• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

OZAWA Shogo  小沢 正吾

ORCIDConnect your ORCID iD *help
… Alternative Names

小沢 正吾  オザワ ショウゴ

小澤 正吾  オザワ ショウゴ

Less
Researcher Number 20185581
External Links
Affiliation (based on the past Project Information) *help 2007 – 2009: 岩手医科大学, 薬学部, 教授
2006: 国立医薬品食品衛生研究所, 薬理部, 室長
1999 – 2001: 国立医薬品食品衛生研究所, 薬理部, 室長
1994: 慶応義塾大学, 医学部, 助手
1993 – 1994: 慶應義塾大学, 医学部, 助手
1990: 慶應義塾大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Environmental pharmacy / 応用薬理学・医療系薬学
Except Principal Investigator
応用薬理学・医療系薬学 / Human pathology / Laboratory medicine
Keywords
Principal Investigator
phytoestrogens / estrogen responsiveness / gene expression / detoxification / Sulfotransferase / Drug Metabolizing enzymes / Human / Estrogenicity / 代謝活性化 / 植物エストロゲン … More / エストロゲン応答性 / 遺伝子発現 / 解毒的代謝 / 硫酸転移酵素 / 薬物代謝酵素 / ヒト / 内分泌撹乱作用 / cDNAの発現系 / 癌原性N-ヒドロキシアリールアミン / cDNAクローニング / フェノール硫酸転移酵素 … More
Except Principal Investigator
代謝的活性化 / Gene expression / Sulfotransferase / Acetyltransferase / Metabolic activation / Drug metabolizing enzymes / Carcinogenicity / Mutagenicity / Ames test / ベンチジン / サルモネラ菌 / N,O‐アセチル転移反応 / アリルアミン / 異所遺伝子発現 / アセチル化酵素遺伝子 / アセチル化酵素 / Anes試験 / 異種細胞内発現 / 硫酸転移酵素 / アセチル転移酵素 / 代謝活性化 / 薬物代謝酵素 / 発癌性 / 変異原性 / Ames試験 / エピジェネティクス / 薬剤感受性 / ゲノム不安定化 / 癌 / コピー数多型 / ヒトゲノム / 薬剤反応性 / GeneChip / 網羅的解析 / gene dosage effect / 薬物動態関連遺伝子 / 遺伝子多型 / CNV / 遺伝子コピー数多型 / 遺伝的多型 / メフェニトイン / チトクロームP450 / 薬理遺伝学 / 酵素欠損 / 個人差 / 薬物代謝 / 副作用 / 癌原性アリルアミン / 分子クローニング / スルホトランスフェラーゼ / ベンズピレン水酸化 / メフェニトイン水酸化 / 癌原物質 / 遺伝薬理学 / チトクロムPー450 Less
  • Research Projects

    (8 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (10 People)
  •  Estimation of the role of genomic instability on drug response and its application for cancer chemotherapy.

    • Principal Investigator
      HABANO Wataru
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Iwate Medical University
  •  Development of the Analytical Methods for the Evaluation of Copy Number Variations of Drug Metabolizing Enzyme Related Genes in Japanese Population

    • Principal Investigator
      ISHIDA Seiichi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      National Institute of Health Sciences
  •  Biochemical and molecular mechanisms of beneficial effects for human health by phytoestrogensPrincipal Investigator

    • Principal Investigator
      OZAWA Shogo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      National Institute of Health Sciences
  •  癌原物質の活性化を行うヒト肝スルホトランスフェラーゼの構造と遺伝的多型の解析

    • Principal Investigator
      山添 康
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  薬物代謝酵素の欠損及び多型に起因する副作用発現の分子薬理学的解析

    • Principal Investigator
      安盛 俊雄
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Keio University
  •  フェノール硫酸転移酵素の機能及びその遺伝的欠損と疾患との関連Principal Investigator

    • Principal Investigator
      小沢 正吾
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Keio University
  •  Establishment of high sensitive Salmonella tester strains expressing mammalian acetvltransferase and sulfotransferase

    • Principal Investigator
      KATO Ryuichi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Keio University
  •  癌原物質の活性化を行うヒト肝チトクロムPー450の薬理遺伝学差異の研究

    • Principal Investigator
      KATO Ryuichi
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University

All 2011 2010 2009 2007

All Journal Article Presentation Book

  • [Book] How DNA microarray technology contributes to the retinoid evaluations. In "Vitamin A : New Research" (Ed. Lossing IT.)2007

    • Author(s)
      Ishida S, Tanabe H, Shinozaki Y, Koyano S, Kagechika H, Shudo K, Ozawa S, Sawada JI, Ohno Y, Inoue K.
    • Publisher
      Nova Scientific Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-18590545
  • [Journal Article] Altered expression of GADD45 genes during the development of chemical-mediated liver hypertrophy and liver tumor promotion in rats2011

