Zhiying You ＺｈｉｙｉｎｇＹｏｕ

… Alternative Names

ZHIYING You Zhiying You

TAKAI Yuko 高井裕子

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Researcher Number	90332270
Affiliation (Current)	2022: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員
Affiliation (based on the past Project Information) *help	2020: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員 2018 – 2019: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 主席研究員 2014: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 主席研究員 2011: 財団法人東京都医学総合研究所, ゲノム医科学研究分野, 主任研究員 2010: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 … More 2008 – 2009: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 2007 – 2008: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 2007: 東京都臨床医学総合研究所, 主任研究員 2006: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主席研究員 2004 – 2006: Tokyo Metropolitan Institute of Medical Science, Genome Dynamics Project, Senior Researcher, 東京都臨床医学総合研究所, 主任研究員 2002 – 2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 2003: 財団法人東京都医学研究機構, 主任研究員 2001: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Functional biochemistry / Functional biochemistry / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Functional biochemistry / Molecular biology / Functional biochemistry
Keywords	Principal Investigator DNA複製 / 複製フォーク / DNAヘリカーゼ / DNA結合活性 / MCMヘリカーゼ / Cdt1 / MCM(Minichromosome maintenance) / ATPase / MCM / 酵素の作用機作と調節 … More / ATP結合活性 / MCM結合蛋白 / DNA結合 / processivity / フォーク構造 / MCM (Minichromosome maintenance) / 複製起点 / ヘリカーゼとDNA結合活性 / Cdt1タンパク質 / DnaB・DnaC複合体 / ATP結合活 / プライマーゼ / Cdtlタンパク質 / DNA Replication / MCM Helicase / Cdt1 Protein / Replication Fork / MCM Binding-protein / DNA-binding Activity / Claspin / フォーク安定化 / タンパク質のリン酸化 / 分子内結合 / DNA replication / DNA-binding / phosphorylation / de-phosphorylation / MCM helicase / MCM2-7 / Cdc7キナーゼ / リン酸化 … More Except Principal Investigator 細胞周期 / 複製起点 / 複製タイミング / Cdc7キナーゼ / Epstein Barr Virus / preRC / oriP / 遺伝子の情報発現と複製 / DNA複製 / DNAヘリカーゼ / チェックポイント制御 / MCMタンパク質 / 染色体DNA複製開始 / チェックポイント / 減数分裂期組換え / 乗り越えDNA合成 / 細胞分裂 / 脳発生 / 染色体DNA複製 / リン酸化 / 染色体ダイナミクス / 構造解析 / in vitro DNA 複製 / MCM複合体 / ORC複合体 / EBNAタンパク質 / Epstein Brrr Virus / in viitro DNA複製 / in vitro DNA複製 / in vitro DNA replication / MCM complex / ORC complex / EBNA1 protein / cell cycle Less

Investigation of the regulation mechanism of the replication fork by phosphorylation and intramolecular interaction of ClaspinPrincipal Investigator
- Principal Investigator
  
  ZHIYING You
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Molecular analysis and regulation of replication fork complex, especially focus on MCM helicasePrincipal Investigator
- Principal Investigator
  
  ZHIYING You
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  財団法人東京都医学総合研究所
   Tokyo Metropolitan Organization for Medical Research
Enzymatic analysis of the chromosome replication regulation by MCM helicase complexPrincipal Investigator
- Principal Investigator
  
  ZHIYING You
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Elucidation of DNA replication program in mammalian cells
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Regulatory Mechanism of Activation of MCM Helicase in DNA Replication InitiationPrincipal Investigator
- Principal Investigator
  
  YOU Zhiying
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
染色体DNA複製開始機構の制御-リン酸化によるMCM複合体の活性化と不活性化Principal Investigator
- Principal Investigator
  
  高井裕子 (ZHIYING You)
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Enzymatic analyses of eukaryotic chromosomal DNA replication using the Epstein Barr Virus-derived oriP replicon
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
マウス及び出芽酵母MCM蛋白質の生化学の研究Principal Investigator
- Principal Investigator
  
