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Tohda Chihiro  東田 千尋

… Alternative Names

TOHDA Chihiro  東田 千尋

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Researcher Number 10272931
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-5738-4258
External Links
Affiliation (Current) 2022: 富山大学, 学術研究部薬学・和漢系, 教授
Affiliation (based on the past Project Information) *help 2019 – 2022: 富山大学, 学術研究部薬学・和漢系, 教授
2016 – 2018: 富山大学, 和漢医薬学総合研究所, 教授
2010 – 2016: 富山大学, 和漢医薬学総合研究所, 准教授
2012: 富山大学, 和漢医薬総合研究所, 准教授
2007 – 2009: University of Toyama, Inst. of Natl. Med, Assistant Professor … More
2007: University of Toyama, Institute of Natural Medicine, Associate Professor
2005 – 2007: 富山大学, 和漢医薬学総合研究所, 助手
1997 – 2004: 富山医科薬科大学, 和漢薬研究所, 助手 Less
Review Section/Research Field
Principal Investigator
Neurochemistry/Neuropharmacology / Biological pharmacy / Neurochemistry/Neuropharmacology / Natural medicines / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Basic Section 47050:Environmental and natural pharmaceutical resources-related
Except Principal Investigator
General internal medicine (including Psychosomatic medicine) / Environmental pharmacy / Chemical pharmacy … More / Environmental pharmacy / Psychiatric science / 応用薬理学・医療系薬学 / Aquatic life science / Natural medicines / General internal medicine(including psychosomatic medicine) / Basic Section 51030:Pathophysiologic neuroscience-related / Medium-sized Section 37:Biomolecular chemistry and related fields Less
Keywords
Principal Investigator
脊髄損傷 / 軸索修復 / 樹状突起 / 神経回路網 / 骨格筋萎縮 / Withanoside IV / RET / ACK1 / ニクジュヨウ / 頚椎症性脊髄症 … More / 痒み / NCマウス / substance P / MEF2C / アトピー性皮膚炎 / 和漢薬 / Differential Display / 大脳皮質 / RT-PCR / アンチセンスオリゴマー / sproutin / 脳スライス培養 / 初代培養神経細胞 / GFP / antisense oligomer / Sproutin / 神経ネットワーク / MAP2 / transfection / 免疫染色 / 軸索終末 / 軸索輸送 / mRNA / Axomer / 軸索伸展 / アストロサイト / vimentin / IGF1受容体 / DARTS法 / デノソミン / Vimentin / Western blotting / 国際情報交換 / 運動ニューロン / 生薬 / マイクログリア / 骨格筋細胞 / 軸索 / 皮質脊髄路 / 介在ニューロン / sominone / 記憶改善 / withanolide類 / シナプス形成 / 末梢性ミエリン / axon / neuregulin-I / estrogen receptor / PI3 kinase / 抗痴呆 / 中枢神経損傷 / neuron / myelin / Sominone / Memory improvement / Dendrite / Neuronal network / Spinal cord injury / 脊髄損傷慢性期 / acteoside / PKM2 / ロコモティブシンドローム / Acteoside / 生薬医薬品 / 筋萎縮 / 筋委縮 / ニクジュウヨウ / 精髄損傷 / myokine / 植物性医薬品 / アクテオシド … More
Except Principal Investigator
痴呆 / 分子系統学 / 品質評価 / 認知症 / dementia / アルツハイマー病 / 和漢薬 / BNIP-3 / 薬用植物 / 国際研究者交流 / molecular systematics / quality evaluation / 石菖蒲 / 軸索 / 漢方薬 / 東洋医学 / アルカロイド / 遺伝子発現 / 補中益気湯 / うつ病 / 刺五加 / 芍薬 / 国際協力 / 薬用植物学 / セロトニン / Panax / Curcuma / Rheum / HIV / 漢薬 / C型肝炎ウイルス / Chinese crude drug / hepatitis C virus / international exchange of researcher / M-CSF / 漢方 / 神経回路網 / シナプス / アルツハイマー / 黄耆 / Astragaloside IV / Astragalosides / 水迷路 / 伝統薬物 / 代替医療 / ハンチントン病 / アルッハイマー病 / 前頭葉 / 思春期 / MK-801 / prepulse inhibition / 統合失調症 / 統合薬理学 / MRI / 病態モデル / 機能性精神疾患 / 3D-HPLC / テーラーメード医療 / 薬物感受性 / 病態モデル動物 / ヒトによる実験 / 中枢神経 / 消化器系 / 上行性神経 / 脳基底部 / 初代培養細胞 / セロトニン2C受容体 / 学習性無気力動物 / ツメガエル卵母細胞 / 十全大補湯 / STAT3 / 生活習慣病 / 中国 / ベンゾジアゼピン / ジアザベンゾトロポン / AMPAレセプター / 神経性疾患 / 電子環状反応 / アポトーシス誘導 / 抗癌活性 / アミノ化 / 脱窒素反応 / 細胞毒性 / ベンゾトロポン / Gentiana属生薬 / アレルギー疾患 / エゾウコギ / 抗アレルギー / 抗炎症 / 秦ギョウ / 大黄 / 龍胆 / 党参 / NC系マウス / アレルギー性痒み / 掻き動作 / 一次求心線維 / 一酸化窒素 / ケラチノサイト / オピオイド拮抗薬 / 白虎加人参湯 / 痒み / アレルギー / ヒスタミン / テルフェナジン / NCマウス / 誘導型一酸化窒素合成酵素 / 蚊刺 / ロイコトリエンB4 / 免疫グロブリンE / NC mouse / Allergic itch / Scratching / Primary afferent / Nitric oxide / Keratinocyte / Opioid antagonist / Byakko-ka-ninjin-to / 民族薬物 / 品質 / ethno-medicines / 薬用資源 / モンゴル:中国:タイ / 地方 / エスロトジェン / HlV / medicinal resources / Mongolia : China : Thailand / 釣藤散 / 当帰芍薬散 / 和漢処方 / 記憶学習 / 両方向性調節 / 遺伝子発現変化 / C6グリオーマ / 抗うつ / ウイリアムズ症候群 / CSF / NG108-15 / Wakan-yaku / Chotosan / depressive disorder / Hochuekkito / mRNA expression / 中国:モンゴル:タイ / 抗炎症作用 / 中国:モンゴル:タ / medicinal plants / China : Mongolia : Thailand / 海綿 / ホヤ / 神経受容体 / 毒素 / タンパク質 / ペプチド / 海洋天然物 / シナプス受容体 / グアニジンアルカロイド / トロンボポエチン / ペプチド毒 / サイトカイン / ドラッグデリバリ / ポリアミン / 膜透過 / 分子送達 / 糖鎖 / ビオプテリン / グルタミン酸受容体 / 生理活性 / 細胞内送達 / ドラッグデリバリー / 神経修復 / 生理活性物質 / 海洋生物 / 生理活性タンパク質 / 細胞膜 / 薬用資源学 / 生物活性 / がん / 防風 / 骨砕補 / 車前子 / 癌 / 山椒 / ハイブリッド化 / 天然物 / 神経賦活作用 / カップリング反応 / ハブリッド化 / デノソミン / ドラッグ・リポジショニング / 複雑系 / 医薬ビッグデータ / 機械学習 / in silico結合シミュレーション / インシリコ / 機械学習手法 / 結合シミュレーション / 標的タンパク質探索 / 実験薬理学的検証 / 和漢医薬学 / リポジショニング / 標的タンパク質 / マイクログリア / HDAC3 / アミロイドβ / 軸索変性 / 記憶障害 / M2 / M2マイクログリア / 記憶改善 / ユビキチン / プロテアソーム Less

  • Research Projects

    (26 results)

  • Research Products

    (609 results)

  • Co-Researchers

    (60 People)

  •  頚椎症性脊髄症の機能を軸索修復により根本的に回復する新しい植物性医薬品の開発Principal Investigator

    • Principal Investigator
      東田 千尋
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      University of Toyama

  •  Development of anti-Alzheimer's disease based on a ubiquitin-proteasome activator

    • Principal Investigator
      KAIDA Daisuke
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 37:Biomolecular chemistry and related fields
    • Research Institution
      University of Toyama

  •  Development of therapeutic strategy for Alzheimer's disease via M2 microglia

    • Principal Investigator
      Kuboyama Tomoharu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Daiichi University, College of Pharmaceutical Sciences
      University of Toyama

  •  Drug therapy of chronic phase of spinal cord injury; development of botanical drugs to improve muscle atrophy and axonal disruptionPrincipal Investigator

    • Principal Investigator
      Tohda Chihiro
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      University of Toyama

  •  Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseases

    • Principal Investigator
      Kadowaki Makoto
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      University of Toyama

  •  Search for marine natural products that act on "cellular machinery" on cell surface

    • Principal Investigator
      Sakai Ryuichi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Aquatic life science
    • Research Institution
      Hokkaido University

  •  Study on medicinal plants in Asia for sustainable use of traditional medicines

    • Principal Investigator
      KOMATSU Katsuko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Natural medicines
    • Research Institution
      University of Toyama

  •  Traditional medicine-based drug development-creation of new paradigm-Principal Investigator

    • Principal Investigator
      Tohda Chihiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Natural medicines
    • Research Institution
      University of Toyama

  •  Design, Synthesis, and Structure-Activity Relationship Study of Novel Neuro-Protecting Drugs Based on Natural Product Hybridization

    • Principal Investigator
      Matsuya Yuji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      University of Toyama

  •  Construction of a program for sustainable use of traditional medicines, based on integrated study of genetic, chemical and pharmacological diversity of medicinal plants

    • Principal Investigator
      KOMATSU Katsuko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      University of Toyama

  •  Recovery from spinal cord injury in the chronic phase -the mechanism of denosomin, a novel compound with multiactivities-Principal Investigator

    • Principal Investigator
      TOHDA Chihiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      University of Toyama

  •  Studies for the detail mechanisms of depression onset and the development of novel antidepressants based on "the Wakan-yaku, Sino-Japanese traditional medicine, theory"

    • Principal Investigator
      TOHDA Michihisa
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama

  •  Analysis on genetic, chemical and pharmacological diversity of medicinal plants, towards sustainable uses of traditional medicines

    • Principal Investigator
      KOMATSU Katsuko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      University of Toyama

  •  Development of Novel Methodology for the Synthesis of 2, 3-Benzodiazepines and Application for Neuro-therapeutic Agents

    • Principal Investigator
      MATSUYA Yuji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      University of Toyama

  •  Frontal lobe pathology in schizophrenia : its pathogenesis and the development of the drug

    • Principal Investigator
      KURACHI Masayoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      University of Toyama

  •  神経変性疾患に有効な伝統薬物分子の探索とその治療戦略

    • Principal Investigator
      小松 かつ子
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama

  •  漢方処方を進化させる科学的アプローチ-痴呆を治療する処方の開発-

    • Principal Investigator
      KOMATSU Katsuko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama

  •  Identification of the intrinsic molecules which are involved in the generation of disease, and the analysis of the molecular mechanisms and functions, by using Wakan-yaku, Japanese traditional systematized medicine

    • Principal Investigator
      TOHDA Michihisa
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      University of Toyama

  •  Investigation on Kampo Drug Resources in Asia and Analysis on Diversity ofMedicinal Plants

    • Principal Investigator
      KOMATSU Katsuko
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      University of Toyama

  •  Study of the molecular mechanism of synaptogenesis using withanolides, novel anti-dementia drugsPrincipal Investigator

    • Principal Investigator
      TOHDA Chihiro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      University of Toyama

  •  Inquiry into Kampo Drug Resources of Asia : Investigation on Mongolian and Thai Medicinal Plants

    • Principal Investigator
      KOMATSU Katsuko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY

  •  神経軸索終末に輸送されるmRNAのクローニング〜軸索形成に関与する因子の解析〜Principal Investigator

    • Principal Investigator
      東田 千尋
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Toyama Medical and Pharmaceutical University

  •  新規因子sproutinの神経ネットワーク賦活化と痴呆の改善に及ぼす作用Principal Investigator

    • Principal Investigator
      東田 千尋
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Toyama Medical and Pharmaceutical University

  •  Comparative Ethnopharmacology in China

    • Principal Investigator
      KOMATSU Katsuko
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Toyama Medical and Pharmaceutical University

  •  MECHANISMS OF ALLERGIC ITCH

    • Principal Investigator
      KURAISHI Yasushi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY

  •  アトピー性皮膚炎の痒みに関連した因子の単離、同定および機能解析Principal Investigator

    • Principal Investigator
      東田 千尋
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Toyama Medical and Pharmaceutical University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] 認知症に有効な漢方薬・生薬．漢方薬・生薬薬剤師講座テキスト第5版2021
    • Author(s)
      東田千尋
    • Total Pages
      12
    • Publisher
      財団法人　日本薬剤師研修センター
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Book] ファーマシューティカルノート:第2版2008
    • Author(s)
      東田道久
    • Total Pages
      629
    • Publisher
      医学評論社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Book] 「ファーマシューティカルノート:第2版」(百瀬弥寿徳 編)2008
    • Author(s)
      東田 道久
    • Total Pages
      629
    • Publisher
      医学評論社
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Book] ファーマコセラピー2007
    • Author(s)
      東田道久(訳)
    • Total Pages
      3562
    • Publisher
      ブレーン出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Book] コーヒーの科学と機能2006
    • Author(s)
      東田千尋, 小松かつ子, 中村憲夫, 服部征雄
    • Total Pages
      214
    • Publisher
      アイ・ケイコーポレーション
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Book] 民族薬物の謎を追って, 佐竹元吉監修『薬用植物・生薬の開発』2006
    • Author(s)
      小松かつ子, 東田千尋
    • Publisher
      シーエムシー
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Book] 民族薬物の謎を追って『薬用植物・生薬の開発』(佐竹元吉監修)2006
    • Author(s)
      小松かつ子, 東田千尋
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Book] 認知症に対するコーヒーの作用, 『コーヒーの科学と機能』2006
    • Author(s)
      東田千尋, 小松かつ子, 中村憲夫, 服部征雄
    • Publisher
      アイ・ケイコーポレーション
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Book] 民族薬物の謎:世界の人参を追って-多様性の解析と認知症治療薬としての可能性-, 佐竹元吉監修『薬用植物・生薬開発の新展開』2005
    • Author(s)
      小松かつ子, 東田千尋
    • Publisher
      シーエムシー
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Book] 薬用植物・生薬開発の新展開 New Development of Medical Plant2005
    • Author(s)
      小松かつ子, 東田千尋
    • Total Pages
      337
    • Publisher
      シーエムシー
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Book] 第21章 民族薬物の謎:世界の人参を追って-多様性の解析と認知症治療薬としての可能性-,佐竹元吉監修『薬用植物・生薬開発の新展開』2005
    • Author(s)
      小松かつ子, 東田千尋
    • Publisher
      シーエムシー
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Effects of <i>Trigonella foenum-graecum</i> seeds extract on Alzheimer’s disease transgenic model mouse and its potential active compound transferred to the brain2021
    • Author(s)
      Mai M. Farid、長瀬 綸沙、楊 熙蒙、野本 かおり、久保山 友晴、稲田 祐奈、東田 千尋
    • Journal Title

      Japanese Journal of Food Chemistry and Safety

      Volume: 28 Issue: 2 Pages: 63-70

    • DOI

      10.18891/jjfcs.28.2_63

    • NAID

      130008080445

    • ISSN
      1341-2094, 2189-6445
    • Language
      English
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Intrathecal Infusion of Diosgenin during the Chronic Phase of Spinal Cord Injury Ameliorates Motor Function and Axonal Density2021
    • Author(s)
      Nakano Aoi、Yang Ximeng、Kuboyama Tomoharu、Inada Yuna、Tohda Chihiro
    • Journal Title

      Neurochemical Journal

      Volume: 15 Pages: 454-461

    • DOI

      10.1134/s1819712421040085

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] A Novel Heptapeptide, GPPGPAG Transfers to the Brain, and Ameliorates Memory Dysfunction and Dendritic Atrophy in Alzheimer’s Disease Model Mice2021
    • Author(s)
      Tohda Chihiro、Kogure Chisato、Nomoto Kaori、Toledo Andreia de、Yang Ximeng、Hirano Eiichi
    • Journal Title

      Frontiers in Pharmacology

      Volume: 12 Pages: 680652-680652

    • DOI

      10.3389/fphar.2021.680652

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Recovery from spinal cord injury via M2 microglial polarization induced by Polygalae Radix2021
    • Author(s)
      Kuboyama Tomoharu、Kominato Seiya、Nagumo Misaki、Tohda Chihiro
    • Journal Title

      Phytomedicine

      Volume: 82 Pages: 153452-153452

    • DOI

      10.1016/j.phymed.2020.153452

    • NAID

      130008001435

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558, KAKENHI-PROJECT-18K07389

  • [Journal Article] Skeletal muscle atrophy‐induced hemopexin accelerates onset of cognitive impairment in Alzheimer's disease2021
    • Author(s)
      Nagase Tsukasa、Tohda Chihiro
    • Journal Title

      Journal of Cachexia, Sarcopenia and Muscle

      Volume: 12 Pages: 2199-2210

    • DOI

      10.1002/jcsm.12830

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Effects of Cistanche tubulosa Wight Extract on Locomotive Syndrome: A Placebo-Controlled, Randomized, Double-Blind Study2021
    • Author(s)
      Inada Yuna、Tohda Chihiro、Yang Ximeng
    • Journal Title

      Nutrients

      Volume: 13 Pages: 264-264

    • DOI

      10.3390/nu13010264

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] ジオスゲニンの認知機能改善効果．2021
    • Author(s)
      東田 千尋、楊 熙蒙、稲田 祐奈．
    • Journal Title

      Functional Food(2021) 40号

      Volume: 15(1) Pages: 10-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Horse Placental Extract Enhances Neurogenesis in the Presence of Amyloid β2021
    • Author(s)
      de Toledo Andreia、Nomoto Kaori、Hirano Eiichi、Tohda Chihiro
    • Journal Title

      Nutrients

      Volume: 13 Pages: 1672-1672

    • DOI

      10.3390/nu13051672

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Combined Treatment with Two Water Extracts of Eleutherococcus senticosus Leaf and Rhizome of Drynaria fortunei Enhances Cognitive Function: A Placebo-Controlled, Randomized, Double-Blind Study in Healthy Adults2020
    • Author(s)
      Tohda Chihiro、Matsui Mie、Inada Yuna、Yang Ximeng、Kuboyama Tomoharu、Kimbara Yoshiyuki、Watari Hidetoshi
    • Journal Title

      Nutrients

      Volume: 12 Pages: 303-303

    • DOI

      10.3390/nu12020303

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] ジオスゲニンによる認知機能の向上2020
    • Author(s)
      東田千尋
    • Journal Title

      Food STYLE 21

      Volume: 24(2) Pages: 34-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Natural Medicines and Their Underlying Mechanisms of Prevention and Recovery from Amyloid Β-Induced Axonal Degeneration in Alzheimer’s Disease2020
    • Author(s)
      Kuboyama Tomoharu、Yang Ximeng、Tohda Chihiro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Pages: 4665-4665

    • DOI

      10.3390/ijms21134665

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558, KAKENHI-PROJECT-18K07389

  • [Journal Article] Transported amount of diosgenin to the brain is differed by a solvent fat.2020
    • Author(s)
      Tohda C, Yang X, Nomoto K.
    • Journal Title

      日本食品化学学会誌 Japanese Journal of Food Chemistry and Safety

      Volume: 27(2) Pages: 102-105

    • NAID

      130007893451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Trigonelline recovers memory function in Alzheimer’s disease model mice: evidence of brain penetration and target molecule2020
    • Author(s)
      Farid Mai M.、Yang Ximeng、Kuboyama Tomoharu、Tohda Chihiro
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 16424-16424

    • DOI

      10.1038/s41598-020-73514-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] GRP78-Mediated Signaling Contributes to Axonal Growth Resulting in Motor Function Recovery in Spinal Cord-Injured Mice2020
    • Author(s)
      Tanie Yoshitaka、Kuboyama Tomoharu、Tohda Chihiro
    • Journal Title

      Frontiers in Pharmacology

      Volume: 11 Pages: 789-789

    • DOI

      10.3389/fphar.2020.00789

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Diosgenin content is a novel criterion to assess memory enhancement effect of yam extracts2020
    • Author(s)
      Yang Ximeng、Nomoto Kaori、Tohda Chihiro
    • Journal Title

      Journal of Natural Medicines

      Volume: 75 Pages: 207-216

    • DOI

      10.1007/s11418-020-01451-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] 認知機能を制御するファイトケミカル2020
    • Author(s)
      東田千尋、楊熙蒙
    • Journal Title

      医学のあゆみ

      Volume: 270(8) Pages: 605-609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Recovery of motor function of chronic spinal cord injury by extracellular pyruvate kinase isoform M2 and the underlying mechanism2020
    • Author(s)
      Kikuchi Takahiro、Tohda Chihiro、Suyama Masato
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 19475-19475

    • DOI

      10.1038/s41598-020-76629-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Matrine promotes neural circuit remodeling to regulate motor function in a mouse model of chronic spinal cord injury2019
    • Author(s)
      Tohda Chihiro、Tanabe Norio、Kuboyama Tomoharu
    • Journal Title

      Neural Regeneration Research

      Volume: 14 Pages: 1961-1961

    • DOI

      10.4103/1673-5374.259625

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Naringenin promotes microglial M2 polarization and Aβ degradation enzyme expression2019
    • Author(s)
      Yang Zhiyou、Kuboyama Tomoharu、Tohda Chihiro
    • Journal Title

      Phytotherapy Research

      Volume: in press Pages: 1114-1121

    • DOI

      10.1002/ptr.6305

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07389, KAKENHI-PROJECT-17H03558

  • [Journal Article] Cistanche tubulosa (Schenk) Wight Extract Enhances Hindlimb Performance and Attenuates Myosin Heavy Chain IId/IIx Expression in Cast-Immobilized Mice2019
    • Author(s)
      Kimbara Yoshiyuki、Shimada Yutaka、Kuboyama Tomoharu、Tohda Chihiro
    • Journal Title

      Evidence-Based Complementary and Alternative Medicine

      Volume: 2019 Pages: 1-10

    • DOI

      10.1155/2019/9283171

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Acteoside Improves Muscle Atrophy and Motor Function by Inducing New Myokine Secretion in Chronic Spinal Cord Injury2019
    • Author(s)
      Kodani A, Kikuchi T, Tohda C.
    • Journal Title

      Journal of Neurotrauma

      Volume: 35 Pages: 1-14

    • DOI

      10.1089/neu.2018.6000

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558

  • [Journal Article] Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain2019
    • Author(s)
      Yamauchi Yui、Ge Yue-Wei、Yoshimatsu Kayo、Komatsu Katsuko、Kuboyama Tomoharu、Yang Ximeng、Tohda Chihiro
    • Journal Title

      Nutrients

      Volume: 11 Pages: 1142-1142

    • DOI

      10.3390/nu11051142

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Matrine promotes neural circuit remodeling to regulate motor function in a chronic model of spinal cord injury.2019
    • Author(s)
      Tanabe Norio, Kuboyama Tomoharu, Tohda Chihiro.
    • Journal Title

      Neural Regeneration Research

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Porcine placental extract facilitates memory and learning in aged mice2019
    • Author(s)
      Yamauchi Akihiro、Tone Takahiro、Sugimoto Koji、Seok Lim Hong、Kaku Taiichi、Tohda Chihiro、Shindo Takayuki、Tamada Koji、Mizukami Yoichi、Hirano Eiichi
    • Journal Title

      Food Science & Nutrition

      Volume: 7 Pages: 2995-3005

    • DOI

      10.1002/fsn3.1156

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08572, KAKENHI-PROJECT-18K11128, KAKENHI-PROJECT-17H03558, KAKENHI-PROJECT-18H02602

  • [Journal Article] Kihito, a Traditional Japanese Kampo Medicine, Improves Cognitive Function in Alzheimer’s Disease Patients2019
    • Author(s)
      Watari Hidetoshi、Shimada Yutaka、Matsui Mie、Tohda Chihiro
    • Journal Title

      Evidence-Based Complementary and Alternative Medicine

      Volume: 2019 Pages: 1-7

    • DOI

      10.1155/2019/4086749

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Heat Shock Cognate 70 inhibitor, VER-155008, reduces memory deficits and axonal degeneration in a mouse model of Alzheimer’s disease.2018
    • Author(s)
      Yang X., Tohda C.
    • Journal Title

      Frontiers in Pharmacology

      Volume: 9 Pages: 48-48

    • DOI

      10.3389/fphar.2018.00048

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558

  • [Journal Article] Diosgenin restores Aβ-induced axonal degeneration by reducing the expression of heat shock cognate 70 (HSC70)2018
    • Author(s)
      Yang X, Tohda C.
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 11707-11707

    • DOI

      10.1038/s41598-018-30102-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558

  • [Journal Article] Extracellular Neuroleukin Enhances Neuroleukin Secretion From Astrocytes and Promotes Axonal Growth in vitro and in vivo.2018
    • Author(s)
      Tanie Y, Tanabe N, Kuboyama T, Tohda C.
    • Journal Title

      Front Pharmacol.

      Volume: 9 Pages: 1228-1228

    • DOI

      10.3389/fphar.2018.01228

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05276

  • [Journal Article] Matrine Directly Activates Extracellular Heat Shock Protein 90, Resulting in Axonal Growth and Functional Recovery in Spinal Cord Injured-Mice2018
    • Author(s)
      Tanabe N, Kuboyama T, Tohda C.
    • Journal Title

      Frontiers in Pharmacology

      Volume: 9 Pages: 446-446

    • DOI

      10.3389/fphar.2018.00446

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558

  • [Journal Article] Roles of Cdc42 and Rac in Bergmann glia during cerebellar corticogenesis2018
    • Author(s)
      Sakamoto I, Ueyama T, Hayashibe M, Nakamura T, Mohri H, Kiyonari H, Shigyo M, Tohda C, Saito N.
    • Journal Title

      Experimental Neurology

      Volume: 302 Pages: 57-67

    • DOI

      10.1016/j.expneurol.2017.12.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-17H04032

  • [Journal Article] 和漢薬創薬を目指した基礎研究と臨床研究．2018
    • Author(s)
      東田千尋、久保山友晴、楊熙蒙、
    • Journal Title

      生体の科学

      Volume: 69 Pages: 354-357

    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] Extracellular Cytosolic Aspartate Aminotransferase Promotes Axonal Growth and Object Recognition Memory.2017
    • Author(s)
      Kobayashi R., Tohda C.
    • Journal Title

      Neurochem Res.

      Volume: 42 Pages: 3465-3473

    • DOI

      10.1007/s11064-017-2394-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558

  • [Journal Article] Polygalae Radix extract prevents axonal degeneration and memory deficits in a transgenic mouse model of Alzheimer’s disease.2017
    • Author(s)
      Kuboyama T., Hirotsu K., Arai T., Yamasaki H., Tohda C.
    • Journal Title

      Frontiers in Pharmacology

      Volume: 8 Pages: 805-805

    • DOI

      10.3389/fphar.2017.00805

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558

  • [Journal Article] Extracellular cathepsin L stimulates axonal growth in neurons.2017
    • Author(s)
      Tohda C, Tohda M.
    • Journal Title

      BMC Research Note

      Volume: 10 Pages: 613-613

    • DOI

      10.1186/s13104-017-2940-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury.2017
    • Author(s)
      Ishii T, Ueyama T, Shigyo M, Kohta M, Kondoh T, Kuboyama T, Uebi T, Hamada T, Gutmann DH, Aiba A, Kohmura E, Tohda C, Saito N
    • Journal Title

      J. Biol. Chem.,

      Volume: 292 Pages: 1240-1250

    • DOI

      10.1074/jbc.m116.748871

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-17H03558, KAKENHI-PROJECT-17H04032

  • [Journal Article] A systematic strategy for discovering a therapeutic drug for Alzheimer’s disease and its target molecule.2017
    • Author(s)
      Yang Z., Kuboyama T., Tohda C.
    • Journal Title

      Front Pharmacol.

      Volume: 8 Pages: 340-340

    • DOI

      10.3389/fphar.2017.00340

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05268, KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558

  • [Journal Article] Diosgenin-Rich Yam Extract Enhances Cognitive Function: A Placebo-Controlled, Randomized, Double-Blind, Crossover Study of Healthy Adults.2017
    • Author(s)
      Tohda C., Yang X., Matsui M., Inada Y., Kadomoto E., Nakada S., Watari H., Shibahara N.
    • Journal Title

      Nutrients

      Volume: 9 Pages: 1160-1160

    • DOI

      10.3390/nu9101160

    • NAID

      120006375104

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-17H03558

  • [Journal Article] Human placenta extract ameliorates memory dysfunction and dendritic atrophy in a 5XFAD mouse model of Alzheimer’s disease.2017
    • Author(s)
      Kogure C, Tohda C.
    • Journal Title

      Traditional & Kampo Medicine

      Volume: 4(2) Pages: 94-104

    • DOI

      10.1002/tkm2.1075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Journal Article] The Extract of Roots of Sophora flavescens Enhances the Recovery of Motor Function by Axonal Growth in Mice with a Spinal Cord Injury.2016
    • Author(s)
      Tanabe N, Kuboyama T, Kazuma K, Konno K, Tohda C.
    • Journal Title

      Front Pharmacol.

