Sakai Ryuichi 酒井隆一

… Alternative Names

SAKAI Ryuichi 酒井隆一

酒井隆一サカイリュウイチ

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Researcher Number	20265721
Other IDs	https://orcid.org/0000-0001-6490-0495
External Links
Affiliation (Current)	2024: 北海道大学, 水産科学研究院, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 北海道大学, 水産科学研究院, 教授 2012 – 2016: 北海道大学, 水産科学研究科(研究院), 教授 2014: 北海道大学, 大学院水産科学研究科, 教授 2013: 北海道大学, 大学院水産科学研究院, 教授 2011: 北海道大学, 水産科学研究院, 教授 … More 2010 – 2011: 北海道大学, 大学院・水産科学研究院, 教授 2009 – 2011: 北海道大学, 水産科学研究科, 教授 2009: 北海道大学, 水産学部, 教授 2007: Kitasato University, Fisheries Sciences, Professor 2000 – 2006: 北里大学, 水産学部, 助教授 1996 – 1998: 北里大学, 水産学部, 助教授 1995: 北里大学, 水産食品学科, 助教授 Less
Review Section/Research Field	Principal Investigator Fisheries chemistry / Fisheries chemistry / Basic Section 40040:Aquatic life science-related / Science and Engineering / Aquatic life science / Chemical biology Except Principal Investigator Fisheries chemistry / Chemical biology / Basic Section 38030:Applied biochemistry-related / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related … More / Transformative Research Areas, Section (II) / Medium-sized Section 63:Environmental analyses and evaluation and related fields / Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields / Basic Section 40030:Aquatic bioproduction science-related / Aquatic bioproduction science / Fisheries chemistry / Chemical biology / Living organism molecular science / Neurochemistry/Neuropharmacology / Science and Engineering Less
Keywords	Principal Investigator 海綿 / 海洋天然物 / グルタミン酸受容体 / ポリアミン / ペプチド / レクチン / 生理活性物質 / 興奮性アミノ酸 / ホヤ / ドラッグデリバリー … More / 分子送達 / 膜透過 / ペプチド毒 / アルカロイド / 毒素 / sponge / 生合成 / ダイシハーベイン / 細胞内移行 / タンパク毒素 / エンドサイトーシス / 小胞輸送 / トロンボポエチン受容体 / 生体膜 / ケミカルコミュニケーション / グアニジン / ドラッグデリバリ / トロンボポエチン / グアニジンアルカロイド / タンパク質 / 結晶構造解析 / 生理活性 / dysiherbaine / Dysidea herbacea / 免疫組織化学 / 共生微生物 / シナプス受容体 / 中枢神経 / ベタイン / 神経毒 / ミクロネシア連邦 / 興奮性神経毒 / 海洋天然物化学 / シグナル伝達 / 抗ウイルス / 生態制御物質 / ハリクロナジアミン / プテリン / Cnemidocarpa irene / イソプレノイド / パプアミン / ヨーロッパザラボヤ / マスイメージング / 二次代謝物 / 漁業被害 / メタボロミクス / Cell Penetrating Peptide / 核内移行 / 毒性 / ポリカチオン / ケミカルゲノミクス / 抗真菌 / 摂食阻害 / 海綿食 / タイマイ / 細胞膜 / 生理活性タンパク質 / 海洋生物 / 神経修復 / 細胞内送達 / ビオプテリン / 糖鎖 / サイトカイン / 神経受容体 / 構造決定 / 低分子プローブ / 糖プローブ / 直接構造決定 / X-線構造解析 / biomineralization / peptide / polyamine / natural product chemistry / biological activity / neurotoxin / glutamate receptors / バイオミネラリゼーション / 天然物化学 / glutamate receptor / immunohistochemistry / excitatory amino acid / 局在性 / 組織免疫染色 / Glutamate receptor / kainic acid / red alga / Digenea simplex / マクリ / カイニン酸 / ポリケチド合成酵素 / 非リボゾーム型ペプチド合成酵素 / ジデムニン / symbiosys / biosynthesis / Tistrella mobilis / didemnin / 藍藻 / 適合溶質 / ゲノム / 生合成遺伝子 / イソグアニン / GABA受容体 / 脱感作 / ガレクチン / 海洋生理活性天然物 / Gタンパク質共役型受容体 / プリン / GPCR / 海綿(スポンジ) / アミノ酸 / 抗しゅよう性 / 抗菌性 / 細胞毒性 … More Except Principal Investigator 共生 / Symbiodinium / サンゴ / サンゴ礁生態系 / 褐虫藻 / saxitoxin / ELISA / octocoral / 八放サンゴ / レクチン / シゲミカタトサカ / 天然物 / X線結晶構造解析 / グルタミン酸受容体 / 共生藻 / 麻ひ性貝毒 / コロナウイルス / 抗ウイルス / 抗ウイルス活性 / 糖結合タンパク質 / シナプス受容体モジュレーター / 化学合成 / ミミック / ドラッグデリバリーシステム / ペプチド / ポリアミン / 渦鞭毛藻 / 遺伝子改変 / 化学物質 / ホロビオント / 食物網 / 生態系 / 分布域拡大 / 体組成 / スジアラ / サンゴ礁 / シャコガイ / 共生体 / 生物圏現象 / 海洋生態 / 食物網ルート / シロサケ / サケ / 卵膜軟化症 / stony coral / Symbiosis / Fungia echinata / Theonella sp. / Sinularia lochmodes / シゲミタカトサカ / 六放サンゴ / トゲクサビライシ / Theonella / gonyautoxin / ethanedithiol / thiol / antigen / hapten / paralytic shellfish toxins / マレイミド / ポリクローナル抗体 / 牛血清アルブミン / ポリリジン / 簡易測定法 / 抗体 / 麻ひ性貝毒-チオール複合体 / サキシトキシン / ゴニオトキシン / エタンジチオール / チオール / 抗原 / ハプテン / 麻痺性貝毒 / symbiosis / Sinularia / D-galactose-binding / lectin / Sumbiodinium / 作用標的 / 神経科学 / モジュレーター / 多様性指向型有機合成 / AMPA型受容体 / クリックケミストリー / 人工リガンド / イオンチャネル型グルタミン酸受容体 / 化学プローブ / fragment evolution / リガンド / 生物活性物質 / 天然物有機化学 / 海洋生物資源 / 基質 / アミノ酸 / 神経伝達物質と受容体 / 阻害剤 / トランスポーター / カイニンサン受容体 / 興奮性アミノ酸 / 機能解析 / アンタゴニスト / 構造活性相関 / アンタゴシスト / アゴニスト / サブタイプ / ネオダイシハーベインA / ダイシハーベイン / コッコイド / 運動抑制 / 形態制御 / メタロチオネイン / チオール化合物 / 結合タンパク / ホタテガイ Less

共生体が持つ物質の多様性と生態系における新機能の解明
- Principal Investigator
  
  恒松雄太
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Nagoya University
細胞膜で多彩に機能する有機化合物の合成化学的開発
- Principal Investigator
  
  及川雅人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Yokohama City University
Structure-based functionalization of novel sugar-binding proteins derived from marine natural products for corona drug discovery
- Principal Investigator
  
  田中良和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Tohoku University
Exploring Marine Natural Products that Regulate Dynamic Responses of cellsPrincipal Investigator
- Principal Investigator
  
  酒井隆一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Hokkaido University
サンゴ礁で繁栄する褐虫藻共生システムの体系的理解：学際的研究体制によるアプローチ
- Principal Investigator
  
  山下洋
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields
- Research Institution
  Fisheries Research and Education Agency
体組成変化からアプローチする生物の分布域拡大メカニズム
- Principal Investigator
  
  山下洋
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Fisheries Research and Education Agency
マルチオミクス解析で紐解くホヤのケミカルコミュニケーション戦略Principal Investigator
- Principal Investigator
  
  酒井隆一
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Marine natural products that capture biological brriersPrincipal Investigator
- Principal Investigator
  
  Sakai Ryuichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Hokkaido University
Marine polycations and their roles in chemical communicationPrincipal Investigator
- Principal Investigator
  
  酒井隆一
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Hokkaido University
Potential new food web route for coral reef ecosystems based on zooxanthellae
- Principal Investigator
  
  YAMASHITA Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 40030:Aquatic bioproduction science-related
- Research Institution
  Fisheries Research and Education Agency
Pathogenic mechanism and control of soft egg disease in salmonids
- Principal Investigator
  
  Kasai Hisae
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Aquatic bioproduction science
- Research Institution
  Hokkaido University
A direct structure determination using lectin-carbohydrate complexPrincipal Investigator
- Principal Investigator
  
  Sakai Ryuichi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  Hokkaido University
Search for marine natural products that act on "cellular machinery" on cell surfacePrincipal Investigator
- Principal Investigator
  
  Sakai Ryuichi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Aquatic life science
- Research Institution
  Hokkaido University
Development of selective modulators for synaptic receptors in the central nervous system
- Principal Investigator
  
  Oikawa Masato
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical biology
- Research Institution
  Yokohama City University
Studies toward creation of chemical probes for dissecting structural dynamics of ionotropic glutamate receptors
- Principal Investigator
  
  OIKAWA Masato
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  Yokohama City University
Biosynthtic investigation of the didemninsPrincipal Investigator
- Principal Investigator
  
  SAKAI Ryuichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Fisheries chemistry
- Research Institution
  Hokkaido University
海綿－共生微生物複合体由来の小分子生合成マシナリーの探索Principal Investigator
- Principal Investigator
  
