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Takada Eiko  高田 栄子

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TAKADA Eiko  高田 栄子

高田 栄子  タカダ エイコ

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Researcher Number 50110903
Affiliation (Current) 2025: 東京医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2011 – 2015: 東京医科大学, 医学部, 講師
2009: 東京医科大学, 医学部, 講師
2003 – 2007: 東京医科大学, 医学部, 講師
2000 – 2001: 東京医科大学, 医学部, 講師
1993 – 1994: 東京医科大学, 医学部, 講師
Review Section/Research Field
Except Principal Investigator
Pathobiological dentistry/Dental radiology / Surgical dentistry / 病態科学系歯学(含放射線系歯学) / Immunology / General physiology
Keywords
Except Principal Investigator
口腔扁平上皮癌 / TRAIL / apoptosis / squamous cell carcinoma / アポトーシス / 扁平上皮癌 / 薬剤耐性 / JNK / カルボプラチン / CD21 … More / 癌幹細胞 / 転移 / 細胞死 / drug resistance / MAPKs / 薬剤抵抗性 / Microarray / Gene / Tumor / Odontologv / マイクロアレイ / 遺伝子 / 癌 / 歯学 / Bcl-2 family proteins / new treatment modality / chemotherapeutic agents / 併用療法 / Bax-α / 難治性悪性腫瘍 / Bcl2ファミリータンパク質 / 化学療法剤抵抗性 / Bcl-2ファミリータンパク質 / 新規治療法 / 化学療法剤 / Drug-Resistance / Caspase-3 / Bcl-xL / Caboplatin / カスペース3 / Bcl-x_L / signal transduction / phosphorylation / B cell / チロシンキナーゼ / ヒトB細胞 / 補体受容体2 / シグナル伝達 / リン酸化 / B細胞 / 炎症 / 国際情報交換 / PRMT1 / T細胞依存性抗体産生 / タンパク質修飾 / 抗体産生 / アルギニンメチル化 / 治療戦略 Less
  • Research Projects

    (9 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (16 People)
  •  The role of PRMT1 signal on immune response and immune related disease

    • Principal Investigator
      HATA KIKUMI
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Tokyo Medical University
  •  Role of inflammation in the initiation and development of oral squamous cell carcinoma

    • Principal Investigator
      MIZUGUCHI Junichiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical University
  •  口腔扁平上皮癌の化学療法剤耐性及び転移能獲得における細胞死関連分子の役割

    • Principal Investigator
      納冨 武則
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical University
  •  Characterization of cancer stem cells for oral squamous cell carcinoma cells and its application for treatment of oral carcinoma

    • Principal Investigator
      MIZUGUCHI Junichiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tokyo Medical University
  •  Comprehensive genome-wide assessment of gene a qn ssion involved in tumor development and metastasis with the goal of clinical application.

    • Principal Investigator
      MIZUGUCHI Junitiro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tokyo Medical University
  •  Elucidation of molecular mechanisms for chemoresistance and development of new treatment modalities.

    • Principal Investigator
      ITO Mizue
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical University
  •  Therapeutic Strategy for Squamous Cell Carcinoma Resistant to Chemotherapeutic Agents

    • Principal Investigator
      MIZUGUCHI Junichiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical University
  •  CISPLATIN-INDUCED APOPTOSIS AGAINST SQUAMOUS CELL CARCINOMA CELLS

    • Principal Investigator
      MAZUGUCHI Junichiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Tokyo Medical University
  •  Role of tyrosine kinase on signal transduction through complement receptor 2 (CD21)

    • Principal Investigator
      MIZUGUCHI Junichiro
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Tokyo Medical College

All 2013 2010 2009 2007 2006 2005 2003 Other

All Journal Article Presentation Book

  • [Book] 臨床免疫44 「B細胞の生存維持とBcl-2ファミリー」2005

    • Author(s)
      高田 栄子, 水口 純一郎
    • Publisher
      科学評論社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] Requirement of apoptosis-inducing kinase 1 for the induction of bronchial asthma following stimulation with ovalbumin.2013

    • Author(s)
      Takada, E., Furuhata, M., Nakae, S., Ichijo, H., Sudo, K. and Mizuguchi, J.
    • Journal Title

      Int. Arch. Allergy Immunol.