    • Author(s)
      Ozawa S, Gamou T, Habano W, et al
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 36 Issue: 5 Pages: 613-623

    • DOI

      10.2131/jts.36.613

    • NAID

      10029481415

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590402
  • [Journal Article] Super-induced gene expression of the N-methyl-D-aspartate receptor 2C subunit in chemical-induced hypertrophic liver in rats2011

    • Author(s)
      Nemoto K, Tanaka T, Ikeda A, Ito S, Mizukami M, Hikida T, Gamou T, Habano W, Ozawa S, Inoue K, Yoshida M, Nishikawa A, Degawa M.
    • Journal Title

      J Toxicol Sci

      Volume: 36(5) Pages: 507-14

    • NAID

      10029481028

    • Data Source
      KAKENHI-PROJECT-21590402
  • [Journal Article] Induction of CYP1 family members under low-glucose conditions requires AhR expression and occurs through the nuclear translocation of AhR2011

    • Author(s)
      Terashima J, Habano W, Gamou T, Ozawa S.
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 26(6) Pages: 577-83

    • NAID

      130004933497

    • Data Source
      KAKENHI-PROJECT-21590402
  • [Journal Article] Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells2011

    • Author(s)
      Habano W, Gamo T, Terashima J, Sugai T, Otsuka K, Wakabayashi G, Ozawa S.
    • Journal Title

      BMC Cancer

      Volume: 11 Pages: 81-81

    • NAID

      130004640031

    • Data Source
      KAKENHI-PROJECT-21590402
  • [Journal Article] Altered expression of GADD45 genes during the development of chemical-mediated liver hypertrophy and liver tumor promotion in rats2011

    • Author(s)
      Ozawa S, Gamou T, Habano W, Inoue K, Yoshida M, Nishikawa A, Nemoto K, Degawa M.
    • Journal Title

      J Toxicol Sci

      Volume: 36(5) Pages: 613-23

    • NAID

      10029481415

    • Data Source
      KAKENHI-PROJECT-21590402
  • [Journal Article] Induction of CYP1 Family Members under Low-glucose Conditions Requires AhR Expression and Occurs through the Nuclear Translocation of AhR2011

    • Author(s)
      Terashima J, Habano W, Gamou T, Ozawa S
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 26 Issue: 6 Pages: 577-583

    • DOI

      10.2133/dmpk.DMPK-11-RG-054

    • NAID

      130004933497

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590402
  • [Journal Article] CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers2009

    • Author(s)
      Habano W, Gamo T, Sugai T, Otsuka K, Wakabayashi G, Ozawa S.
    • Journal Title

      Int J Oncol

      Volume: 34(4) Pages: 1085-1

    • Data Source
      KAKENHI-PROJECT-21590402
  • [Presentation] Global DNA methylation analysis in Caco-2 and LS180 colon cancer cells2011

    • Author(s)
      Habano W, Gamou T, Terashima J, Ozawa S.
    • Organizer
      日本薬物動態学会第26回年会
    • Place of Presentation
      広島
    • Year and Date
      2011-11-16
    • Data Source
      KAKENHI-PROJECT-21590402
  • [Presentation] Global DNA methylation analysis in Caco-2 and LS180 colon cancer cells2011

    • Author(s)
      Habano W, Gamou T, Terashima J, Ozawa S
    • Organizer
      日本薬物動態学会第26回年回
    • Place of Presentation
      広島国際会議場(広島市)
    • Year and Date
      2011-11-16
    • Data Source
      KAKENHI-PROJECT-21590402
  • [Presentation] Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells2010

    • Author(s)
      Habano W, Gamou T, Terashima J, Sugai T, Ozawa
    • Organizer
      日本薬物動態学会第25回年会
    • Place of Presentation
      さいたま
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-PROJECT-21590402
  • [Presentation] Methylation of PXR, VDR, and PRMT1 genes and their roles in the regulation of CYP3A4 expression in colon cancer cells2009

    • Author(s)
      Habano W, Gamou T, Terashima J, Sugai T, Ozawa
    • Organizer
      日本薬物動態学会第24回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-21590402
  • [Presentation] Analysis of Copy Number Variations (CNVs) of Drug Metabolizing Enzyme Related Genes in Japanese2007

    • Author(s)
      Ishida S, Tanabe H, Sawada JI, Ozawa S, Nakazawa K.
    • Organizer
      8th International ISSX Meeting
    • Place of Presentation
      Sendai
    • Year and Date
      2007-10-09
    • Data Source
      KAKENHI-PROJECT-18590545
  • 1.  YASUMORI Toshio (70182350)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  YAMAZOE Yasushi (00112699)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KATO Ryuichi (40112685)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  NAGATA Kiyoshi (80189133)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  TANABE Hideyuki (50261178)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  ISHIDA Seiichi (10270505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  HABANO Wataru (50332979)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 8.  蒲生 俊恵 (00464701)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  菅井 有 (20187628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 10.  FUJITA Masataka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi