SHINMOTO Michie 新本美智枝

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SHINMOTO Micie 新本美智枝

SHIMMOTO Michie 新本美智枝

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Researcher Number	20216237
External Links
Affiliation (based on the past Project Information) *help	2016 – 2017: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員 2014: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員 2008: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 2000 – 2002: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 1999 – 2000: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 … More 1998: The Tokyo Metropolitan Institute of Medical Science, Clinical Genetics Researche, 臨床遺伝学研究部門, 研究員 1998: The Tokyo Metropolitan Institute of Medical Science, Department of Clinical Gene, 臨床遺伝学研究部門, 研究員 1997: (財)東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1996: 財団法人東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1994 – 1996: 財団法人東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1994: (財)東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1993: 臨床遺伝学研究部門, 研究員 1993: 財団法人東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 Less
Review Section/Research Field	Principal Investigator Human genetics / Genome biology Except Principal Investigator 応用薬理学・医療系薬学 / Functional biochemistry / Molecular biology / Pediatrics
Keywords	Principal Investigator ガラクトシアリドーシス / カルボキシペプチダーゼ / protective protein / gene overlap / phospholipid transfer protein / galactosialidosis / 保護蛋白 / beta-ガラクトシダーゼ / ノイラミニダーゼ / 保護タンパク … More / β-ガラクトシダーゼ / グアニン4重鎖 / Rif1 / HEATドメイン / 染色体高次構造 / 染色体高次構造多量体化 / 天然変性タンパク質ドメイン / DHX36 / FANCJ / G4結合ドメイン / 多量体化 / グアニン４重鎖DMA … More Except Principal Investigator 保護蛋白質 / ガラクトシアリドーシス / リソソーム / α-ガラクトシダーゼ / ファブリー病 / サポシン / 多機能性蛋白 / リソソーム酵素 / アンチセンスオリゴDNA / 複製起点 / 複製タイミング / Cdc7キナーゼ / Fabry disease / 酵素補充療法 / α-Galactosidase / Lysosome / beta-ガラクトシダーゼ / シアリダーゼ / 酸性カルボキシペプチダーゼ / エステラーゼ / デアミダーゼ / エンドセリン / リン脂質転送蛋白質 / 遺伝子重複 / β-ガラクトシダーゼ / 保護蛋白質欠損症 / バイオセンサー / カルボキシペプチダーゼ / エンドセリン1 / 遺伝子の情報発現と複製 / 細胞周期 / DNA複製 / DNAヘリカーゼ / チェックポイント制御 / MCMタンパク質 / 染色体DNA複製開始 / チェックポイント / 減数分裂期組換え / 乗り越えDNA合成 / 細胞分裂 / 脳発生 / 染色体DNA複製 / リン酸化 / 染色体ダイナミクス / 構造解析 / GM2ガングリオシドーシス / GM2活性化蛋白質 / メタノール資化酵母 / X線結晶構造解析 / 遺伝子変異 / トランスジェニックマウス / バキュロウイルス / 遺伝子解析 / SSCP / alpha-galactosidase / protective protein / galactosialidosis / GM2 gangliosidosis / GM2 activator / Enzyme replacement / α-ガラクトシターゼ / Fadry Disease / Enzyme Replacement Less

グアニン４重鎖(G4)結合蛋白質を用いた機能的G4構造探索・制御技術の開発Principal Investigator
- Principal Investigator
  
  新本美智枝
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Genome biology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Elucidation of DNA replication program in mammalian cells
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Enzyme Replacement Therapy for Fabry Disease :Production of Efficient α-Galactosidase
- Principal Investigator
  
  KASE Ryoichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Studies of the enzyme replacement therapy for Fabry disease
- Principal Investigator
  
  KASE Ryoichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
リソソーム酵素のプロセシング及び分解制御機構とその遺伝病の分子機構の解明
- Principal Investigator
  
  桜庭均
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Partial Overlaping between Protective Protein and Phospholipid Transfer Protein GenesPrincipal Investigator
- Principal Investigator
  
  SHIMMOTO Michie
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C).
- Research Field
  
  Human genetics
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
リソソーム酵素のプロセシング及び分解制御機構とその遺伝病の分子病態の解明
- Principal Investigator
  
  桜庭均
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Structural analysis and molecular designing of enzyme proteins : Its application to clarification of pathology of inherited metabolic diseases and development of therapy
- Principal Investigator
  
  SAKURABA Hitoshi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
多機能性蛋白による糖鎖分解酵素の制御機構とその欠損症の分子病理
- Principal Investigator
  
