ABEI Masato 安部井誠人

… Alternative Names

Researcher Number	20261802
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011 – 2015: 筑波大学, 医学医療系, 准教授 2010: 筑波大学, 大学院・人間総合科学研究科, 准教授 2008: 筑波大学, 大学院・人間総合科学研究科, 講師 2006: 筑波大学, 大学院人間総合科学研究科, 講師 2004 – 2006: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Assistant Professor, 大学院・人間総合科学研究科, 講師 1994 – 2003: Institute of Clinical Medicine, Assistant Professor, 臨床医学系, 講師
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Cerebral neurosurgery / Applied pharmacology / Cerebral neurosurgery
Keywords	Principal Investigator 胆石 / コレステロール / 遺伝子治療 / アデノウイルス / 腫瘍融解ウイルス / 胆道癌 / エイコサペンタエン酸 / 魚油 / リン脂質 / cholesterol … More Except Principal Investigator 血管新生 / グリオーマ / glioma / angiogenesis / hypoxia inducible factor / CPT-11 / Juzen Taiho To / metronomic chemotherapy / VEGF / 脳腫瘍学 / 血管内皮前駆細胞 / ケモカイン / 腫瘍血管内皮細胞 / 血管新生抑制 / 低酸素 / SDF-1 / CXCR4 / CXCR7 / 脳神経疾患 / SDF1 / 遺伝子 / 再生医学 / 血管内皮増殖因子 / 胃癌 / MDM2 / p53 / siRNA / SIRT1 / 胆石 / コレステロール / 酸性糖蛋白 / 結晶析出 / 胆汁蛋白 / 免疫グロブリン / α_1アシドグリコプロテイン / 結晶成長 / α_1-アシドグリコプロテイン / 胆石症 / コレステロール胆石症 / nucleation time / α_1-acid glycoprotein / gallstone / cholesterol / alpha_1-acid glycoprotein / nucleation / biliary protein / immunoglobulins / crystal growth / 遺伝子治療 / アデノウイルス / 胆嚢癌 / 5-フルオロウラシル / ウラシルフォスフォリボシルトランスフェラーゼ / 胆道癌 / 胆管癌 / ウラシルホスホリボシルトランスフェラーゼ / gallbladder cancer / gene therapy / adenovirus / vascular endothelial growth factor / soluble Flt-1 / 十全大補湯 / 可溶性VEGFレセプター / 分子標的治療 / angiopietin / soluble VEGF receptor Less

Evaluation of cytotoxic effects of oncolytic vaccinia virus on cancer stem cells of liver cancers.Principal Investigator
- Principal Investigator
  
  Abei Masato
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells
- Principal Investigator
  
  HYODO Ichinosuke
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Tsukuba
Evaluation of efficacy and safety of gene-chemotherapy for biliary cancers using oncolytic adenovirus armed with UPRTPrincipal Investigator
- Principal Investigator
  
  ABEI Masato
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
Antiangiogenic therapy using endothelial progenitor cells for malignant tumors
- Principal Investigator
  
  TAKANO Shingo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tsukuba
Experimental Efficacy of Fiber-modified Cancer-selectively Replicating Adenovirus for Gene Therapy of Biliary CancersPrincipal Investigator
- Principal Investigator
  
  ABEI Masato
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
Experimental Analysis and Application of Cancer-selectively Replicating Adenovirus for Gene Therapy of Gallbladder Cancer.
- Principal Investigator
  
  TANAKA Naomi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
Anti-angiogenic therapy for malignant gliomas using hypoxia-responsive soluble VEGF receptor
- Principal Investigator
  
  TAKANO Shingo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tsukuba
Experimental Efficacy of Adenovirus-mediated Gene Therapy for Gallbladder CancerPrincipal Investigator
- Principal Investigator
  
  ABEI Masato
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
Animal study and clinical efficacy of fish oil (eicosapentaenoic acid) on dissolution of cholesterol gallstones.Principal Investigator
- Principal Investigator
  
  ABEI Masato
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
Experimental analysis of inhibitory effect of n-3 polyunsaturated fatty acid on cholesterol gallstone.Principal Investigator
- Principal Investigator
  
