Mizuguchi Junichiro 水口純一郎

… Alternative Names

MIZUGUCHI Junichiro 水口純一郎

MAZUGUCHI Junichiro 水口純一郎

Less

Researcher Number	20150188
Other IDs
External Links
Affiliation (Current)	2025: 東京医科大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help	2016 – 2017: 東京医科大学, その他部局等, 名誉教授 2015: 東京医科大学, その他, 名誉教授 2009 – 2014: Tokyo Medical University, 医学部, 教授 2000 – 2007: 東京医科大学, 医学部, 教授 1995 – 1997: 東京医科大学, 教授 … More 1993 – 1994: 東京医科大学, 医学部, 教授 1991: NIH, Dep. Immunol., Head, 体液性免疫部, 室長 1990: 国立予防衛生研究所, 体液性免疫, 室長 Less
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / Surgical dentistry / 病態科学系歯学(含放射線系歯学) / Immunology Except Principal Investigator Biophysics / Immunology / Biomedical engineering/Biomaterial science and engineering / Surgical dentistry
Keywords	Principal Investigator 口腔扁平上皮癌 / TRAIL / apoptosis / squamous cell carcinoma / アポトーシス / カルボプラチン / CD21 / 扁平上皮癌 / 癌幹細胞 / Microarray … More / Gene / Tumor / Odontologv / マイクロアレイ / 遺伝子 / 癌 / 歯学 / Bcl-2 family proteins / new treatment modality / chemotherapeutic agents / 併用療法 / Bax-α / 難治性悪性腫瘍 / Bcl2ファミリータンパク質 / 化学療法剤抵抗性 / Bcl-2ファミリータンパク質 / 新規治療法 / 化学療法剤 / Drug-Resistance / Caspase-3 / Bcl-xL / Caboplatin / 薬剤耐性 / カスペース3 / Bcl-x_L / signal transduction / phosphorylation / B cell / チロシンキナーゼ / ヒトB細胞 / 補体受容体2 / シグナル伝達 / リン酸化 / B細胞 / 転移 / 炎症 / 治療戦略 … More Except Principal Investigator IL-12 / STAT3 / STAT1 / IL-27 / Sphingosine Kinase 2 / circular DNA / V_H gene replacement / Proliferation / IFN-γ Production / IL-12 Receptorβ1 / Yeast Two-Hybrid / CD8+T細胞 / 抗腫瘍効果 / IFN-γ / 細胞増殖 / IFN-γ産生 / IL-12レセプターβ1 / Plasmid DNA / DNA complex / Liposome / Atomic force microscopy / Antisense DNA / Zeta potential / Cationic cholesterol / Gene transfection / Cationic liposomes / アンチセンス / プラスミド / アンチロンスDNA / リポソーム / 遺伝子導入 / ゼータ電位 / ベクターの開発 / エンドサイトーシス / 原子間力顕微鏡 / 共焦点レーザ顕微鏡 / 正電荷リポソーム / 正電荷コレステロール / 遺伝子治療 / calcium ion / cis-trans isomerization / antigen-presenting cell / immune response / T cell / photocontrol / antigen-antibody reaction / photochromic antigen / 細胞内カルシウムイオン / 免疫リポソーム / 抗体 / アゾベンゼン / T細胞レセプター / フォトクロミック分子 / 抗原抗体反応光制御 / カルシウムイオン / シス・トランス異性化反応 / 抗原提示細胞 / 免疫応答 / T細胞 / 光制御 / 抗原抗体反応 / フォトクロミック抗原 / mu chain transport / lg gene super family / surrogate L chains / B cell specific gene / mu chain expression / B cell maturation / virgin B細胞 / 前B細胞 / μ鎖複合体 / シグナル伝達 / Macー1陽性細胞 / CD45R / トランスジェニックマウス / μ鎖輸送 / μ鎖発現 / B細胞成熟 / Ig gene superfamily / 幼若B細胞特異的遺伝子 / CTL / がんワクチン / ナノテクノロジー / 樹状細胞 / ナノ粒子 / ガンワクチン / COX-2 / PTH / 顎骨浸潤 / 口腔癌 Less

Control of antigen-specific immune response by nanoparticles and elucidation of its cellular mechanism
- Principal Investigator
  
  Yanase Noriko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical University
Role of inflammation in the initiation and development of oral squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  MIZUGUCHI Junichiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Medical University
A research for new treatment with parathyroid hormone and cyclooxygenase-2 for mandibular bone invasion by oral squamous cell carcinoma
- Principal Investigator
  
  SATOMI TAKAFUMI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical University
Characterization of cancer stem cells for oral squamous cell carcinoma cells and its application for treatment of oral carcinomaPrincipal Investigator
- Principal Investigator
  
  MIZUGUCHI Junichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical University
Comprehensive genome-wide assessment of gene a qn ssion involved in tumor development and metastasis with the goal of clinical application.Principal Investigator
- Principal Investigator
  
  MIZUGUCHI Junitiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical University
Therapeutic Strategy for Squamous Cell Carcinoma Resistant to Chemotherapeutic AgentsPrincipal Investigator
- Principal Investigator
  
  MIZUGUCHI Junichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Medical University
Studies on the signal transduction passways through IL-12 receptor
- Principal Investigator
  
