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ABEI Masato  安部井 誠人

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… Alternative Names

阿部井 誠人  アベイ マサト

ABEO Masato  安部井 誠人

安倍井 誠人  アベイ マサト

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Researcher Number 20261802
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2011 – 2015: 筑波大学, 医学医療系, 准教授
2010: 筑波大学, 大学院・人間総合科学研究科, 准教授
2008: 筑波大学, 大学院・人間総合科学研究科, 講師
2006: 筑波大学, 大学院人間総合科学研究科, 講師
2004 – 2006: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Assistant Professor, 大学院・人間総合科学研究科, 講師
1994 – 2003: Institute of Clinical Medicine, Assistant Professor, 臨床医学系, 講師
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology
Except Principal Investigator
Gastroenterology / Cerebral neurosurgery / Applied pharmacology / Cerebral neurosurgery
Keywords
Principal Investigator
アデノウイルス / 遺伝子治療 / コレステロール / 胆石 / adenovirus / gene therapy / gallbladder cancer / 胆嚢癌 / lecithin / n-3 polyunsaturated fatty acids … More / fish oil / eicosapentaenoic acid / gallstone / cholesterol / リン脂質 / 魚油 / エイコサペンタエン酸 / 胆道癌 / 腫瘍融解ウイルス / integrin / bile duct cancer / biliary cancer / コクサッキー・アデノウイルス受容体 / インテグリン / 胆管癌 / mucin / phospholipids / W-3多価不飽和脂肪酸 / レシチン / w-3多価不飽和脂肪酸 / ソラフェニブ / ワクシニアウイルス / 癌幹細胞 / 肝細胞癌 / 遺伝子化学療法 / UPRT / 5-fluorouracil / サイクロフォスファマイド / カルシウム結合蛋白 / 炭酸カルシウム / カルシウム … More
Except Principal Investigator
VEGF / metronomic chemotherapy / Juzen Taiho To / CPT-11 / hypoxia inducible factor / angiogenesis / glioma / グリオーマ / 血管新生 / soluble VEGF receptor / angiopietin / 分子標的治療 / 可溶性VEGFレセプター / 十全大補湯 / soluble Flt-1 / vascular endothelial growth factor / adenovirus / gene therapy / gallbladder cancer / ウラシルホスホリボシルトランスフェラーゼ / 胆管癌 / 胆道癌 / ウラシルフォスフォリボシルトランスフェラーゼ / 5-フルオロウラシル / 胆嚢癌 / アデノウイルス / 遺伝子治療 / crystal growth / immunoglobulins / biliary protein / nucleation / alpha_1-acid glycoprotein / cholesterol / gallstone / α_1-acid glycoprotein / nucleation time / コレステロール胆石症 / 胆石症 / α_1-アシドグリコプロテイン / 結晶成長 / α_1アシドグリコプロテイン / 免疫グロブリン / 胆汁蛋白 / 結晶析出 / 酸性糖蛋白 / コレステロール / 胆石 / SIRT1 / siRNA / p53 / MDM2 / 胃癌 / 血管内皮増殖因子 / 再生医学 / 遺伝子 / SDF1 / 脳神経疾患 / CXCR7 / CXCR4 / SDF-1 / 低酸素 / 血管新生抑制 / 腫瘍血管内皮細胞 / ケモカイン / 血管内皮前駆細胞 / 脳腫瘍学 Less
  • Research Projects

    (12 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (22 People)
  •  Evaluation of cytotoxic effects of oncolytic vaccinia virus on cancer stem cells of liver cancers.Principal Investigator

    • Principal Investigator
      Abei Masato
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells

    • Principal Investigator
      HYODO Ichinosuke
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      University of Tsukuba
  •  Evaluation of efficacy and safety of gene-chemotherapy for biliary cancers using oncolytic adenovirus armed with UPRTPrincipal Investigator

    • Principal Investigator
      ABEI Masato
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  Antiangiogenic therapy using endothelial progenitor cells for malignant tumors

    • Principal Investigator
      TAKANO Shingo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      University of Tsukuba
  •  Experimental Efficacy of Fiber-modified Cancer-selectively Replicating Adenovirus for Gene Therapy of Biliary CancersPrincipal Investigator

    • Principal Investigator
      ABEI Masato
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  Experimental Analysis and Application of Cancer-selectively Replicating Adenovirus for Gene Therapy of Gallbladder Cancer.