  ABEI Masato
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
コレステロール胆石の石灰化の成因:胆汁中炭酸カルシウム飽和度と析出抑制活性の解析Principal Investigator
- Principal Investigator
  
  阿部井誠人
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
Role of cholesterol crystallization-promoting protein in the pathogenesis of cholesterol gallstone.
- Principal Investigator
  
  TANAKA Naomi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba

All 2015 2014 2013 2012 2011 2010 2004

All Journal Article Presentation

[Journal Article] Identification of a unique hepatocellular carcinoma line, Li-7, with CD13(+) cancer stem cells hierarchy and population change upon its differentiation during culture and effects of sorafenib.2015
- Author(s)
  Takeshi Yamada, Masato Abei, Inaho Danjoh, Ryoko Shiota, Taro Yamashuita, Ichinosuke Hyodo, Yukio Nakamura.
- Journal Title
  
  BMC Cancer
  
  Volume: 15 Pages: 260-260
- DOI
  10.1186/s12885-015-1297-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460975
[Journal Article] Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters.2013
- Author(s)
  Hasegawa N, Abei M, Yokoyama KK, Fukuda K, Seo E, Kawashima R, Nakano Y, Yamada T, Nakade K, Hamada H, Obata Y, Hyodo I
- Journal Title
  
  Int J Cancer
  
  Volume: PMID: 23444104(印刷中) Pages: 1479-1488
- DOI
  10.1002/ijc.28132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590755, KAKENHI-PROJECT-23501277
[Journal Article] EpCAM- and EGFR- targeted selective gene therapy for biliary cancers using Z33-fiber modified adenovirus2011
- Author(s)
  Kawashima R, Abei M, Fukuda K, Nakamura K, Murata T, Wakayama M, Seo E, Hasegawa N, Mizuguchi H, Obata Y, Hyodo I, Hamada H, Yokoyama KK
- Journal Title
  
  Int. J. Cancer
  
  Volume: 129巻 Pages: 1244-1253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590755
[Journal Article] Potent in vitroand in vivo anti-tumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells2011
- Author(s)
  Endo S, Yamato K, Hirai S, MoriwakiT, Fukuda K, Suzuki H, Abei M, Nakagawa I, Hyodo I.
- Journal Title
  
  Cancer Sci
  
  Volume: 102(3) Pages: 605-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590497
[Journal Article] 腫瘍選択的増殖型アデノウイルスを用いた胆道癌の遺伝子治療の研究とその展望2004
- Author(s)
  安部井誠人, 他
- Journal Title
  
  医学と薬学 52
  
  Pages: 885-893
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370174
[Journal Article] 腫瘍選択的増殖型アデノウイルスを用いた胆道癌の遺伝子治療の研究とその展望2004
- Author(s)
  安部井誠人, 他
- Journal Title
  
  医学と薬学 52
  
  Pages: 885-893
- Data Source
  KAKENHI-PROJECT-16390203
[Journal Article] Researches and future perspectives on gene therapy for biliary cancers using tumor-selectively replicating adenoviruses.2004
- Author(s)
  Masato Abei, et al.
- Journal Title
  
  Igaku to yakuri 52(6)
  
  Pages: 885-893
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390203
[Journal Article] Researches and future perspectives on gene therapy for biliary cancers using tumor-selectively replicating adenoviruses2004
- Author(s)
  Masato Abei, et al.
- Journal Title
  
  Igaku to yakuri 52(6)
  