  YOSHIMOTO Takayuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical University
CISPLATIN-INDUCED APOPTOSIS AGAINST SQUAMOUS CELL CARCINOMA CELLSPrincipal Investigator
- Principal Investigator
  
  MAZUGUCHI Junichiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Tokyo Medical University
Study for gene transfection and intracellular distribution of transfected DNA.
- Principal Investigator
  
  NAKANISHI Mamoru
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya City University
Photocontrolled Immune Responses using Photochromic Antigen
- Principal Investigator
  
  NAKANISHI Mamoru
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya City University
Role of tyrosine kinase on signal transduction through complement receptor 2 (CD21)Principal Investigator
- Principal Investigator
  
  MIZUGUCHI Junichiro
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical College
The analysis of B cell differentiation and maturation
- Principal Investigator
  
  TAKEMORI Toshitada
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  National Institute of Health

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] 臨床免疫44 「B細胞の生存維持とBcl-2ファミリー」2005
- Author(s)
  高田栄子, 水口純一郎
- Publisher
  科学評論社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Vaccination with OVA-bound nanoparticles enhancing IL-7 inhibits the growth of OVA-expressing E.G7 tumor cells in vivo.2015
- Author(s)
  Toyota H, Yanase N, Yoshimoto T, Harada M, Kato Y, and Mizuguchi J
- Journal Title
  
  Onco Rep
  
  Volume: 33 Issue: 1 Pages: 292-6
- DOI
  10.3892/or.2014.3603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592841, KAKENHI-PROJECT-26350516
[Journal Article] Thy28 protects against anti-CD3-mediated thymic cell death in vivo.2015
- Author(s)
  Toyota H, Sudo K, Kojima K, Yanase N, Nagao T, Takahashi RH, Iobe H, Kuwabara T, Kakiuchi T, and Mizuguchi J.
- Journal Title
  
  Apoptosis
  
  Volume: 20 Issue: 4 Pages: 444-54
- DOI
  10.1007/s10495-014-1082-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592841, KAKENHI-PROJECT-25460600
[Journal Article] OVA-bound nanoparticles induce OVA-specific IgG1, IgG2a, and IgG2b responses with low IgE synthesis.2014
- Author(s)
  Yanase N, Toyota H, Yagyu S, Seki T, Harada M, Kato Y, and Mizuguchi J
- Journal Title
  
  Vaccine
  
  Volume: 32 Issue: 45 Pages: 5918-24
- DOI
  10.1016/j.vaccine.2014.08.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592841, KAKENHI-PROJECT-26350516
[Journal Article] Requirement of apoptosis-inducing kinase 1 for the induction of bronchial asthma following stimulation with ovalbumin.2013
- Author(s)
  Takada, E., Furuhata, M., Nakae, S., Ichijo, H., Sudo, K. and Mizuguchi, J.
- Journal Title
  
  Int. Arch. Allergy Immunol.
  
  Volume: 162 Issue: 2 Pages: 104-114
- DOI
  10.1159/000353240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-24592841, KAKENHI-PROJECT-25650061
[Journal Article] IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in the cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner2013
- Author(s)
  Chiba Y, Mizoguchi I, Mitobe K, Higuchi K, Nagai H, Nishigori C, Mizuguchi J, Yoshimoto T
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592841
[Journal Article] Arginine methylation regulates antibody responses through modulating cell division and isotype switching in B cells2013
- Author(s)
  Hata K, Mizuguchi J
- Journal Title
  
  Microbiol Immunol
  
  Volume: 57 Issue: 3 Pages: 185-92
- DOI
  10.1111/1348-0421.12019
- NAID
  40019615133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592841
[Journal Article] Thy28 partially prevents apoptosis induction following engagement of membrane immunoglobulin in WEHI-231 B lymphoma cells.2012
- Author(s)
  Toyota H, Jiang XZ, Asakura H, and Mizuguchi J
- Journal Title
  
  Cell Mol Biol Lett
  
  Volume: 17 Issue: 1 Pages: 36-48
- DOI
  10.2478/s11658-011-0034-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592841
[Journal Article] PKC-delta mediates interferon-alpha-induced apoptosis through c-Jun N-terminal kinase activation.2012
- Author(s)
  Yanase N, Hayashida M, Kanetaka-Naka Y, Hoshika A, and Mizuguchi J
- Journal Title
  
  BMC Cell Biol
  
  Volume: 13 Issue: 1 Pages: 7-15
- DOI
  10.1186/1471-2121-13-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592841
[Journal Article] Thy28 partially prevents apoptosis induction following engagement of membrane immunoglobulin in WEHI-231 B lymphoma cells2012
- Author(s)
  Toyota H, Jiang X, Asakura H, Mizuguchi J
- Journal Title
  
  Cell Mol Biol Lett
  
  Volume: 17 Pages: 36-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] IL-27 suppresses RANKL expression in CD4+ T cells in part through STAT32011
- Author(s)
  Kamiya S, Okumura M, Chiba Y, Fukawa T, Nakamura C, Nimura N, Mizuguchi J, Wada S, Yoshimoto T
- Journal Title
  
  Immunol Lett
  
  Volume: 138 Pages: 47-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Enhanced T cell-independent antibody responses in c-Jun N-terminal kinase 2(JNK2)-deficient B cells following stimulation with CpG-1826 and anti-IgM2010
- Author(s)
  Cao Y, Takada E, Hata K, Sudo K, Furuhata M, Mizuguchi J
- Journal Title
  