      Volume: 6:326 Pages: 1-10

    • DOI

      10.3389/fphar.2015.00326

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670044, KAKENHI-PROJECT-16H05276

  • [Journal Article] Extracellular vimentin is a novel axonal growth facilitator for functional recovery in spinal cord-injured mice.2016
    • Author(s)
      Shigyo M, Tohda C.
    • Journal Title

      Sci Rep.

      Volume: 6 Pages: 28293-28293

    • DOI

      10.1038/srep28293

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044, KAKENHI-PROJECT-16H05276

  • [Journal Article] New Age Therapy for Alzheimer’s Disease by Neuronal Network Reconstruction2016
    • Author(s)
      Tohda C.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 39 Issue: 10 Pages: 1569-1575

    • DOI

      10.1248/bpb.b16-00438

    • NAID

      130005598483

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05268, KAKENHI-PROJECT-26670044, KAKENHI-PROJECT-16H05276

  • [Journal Article] Effects of Oleanane-type triterpene saponins from the leaves of Eleutherococcus senticosus in an axonal outgrowth assay.2016
    • Author(s)
      Ge Y. W., Tohda C., Zhu S., He Y. M., Yoshimatsu K., Komatsu K.
    • Journal Title

      J. Nat. Prod.

      Volume: 79 Pages: 1834-1841

    • DOI

      10.1021/acs.jnatprod.6b00329

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Journal Article] Cytosolic aspartate aminotransferase, a direct binding protein of kamikihito, regulates axon growth.2016
    • Author(s)
      Watari H, Shimada Y, Tohda C.
    • Journal Title

      Traditional Kampo Medicine

      Volume: Iss Pages: 1-9

    • DOI

      10.1002/tkm2.1037

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Journal Article] アルツハイマー病の記憶障害を改善する帰脾湯・加味帰脾湯．2015
    • Author(s)
      東田千尋、渡り英俊
    • Journal Title

      日本薬理学雑誌

      Volume: 145 Pages: 224-228

    • NAID

      130005067374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Journal Article] Comparing the effects of kamikihito in Japan and kami-guibi-tang in Korea on memory enhancement: working towards the development of a global study.2015
    • Author(s)
      Watari H, Shigyo M, Tanabe N, Tohda M, Cho KH, Kyung PS, Jung WS, Shimada Y, Shibahara N, Kuboyama T, Tohda C.
    • Journal Title

      Phytother Res.

      Volume: 29 Pages: 351-356

    • DOI

      10.1002/ptr.5250

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Journal Article] Synthesis of Denosomin&#8211;Vitamin D3 Hybrids and Evaluation of their Anti-Alzheimer's Disease Activities.2015
    • Author(s)
      Sugimoto K, Yajima H, Hayashi Y, Minato D, Terasaki S, Tohda C, Matsuya Y.
    • Journal Title

      Organic Letters

      Volume: 17(23) Pages: 5910-5913

    • DOI

      10.1021/acs.orglett.5b03138

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670044, KAKENHI-PROJECT-25460010

  • [Journal Article] Inhibition of clathrin-mediated endocytosis prevents amyloid β-induced axonal damage.2015
    • Author(s)
      Kuboyama T, Lee YA, Nishiko H, Tohda C.
    • Journal Title

      Neurobiol Aging

      Volume: ?

    • DOI

      10.1016/j.neurobiolaging.2015.02.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Journal Article] Active constituents from Drynaria fortunei Rhizomes on the attenuation of Aβ25-35-induced axonal atrophy2015
    • Author(s)
      Yang Z, Kuboyama T, Kazuma K, Konno K, Tohda C.
    • Journal Title

      J. Nat. Prod.

      Volume: 78(9) Pages: 2297-2300

    • DOI

      10.1021/acs.jnatprod.5b00290

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670044, KAKENHI-PROJECT-15H05268

  • [Journal Article] Extracellular vimentin interacts with insulin-like growth factor 1 receptor to promote axonal growth.2015
    • Author(s)
      Shigyo M, Kuboyama T, Sawai Y, Tada-Umezaki M, Tohda C.
    • Journal Title

      Scientific Reports

      Volume: 5:12055. Pages: 1-13

    • DOI

      10.1038/srep12055

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Journal Article] New reliable scoring system, Toyama mouse score, to evaluate locomotor function following spinal cord injury in mice.2014
    • Author(s)
      Shigyo M, Tanabe N, Kuboyama T, Choi SH, Tohda C.
    • Journal Title

      BMC Res Notes

      Volume: 7 Pages: 332-332

    • DOI

      10.1186/1756-0500-7-332

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Journal Article] Synthesis of long-chain fatty acid derivatives as a novel anti-Alzheimer's agent2014
    • Author(s)
      Zhang H-Y, Yamakawa Y , Matsuya Y , Toyooka N, Tohda C, Awale S, Li F, Kadota S, Tezuka Y
    • Journal Title

      Bioorg Med Chem Lett.

      Volume: 24(2) Pages: 604-608

    • DOI

      10.1016/j.bmcl.2013.12.008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23500439, KAKENHI-PROJECT-26670044

  • [Journal Article] Effects of Ashwagandha (roots of Withania somnifera Dunal) on neurodegenerative diseases2014
    • Author(s)
      Kuboyama T, Tohda C, Komatsu K
    • Journal Title

      Biol Pharm Bull

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of　Alzheimer's disease.2014
    • Author(s)
      Thiratmatrakul S, Yenjai C, Waiwut P, Vajragupta O, Reubroycharoen P, Tohda M, and Boonyarat C.
    • Journal Title

      European Journal of Medicinal Chemistry

      Volume: 75 Pages: 21-30

    • DOI

      10.1016/j.ejmech.2014.01.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] New treatment for Alzheimer's disease, kamikihito, reverses amyloid-β-induced progression of tau phosphorylation and axonal atrophy2014
    • Author(s)
      Watari H, Shimada Y, Tohda C
    • Journal Title

      Evidence-Based Complementary and Alternative Medicine

      Volume: 2014 Article ID 706487 Pages: 1-10

    • DOI

      10.1155/2014/706487

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23500439, KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-26670044

  • [Journal Article] 伝統薬物研究が薬理学にもたらす新しい視点2014
    • Author(s)
      東田千尋, 久保山友晴
    • Journal Title

      日本薬理学雑誌

      Volume: 143 Pages: 73-77

    • NAID

      130003391427

    • URL

      http://plaza.umin.ac.jp/JPS1927/fpj/issue/TOC14-143(2)/14-143-2.htm

    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Changes in the expression of BNIP-3 and other neuronal factors during the cultivation period of primary cultured rat cerebral cortical neurons and an assessment of each factor’s functions.2014
    • Author(s)
      Tohda M
    • Journal Title

      Cell Signal Traffic.

      Volume: 2014; 2:1 Pages: 1-8

    • DOI

      10.7243/2054-1481-2-1

    • URL

      http://www.hoajonline.com/journals/pdf/2054-1481-2-1.pdf

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] Effects of Ashwagandha (roots of Withania somnifera Dunal) on neurodegenerative diseases.2014
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      Biol Pharm Bull

      Volume: 37(6)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] 薬用植物の多彩な作用点を明らかにする―新しい薬効機序発見への糸口―．2014
    • Author(s)
      東田千尋
    • Journal Title

      実験医学

      Volume: 32(3) Pages: 416-417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] 伝統薬物研究が薬理学にもたらす新しい視点．2014
    • Author(s)
      東田千尋、久保山友晴、
    • Journal Title

      日本薬理学雑誌

      Volume: 143 Pages: 73-77

    • NAID

      130003391427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Journal Article] 薬用植物の多彩な作用点を明らかにする―新しい薬効機序発見への糸口―．2014
    • Author(s)
      東田千尋
    • Journal Title

      実験医学

      Volume: 32 Pages: 416-417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Journal Article] Effects of Ashwagandha (roots of Withania somnifera Dunal) on neurodegenerative diseases.2014
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      Biol Pharm Bull

      Volume: 37 Pages: 892-897

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Journal Article] 薬用植物の多彩な作用点を明らかにする-新しい薬効機序発見への糸口-2014
    • Author(s)
      東田千尋
    • Journal Title

      実験医学

      Volume: 32(3) Pages: 416-417

    • URL

      https://www.yodosha.co.jp/jikkenigaku/nhpd/9784758101240/c1.html

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] 伝統薬物研究が薬理学にもたらす新しい視点．2014
    • Author(s)
      東田千尋、久保山友晴
    • Journal Title

      日本薬理学雑誌

      Volume: 143 Pages: 73-77

    • NAID

      130003391427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Effects of Ashwagandha (roots of Withania somnifera) on neurodegenerative diseases2014
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 37

    • NAID

      130004147346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Journal Article] A novel compound, Denosomin ameliorates spinal cord injury via axonal growth associated with astrocyte-secreted vimentin.2013
    • Author(s)
      Teshigawara K, Kuboyama T, Shigyo M, Nagata A, Sugimoto K, Matsuya Y, Tohda C.
    • Journal Title

      Br J Pharmacol

      Volume: 168 Pages: 903-919

    • DOI

      10.1111/j.1476-5381.2012.02211.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790246, KAKENHI-PROJECT-23500439, KAKENHI-PROJECT-23700376, KAKENHI-PROJECT-24406005

  • [Journal Article] Evidence of Antidepressive Effects of a Wakan-yaku, Hochuekkito, in Depression Model Mice with Learned-Helplessness Behavior.2013
    • Author(s)
      Tohda M. and Mingmalairak S
    • Journal Title

      Evid Based Complement Alternat Med.

      Volume: vol. 2013 Pages: 319073-319073

    • DOI

      10.1155/2013/319073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] Diosgenin-induced cognitive enhancement in normal mice is mediated by 1, 25D_3-MARRS2013
    • Author(s)
      Tohda C, Lee Y-A, Goto Y, Nemere I
    • Journal Title

      Scientific Reports

      Volume: 3 Pages: 3395-3395

    • DOI

      10.1038/srep03395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439, KAKENHI-PROJECT-24406005

  • [Journal Article] Paxillin phosphorylation counteracts proteoglycan-mediated inhibition of axon regeneration.2013
    • Author(s)
      Tomoharu Kuboyama, Xueting Luo, Kevin Park, Murray G. Blackmore, Takuro Tojima, Chihiro Tohda, John L. Bixby, Vance P. Lemmon, Hiroyuki Kamiguchi
    • Journal Title

      Exp Neurol

      Volume: 248 Pages: 157-169

    • DOI

      10.1016/j.expneurol.2013.06.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23110005, KAKENHI-PROJECT-23500439, KAKENHI-PROJECT-23700376, KAKENHI-PROJECT-24300137, KAKENHI-PROJECT-24500393

  • [Journal Article] Structure-activity-relationship studies on dihydrofuran-fused perhydrophenanthrenes as an anti-Alzheimer's disease agent2013
    • Author(s)
      Sugimoto K, Tamura K, Tohda C, Toyooka N, Nemoto H, Matsuya Y.
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 21 Pages: 4459-4471

    • DOI

      10.1016/j.bmc.2013.05.059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Diosgenin is an exogenous activator of 1, 25D_3-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice2012
    • Author(s)
      Tohda C, Urano T, Umezaki M, Nemere I, Kuboyama T.
    • Journal Title

      Sci Rep

      Volume: 2 Pages: 535-535

    • DOI

      10.1038/srep00535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439, KAKENHI-PROJECT-23700376, KAKENHI-PROJECT-24406005

  • [Journal Article] Synthesis of dihydrofuran-fused perhydrophenanthrenes having a phenolic hydroxyl group as a novel anti-Alzheimer's disease agent2012
    • Author(s)
      Sugimoto K, Tamura K, Ohta N, Tohda C, Toyooka N, Nemoto H, Matsuya Y
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 22(1) Pages: 449-452

    • DOI

      10.1016/j.bmcl.2011.10.127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Screening of fractions from some Chinese herbs for spinal cord injury.2012
    • Author(s)
      Wang X-H, Zhu H, Konno K, Tohda C, Kazuma K, Kuboyama T, Miyanaga S.
    • Journal Title

      Chinese Journal of Experimental Traditional Medical Formulae

      Volume: 18 Pages: 246-248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Clarification of generating mechanisms of various types of depression based on the Wakan-yaku theory for development of novel antidepressants.2012
    • Author(s)
      Tohda, M
    • Journal Title

      J. Trad. Med.

      Volume: 29 Pages: 85-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] Epimedium koreanum extract and its constituent icariin improve motor dysfunction in spinal cord injury2012
    • Author(s)
      Tohda C, Nagata A.
    • Journal Title

      Evid. Based Complement. Alternat. Med.