  高井裕子 (ZHIYING You)
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Book] UV クロスリンキング法" 実験医学別册「分子間相互作用解析バンドブック」192007
- Author(s)
  Zhiying You, 正井久雄
- Data Source
  KAKENHI-PROJECT-19570145
[Book] "UVクロスリンキング法"「分子間相互作用解析ハンドブック」2007
- Author(s)
  You Zhiying、正井久雄
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18207009
[Book] "MCMタンパク質のDNAZ複製における役割"実験医学増刊号「染色体サイクル」2007
- Author(s)
  Zhiying You, 正井久雄
- Total Pages
  219
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18207009
[Book] "MCMタンパク質のDNA複製における役割"実験医学増刊号「染色体サイクル」2007
- Author(s)
  You Zhiying、正井久雄
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18207009
[Book] 2007)"MCMタンパク質のDNA複製における役割" 実験医学増刊号「染色体サイクル」2007
- Author(s)
  You Zhiying, 正井久雄
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18207009
[Book] "MCMタンパク質のDNA複製における役割" 実験医学増刊号「染色体サイクル」252007
- Author(s)
  Zhiying You, 正井久雄
- Data Source
  KAKENHI-PROJECT-19570145
[Book] "UVクロスリンキング法" 「分子間相互作用解析ハンドブック」2007
- Author(s)
  You Zhiying、正井久雄
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18207009
[Journal Article] "Analysis of epigenetic stability and conversions in Saccharomyces cerevisiae reveals a novel role of CAF-I in position-effect variegation."2013
- Author(s)
  Jeffery, D.C., Wyse, B.A., Rehman, M.A., Brown, G.W., You, Z., Oshidari, R., Masai, H. and Yankulov, K.Y.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 41 Pages: 8475-8488
- DOI
  10.1093/nar/gkt623
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23247031, KAKENHI-PROJECT-23657081, KAKENHI-PUBLICLY-24114520, KAKENHI-PUBLICLY-25125724, KAKENHI-PROJECT-25650014
[Journal Article] Purification of replication factors using insect and mammalian cell expression systems2012
- Author(s)
  Uno, S., You, Z., and Masai, H.
- Journal Title
  
  Methods
  
  Volume: 57 Pages: 214-221
- DOI
  10.1016/j.ymeth.2012.06.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23247031, KAKENHI-PROJECT-23657081, KAKENHI-PUBLICLY-24114520
[Journal Article] Fission yeast Swi1-Swi3 complex facilitates DNA binding of Mrc12010
- Author(s)
  Tanaka T, Yokoyama M, Matsumoto S, Fukatsu R, You Z, Masai H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 39609-39622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570156
[Journal Article] Eukaryotic Chromosome DNA Replication : Where, When, and How?2010
- Author(s)
  Hisao Masai, Seji Matsumoto, Zhiying You, Naoko Yoshizawa-Sugata, Masako Oda
- Journal Title
  
  Annu. Rev. Biochem
  
  Volume: 79 Pages: 89-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570156
[Journal Article] Eukaryotic Chromosome DNA Replication : Where, When, and How?2010
- Author(s)
  Masai H, Matsumoto S, You Z, Yoshizawa-Sugata N, Oda M.
- Journal Title
  
  Annu.Rev.Biochem.
  
  Volume: 79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570156
[Journal Article] Eukaryotic Chromosome DNA Replication : Where, When, and How?2010
- Author(s)
  Masai H, Matsumoto S, You Z, Yoshizawa-Sugata N, Oda M.
- Journal Title
  
  Annu Rev Biochem. 79(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570156
[Journal Article] Fission yeast Swi1-Swi3 complex facilitates DNA binding of Mrc12010
- Author(s)
  Taku Tanaka, Mika Yokoyama, Seji Matsumoto, Rino Fukatsu, Zhiying You, Hisao Masai
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 39609-39622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570156
[Journal Article] Cdt1 forms a complex with MCM andactivates its helicase activity.2008
- Author(s)
  Zhiying, Y. and Masai, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 24469-24477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18207009
[Journal Article] Cdt1 forms a complex with the minichromosome maintenance protein (MCM) and activates its helicase activity2008
- Author(s)
  Zhiying You, Hisao Masai
- Journal Title
  
  J Biol. Chem. 283
  
  Pages: 24469-24477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570145
[Journal Article] Cdt1 forms a complex with MCM and activates its helicase activity2008
- Author(s)
  You Z, Masai, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 24469-24477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18207009
[Journal Article] MCMタンパク質のDNA複製における役割2007
- Author(s)
  Zhiying You, 正井久雄
- Journal Title
  
  実験医学 Vol.25・No.5
  
  Pages: 609-613
- Data Source
  KAKENHI-PROJECT-17570124
[Journal Article] MCMタンパク質のDNA複製における役割2007
- Author(s)
  Zhiying You, 正井久雄
- Journal Title
  
  実験医学増刊号「染色体サイクル」 25
  
  Pages: 609-613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570145
[Journal Article] MCMタンパク質のDNA複製における役割2007
- Author(s)
  Zhiying You, 正井久雄
- Journal Title
  