  Immunol Lett
  
  Volume: 132 Pages: 38-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article]2010
- Author(s)
  水口純一郎(監修:金井正光)
- Journal Title
  
  臨床検査法提要(第9章免疫血清検査)(金原出版株式会社)
  
  Pages: 711-721
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23, and IL-27.2010
- Author(s)
  Xu M, Mizoguchi I, Morishima N, Chiba Y, Mizuguchi J, Yoshimoto T.
- Journal Title
  
  Clin Dev Immunol
  
  Volume: 2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Interleukins and cancer immunotherapy2009
- Author(s)
  Yoshimoto T, Morishima N, Okuma M, Chiba Y, Xu M, Mizuguchi J
- Journal Title
  
  Immunotherapy1
  
  Volume: 1 Pages: 825-844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] TGF-beta is necessary for induction of IL-23R and Th17 differentiation by IL-6 and IL-232009
- Author(s)
  Morishima N, Mizoguchi I, Takeda K, Mizuguchi J, Yoshimoto T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 386 Pages: 105-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Apoptosis signal-regulating kinase(ASK)-1 mediates apoptosis through activation of JNK1 following enagement of membrane immunoglobulin.2009
- Author(s)
  Furuhata M, Takada E, Noguchi T, Ichijo H.., Mizuguchi J.
- Journal Title
  
  Exp Cell Res 10;315(20)
  
  Pages: 3467-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand induces apoptotic cell death through c-Jun NH2-teriminal kinase activation in squamous cell carcinoma cells2009
- Author(s)
  Noutomi T, Itoh M, Toyota H, Takada E, and Mizuguchi J
- Journal Title
  
  Oncol Rep
  
  Volume: 22 Pages: 1169-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] A double-edged sword in B-cell-targeted therapy for inflammatory diseases2009
- Author(s)
  Mizuguchi J
- Journal Title
  
  Exp Rev. Clin Immunol
  
  Volume: 5 Pages: 283-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] TGF-beta is necessary for induction of 1L23R and Th17 differentiation by 1L-6 and 1L-23.2009
- Author(s)
  Morishima N, Mizoguchi I, Takeda K, Mizuguchi J., Yoshimoto T.
- Journal Title
  
  Biochem Biophys Res Commun 15;180(10)
  
  Pages: 105-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand induces apoptoric cell death through c-Jun NH2-terminal kinase activation in squamous cell carcinoma cells.2009
- Author(s)
  Noutomi T, Itoh M, Toyota H, Takada E., Mizuguchi J.
- Journal Title
  
  Oncol Rep 22(5)
  
  Pages: 1169-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Apoptosis signal-regulating kinase(ASK)-1 mediates apoptosis through activation of JNK1 following engagement of membrane immunoglobulin.2009
- Author(s)
  Furuhata M, Takada E, Noguchi T, Ichijo H, Mizuguchi J
- Journal Title
  
  Exp Cell Res
  
  Volume: 315 Pages: 3467-3476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Interferon-alpha induces transient upregulation of c-FLIP through NF-kappaB activation2008
- Author(s)
  Kanetaka, Y, Hayashida, M, Hoshika, A, Yanase, N, Mizuguchi, J
- Journal Title
  
  Exp Cell Res 314-2(Epub ahead of print)
  
  Pages: 246-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Interferon-alpha induces transient upregulation of c-FLIP through NF-kappaB activation2008
- Author(s)
  Kanetaka Y, Hayashida M, Hoshika A, Yanase N, Mizuguchi J
- Journal Title
  
  Esp Cell Res 314(2)
  
  Pages: 2664-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Interferon-alpha induces transient upregulation of c-FLIP through NF-kappaB activation2008
- Author(s)
  Kanetaka Y, Hayashida M, Hoshika N, Yanase N, Mizuguchi J
- Journal Title
  
  Exp Cell Res 314(2)
  
  Pages: 264-54
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Interferon-alpha-induced apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-dependent and -independent manner2007
- Author(s)
  Yanase N, Kanetaka Y, Mizuguchi J
- Journal Title
  
  Oncol Rep 18(4)
  
  Pages: 1031-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] c-Jun-NH(2)-terminal kinase potentiates apoptotic cell death in response to carboplatin in Blymphoma cells2007
- Author(s)
  Takada E, Hata K, Mizuguchi J
- Journal Title
  
  Cancer Chemother Pharmacol (Epub ahead of print)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Interferon-alpha-induced apoptosis via tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)-dependent and -independent manner2007
- Author(s)
  Yanase N, Kanetaka Y, Mizuguchi J
- Journal Title
  
  Oncol Rep 18(4)
  
  Pages: 1031-8
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] c-Jun-NH2-terminal kinase potentiates apoptotic cell death in response to carboplatin in B lymphoma cells2007
- Author(s)
  Takada, E, Hata, K, Mizuguchi, J
- Journal Title
  
  Cancer Chemother Pharmacol
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] c-Jun-NH(2)-terminal kinase potentiates apoptotic cell death in response to carboplatin in B lymphoma cells2007
- Author(s)
  Takada E, Hata K, Mizuguchi J
- Journal Title
  