  Pages: 885-893
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390203
[Presentation] Identification of A Hepatocellular Carcinoma Cell Line, Li-7, Capable of Monitoring The Differentiation of CD13(+)CD166(-) Cancer Stem Cells And Effects of Sorafenib.2015
- Author(s)
  Takeshi Yamada, Masato Abei M, Inaho Danjoh, Ichinosuke Hyodo, Yukio Nakamura.
- Organizer
  米国癌学会(AACR)2015
- Place of Presentation
  米国フィラデルフィア，ペンシルバニアコンベンションセンター
- Year and Date
  2015-04-20
- Data Source
  KAKENHI-PROJECT-25460975
[Presentation] Identification of A Hepatocellular Carcinoma Cell Line, Ki-7, Capable of Monitoring the Differentiation of CD13(+)CD166(-) Cancer Stem Cells and Effects of Sorafenib.2015
- Author(s)
  Takeshi Yamada, Masato Abei, Inaho Danjoh, Ryoko Shiota, Taro Yamashita, Ichinosuke Hyodo, Yukio Nakamura.
- Organizer
  米国癌学会(AACR)2015
- Place of Presentation
  米国フィラデルフィア，ペンシルバニアコンベンションセンター
- Year and Date
  2015-04-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460975
[Presentation] A hepatocellular carcinoma (HCC) line able to monitor cancer stem cells differentiation and the effects of drugs targeting CSC.2014
- Author(s)
  Takeshi Yamada, Masato Abei M, Inaho Danjoh, Ichinosuke Hyodo, Yukio Nakamura.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-25460975
[Presentation] UPRT遺伝子武装腫瘍融解アデノウイルスを用いた膵癌の遺伝子化学療法の基礎的検討 (2): シクロフォスファミドによる免疫抑制との併用効果2013
- Author(s)
  長谷川直之,安部井誠人,福田邦明,兵頭一之介
- Organizer
  第99回日本消化器病学会総会
- Place of Presentation
  かごしま県民交流センター,鹿児島
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] UPRT遺伝子武装腫瘍融解アデノウイルスを用いた膵癌の遺伝子化学療法の基礎的検討 (1):免疫適格同種ハムスター膵癌モデルにおける有効性と安全性の評価2013
- Author(s)
  長谷川直之,安部井誠人,福田邦明,兵頭一之介
- Organizer
  第99回日本消化器病学会総会
- Place of Presentation
  かごしま県民交流センター,鹿児島
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] Introduction to oncolytic virus therapy as novel cancer therapeutics2012
- Author(s)
  Abei M
- Organizer
  第4回 West Japan Oncology Group International Symposium on Clinical Trial
- Place of Presentation
  福岡ヒルトンホテル,福岡
- Year and Date
  2012-04-07
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] Efficacy and safety of oncolytic adenovirus combined with UPRT/5-FU suicide gene system: Evaluation in syngenic pancreas cancer model in immunocompetent,adenovirus-permissive Syrian hamsters.2012
- Author(s)
  Hasegawa N, Abei M, Fukuda K,Kawashima R,Seo E, WakayamaM, Hamada H, Yokoyama KK, Obata Y, Hyodo I
- Organizer
  第18回日本遺伝子治療学会総会
- Place of Presentation
  熊本テルサ,熊本
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] 胆管細胞癌に対する標的化遺伝子治療と陽子線治療の研究. ワークショップ15 胆管細胞癌の現状と展開2012
- Author(s)
  安部井誠人,福田邦明,奥村敏之
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  ホテル日航金沢,金沢
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] Efficacy and safety of gene-chemo therapy using oncolytic adenovirus expressing uracil phosphoribosyl transferase (UPRT) followed by 5-fluorouracil administration in syngenic pancreatic and biliary cancers in immunocompetent adenoviruspermissive Syrian ha2012
- Author(s)
  Hasegawa N, Abei M, Fukuda K,SeoE, Wakayama M, KawashimaR, Murata T, Hamada H, YokoyamaKK, Obata Y, Hyodo I.
- Organizer
  第15回米国遺伝子・細胞治療学会
- Place of Presentation
  ペンシルベニア・コンベンションセンター,フィラデルフィア,アメリカ合衆国
- Year and Date
  2012-05-17
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] Targeted and armed oncolytic vaccinia virus JX-594 for treating advanced liver cancers: Recent advances in global clinical trials and our clinical trial plan in Japan.2012
- Author(s)
  Abei, M, Hyodo I, Kirn DH
- Organizer
  第18回日本遺伝子治療学会総会
- Place of Presentation
  熊本テルサ,熊本
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] Immunosuppression enhances the Efficacy of oncolytic adenovirus-mediated uracil phosphoribosyl Transferase (UPRT)/ 5-fluorouracil suicide gene therapy in immunocompetent adenoviruspermissive Syrian hamsters2012
- Author(s)
  Hasegawa N, Abei M, Fukuda K,Seo E,Wakayama M, Kawashima R, Hamada H, Yokoyama KK, Obata Y, Hyodo I
- Organizer
  2012国際癌遺伝子・細胞治療学会(ISCGT)
- Place of Presentation
  フラマホテル,シンガポール
- Year and Date
  2012-10-04
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] EpCAM- and EGFR-targeted selective gene therapy for biliarycancers using Z33-fiber-modified adenovirus.2010
- Author(s)
  安部井誠人
- Organizer
  第16回日本遺伝子治療学会
- Place of Presentation
  宇都宮栃木県総會文化センター
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] 癌遺伝子治療研究の最近の動向:腫瘍融解ウイルス療法の概念,現状と将来展望. 特別講演2010
- Author(s)
  安部井誠人
- Organizer
  第28回日本ヒト細胞学会
- Place of Presentation
  研究交流センター,つくば
- Year and Date
  2010-08-30
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] EpCAM and EGFR-targeted selective gene therapy for biliary cancers using Z33-fiber modified adenovirus.2010
- Author(s)
  Abei M, Kawashima R, Fukuda K, Nakamura K, Murata T,Yokoyama KK,Hamada H, Hyodo I
- Organizer
  第16回日本遺伝子治療学会総会
- Place of Presentation
  栃木県総合文化センター,宇都宮
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-22590755
[Presentation] 癌遺伝子治療研究の最近の動向:腫瘍融解ウイルス療法の概念,現状と将来展望2010
- Author(s)
  安部井誠人
- Organizer
  第28回日本ヒト細胞学会
- Place of Presentation
  つくば文部科学省研究交流センター
- Year and Date
  2010-08-22
- Data Source
  KAKENHI-PROJECT-22590755