  実験医学 Vol.25・N0.5
  
  Pages: 609-613
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570124
[Journal Article] The role of MCM protein in DNA replication.2007
- Author(s)
  Zhiying You, Hisao Masai.
- Journal Title
  
  Experimental Medicine. Vol.25・No.5
  
  Pages: 609-613
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570124
[Journal Article] UVクロスリンキング法2007
- Author(s)
  Zhiying You, 正井久雄
- Journal Title
  
  実験医学別册「分子間相互作用解析バンドブック」 19
  
  Pages: 164-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570145
[Journal Article] Control of DNA replication : regulation and activation of eukaryotic replicative helicase, MCM.2005
- Author(s)
  Hisao Masai, Zhiying You, Arai Kenichi
- Journal Title
  
  IUBMB Life. 57(4-5)
  
  Pages: 323-335
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570124
[Journal Article] Control of DNA replication : regulation and activation of eukaryotic replicative helicase, MCM.2005
- Author(s)
  Hisao Masai, Zhiying You, Arai Kenichi.
- Journal Title
  
  IUBMB Life. Vol 57(4-5)
  
  Pages: 323-335
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570124
[Journal Article] DNA binding and helicase actions of mouse MCM4/6/7 helicase.2005
- Author(s)
  Zhiying You, Hisao Masai
- Journal Title
  
  Nucleic Acids Research. 33
  
  Pages: 3033-3047
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570124
[Journal Article] DNA binding and helicase actions of mouse MCM4/6/7 helicase.2005
- Author(s)
  Zhiying You, Hisao Masai.
- Journal Title
  
  Nucleic Acids Research. Vol 33
  
  Pages: 3033-3047
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570124
[Journal Article] Thymine-rich single-stranded DNA sequences specifically active mouse Mcm4/6/7 helicase on Y-fork and bubble-like substrates.2003
- Author(s)
  Zhiying You, Yukio Ishimi, Takeshi Mizuno, Kaoru Sugasawa, Fumio Hanaoka, Hisao Masai.
- Journal Title
  
  EMBO J. 22
  
  Pages: 6148-6160
- Data Source
  KAKENHI-PROJECT-15770092
[Journal Article] Roles of Mcm7 and Mcm4 subunits in DNA helicase activity of mouse Mcm4/6/7 complex.2002
- Author(s)
  Zhiying You, Yukio Ishimi, Fumio Hanaoka, Hisao Masai
- Journal Title
  
  J.Biol.Chem. 277
  
  Pages: 42471-42479
- Data Source
  KAKENHI-PROJECT-15770092
[Journal Article] Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity.2002
- Author(s)
  Ken-ichiro Yanagi, Takeshi Mizuno, Zhiying You, Fumio Hanaoka.
- Journal Title
  
  J.Biol.Chem. 277
  
  Pages: 40871-40880
- Data Source
  KAKENHI-PROJECT-15770092
[Journal Article] Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of cdks and cdc7 and that of a critical threonine residue of cdc7 by cdks.2000
- Author(s)
  Hisao Masai, Etsuko Matsui, Zhiying You, Yukio Ishimi, Katsuyuki Tamai, Ken-ichi Arai
- Journal Title
  
  J.Biol.Chem. 275
  
  Pages: 29042-29052
- Data Source
  KAKENHI-PROJECT-15770092
[Journal Article] Inhibition of Mcm4,6,7 hilicase activity by phosphorylation with cyclinA Cdk2.2000
- Author(s)
  Yukio Ishimi, Yuki Komamura-K., Zhiying You, Akira Omori, Masatoshi Kitagawa.
- Journal Title
  
  J.Biol.Chem. 275
  
  Pages: 16235-16241
- Data Source
  KAKENHI-PROJECT-15770092
[Journal Article] Biochemical analysis of the intrinsic Mcm4-Mcm6-Mcm7 DNA hilicase activity.1999
- Author(s)
  Zhiying You, Yuki Komamura, Yukio Ishimi.
- Journal Title
  