  Cancer Chemother Pharmacol (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] IFN-alpha sensitizes daudi B lymphoma cells to anti-IgM induced loss of mitochondrial membrane potential through activation of c-Jun NH(2)-terminal kinase.2006
- Author(s)
  Hayashida, Hoshika, Kanetaka, Yanase, Mizuguchi.
- Journal Title
  
  Journal of interferon ＆ cytokine research 26(6)
  
  Pages: 421-429
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Anticancer effects of phenoxazine derivatives combined with tumor necrosis factor-related apoptosis-inducing ligand on pancreatic cell lines, KLM-1 and MIA-PaCa-2.2006
- Author(s)
  Kato, Shirato, Imaizumi, Toyota, Mizuguchi, Odawara, Che, Akiyama, Abe, Tomodda.
- Journal Title
  
  Oncology Report 15(4)
  
  Pages: 843-848
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Antiangiogenic and antitumor activities of IL-27.2006
- Author(s)
  Shimizu, Shimamura, Owaki, Asakawa, Fujita, Kudo, Iwakura, Takeda, Luster, Mizuguchi, Yoshimoto.
- Journal Title
  
  Jouronal of Immunology 176(12)
  
  Pages: 7317-7324
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Apoptosis induced by chemotherapeutic agents involves c-Jun N-terminal kinase activation in sarcoma cell lines2006
- Author(s)
  Koyama, T, Mikami, T, Koyama, T, Imakiire, A, Yamamoto, K, Toyota, H, Mizuguchi, J
- Journal Title
  
  J Orthop Res 24-6
  
  Pages: 1153-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Requirement for JNK-dependent upregulation of BimL in anti-IgM-induced apoptosis in murine B lymphoma cell lines WEHI-231 and CH31.2006
- Author(s)
  Takada, Hata, Mizuguchi.
- Journal Title
  
  Experimental Cell Research 312(19)
  
  Pages: 3728-3738
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] C-jun N-terminal kinase activation is required for apoptotic cell death induced by TNF-related apoptosis-inducing ligand plus DNA-damaging agents in sarcoma cell lines.2006
- Author(s)
  Mikami, Koyama, Koyama, Imakiire, Yamamoto, Furuhata, Toyota, Mizuguchi.
- Journal Title
  
  Anticancer Research 26(2A)
  
  Pages: 1153-1160
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Apoptosis induced by chemotherapeutic agents involves c-Jun N-terminal kinase activation in sarcoma cell lines.2006
- Author(s)
  Koyama, Mikami, Koyama, Imakiire, Yamamoto, Toyota, Mizuguchi.
- Journal Title
  
  Journal of orthopaedic research 24(6)
  
  Pages: 1153-1162
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] IFN-alpha sensitizes Daudi B lymphoma cells to anti-IgM induced loss of mitochondrial membrane potential through activation of c-Jun NH(2)-terminal kinase2006
- Author(s)
  Hayashida M, Hoshika A, Kanetaka Y, Yanase N, Mizuguchi J.
- Journal Title
  
  J Interferon Cytokine Res 26(6)
  
  Pages: 421-9
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] IFN-alpha sensitizes Daudi B lymphoma cells to anti-IgM induced loss of mitochondrial membrane potential through activation of c-Jun NH_2-Terminal kinase2006
- Author(s)
  Hayashida, M, Hoshika, A, Kanetaka, Y, Yanase, N, Mizuguchi, J
- Journal Title
  
  J Interferon Cytokine Res 26-6
  
  Pages: 421-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] c-Jun-NH2-terminal kinase activation is required for apoptotic cell death induced by TNF-related apoptosis-inducing ligand plus DNA-damaging agents in sarcoma cell lines2006
- Author(s)
  Mikami, T, Koyama, T, Koyama, T, Imakiire, A, Yamamoto, K, Furuhata, M, Toyota, H, Mizuguchi, J
- Journal Title
  
  Anticancer Res 26-2A
  
  Pages: 1153-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Enforced expression of a truncated form of Bax-alpha (tBax) driven by human telomerase reverse transcriptase (fTERT) promoter sensitizes tumor cells to chemotherapeutic agents or tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).2006
- Author(s)
  Toyota, Kondo, Kyo, Mizuguchi.
- Journal Title
  
  Anticancer research 26 (1A)
  
  Pages: 99-105
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Enforced expression of a truncated form of Bax-alpha(tBax)driven by human telomerase reverse transcriptase(hTERT)promoter sensitizes tumor cells to chemotherapeutic agents or tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)2006
- Author(s)
  Toyota H, Kondo S, Kyo S, Mizuguchi J.
- Journal Title
  
  Anticancer Res 26(1A)
  
  Pages: 99-105
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Apoptosis induced by chemotherapeutic agents involves c-Jun N-terminal kinase activation in sarcoma cell lines2006
- Author(s)
  Koyama T, Mikami T, Koyama T, Imakiire A, Yamamoto K, Toyota H, Mizuguchi J.
- Journal Title
  
  J Orthop Res 24(6)
  
  Pages: 1153-62
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Requirement for JNK-dependent upregulation of BimL in anti-IgM-induced apoptosis in murine B lymphoma cell lines WEHI-231 and CH312006
- Author(s)
  Takada E, Hata K, Mizuguchi J.
- Journal Title
  
  Exp Cell Res 312(19)
  