  酒井隆一
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Neuroactive marine metabolites that modulate synaptic functionsPrincipal Investigator
- Principal Investigator
  
  RYUICHI Sakai
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Hokkaido University
Research for useful marineorganisms in Asia and Pacific regions
- Principal Investigator
  
  NAKAO Yoichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Waseda University
Creation of novel bioactive agents on the basis of fragment evolution approach of natural products
- Principal Investigator
  
  OIKAWA Masato
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Yokohama City University
Analysis and generation of functional molecules to modulate neutral amino acid transporters
- Principal Investigator
  
  SHIGERI Yasushi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Sponge-derived neurotoxic substances : Structure, Bioactivity, and their cellular localization.Principal Investigator
- Principal Investigator
  
  SAKAI Ryuichi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kitasato University
グルタミン酸受容体サブタイプ選択的な生体機能分子の創製と機能解析
- Principal Investigator
  
  佐々木誠
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Selection and Morphological Alteration of dinoflagellates symbionts by chemical substances in marine invertebrates
- Principal Investigator
  
  KAMIYA Hisao
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  School of Fisheries Sciences, Kitasato University
Biochemical investigations on the cells that localizes dysiherbaine in marine sponge Dysidea herbacea.Principal Investigator
- Principal Investigator
  
  SAKAI Ryuichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kitasato University
海産無脊椎動物由来の共生藻運動抑制因子
- Principal Investigator
  
  KAMIYA Hisao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kitasato University
CELLULAR LOCALIZATION OF MARINE-DERIVED EXCITATORY AMINO ACIDS IN THEIR PRODUCING ORGANISMSPrincipal Investigator
- Principal Investigator
  
  SAKAI Ryuichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  KITASATO UNIVERSITY
毒化ホタテガイ中腸腺における麻痺性貝毒結合タンパク
- Principal Investigator
  
  SATO Shigeru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kitasato University
Structure and Function of the Octocoral Sinularia lochmodes lectin
- Principal Investigator
  
  KAMIYA Hisao
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  School of Fisheries Sciences, Kitasato University
Development of simple analyzing method for paralytic shellfish toxins by ELISA
- Principal Investigator
  
  SATO Shigeru
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kitasato University
新規興奮性神経毒Dysiherbaineその絶対構造及び構造活性相関についてPrincipal Investigator
- Principal Investigator
  
  酒井隆一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kitasato University
ミクロネシア産海綿のグルタミン酸受容体アゴニスト様物質の構造と単離Principal Investigator
- Principal Investigator
  
  酒井隆一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kitasato University
群体ボヤEcteinascidia turbinata体液中の水溶性生理活性物質Principal Investigator
- Principal Investigator
  
  酒井隆一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kitasato University

[Book] Chemical and Biological Aspects of Water-Soluble Heterocyclic Marine Natural Products. In: Topics in Heterocyclic Chemistry. In Topics in Heterocyclic Chemistry, volume 58, Marine Natural Products2020
- Author(s)
  Ryuichi Sakai
- Total Pages
  517
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19H03040
[Book] Chemical and Biological Aspects of Water-Soluble Heterocyclic Marine Natural Products. In: Topics in Heterocyclic Chemistry. In Topics in Heterocyclic Chemistry, volume 58, Marine Natural Products2020
- Author(s)
  Ryuichi Sakai
- Total Pages
  517
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Book] 天然物の化学II(科学のとびら64): 自然からの贈り物2018
- Author(s)
  酒井隆一　（上村大輔編）
- Total Pages
  192
- Publisher
  東京化学同人
- ISBN
  9784807915057
- Data Source
  KAKENHI-PROJECT-15H04546
[Book] Marine Molecular Biotechnology Marine Toxins as Research Tools(印刷中)
- Author(s)
  Swanson G.T. and Sakai R.
- Publisher
  Springer
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Book] Marine Molecular Biotechnology Marine Toxins as Research Tools
- Author(s)
  Swanson G.T.and Sakai R.
- Publisher
  Springer(印刷中)
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] Interaction of Polyamine-modified Marine Peptide Aculeine A with Cell Membranes: Disruption or Entry2023
- Author(s)
  Watari Hiromi、Kishi Reimi、Matsunaga Satoko、Nishikawa Takayuki、Sawada Yuji、Honda Akito、Fujita Masaki J、Sakai Ryuichi
- Journal Title
  
  Chemistry Letters
  
  Volume: 52 Issue: 3 Pages: 185-189
- DOI
  10.1246/cl.230009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K20589, KAKENHI-PROJECT-23K23695
[Journal Article] Hidden pathway for cytokine receptor activation: a marine sponge-derived lectin reveals sugar-mediated thrombopoietin receptor activation2022
- Author(s)
  Watari Hiromi、Kageyama Hiromu、Masubuchi Nami、Nakajima Hiroya、Onodera Kako、Focia Pamela、Oshiro Takumi、Matsui Takashi、Kodera Yoshio、Ogawa Tomohisa、Yokoyama Takeshi、Hirayama Makoto、Hori Kanji、Freymann Douglas、Komatsu Norio、Araki Marito、Tanaka Yoshikazu、Sakai Ryuichi
- Journal Title
  
  Research Squere
  
  Volume: ―
- DOI
  10.21203/rs.3.rs-1467606/v1
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03040
[Journal Article] A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation2022
- Author(s)
  Watari Hiromi、Kageyama Hiromu、Masubuchi Nami、Nakajima Hiroya、Onodera Kako、Focia Pamela J.、Oshiro Takumi、Matsui Takashi、Kodera Yoshio、Ogawa Tomohisa、Yokoyama Takeshi、Hirayama Makoto、Hori Kanji、Freymann Douglas M.、Imai Misa、Komatsu Norio、Araki Marito、Tanaka Yoshikazu、Sakai Ryuichi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7262-7262
- DOI
  10.1038/s41467-022-34921-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06036, KAKENHI-PROJECT-21K08405, KAKENHI-PROJECT-21K18321, KAKENHI-PROJECT-21K19201, KAKENHI-PROJECT-22K20589, KAKENHI-PROJECT-19KK0178, KAKENHI-PUBLICLY-21H05712, KAKENHI-PROJECT-19H00918, KAKENHI-PROJECT-23K23695
[Journal Article] Menthyl esterification allows chiral resolution for the synthesis of artificial glutamate analogs2021
- Author(s)
  Morokuma Kenji、Tsukamoto Shuntaro、Mori Kyosuke、Miyako Kei、Sakai Ryuichi、Irie Raku、Oikawa Masato
- Journal Title
  
  Beilstein Journal of Organic Chemistry
  
  Volume: 17 Pages: 540-550
- DOI
  10.3762/bjoc.17.48
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04758, KAKENHI-PROJECT-19H03040
[Journal Article] Structure Revision of Protoaculeine B, a Post-translationally Modified N-Terminal Residue in the Peptide Toxin Aculeine B2021
- Author(s)
  Irie Raku、Miyako Kei、Matsunaga Satoko、Sakai Ryuichi、Oikawa Masato
- Journal Title
  
  Journal of Natural Products
  
  Volume: 84 Issue: 4 Pages: 1203-1209
- DOI
  10.1021/acs.jnatprod.0c01280
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04758, KAKENHI-PROJECT-19H03040
[Journal Article] Diverse Aromatic Metabolites in the Solitary Tunicate Cnemidocarpa irene2020
- Author(s)
  Miyako Kei、Yasuno Yoko、Shinada Tetsuro、Fujita Masaki J.、Sakai Ryuichi
- Journal Title
  
  Journal of Natural Products
  
  Volume: 83 Issue: 10 Pages: 3156-3165
- DOI
  10.1021/acs.jnatprod.0c00789
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04758, KAKENHI-PROJECT-19H03040
[Journal Article] Mass spectrometry imaging reveals differential localization of natural sunscreens in the mantle of the giant clam Tridacna crocea2020
- Author(s)
  Goto-Inoue Naoko、Sato Tomohiko、Morisasa Mizuki、Yamashita Hiroshi、Maruyama Tadashi、Ikeda Hiroki、Sakai Ryuichi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 656-656
- DOI
  10.1038/s41598-019-57296-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02270, KAKENHI-PUBLICLY-20H04758
[Journal Article] Total Synthesis of the Proposed Structure for Protoaculeine B, a Polycationic Marine Sponge Metabolite, with a Homogeneous Long-Chain Polyamine2020
- Author(s)
  Irie Raku、Miyahara Masayoshi、Nakamura Shota、Honda Akito、Sakai Ryuichi、Oikawa Masato
- Journal Title
  
  Journal of Natural Products
  
  Volume: 83 Issue: 9 Pages: 2769-2775
- DOI
  10.1021/acs.jnatprod.0c00761
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04758, KAKENHI-PROJECT-19H03040
[Journal Article] Pectenovarin, A New Ovarian Carotenoprotein from Japanese Scallop Mizuhopecten yessoensis2020
- Author(s)
  Matsunaga Satoko、Ikeda Hiroki、Sakai Ryuichi
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 13 Pages: 3042-3042
- DOI
  10.3390/molecules25133042
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Journal Article] Soritesidine, a Novel Proteinous Toxin from the Okinawan Marine Sponge Spongosorites sp.2019
- Author(s)
  Sakai Ryuichi、Tanano Kota、Ono Takumi、Kitano Masaya、Iida Yusuke、Nakano Koji、Jimbo Mitsuru
- Journal Title
  
