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KAKIHANA Yasuyuki  垣花 泰之

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Researcher Number 20264426
Other IDs
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Affiliation (Current) 2022: 鹿児島大学, 医歯学域医学系, 教授
Affiliation (based on the past Project Information) *help 2015 – 2022: 鹿児島大学, 医歯学域医学系, 教授
2015: 鹿児島大学, 医歯学域 医学部・歯学部附属病院 集中治療部, 教授
2013: 鹿児島大学, 医歯学総合研究科, 教授
2011 – 2013: 鹿児島大学, 医歯(薬)学総合研究科, 教授
2011 – 2012: 鹿児島大学, 大学院・医歯学総合研究科, 教授 … More
2011: 鹿児島大学, 医歯学総合研究科, 教授
2009 – 2010: Kagoshima University, 医学部・歯学部附属病院, 講師
2003 – 2006: Kagoshima University, University Hospital, Faculty of Medicine and Dentistry, Assistant, 医学部・歯学部附属病院, 講師
2001 – 2002: Kagoshima University, University Hospital, Faculty of Medicine, Assistant Professor, 医学部附属病院, 講師
2000: 鹿児島大学, 医学部・附属病院, 講師
1999: 鹿児島大学, 医学部・附属病院, 助手
1998: 鹿児島大学, 医学部附属病院, 助手
1998: University Hospital Kagoshima University, Research Associate, 医学附属病院, 助手
1997: Kagoshima University University Hospital, Reseach Associate, 医学部・附属病院, 助手
1995: 鹿児島大学, 医学部・附属病院, 助手
1994: Kagoshima University School of Medicine Assistant Professor, 医学部・付属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Emergency medicine / Basic Section 55060:Emergency medicine-related
Except Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology / Emergency medicine / Basic Section 55060:Emergency medicine-related / Anesthesiology/Resuscitation studies / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords
Principal Investigator
近赤外線分光法 / 近赤外分光法 / チトクロームオキシダーゼ / cytochrome oxidase / Near-infrared spectroscopy / チトクロムオキシダーゼ / 低酸素症 / 肝酸素化状態 / 時間分解分光法 / 酸素化型ヘモグロビン … More / NIRS / 超低体温下完全循環停止 / deep hypothermic circulatory arrest / S-100β蛋白 / 脳障害 / 体外循環 / mild hypothermic therapy / 脳内酸素飽和度 / 心肺蘇生法 / ヘモグロビン / 脳虚血 / 脳塞栓症 / 周術期管理学 / 近赤外時間分解分光システム / 脳障害モニタリング / ヘモグロビン酸素飽和度 / 光路長 / 時間分解分光システム / 腹部急性疾患 / 腸管虚血 / 非侵襲的モニタリング / 脱酸素化型ヘモグロビン / 肝臓 / 腸管 / 虚血 / 肝虚血 / 肝静脈血酸素飽和度 / 肝血流量 / エンドトキシン / OXy-Hb / deoxy-Hb / Cytochrome oxidase / Hepatic oxygenation / Shvo_2 / lacate / portal flow / Near-Infrared spectroscopy / oxygenated hemoglobin / hepatic oxygenation / hepatic ischemia / hepatic venous saturation / hepatic blood flow / endotoxin / 対外循環 / 脳酸素化状態モニタリング / チトクロームオキシターゼ / 超低体温 / 完全循環停止 / 脳酸素化状態 / S-100b蛋白 / 内頸静脈酸素飽和度 / チトフロームオキシターゼ / S-100蛋白 / Cardiopulmonary bypass / cerebral oxygenation / 内頚静脈血酸素飽和度 / 脳保護療法 / 軽度脳低体温療法 / 低体温療法 / 時間分解計測法 / jugular venous oxygen saturation / s-100β protein / cerebral protection therapy / 脳分離循環 / 脳低体温療法 / 集中治療 / 脳高次機能障害 / cardiopulmonary bypass / cerebral injury / separate cerebral perfusion / s-100βprotein / intensive care unit / 近赤外線時間分解分光法 / 蘇生後脳症 / 心停止 / チトクロームaa3 / 散乱係数 / 脳浮腫 / TRS / cardiopulmonary arrest / encephalopathy / scattering coefficient / cerebral SO2 / MRI / 心肺蘇生 / ROSC / 脳モニタリング / 救命 / モニタリング / 脳・神経 / 自己心拍再開 / 胸骨圧迫 / 空間分解分光法 / 胸骨圧迫法 / 心肺停止 / 脳酸素飽和度 / 順行性脳血流 … More
Except Principal Investigator
近赤外分光法 / 近赤外線分光法 / 心筋酸素代謝 / Myocardial oxygen metabolism / HMGB1 / トロンボモジュリン / 組織損傷 / DAMPs / 敗血症 / 肝動脈血流量 / 門脈血流量 / 肝酸素化状態 / エンドトキシン / 肝うっ血 / 肝灌流モデル / ガスセンサ / 揮発性有機化合物(VOCs) / 患者評価 / VOCs / 呼気ガス分析 / 半導体式ガスセンサ / 接触燃焼式ガスセンサ / 周術期管理 / 呼気ガスバイオマーカー / 虚血 / 酸素化 / 肝臓 / ショック / 肝虚血 / 経食道的分析 / Near-infrared spectrophotometry / Transesophageal analysis / 体酸素代謝 / 心収縮力 / 左室圧-容積関係(LVPVR) / 収縮期末圧-容積関係(ESPVR) / 収縮期末エラスタンス(Ees) / 体組織酸素代謝 / 左室左-容積関係 / 心筋収縮性 / 低酸素症 / Systemic oxygen metabolism / Myocardial contractility / Left ventricular pressure-volume relations (LVPVR) / End-systomic pressure-volume relations (ESPVR) / End-systolic elastance / S-100β蛋白 / 内頚静脈酸素飽和度 / 体外循環 / 術後脳障害 / チトクロームオキシダーゼ / モノアミン / 脳高次機能障害 / S-100b蛋白 / 内頚静脈血酸素飽和度 / Near-infrared spectroscopy / S-100β protein / SjvO2 / Cardiopulmonary bypass / post-operative brain injury / cytochrome oxidase / 抗凝固薬 / ヘパリン / ヘパリン起因性血小板減少症 / HIT / 血栓症 / ポイントオブケア / ヘパリン起因性血小板減少症(HIT) / 血栓 / 集中治療 / 虚血再灌流障害 / ヒストン / 細胞外ヒストン / 麻酔 / 虚血再灌流傷害 / 虚血再灌流 / DAMPs / PAMPs / RAMPs / 生体損傷 / DIC / プロテインC / 止血 / 修復 / Thrombin / Thrombomodulin / TM / Protein C / EPCR / RAMPs / thrombin / protein C / PAMPs / 核内タンパク質 / アイソフォーム / 抗体 / 播種性血管内凝固(DIC) / 治療 / 診断 / メディエーター / 腸内細菌叢 / メタボローム / 腸内細菌 / 壊死性腸炎 / 新生児外科疾患 / テトラヒドロビオプテリン / 芳香族モノアミン Less
  • Research Projects

    (21 results)
  • Research Products

    (51 results)
  • Co-Researchers

    (36 People)
  •  テトラヒドロビオプテリン・サプライにより新生児壊死性腸炎の中枢機能予後を取戻す

    • Principal Investigator
      杉田 光士郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kagoshima University
  •  腸内細菌叢制御による敗血症の代謝プロファイル再建戦略

    • Principal Investigator
      伊藤 隆史
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Kumamoto University
  •  Development of physiological monitoring method by NIRS to evaluate appropriate chest compression at cardiac arrestPrincipal Investigator

    • Principal Investigator
      垣花 泰之
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Kagoshima University
  •  A novel therapeutic strategy targeting HMGB1 isoforms in sepsis

    • Principal Investigator
      ITO Takashi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Kagoshima University
  •  Novel therapeutic proposal for DIC/Shock: from Damage-Sensing/-Control to Damage Resolution

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Novel simulation technique for diagnosing heparin-induced thrombocytopenia (HIT)

    • Principal Investigator
      Ito Takashi
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Development of cerebral monitoring by the redox state of cytochrome aa3 for post-resuscitation encephalopathyPrincipal Investigator

    • Principal Investigator
      Kakihana Yasuyuki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  evaluation of organ protective effects of anesthetic agents using extra-cellular histone modification in liver ischemia-reperfusion injury

    • Principal Investigator
      Nakahara Mayumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Anesthesiology
    • Research Institution
      Kagoshima University
  •  noninvasive detection of hepatic ischemia by TRS

    • Principal Investigator
      YASUDA TOMOTSUGU
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Kagoshima University
  •  Usefulness of volatile biomarkers in breath for perioperative management

    • Principal Investigator
      MATSUNAGA Akira
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  Development of the new measurement method using the time resolved spectroscopy for the acute abdominal diseasePrincipal Investigator

    • Principal Investigator
      KAKIHANA Yasuyuki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Development of perioperative cerebral monitoring system using near-infrared time-resolved spectroscopyPrincipal Investigator

    • Principal Investigator
      KAKIHANA Yasuyuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  Neuroprotective effects of therapeutic mild hypothermia on postoperative brain injury after cardiopulmonary bypass in intensive care unitsPrincipal Investigator

    • Principal Investigator
      KAKIHANA Yasuyuki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  Monitoring of cognitive dysfunction during cardiopulmonary bypass and establishment of ideal cerebral management

    • Principal Investigator
      KANMURA Yuichi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  Evaluation of new ceerbral protection for postoperative brain injury after cardiopulmonary bypass using near-infrared spectroscopyPrincipal Investigator

    • Principal Investigator
      KAKIHANA Yasuyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima Universit
  •  Monitoring of brain oxygen status using near-infrared spectroscopyPrincipal Investigator

    • Principal Investigator
      KAKIHANA Yasuyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  生理的肝潅流モデルを用いた肝酸素代謝の検討

    • Principal Investigator
      ODA Toshiyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  Experimental approach for clinical use of NIRS as a monitor of hepatic oxygenationPrincipal Investigator

    • Principal Investigator
      KAKIHANA Yasuyuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  Assessment of myocardial oxygen metabolism and its performance during progressive hypoxemia.

    • Principal Investigator
      ODA Toshiyuki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  近赤外分光法および微小循環システムを用いた脳蘇生法の検討Principal Investigator

    • Principal Investigator
      垣花 泰之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  Study on noninvasive and continuaous monitoring of myocardial oxygen metabolism by NIRS

    • Principal Investigator
      ODA Toshiyuki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University

All 2021 2020 2019 2018 2017 2016 2013 2012 2011 2010 2009 2007 2006 2005 2003

All Journal Article Presentation Book

  • [Book] 麻酔・手術後の患者管理2016

    • Author(s)
      伊藤隆史・垣花泰之
    • Total Pages
      360
    • Publisher
      克誠堂出版
    • Data Source
      KAKENHI-PROJECT-16K15764
  • [Book] 大量出血、出血性ショックに対する薬物医療2006

    • Author(s)
      垣花泰之
    • Publisher
      真興交易(株)医書出版部
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Circulating Syndecan-1 as a Predictor of Persistent Thrombocytopenia and Lethal Outcome: A population Study of Patients With Suspected Sepsis Requiring Intensive Care2021

    • Author(s)
      Hatanaka Kosaku、Ito Takashi、Madokoro Yutaro、Kamikokuryo Chinatsu、Niiyama Shuhei、Yamada Shingo、Maruyama Ikuro、Kakihana Yasuyuki
    • Journal Title

      Front Cardiovasc Med.

      Volume: 8 Pages: 730553-730553

    • DOI

      10.3389/fcvm.2021.730553

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03033, KAKENHI-PROJECT-20K09291
  • [Journal Article] Leukocyte-derived extracellular DNA contributes to abnormal pressure elevation in the extracorporeal circulation circuit2020

    • Author(s)
      Yashima Nozomi、Ito Takashi、Kajiyama Kenji、Maeda Hiroyuki、Kakihana Yasuyuki、Maruyama Ikuro
    • Journal Title

      Scientific Reports

      Volume: 10

    • DOI

      10.1038/s41598-019-57173-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-18K19587
  • [Journal Article] Recombinant thrombomodulin alleviates oxidative stress without compromising host resistance to infection in rats infected with methicillin-resistant Staphylococcus aureus2020

