meeting
- Place of Presentation
  Atlanta
- Year and Date
  2006-10-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] ミクログリアによる神経保護機構:闇と光のスイッチング機構2006
- Author(s)
  中西博
- Organizer
  第18回日本神経免疫学会、シンポジウム「免疫学的機序による神経細胞傷害」
- Place of Presentation
  名古屋
- Year and Date
  2006-03-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613010
[Presentation] The intra- arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats2006
- Author(s)
  Hayashi, Y., Suzuki, H., Sawada, M., Nakanishi, H
- Organizer
  36th Society for Neuroscience Meeting
- Place of Presentation
  Atlanta
- Year and Date
  2006-10-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] ミクログリアによる神経保護機構:闇と光のスイッチング機構2006
- Author(s)
  中西博
- Organizer
  第18回日本神経免疫学会、シンポジウム「免疫学的機序による神経細胞傷害」
- Place of Presentation
  名古屋
- Year and Date
  2006-03-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] Deficiency of lysosomal proteases and disorderdes neuronal and microglial functions2005
- Author(s)
  中西博
- Organizer
  第48回日本神経化学会、理事会企画公開シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2005-09-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] ミクログリアのマクロファージ様機能と脳特異的機能2005
- Author(s)
  中西博
- Organizer
  第17回日本神経免疫学会、モーニングセミナー
- Place of Presentation
  福岡
- Year and Date
  2005-03-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390495
[Presentation] 歯周病菌による脳髄膜を介したミクログリアの活性化
- Author(s)
  武　洲、中西　博
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Batten病モデルマウスにおける脳ペリサイトの酸化ストレス障害と血液脳関門の破綻
- Author(s)
  岡田　亮、武　洲、倪　軍軍、中西　博
- Organizer
  第18回グリア研究会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] クロモグラニンA（CGA）によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明
- Author(s)
  武　洲、中西　博
- Organizer
  第55回歯科基礎医学学術大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割
- Author(s)
  張　馨文、武　洲、林　良憲、中西　博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] クロモグラニンA（CGA）によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明
- Author(s)
  武　洲、中西　博
- Organizer
  第55回歯科基礎医学学術大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] 神経障害性トプ痛の慢性化におけるカテプシンSの役割
- Author(s)
  張　馨文、武　洲、林　良憲、中西　博
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡大学
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] クロモグラニンA（CGA）によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明
- Author(s)
  武　洲、中西　博
- Organizer
  第55回歯科基礎医学学術大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] A big channel in small glia as a promising molecular target for the treatment of opioid-induced hyperalgesia
- Author(s)
  林　良憲、中西　博
- Organizer
  第120回日本解剖学会総会・第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場（神戸）
- Year and Date
  2015-03-21 – 2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアのカテプシンS発現リズムによるシナプス強度の調節機構の解明
- Author(s)
  林　良憲、小柳悟、楠瀬直樹、岡田　亮、武　洲、斉藤秀俊、大戸茂弘、高坂新一、井上和秀、中西　博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] 歯周病菌による脳髄膜を介したミクログリアの活性化
- Author(s)
  武　洲、中西　博
- Organizer
  第56回歯科基礎医学会学術大会サテライトシンポジウム
- Place of Presentation
  福岡国際センター
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割
- Author(s)
  張　馨文、武　洲、林　良憲、中西　博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] Microglial circadian clock controls diurnal changes in synaptic strength through microglia-synaptic interactions
- Author(s)
  中西　博
- Organizer
  Neuro2013
- Place of Presentation
  国立京都国際会館
- Invited
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Batten病モデルマウスにおける脳ペリサイトの酸化ストレス障害と血液脳関門の破綻
- Author(s)
  岡田　亮、武　洲、倪　軍軍、中西　博
- Organizer
  第18回グリア研究会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] 2種類のミクログリア突起の日内変化に関する形態学的ならびに生体イメージング解析
- Author(s)
  高山　扶美子　林　良憲、武　洲、中西　博
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際センター
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] Novel roles of microglia
- Author(s)
  中西　博
- Organizer
  第1回 MS Summer College
- Place of Presentation
  電気ビルみらいホール＆カンファレンス（福岡）
- Year and Date
  2014-08-02 – 2014-08-03
- Invited
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] The possible link between periodontitis and Alzheimer's disease
- Author(s)
  武　洲、中西　博
- Organizer
  中国薬理学会・老年医学会・認知機能障害と関連疾患シンポジウム
- Place of Presentation
  中国　青海省西寧市
- Year and Date
  2014-08-09 – 2014-08-11
- Invited
- Data Source
  KAKENHI-PROJECT-24592802
[Presentation] Batten病モデルマウスにおける脳ペリサイトの消失と血液脳関門の破綻、第66回日本薬理学会西南部会
- Author(s)
  岡田　亮、武　洲、倪　軍軍、中西　博
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡大学
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割
- Author(s)
  張　馨文、武　洲、林　良憲、中西　博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] Microglial circadian clock controls diurnal changes in synaptic strength through microglia-synaptic interactions
- Author(s)
  中西　博
- Organizer
  Neuro2013
- Place of Presentation
  国立京都国際会館
- Invited
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] 歯周病菌によるアルツハイマー様脳病態の促進メカニズム
- Author(s)
  武　洲、中西　博
- Organizer
  第88回日本薬理学学会年会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-03-18 – 2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-24390416