  Marine Drugs
  
  Volume: 17 Issue: 4 Pages: 216-216
- DOI
  10.3390/md17040216
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04600, KAKENHI-PROJECT-15H04546
[Journal Article] An efficient enantiospecific synthesis of neuroactive glutamate analogues2019
- Author(s)
  Shuntaro Tsukamoto, Hiyori Itagaki, Kenji Morokuma, Kei Miyako, Yuichi Ishikawa, Ryuichi Sakai, Masato Oikawa1
- Journal Title
  
  Heterocycles
  
  Volume: 101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04546
[Journal Article] A novel sponge-derived protein thrombocorticin is a new agonist for thrombopoietin receptor2019
- Author(s)
  Watari Hiromi、Nakajima Hiroya、Atsuumi Wataru、Nakamura Takanori、Nanya Takeshi、Ise Yuji、Sakai Ryuichi
- Journal Title
  
  Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
  
  Volume: 221 Pages: 82-88
- DOI
  10.1016/j.cbpc.2019.04.003
- NAID
  120006864488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04546
[Journal Article] 海綿の長鎖ポリアミン2018
- Author(s)
  酒井隆一、松永智子
- Journal Title
  
  ポリアミン
  
  Volume: 5 Pages: 5-13
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04546
[Journal Article] Prins Reaction Using Trioxane for Trisubstituted, cis-Fused Hexahydro-2H-furo[3,2-b]pyran Derivative2018
- Author(s)
  Oriel Hlokoane, Hiyori Itagaki, Manami Chiba, Taiki Noda, Yuichi Takasaki, Kei Miyako, Ryuichi Sakai, Yuichi Ishikawa,* and Masato Oikawa
- Journal Title
  
  Heterocycles
  
  Volume: 96 Issue: 3 Pages: 453-460
- DOI
  10.3987/com-17-13776
- NAID
  40021512805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04546
[Journal Article] KB343, a Cyclic Tris-guanidine Alkaloid from Palauan Zoantharian Epizoanthus illoricatus2018
- Author(s)
  Ken Matsumura, Tohru Taniguchi, James D. Reimer, Shuntaro Noguchi, Masaki J. Fujita, and Ryuichi Sakai
- Journal Title
  
  Org. Lett.
  
  Volume: 20 Issue: 10 Pages: 3039-3043
- DOI
  10.1021/acs.orglett.8b01069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19221, KAKENHI-PROJECT-15H04546, KAKENHI-PROJECT-15H05629
[Journal Article] Studies on Aculeines: Synthetic Strategy to the Fully Protected Protoaculeine B, the N‐Terminal Amino Acid of Aculeine B2018
- Author(s)
  塩﨑宏樹、宮原正義、大塚一憲、宮古圭、本田彬人、高崎祐一、高見澤聡、塚田秀行、石川裕一、酒井隆一、及川雅人
- Journal Title
  
  Organic Letters
  
  Volume: 20 Issue: 11 Pages: 3403-3407
- DOI
  10.1021/acs.orglett.8b01331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05338, KAKENHI-PROJECT-15H04546
[Journal Article] Crystal structure of octocoral lectin SLL-2 complexed with Forssman antigen tetrasaccharide2017
- Author(s)
  Akiko Kita, Mitsuru Jimbo, Ryuichi Sakai, Yukio Morimoto, Ryota Takeuchi, Hiroshi Tanaka, Takashi Takahashi, Kunio Miki
- Journal Title
  
  Glycobiology
  
  Volume: 27 Issue: 8 Pages: 696-700
- DOI
  10.1093/glycob/cwx043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04546
[Journal Article] Isolation, Amino Acid Sequences, and Plausible Functions of the Galacturonic Acid-Binding Egg Lectin of the Sea Hare Aplysia kurodai2017
- Author(s)
  Motohashi, S., Jimbo, M., Naito, T., Suzuki, T., Sakai, R., Kamiya, H.
- Journal Title
  
  Marine drugs
  
  Volume: 15 Issue: 6 Pages: 161-161
- DOI
  10.3390/md15060161
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04546
[Journal Article] N-Methyl-β-carbolinium Salts and an N-Methylated 8-Oxoisoguanine as Acetylcholinesterase Inhibitors from a Solitary Ascidian, Cnemidocarpa irene2017
- Author(s)
  Yohei Tadokoro, Teruaki Nishikawa, Taichi Ichimori, Satoko Matsunaga, Masaki J Fujita, Ryuichi Sakai
- Journal Title
  
  ACS Omega
  
  Volume: 2 Issue: 3 Pages: 1074-1080
- DOI
  10.1021/acsomega.7b00127
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04546, KAKENHI-PROJECT-15H05629
[Journal Article] Two New Mycosporine-like Amino Acids LC-343 and Mycosporine-ethanolamine from the Micronesian Marine Sponge Lendenfeldia chondrodes2017
- Author(s)
  Oda, Y., Zhang, Q., Matsunaga, S., Fujita, M. J., Sakai, R.
- Journal Title
  
  Chemistry Letters
  
  Volume: 46 Issue: 8 Pages: 1272-1274
- DOI
  10.1246/cl.170490
- NAID
  130005906967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04546
[Journal Article] Three-Component, Diastereoselective Prins-Ritter Reaction for cis-Fused 4-Amidotetrahydropyrans toward a Precursor for Possible Neuronal Receptor Ligands2016
- Author(s)
  Manami Chiba, Yuichi Ishikawa, Ryuichi Sakai, and Masato Oikawa
- Journal Title
  
  ACS combnatorial science
  
  Volume: 18 Issue: 7 Pages: 399-404
- DOI
  10.1021/acscombsci.6b00046
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04546, KAKENHI-PROJECT-26282216
[Journal Article] Mellpaladines and dopargimine, novel neuroactive guanidine alkaloids from a Palauan Didemnidae tunicate2016
- Author(s)
  Hajime Uchimasu, Ken Matsumura, Masashi Tsuda, Keiko Kumagai, Mai Akakabe, Masaki J Fujita, Ryuichi Sakai
- Journal Title
  
  Tetrahedron
  
  Volume: 72 Issue: 45 Pages: 7085-7193
- DOI
  10.1016/j.tet.2016.09.051
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04546
[Journal Article] A monocyclic neodysiherbaine analog: Synthesis and evaluation2016
- Author(s)
  Koichi Fukushima, Yuichi Ishikawa, Ryuichi Sakai, Masato Oikawa
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 21 Issue: 21 Pages: 5164-5167
- DOI
  10.1016/j.bmcl.2016.09.074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04546, KAKENHI-PROJECT-26282216
[Journal Article] Structure–activity relationships of IKM-159: Diverted synthesis and biological evaluation of a series of C5-oxy analogs2015
- Author(s)
  Manami Chiba, Chikako Fujimoto, Ryuichi Sakai, Masato Oikawa
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 25 Issue: 9 Pages: 1869-1871
- DOI
  10.1016/j.bmcl.2015.03.037
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26282216
[Journal Article] Enantioselective synthesis of (+)-N-(desmethyl)dysibetaine CPb2015
- Author(s)
  K. Tanaka, M. Sakai, S. Takamizawa, M. Oikawa
- Journal Title
  
  Chemistry Letters
  
  Volume: 44 Issue: 3 Pages: 253-255
- DOI
  10.1246/cl.141049
- NAID
  130004868376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26282216
[Journal Article] Modulation of ionotropic glutamate receptor function by vertebrate galectins2014
- Author(s)
  Copits, B. A.; Vernon, C. G.; Sakai, R.; Swanson, G. T.
- Journal Title
  
  J. Physiol
  
  Volume: 592 Issue: 10 Pages: 2079-96
- DOI
  10.1113/jphysiol.2013.269597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114
[Journal Article] Recent progress in neuroactive marine natural products2014
- Author(s)
  Sakai, R.; Swanson, G. T.
- Journal Title
  
  Nat. Prod. Rep
  
  Volume: 31 Issue: 2 Pages: 273-309
- DOI
  10.1039/c3np70083f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114
[Journal Article] Practical synthesis of kainoids : a new chemical probe precursor and a fluorescent probe2014
- Author(s)
  Sasaki, S.; Suzuki, H.; Ouchi, H.; Asakawa, T.; Inai, M.; Sakai, R.; Shimamoto, K.; Hamashima, Y.; Kan, T.
- Journal Title
  
  Org Lett
  
  Volume: 16 Issue: 2 Pages: 564-7
- DOI
  10.1021/ol403434e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114, KAKENHI-PROJECT-23390007, KAKENHI-PUBLICLY-24102525, KAKENHI-PROJECT-25620137, KAKENHI-PUBLICLY-26102736, KAKENHI-PROJECT-26860013
[Journal Article] Isolation of novel prototype galectins from the marine ball sponge Cinachyrella sp. guided by their modulatory activity on mammalian glutamate-gated ion channels2013
- Author(s)
  Ueda, T.; Nakamura, Y.; Smith, C. M.; Copits, B. A.; Inoue, A.; Ojima, T.; Matsunaga, S.; Swanson, G. T.; Sakai, R.
- Journal Title
  
  Glycobiology
  
  Volume: 23 Issue: 4 Pages: 412-25
- DOI
  10.1093/glycob/cws165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114, KAKENHI-PUBLICLY-23108503
[Journal Article] “First enantioselective total synthesis of (-)-dysibetaine CPa and absolute configurations of natural product2013
- Author(s)
  6. Michihiro Sakai, Yuichi Ishikawa, Satoshi Takamizawa, Masato Oikawa
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 55 (44) Issue: 44 Pages: 5911-5912
- DOI
  10.1016/j.tetlet.2013.08.113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350028, KAKENHI-PROJECT-25560418
[Journal Article] Studies on an (S)-2-amino-3-(3-hydroxy- 5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159 : asymmetric synthesis, neuroactivity, and structural characterization2013
- Author(s)
  Juknaite, L.; Sugamata, Y.; Tokiwa, K.; Ishikawa, Y.; Takamizawa, S.; Eng, A.; Sakai, R.; Pickering, D. S.; Frydenvang, K.; Swanson, G. T.; Kastrup, J. S.; Oikawa, M.
- Journal Title
  