  桜庭均
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
多機能性蛋白による糖鎖分解酵素の制御機構とその欠損症の分子病理
- Principal Investigator
  
  桜庭均
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
ガラクトシアリドーシスの臨床像と保護蛋白の多機能性に関する研究;変異保護蛋白の性質と細胞内動態Principal Investigator
- Principal Investigator
  
  新本美智枝
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
多機能性蛋白による糖鎖分解酵素の制御機構とその欠損症の分子病理
- Principal Investigator
  
  SAKURABA Hitoshi
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
ガラクトシアリドーシスモデル動物作成のための基礎的研究:マウス保護蛋白ゲノムDNAのクローニングPrincipal Investigator
- Principal Investigator
  
  新本美智枝
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

All 2009 2008

All Journal Article Presentation

[Journal Article] Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast2009
- Author(s)
  Shimmoto, M., Matsumoto, S., Odagiri, Y., Noguchi, E., Russell, P., Masai, H.
- Journal Title
  
  Genes to Cells (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18207009
[Journal Article] Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast.2009
- Author(s)
  Shimmoto, S., Matsumoto, S., Hayano, M., Yokoyama, M., Noguchi, E., Russell, P. and Masai, H
- Journal Title
  
  Genes to Cells in press
  
  Pages: 0-0
- Data Source
  KAKENHI-PROJECT-18207009
[Presentation] Regulation of replication fork in maintenance of genomic integrity2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Michie Shimmoto, Mika Yokoyama, Taku Tanaka, Naoko Kakusho, Naoko Yoshizawa-Sugata, You Zhiying, Sayuri Ito, Chika Taniyama, Ai Ishii
- Organizer
  6th 3R Symposium
- Place of Presentation
  Tsumagoi, Shizuoka
- Data Source
  KAKENHI-PROJECT-18207009
[Presentation] Regula tion of replication fork integrity during S phase.2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michie Shinmoto, Naoko Kakusho, Naoko Yoshizawa and Taku Tanaka
- Organizer
  BMB2008
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-18207009
[Presentation] Regulation of replication fork integrity during S phase2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michiyo Shimmoto, Naoko Kakusho, Naoko Yoshizawa, Taku Tanaka
- Organizer
  BMB (Biochemistry and Molecular Biology) 2008
- Place of Presentation
  神戸ポートアイランド(シンポジウム)
- Data Source
  KAKENHI-PROJECT-18207009
[Presentation] Regulation of establishment and maintenance of replication fork by Cdc7 kinase2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Naoko Kakusho, Michiyo Shimmoto, Mika Yokoyama, Yutaka Kanoh, Taku Tanaka, Yukari Odagiri
- Organizer
  Ataxia-Telangiectasia Workshop
- Place of Presentation
  Ohtsu Prince Hotel at Lake Biwa
- Data Source
  KAKENHI-PROJECT-18207009

1. SAKURABA Hitoshi (60114493)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. ITOH Kohji (00184656)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. KASE Ryoichi (20150203)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MIYATAKE Syouitirou (30239420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MASAI Hisao (40229349)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. YOSHIZAWA Naoko (30344071)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TAKAI Yuko (90332270)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. MATSUMOTO Seiji (40190532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
9. MORIYAMA Kenji (00250217)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. ISHII Ai (80124436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. TANAKA Taku (80425686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KANO Yutaka (90450593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ODA Masako (50399474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ITO Sayuri (60462777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HAYANO Motoshi (30593644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KAKUSHO Naoko (30599593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 須賀田直子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

SHINMOTO Michie 新本 美智枝

SHINMOTO Micie 新本 美智枝

SHIMMOTO Michie 新本 美智枝

Research Projects

Research Products

Co-Researchers

グアニン４重鎖(G4)結合蛋白質を用いた機能的G4構造探索・制御技術の開発Principal Investigator

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Partial Overlaping between Protective Protein and Phospholipid Transfer Protein GenesPrincipal Investigator

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ガラクトシアリドーシスの臨床像と保護蛋白の多機能性に関する研究;変異保護蛋白の性質と細胞内動態Principal Investigator

Principal Investigator

Project Period (FY)

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Principal Investigator

Project Period (FY)

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ガラクトシアリドーシスモデル動物作成のための基礎的研究:マウス保護蛋白ゲノムDNAのクローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast2009

Author(s)

Journal Title

Data Source

[Journal Article] Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast.2009

SHINMOTO Michie 新本美智枝

SHINMOTO Micie 新本美智枝

SHIMMOTO Michie 新本美智枝