1. YAMAMOTO Kenji (40091326)

# of Collaborated Projects: 19 results

# of Collaborated Products: 0 results
2. TAKE Hiro (10420598)

# of Collaborated Projects: 9 results

# of Collaborated Products: 116 results
3. TSUKUBA Takayuki (30264055)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. AKAMINE Akifumi (00117053)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 坂井英昭 (40225769)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MONJI Akira (00294942)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HAYASHI Yoshinori (80582717)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
8. IWATA Koichi (60160115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SHINODA Masamichi (20362238)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. HORI Nobuaki (60037520)

# of Collaborated Projects: 2 results

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11. 西村英紀 (80208222)

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# of Collaborated Products: 0 results
12. SHINDOU Mayumi (10444796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. KOBAYASHI Masayuki (00300830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. AOKI Yosuke (80049030)

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15. IKAI Atsushi (50011713)

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16. KATO Ihachi (30005087)

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17. KUNIMATSU Kazushi (20170011)

# of Collaborated Projects: 1 results

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18. YOSHIMINE Yoshito (80183705)

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19. MAEDA Hidefumi (10284514)

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20. Yamashita Akiko (70511319)

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21. 筑波知子 (70336080)

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22. 岡元邦彰 (10311846)

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23. 田中嘉孝 (20217095)

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24. 岩下未咲 (80611326)

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25. 倪軍軍 (00783953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
26. 野中さおり (40767787)

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# of Collaborated Products: 6 results
27. 小田康祐 (60571255)

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28. 坂口剛正 (70196070)

# of Collaborated Projects: 1 results

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29. TAKAYAMA Fumiko

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30. 金井貞

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31. 浅尾哲次

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. TETSUJI Asao

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# of Collaborated Products: 0 results
33. 浅尾哲治

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. SATOH Yasushi

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# of Collaborated Products: 1 results
35. 高橋寿明

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# of Collaborated Products: 1 results
36. 羽鳥勇太

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# of Collaborated Products: 1 results
37. 井上和秀

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# of Collaborated Products: 1 results

HIROSHI Nakanishi 中西 博

中西 博 ナカニシ ヒロシ

NAKANISHI Hiroshi 中西 博

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Regulatory mechanisms of the gliosis through TLR3/IFN-b signaling mediated by microgliaPrincipal Investigator

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Possible involvement of impaired intrinsic microglial clock in Periodontotis-associated exacerbation of Alzheimer's diseasePrincipal Investigator

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ミクログリアのナイトライフの解析から捉える概日リズム障害発症メカニズムPrincipal Investigator

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Analysis of Porphyromonas gingivalis-induced neuroinflammation by multi-photon imaging of microglia dynamicsPrincipal Investigator

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Study on a microglial phenotypic switch with a focus on proteolytic responsePrincipal Investigator

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Critical roles of the chromogranin A-cathepsin B system in a transition of acute pain to a chronic pain statePrincipal Investigator

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Involvement of endosomal Toll-like receptors in the development of neuropathic painPrincipal Investigator

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Inhibition of bone destruction by phosphatidylserine-containing liposomes based on t he regulation of phagocytes functionsPrincipal Investigator

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HIROSHI Nakanishi 中西博

中西博ナカニシヒロシ

NAKANISHI Hiroshi 中西博