      Volume: 2012 Pages: 731208-731208

    • DOI

      10.1155/2012/731208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439, KAKENHI-PROJECT-24406005

  • [Journal Article] Screening of fractions from some Chinese herbs for spinal cord injury2012
    • Author(s)
      Wang X-H, Zhu H, Konno K, Tohda C, Kazuma K, Kuboyama T, Miyanaga S
    • Journal Title

      Chinese Journal of Experimental Traditional Medical Formulae

      Volume: 18(12) Pages: 246-248

    • URL

      http://en.cnki.com.cn/Article_en/CJFDTotal-ZSFX201212072.htm

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Synthesis of dihydrofuran-fused2012
    • Author(s)
      Sugimoto K, Tamura K, Ohta N, Tohda C, et al
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 22 Pages: 449-452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Clarification of generating mechanisms of various types of depression based on the Wakan-yaku theory for development of novel depressants2012
    • Author(s)
      Tohda M
    • Journal Title

      J. Trd. Med

      Volume: 29 Pages: 85-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] Sominone improves memory impairments and increases axonal density in Alzheimer's disease model mice, 5XFAD2011
    • Author(s)
      Joyashiki E, Matsuya Y, Tohda C
    • Journal Title

      Int. J. Neurosci

      Volume: 121 Pages: 181-190

    • DOI

      10.3109/00207454.2010.541571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] γ-Mangostin increases serotonin 2A/2C, muscarinic, histamine and bradykinin receptor mRNA expression2011
    • Author(s)
      Sukma M, Tohda M, Suksamran S, Tantisira B
    • Journal Title

      J Ethnopharmacol

      Volume: 135 Pages: 450-454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] Sominone improves memory impairments2011
    • Author(s)
      Joyashiki E., Matsuya Y., Tohda C.
    • Journal Title

      Int. J. Neurosci.,

      Volume: 121 Pages: 181-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Kamikihi-to (KKT) rescues axonal and synaptic degeneration associated with memory impairment in a mouse model of Alzheimer's disease, 5XFAD.2011
    • Author(s)
      Tohda C, Nakada R, Urano T, Okonogi A, Kuboyama T
    • Journal Title

      International Journal of Neuroscience

      Volume: 121(12) Pages: 641-648

    • DOI

      10.3109/00207454.2011.602809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439, KAKENHI-PROJECT-23700376

  • [Journal Article] Current and future therapeutic strategies for functional repair of spinal cord injury2011
    • Author(s)
      Tohda C
    • Journal Title

      Pharmacol Ther

      Volume: 132 Pages: 57-71

    • DOI

      10.1016/j.pharmthera.2011.05.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23110005, KAKENHI-PROJECT-23500439, KAKENHI-PROJECT-23700376

  • [Journal Article] Current and future therapeutic strategies2011
    • Author(s)
      Tohda C., Kuboyama T.
    • Journal Title

      Pharmacology & Therapeutics

      Volume: 132 Pages: 57-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons2011
    • Author(s)
      Bai Y.J., Tohda C, Zhu S., Hattori M., Komatsu K.
    • Journal Title

      J. Nat. Med

      Volume: 65 Pages: 417-423

    • DOI

      10.1007/s11418-011-0509-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406004, KAKENHI-PROJECT-23500439

  • [Journal Article] Active components from Siberian ginseng(Eleutherococcus senticosus) for protection of amyloidβ(25-35)-induced neuritic atrophy in cultured rat cortical neurons2011
    • Author(s)
      Bai Y. J., Tohda C., Zhu S., Hattori M., Komatsu K.
    • Journal Title

      J. Nat. Med.

      Volume: 65 Pages: 417-423

    • NAID

      10029461713

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406004

  • [Journal Article] Kamikihi-to (KKT) rescues axonal and synaptic2011
    • Author(s)
      Tohda C, Nakada R, Urano T, Okonogi A, Kuboyama T.
    • Journal Title

      Int. J. Neurosci.

      Volume: 121 Pages: 641-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] Active components from Siberian ginseng2011
    • Author(s)
      Bai Y, Tohda C, Zhu S, Hattori M, Komatsu K.
    • Journal Title

      J. Nat. Med.

      Volume: 65 Pages: 417-423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Journal Article] うつ病に立ち向かう和漢薬2010
    • Author(s)
      東田道久
    • Journal Title

      初心者にもわかる和漢薬一日セミナー要旨集

      Pages: 33-43

    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] Serotonin 2C receptor (5-HT2CR) mRNA editing-induced down-regulation of 5-HT2CR function in Xenopus oocytes : the significance of site C editing2010
    • Author(s)
      Tohda M, Hang PT, Kobayashi N, Matsumoto K
    • Journal Title

      J Pharmacol Sci

      Volume: 113 Pages: 362-367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] Enhanced expression of BCL2/adenovirus EIB 19-kDa-interacting protenin 3 mRNA, a candidate for intrinsic depression-related factor, and effects of imipramine in the frontal cortex of stressed mice.2010
    • Author(s)
      Tohda M, 他計4名
    • Journal Title

      Biol.Pham.Bull. 33

      Pages: 53-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] Developmental changes in serotonin 2C receptor mRNA editing in the ratcerebral cortex and primary cultured cortical neurons.2009
    • Author(s)
      Tohda M, 他計3名
    • Journal Title

      Biol.Pham.Bull. 32

      Pages: 289-292

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Journal Article] BNIP-3: A novel candidate for an intrinsic depression-related factor found in NG108-15 cells treated with Hochu-ekki-to, a traditional oriental medicine, or typical antidepressants2008
    • Author(s)
      Tohda, M., et. al.
    • Journal Title

      Neurosci. Res

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Influences of changes in serotonin 2C receptor mRNA editing on neuronal development and neurite outgrowth activity in rat brains and cultured cortical cells2008
    • Author(s)
      Hang, P.N.T, Tohda, M., Matsumoto, K
    • Journal Title

      Neurosci. Res (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] BNIP-3: A novel candidate for an intrinsic depression-related factor fbund in NG108-15 cells treated with Hochu-ekki-to, a traditional oriental medicine, or typical antidepressants.2008
    • Author(s)
      Tohda, M., 他計4名
    • Journal Title

      Neurosci. Res. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Inhibitory effects of Eleutherococcus senticosus extracts on amyloidβ(25-35)-induced neuritic atrophy and synaotic loss2008
    • Author(s)
      Tohda C., Ichimura M., Bai Y. J., Zhu S., Tanaka K., Komatsu K.
    • Journal Title

      JPS (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] BNIP-3: A novel candidate for an intrinsic depression-related factor found in NG108-15 cells treated with Hochu-ekki-to, a traditional oriental medicine, or typical antidepressants2008
    • Author(s)
      Tohda, M., Hayashi, H., Sukma, M., Tanaka, K
    • Journal Title

      Neurosci. Res (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Inhibitory effects of Eleutherococcus senticosus extracts on amyloid 13(25-35)-induced neuritic atrophy and synaptic loss2008
    • Author(s)
      Tohda, C., Ichimura, M., Bai, Y.J., Zhu, S., Tanaka, K., Komatsu, K
    • Journal Title

      JPS (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Influences of changes in serotonin 2C receptor mRNA editing on neuronal development and neurite outgrowth activity in rat brains and cultured cortical cells.2008
    • Author(s)
      Tohda, M., 他計3名
    • Journal Title

      Neurosci. Res. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Developmental changes in expression and self-editing of adenosine deaminase type 2 pre-mRNA and mRNA in rat brain and cultured cortical neurons2008
    • Author(s)
      Hang, P.N.T, Tohda, M., Matsumoto, K
    • Journal Title

      Neurosci. Res (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Learning-deficits and agenesis of synapses and myelinated axons in phosphoinositide-3 kinase-deficientmice.2007
    • Author(s)
      Tohda C., Nakanishi R., and Kadowaki M.
    • Journal Title

      Neurosignals 15

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Chotosan enhances Macrophage colony-stimulating factor mRNA expression in the ischemic rat brain and C6Bu-1 glioma cells2007
    • Author(s)
      Obi, R., Tohda, M., Zhao, Q., Obi, N., Hori, H., Murakami, Y., Goto, H., Shimada, Y., Ochiai, H., Matsumoto, K
    • Journal Title

      Biol. Pharm. Bull 30

      Pages: 2250-2256

    • NAID

      110006546420

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Withanoside IV improves hindlimb function by facilitating axonal regrowth and increase in peripheral nervous system myelin level after spinal cord injury2007
    • Author(s)
      Nakayama, N. Tohda, C
    • Journal Title

      Neurosci. Res 58

      Pages: 176-182

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Learning-deficits and agenesis of synapses and myelinated axons in phosphoinositide-3 kinase-deficient mice2007
    • Author(s)
      Tohda C., Nakanishi R., Kadowaki M.
    • Journal Title

      Neurosignals 15

      Pages: 293-306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Chotosan enhances Macrophage colony-stimulating factor mRNA expression in theischemic rat brain and C6Bu-1 glioma cells2007
    • Author(s)
      Obi, R., Tohda, M., et. al.
    • Journal Title

      Biol. Pharm. Bull 30

      Pages: 2250-2256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Withanoside IV improves hndlimb function by facilitating axonal regrowth and increase in peripheral system myelin level after spinal cord injury.2007
    • Author(s)
      Nakayama N, Tohda C.
    • Journal Title

      Neurosci.Res. (in press)

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] γ-Aminobutyric acid specifically inhibits progression of tubular fibrosis and atrophy in nephrectomized rats2007
    • Author(s)
      Sasaki, S., Tohda, C., Kim, M., Yokozawa, T
    • Journal Title

      Biol. Pharm. Bull 30

      Pages: 687-691

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] 鬱金類生薬の基原と品質.2007
    • Author(s)
      小松かつ子、佐々木陽平、東田千尋、田中謙
    • Journal Title

      Foods & Food Ingredients Journal of Japan 212

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Effects of Tokishakuyakusan on the ovary in hypophysectomized rats2007
    • Author(s)
      Chung, M., Tohda, M., Hattori, M
    • Journal Title

      J. Trad. Med 24

      Pages: 31-38

    • NAID

      110006224308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] γ-Aminobutyric acids pecifically inhibits progression of tubu lar fibrosis and atrophy in nephrectomized rats2007
    • Author(s)
      Sasaki S, Tohda C, Kim M, and Yokozawa T.
    • Journal Title

      Biol. Pharm. Bull 30

      Pages: 687-691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Effects of manganese complexes of curcumin and diacetylcurcumin on kainic acid-induced neurotoxic responses in the rat hippocampus2007
    • Author(s)
      Sumanont, Y, Murakami, Y, Tohda, M, Vajragupta, O, Watanabe, H, Matsumoto, K
    • Journal Title

      Biol. Pharm. Bull 30

      Pages: 1732-1739

    • NAID

      110006380259

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Withanoside IV improves hindlimb function by facilitating axonal regrowth and increase in peripheral nervous system myelin level after spinal cord injury2007
    • Author(s)
      Nakayama N., Tohda C.
    • Journal Title

      Neurosci. Res 58

      Pages: 176-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Chotosan, a kampo formula, ameliorates chronic cerebral hypoperfusion-induced deficits in object recognition behaviors and central cholinergic systems in mice2007
    • Author(s)
      Zhao, Q., Murakami, Y., Tohda, M., Obi, R., Shimada, Y., Matsumoto, K
    • Journal Title

      J Pharmacol Sci 103

      Pages: 360-373

    • NAID

      10024313412

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Withanoside IV improves hindlimb function by facilitating axonal regrowth and increase in peripheral nervous system myelin level after spinal cord injury.(2007)58, 176-182.2007
    • Author(s)
      Nakayama N. and Tohda C.
    • Journal Title

      Neurosci. Res. 58

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Effects of Tokishakuyakusan on hypothalamic pituitary aenylate cyclase activating polypeptide(PACAP)and PACAP type I receptor(PAC1)expression in hypophysectomized and ovariectomized rats2007
    • Author(s)
      Chung, M., Nakamura, N., Tohda, M., Hattori, M
    • Journal Title

      J. Trad. Med 24

      Pages: 24-30

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Learning-deficits and agenesis of synapses and myelinated axons in phosphoinositide-3 kinase-deficient mice2007
    • Author(s)
      Tohda, C., Nakanishi, R., Kadowaki, M
    • Journal Title

      Neurosignals 15

      Pages: 293-306

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] γ-Aminobutyric acid specifically inhibits progression of tubular fibrosis and atrophy in nephrectomized rats.2007
    • Author(s)
      Sasaki S., Tohda C., Kim M., and Yokozawa T.
    • Journal Title

      Biol. Pharm. Bull. 30

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Effects of Tokishakuyakusan on the ovary in hypophysectomized rats2007
    • Author(s)
      Chung M.H., Tohda M.et al.
    • Journal Title

      J. Trad. Med. 24

      Pages: 31-38

    • NAID

      110006224308

    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Plant origins and qualities of Curcuma drugs2007
    • Author(s)
      Komatsu, K., Sasaki, Y., Tohda, C., Tanaka, K
    • Journal Title

      Foods & Food Ingredients Journal of Japan 212

      Pages: 345-356

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Withanoside IV and its active metabolite, sominone, attenuate Aβ(25-35)-induced neurodegeneration2006
    • Author(s)
      Kuboyama, T., Tohda, C., Komatsu, K
    • Journal Title

      Eur. J. Neurosci 23

      Pages: 1417-1427

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Metabolite 1 of protopanaxadiol-type saponins, an axonal regenerative factor, stimulates teneurin-2 linked by PI3-kinase cascade2006
    • Author(s)
      Tohda, C., Hashimoto, I., Kuboyama, T., Komatsu, K
    • Journal Title

      Neuropsychopharmacology 31

      Pages: 1158-1164

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Characterization of anti-neurodegenerative effects of Polygala tenuifolia in Aβ(23-35)-treated cortical neurons.2006
    • Author(s)
      Naito R., Tohda C.
    • Journal Title

      Biol.Pharm.Bull. 29

      Pages: 1892-1896

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Comparison of anti-inflammatory activities of six Curcuma rhizomes : a possible curcuminoid-independent pathway mediated by Curcuma phaeocaulis extract2006
    • Author(s)
      Tohda C., Nakayama N., Hatanaka F., Komatsu K.
    • Journal Title

      Evidence-based Complementary and Alternative Medicine 3(2)

      Pages: 255-260

    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Withanoside IV and its active metabolite, sominone, attenuate Aβ(25-35)-induced neurodegeneration.2006
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      Eur.J.Neurosci (In press)

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Survey on enigma of ethno-medicines2006
    • Author(s)
      Komatsu, K, Tohda, C
    • Journal Title

      Development of Medicinal Plant(CMC Publishing Co., Ltd.)

      Pages: 278-298

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Comparison of anti-inflammatory activities of six Curcuma rhizomes: a possible curcuminoid-independent pathway mediated by Curcuma phaeocaulis extract2006
    • Author(s)
      Tohda, C., Nakayama, N., Hatanaka, F., Komatsu, K
    • Journal Title

      Evid. Based Complement. Alternat. Med 3

      Pages: 255-260

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus2006
    • Author(s)
      Tohda C., Tamura T., Matsuyama S., Komatsu K.
    • Journal Title

      Br. J. Pharmacol. 149

      Pages: 532-541

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Comparison of anti-inflammatory activities of six Curcuma rhizomes: a possible curcuminoid-independent pathway mediated by Curcuma phaeocaulis extract2006
    • Author(s)
      Tohda, C., Nakayama, N., Hatanalka, F., Komatsu, K
    • Journal Title

      Evidence-based Complementary and Alternative Medicine 3

      Pages: 255-260

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Metabolite 1 of protopanaxadiol-type saponins, an axonal regenerative factor, stimulates teneurin-2 linked by P13-kinase cascade2006
    • Author(s)
      Tohda C., Hashimoto I., Kuboyama T., Komatsu K.
    • Journal Title

      Neuropsychopharmacology (In press)

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Molecular pathopharmacology of 5-HT2C receptors and the RNA editing in the brain.2006
    • Author(s)
      Tohda M., et al.
    • Journal Title

      J Pharmacol Sci. 100

      Pages: 427-432

    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Withanoside IV and its active metabolite, sominone, attenuate AB(25-35)-induced neurodegeneration.2006
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      Eur. J. Neurosci 23

      Pages: 1417-1426

    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Axonal maturation and anti-dementia effect by Astragalus mongholicus.2006
    • Author(s)
      Tohda C., Tamura T., Matsuyama S., Komatsu K.
    • Journal Title

      Br. J. Pharmacol. 149

      Pages: 532-541

    • Data Source
      KAKENHI-PROJECT-17659202

  • [Journal Article] Promotion of axonal maturation and inhibition of dementia by Astragalus mongholicus2006
    • Author(s)
      Tohda, C., Tamura, T., Matsuyama, S., Komatsu, K
    • Journal Title

      British. J. Pharmacol 149

      Pages: 532-541

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Metabolite 1 of protopanaxadiol-type saponins, an axonal regenerative factor, stimulates teneurin-2 linked by PI3-kinase cascade2006
    • Author(s)
      Tohda C., Hashimoto L., Kuboyama T., Komatsu K.
    • Journal Title

      Neuropsychopharmacology 30

      Pages: 1158-1164

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Withanoside IV and its active metabolite, sominone, attenuate Aβ(23-35)-induced neurodegeneration.2006
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      Eur.J.Neurosci 23

      Pages: 1417-1427

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Effect of coffee on dementia2006
    • Author(s)
      Tohda, C., Komatsu, K, Namura, N., Hatori, M
    • Journal Title

      Sciences and functions of coffee(I K Publishing Co., Ltd.)