    • Author(s)
      Ito Takashi、Shrestha Binita、Kakihana Yasuyuki、Maruyama Ikuro
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 17413-17413

    • DOI

      10.1038/s41598-020-74529-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02904
  • [Journal Article] Circulating histone H3 levels in septic patients are associated with coagulopathy, multiple organ failure, and death: a single-center observational study.2019

    • Author(s)
      Yokoyama Yayoi、Ito Takashi、Yasuda Tomotsugu、Furubeppu Hiroaki、Kamikokuryo Chinatsu、Yamada Shingo、Maruyama Ikuro、Kakihana Yasuyuki
    • Journal Title

      Thromb J.

      Volume: 17 Pages: 1-1

    • DOI

      10.1186/s12959-018-0190-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02904, KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] Fulminant myocarditis associated with severe fever with thrombocytopenia syndrome: a case report2019

    • Author(s)
      Miyamoto S, Ito T, Terada S, Eguchi T, Furubeppu H, Kawamura H, Yasuda T, Kakihana Y.
    • Journal Title

      BMC Infectious Diseases

      Volume: 19 Pages: 266-266

    • DOI

      10.1186/s12879-019-3904-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09236, KAKENHI-PROJECT-18H02904
  • [Journal Article] Serum histone H3 levels and platelet counts are potential markers for coagulopathy with high risk of death in septic patients: a single-center observational study.2019

    • Author(s)
      Ito Takashi、Totoki Takaaki、Yokoyama Yayoi、Yasuda Tomotsugu、Furubeppu Hiroaki、Yamada Shingo、Maruyama Ikuro、Kakihana Yasuyuki
    • Journal Title

      J Intensive Care.

      Volume: 7 Pages: 63-63

    • DOI

      10.1186/s40560-019-0420-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-18H02904, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] Circulating histone H3 levels are increased in septic mice in a neutrophil-dependent manner: preclinical evaluation of a novel sandwich ELISA for histone H32018

    • Author(s)
      Ito Takashi、Nakahara Mayumi、Masuda Yoshiki、Ono Sachie、Yamada Shingo、Ishikura Hiroyasu、Imaizumi Hitoshi、Kamikokuryo Chinatsu、Kakihana Yasuyuki、Maruyama Ikuro
    • Journal Title

      Journal of Intensive Care

      Volume: 6 Pages: 79-79

    • DOI

      10.1186/s40560-018-0348-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19587, KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-18H02904
  • [Journal Article] Circulating activated protein C levels are not increased in septic patients treated with recombinant human soluble thrombomodulin2018

    • Author(s)
      Arishima Takuro、Ito Takashi、Yasuda Tomotsugu、Yashima Nozomi、Furubeppu Hiroaki、Kamikokuryo Chinatsu、Futatsuki Takahiro、Madokoro Yutaro、Miyamoto Shotaro、Eguchi Tomohiro、Haraura Hiroyuki、Maruyama Ikuro、Kakihana Yasuyuki
    • Journal Title

      Thrombosis Journal

      Volume: 16 Pages: 24-24

    • DOI

      10.1186/s12959-018-0178-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19587, KAKENHI-PROJECT-17H04363
  • [Journal Article] Monitoring of Brain Oxygenation During and After Cardiopulmonary Resuscitation: A Prospective Porcine Study.2018

    • Author(s)
      Kakihana Y, Kamikokuryo C, Furubeppu H, Madokoro Y, Futatsuki T, Miyamoto S, Haraura H, Hatanaka K, Eguchi T, Saitoh Y, Miura N, Suzuki H, Ueda Y, Yasuda T, Ito T.
    • Journal Title

      Adv Exp Med Biol.