  Pages: 3728-38
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] c-jun N-terminal kinase activation is required for apoptotic cell death induced by TNF-related apoptosis-inducing ligand plus DNA-damaging agents in sarcoma cell lines2006
- Author(s)
  Mikami T, Koyama T, Koyama T, Imakiire A, Yamamoto K, Furuhata M, Toyota H, Mizuguchi J.
- Journal Title
  
  Anticancer Res 26(2A)
  
  Pages: 1153-60
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Enforced expression of a truncated Form ofBax-alpha(tBax)driven by human telomerase reverse transcriptase(hTERT) promoter sensitizes tumor cells to chemotherapeutic agents or tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)2006
- Author(s)
  Toyota, H, Kondo, S, Kyo, S, Mizuguchi, J
- Journal Title
  
  Anticancer Res 26-A
  
  Pages: 99-105
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells2005
- Author(s)
  Takada E, Shimo K, Hata K, Abiake M, Mukai Y, Moriyama M, Heasley L, Mizuguchi J
- Journal Title
  
  Exp Cell Res 304(2)
  
  Pages: 518-30
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Requirement of c-Jun NH2-terminal kinase activation in interferon-alpha-induced apoptosis through upregulation of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)in Daudi B lymphoma cells2005
- Author(s)
  Yanase N, Hata K, Shimo K, Hayashida M, Evers BM, Mizuguchi J
- Journal Title
  
  Exp Cell Res 310(1)
  
  Pages: 10-21
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through upregulation of CD95 in CH31 B lymphoma cells.2005
- Author(s)
  Takada, Shimo, Hata, Aiake, Mukai, Moriyama, Heasley, Mizuguchi.
- Journal Title
  
  Experimental Cell Research 304(2)
  
  Pages: 518-530
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Requirement of c-Jun NH2-terminal kinase activation in interferon-alpha-induced apoptosis through upregulation of tumor necrosis factor * related apoptosis-inducing ligand (TRAIL) in Daudi B lymphoma cells.2005
- Author(s)
  Yanase, Hata, Shimo, Hayashida, Evers, Mizuguchi.
- Journal Title
  
  Experimental Cell Research 310(1)
  
  Pages: 10-21
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Interferon-beta-induced activation of c-Jun NH2- terminal kinase mediates apoptosis through upregulation of CD95 in CH31 B lymphoma cells2005
- Author(s)
  Takada, E, Shimo, K, Hata, K, Abiake, M, Mukai, Y, Moriyama, M, Heasley, L, Mizuguchi, J
- Journal Title
  
  Exp Cell Res 304-2
  
  Pages: 518-530
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Synergistic antitumor effect by coexpression of chemokine CCL21/SLC and costimulatory molecule LIGHT.2004
- Author(s)
  Hisada M, Yoshimoto T, Kamiya S, Magami Y, Miyaji H, Yoneto T, Tamada K, Aoki T, Koyanagi Y, Mizuguchi J.
- Journal Title
  
  Cancer Gene Ther. 11
  
  Pages: 280-288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Potent antitumor activity of interleukin-27.2004
- Author(s)
  Hisada M, Kamiyama S, Fujita K, Belladonna ML, Aoki T, Koyanagi Y, Mizuguchi J, Yoshimoto T.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 1152-1156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] 難治性悪性腫瘍に対するTRAIL分子に対する治療戦略2004
- Author(s)
  矢那瀬紀子, 水口純一郎
- Journal Title
  
  東京医科大学雑誌 39
  
  Pages: 9-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Strategy for treatment of intractable malignant tumors with TNF-related apoptosis-inducing ligand (TRAIL) molecule.2004
- Author(s)
  Yanase N, Mizuguchi J.
- Journal Title
  
  J Tokyo Med Univ. 62
  
  Pages: 9-17
- NAID
  10012079403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Id-3-mediated enhancement of cisplatin-induced apoptosis in a sarcoma cell line MG-63.2004
- Author(s)
  Koyama T, Suzuki H, Imakiire A, Yanase N, Hata K, Mizuguchi J.
- Journal Title
  
  Anticancer Res. 24
  
  Pages: 1519-1524
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Retrovirus-mediated transduction of TRAIL and chemotherapeutic agents co-operatovely induce apoptosis cell death in both sarcoma and myeloma cells.2003
- Author(s)
  Suzuki H, Hotta T, Koyama T, Komagata M, Imakiire A, Yanase N, Yoshimoto T, Mizuguchi J.
- Journal Title
  
  Anticancer Res. 23
  
  Pages: 3247-3253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis-factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential.2003
- Author(s)
  Hotta T, Suzuki H, Nagai S, Yamamoto T, Imakiire A, Takada E, Itoh M, Mizuguchi J.
- Journal Title
  
  J Orthop Res. 21
  
  Pages: 949-957
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Enhanced expression of the apoptosis inducing ligand TRAIL in mononuclear cells after myocardial infarction.2003
- Author(s)
  Nakajima H, Yanase N, Oshima K, Sasame A, Hara T, Fukuzawa S, Takata R, Hara K, Mukai K, Yamashina A, Mizuguchi J.
- Journal Title
  
  Japan Heart J. 44
  
  Pages: 833-844
- NAID
  130000067291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Etoposide-mediated sensitization of squamous cell carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced loss in mitochondrial membrane potential.2003
- Author(s)
  Itoh M, Noutomi T, Toyota H, Mizuguchi J.
- Journal Title
  