  Mol.Cell.Biol. 19
  
  Pages: 8003-8015
- Data Source
  KAKENHI-PROJECT-15770092
[Presentation] DNA複製制御におけるリン酸化によるClaspinの分子内相互作用の調節2020
- Author(s)
  ○Zhiying You 1, Chi-Chun Yang 1, Hisao Masai1
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06124
[Presentation] DNA複製制御におけるClaspinの分子内相互作用の役割 Roles of the intramoleular interaction of Claspin in regulation of DNA replication2019
- Author(s)
  Zhiying You 、Chi-Chun Yang 、Hisao Masai
- Organizer
  第４２回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06124
[Presentation] Biochemistry of Mcm, the central factor for DNA replication: a hetero-hexameric helicase core complex that does not show DNA helicase activity”2018
- Author(s)
  Zhiying You
- Organizer
  首都大学東京Bio-Conference2018
- Invited
- Data Source
  KAKENHI-PROJECT-18K06124
[Presentation] The intramolecular interaction mechanism of human Claspin activation2018
- Author(s)
  Zhiying You 、Chi-Chun Yang 、Hisao Masai
- Organizer
  DNA metabolism, Genomic Stablity & Human Disease Meeting（Cold Spring Harbor, Asia）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06124
[Presentation] Biochemical Characterization of MCM, the Essential DNA Helicase for Eukaryotic DNA Replication2012
- Author(s)
  Zhiying You
- Organizer
  The 3^<rd> Japan-Korea Joint Symposium on life Science
- Place of Presentation
  Tokyo Metropolitan Institute of Medical Science
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] Biochemical Characterization of MCM, the Essential DNA Helicase for Eukaryotic DNA Replication2012
- Author(s)
  Zhiying You
- Organizer
  The 3^<rd> Japan-Korea Joint Symposium on life Science
- Place of Presentation
  Tokyo Metropolitan Institute of Medical Science. Oral presentation
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] MCM複合体によるDNAプライマーゼ活性の促進2011
- Author(s)
  Zhiying You, Sara De Falco, Francesca M. Pisani,正井久雄
- Organizer
  第21回DNA複製・組換え・ゲノム安定性制御ワークショップ
- Place of Presentation
  サンピア福岡
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] Characterization of MCM Loading Factor Cdt1 : similarity between Cdt1 and DnaC proteins2009
- Author(s)
  Zhiying You and Hisao Masai
- Organizer
  The 21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Shanghai, China
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] DNA binding properties of fission yeast fork stabilizing proteins : stimulation of DNA binding of Mrc1 by Swi1/3 complex2009
- Author(s)
  Tanaka, T., Yokoyama, M., You, Z., Fukatsu, R., Masai, H.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] ATP Binding Properties of Mouse CDT1 Protein2009
- Author(s)
  You, Z., Masai, H.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] Actions of Mcm helicase and fork stabilizing factors at replication forks2009
- Author(s)
  Masai, H., You, Z., Tanaka, T., Yokoyama, M.
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] Purification and Biochemical analysis of replication factor Claspin2009
- Author(s)
  Uno, S., You, Z., Kakusho, N., Masai, H.
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] Functional Characterization of Atypical ATP-binding Motif of CDT12009
- Author(s)
  You, Z., Masai, H.
- Organizer
  Cold Spring Harbor Laboratory Meetings
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] EBNA1-dependent association of mammalian pre-RC components with oriP of Epstein-Barr Virus in vitro2009
- Author(s)
  森山賢治, 高井裕子, 正井久雄
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21570156
[Presentation] Cdt1はMCMヘリカーゼと複合体を形成し,そのヘリカーゼ活性を促進する2008
- Author(s)
  Zhiying You
- Organizer
  第19回DNA複製・分配ワークショプ
- Place of Presentation
  静岡県伊豆市・ラフォーレ修善寺
- Data Source
  KAKENHI-PROJECT-19570145
[Presentation] Cdt1はMCMヘリカーゼと複合体を形成し,そのヘリカーゼ活性を促進する2008
- Author(s)
  Zhiying You
- Organizer
  第19回DNA複製・分配ワークショプ
- Place of Presentation
  静岡県伊豆市・ラフォーレ修善寺(oral)
- Data Source
  KAKENHI-PROJECT-19570145
[Presentation] Cdt1 forms a complex with MCM and activates its helicase activity2008
- Author(s)
  Zhiying You, Hisao Masai
- Organizer
  EMBO Conference on“Replication & Segregation of Chromosomes"
- Place of Presentation
  Geilo, Norway
- Data Source
  KAKENHI-PROJECT-19570145
[Presentation] Cdt1 forms a complex with MCM and activates its helicase activity2008
- Author(s)
  Zhiying You and Hisao Masai
- Organizer
  EMBO Conference on "Replication & Segregation of Chromosomes"
- Place of Presentation
  Geilo, Norway
- Data Source
  KAKENHI-PROJECT-19570145
[Presentation] Interaction of Mcm complexes with Cdt1 protein : Effect of Cdt1 on Mcm helicase activity2008
- Author(s)
  Zhiying You, Hisao Masai
- Organizer
  3R (Replication, Recombination, Repair) symposium
- Place of Presentation
  Tsumagoi, Shizuoka
- Data Source
  KAKENHI-PROJECT-19570145
[Presentation] EBウィルス oriP上への無細胞系pre-RC構築2008
- Author(s)
  森山賢治, 高井裕子, 正井久雄
- Organizer
  日本分子生物学会(BMB)2008
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19570145
[Presentation] クランプローダー複合体とMCMサブ複合体の相互作用解析2008
- Author(s)
  谷口莉菜, Zhiying You, 正井久雄, 釣本敏樹
- Organizer
  日本分子生物学会(BMB)2008
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19570145
[Presentation] Interaction of Mcm complexes with Cdt1 protein : Effect of Cdt1 on Mcm helicase activity2008
- Author(s)
  Zhiying You and Hisao Masai
- Organizer
  6th 3R (Replication, Recombination, Repair) symposium
- Place of Presentation
  Tsumagoi, Shizuoka
- Data Source
  KAKENHI-PROJECT-19570145
[Presentation] EBウィルス oriP 上への無細胞系 pre-RC 構築2008
- Author(s)
  森山賢治, 高井裕子, 正井久雄
- Organizer
  日本分子生物学会(BMB)2008
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19570145
[Presentation] Regulation of replication fork in maintenance of genomic integrity2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Michie Shimmoto, Mika Yokoyama, Taku Tanaka, Naoko Kakusho, Naoko Yoshizawa-Sugata, You Zhiying, Sayuri Ito, Chika Taniyama, Ai Ishii
- Organizer
  6th 3R Symposium
- Place of Presentation
  Tsumagoi, Shizuoka
- Data Source
  KAKENHI-PROJECT-18207009