      Volume: 162 Issue: 2 Pages: 104-114

    • DOI

      10.1159/000353240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-24592841, KAKENHI-PROJECT-25650061
  • [Journal Article] Enhanced T cell-independent antibody responses in c-Jun N-terminal kinase 2(JNK2)-deficient B cells following stimulation with CpG-1826 and anti-IgM2010

    • Author(s)
      Cao Y, Takada E, Hata K, Sudo K, Furuhata M, Mizuguchi J
    • Journal Title

      Immunol Lett

      Volume: 132 Pages: 38-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592564
  • [Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand induces apoptotic cell death through c-Jun NH2-teriminal kinase activation in squamous cell carcinoma cells2009

    • Author(s)
      Noutomi T, Itoh M, Toyota H, Takada E, and Mizuguchi J
    • Journal Title

      Oncol Rep

      Volume: 22 Pages: 1169-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592564
  • [Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand induces apoptoric cell death through c-Jun NH2-terminal kinase activation in squamous cell carcinoma cells.2009

    • Author(s)
      Noutomi T, Itoh M, Toyota H, Takada E., Mizuguchi J.
    • Journal Title

      Oncol Rep 22(5)

      Pages: 1169-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592564
  • [Journal Article] Apoptosis signal-regulating kinase(ASK)-1 mediates apoptosis through activation of JNK1 following engagement of membrane immunoglobulin.2009

    • Author(s)
      Furuhata M, Takada E, Noguchi T, Ichijo H, Mizuguchi J
    • Journal Title

      Exp Cell Res

      Volume: 315 Pages: 3467-3476

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592564
  • [Journal Article] Apoptosis signal-regulating kinase(ASK)-1 mediates apoptosis through activation of JNK1 following enagement of membrane immunoglobulin.2009

    • Author(s)
      Furuhata M, Takada E, Noguchi T, Ichijo H.., Mizuguchi J.
    • Journal Title

      Exp Cell Res 10;315(20)

      Pages: 3467-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592564
  • [Journal Article] c-Jun-NH(2)-terminal kinase potentiates apoptotic cell death in response to carboplatin in Blymphoma cells2007

    • Author(s)
      Takada E, Hata K, Mizuguchi J
    • Journal Title

      Cancer Chemother Pharmacol (Epub ahead of print)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] c-Jun-NH2-terminal kinase potentiates apoptotic cell death in response to carboplatin in B lymphoma cells2007

    • Author(s)
      Takada, E, Hata, K, Mizuguchi, J
    • Journal Title

      Cancer Chemother Pharmacol

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] c-Jun-NH(2)-terminal kinase potentiates apoptotic cell death in response to carboplatin in B lymphoma cells2007

    • Author(s)
      Takada E, Hata K, Mizuguchi J
    • Journal Title

      Cancer Chemother Pharmacol (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] Requirement for JNK-dependent upregulation of BimL in anti-IgM-induced apoptosis in murine B lymphoma cell lines WEHI-231 and CH31.2006

    • Author(s)
      Takada, Hata, Mizuguchi.
    • Journal Title

      Experimental Cell Research 312(19)

      Pages: 3728-3738

    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] Requirement for JNK-dependent upregulation of BimL in anti-IgM-induced apoptosis in murine B lymphoma cell lines WEHI.231 and CH312006

    • Author(s)
      Takada, E, Hata, J, Mizueuchi, J
    • Journal Title

      Exp Cell Res 312-19

      Pages: 3728-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] Requirement for JNK-dependent upregulation of BimL in anti-IgM-induced apoptosis in murine B lymphoma cell lines WEHI-231 and CH312006

    • Author(s)
      Takada E, Hata K, Mizuguchi J.
    • Journal Title

      Exp Cell Res 312(19)

      Pages: 3728-38

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells2005

    • Author(s)
      Takada E, Shimo K, Hata K, Abiake M, Mukai Y, Moriyama M, Heasley L, Mizuguchi J
    • Journal Title

      Exp Cell Res 304(2)

      Pages: 518-30

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] Interferon-beta-induced activation of c-Jun NH2- terminal kinase mediates apoptosis through upregulation of CD95 in CH31 B lymphoma cells2005

    • Author(s)
      Takada, E, Shimo, K, Hata, K, Abiake, M, Mukai, Y, Moriyama, M, Heasley, L, Mizuguchi, J
    • Journal Title

      Exp Cell Res 304-2

      Pages: 518-530

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through upregulation of CD95 in CH31 B lymphoma cells.2005

    • Author(s)
      Takada, Shimo, Hata, Aiake, Mukai, Moriyama, Heasley, Mizuguchi.
    • Journal Title

      Experimental Cell Research 304(2)

      Pages: 518-530

    • Data Source
      KAKENHI-PROJECT-17390545
  • [Journal Article] Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis-factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential.2003