      Volume: 1072 Pages: 83-87

    • DOI

      10.1007/978-3-319-91287-5_14

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05845, KAKENHI-PROJECT-16K11410
  • [Journal Article] Non-invasive Monitoring of Hepatic Oxygenation Using Time-Resolved Spectroscopy2016

    • Author(s)
      Tomotsugu Yasuda, Keiji Yamaguchi, Takahiro Futatsuki, Hiroaki Furubeppu,    Mayumi Nakahara, Tomohiro Eguchi, Shotaro Miyamoto, Yutaro Madokoro, Shinsaku Terada,  Kentaro Nakamura, Hiroki Harada, Taniguchi Junichiro, Kosuke Yanagimoto, Yasuyuki Kakihana
    • Journal Title

      Oxygen Transport to Tissue

      Volume: 876 Pages: 407-412

    • DOI

      10.1007/978-1-4939-3023-4_51

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861235, KAKENHI-PROJECT-25462443
  • [Journal Article] Sepsis-induced myocardial dysfunction: pathophysiology and management2016

    • Author(s)
      Yasuyuki Kakihana, Takashi Ito, Mayumi Nakahara, Keiji Yamaguchi1 and Tomotsugu   Yasuda
    • Journal Title

      Journal of Intensive Care

      Volume: 4:22 Pages: 1-10

    • DOI

      10.1186/s40560-016-0148-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861235, KAKENHI-PROJECT-15H05684
  • [Journal Article] Recombinant Thrombomodulin Protects Mice against Histone-Induced Lethal Thromboembolism2013

    • Author(s)
      Nakahara M, Ito T, Kawahara KI, Yamamoto M, Nagasato T, Shrestha B, Yamada S, Miyauchi T, Higuchi K, Takenaka T, Yasuda T, Matsunaga A, Kakihana Y, Hashiguchi T, Kanmura Y, Maruyama I
    • Journal Title

      PLoS One

      Volume: 30:8 Pages: 75961-75961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659700
  • [Journal Article] Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism2013

    • Author(s)
      Nakahara M, Ito T, et al.
    • Journal Title

      PLoS One.

      Volume: 8(9) Pages: 75961-75961

    • DOI

      10.1371/journal.pone.0075961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12F02424, KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-24659282, KAKENHI-PROJECT-24659700, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25293132, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-25670763, KAKENHI-PROJECT-25670764
  • [Journal Article] Cerebral monitoring using near-infrared time-resolved spectroscopy and postoperative cognitive dysfunction2012

    • Author(s)
      Kakihana Y, Okayama N, Matsunaga A, Yasuda T, Imabayashi T, Nakahara M, Kiyonaga N, Ikoma K, Kikuchi T, Kanmura Y, Oda M, Ohmae E, Suzuki T, Yamashita Y, Tamura M
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 737 Pages: 19-24

    • DOI

      10.1007/978-1-4614-1566-4_3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659700
  • [Journal Article] Effect of pneumoperitoneum on functional residual capacity2012

    • Author(s)
      Matsunaga A, Kakihana Y, et al
    • Journal Title

      Adv Exp Med Biol

      Volume: 737 Pages: 239-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390435
  • [Journal Article] Cerebral monitoring using near-infrared time-resolved spectroscopy and postoperative cognitive dysfunction2012

    • Author(s)
      Kakihana Y, Matsunaga A, Yasuda T, Imabayashi T, Oda M, Yamashita Y, et al
    • Journal Title

      Adv Exp Med Biol

      Volume: 737 Pages: 19-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390435
  • [Journal Article] Effect of pneumoperitoneum on functional residual capacity2012

    • Author(s)
      Matsunaga A, Ohse K, Kakihana Y, Masuda M, Ikoma K, Kanmura Y
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 737 Pages: 239-43

    • DOI

      10.1007/978-1-4614-1566-4_35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659700
  • [Journal Article] Impact of skin incision on the pleth variability index2011

    • Author(s)
      Matsunaga A, Kakihana Y, et al
    • Journal Title

      J Clin Monit Comput

      Volume: 25 Pages: 215-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390435
  • [Journal Article] The effects of the phosphodiesterase inhibitor olprinone on global cerebral ischemia2010

    • Author(s)
      Matsunaga A, Kakihana Y, et al
    • Journal Title

      Anesth Analg

      Volume: 110(3) Pages: 888-894

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390435
  • [Journal Article] 近赤外線分光法による術中の脳酸素化状態モニタリングーチトクロムオキシダーゼ測定はなぜ必要なのか2009

    • Author(s)
      垣花泰之、安田智嗣、今林徹、松永明, 他
    • Journal Title

      脈管学

      Volume: 49 Pages: 147-152

    • NAID

      10025219894

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390435
  • [Journal Article] 心臓血管外科の患者の術前・術中・術後の輸液管理2007