1. YOSHIZAWA Naoko (30344071)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. MASAI Hisao (40229349)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
3. MORIYAMA Kenji (00250217)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SHINMOTO Micie (20216237)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. MIYATAKE Syouitirou (30239420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MATSUMOTO Seiji (40190532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. ISHII Ai (80124436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. TANAKA Taku (80425686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KANO Yutaka (90450593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ODA Masako (50399474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITO Sayuri (60462777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HAYANO Motoshi (30593644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAKUSHO Naoko (30599593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TSURIMOTO Toshiki (30163885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SIRAKATA Masaki (70251551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TAMAI Katsuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Zhiying You Ｚｈｉｙｉｎｇ Ｙｏｕ

ZHIYING You Zhiying You

TAKAI Yuko 高井 裕子

Research Projects

Research Products

Co-Researchers

Investigation of the regulation mechanism of the replication fork by phosphorylation and intramolecular interaction of ClaspinPrincipal Investigator

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Review Section

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Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication

Principal Investigator

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Molecular analysis and regulation of replication fork complex, especially focus on MCM helicasePrincipal Investigator

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Enzymatic analysis of the chromosome replication regulation by MCM helicase complexPrincipal Investigator

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Elucidation of DNA replication program in mammalian cells

Principal Investigator

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Regulatory Mechanism of Activation of MCM Helicase in DNA Replication InitiationPrincipal Investigator

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染色体DNA複製開始機構の制御-リン酸化によるMCM複合体の活性化と不活性化Principal Investigator

Principal Investigator

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Enzymatic analyses of eukaryotic chromosomal DNA replication using the Epstein Barr Virus-derived oriP replicon

Principal Investigator

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マウス及び出芽酵母MCM蛋白質の生化学の研究Principal Investigator

Principal Investigator

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Research Institution

[Book] UV クロスリンキング法" 実験医学別册「分子間相互作用解析バンドブック」192007

Author(s)

Data Source

[Book] "UVクロスリンキング法"「分子間相互作用解析ハンドブック」2007

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Total Pages

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[Book] "MCMタンパク質のDNAZ複製における役割"実験医学 増刊号「染色体サイクル」2007

Author(s)

Total Pages

Publisher

Data Source

[Book] "MCMタンパク質のDNA複製における役割"実験医学増刊号「染色体サイクル」2007

Author(s)

Total Pages

Publisher

Data Source

[Book] 2007)"MCMタンパク質のDNA複製における役割" 実験医学増刊号「染色体サイクル」2007

Author(s)

Zhiying You ＺｈｉｙｉｎｇＹｏｕ

TAKAI Yuko 高井裕子

[Book] "MCMタンパク質のDNAZ複製における役割"実験医学増刊号「染色体サイクル」2007