      Pages: 50-58

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Axonal maturation and anti-dementia effect by Astragalus mongholicus2006
    • Author(s)
      Tohda C., Tamura T., Matsuyama S., Komatsu K.
    • Journal Title

      Br. J. Pharmacol. 149

      Pages: 532-541

    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Comparison of anti-inflammatory activities of six Curcuma rhizomes: a possible curcuminoid-independent pathway mediated by Curcuma phaeocaulis extract.2006
    • Author(s)
      Tohda C., Nakayama N., Hatanalka F. and Komatsu K.
    • Journal Title

      Evidence-based Complementary and Alternative Medicine 3

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Characterization of anti-neurodegenerative effects of Polygala tenuifolia in Ap(25-35)-treated cortical neurons2006
    • Author(s)
      Naito, R., Tohda, C
    • Journal Title

      Biol. Pharm. Bull 29

      Pages: 1892-1896

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Metabolite 1 of protopanaxadiol-type saponins, an axonal regenerative factor, stimulates teneurin-2 linked by P13-kinase cascade2006
    • Author(s)
      Tohda C., Hashimoto I., Kuboyama T., Komatsu K.
    • Journal Title

      Neuropsychopharmacology (in press)

    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Prevention of kainic acid-induced changes in nitric oxide level and neuronal cell damage in the rat hippocampus by maneanese complexes of curcumin and diacetylcurcumin2006
    • Author(s)
      Sumanont, Y., Murakami, Y., Tohda, M., Vajragupta, O., Watanabe, H., Matsumoto, K
    • Journal Title

      Life Sci 78

      Pages: 1884-1891

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Promotion of axonal maturation and inhibition of dementia by Astragalus mongholicus.2006
    • Author(s)
      Tohda C., Tamura T., Matsuyama S. and Komatsu K.
    • Journal Title

      British. J. Pharmacol. 149

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Comparison of anti-inflammatory activities of six Curcuma rhizomes : a possible curcuminoid-independent pathway mediated by Curcuma phaeocaulis extract2006
    • Author(s)
      Tohda C., Nakayama N., Hatanaka F., Komatsu K.
    • Journal Title

      Evidence-based Complementary and Alternative Medicine (in press)

    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Molecular pathopharmacology of 5-HT2C receptors and the RNA editing in the brain.2006
    • Author(s)
      Tohda, M., 他計3名
    • Journal Title

      J Pharmacol Sci. 100

      Pages: 427-432

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Withanoside IV and its active metabolite, sominone, attenuate Aβ(25-35)-induced neurodegeneration.2006
    • Author(s)
      Kuboyama T., Tohda C. and Komatsu K.
    • Journal Title

      Eur. J. Neurosci. 23

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Characterization of anti-neurodegenerative effects of Polygala tenuifolia in Aβ(25-35)-treated cortical neurons.2006
    • Author(s)
      Naito R. and Tohda C.
    • Journal Title

      Biol. Pharm. Bull. 29

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] promotion of axonal maturation and inhibition of dementia by Astragalus mongholicus.2006
    • Author(s)
      Tohda C., Tamura T., Matsuyama S., Komatsu K.
    • Journal Title

      Br.J.Pharmacol., 149

      Pages: 532-541

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Comparison of anti-inflammatory activities of six Curcuma rhizomes : a possible curcuminoid-independent pathway mediated by Curcuma phaeocaulis extract.2006
    • Author(s)
      Tohda C., Nakayama N, Hatanalka F., Komatsu K.
    • Journal Title

      Evidence-based Complementary and Alternative Medicine 3

      Pages: 255-260

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Metabolite I of protopanaxadiol-type saponins, axonal regenerative factor, stimulates teneurin-2 linked by PI3-kinase cascade2006
    • Author(s)
      Tohda C., Hashimoto I.
    • Journal Title

      Neuropsychopharmacology 31

      Pages: 1158-1164

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Withanoside IV and its active metabolite, sominone, attenuate Aβ(25-35)-induced neurodegeneration.2006
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      Eur.J.Neurosci (in press)

    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Effects of coffee on dementia2006
    • Author(s)
      Tohda, C., Komatsu, K., Nakamura, N., Hattori, M
    • Journal Title

      Science and Function of coffee

      Pages: 50-58

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action2006
    • Author(s)
      Vajragupta, O, Boonyarat, C, Murakami, Y, Tohda, M, Musatmoto, K, Olson, AJ, Watanabe, H
    • Journal Title

      Free Radic Res 40

      Pages: 685-695

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Metabolite 1 of protopanaxadiol-type saponins, an axonal regenerative factor, stimulates teneurin-2 linked by PI3-kinase cascade2006
    • Author(s)
      Tohda, C., Hashimoto, I., Kuboyama, T., Komatsu, K
    • Journal Title

      Neuropsychopharmacology 30

      Pages: 1158-1164

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Comparison of anti-inflammatory activities of six Curcuma rhizomes: a possiblecurcuminoid-independent pathway mediated by Curcuma phaeocaulis extract2006
    • Author(s)
      Tohda C., Nakayama N., Hatanaka F., Komatsu K.
    • Journal Title

      Evid. Based Complement. Alternat. Med. 3

      Pages: 255-260

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Metabolite 1 of protopanaxadiol-type saponins, an axonal regenerative factor, stimulates teneurin-2 linked by PI3-kinase cascade.2006
    • Author(s)
      Tohda C., Hashimoto I., Kuboyama T. and Komatsu K.
    • Journal Title

      Neuropsychopharmacology 31

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Protective effect of grape seed polyphenols against high glucose induced-oxidative stress2006
    • Author(s)
      Fujii, H.,Yokozawa, T., Kim, Y.A. Tohda, C., Nonaka, G
    • Journal Title

      Biosci.. Biotech. Biochem 70

      Pages: 2104-2111

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Molecular pathopharmacology of 5-HT2C receptors and the RNA editing in the brain2006
    • Author(s)
      Tohda, M., Nomura, M., Nomura, Y
    • Journal Title

      J Pharmacol Sci 100

      Pages: 427-432

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus2006
    • Author(s)
      Tohda, C., Tamura, T., Matsuyama, S., Komatsu, K
    • Journal Title

      Br. J. Pharmacol 149

      Pages: 532-541

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Protective effect of grape seed polyphenols against high glucose induced-oxidative stress.2006
    • Author(s)
      Fujii H., Yokozawa T., Kim Y. A., Tohda C., Nonaka G.
    • Journal Title

      Biosci. Biotech. Biochem. 70

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Withanoside IV and its active metabolite, sominone, attenuate A13(25-35)-induced neurodegeneration2006
    • Author(s)
      Kuboyama, T., Tohda, C., Komatsu, K
    • Journal Title

      Eur. J. Neurosci 23

      Pages: 1417-1426

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Influence of Amla(Emblica officinalis Gaertn.)on Hypercholesterolemia and Lipid Peroxidation in Cholesterol-Fed Rats2005
    • Author(s)
      Kim, H.J., Yokozawa, T., Kim, H.Y., Tohda, C., Rao, T.P., Juneja, L.R
    • Journal Title

      J. Nutr. Sci. Vitaminol 51

      Pages: 413-418

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Influence of Amla(Emblica officinalis Gaertn.)on Hypercholesterolemia and Lipid Peroxidation in Cholesterol-Fed Rats.2005
    • Author(s)
      Kim H. J., Yokozawa T., Kim H. Y., Tohda C., Rao T. P. and Juneja L. R.
    • Journal Title

      J. Nutr. Sci. Vitaminol. 51

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Ginseng drugs-Molecular and Chemical Characteristics and Possibility as Antidementia Drugs2005
    • Author(s)
      Komatsu K., Tohda C., Zhu S.
    • Journal Title

      Current Topics in Nutraceutical Research 3

      Pages: 47-64

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14406030

  • [Journal Article] Supressive effects of isorhynchophyline on 5-HT2A receptor function in the brain: Behavioral and electrophysiological studies2005
    • Author(s)
      Matsumoto, K., Morishige, R., Murakami,Y., Tohda, M., Takayama, H., Sakakibara, I., Watanabe, H
    • Journal Title

      Eur. J. Pharmacol 517

      Pages: 191-199

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] The mRNA expression differences of RNA editing enzymes in differentiated and undifferentiated NG108-15 cells2005
    • Author(s)
      Sukma, M., Tohda, M., Watanabe, H., Matsumoto, K
    • Journal Title

      J Pharmacol Sci 98

      Pages: 467-70

    • NAID

      10025729889

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Effects of Choto-san and Its Related Constituents on Endogenous Antioxidant Systems.2005
    • Author(s)
      Mahakunakorn P., Tohda M., et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin 28

      Pages: 53-57

    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Search for natural products related to regeneration of the neuronal network.2005
    • Author(s)
      Tohda C., Kuboyama T. and Komatsu K.
    • Journal Title

      Neurosignals 14

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Scientific basis for the anti-dementia drugs of constituents from Ashwagandha( Withania somnifera)2005
    • Author(s)
      Tohda, C., Komatsu, K., Kuboyama, T
    • Journal Title

      J. Traditional Med 22(Suppl.1)

      Pages: 176-182

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] The mRNA expression differences of RNA editing enzymes in differentiated and undifferentiated NG108-15 cells.2005
    • Author(s)
      Sukma M., Tohda M., et al.
    • Journal Title

      Journal of Pharmacological Sciences 98

      Pages: 467-470

    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] The Effects of Choto-san on the mRNA Expression of Alzheimer's Disease Related Factors in the Permanent Ischemic Rat Brain.2005
    • Author(s)
      Hayashi H., Tohda M., et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin 28

      Pages: 744-746

    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Neuritic regeneration and synaptic reconstruction induced by withanolide A.2005
    • Author(s)
      Kuboyama T., Tohda C. and Komatsu K.
    • Journal Title

      British J. Pharmacol. 144

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Effects of Choto-san and its related constituents on endogenous antioxidant systems2005
    • Author(s)
      Mahakunakorn, P., Tohda, M., Matsumoto, K., Murakami, Y., Watanabe, H
    • Journal Title

      Biol. Pharm. Bull 28

      Pages: 53-57

    • NAID

      110003665770

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Social isolation stress-induced oxidative damage in mouse brain and its modulation by majonoside-R2, a Vietnamese ginseng saponin2005
    • Author(s)
      Huong, N.T., Murakami, Y., Tohda, M., Watanabe, H., Matsumoto, K
    • Journal Title

      Biol Pharm Bull 28

      Pages: 1389-1393

    • NAID

      110003666433

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Ginsengs Drugs-Molecular and chemical characteristics and possibility as antidementia drugs2005
    • Author(s)
      Komatsu K., Tohda C., Zhu S.
    • Journal Title

      Current topics in Nutraceutical Research 3(1)

      Pages: 47-65

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Neuritic regeneration and synaptic reconstruction induced by withanolide A2005
    • Author(s)
      Kuboyama, T., Tohda, C., Komatsu, K
    • Journal Title

      Br. J Pharmacol 144

      Pages: 961-971

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Neuritic regeneration and synaptic reconstruction induced by withanolide A2005
    • Author(s)
      Kuboyama, T., Tohda, C., Komatsu, K
    • Journal Title

      British J Pharmacol 144

      Pages: 961-971

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Neuritic regeneration and synaptic reconstruction induced by withanolide A2005
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      Br. J. Pharmacol. 144

      Pages: 961-971

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Neuritic regeneration and synaptic reconstruction induced by withanolide A2005
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      Br.J.Pharmacol. 144

      Pages: 961-971

    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Neuritic regeneration and synaptic reconstruction induced by withanolide A2005
    • Author(s)
      Kuboyama T., Tohda C., Komatsu K.
    • Journal Title

      British J.Pharmacol. 144

      Pages: 961-971

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Ginsengs Drugs - Molecular and chemical characteristics and possibility as antidementia drugs2005
    • Author(s)
      Komatsu, K., Tohda, C., Zhu, S
    • Journal Title

      Current topics in Nutraceutical Research 3

      Pages: 47-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Corymine potentiates NMDA-induced current in Xenopus oocytes expressing NR1a/NR2B glutamate receptors2005
    • Author(s)
      Leewanich, P., Tohda, M., Takayama, H., Sophasan, S., Watanabe, H., Matsumoto, K
    • Journal Title

      Pharmacol. Sci 98

      Pages: 58-65

    • NAID

      10025727941

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Scientific basis for the anti-dementia drugs of constituents from Ashwagandha (Withania somnifera)2005
    • Author(s)
      Tohda C., Komatsu K., Kuboyama T.
    • Journal Title

      和漢医薬学雑誌 22(Suupl.1)

      Pages: 176-182

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Ginseng drugs - Molecular and Chemical Characteristics and Possibility as Antidementia Drugs2005
    • Author(s)
      Komatsu K., Tohda C., Zhu S.
    • Journal Title

      Current Topics in Nutraceutical Research 3

      Pages: 47-64

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14406030

  • [Journal Article] Hayashi, H., Tohda, M., Matsumoto, K., Murakami, Y., Watanabe, H2005
    • Author(s)
      Hayashi, H., Tohda, M., Matsumoto, K., Murakami, Y., Watanabe, H
    • Journal Title

      Biol. Pharm. Bull 28

      Pages: 744-746

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Search for natural products related to regeneration of the neuronal network2005
    • Author(s)
      Tohda, C., Kuboyama, T., Komatsu, K
    • Journal Title

      Neurosignals 14

      Pages: 34-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Search for natural products related to regeneration of the neuronal network2005
    • Author(s)
      Tohda C., Kuboyama T., Komatsu K.
    • Journal Title

      NeuroSignals 14(1-2)

      Pages: 34-45

    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Scientific basis for the anti-dementia drugs of constituents from Ashwagandha(Withania somnifera).2005
    • Author(s)
      Tohda C., Komatsu K. and Kuboyama T.
    • Journal Title

      和漢医薬学雑誌 22

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Preventive effect of chotosan, a kampo medicine, on transient ischemia-induced learning deficit is mediated by stimulation of muscarinic ml but not nicotinic receptor2005
    • Author(s)
      Zhao, Q., Murakami, Y., Tohda, M., Watanabe, H., Matsumoto, K
    • Journal Title

      Biol Pharm Bull 28

      Pages: 1873-1878

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Choto-san, a Kampo formula, improves chronic cerebral hypoperfusion-induced spatial learning deficit via stimulation of muscarinic M1 receptor2005
    • Author(s)
      Murakami, Y., Zhao, Q., Harada, K., Tohda, M., Watanabe, H., Matsumoto, K
    • Journal Title

      Pharm. Biochem. Behay 81

      Pages: 616-625

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Journal Article] Enigma of ethno-medicines: survey on ginseng drugs in the world-diversity analysis and possibility as antidementia drug2005
    • Author(s)
      Komatsu, K., Tohda, C
    • Journal Title

      New Development of Medicinal Plant(CMC Publishing Co., Ltd.)