  Oral Oncol. 39
  
  Pages: 269-276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Calpain-induced Bax-cleavage product is a more potent inducer of apoptotoc cell death than wild-type Bax.2003
- Author(s)
  Toyota H, Yanase N, Moriyama M, Sudo T, Mizuguchi J.
- Journal Title
  
  Cancer Lett. 189
  
  Pages: 221-230
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Induction of apotosis and/or necrosis following exposure to antitumor agents in a melanoma cell lone, probably through modulation of Bcl-2 family proteins2003
- Author(s)
  Shibuya H, Kato Y, Saito M, Isobe T, Tsuboi R, Koga M, Toyota H, Mizuguchi J.
- Journal Title
  
  Melanoma Res. 13
  
  Pages: 457-464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] c-Jun N-terminal kinase activation is required for apoptotic cell death induced by TNF-related apoptosis-inducing ligand plus DNA-damaging agents in sarcoma cell lines.
- Author(s)
  Mikami, Koyama, Imakiire, Yamamoto, Furuhata, Toyota, Mizuguchi.
- Journal Title
  
  Anticancer Research (In press)
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] A novel micellar nanoparticles functions as an adjuvant to enhance anti-tumor immune responses in vivo2015
- Author(s)
  Yanase Noriko、Toyota　Hiroko, , Harada　Mitsunori, Mizuguchi Junichiro, Hata Kikumi,Yokosuka Takashi
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26350516
[Presentation] Thy28 regulates anti-CD3-induced thymocyte death in vivo2012
- Author(s)
  Toyota H, Yanase N, Mizuguchi J
- Organizer
  Proceedings of the Japanese Society for Immunology
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24592841
[Presentation] EBI3 functions as an adaptor molecule associating with p62/SQSTM1 to regulate the development of colitis in CD4+ T cells2012
- Author(s)
  Mizoguchi I, Mizuguchi J, Yoshimoto T
- Organizer
  Proceedings of the Japanese Society for Immunology
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24592841
[Presentation] Induction of nitric oxide by macrophages stimulated with IL-27 and lipopolysaccharide through STAT1, NF-kappaB and MAPKs2012
- Author(s)
  Shimizu M, Mizoguchi I, Mizuguchi J, Yoshimoto T
- Organizer
  Proceedings of the Japanese Society for Immunology
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24592841
[Presentation] BCR刺激によって誘導されるアポトーシスの解析2011
- Author(s)
  秦喜久美、水口純一郎
- Organizer
  第20回日本Cell death学会
- Place of Presentation
  東京大学薬学部(東京)
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PROJECT-21592564
[Presentation] IL-27の抗腫瘍作用におけるマイクロファージの役割2010
- Author(s)
  清水本武, 佐藤真友美, 小倉潔, 武田康隆, 水口純一郎, 善本隆之
- Organizer
  69回日本癌学会学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21592564
[Presentation] インターフェロンαを介するアポトーシス誘導におけるプロティンキナーゼC(PKCs)の役割2010
- Author(s)
  矢那瀬紀子, 水口純一郎
- Organizer
  第19回日本Cell Death学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21592564
[Presentation] Requirement for arginine methylation in FOXO3a-mediated G1 arrest of WEHI-231 B lymphoma cells upon engagement of B cell antigen receptor for antigen2010
- Author(s)
  Mizuguchi J, Kikumi H
- Organizer
  18th Euroconference on apoptosis
- Place of Presentation
  Ghent, Belgium
- Data Source
  KAKENHI-PROJECT-21592564
[Presentation] Requirement for Arginine Methylation in FOXO3a-mediated G1 Arrest of WEHI-231 B Lymphoma Cells upon Engagement of B Cell Receptor for Antigen2010
- Author(s)
  Mizuguchi J, Hata K
- Organizer
  18th Euroconference on Apoptosis
- Place of Presentation
  Ghent, Belgium
- Data Source
  KAKENHI-PROJECT-21592564
[Presentation] 口腔扁平上皮癌患者由来の原発巣及び転移巣における遺伝子発現解析2009
- Author(s)
  秦喜久美、水口純一郎, 他
- Organizer
  第164回東京医科大学医学総会
- Place of Presentation
  東京医科大学病院
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-21592564
[Presentation] ASK-JNK signaling pathway mediates apoptosis through reactive oxygen species following engagement of membrane immunoglobulin in WEHI-231 B lymphoma cells2009
- Author(s)
  Mizuguchi J, Takada E, Hata K, Furuhata M
- Organizer
  17th ECDO Euroconference
- Place of Presentation
  Institut Pasteur, Paris, France
- Data Source
  KAKENHI-PROJECT-21592564
[Presentation] IL-27による組織適合抗原の発現上昇と抗腫瘍機構の解析2009
- Author(s)
  清水本武, 佐藤真友美, 小倉潔, 武田康隆, 水口純一郎, 善本隆之
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21592564
[Presentation] Assessment of gene expression involved in development and progression of oral squamous cell carcinoma2008
- Author(s)
  Hata, K, Matsuda, K, Mizuguchi, J
- Organizer
  The 62nd Annual meeting of the Japanese stomatological Society
- Place of Presentation
  Fukuoka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] 口腔扁平上皮癌患者由来の原発巣及び転移巣における遺伝子発現解析2008
- Author(s)
  松田憲一, 千葉博茂, 水口純一郎, 他
- Organizer
  第26回日本口腔腫瘍学会総会
- Place of Presentation
  別府(大分県)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] 口腔扁平上皮癌の発症、進展に及ぼす遺伝子発現解析2008
- Author(s)
  秦喜久美, 松田憲一, 水口純一郎
- Organizer
  第62回日本口腔科学会学術集会
- Place of Presentation
  福岡(福岡県)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] 口腔扁平上皮癌の発症・進展に及ぼす遺伝子発現解析2008
- Author(s)
  秦喜久美、松田憲一、水口純一郎
- Organizer
  第62回日本口腔科学会学術集会
- Place of Presentation
  福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] B細胞抗原受容体を介するアポトーシス誘導におけるBimとBaxの役割2007
- Author(s)
  高田栄子, 秦喜久美, 水口純一郎
- Organizer
  第16回日本アポトーシス研究会年会
- Place of Presentation
  東邦大学理学部(千葉県)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] TRAIL介在性及び非介在性のインターフェロンα誘導性アポトーシスの解析2007
- Author(s)
  Yanase N, Kanetaka Y, Toyota H, Mizuguchi J
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  品川(東京都)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] TRAIL介在性及び非介在性のインターフェロンα誘導性アポトーセスの解析2007
- Author(s)
  Yanase N, Kanetaka Y, Toyota H, Mizuguchi J
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  品川(東京都)