  J. Med. Chem
  
  Volume: 56 Issue: 6 Pages: 2283-93
- DOI
  10.1021/jm301590z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114, KAKENHI-PROJECT-23350028, KAKENHI-PUBLICLY-23108503
[Journal Article] Structure of a tetrameric galectin from Cinachyrella sp. (ball sponge). Acta Crystallogr2012
- Author(s)
  Freymann, D. M.; Nakamura, Y.; Focia, P. J.; Sakai, R.; Swanson, G. T.
- Journal Title
  
  D, Biol. Cryst
  
  Volume: 68 Issue: 9 Pages: 1163-74
- DOI
  10.1107/s0907444912022834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114, KAKENHI-PUBLICLY-23108503
[Journal Article] Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors2011
- Author(s)
  Unno, M.; Shinohara, M.; Takayama, K.; Tanaka, H.; Teruya, K.; Doh-Ura, K.; Sakai, R.; Sasaki, M.; Ikeda-Saito, M.
- Journal Title
  
  J. Mol. Biol
  
  Volume: (DOI:S0022-2836(11)00955-7[pii])
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114
[Journal Article] Isolation, amino acid sequence and biological activities of novel long-chain polyamine-associated peptide toxins from the sponge Axinyssa aculeata2011
- Author(s)
  Matsunaga, S.; Jimbo, M.; Gill, M. B.; Wyhe, L. L.; Murata, M.; Nonomura, K.; Swanson, G. T.; Sakai, R.
- Journal Title
  
  Chembiochem
  
  Volume: 12 Issue: 14 Pages: 2191-200
- DOI
  10.1002/cbic.201100329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114
[Journal Article] Isolation, amino acid sequence and biological activities of novel long-chain polyamine-associated peptide toxins from the sponge Axinyssa aculeata2011
- Author(s)
  Matsunaga, S., Jimbo, M., Gill, M.B., Wyhe, L.L., Murata, M., Nonomura, K., Swanson, G.T., Sakai, R.
- Journal Title
  
  Chembiochem
  
  Volume: 14 Issue: 14 Pages: 2191-2200
- DOI
  10.1002/cbic.201190063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114, KAKENHI-PUBLICLY-23108503
[Journal Article] 中枢神経系GABA受容体の機能を調節する有機化合物2011
- Author(s)
  M.Sakai, S.Sasaki, M.Oikawa
- Journal Title
  
  横浜市立大学論叢(自然科学系列)
  
  Volume: 61 Pages: 75-89
- NAID
  120005670476
- Data Source
  KAKENHI-PROJECT-21603004
[Journal Article] Novel N-Methylated 8-Oxoisoguanines from Pacific Sponges with Diverse Neuroactivities2010
- Author(s)
  Tsuyoshi Sakurada, Martin B.Gill, Shanti Frausto, Bryan Copits, Keiichi Noguchi, Keiko Shimamoto, Geoffrey T.Swanson, Ryuichi Sakai
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 53 Pages: 6089-6099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114
[Journal Article] Novel N-methylated 8-oxoisoguanines from Pacific sponges with diverse neuroactivities2010
- Author(s)
  Sakurada, T.; Gill, M. B.; Frausto, S.; Copits, B.; Noguchi, K.; Shimamoto, K.; Swanson, G. T.; Sakai, R.
- Journal Title
  
  J. Med. Chem
  
  Volume: 53 Issue: 16 Pages: 6089-99
- DOI
  10.1021/jm100490m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380114
[Journal Article] A series of structurally novel heterotricyclicα-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor-selective antagonists2010
- Author(s)
  M. B. Gill, S. Frausto, M. Ikoma, M. Sasaki, M. Oikawa, R. Sakai, G. T. Swanson
- Journal Title
  
  Br J Pharmacol
  
  Volume: 160 Issue: 6 Pages: 1417-1429
- DOI
  10.1111/j.1476-5381.2010.00784.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603004
[Journal Article] Improved synthesis and in vitro/in vivo activities of natural product-inspired, artificial glutamate analogs2010
- Author(s)
  M. Oikawa, M. Ikoma, M. Sasaki, M. B. Gill, G. T. Swanson, K. Shimamoto, R. Sakai
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 18 Issue: 11 Pages: 3795-3804
- DOI
  10.1016/j.bmc.2010.04.044
- NAID
  120002169301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603004
[Journal Article] Regioselective Domino Metathesis of Unsymmetrical 7-Oxanorbornenes with Electron-rich Vinyl Acetate toward Biologically Active Glutamate Analogues2009
- Author(s)
  M. Oikawa, M. Ikoma, M. Sasaki, M. B. Gill, G. T. Swanson, K. Shimamoto, R. Sakai
- Journal Title
  
  Eur. J. Org. Chem
  
  Volume: 2009 Issue: 32 Pages: 5531-5548
- DOI
  10.1002/ejoc.200900580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603004
[Journal Article] Cellular Origin of Dysiherbaine an Excitatory Amino Acid Derived from a Marine Sponge2008
- Author(s)
  Sakai, R., Yoshida, K., Kimura, A., Koike, K., Jimbo, M., Koike, K., Kobiyama, A., Kamiya, H
- Journal Title
  
  ChemBioChem 9
  
  Pages: 543-551
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] Cellular origin of dysiherbaine,an excitatory amino acid derived from a marine sponge2008
- Author(s)
  Sakai R, Yoshida K, Kimura A, Koike K, Jimbo M, Koike K, Kobiyama A and Kamiya H
- Journal Title
  
  ChemBioChem 9
  
  Pages: 543-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] Cellular origin of dysiherbaine,an excitatory amino acid derived from amarine sponge2008
- Author(s)
  Sakai R, Yoshida K, Kimura A, Koike K, Jimbo M, Koike K, Ko biyama A and Kamiya H
- Journal Title
  
  ChemBioChem 9
  
  Pages: 543-551
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] Long-Chain Polyamines (LCPAs) from Marine Sponge : Possible Implication in Spicule Formation2007
- Author(s)
  Matsunaga, S., Sakai, R., Jimbo, M., Kamiya, H
- Journal Title
  
  ChemBioChem 8
  
  Pages: 1729-1735
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] Long-chain polyamines(LCPAs)from marine sponge:possible implication in spicule formation2007
- Author(s)
  Matsunaga S, Sakai R, Jimbo M and Kamiya H
- Journal Title
  
  ChemBioChem 8
  
  Pages: 1729-1735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] Long-chain polyamines (LCPAs) from marine sponge:possible implication in spicule formation2007
- Author(s)
  Matsunaga S, Sakai R, Jimbo Mand Kamiya H
- Journal Title
  
  ChemBioChem 8
  
  Pages: 1729-1735
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] 1-Deoxynojirimycin derivatives from the marine sponge Lendenfeldia chondrodes2006
- Author(s)
  R.Sakai, H.Kamiya
- Journal Title
  
  Journal of Antibiotics 59
  
  Pages: 507-511
- NAID
  10018040502
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] Total synthesis and biological evaluation of neodysiherbaine A and analogues2006
- Author(s)
  M.Shoji, N.Akiyama, K.Tsubone, L.L.Lash, J.M.Sanders, G.T.Swanson, R.Sakai, K.Shimamoto, M.Oikawa, M.Sasaki
- Journal Title
  
  The Journal of Organic Chemistry 71
  
  Pages: 5208-5220
- Data Source
  KAKENHI-PROJECT-16073202
[Journal Article] Dysiherbaine : A new generation of excitatory amino acids of marine origin2006
- Author(s)
  Sakai, R., Swanson, GT., Sasaki, M., Shimamoto, K., Kamiya, H
- Journal Title
  
  Current Medicinal Chemistry-Central Nervous System Agents 6
  
  Pages: 83-108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] 1-Deoxynojirimycin Derivatives from the Marine Sponge2006
- Author(s)
  Sakai, R., Kamiya, H
- Journal Title
  
  Lendenfeldia chondrodes J. Antibiot 59
  
  Pages: 507-511
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] Dysiherbaine:A new generation of excitatory amino acids of marine origin2006
- Author(s)
  Sakai R, Swanson GT, Sasaki M, Shimamoto K, Kamiya H.
- Journal Title
  
  Current Medicinal Chemistry-Central Nervous System Agents 6
  
  Pages: 83-108
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] 1-Deoxynoiirimycin derivatives from the marine sponge Lendenfeldia chondrodes2006
- Author(s)
  R.Sakai and H.Kamiya
- Journal Title
  
  Journal of Antibiotics 59
  
  Pages: 507-511
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380125
[Journal Article] Design, total synthesis, and biological evaluation of neodysiherbaine A derivative as potential probes2006
- Author(s)
  M.Sasaki, K.Tsubone, M.Shoji, M.Oikawa, K.Shimamoto, R.Sakai
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry Letters 16
  
  Pages: 5784-5787
- Data Source
  KAKENHI-PROJECT-16073202
[Journal Article] Dysiherbaine : a new generation of excitatory amino acids of marine origin2006
- Author(s)
  R.Sakai, G.T.Swanson, M.Sasaki, K.Shimamoto, H.Kamiya
- Journal Title
  