    • Author(s)
      垣花泰之
    • Journal Title

      救急・集中治療 19・1

      Pages: 265-271

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] 人工呼吸管理中の鎮静・鎮痛2007

    • Author(s)
      垣花泰之, 上村裕一
    • Journal Title

      レリニカルエンジニアリング、人工呼吸療法 改訂第4版 1・1

      Pages: 339-345

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] 人工呼吸管理中の鎮静・鎮痛2007

    • Author(s)
      垣花泰之, 上村裕一
    • Journal Title

      クリニカルエンジニアリング、人工呼吸療法 改訂第4版 1・1

      Pages: 339-345

    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] 心臓手術後脳障害に対する脳指向型管理法2007

    • Author(s)
      垣花泰之
    • Journal Title

      日本集中治療医学会雑誌 14・1

      Pages: 27-35

    • NAID

      10020175177

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] 心臓血管外科の患者の術前・術後の輸液管理2007

    • Author(s)
      垣花泰之
    • Journal Title

      救急・集中治療 19・1

      Pages: 265-271

    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Neuroprotective strategies during cardiac surgery involving cardiopulmonary bypass.2007

    • Author(s)
      Kakihana Y
    • Journal Title

      J Jpn Soc Intensive Care Med. 14

      Pages: 27-35

    • NAID

      10020175177

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Clinical effects of a neutrophil elastase inhibitor, sivelestat, in patients with acute respiratory distress syndrome.2006

    • Author(s)
      Okayama N, Kakihana Y, Setoguchi D, Imabayashi T, Omae T, Matsunaga A, Kanmura Y
    • Journal Title

      Journal of Anesthesia 20・1

      Pages: 6-10

    • NAID

      10017245031

    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Clinical effects of a neutrophil elastase inhibitor, sivelestat, in patients with acute respiratory distress syndrome.2006

    • Author(s)
      Okayama N, Kakihana Y, Setoguchi D, Imabayashi T, Omae T, Matsunaga A, Kanmura Y
    • Journal Title

      J Anesth 20

      Pages: 6-10

    • NAID

      10017245031

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Clinical effects of a neutrophil elastase inhibitor, sivelestat, in patients with acute respiratory distress syndrome.2006

    • Author(s)
      Okayama N, Kakihana Y, Setoguchi D, Imabayashi T, Omae T, Matsunaga A, Kanmura Y
    • Journal Title

      J Anesthesia 20・1

      Pages: 6-10

    • NAID

      10017245031

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Hemodynamic changes during off-pump coronary artery bypass anastomosis in patients with coexisting mitral regurgitation : improvement with milrinone2005

    • Author(s)
      Omae T, Kakihana Y, Matsunaga A, Tsuneyoshi I, Kawasaki K, Kanmura Y, Sakata R
    • Journal Title

      Anesth Analg 101・1

      Pages: 2-8

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Effects of olprinone on hepatosplanchnic circulation and mitochondrial oxidation in a porcine model of endotoxemia2005

    • Author(s)
      Kuniyoshi T, Kakihana Y, Isowaki S, Nagata E, Tobo K, Kaminosono T, Hashiguchi T, Tahara M, Kawamae H, Okayama N, Kanmura Y
    • Journal Title

      J Anesth 19・4

      Pages: 295-301

    • NAID

      10016760116

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Hemodynamic changes during off-pump coronary artery bypass anastomosis in patients with coexisting mitral regurgitation : improvement with milrinone2005

    • Author(s)
      Omae T, Kakihana Y, Matsunaga A, Tsuneyoshi I, Kawasaki K, Kanmura Y, Sakata R
    • Journal Title

      Anesth Analg 101

      Pages: 2-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Effects of olprinone on hepatosplanchnic circulation and mitochondrial oxidation in a porcine model of endotoxemia2005

    • Author(s)
      Kuniyoshi T, Kakihana Y, Isowaki S, Nagata E, Tobo K, Kaminosono T, Hashiguchi T, Tahara M, Kawamae H, Okayama N, Kanmura Y
    • Journal Title