1. YOKOYAMA Kazunari (80182707)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. HYODO Ichinosuke (60416469)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
3. TODOROKI Takeshi (70114105)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TAKANO Shingo (50292553)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HAMADA Hirofumi (00189614)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. TANAKA Naomi (60111530)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OHNEDA Osamu (30311872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAMASHITA Toshiharu (50400677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. EMA Masatsugu (60359578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IMAGAWA Shigehiko (60231164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHIMIZU Takashi (00338782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUZUKI Hideo (00400672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. FUKUDA Kuniaki (50447257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
14. NAGATA KYOSUKE (40180492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YAMASHITA TATSUROU (90377432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SONE Hirohito (30312846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TSUBOI Koji (90188615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 植田琢也 (40361448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 中村幸夫 (60231479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. MITSUI Yoji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 三ツ井洋司

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAMASHITA Taro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 中出浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ABEI Masato 安部井 誠人

阿部井 誠人 アベイ マサト

ABEO Masato 安部井 誠人

安倍井 誠人 アベイ マサト

Research Projects

Research Products

Co-Researchers

Evaluation of cytotoxic effects of oncolytic vaccinia virus on cancer stem cells of liver cancers.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of efficacy and safety of gene-chemotherapy for biliary cancers using oncolytic adenovirus armed with UPRTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Antiangiogenic therapy using endothelial progenitor cells for malignant tumors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental Efficacy of Fiber-modified Cancer-selectively Replicating Adenovirus for Gene Therapy of Biliary CancersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental Analysis and Application of Cancer-selectively Replicating Adenovirus for Gene Therapy of Gallbladder Cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anti-angiogenic therapy for malignant gliomas using hypoxia-responsive soluble VEGF receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental Efficacy of Adenovirus-mediated Gene Therapy for Gallbladder CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Animal study and clinical efficacy of fish oil (eicosapentaenoic acid) on dissolution of cholesterol gallstones.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental analysis of inhibitory effect of n-3 polyunsaturated fatty acid on cholesterol gallstone.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

コレステロール胆石の石灰化の成因:胆汁中炭酸カルシウム飽和度と析出抑制活性の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of cholesterol crystallization-promoting protein in the pathogenesis of cholesterol gallstone.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Identification of a unique hepatocellular carcinoma line, Li-7, with CD13(+) cancer stem cells hierarchy and population change upon its differentiation during culture and effects of sorafenib.2015

ABEI Masato 安部井誠人

阿部井誠人アベイマサト

ABEO Masato 安部井誠人

安倍井誠人アベイマサト