  Central Nervous System Agents in Medicinal Chemistry 6
  
  Pages: 83-108
- Data Source
  KAKENHI-PROJECT-16073202
[Journal Article] Determination of binding site residues responsible for the subunit selectivity of novel marine-derived compounds on kainate receptors2006
- Author(s)
  J.M.Sanders, O.T.Pentikainen, L.Settimo, U.Pentikainen, M.Shoji, M.Sasaki, R.Sakai, M.S.Johnson, G.T.Swanson
- Journal Title
  
  Molecular Pharmacology 69
  
  Pages: 1849-1860
- Data Source
  KAKENHI-PROJECT-16073202
[Journal Article] Synthesis of dysiherbaine analogue2005
- Author(s)
  M.Shoji, K.Shiohara, M.Oikawa, R.Sakai, M.Sasaki
- Journal Title
  
  Tetrahedron Letters 46(33)
  
  Pages: 5559-5562
- Data Source
  KAKENHI-PROJECT-16073202
[Journal Article] Cloning and characterization of a lectin from the octocoral Sinularia lochmodes.2005
- Author(s)
  Jimbo, M, K.Koike, R.Sakai, K.Muramoto, H.Kamiya
- Journal Title
  
  Biochem.Biophys.Res.Commun. 330
  
  Pages: 157-162
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380145
[Journal Article] Cloning and characterization of a lectin from the octocoral Sinularia lochmodes.2005
- Author(s)
  M.Jimho, K.Koike, R.Sakai, K.Muramoto, H.Kamiya
- Journal Title
  
  Biochem.Biophys.Res.Commun. 330
  
  Pages: 157-162
- Data Source
  KAKENHI-PROJECT-15380145
[Journal Article] Divergent pharmacological activity of novel marine-derived excitatory amino acids on glutamate receptors2005
- Author(s)
  J.M.Sanders, K.Ito, L.Settimo, O.T.Pentikainen, M.Shoji, M.Sasaki, M.S.Johnson, R.Sakai, G.T.Swanson
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 314(3)
  
  Pages: 1068-1078
- Data Source
  KAKENHI-PROJECT-16073202
[Journal Article] Cloning and characterization of a lectin from the octocoral Sinularia lochmodes.2005
- Author(s)
  Jimbo, M, K.Koike, R.Sakai, K.Muramoto, H.Kamiya
- Journal Title
  
  Biochem. Biophys. Res. Commun. 330
  
  Pages: 157-162
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380145
[Journal Article] Cellular localization of dysiherbaine in Dysidea herbacea.2004
- Author(s)
  R.Sakai, K.Yoshida, K.Koike, A.Kimura
- Journal Title
  
  XI International Symposium on Marine Natural Products. Sorrento, Italy, Proceedings
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Cellular localization of dysiherbaine in Dysidea herbacea.2004
- Author(s)
  R.Sakai, K.Yoshida, K.Koike, A.Kimura, M.Jimbo, S.Minato, H.Kamiya
- Journal Title
  
  XI International Symposium on Marine Natural Products. Sorrento, Italy, Proceedings
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Cellular and subcellular localizations of kainic acid in Digenea simplex.2004
- Author(s)
  S.Minato, R.Sakai, K.Koike, K.Koike, M.Jimbo.H.Kamiya
- Journal Title
  
  XI International Symposium on Marine Natural Products. Sorrento, Italy, Proceedings
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Physiological study of Dysiherbaine, a Marine-Derived Excitatory Amino Acid2004
- Author(s)
  R.Sakai, G.T.Swanson, K.Shimamoto, H.Kamiya
- Journal Title
  
  Japanese Journal of Physiology 54(Suppl)
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Cellular and subcellular localization of kainic acid in Digenea simplex.2004
- Author(s)
  S.Minato, R.Sakai, K.Koike, K.Koike, M.Jimbo, H.Kamiya
- Journal Title
  
  XI International Symposium on Marine Natural Products, Proceedings
  
  Pages: 95-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Octocoral chemical signaling selects and controls dinoflagellates symbionts.2004
- Author(s)
  Koike, K., M.jimbo, R.Sakai, M.kaeriyama, K.Muramoto, T.Ogata, T.Maruyama, H.Kamiya
- Journal Title
  
  Biol. Bull. 207
  
  Pages: 80-86
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380145
[Journal Article] Cellular and subcellular localizations of kainic acid in Digenea simplex.2004
- Author(s)
  S.Minato, R.Sakai, K.Koike, K.Koike, M.Jimbo, H.Kamiya
- Journal Title
  
  XI International Symposium on Marine Natural Products. Sorrento, Italy, Proceedings
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Cellular localization of dysiherbaine in Dysidea herbacea.2004
- Author(s)
  R.Sakai, K.Yoshida, K.Koike, A.Kimura, M.Jimbo, S.Minato, H.Kamiya
- Journal Title
  
  XI International Symposium on Marine Natural Products, Proceedings O25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Octocoral chemical signaling selects and controls dinoflagellates symbionts.2004
- Author(s)
  Koike, K., M.Jimbo, R.Sakai, M.Kaeriyama, K.Muramoto, T.Ogata, T.Maruyama, H.Kamiya
- Journal Title
  
  Biol.Bull. 207
  
  Pages: 80-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380145
[Journal Article] Physiological study of Dysiherbaine, a Marine-Derived Excitatory Amino Acid.2004
- Author(s)
  R.Sakai, G.T.Swanson, K.Shimamoto, H.Kamiya
- Journal Title
  
  Japanese Journal of Physiology 54(Suppl)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Physiological study of Dysiherbaine, a Marine-Derived Excitatory Amino Acid2004
- Author(s)
  R.Sakai, G.T.Swanson, K.Shimamoto H.Kamiya
- Journal Title
  
  Japanese Journal of Physiology 54(Suppl)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Cellular localization of dysiherbaine in the producing organism2003
- Author(s)
  R.Sakai, K.Yoshida, K.Koike, M.Jimbo, S.Minato, H.Kamiya
- Journal Title
  
  The 45^<th> Symposium on the chemistry of natural products. Kyoto Symposium paper
  
  Pages: 629-634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] 興奮性アミノ酸ダイシハーベインの組織内局在性:産生生物と存在意義の解明に向けて2003
- Author(s)
  酒井隆一, 吉田和史, 小池香苗, 神保充, 小池和彦, 湊早樹子, 神谷久男
- Journal Title
  
  第45回天然有機化合物討論会講演要旨集
  
  Pages: 629-634
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580183
[Journal Article] Marine Molecular Biotechnology Marine Toxins as Research Tools
- Author(s)
  Swanson, GT., Sakai, R
- Journal Title
  