    • Principal Investigator
      TANAKA Naomi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  Anti-angiogenic therapy for malignant gliomas using hypoxia-responsive soluble VEGF receptor

    • Principal Investigator
      TAKANO Shingo
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      University of Tsukuba
  •  Experimental Efficacy of Adenovirus-mediated Gene Therapy for Gallbladder CancerPrincipal Investigator

    • Principal Investigator
      ABEI Masato
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  Animal study and clinical efficacy of fish oil (eicosapentaenoic acid) on dissolution of cholesterol gallstones.Principal Investigator

    • Principal Investigator
      ABEI Masato
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  Experimental analysis of inhibitory effect of n-3 polyunsaturated fatty acid on cholesterol gallstone.Principal Investigator

    • Principal Investigator
      ABEI Masato
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  コレステロール胆石の石灰化の成因:胆汁中炭酸カルシウム飽和度と析出抑制活性の解析Principal Investigator

    • Principal Investigator
      阿部井 誠人
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  Role of cholesterol crystallization-promoting protein in the pathogenesis of cholesterol gallstone.

    • Principal Investigator
      TANAKA Naomi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba

All 2015 2014 2013 2012 2011 2010 2004

All Journal Article Presentation

  • [Journal Article] Identification of a unique hepatocellular carcinoma line, Li-7, with CD13(+) cancer stem cells hierarchy and population change upon its differentiation during culture and effects of sorafenib.2015

    • Author(s)
      Takeshi Yamada, Masato Abei, Inaho Danjoh, Ryoko Shiota, Taro Yamashuita, Ichinosuke Hyodo, Yukio Nakamura.
    • Journal Title

      BMC Cancer

      Volume: 15 Issue: 1 Pages: 260-260

    • DOI

      10.1186/s12885-015-1297-7

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460975
  • [Journal Article] Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters2013

    • Author(s)
      Hasegawa N, Abei M, Yokoyama KK, Fukuda K, Seo E, Kawashima R, Nakano Y, Yamada T, Nakade K, Hamada H, Obata Y, Hyodo I
    • Journal Title

      Int. J.Cancer

      Volume: PMID: 23444104(印刷中) Issue: 6 Pages: 1479-1488

    • DOI

      10.1002/ijc.28132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590755, KAKENHI-PROJECT-23501277
  • [Journal Article] EpCAM- and EGFR- targeted selective gene therapy for biliary cancers using Z33-fiber modified adenovirus2011

    • Author(s)
      Kawashima R, Abei M, Fukuda K, Nakamura K, Murata T, Wakayama M, Seo E, Hasegawa N, Mizuguchi H, Obata Y, Hyodo I, Hamada H, Yokoyama KK
    • Journal Title

      Int. J. Cancer

      Volume: 129巻 Pages: 1244-1253

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Journal Article] Potent in vitroand in vivo anti-tumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells2011

    • Author(s)
      Endo S, Yamato K, Hirai S, MoriwakiT, Fukuda K, Suzuki H, Abei M, Nakagawa I, Hyodo I.
    • Journal Title

      Cancer Sci

      Volume: 102(3) Pages: 605-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590497
  • [Journal Article] 腫瘍選択的増殖型アデノウイルスを用いた胆道癌の遺伝子治療の研究とその展望2004

    • Author(s)
      安部井誠人, 他
    • Journal Title

      医学と薬学 52

      Pages: 885-893

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370174
  • [Journal Article] 腫瘍選択的増殖型アデノウイルスを用いた胆道癌の遺伝子治療の研究とその展望2004

    • Author(s)
      安部井誠人, 他
    • Journal Title

      医学と薬学 52

      Pages: 885-893

    • Data Source
      KAKENHI-PROJECT-16390203
  • [Journal Article] Researches and future perspectives on gene therapy for biliary cancers using tumor-selectively replicating adenoviruses.2004