    • Author(s)
      Hotta T, Suzuki H, Nagai S, Yamamoto T, Imakiire A, Takada E, Itoh M, Mizuguchi J.
    • Journal Title

      J Orthop Res. 21

      Pages: 949-957

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15592003
  • [Presentation] ASK-JNK signaling pathway mediates apoptosis through reactive oxygen species following engagement of membrane immunoglobulin in WEHI-231 B lymphoma cells2009

    • Author(s)
      Mizuguchi J, Takada E, Hata K, Furuhata M
    • Organizer
      17th ECDO Euroconference
    • Place of Presentation
      Institut Pasteur, Paris, France
    • Data Source
      KAKENHI-PROJECT-21592564
  • [Presentation] B細胞抗原受容体を介するアポトーシス誘導におけるBimとBaxの役割2007

    • Author(s)
      高田 栄子、秦喜 久美、水口 純一郎
    • Organizer
      第16回日本アポトーシス研究会年会
    • Place of Presentation
      東邦大学理学部 (千葉県)
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Presentation] B細胞抗原受容体を介するアポトーシス誘導におけるBimとBaxの役割2007

    • Author(s)
      高田 栄子, 秦喜 久美, 水口 純一郎
    • Organizer
      第16回日本アポトーシス研究会年会
    • Place of Presentation
      東邦大学理学部(千葉県)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Presentation] Role of Bim and Bax in the induction of apoptosis following engagement on membrane immunoglobulin2007

    • Author(s)
      Takada, E, Hata, K, Mizueuchi, J
    • Organizer
      The 16th annual meeting on apoptosis
    • Place of Presentation
      Chiba
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Presentation] Participation of JNK activation in induction of apoptotic death in normal B cells following engagement of membrane immunoglobulin2006

    • Author(s)
      Takada E, Hata K, Sudo K, Mizuguchi J
    • Organizer
      第36回日本免疫学会総会
    • Place of Presentation
      大阪(大阪府)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Presentation] Disruption of TRAIL Receptor- Mediated Cell Death Pathway Contributes to Acquisition of Metastatic Phenotype of Squamous Cell Carcinoma Cells2006

    • Author(s)
      Noutomi, T, Itoh, M, Takada, E, Mizueuchi, J
    • Organizer
      18th Congress of the European Association for Cranio-Maxillofacial Surgery
    • Place of Presentation
      Spain Barcelona
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Presentation] Disruption of trail-receptor-mediate cell death pathway contributes to acquistion of metastatic phenotype of squamous cell carcinoma cells2006

    • Author(s)
      Noutomi T, Itoh M, Takada E, Mizuguchi J
    • Organizer
      18th congress of the European Association for Cranio-Maxillofacial Surgery
    • Place of Presentation
      Spain Barcelona
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Presentation] Participation of JNK activation in induction of apoptotic death in normal B cells following engagement of membrane immunoglobulin2006

    • Author(s)
      Takada, E, Hata, K, Sudo, K, Mizuguchi, J
    • Organizer
      The 36th Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Presentation] B細胞抗原受容体を介するアポトーシスにおけるBH3単独タンパク質BimおよびBax-αの役割2005

    • Author(s)
      高田 栄子, 秦 喜久美, 水口 純一郎
    • Organizer
      第35回日本免疫学会総会 横浜
    • Place of Presentation
      横浜(神奈川県)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Presentation] Role of BH3-only proteins Bim and Bax in B cell antigen receptor-mediated apoptosis2005

    • Author(s)
      Takada, E, HATA, K, Mizuguchi, J
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390545
  • [Presentation] BCR刺激誘導性増殖抑制におけるFOXO3aの働き/FOXO3a mediates the G1 arrest through upregulation of B cell translocation gene(Btg) following engagement of membrane immunoglobulin in WEHI-231 B lymphoma cells

    • Author(s)
      秦喜久美, 高田栄子, 水口純一郎
    • Organizer
      第39回日本免疫学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21592564
  • 1.  MIZUGUCHI Junichiro (20150188)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 24 results
  • 2.  HATA Kikumi (30287156)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 21 results
  • 3.  CHIBA Hiroshige (80105478)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  TOYOTA Hiroko (80468660)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  YANASE Noriko (10210303)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  SATOMI Takashi (70276921)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MATSUO Akira (70229417)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  WATANABE Masato (40349460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  FURUHATA Masae (90468661)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KATAHIRA Takashi (20626642)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ASAKURA Hideki (80142462)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  YOSHIMOTO Takayuki (80202406)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ITO Mizue (00398760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  納冨 武則 (40459590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  武田 弘資
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  一條 秀憲
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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