  (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Patent] フコ―ス結合型レクチンを含む抗ウイルス剤2022
- Inventor(s)
  酒井隆一、田中良和、高田礼人
- Industrial Property Rights Holder
  酒井隆一、田中良和、高田礼人
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19H03040
[Patent] 機能性ポリペプチドおよびその使用2020
- Inventor(s)
  酒井隆一
- Industrial Property Rights Holder
  酒井隆一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-069328
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H03040
[Patent] 機能性ポリペプチド及びその利用2020
- Inventor(s)
  酒井隆一、中野宏冶
- Industrial Property Rights Holder
  酒井隆一、中野宏冶
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H03040
[Patent] 機能性ポリペプチド及びその利用2020
- Inventor(s)
  酒井隆一、中野宏冶
- Industrial Property Rights Holder
  酒井隆一、中野宏冶
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PUBLICLY-18H04600
[Patent] 機能性ポリペプチドおよびその使用2020
- Inventor(s)
  酒井隆一
- Industrial Property Rights Holder
  酒井隆一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-069328
- Filing Date
  2020
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Patent] NU2014-033, title : A Novel 5-HT5A Receptor Antagonist for Treatment of Psychiatric Diseases2014
- Inventor(s)
  Ryuichi Sakai, Hajime Uhimasu, Geoffrey T. Swanson
- Industrial Property Rights Holder
  Northwestern University
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-04
- Overseas
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Isolation, Characterization and Bioactivity of a New Marine Sponge Lectin2023
- Author(s)
  Sobia Nasir、澤田祐二、辺　浩美、酒井隆一
- Organizer
  日本水産学会　年会
- Data Source
  KAKENHI-PROJECT-23K23695
[Presentation] 海綿由来レクチンをプローブとしたサイトカイン受容体新規活性化機構の解明2022
- Author(s)
  辺浩美, 影山大夢, 中島寛弥, 小野寺かこ, 増渕菜弥, 大城拓未, 松井崇, 小寺義男, 小川智久, 平山真, 堀貫治, 横山武司, 小松則夫, 小松則夫, 荒木真理人, 荒木真理人, 田中良和, 酒井隆一
- Organizer
  天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-23K23695
[Presentation] Studies toward synthesis of aculeine B, a cytotoxic peptide-polyamine conjugate from marine sponges.2021
- Author(s)
  Oikawa. M, Miyahara M.; Nakamura S.; Honda A.; *Sakai R; Irie Y.; Irie K.; Irie
- Organizer
  PACIFICHEM2021, Online, Dec 19-21.
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] Identification of the mycalolides biosynthetic bacterium from the marine sponge genus Mycale2021
- Author(s)
  Fujita M; Takada K; Yoshitake K; Ise Y; Kimura, N.; Fukuoka, M; Ninomiya, A.; Sakai R
- Organizer
  PACIFICHEM2021, Online, Dec 19-21.
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] 有害外来種ヨーロッパザラボヤに含まれるフェロモン様物質の探索2021
- Author(s)
  宮古圭, 酒井隆一
- Organizer
  日本水産学会大会
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Presentation] Marine natural products as markers for elucidating biological relationships in coral reef ecosystems2021
- Author(s)
  Yamashita Hiroshi, Sakai Ryuichi, Ikeda Hiroki, Jimbo Mitsuru, Shinzato Chuya, Suzuki Go, Fukuoka Koki, Goto-Inoue Naoko
- Organizer
  Pacifichem2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04742
[Presentation] Chemical and biological aspects of water-soluble marine natural products.2021
- Author(s)
  R.Sakai
- Organizer
  The 36th Symposium on Natural Products, Taiwan, Oct 15-16, Online.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Presentation] Metabolomics-mass imaging approach reveals ‘smart use’ of metabolites in giant clam Tridacna crocea2021
- Author(s)
  Ikeda Hiroki, Goto-Inoue Naoko, Maruyama Tadashi, Yamashita Hiroshi, Sakai Ryuichi
- Organizer
  Pacifichem2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04742
[Presentation] 有害外来種ヨーロッパザラボヤに含まれるフェロモン様物質の探索2021
- Author(s)
  宮古圭, 酒井隆一
- Organizer
  日本水産学会大会
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] Identification of the mycalolides biosynthetic bacterium from the marine sponge genus Mycale2021
- Author(s)
  Fujita M; Takada K; Yoshitake K; Ise Y; Kimura, N.; Fukuoka, M; Ninomiya, A.; Sakai R
- Organizer
  PACIFICHEM2021, Online, Dec 19-21.
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Presentation] Activation of thrombopoietin receptor by sponge derived protein: Novel mechanism of activation of c Mpl2021
- Author(s)
  Watari, H; Onodera, K, Kageyama, H, Masubuchi, N, Araki, M, Tanaka, Y, Komatsu, N, Sakai, R
- Organizer
  PACIFICHEM2021, Online, Dec 19-21.
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] Chemical and biological aspects of water-soluble marine natural products. The 36th Symposium on Natural Products2021
- Author(s)
  Sakai R
- Organizer
  The 36th Symposium on Natural Products, Taiwan, Oct 15-16, Online.
- Invited
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] Metabolomics-mass imaging approach reveals ‘smart use’ of metabolites in giant clam Tridacna crocea2021
- Author(s)
  Ikeda, H; Goto-Inoue, N; Maruyama, T; Yamashita H; Sakai R
- Organizer
  PACIFICHEM2021, Online, Dec 19-21.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Presentation] Diverse aromatic metabolites in the solitary tunicate Cnemidocarpa irene.2021
- Author(s)
  Miyako K., Yasuno Y.; Shinada T.; Sakai R
- Organizer
  PACIFICHEM2021, Online, Dec 19-21.
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] 海洋性海綿動物レクチンはMPLの糖鎖仲介活性化の機構を明らかにする2021
- Author(s)
  辺浩美, 影山大夢, 中島寛弥, 小野寺かこ, 増渕菜弥, 大城拓未, 松井崇, 小寺義男, 小川智久, 平山真, 堀貫治, 横山武司, 小松則夫, 小松則夫, 荒木真理人, 荒木真理人, 田中良和, 酒井隆一
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] Diverse aromatic metabolites in the solitary tunicate Cnemidocarpa irene.2021
- Author(s)
  Miyako K., Yasuno Y.; Shinada T.; Sakai R
- Organizer
  PACIFICHEM2021, Online, Dec 19-21.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Presentation] Metabolomics-mass imaging approach reveals ‘smart use’ of metabolites in giant clam Tridacna crocea2021
- Author(s)
  Ikeda, H; Goto-Inoue, N; Maruyama, T; Yamashita H; Sakai R
- Organizer
  PACIFICHEM2021, Online, Dec 19-21.
- Invited
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] A sponge protein toxin that travels to cell nucleus2020
- Author(s)
  酒井隆一
- Organizer
  Institute of Marine Biotechnology (IMB) and Japan Online International Exchange Symposium on Aquatic Science Research, 16th November 2020.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Presentation] 網羅的代謝物解析で探るシャコガイ-褐虫藻共生生物系の適応戦略2020
- Author(s)
  池田広樹、井上菜穂子、佐藤友彦、森笹瑞希、山下洋、丸山正、酒井隆一
- Organizer
  第62回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-18H02270
[Presentation] 細胞のバリアを攻略する海洋天然物の探索2020
- Author(s)
  酒井隆一
- Organizer
  日本化学会第100回春季年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04600
[Presentation] ヒメジャコTridacna croceaの外套膜における紫外線吸収物質の局在の研究2020
- Author(s)
  井上菜穂子，佐藤友彦，森笹瑞季，山下洋，丸山正，池田広樹，酒井隆一
- Organizer
  令和2年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-18H02270
[Presentation] 細胞のバリアを攻略する海洋天然物の探索.2020
- Author(s)
  酒井隆一
- Organizer
  日本化学会第100回年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04758
[Presentation] 細胞のバリアを攻略する海洋天然物の探索.2020
- Author(s)
  酒井隆一
- Organizer
  日本化学会第100回年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] A sponge protein toxin that travels to cell nucleus.2020
- Author(s)
  Ryuichi Sakai,
- Organizer
  Institute of Marine Biotechnology (IMB) and Japan Online International Exchange Symposium on Aquatic Science Research, 16th November 2020.
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] 細胞のバリアを攻略する海洋天然物の探索2020
- Author(s)
  酒井隆一
- Organizer
  日本化学会第100回春季年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03040
[Presentation] 海洋生物のポリカチオンコミュニケーション戦略2019
- Author(s)
  酒井隆一
- Organizer
  化学コミュニケーションのフロンティア　第6回公開シンポジウム
- Data Source
  KAKENHI-PUBLICLY-18H04600
[Presentation] サンゴ礁における褐虫藻の役割2019
- Author(s)
  山下洋，酒井隆一，池田広樹，神保充，新里宙也，鈴木豪，福岡弘紀，井上菜穂子
- Organizer
  令和元年度環境研究機関研究交流セミナー
- Data Source
  KAKENHI-PROJECT-18H02270
[Presentation] 海綿由来蛋白質ThCによるトロンボポエチン受容体の活性化機構2019
- Author(s)
  辺浩美、中島寛弥、渥海航、酒井隆一
- Organizer
  平成31年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] 天然物化学的手法を用いたサンゴ礁の代謝物フローの解析2019
- Author(s)
  池田広樹，山下洋，酒井隆一
- Organizer
  第61回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-18H02270
[Presentation] KB343, a cyclic tris-guanidine alkaloid from Palauan Zoantharian Epizoanthus illoricatus2019
- Author(s)
  K. Matsumura, T. Taniguchi, J. Reimer, S. Noguchi, M. Fujita, R. Sakai
- Organizer
  "新学術領域研究「化学コミュニケーションのフロンティア」第1回国際シンポジウム The 1st International Symposium on Chemical Communication (ISCC2019)"
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04600
[Presentation] 天然物化学的手法を用いた褐虫藻代謝物の網羅的解析―サンゴ礁の食物網解明を目指して―2019
- Author(s)
  池田広樹，山下洋，酒井隆一
- Organizer
  平成31年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-18H02270
[Presentation] 単体ボヤCnemidocarpa ireneより得られた芳香族化合物の構造と機能2018
- Author(s)
  宮古圭、保野洋子、品田哲郎、藤田雅紀、酒井隆一
- Organizer
  平成30年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] 西表産Spongosorites属海綿由来の新規タンパク質毒素の作用機構2018
- Author(s)
  飯田祐介、中野宏治、上田拓也、北野雅也、藤田雅紀、酒井隆一
- Organizer
  平成30年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] 細胞表面の「生命装置」に作用する水溶性海洋天然物の探索(低分子編)2018
- Author(s)
  酒井隆一
- Organizer
  天然薬物の開発と応用シンポジウム講演要旨集 22nd 1‐4
- Invited