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] B細胞抗原受容体を介するアポトーシス誘導におけるBimとBaxの役割2007
- Author(s)
  高田栄子、秦喜久美、水口純一郎
- Organizer
  第16回日本アポトーシス研究会年会
- Place of Presentation
  東邦大学理学部 (千葉県)
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Participation of JNK activation in induction of apoptotic death in normal B cells following engagement of membrane immunoglobulin2006
- Author(s)
  Takada E, Hata K, Sudo K, Mizuguchi J
- Organizer
  第36回日本免疫学会総会
- Place of Presentation
  大阪(大阪府)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] IFN-α stimulates anti-apoptotic pathway at least through NF-kB in B lymphoma cells2006
- Author(s)
  Kanetaka Y, Hoshika A, Yanase N, Mizuguchi J
- Organizer
  第36回日本免疫学会総会
- Place of Presentation
  大阪(大阪府)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Participation of JNK activation in induction of apoptotic death in normal B cells following engagement of membrane immunoglobulin2006
- Author(s)
  Takada, E, Hata, K, Sudo, K, Mizuguchi, J
- Organizer
  The 36th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] IFN-a stimulates anti-apoptotic pathway at least through NF-kB in B lymphoma cells2006
- Author(s)
  Kanetaka, Y, Hoshika, A, Yanase., N, Mizuguchi, J
- Organizer
  The 36th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] PKC-δfunction as proapoptotic molecule in IFN-α-induced apoptosis of Daudi B lymphoma cells2006
- Author(s)
  Yanase N, Hayashida M, Kanetaka Y, Mizuguchi J
- Organizer
  第36回日本免疫学会総会
- Place of Presentation
  大阪(大阪府)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Disruption of trail-receptor-mediate cell death pathway contributes to acquistion of metastatic phenotype of squamous cell carcinoma cells2006
- Author(s)
  Noutomi T, Itoh M, Takada E, Mizuguchi J
- Organizer
  18th congress of the European Association for Cranio-Maxillofacial Surgery
- Place of Presentation
  Spain Barcelona
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] IFN-αによる抗-IgM誘導性アポトーシスの増強2005
- Author(s)
  矢那瀬紀子, 林田美穂, 金高由季, 水口純一郎
- Organizer
  第35回日本免疫学会総会横浜
- Place of Presentation
  横浜(神奈川県)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] 腫瘍細胞選択的プロモーターを用いた切断型Baxによる効率的な細胞死誘導2005
- Author(s)
  豊田博子, 水口純一郎
- Organizer
  第35回日本免疫学会総会横浜
- Place of Presentation
  横浜(神奈川県)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] IFN-α誘導性アポトーシスにおけるPKC deltaの役割2005
- Author(s)
  林田美穂, 矢那瀬紀子, 金高由季, 秦喜久美, 星加明徳, 水口純一郎
- Organizer
  第35回日本免疫学会総会横浜
- Place of Presentation
  横浜(神奈川県)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Role of BH3-only proteins Bim and Bax in B cell antigen receptor-mediated apoptosis2005
- Author(s)
  Takada, E, HATA, K, Mizuguchi, J
- Organizer
  The 35th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] B細胞抗原受容体を介するアポトーシスにおけるBH3単独タンパク質BimおよびBax-αの役割2005
- Author(s)
  高田栄子, 秦喜久美, 水口純一郎
- Organizer
  第35回日本免疫学会総会横浜
- Place of Presentation
  横浜(神奈川県)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Efficient induction of apoptosis by truncated from of Bax driven by tumor-selective promoter2005
- Author(s)
  Toyota, H, Mizuguchi, J
- Organizer
  The 35th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Antigen on nanoparticles enhances anti-tumor immune responses as well as humoral antibody responses
- Author(s)
  Junichiro Mizuguchi, Hiroko Toyota, Noriko Yanase,Takayuki Yoshimoto, Mitsunori Harada, Yasuki Kato
- Organizer
  4th International Conference on Vaccines & Vaccination
- Place of Presentation
  Valencia, Spain
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-26350516
[Presentation] Regulation of anti-tumor immune responses through differentiation and mobilization of hematopoietic stem cells by IL-27
- Author(s)
  Chiba Y, Mizoguchi I, Hisada M, Tsuchida A, Mizuguchi J, and Yoshimoto T.
- Organizer
  第７３回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592841
[Presentation] Nanoparticles function as adjuvant to enhance anti-tumor immune responses as well as humoral antibody responses in vivo.
- Author(s)
  Toyota H, Yanase N, Yoshimoto T, Harada M, and Mizuguchi J.
- Organizer
  第４３回日本免疫学会総会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24592841
[Presentation] Nanoparticles function as adjuvant to enhance anti-tumor immune responses as well as humoral antibody responses in vivo
- Author(s)
  Toyota　Hiroko, Yanase Noriko、Yoshimoto　Takayuki , Harada　Mitsunori, Mizuguchi Junichiro
- Organizer
  第4３回日本免疫学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26350516
[Presentation] ミセル化ナノ粒子によるガンワクチンの開発
- Author(s)
  矢那瀬紀子、豊田博子、秦喜久美、原田充訓、横須賀忠、水口純一郎
- Organizer
  第２６回日本生体防御学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-07-10 – 2015-07-12
- Data Source
  KAKENHI-PROJECT-26350516
[Presentation] BCR刺激誘導性増殖抑制におけるFOXO3aの働き/FOXO3a mediates the G1 arrest through upregulation of B cell translocation gene(Btg) following engagement of membrane immunoglobulin in WEHI-231 B lymphoma cells
- Author(s)
  秦喜久美, 高田栄子, 水口純一郎
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21592564
[Presentation] IL-27 exerts potent antitumor activity by promoting the differentiation of hematopoietic stem cells to M1-like antitumor macrophages and their mobilization
- Author(s)
  Chiba Y, Furusawa J, Mizoguchi I, Xu M, Mizuguchi J, and Yoshimoto T.
- Organizer
  第４３回日本免疫学会総会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24592841
[Presentation] Antigen on nanoparticles enhances anti-tumor immune responses as well as humoral antibody
- Author(s)
  Mizuguchi J, Toyota H, Yanase N, Yoshimoto T, Harada M, and Kato Y.
- Organizer
  4th International Conference on Vaccines & Vaccination
- Place of Presentation
  Valencia, Spain
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-24592841