      Pages: 302-324

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Journal Article] Ginsengs Drugs-Molecular and chemical characteristics and possibility as antidementia drugs.2005
    • Author(s)
      Komatsu K., Tohda C. and Zhu S.
    • Journal Title

      Current topics in Nutraceutical Research 3

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] The mystery of ethnomedicines: Pursuing Ginseng drugs in the world2005
    • Author(s)
      Komatsu, K., Tohda, C
    • Journal Title

      New Development of Medical Plant

      Pages: 302-324

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Journal Article] Aβ(25-35)-induced memory impairment, axonal atrophy and synaptic loss are ameliorated by M1, a metabolite of protopanaxadiol-type saponins.2004
    • Author(s)
      Tohda C., Matsumoto N., Zou K., Meselhy M.R., Komatsu K.
    • Journal Title

      Neuropsychopharmacology 29

      Pages: 860-868

    • Data Source
      KAKENHI-PROJECT-14406030

  • [Journal Article] Aβ(25-35)-induced memory impairment, axonal atrophy and synaptic loss are ameliorated by M1, a metabolite of protopanaxadiol-type saponins2004
    • Author(s)
      Tohda C., Matsumoto N., Zou K., Meselhy M.R., Komatsu K.
    • Journal Title

      Neuropsychopharmacology 29

      Pages: 860-868

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14406030

  • [Journal Article] Repair of amyloid β(25-35)-induced memory impairment and synaptic loss by a Kampo Formula, Zokumei-to2003
    • Author(s)
      Tohda C., Tamura T., Komatsu K.
    • Journal Title

      Brain Research 990

      Pages: 141-147

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14406030

  • [Journal Article] Effects of Curcuma Drugs on Vasomotion in Isolated Rat Aorta2003
    • Author(s)
      Sasaki Y., Goto H., Tohda C., Hatanaka F., Shibahara N., Shimada Y., Terasawa K., Komatsu K.
    • Journal Title

      Biol.Pharm.Bull. 26(8)

      Pages: 1135-1143

    • NAID

      110003655065

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14406030

  • [Patent] 神経変性疾患の予防、治療及び/又は改善剤2021
    • Inventor(s)
      東田千尋、長瀬綸沙
    • Industrial Property Rights Holder
      国立大学法人富山大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-077150
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Patent] ユビキチン―プロテアソーム系の活性化剤、およびその利用2020
    • Inventor(s)
      甲斐田大輔、東田千尋、伊野部智由、
    • Industrial Property Rights Holder
      富山大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-114185
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Patent] 軸索伸展剤2020
    • Inventor(s)
      東田千尋、楊熙蒙
    • Industrial Property Rights Holder
      富山大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-139980
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Patent] ユビキチン－プロテアソーム系の活性化剤、およびその利用2020
    • Inventor(s)
      甲斐田大輔、東田千尋、伊野部智由
    • Industrial Property Rights Holder
      甲斐田大輔、東田千尋、伊野部智由
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-114185
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K21247

  • [Patent] ペリオスチン及びＰＫＭ２の分泌促進剤 PCT出願：PCT/JP2018/25119 出願日 ：平成３０年７月２日 出願人 ：国立大学法人富山大学2018
    • Inventor(s)
      東田千尋、小谷篤
    • Industrial Property Rights Holder
      東田千尋、小谷篤
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Patent] 神経回路網の再構築・賦活剤2017
    • Inventor(s)
      東田千尋，小松かつ子
    • Industrial Property Rights Holder
      東田千尋，小松かつ子
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-119960
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Patent] アルツハイマー病の治療剤を含む、神経細胞の軸索の機能不全が関与する疾患の治療剤2017
    • Inventor(s)
      東田千尋、松谷裕二、杉本健士、
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-119963
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Patent] 記憶改善用ペプチド2017
    • Inventor(s)
      東田千尋、郭太乙、宮崎博之
    • Industrial Property Rights Holder
      株式会社日本生物製剤、富山大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Acquisition Date
      2017
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Patent] ペリオスチン及びＰＫＭ２の分泌促進剤2017
    • Inventor(s)
      東田千尋、小谷篤
    • Industrial Property Rights Holder
      富山大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-201435
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Patent] 記憶改善用ペプチド2017
    • Inventor(s)
      東田千尋、郭太乙、宮崎博之
    • Industrial Property Rights Holder
      日本生物製剤
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-02-14
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Patent] 記憶改善用ペプチド2017
    • Inventor(s)
      東田千尋、郭太乙、宮崎博之
    • Industrial Property Rights Holder
      株式会社日本生物製剤、国立大学法人富山大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Acquisition Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Patent] 神経回路網の再構築・賦活剤2017
    • Inventor(s)
      東田千尋、小松かつ子
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-119960
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Patent] 神経回路網の再構築・賦活剤2016
    • Inventor(s)
      東田千尋，小松かつ子
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-08-18
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Patent] 神経回路網の再構築・賦活用医薬または食品2015
    • Inventor(s)
      東田千尋、久保山友晴、楊志友
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-130692
    • Filing Date
      2015-06-30
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Patent] 神経回路網の再構築・賦活用医薬または食品　 国内出願番号：2015
    • Inventor(s)
      東田千尋、久保山友晴、楊志友
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-130692
    • Filing Date
      2015-06-30
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Patent] アルツハイマー病等を含む神経疾患の１，２５Ｄ３－ＭＡＲＲＳが関与する治療薬及び治療法2015
    • Inventor(s)
      東田千尋
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-150222
    • Filing Date
      2015-07-30
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Patent] 神経回路網の再構築・賦活剤2015
    • Inventor(s)
      東田千尋、小松かつ子
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-161125
    • Filing Date
      2015-08-18
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Patent] 神経回路網の再構築・賦活剤2015
    • Inventor(s)
      東田千尋，小松かつ子
    • Industrial Property Rights Holder
      東田千尋，小松かつ子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015
    • Acquisition Date
      2017
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Patent] 神経回路網の再構築・賦活剤2015
    • Inventor(s)
      東田千尋、小松かつ子
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-161125
    • Filing Date
      2015-08-18
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Patent] アルツハイマー病の治療剤を含む、神経細胞の軸索の機能不全が関与する疾患の治療剤2015
    • Inventor(s)
      東田千尋、松谷裕二、杉本健士
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-04-21
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Patent] 脊髄損傷慢性期の機能改善剤2014
    • Inventor(s)
      東田千尋、久保山友晴、田辺紀生
    • Industrial Property Rights Holder
      国立大学法人富山大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-157268
    • Filing Date
      2014-08-01
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Patent] アルツハイマー病等を含む神経疾患の1,25D3-MARRSが関与する治療薬及び治療法2013
    • Inventor(s)
      東田千尋
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-07-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Patent] アルツハイマー病の治療薬と治療2013
    • Inventor(s)
      東田千尋
    • Industrial Property Rights Holder
      東田千尋
    • Industrial Property Number
      2013-008136
    • Filing Date
      2013-01-21
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Patent] アルツハイマー病等を含む神経疾患の1,25D_3-MARRS が関与する治療薬及び治療法2013
    • Inventor(s)
      東田千尋
    • Industrial Property Rights Holder
      レジリオ株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-07-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Patent] アルツハイマー病の治療薬と治療法2013
    • Inventor(s)
      東田千尋
    • Industrial Property Rights Holder
      東田千尋
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-008136
    • Filing Date
      2013-01-21
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Patent] 神経細胞死抑制剤2008
    • Inventor(s)
      根本 英雄、東田 千尋、松谷 裕二
    • Industrial Property Rights Holder
      大鵬薬品工業株式会社
    • Industrial Property Number
      2008-012642
    • Filing Date
      2008-01-23
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] ADHD関連疾患治療剤2008
    • Inventor(s)
      東田千尋、山田昌司、鈴木啓仁
    • Industrial Property Rights Holder
      明治乳業株式会社
    • Filing Date
      2008-02-18
    • Description
      「研究成果報告書概要(和文)」より
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] ADHD関連疾患治療剤2008
    • Inventor(s)
      東田 千尋, 山田 昌司, 鈴木 啓仁
    • Industrial Property Rights Holder
      明治乳業株式会社
    • Filing Date
      2008-02-18
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] 神経細胞死抑制剤2008
    • Inventor(s)
      根本英雄、東田千尋、松谷裕二
    • Industrial Property Rights Holder
      大鵬薬品株式会社
    • Industrial Property Number
      2008-012642
    • Filing Date
      2008-01-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] 脊髄損傷治療剤2007
    • Inventor(s)
      東田千尋, 中山なつき, 山田昌司, 鈴木啓仁
    • Industrial Property Rights Holder
      明治乳業株式会社
    • Filing Date
      2007-01-30
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] 脊髄損傷治療剤2007
    • Inventor(s)
      東田千尋、中山なつき、山田昌司、鈴木啓仁
    • Industrial Property Rights Holder
      明治乳業株式会社
    • Filing Date
      2007-01-30
    • Description
      「研究成果報告書概要(和文)」より
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] ADHD関連疾患治療剤2007
    • Inventor(s)
      東田千尋、山田昌司、鈴木啓仁
    • Industrial Property Rights Holder
      明治乳業株式会社
    • Industrial Property Number
      2007-038498
    • Filing Date
      2007-02-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] 脊髄損傷治療剤2006
    • Inventor(s)
      東田千尋、中山なつき、山田昌司、鈴木啓仁
    • Industrial Property Rights Holder
      明治乳業株式会社
    • Industrial Property Number
      2006-037169
    • Filing Date
      2006-02-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] 脊髄損傷治療剤2006
    • Inventor(s)
      東田 千尋, 中山 なつき, 山田 昌司, 鈴木 啓仁
    • Industrial Property Rights Holder
      明治乳業株式会社
    • Filing Date
      2006-02-14
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] 注意欠陥多動性障害(ADHD)モデルマウス2006
    • Inventor(s)
      東田千尋、門脇真
    • Industrial Property Rights Holder
      富山大学
    • Industrial Property Number
      2006-177718
    • Filing Date
      2006-06-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] アルツハイマー型の記憶障害の予防・改善剤2006
    • Inventor(s)
      東田千尋、内藤理絵、横澤隆子
    • Industrial Property Rights Holder
      富山大学
    • Industrial Property Number
      2006-055982
    • Filing Date
      2006-03-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] 漢方処方による神経回路網再構築剤および神経回路網再構築方法.2005
    • Inventor(s)
      東田千尋、小松かつ子
    • Industrial Property Rights Holder
      富山大学
    • Filing Date
      2005-12-20
    • Description
      「研究成果報告書概要(和文)」より
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Patent] 漢方処方による神経回路網再構築剤および神経回路網の再構築方法2005
    • Inventor(s)
      東田千尋, 小松かつ子
    • Industrial Property Rights Holder
      富山大学
    • Filing Date
      2005-12-07
    • Data Source
      KAKENHI-PROJECT-17659202

  • [Patent] 漢方処方による神経回路網再構築剤および神経回路網再構築方法2005
    • Inventor(s)
      東田千尋, 小松かつ子
    • Industrial Property Rights Holder
      富山医科薬科大学
    • Filing Date
      2005-12-20
    • Description
      「研究成果報告書概要(和文)」より
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Patent] 神経回路網再構築剤および神経回路網再構築方法2004
    • Inventor(s)
      東田 千尋, 小松かつ子, 久保山 友晴
    • Industrial Property Rights Holder
      富山医科薬科大学
    • Industrial Property Number
      2004-370299
    • Filing Date
      2004-12-22
    • Data Source
      KAKENHI-PROJECT-14406030

  • [Patent] 漢方処方による神経回路網再構築剤および神経回路網再構築方法2004
    • Inventor(s)
      東田 千尋, 小松 かつ子
    • Industrial Property Rights Holder
      富山医科薬科大学
    • Industrial Property Number
      2004-370300
    • Filing Date
      2004-12-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14406030

  • [Patent] 神経回路網再構築剤および神経回路網再構築方法2004
    • Inventor(s)
      東田 千尋, 小松 かつ子, 久保山 友晴
    • Industrial Property Rights Holder
      富山医科薬科大学
    • Industrial Property Number
      2004-370299
    • Filing Date
      2004-12-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14406030