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] パラオ産Epizoanthus illoricatusより得られた新規トリスグアニジンアルカロイドの構造と生理活性2018
- Author(s)
  松村賢、谷口透、J. Reimer, 野口峻太朗、藤田雅紀、酒井隆一
- Organizer
  第60回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] パラオ産Epizoanthus illoricatusより得られた新規トリスグアニジンアルカロイドの構造と生理活性2018
- Author(s)
  松村賢、谷口透、J. Reimer, 野口峻太朗、藤田雅紀、酒井隆一
- Organizer
  第60回天然有機化合物討論会
- Data Source
  KAKENHI-PUBLICLY-18H04600
[Presentation] Bioactive alkaloids from a solitary ascidian Cnemidocarpa irene2017
- Author(s)
  Kei Miyako, Youhei Tadokoro, Taichi Ichimori, Masaki J Fujita, Ryuichi Sakai
- Organizer
  International Symposium: Fisheries Science for Future Generations
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] A novel sponge-derived protein Thrombocorticin with thrombopoietin-like activity2017
- Author(s)
  Hiromi Watari, Hiroya Nakajima, Wataru Atsuumi, Takanori Nakamura, Takeshi Nanya Masaki J Fujita, Ryuichi Sakai
- Organizer
  International Symposium: Fisheries Science for Future Generations
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] 単体ボヤCnemidocarpa ireneに含まれる生理活性アルカロイドの探索2017
- Author(s)
  宮古圭、田所洋平、市森大地、藤田雅紀、酒井隆一
- Organizer
  第59回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] パラオ産Didemnidae科ホヤに含まれる新規神経活性物質グアニジンアルカロイドとその関連化合物に関する研究2017
- Author(s)
  松村賢、内舛肇、藤田雅紀、酒井隆一、津田正史、熊谷慶子、赤壁麻衣
- Organizer
  日本水産学会春季大会
- Place of Presentation
  東京海洋大学（東京都港区）
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] Novel guanidine alkaloids from an aqueous extract of Palauan Epizoanthus sp2017
- Author(s)
  Ken Matsumura, Masaki J Fujita, James Reimer, Ryuichi Sakai
- Organizer
  International Symposium: Fisheries Science for Future Generations
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] Bioactive metabolites from water-soluble marine extracts.2017
- Author(s)
  Ryuichi Sakai
- Organizer
  American Society of Pharmacognosy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] カテキンの構造がサケ (Oncorhynchus keta) の卵膜軟化症防除効果に与える影響2017
- Author(s)
  小松代祐生，記内　優，松本善行，大久保　勉，伴　真俊，中山　勉，酒井隆一，笠井久会
- Organizer
  平成29年度日本魚病学会春季大会
- Place of Presentation
  日本大学（神奈川県藤沢市）
- Year and Date
  2017-03-11
- Data Source
  KAKENHI-PROJECT-16H04964
[Presentation] Soritesidine: A potent protein toxin from the marine sponge Spongosorites sp.2016
- Author(s)
  酒井隆一
- Organizer
  8th US-JAPAN symposium on Marine Natural Products
- Place of Presentation
  ハワイ大学癌研究所、米国　ホノルル市
- Year and Date
  2016-11-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12750
[Presentation] Soritesidine: A potent protein toxin from the marine sponge Spongosorites sp2016
- Author(s)
  Ryuichi Sakai
- Organizer
  US-JAPAN symposium on marine natural products
- Place of Presentation
  ハワイ大学癌研究所　米国　ホノルル市
- Year and Date
  2016-11-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] 西表島産Spongosorites属海綿に含まれるタンパク質毒素の分離2016
- Author(s)
  酒井隆一, 中野宏治, 上田拓也, 北野雅也, 小野巧, 棚野豪太, 神保充, 藤田雅紀
- Organizer
  平成28年度日本水産学会年会
- Place of Presentation
  東京海洋大学、（東京都、港区）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] 北海道産単体ボヤCnemidcarpa ireneに含まれる生理活性物質に関する研究2016
- Author(s)
  田所洋平、酒井隆一、西川輝明、藤田雅紀
- Organizer
  平成28年度日本水産学会年会
- Place of Presentation
  東京海洋大学　（東京都、港区）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] 海綿毒素ソリテシジンの研究2015
- Author(s)
  酒井隆一
- Organizer
  第62回トキシンシンポジウム
- Place of Presentation
  エクシード合歓、賢島　(三重県、志摩市)
- Year and Date
  2015-07-08
- Invited
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] パラオ産 Didemnidae科ホヤ由来新規神経活性化合物群Mellpaladine類に関する研究2015
- Author(s)
  内升肇、松村賢、津田正史、熊谷慶子、赤壁舞依、藤田雅紀、酒井隆一
- Organizer
  第57回天然有機化合物討論会
- Place of Presentation
  神奈川県民ホール　（神奈川県、横浜市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-15H04546
[Presentation] Aculeaine　Aの溶血活性2014
- Author(s)
  岸伶美、酒井隆一
- Organizer
  日本水産学会
- Place of Presentation
  北海道大学函館キャンパス　函館市
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Aculeine A の溶血活性2014
- Author(s)
  岸伶美, 酒井隆一
- Organizer
  日本水産学会大会
- Place of Presentation
  北海道大学函館キャンパス,函館
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] パラオ産海綿Axinyssa sp.より得られたグルタミン酸受容体作動薬に関する研究内舛肇2014
- Author(s)
  Eng A., Ekins M., Hooper J., Swanson G.T., 酒井隆一
- Organizer
  日本水産学会大会
- Place of Presentation
  北海道大学函館キャンパス,函館
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] パラオ産海綿Axinyssa sp.より得られたグルタミン酸受容体作動薬に関する研究2014
- Author(s)
  内舛　肇、Andrew Engb, Millick Ekins, John Hooper, Geoffrey T. Swanson, 酒井　隆一
- Organizer
  日本水産学会
- Place of Presentation
  北海道大学函館キャンパス　函館市
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] 海綿Axinyssa aculeata 由来の長鎖ポリアミン化合物Protoaculeine B の構造解析2013
- Author(s)
  松永智子, 酒井隆一
- Organizer
  日本水産学会大会
- Place of Presentation
  東京海洋大学東京
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Aculeines : Novel peptide toxins modified with long chain polyamine from the Okinawan marine sponge2013
- Author(s)
  Sakai R, Kishi R., Matsunaga S
- Organizer
  MaNaPro2013
- Place of Presentation
  Hesperia La Toja Hotel, La Toja Island, Spain
- Year and Date
  2013-09-16
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Aculaines: Novel peptide toxins modified with long chain polyamine from the Okinawan marine sponge.2013
- Author(s)
  Ryuichi Sakai, Reimi Kishi, Satoko Matsunaga
- Organizer
  MaNaPro2013
- Place of Presentation
  Hesperia La Toja Hotel, La Toja Island, Spain
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] 海綿Cinachyrella sp.から得られたiGluR 制御活性を示す新規ガレクチンの研究2013
- Author(s)
  上田拓弥, Freymann DM, Focial PJ,中村友香, Smith C, 井上昌, 尾島孝男, 松永智子, Swanson GT, 酒井隆一
- Organizer
  日本水産学会大会
- Place of Presentation
  東京海洋大学東京
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Neuroactive small molecules from water soluble extracts of Palauan sponge and tunicate2013
- Author(s)
  Hajime Uchimasu , Andrew Eng, Geoffrey Swanson, Ryuichi Sakai
- Organizer
  MaNaPro2013
- Place of Presentation
  Hesperia La Toja Hotel, La Toja Island, Spain
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Neuroactive small molecules from water soluble extracts of Palauan sponges and tunicates2013
- Author(s)
  Uchimasu H., Eng A., Swanson GT, Sakai R
- Organizer
  MaNaPro 2013
- Place of Presentation
  Hesperia La Toja Hotel, La Toja Island, Spain
- Year and Date
  2013-09-16
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Bioactive rebosomal peptides from marine sponges2012
- Author(s)
  酒井隆一
- Organizer
  Gordon research conference
- Place of Presentation
  Ventura Beach Marriott(米国)(招待講演)
- Year and Date
  2012-02-27
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] 海綿由来興奮性アミノ酸ダイシハーベイン2012
- Author(s)
  酒井隆一
- Organizer
  日本薬学会年会
- Place of Presentation
  北海道大学,札幌
- Year and Date
  2012-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] 興奮性アミノ酸ダイシハーベインの研究2012
- Author(s)
  酒井隆一
- Organizer
  第132回日本薬学会年会
- Place of Presentation
  北海道大学(札幌)(招待講演)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] 興奮性アミノ酸ダイシハーベインの研究2012
- Author(s)
  酒井隆一
- Organizer
  第132回日本薬学会年会
- Place of Presentation
  北海道大学(札幌)(招待講演)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PUBLICLY-23108503
[Presentation] 海綿ー共生微生物複合体由来の小分子生合成マシナリーの探索2012
- Author(s)
  酒井隆一
- Organizer
  生合成マシナリ-　第4回公開シンポジウム
- Place of Presentation
  東京大学(東京都）
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PUBLICLY-23108503
[Presentation] Novel Neuroactive Compounds From Aqueous Extracts of Marine Sponges.2012
- Author(s)
  酒井隆一
- Organizer
  American Chemical Society Meeting
- Place of Presentation
  ペンシルバニア州フィラデルフィア（USA)
- Year and Date
  2012-08-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-23108503
[Presentation] Toward the biosynthetic origin of dysiherbaine2012
- Author(s)
  酒井隆一
- Organizer
  The International conference of natural products biosynthesis
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Year and Date
  2012-06-17
- Data Source
  KAKENHI-PUBLICLY-23108503
[Presentation] Biologically active ribosomal peptides from sponges2012
- Author(s)
  Sakai R
- Organizer
  Gordon Research Conference on Marine Natural Products
- Place of Presentation
  Ventura CA
- Year and Date
  2012-02-27
- Invited
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Novel neuroactive compounds from aqueous extracts of marine sponges2012
- Author(s)
  Sakai R
- Organizer
  American Chemical Society Meeting
- Place of Presentation
  Philadelphia, PA
- Year and Date
  2012-08-19
- Invited
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Bioactive rebosomal peptides from marine sponges2012
- Author(s)
  酒井隆一
- Organizer
  Gordon research conference
- Place of Presentation
  Ventura Beach Marriott(米国)(招待講演)
- Year and Date
  2012-02-27
- Data Source
  KAKENHI-PUBLICLY-23108503
[Presentation] パラオ産海綿より得られた新規プリン化合物の構造と神経調節活性2011
- Author(s)
  櫻田剛史, Gill M.B., Frausto S., Copits B., 野口恵一, 島本啓子, Swanson GT., 酒井隆一
- Organizer
  日本水産学会大会
- Place of Presentation
  東京海洋大学東京
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Aculeine およびその類縁体の構造解析2011
- Author(s)