1. TAKADA Eiko (50110903)

# of Collaborated Projects: 6 results

# of Collaborated Products: 24 results
2. HATA Kikumi (30287156)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
3. CHIBA Hiroshige (80105478)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. YANASE Noriko (10210303)

# of Collaborated Projects: 4 results

# of Collaborated Products: 28 results
5. SATOMI Takashi (70276921)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TOYOTA Hiroko (80468660)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
7. WATANABE Masato (40349460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NAKANISHI Mamoru (90090472)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TORIGOE Chikako (70237163)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. YOSHIMOTO Takayuki (80202406)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. MATSUO Akira (70229417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUZUKI Masako (40385092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ABUKAWA Harutsugi (50453717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HASEGAWA On (50424619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. CHIKAZU Daichi (30343122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FURUHATA Masae (90468661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KATAHIRA Takashi (20626642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TAKEMORI Toshitada (60114295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TOKUHISA Takeshi (20134364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. OHNISHI Kazuo (90169011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KIMOTO Hiroshi (20225080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SUZUKI Kazuo (20192130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ASAKURA Hideki (80142462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. FURUNO Tadahide (80254308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. NANGO Mamoru (90109893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 重本和宏 (00192104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. ISHIMORI Yoshio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. ITOH Hiroyasu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 石森義男

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 伊東博康

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 武田弘資

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 一條秀憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizuguchi Junichiro 水口 純一郎

MIZUGUCHI Junichiro 水口 純一郎

MAZUGUCHI Junichiro 水口 純一郎

Research Projects

Research Products

Co-Researchers

Control of antigen-specific immune response by nanoparticles and elucidation of its cellular mechanism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of inflammation in the initiation and development of oral squamous cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A research for new treatment with parathyroid hormone and cyclooxygenase-2 for mandibular bone invasion by oral squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of cancer stem cells for oral squamous cell carcinoma cells and its application for treatment of oral carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive genome-wide assessment of gene a qn ssion involved in tumor development and metastasis with the goal of clinical application.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic Strategy for Squamous Cell Carcinoma Resistant to Chemotherapeutic AgentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the signal transduction passways through IL-12 receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CISPLATIN-INDUCED APOPTOSIS AGAINST SQUAMOUS CELL CARCINOMA CELLSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study for gene transfection and intracellular distribution of transfected DNA.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Photocontrolled Immune Responses using Photochromic Antigen

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of tyrosine kinase on signal transduction through complement receptor 2 (CD21)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of B cell differentiation and maturation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床免疫44 「B細胞の生存維持とBcl-2ファミリー」2005

Author(s)

Mizuguchi Junichiro 水口純一郎

MIZUGUCHI Junichiro 水口純一郎

MAZUGUCHI Junichiro 水口純一郎