    • Author(s)
      Masato Abei, et al.
    • Journal Title

      Igaku to yakuri 52(6)

      Pages: 885-893

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390203
  • [Journal Article] Researches and future perspectives on gene therapy for biliary cancers using tumor-selectively replicating adenoviruses2004

    • Author(s)
      Masato Abei, et al.
    • Journal Title

      Igaku to yakuri 52(6)

      Pages: 885-893

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390203
  • [Presentation] Identification of A Hepatocellular Carcinoma Cell Line, Li-7, Capable of Monitoring The Differentiation of CD13(+)CD166(-) Cancer Stem Cells And Effects of Sorafenib.2015

    • Author(s)
      Takeshi Yamada, Masato Abei M, Inaho Danjoh, Ichinosuke Hyodo, Yukio Nakamura.
    • Organizer
      米国癌学会(AACR)2015
    • Place of Presentation
      米国フィラデルフィア,ペンシルバニアコンベンションセンター
    • Year and Date
      2015-04-20
    • Data Source
      KAKENHI-PROJECT-25460975
  • [Presentation] Identification of A Hepatocellular Carcinoma Cell Line, Ki-7, Capable of Monitoring the Differentiation of CD13(+)CD166(-) Cancer Stem Cells and Effects of Sorafenib.2015

    • Author(s)
      Takeshi Yamada, Masato Abei, Inaho Danjoh, Ryoko Shiota, Taro Yamashita, Ichinosuke Hyodo, Yukio Nakamura.
    • Organizer
      米国癌学会(AACR)2015
    • Place of Presentation
      米国フィラデルフィア,ペンシルバニアコンベンションセンター
    • Year and Date
      2015-04-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460975
  • [Presentation] A hepatocellular carcinoma (HCC) line able to monitor cancer stem cells differentiation and the effects of drugs targeting CSC.2014

    • Author(s)
      Takeshi Yamada, Masato Abei M, Inaho Danjoh, Ichinosuke Hyodo, Yukio Nakamura.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-25460975
  • [Presentation] UPRT遺伝子武装腫瘍融解アデノウイルスを用いた膵癌の遺伝子化学療法の基礎的検討 (2): シクロフォスファミドによる免疫抑制との併用効果2013

    • Author(s)
      長谷川直之,安部井誠人,福田邦明,兵頭一之介
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      かごしま県民交流センター,鹿児島
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] UPRT遺伝子武装腫瘍融解アデノウイルスを用いた膵癌の遺伝子化学療法の基礎的検討 (1):免疫適格同種ハムスター膵癌モデルにおける有効性と安全性の評価2013

    • Author(s)
      長谷川直之,安部井誠人,福田邦明,兵頭一之介
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      かごしま県民交流センター,鹿児島
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] Introduction to oncolytic virus therapy as novel cancer therapeutics2012

    • Author(s)
      Abei M
    • Organizer
      第4回 West Japan Oncology Group International Symposium on Clinical Trial
    • Place of Presentation
      福岡ヒルトンホテル,福岡
    • Year and Date
      2012-04-07
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] Efficacy and safety of oncolytic adenovirus combined with UPRT/5-FU suicide gene system: Evaluation in syngenic pancreas cancer model in immunocompetent,adenovirus-permissive Syrian hamsters.2012

    • Author(s)
      Hasegawa N, Abei M, Fukuda K,Kawashima R,Seo E, WakayamaM, Hamada H, Yokoyama KK, Obata Y, Hyodo I
    • Organizer
      第18回日本遺伝子治療学会総会
    • Place of Presentation
      熊本テルサ,熊本
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] 胆管細胞癌に対する標的化遺伝子治療と陽子線治療の研究. ワークショップ15 胆管細胞癌の現状と展開2012

    • Author(s)
      安部井誠人,福田邦明,奥村敏之
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      ホテル日航金沢,金沢
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] Efficacy and safety of gene-chemo therapy using oncolytic adenovirus expressing uracil phosphoribosyl transferase (UPRT) followed by 5-fluorouracil administration in syngenic pancreatic and biliary cancers in immunocompetent adenoviruspermissive Syrian ha2012