  • [Presentation] Effects of sibiricose A5, a constituent of Polygalae Radix, on recovery of memory in the mouse model of Alzheimer’s disease.2022
    • Author(s)
      Tomoharu Kuboyama, Yuta Arake, Misaki Nagumo, Seiya Kominato, Chihiro Tohda.
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgenin promotes long-distance axonal regeneration in the brain and recovers memory deficits in a mouse model of Alzheimer’s disease.2022
    • Author(s)
      Ximeng Yang, Chihiro Tohda.
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 局外生規2022に新規収載予定の単味生薬エキスについて2022
    • Author(s)
      内山奈穂子, 新井玲子,田中誠司, 丸山卓郎, 袴塚高志, 伊藤雅文, 若林健一, 武田修己, 小栗志織, 佐々木隆宏, 岡秀樹, 白鳥誠, 秋田幸子, 植村清美, 浅野年紀, 日向野太郎, 杉本智潮, 近藤誠三, 吉田雅昭, 西川加奈子, 山田修嗣, 山本豊, 玉木智生, 木内文之, 東田千尋, 竹林憲司, 小笠原勝, 中村高敏, ほか
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgeninがアルツハイマー病モデルマウスの脳内で軸索を再伸長させる分子メカニズムの解明2022
    • Author(s)
      楊熙蒙、東田千尋．．
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgeninはアルツハイマー病モデルマウスの脳内において軸索を再伸長させ記憶障害を改善する。2021
    • Author(s)
      楊熙蒙、東田千尋、
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgeninによるアルツハイマー病脳内での軸索修復作用と臨床研究への展開.2021
    • Author(s)
      東田 千尋、楊 熙蒙、稲田祐奈.
    • Organizer
      第94回日本生化学大会 シンポジウム「健康長寿社会に向けた和漢薬研究の新展開」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] ニクジュヨウエキスによる後縦靭帯骨化症の運動機能改善作用の検討.2021
    • Author(s)
      須山真聡、楊熙蒙、野本かおり、東田千尋．
    • Organizer
      第38回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 遠志成分sibiricose A5による抗アルツハイマー病作用．2021
    • Author(s)
      久保山友晴、荒毛優太、南雲美咲、小湊誠也、東田千尋．
    • Organizer
      第38回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 運動神経から骨格筋への軸索投射を促進する和漢薬の探索2021
    • Author(s)
      楊熙蒙、近藤麻布、東田千尋．
    • Organizer
      第38回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] ニクジュヨウエキスによる慢性期脊髄損傷の運動機能改善とそのメカニズム2021
    • Author(s)
      東田 千尋、小谷 篤、須山 真聡、野本かおり．
    • Organizer
      第38回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Recovery of memory deficits by overexpression of Shati/Nat8l in the hippocampus in a mouse model of Alzheimer’s disease.2021
    • Author(s)
      Chino K, Izuo N, Kuboyama T, Tohda C, Nitta A.
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgeninによって軸索が再伸長し記憶が改善する分子メカニズムの解明．）2021
    • Author(s)
      楊熙蒙、東田千尋.
    • Organizer
      第2回和漢医薬学会若手研究者フォーラム～芽吹け！若手の和漢薬研究～
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Skeletal muscle atrophy accelerates onset of cognitive impairment in Alzheimer’s disease via hemopexin delivery from muscle to the brain.2021
    • Author(s)
      Nagase T, Tohda C.
    • Organizer
      ISN-APSN School, Behavioral Analysis Models for Neurocjemical Research.
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgenin含有山薬エキスによる認知機能向上作用：マウスおよび健常人での検討.2021
    • Author(s)
      東田 千尋，楊 熙蒙、稲田 祐奈.
    • Organizer
      日本生薬学会第67回年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Effects of Cistanche tubulosa extract on motor function in ossification of posterior longitudinal ligment model mice.2021
    • Author(s)
      Suyama M, Yang X, Nomoto K, Tohda C.
    • Organizer
      第64回日本神経化学学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] CGK733がユビキチン-プロテアソーム系によるタンパク質分解を促進する機構の解析2021
    • Author(s)
      桒田桜子、伊野部智由、東田千尋、石神健、甲斐田大輔
    • Organizer
      第44回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K21247

  • [Presentation] Molecular mechanisms for long-distance axonal regeneration in the brain of Alzheimer’s disease model mouse.2021
    • Author(s)
      Yang X, Tohda C.
    • Organizer
      第64回日本神経化学学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] ロコモティブシンドロームに対するニクジュヨウエキスの効果．2021
    • Author(s)
      稲田祐奈、楊熙蒙、東田千尋．
    • Organizer
      第38回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Skeletal muscle atrophy increases hemopexin secretion and accelerates the onset of cognitive impairment in Alzheimer’s disease.2021
    • Author(s)
      Nagase T, Tohda C.
    • Organizer
      第64回日本神経化学学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Recovery of memory deficits by overexpression of Shati/Nat8l in the hippocampus in a mouse model of Alzheimer’s disease2021
    • Author(s)
      Chino K, Izuo N, Kuboyama T, Tohda C, Nitta A. .
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Investigation of drug effects on optic nerve growth in a mouse model of normal tension glaucoma2021
    • Author(s)
      Shibue S, Tohda C. .
    • Organizer
      第64回日本神経化学学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgenin is a candidate drug for stimulating axonal regeneration in the brain and recovering memory deficits in Alzheimer’s disease.2021
    • Author(s)
      Ximeng Yang, Chihiro Tohda.
    • Organizer
      第16回国際伝統医薬シンポジウム・富山2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Skeletal muscle atrophy-induced hemopexin accelerates onset of cognitive impairment in Alzheimer’s disease.2021
    • Author(s)
      Nagase T, Tohda C.
    • Organizer
      The 6th Toyama-Basel Joint Symposium 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Recovery from spinal cord injury via M2 microglial polarization induced by Polygalae Radix　遠志によるマイクログリアM2化を介した脊髄損傷からの回復．2021
    • Author(s)
      久保山友晴、小湊誠也、南雲美咲、東田千尋．
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgenin-rich yam extract enhances cognitive function: a placebo-controlled, randomized, double-blind, crossover study of healthy adults.2021
    • Author(s)
      Tohda C, Inada Y, Yang X.
    • Organizer
      第64回日本神経化学学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Trigonelline: A promising compound for the treatment of Alzheimer’s Disease2020
    • Author(s)
      Farid M. Mai, Yang X, Kuboyama T, Tohda C.
    • Organizer
      International Conference on Medicinal Plants, Pharmacognosy, Phytochemistry and Natural Products
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] HDAC3 inhibition ameliorates dystrophic axons and memory function via M2 microglia in a transgenic mouse model of Alzheimer’s disease.2020
    • Author(s)
      Kuboyama T, Tohda C.
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 認知症発症を加速する骨格筋分泌性因子2020
    • Author(s)
      長瀬綸沙，東田千尋．
    • Organizer
      第63回 日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 緑内障における視神経の保護および修復に対するdiosgeninの作用．2020
    • Author(s)
      真継理子、楊熙蒙、東田千尋．
    • Organizer
      富山薬学研究会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アミロイドβによる軸索変性に着目したアルツハイマー病予防・治療法の開発．2020
    • Author(s)
      久保山友晴, 楊熙蒙、東田千尋．
    • Organizer
      第37回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 海馬でのShati/Nat8lの過剰発現はアルツハイマー病モデルマウスの認知機能低下を改善する．2020
    • Author(s)
      千野翔、泉尾直孝、久保山友晴、東田千尋、新田淳美．
    • Organizer
      富山薬学研究会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] エゾウコギ葉エキスと骨砕補エキスの合剤による認知機能とストレス抵抗性に対するランダム化二重盲検試験2020
    • Author(s)
      東田千尋、松井三枝、稲田祐奈、楊熙蒙、久保山友晴、金原嘉之、渡り英俊．．
    • Organizer
      第37回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 新規マイオカインのPKM2 は慢性期脊髄損傷の運動機能を回復する2020
    • Author(s)
      須山真聡、菊池高広、中野葵、東田千尋．
    • Organizer
      第63回 日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 新規マイオカインPKM2の慢性期脊髄損傷改善作用と分泌様式の検討．2020
    • Author(s)
      須山真聡、東田千尋．
    • Organizer
      富山薬学研究会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgeninはアルツハイマー病の脳内において軸索を正しく再伸長させる．2020
    • Author(s)
      楊熙蒙、東田千尋
    • Organizer
      第37回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 認知症発症を加速する新規骨格筋分泌因子．2020
    • Author(s)
      長瀬綸沙、東田千尋．
    • Organizer
      富山薬学研究会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] ジオスゲニンによってアルツハイマー病の記憶障害が回復することに関与する、脳内の内分泌的作用の探索2020
    • Author(s)
      真継理子，楊熙蒙、中野葵，東田千尋．
    • Organizer
      第63回 日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アミロイドβによる軸索変性に着目したアルツハイマー病予防・治療法の開発2020
    • Author(s)
      久保山友晴、楊熙蒙、東田千尋
    • Organizer
      第37回和漢医薬学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07389

  • [Presentation] Diosgeninがアルツハイマー病モデルマウスの脳内において軸索を再伸長させる分子メカニズムの解明2020
    • Author(s)
      楊熙蒙、東田千尋．
    • Organizer
      第63回 日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] HDAC3 inhibition ameliorates dystrophic axons and memory function via M2 microglia in a transgenic mouse model of Alzheimer’s disease. アルツハイマー病モデルマウスにおいて、HDAC3阻害はマイクログリアのM2化を介して変性軸索を正常化させ、記憶回復作用を示す。2020
    • Author(s)
      Kuboyama T, Tohda C.
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 脊髄損傷慢性期の機能回復に有効な薬物と分子2020
    • Author(s)
      東田千尋
    • Organizer
      第63回 日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] HDAC3 inhibition ameliorates memory function via M2 microglia in a transgenic mouse model of Alzheimer’s disease.2019
    • Author(s)
      Kuboyama T, Tohda C.
    • Organizer
      Neuroscience 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07389

  • [Presentation] Effects of diosgenin on motor function and axonal outgrowth in chronic phase of spinal cord injury.2019
    • Author(s)
      Nakano A, Tohda C.
    • Organizer
      NEURO2019
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 和漢薬創薬に向けた基礎研究と臨床研究2019
    • Author(s)
      東田千尋
    • Organizer
      第 36 回 和漢医薬学会学術大会 シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 植物性医薬品の開発と薬用植物供給に向けた新たなアプローチ2019
    • Author(s)
      小松かつ子、東田千尋
    • Organizer
      第 36 回 和漢医薬学会学術大会 シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Acteoside improves muscle atrophy and motor function by inducing new myokine secretion in chronic spinal cord injury.2019
    • Author(s)
      Tohda C, Kodani A, Kikuchi T.
    • Organizer
      NEURO2019
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] A new unbeneficial myokine secreted from atrophied skeletal muscle accelerates the onset of Alzheimer’s disease.2019
    • Author(s)
      Nagase T, Tohda C.
    • Organizer
      Society for Neuroscience 49th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Axonal growth may lead to recovery from anxiety.2019
    • Author(s)
      Kuboyama T, Iseki R, Hosokawa H, Tohda C.
    • Organizer
      Toyama Forum for Academic Summit on “Dynamic Brain”
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] HDAC3 inhibition ameliorates memory function via M2 skewing of microglia in a transgenic mouse model of Alzheimer’s disease.2019
    • Author(s)
      uboyama T, Tohda C.
    • Organizer
      NEURO2019（第42回日本神経科学大会、第62回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-18K07389

  • [Presentation] Diosgenin elicits axonal regrowth in the brain and improves memory deficits in a mouse model of Alzheimer’s disease.2019
    • Author(s)
      Yang X, Tohda C.
    • Organizer
      NEURO2019
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 和漢薬研究による認知症治療への挑戦（Development of promising therapeutic drugs for dementia）2019
    • Author(s)
      東田千尋
    • Organizer
      富山・ミャンマー・医薬品・プライマリーヘルスケアシンポジウム2019
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 和漢薬を基盤とした神経疾患治療薬開発．2019
    • Author(s)
      東田千尋
    • Organizer
      日本学術会議 in 富山「富山から発信する学術研究とＳＤＧｓ対応」
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Trigonelline: A promising compound for the treatment of Alzheimer’s Disease.2019
    • Author(s)
      Farid M. Mai, Yang X, Kuboyama T, Tohda C.
    • Organizer
      Toyama Forum for Academic Summit on “Dynamic Brain”
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgenin prootes proper axonal regrowth in the brain and recovers memory deficits in a mouse model of Alzheimer’s disease.2019
    • Author(s)
      Yang X, Tohda C.
    • Organizer
      Toyama Forum for Academic Summit on “Dynamic Brain”
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] The molecular mechanism in the brain, as a New myokine PKM2 in chronic spinal cord injury.2019
    • Author(s)
      Kikuchi T, Kodani A, Tohda C.
    • Organizer
      NEURO2019
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] New myokine-mediated improvement of motor function and muscle atrophy in chronic spinal cord injury.2019
    • Author(s)
      Tohda C, Kodani A, Kikuchi T
    • Organizer
      Society for Neuroscience 49th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] HDAC3 inhibition ameliorates memory function via M2 microglia in a transgenic mouse model of Alzheimer’s disease.2019
    • Author(s)
      Kuboyama T, Tohda C.
    • Organizer
      Society for Neuroscience 49th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Naringenin promotes aβ clearance and ameliorates cognitive deficiency in Alzheimer’s disease and underlying mechanisms.2019
    • Author(s)
      Yang Z, Kuboyama T, Tohda C.
    • Organizer
      Society for Neuroscience 49th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 苦参成分matrineは神経伝導路再構築により慢性期脊髄損傷マウスの運動機能を回復させる2019
    • Author(s)
      久保山友晴、田辺紀生、東田千尋
    • Organizer
      第 36 回 和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgenin improve memory deficits in a mouse model of Alzheimer’s disease by promoting axonal regrowth in the brain.2019
    • Author(s)
      Yang X, Tohda C.
    • Organizer
      Society for Neuroscience 49th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 山薬エキスによる記憶力亢進作用の検討2019
    • Author(s)
      楊 熙蒙，東田 千尋
    • Organizer
      第 36 回 和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Neuroleukin enhances neuroleukin secretion from astrocytes and promotes axonal growth.2019
    • Author(s)
      Tanie Y, Tanabe N, Kuboyama T, Tohda C.
    • Organizer
      NEURO2019
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 認知機能改善を目指した和漢薬からのアプローチ．2019
    • Author(s)
      東田千尋
    • Organizer
      国立大学附置研究所・センター会議 第2部会シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 認知症発症を加速する骨格筋分泌性因子2019
    • Author(s)
      長瀬綸沙、東田千尋．
    • Organizer
      本薬学会北陸支部第131回例会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] HDAC3 inhibition ameliorates memory function via M2 skewing of microglia in a transgenic mouse model of Alzheimer’s disease.2019
    • Author(s)
      Kuboyama T, Tohda C.
    • Organizer
      NEURO2019
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Polygalae Radix extract prevents axonal degeneration and memory deficits in a transgenic mouse model of Alzheimer’s disease.2018
    • Author(s)
      Kuboyama Tomoharu., Tohda Chihiro.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アルカニンのアミロイドβ凝集に対する抑制作用の検討．2018
    • Author(s)
      細井　徹、今田　理裕、俵　明里、矢澤　恭介、東田　千尋、野村　靖幸、小澤　光一郎、
    • Organizer
      日本薬学会　第139年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] ジオスゲニン高濃度含有ヤマイモエキスによる健常人の認知機能向上：ランダム化二重盲検プラセボ対照クロスオーバー試験による検討.2018
    • Author(s)
      東田千尋、楊熙蒙、稲田祐奈、松井三枝、
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会合同年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] エゾウコギ葉水エキス経口投与による記憶向上作用と脳に移行する活性成分の同定2018
    • Author(s)
      山内唯、葛躍偉、吉松嘉代、小松かつ子、東田千尋、．
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会合同年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アクテオサイドによる骨格筋活性化を介した慢性期脊髄損傷の改善.2018
    • Author(s)
      菊池高弘、小谷篤、東田千尋、
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会合同年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アルカニンのアミロイドβ凝集・神経細胞毒性に対する作用．2018
    • Author(s)
      細井　徹、今田　理裕、俵　明里、矢澤　恭介、東田　千尋 、野村　靖幸、小澤　光一郎、
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] DiosgeninによるHSC70の減少はアルツハイマー病における軸索萎縮と記憶障害を改善する.2018
    • Author(s)
      楊熙蒙、東田千尋、
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会合同年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 脊髄損傷マウスの運動機能回復と軸索修復へのジオスゲニンの作用．2018
    • Author(s)
      中野葵、東田千尋、
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会合同年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アルツハイマー病モデルマウスにおいてHDAC3阻害はマイクログリアの表現型制御を介して記憶を改善させる．2018
    • Author(s)
      久保山友晴、東田千尋、
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会合同年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Development of promising therapeutic drugs for cognitive function.2018
    • Author(s)
      Chihiro Tohda,
    • Organizer
      北京大学薬学院富山大学和漢医薬学総合研究所学術交流会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 日本発の植物性医薬品開発に向けたアカデミアでの研究．2018
    • Author(s)
      東田千尋、
    • Organizer
      第 35 回 和漢医薬学会学術大会第 35 回 和漢医薬学会学術大会 公募シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 遠志エキスはアルツハイマー病モデルマウスの軸索変性及び記憶障害の誘発を予防する．2018
    • Author(s)
      久保山友晴、東田千尋、
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgeninによる脳内の軸索修復を介したアルツハイマー病の記憶回復作用．2018
    • Author(s)
      楊熙蒙、東田千尋、
    • Organizer
      第 35 回 和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Development of Promising Therapeutic Drugs for Neurodegenerative Diseases.2018
    • Author(s)
      Chihiro Tohda.
    • Organizer
      4th 2018 Joint Symposium between Institute of Natural Medicine at University of Toyama and Natural Products Research Institute at Seoul National University.
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] HDAC3 inhibition ameliorates memory function via regulating microglial phenotype in Alzheimer’s disease model mice.2018
    • Author(s)
      Kuboyama T, Tohda C.
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-18K07389

