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KIMOTO Hiroshi  木元 博史

ORCIDConnect your ORCID iD *help
Researcher Number 20225080
Affiliation (based on the past Project Information) *help 1993 – 1995: 国立予防衛生研究所, 免疫部, 研究員
1991: NIH, Dep. Cell. Immunol., Researcher, 細胞免疫部, 研究員
1991: 国立予防衛生研究所, 細胞免疫部, 研究官
Review Section/Research Field
Principal Investigator
Immunology
Except Principal Investigator
Immunology
Keywords
Principal Investigator
mice lacking Vpre-B3 (8HS-20) gene / surrogate loght chain / gene targeting / T dependent antigen / Vper-B1 / lambda 5 / mu chain complex / B cell differentiation / 脾臓 / 骨髄 … More / FACS / 免疫応答 / 分化 / 遺伝子ターゲッティング / pre B細胞 / T依存性免疫応答 / 細胞分化 / Dμ蛋白 / Vpre-B3 / B細胞 / Vpre-B3欠損マウス / 代替L鎖 / 遺伝子欠損マウス / T依存性抗原 / Vpre-B1 / λ5 / μ鎖複合体 / B細胞分化 / マスト細胞 / マクロファ-ジ / 単離精製 / 多能性分化能 / 幼若造血細胞 / 胎児胸腺 / 温度感受性変異株 / Abelsonマウス白血病ウィルス … More
Except Principal Investigator
細胞周期 / CD40 / CD43 / トランスジェニックマウス / B細胞 / circular DNA / V_H gene replacement / MAPキナーゼ / 高親和性B細胞 / 体細胞超変異 / 体細胞点変異 / VpreB-3 / antigen presentation / somatic hypermutation / cell cycle / germinal center / TRAF / MAP kinase / primary follicles / 免疫グロブリン遺伝子 / 記憶Bリンパ球 / centrocyte / Bリンパ球 / centroblast / 一次免疫反応 / 抗原提示機能 / 細胞増殖 / 胚中心 / 一次濾胞B細胞 / B cell dynamics / lgG antibodies / lgM antibodies / immune response / CD43 transgenic mice / cell cycle regulation / B cell survival / 細胞生存維持 / Cre-loxPシステム / CD43ゲノム遺伝子 / ターゲッティング / ホモ遺伝子強発現マウス / IgMb抗体産生 / CD43強発現マウス / 細胞内相互作用 / B細胞dynamics / IgG抗体産生 / IgM抗体産生 / 免疫反応 / CD43トランスジェニックマウス / 細胞周期調節 / B細胞生存維持 / mu chain transport / lg gene super family / surrogate L chains / B cell specific gene / mu chain expression / B cell maturation / virgin B細胞 / 前B細胞 / μ鎖複合体 / シグナル伝達 / Macー1陽性細胞 / CD45R / μ鎖輸送 / μ鎖発現 / B細胞成熟 / Ig gene superfamily / 幼若B細胞特異的遺伝子 / B7-2 / error prone DNA repair / V_H遺伝子 / 胚中心B細胞 / 代替L鎖 / 記憶細胞 / Germinal Center(胚中心) / 遺伝子欠損マウス / CD43レセプター / mu鎖代替L鎖複合体 / 分化・成熟 Less
  • Research Projects

    (8 results)
  • Co-Researchers

    (11 People)
  •  B細胞分化・成熟分子機構の解明及びその制御

    • Principal Investigator
      竹森 利忠
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所
  •  Mechanism of B cell maturaion

    • Principal Investigator
      TAKEMORI Toshitada
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      National Institute of Health
  •  B細胞分化・成熟分子機構の解明およびその制御

    • Principal Investigator
      竹森 利忠
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所
  •  Functional role of CD43 in immune system

    • Principal Investigator
      NAGAOKA Hitoshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      National Institute of Health of Japan
  •  Analysis of mutant mice lacking Vpre-B3 (8HS-20) gene encoding a third surrogate light chair.Principal Investigator

    • Principal Investigator
      KIMOTO Hiroshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      National Institute of Health ofJapan
  •  B細胞分化・成熟分子機構の解明およびその制御

    • Principal Investigator
      竹森 利忠
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所
  •  胎児胸腺由来幼若造血幹細胞の純化とその株化及びその多能性分化能の解析Principal Investigator

    • Principal Investigator
      木元 博史
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所
  •  The analysis of B cell differentiation and maturation

    • Principal Investigator
      TAKEMORI Toshitada
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      National Institute of Health
  • 1.  TAKEMORI Toshitada (60114295)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  TOKUHISA Takeshi (20134364)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  NAGAOKA Hitoshi (20270647)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  MISAWA Yukiko (10250185)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KASIWADA Masaki (20270639)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  谷山 忠義 (20136609)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  横田 恭子 (20182701)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MIZUGUCHI Junichiro (20150188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OHNISHI Kazuo (90169011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  重本 和宏 (00192104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ADACHI Yoshihiro (20291122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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