      J Anesth 19

      Pages: 295-301

    • NAID

      10016760116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591643
  • [Journal Article] Re-evaluation of the reliability of cytochrome oxidase--signal study of cardiopulmonary bypass2003

    • Author(s)
      Kakihana Y, Kuniyoshi T, Isowaki S, Tobo K, Nagata E, Okayama N, Kitahara K, Moriyama T, Omae T, Kawakami M, Kanmura Y, Tamura M
    • Journal Title

      Adv Exp Med Biol 540

      Pages: 71-75

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370491
  • [Journal Article] Relationship between redox behavior of brain cytochrome oxidase and neurological prognosis2003

    • Author(s)
      Kakihana Y, Kuniyoshi T, Isowaki S, Tobo K, Nagata E, Okayama N, Kitahara K, Moriyama T, Omae T, Kawakami M, Kanmura Y, Tamura M
    • Journal Title

      Adv Exp Med Biol 540

      Pages: 71-75

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370491
  • [Journal Article] Relationship between redox behavior of brain cytochrome oxidase and neurological prognosis2003

    • Author(s)
      Kakihana Y, Kuniyoshi T, Isowaki S, Tobo K, Nagata E, Okayama N, Kitahara K, Moriyama T, Omae T, Kawakami M, Kanmura Y, Tamura M
    • Journal Title

      Adv Exp Med Biol 530

      Pages: 413-419

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370491
  • [Journal Article] Relationship between redox behavior of brain cytochrome oxidase and neurological prognosis2003

    • Author(s)
      Kakihana Y, Kuniyoshi T, Isowaki S, Tobo K, Nagata E, Okayama N, Kitahara K, Moriyama T, Omae T, Kawakami M
    • Journal Title

      Adv Exp Med Biol 530

      Pages: 413-419

    • Data Source
      KAKENHI-PROJECT-14370491
  • [Presentation] 近赤外線分光法の新たな可能性を探るー危機的状況での必須な情報とは?ー2018

    • Author(s)
      垣花泰之
    • Organizer
      第21回日本光脳機能イメージング学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K11410
  • [Presentation] Monitoring of Brain Oxygenation During and After Cardiopulmonary Resuscitation: A Prospective Porcine Study2017

    • Author(s)
      Yasuyuki Kakihana
    • Organizer
      45th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11410
  • [Presentation] 本邦 ICU における HIT 発症頻度の解析ならびに新規検査法の展望2017

    • Author(s)
      伊藤隆史, 上國料千夏, 安田智嗣, 垣花 泰之
    • Organizer
      第44回日本集中治療医学会学術集会
    • Place of Presentation
      ホテルさっぽろ芸文館(北海道札幌市)
    • Data Source
      KAKENHI-PROJECT-16K15764
  • [Presentation] 肺塞栓からショックを引き起こした遅発型ヘパリン起因性血小板減少症(HIT)の一例2017

    • Author(s)
      中弁護, 伊藤隆史, 新門翠, 久保祐輝, 馬場敬太, 政所祐太郎, 宮本昇太郎, 江口智洋, 寺田晋作, 垣花泰之
    • Organizer
      第44回日本集中治療医学会学術集会
    • Place of Presentation
      ロイトン札幌(北海道札幌市)
    • Data Source
      KAKENHI-PROJECT-16K15764
  • [Presentation] 修正大血管転移症に対する三尖弁置換術後に中心静脈圧上昇を伴わない心タンポナー デを認めた一例2016

    • Author(s)
      長嶺嘉通、原田浩輝、岩川昌平、中原真由美、長谷川麻衣子、安田智嗣、垣花泰之、 上村裕一
    • Organizer
      修正大血管転移症に対する三尖弁置換術後に中心静脈圧上昇を伴わない心タンポナー デを認めた一例
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2016-02-12
    • Data Source
      KAKENHI-PROJECT-26861235
  • [Presentation] 敗血症において細胞外ヒストンは主に好中球に由来する2016

    • Author(s)
      中原真由美、伊藤隆史、安田智嗣、垣花泰之、丸山征郎、上村裕一
    • Organizer
      日本麻酔科学会第63回学術集会
    • Place of Presentation
      マリンメッセ福岡(福岡県福岡市)
    • Data Source
      KAKENHI-PROJECT-26861235
  • [Presentation] The successful venoarterial extracorporeal membrane oxygenation tretment in a child with repetitive fulminant myocarditis2016