    • Author(s)
      Hasegawa N, Abei M, Fukuda K,SeoE, Wakayama M, KawashimaR, Murata T, Hamada H, YokoyamaKK, Obata Y, Hyodo I.
    • Organizer
      第15回米国遺伝子・細胞治療学会
    • Place of Presentation
      ペンシルベニア・コンベンションセンター,フィラデルフィア,アメリカ合衆国
    • Year and Date
      2012-05-17
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] Targeted and armed oncolytic vaccinia virus JX-594 for treating advanced liver cancers: Recent advances in global clinical trials and our clinical trial plan in Japan.2012

    • Author(s)
      Abei, M, Hyodo I, Kirn DH
    • Organizer
      第18回日本遺伝子治療学会総会
    • Place of Presentation
      熊本テルサ,熊本
    • Year and Date
      2012-06-30
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] Immunosuppression enhances the Efficacy of oncolytic adenovirus-mediated uracil phosphoribosyl Transferase (UPRT)/ 5-fluorouracil suicide gene therapy in immunocompetent adenoviruspermissive Syrian hamsters2012

    • Author(s)
      Hasegawa N, Abei M, Fukuda K,Seo E,Wakayama M, Kawashima R, Hamada H, Yokoyama KK, Obata Y, Hyodo I
    • Organizer
      2012国際癌遺伝子・細胞治療学会(ISCGT)
    • Place of Presentation
      フラマホテル,シンガポール
    • Year and Date
      2012-10-04
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] EpCAM- and EGFR-targeted selective gene therapy for biliarycancers using Z33-fiber-modified adenovirus.2010

    • Author(s)
      安部井誠人
    • Organizer
      第16回日本遺伝子治療学会
    • Place of Presentation
      宇都宮栃木県総會文化センター
    • Year and Date
      2010-07-02
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] 癌遺伝子治療研究の最近の動向:腫瘍融解ウイルス療法の概念,現状と将来展望. 特別講演2010

    • Author(s)
      安部井誠人
    • Organizer
      第28回日本ヒト細胞学会
    • Place of Presentation
      研究交流センター,つくば
    • Year and Date
      2010-08-30
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] EpCAM and EGFR-targeted selective gene therapy for biliary cancers using Z33-fiber modified adenovirus.2010

    • Author(s)
      Abei M, Kawashima R, Fukuda K, Nakamura K, Murata T,Yokoyama KK,Hamada H, Hyodo I
    • Organizer
      第16回日本遺伝子治療学会総会
    • Place of Presentation
      栃木県総合文化センター,宇都宮
    • Year and Date
      2010-07-02
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] 癌遺伝子治療研究の最近の動向:腫瘍融解ウイルス療法の概念,現状と将来展望2010

    • Author(s)
      安部井誠人
    • Organizer
      第28回日本ヒト細胞学会
    • Place of Presentation
      つくば文部科学省研究交流センター
    • Year and Date
      2010-08-22
    • Data Source
      KAKENHI-PROJECT-22590755
  • 1.  YOKOYAMA Kazunari (80182707)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  HYODO Ichinosuke (60416469)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 3.  TODOROKI Takeshi (70114105)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  TAKANO Shingo (50292553)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  HAMADA Hirofumi (00189614)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  TANAKA Naomi (60111530)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OHNEDA Osamu (30311872)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YAMASHITA Toshiharu (50400677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  EMA Masatsugu (60359578)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IMAGAWA Shigehiko (60231164)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SHIMIZU Takashi (00338782)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SUZUKI Hideo (00400672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  FUKUDA Kuniaki (50447257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 14.  NAGATA KYOSUKE (40180492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  YAMASHITA TATSUROU (90377432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SONE Hirohito (30312846)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TSUBOI Koji (90188615)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  植田 琢也 (40361448)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  中村 幸夫 (60231479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 20.  MITSUI Yoji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  三ツ井 洋司
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YAMASHITA Taro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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