  松永智子, 酒井隆一, Gill M.B., Lash‐Van Wyhe L.L., Swanson GT
- Organizer
  天然有機化合物討論会
- Place of Presentation
  大阪国際交流センター大阪
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] 沖縄県産海綿Cinachyrella sp.より得られたガレクチンIRI35 の配列解析2011
- Author(s)
  上田拓弥, 井上昌, 中村友香, 松永智子,尾島孝男, Swanson GT., 酒井隆一
- Organizer
  日本水産学会大会
- Place of Presentation
  長崎大学,長崎市
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Aculeineおよびその類縁体の構造解析2011
- Author(s)
  松永智子、酒井隆一、Gill, M.B., Lash, Van-Wyhe, L.L., Swanson G.T.
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪国際センター(大阪)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] US-Japan Seminar for Marine Natural Products2011
- Author(s)
  Sakai R
- Organizer
  Okinawa
- Invited
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Novel peptide toxins from marine sponges2011
- Author(s)
  酒井隆一
- Organizer
  第7回US-JAPANセミナー
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)(招待講演)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PUBLICLY-23108503
[Presentation] Aculeine 類およびその類縁体の構造解析2011
- Author(s)
  松永智子, 酒井隆一
- Organizer
  日本水産学会大会
- Place of Presentation
  東京海洋大学,東京
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] 沖縄県産海綿Cinachyrella sp.より得られたガレクチンIRI35の配列解析2011
- Author(s)
  上田拓弥・井上昌・中村友香・松永智子・尾島孝男・Geffrey T.Swanson・酒井隆一
- Organizer
  日本水産学会秋季年会
- Place of Presentation
  長崎大学(長崎)
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Novel peptide toxins from marine sponges2011
- Author(s)
  酒井隆一
- Organizer
  第7回US-JAPANセミナー
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)(招待講演)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] パラオ産Haplosclerida 海綿より得られた新規プリンの構造と神経調節活性2010
- Author(s)
  櫻田剛史, Gill M. B., Frausto S., Copits B., 野口恵一, 島本啓子, Swanson G.T.,酒井隆一
- Organizer
  天然有機化合物討論会
- Place of Presentation
  静岡コンベンションアーツセンター,静岡
- Year and Date
  2010-09-30
- Data Source
  KAKENHI-PROJECT-22380114
[Presentation] Isolation of novel polyamines from the Marine sponge Axinyssa aculeata : possible role in sponge spicule formation2007
- Author(s)
  Ryuichi, Sakai, Satoko, Matsunaga, Mitsuru, Jimbo, Hisao, Kamiya
- Organizer
  The Japanese Society of Fisheries Sciences, 2007 annual meeting
- Place of Presentation
  Tokyo University of Marine Science and Technology
- Year and Date
  2007-04-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] 海綿Axinyssa aculeataより得られた新規神経毒ペプチドの分離と精製2007
- Author(s)
  松永智子, 酒井隆一, 神保充, 神谷久男
- Organizer
  平成19年度日本水産学会春季大会
- Place of Presentation
  東京海洋大学
- Year and Date
  2007-04-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Chemical Biology of Neuroactive Sponge Metabolites2007
- Author(s)
  Sakai R, Matsunaga S, Kimura A, Koike K, Koike K, Jimbo M, Kamiya H.
- Organizer
  VIth US-Japan Seminar:Frontiers in Marine Natural Products Research
- Place of Presentation
  Park City,Utah,U.S.A.
- Year and Date
  2007-07-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Cellular localization of excitatory amino acid dysiherbaine2007
- Author(s)
  Atsuko, Kimura, Ryuichi, Sakai, Kazufumui, Yoshida, Kanae, Koike, Atsushi, Kobiyama, Mitsuru, Jimbo, Hisao, Kamiya
- Organizer
  The Japanese Society of Fisheries Sciences, 2007 annual meeting
- Place of Presentation
  Tokyo, University of Marine Science and Technology
- Year and Date
  2007-04-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] A study toward identification of dysiherbaine-producing organism2007
- Author(s)
  Ryuichi, Sakai
- Organizer
  10th Marine Biotechnology Conference
- Place of Presentation
  Yamagata University
- Year and Date
  2007-05-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Chemical Biology of Neuroactive Spone Metabolites2007
- Author(s)
  Sakai, R., Matsunaga, S., Kimura, A., Koike, K., Koike, K., Jimbo, M., Kamiya, H
- Organizer
  VI^<th> US-Japan Seminar : Frontiers in Marine Natural Products Research
- Place of Presentation
  Park City Utah, U. S. A
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] 興奮性アミノ酸ダイシハーベインが局在する細胞の同定2007
- Author(s)
  木村敦子, 酒井隆一, 吉田和史, 小池一彦, 小池香苗, 小檜山篤志, 神保充, 神谷久男
- Organizer
  平成19年度日本水産学会春季大会
- Place of Presentation
  東京海洋大学
- Year and Date
  2007-04-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Chemical Biology of Neuroactive Sponge Metabolites,2007
- Author(s)
  Sakai R, Matsunaga S, Kimura A, Koike K, Koike K, Jimbo M, Kamiya H.
- Organizer
  VI^<th> US-Japan Seminar:Frontiers in Marine Natural Products Research.
- Place of Presentation
  Park City,Utah,U.S.A.
- Year and Date
  2007-07-04
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] 12007
- Author(s)
  酒井隆一
- Organizer
  マリンバイオテクノロジー学会
- Place of Presentation
  山形大学
- Year and Date
  2007-05-27
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] 海綿Axinyssa aculeataより得られた新規長鎖ポリアミンの骨片形成への関与2007
- Author(s)
  酒井隆一, 松永智子, 神保充, 神谷久男
- Organizer
  平成19年度日本水産学会春季大会
- Place of Presentation
  東京海洋大学
- Year and Date
  2007-04-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Isolation of novel neurotoxic peptide from the Marine sponge Axinyssa aculeata2007
- Author(s)
  Satoko, Matsunaga, Ryuichi, Sakai, Mitsuru, Jimbo, Hisao, Kamiya
- Organizer
  The Japanese Society of Fisheries Sciences, 2007 annual meeting
- Place of Presentation
  Tokyo University of Marine Science and Technology
- Year and Date
  2007-04-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] 興奮性アミノ酸ダイシハーベインの産生生物に関する研究2007
- Author(s)
  酒井隆一
- Organizer
  マリンバイオテクノロジー学会
- Place of Presentation
  山形大学
- Year and Date
  2007-05-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] 海綿Axinyssa aculeataより得られた新規神経ペプチドの分離と制製2007
- Author(s)
  松永智子, 酒井隆一, 神保充, 神谷久男
- Organizer
  平成19年度日本水産学会春季大会
- Place of Presentation
  東京海洋大学
- Year and Date
  2007-04-01
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] 海綿Axinyssa aculeataより得られた新規長鎖ポリアミンの構造とその機能2006
- Author(s)
  松永智子, 酒井隆一, 神保充, 神谷久男
- Organizer
  平成18年度日本水産学会大会
- Place of Presentation
  高知大学
- Year and Date
  2006-04-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Isolation of and structure determination of novel polyamines from the Marine sponge Axinyssa aculeata2006
- Author(s)
  Ryuichi, Sakai, Satoko, Matsunaga, Mitsuru, Jimbo, Hisao, Kamiya
- Organizer
  The Japanese Society of Fisheries Sciences, 2006 annual meeting
- Place of Presentation
  Kochi University
- Year and Date
  2006-04-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Isolation of novel polyamines from the Marine sponge Axinyssa aculeata : possible role in sponge spicule formation2006
- Author(s)
  Satoko, Matsunaga, Ryuichi, Sakai, Mitsuru, Jimbo, Hisao, Kamiya
- Organizer
  48th Symposium on the chemistry of Natural Products
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Long-chain polyamines from marine sponge:Implication in the silicon biomineralization in sponges2006
- Author(s)
  Satoko Matsunaga, Ryuichi Sakai, Mitsuru Jimbo, and Hisao Kamiya
- Organizer
  ICOB-5&ISCNP-25 IUPAC International conference on biodiversity and natural products
- Place of Presentation
  京都
- Year and Date
  2006-07-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] 海綿Axinyssa aculeataより得られた新規長鎖ポリアミンの骨片形成への関与2006
- Author(s)
  松永智子、酒井隆一、神保充、神谷久男
- Organizer
  第48回天然有機化合物討論会
- Place of Presentation
  仙台
- Year and Date
  2006-10-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Long-chain polyamines from marine sponge : Implication in the silicon biomineralization in sponges
- Author(s)
  Satoko, Matsunaga, Ryuichi, Sakai, Mitsuru, Jimbo, Hisao, Kamiya
- Organizer
  ICOB-5&ISCNP-25 IUPAC International conference on biodiversity and natural products
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380125
[Presentation] Novel Neuroactive Compounds From Aqueous Extracts of Marine Sponges.
- Author(s)
  Sakai R
- Organizer
  American Chemical Society Meeting
- Place of Presentation
  ペンシルバニア　コンベンションセンター　Philadelphia（USA)
- Invited
- Data Source
  KAKENHI-PROJECT-22380114

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Sakai Ryuichi 酒井 隆一

SAKAI Ryuichi 酒井 隆一

酒井 隆一 サカイ リュウイチ

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Exploring Marine Natural Products that Regulate Dynamic Responses of cellsPrincipal Investigator

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マルチオミクス解析で紐解くホヤのケミカルコミュニケーション戦略Principal Investigator

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Marine natural products that capture biological brriersPrincipal Investigator

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Marine polycations and their roles in chemical communicationPrincipal Investigator

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A direct structure determination using lectin-carbohydrate complexPrincipal Investigator

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Search for marine natural products that act on "cellular machinery" on cell surfacePrincipal Investigator

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Sakai Ryuichi 酒井隆一

SAKAI Ryuichi 酒井隆一

酒井隆一サカイリュウイチ