    • Author(s)
      Y. Madokoro, T. Yasuda, S. Miyamoto, S. Terada, H. Haraura, M. Arima, T. Ito, M. Nakahara, T. Futatsuki, J. Taniguchi, K. Yanagimoto, K. Yamaguchi, Y. Kakihana
    • Organizer
      8th World Congress on Pediatric Intensive and Critical Care
    • Place of Presentation
      Metro Toronto Convention Centre (Toronto, Canada)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861235
  • [Presentation] THE POTENTIAL OF NEAR-INFRARED SPECTROSCOPY AS AN OXYGENATION INDEX OF PIVOTAL ORGANS AND TISSUE OXYGENATION IN CRITICALLY ILL PATIENTS2016

    • Author(s)
      垣花 泰之
    • Organizer
      第8回世界ショック学会
    • Place of Presentation
      東京ドームホテル(東京都文京区)
    • Year and Date
      2016-10-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11410
  • [Presentation] 近赤外線分光法の未知なる可能性を求めてー特に救急・集中治療領域においてー2011

    • Author(s)
      垣花泰之
    • Organizer
      第15回酸素ダイナミクス研究会
    • Place of Presentation
      佐賀
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21390435
  • [Presentation] Dynamic changes in cerebral oxygenation by two methods during cardiac surgery and postoperative cognitive decline2010

    • Author(s)
      Kakihana Y, Yasuda T, Imabayashi T, et al
    • Organizer
      30^<th> International Symposium on Intensive Care and Emergency Medicine
    • Place of Presentation
      Brussels, Belgium
    • Year and Date
      2010-03-08
    • Data Source
      KAKENHI-PROJECT-21390435
  • [Presentation] Cerebral monitoring by Near-infrared time-resolved spectroscopy and postoperative cognitive dysfunction2010

    • Author(s)
      Kakihana Y, Matsunaga A, Oda M, Yamashita Y, et al
    • Organizer
      The 38^<th> Annual Meeting of the International Society on Oxygen Transport to Tissue
    • Place of Presentation
      Ascona, Switzerland
    • Year and Date
      2010-07-19
    • Data Source
      KAKENHI-PROJECT-21390435
  • [Presentation] Cerebral monitoring by near-infrared spectroscopy in the operating room and intensive care unit2009

    • Author(s)
      Kakihana Y.
    • Organizer
      6^<th> International SATO Workshop-Advanced Optical Methods for Assessment and Monitoring of Critical Procedures
    • Place of Presentation
      Erlangen, Germany
    • Year and Date
      2009-06-12
    • Data Source
      KAKENHI-PROJECT-21390435
  • 1.  Ito Takashi (20381171)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 15 results
  • 2.  YASUDA Tomotugu (80437954)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 9 results
  • 3.  MARUYAMA Ikuro (20082282)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 8 results
  • 4.  MATUNAGA Akira (70284883)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 5.  ODA Toshiyuki (90041342)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  上國料 千夏 (50751278)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  IMABAYASHI Toru (90404491)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  SHIMSANOE Kengo (10274531)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TAKAYAMA Chihumi (00265399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  YAMADA Haruhiko (70041481)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KANMURA Yuichi (30211189)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  TOBO Kazumi (30325807)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 13.  Nakahara Mayumi (90707514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 14.  山口 桂司 (50377280)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  川原 幸一 (10381170)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  山口 宗一 (20325814)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  原田 陽一郎 (80464147)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  杉田 光士郎 (50781514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  家入 里志 (00363359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  大西 峻 (10614638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  矢野 圭輔 (30757919)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  新山 修平 (40258455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  政所 祐太郎 (40794061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  加治 建 (50315420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  武藤 充 (70404522)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  一瀬 宏 (90192492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  YAMASHITA Yutaka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 28.  ODA Motoki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 29.  TAMURA Tomomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  HOSOKAWA Kazuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  NAGASATO Tomoka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 32.  田村 知己
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  MIURA Naoki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  YAMADA Shingo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  川村 英樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  橋口 照人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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