  • [Presentation] 神経疾患の治療戦略創出に向けた和漢薬研究．2018
    • Author(s)
      東田千尋、楊熙蒙、
    • Organizer
      第65回日本動物学会総会　企画シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 細胞外ニューロロイキンはアストロサイトからのニューロロイキン分泌を促し、神経細胞の軸索伸展を促す．2018
    • Author(s)
      谷江良崇、田辺紀生、久保山友晴、東田千尋、
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会合同年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アルツハイマー病モデルマウスにおいてHDAC3阻害はマイクログリアのM2化を介して記憶を改善させる．2018
    • Author(s)
      久保山友晴、東田千尋、
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アルツハイマー病の認知機能に及ぼす帰脾湯の効果の研究．2018
    • Author(s)
      渡り英俊　嶋田豊　東田千尋、
    • Organizer
      第 35 回 和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Acteoside-induced PKM2 secretion from skeletal muscle is associated with functional recovery of chronic spinal cord injury.2018
    • Author(s)
      Tohda Chihiro., Kodani Atsushi.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgenin-induced reduction of HSC70 results in axonal regeneration. and improvement of memory function in a mouse model of Alzheimer’s disease2018
    • Author(s)
      Yang Ximeng, Tohda Chihiro.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] マイクログリアのM2/M1比を増加させる遠志による脊髄損傷の改善2018
    • Author(s)
      小湊誠也、久保山友晴、東田千尋、
    • Organizer
      第61回日本神経化学会大会・第40回日本生物学的精神医学会合同年会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Acteoside improves chronic spinal cord injury via a skeletal muscle-secreted new myokine.2017
    • Author(s)
      Kodani A., Tohda C.
    • Organizer
      Society for Neuroscience 47th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 生薬 alkannin と shikonin の A βとタウタンパク凝集阻害と神経細胞死阻害活性：抗アルツハイマー病薬創製に向けて.2017
    • Author(s)
      細井 徹、俵 明里、今田 理裕、東田 千尋、金子 雅幸、藤田 有紀、奥田 充顕、杉本 八郎、小澤 光一郎、西 昭徳、野村 靖幸
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Diosgenin improves memory function in a mouse model of Alzheimer’s disease via the reduction of HSC70.2017
    • Author(s)
      Yang X., Tohda C.
    • Organizer
      第40回日本神経科学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 新規マイオカインを介したアクテオシドによる慢性期脊髄損傷改善作用の研究．2017
    • Author(s)
      小谷篤、東田千尋、
    • Organizer
      日本薬学会北陸支部第129回例会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] DiosgeninによるHSC70の減少はアルツハイマー病の軸索萎縮と記憶障害を改善する2017
    • Author(s)
      楊熙蒙、東田千尋、．
    • Organizer
      日本薬学会北陸支部第129回例会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] エゾウコギ葉水エキスによる記憶向上作用と活性成分の検討2017
    • Author(s)
      山内唯、葛躍偉、吉松嘉代、小松かつ子、東田千尋、
    • Organizer
      第34回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] エゾウコギ葉水エキスによる記憶向上作用と活性成分の検討2017
    • Author(s)
      山内 唯，葛 躍偉，吉松嘉代，小松かつ子，東田千尋
    • Organizer
      第34回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Presentation] Polygalae Radix extract induces M2 microglia and improves the locomotor function in the spinal cord injury.2017
    • Author(s)
      Kominato S, Kuboyama T, Tohda C.
    • Organizer
      International Symposium on Scientific Research of Traditional Medicine.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Neuroleukin enhanced axonal growth in neurons and self secretion from astrocytes.2017
    • Author(s)
      Tohda C., Tanie Y., Tanabe N., Kuboyama T.
    • Organizer
      第40回日本神経科学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 遠志によるアルツハイマー病予防作用．2017
    • Author(s)
      久保山友晴、弘津圭祐、荒井哲也、山﨑寛生、和田篤敬、東田千尋．
    • Organizer
      第34回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Polygalae Radix extract induces M2 microglia predominance and improves spinal cord injury.2017
    • Author(s)
      Kominato S., Kuboyama T., Tohda C.
    • Organizer
      第40回日本神経科学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Cognitive enhancement by diosgenin treatment.2017
    • Author(s)
      Tohda C., Yang X.
    • Organizer
      Society for Neuroscience 47th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Cytosolic aspartate aminotransferase, a direct binding protein of kamikihito, regulates axon growth.2017
    • Author(s)
      Watari H. Shimada Y, Tohda C.
    • Organizer
      The 6th Joint Symposium -WHO CCs for Traditional Medicine in Korea & Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アルツハイマー病の記憶障害を改善する帰脾湯・加味帰脾湯2017
    • Author(s)
      東田千尋
    • Organizer
      第34回和漢医薬学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05276

  • [Presentation] 脊髄損傷の運動麻痺および骨格筋萎縮を改善する薬物の研究．2017
    • Author(s)
      東田千尋、
    • Organizer
      平成29年度中部地区医療・バイオ系シーズ発表会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Novel pharmacological effects of matrine: Axonal growth activity overcoming an inhibitory environment and improvement of spinal cord injury.2017
    • Author(s)
      Tanabe N., Kuboyama T., Tohda C.
    • Organizer
      第40回日本神経科学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] 芍薬エキスおよび芍薬由来化合物の筋細胞に対する効果．2017
    • Author(s)
      金原嘉之、嶋田豊、東田千尋、
    • Organizer
      第34回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Chronic spinal cord injury repair mediated by skeletal muscle-secreted new myokine.2017
    • Author(s)
      Kodani A., Tanabe N., Tohda C.
    • Organizer
      第40回日本神経科学会大会
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] アルツハイマー病の記憶障害を改善する帰脾湯・加味帰脾湯．2017
    • Author(s)
      東田 千尋.
    • Organizer
      第34回和漢医薬学会学術大会 大会特別企画　「日本東洋医学会との合同シンポジウム」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Diosgenin restores axonal degeneration via the reduction of HSC70, resulting in improvement of memory function in Alzheimer’s disease.2017
    • Author(s)
      Yang X., Tohda C.
    • Organizer
      Society for Neuroscience 47th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03558

  • [Presentation] Effects of oleanane-type saponins from the leaves of Eleutherococcus senticosus on axonal outgrowth.2016
    • Author(s)
      葛躍偉、東田千尋、朱妹、吉松嘉代、小松かつ子
    • Organizer
      第33回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2016-08-27
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] アルツハイマー症治療薬開発を指向した Denosomin-Vitamin D3 ハイブリッドの設計と合成2016
    • Author(s)
      村田 賢信, 矢島 久成, 林 祐介, 湊 大志郎, 寺崎 紗有里, 杉本 健士, 東田 千尋, 松谷裕二
    • Organizer
      日本薬学会第１３６年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-25460010

  • [Presentation] 急性期および慢性期脊髄損傷における運動機能へのmatrineの作用．2016
    • Author(s)
      田辺紀生、久保山友晴、東田千尋
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Approach to identify anti-Alzheimer’s disease compounds that are delivered into the brain after administration of traditional medicine.2016
    • Author(s)
      Yang Z, Kuboyama T, Tohda C.
    • Organizer
      Society for Neuroscience 46th Annual Meeting (Neuroscience 2016)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] ヒト胎盤製剤ラエンネックによるアルツハイマー病モデルマウスの記憶障害改善作用．2016
    • Author(s)
      東田千尋、小暮智里
    • Organizer
      第5回JBP研究会
    • Place of Presentation
      久留米
    • Year and Date
      2016-09-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] The human placenta-derived drug, Laennec, improves cognitive dysfunction in a mouse model of Alzheimer’s disease.2016
    • Author(s)
      Tohda C, Kogure C.
    • Organizer
      Society for Neuroscience 46th Annual Meeting (Neuroscience 2016)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] アルツハイマー病治療を目指した伝統薬物研究．2016
    • Author(s)
      久保山友晴，楊志友，東田千尋
    • Organizer
      日本薬学会北陸支部会128回例会
    • Place of Presentation
      金沢
    • Year and Date
      2016-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Presentation] アルツハイマー病治療を目指した伝統薬物研究.2016
    • Author(s)
      久保山友晴、楊志友、東田千尋
    • Organizer
      日本薬学会北陸支部会128回例会
    • Place of Presentation
      金沢
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Extracellular vimentin is a novel axonal growth facilitator for functional recovery in spinal cord-injured mice.2016
    • Author(s)
      Shigyo M, Tohda C.
    • Organizer
      Society for Neuroscience 46th Annual Meeting (Neuroscience 2016)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Effects of oleanane-type saponins from the leaves of Eleutherococcus senticosus on axonal outgrowth.2016
    • Author(s)
      葛躍偉，東田千尋，Zhu S.，吉松嘉代，小松かつ子
    • Organizer
      第33回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2016-08-27
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Presentation] マイクログリアの良性化活性を有する生薬の探索.2016
    • Author(s)
      小湊誠也、久保山友晴、東田千尋
    • Organizer
      日本薬学会北陸支部会128回例会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] ヒト胎盤製剤ラエンネックによるアルツハイマー病モデルマウスの記憶障害改善作用．2016
    • Author(s)
      東田千尋、小暮智里
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Diosgeninによるアルツハイマー病の記憶回復にHSC70の減少が関与する．2016
    • Author(s)
      楊熙蒙、久保山友晴、東田千尋
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] 加味帰脾湯はcytosolic aspartate aminotransferaseの活性化を介して軸索伸展を制御する．2016
    • Author(s)
      小林諒、渡り英俊、嶋田豊、東田千尋
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] 生薬エキス投与後に脳内で検出される成分の同定とそのアルツハイマー病改善メカニズムの解析.2016
    • Author(s)
      東田千尋,、楊志友、久保山友晴
    • Organizer
      第21回天然薬物の開発と応用シンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2016-10-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Reduction of HSC70 relates to diosgenin-induced memory improvement in a mouse model of Alzheimer’s disease.2016
    • Author(s)
      Yang X, Kuboyama T, Tohda C.
    • Organizer
      Society for Neuroscience 46th Annual Meeting (Neuroscience 2016)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Naringenin restores axonal degeneration and memory deficits in a mouse model of Alzheimer’s disease.2016
    • Author(s)
      Yang Z, Kuboyama T, Tohda C.
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] 生薬エキス投与後に脳内で検出される成分の同定とそのアルツハイマー病改善メカニズムの解析．2016
    • Author(s)
      東田千尋，楊志友，久保山友晴
    • Organizer
      第21回天然薬物の開発と応用シンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2016-10-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Presentation] 神経変性疾患の新しい治療戦略に関する研究2016
    • Author(s)
      東田千尋
    • Organizer
      平成28年度 日本薬学会学術振興賞受賞講演
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Kamikihito regulates axonal growth via cytosolic aspartate aminotransferase activation.2016
    • Author(s)
      Kobayashi R, Watari H, Shimada Y, Tohda C.
    • Organizer
      Society for Neuroscience 46th Annual Meeting (Neuroscience 2016)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] 細胞外neuroleukinは脊髄損傷の運動機能障害を回復させる．2016
    • Author(s)
      谷江良崇、田辺紀生、久保山友晴、東田千尋
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Oleanane-type triterpene saponins from the leaves of Eleutherococcus senticosus restores Aβ25-35 induced neurite degeneration2016
    • Author(s)
      小松かつ子，Yuewei GE，東田千尋，Shu ZHU，吉松嘉代
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Presentation] Approach to identify anti-Alzheimer’s disease compounds that are delivered into the brain after administration of traditional medicine.2016
    • Author(s)
      Yang Z., Kuboyama T., Tohda C.
    • Organizer
      Society for Neuroscience 46th Annual Meeting (Neuroscience 2016)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Presentation] ヒト胎盤製剤ラエンネックによるアルツハイマー病モデルマウスの記憶障害改善作用とメカニズムの解析.2016
    • Author(s)
      東田千尋、小暮智里.
    • Organizer
      日本生薬学会第63回年会
    • Place of Presentation
      富山
    • Year and Date
      2016-09-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] 骨格筋を活性化することにより慢性期脊髄損傷を改善する薬物の研究．2016
    • Author(s)
      小谷篤、田辺紀生、久保山友晴、東田千尋
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Comparing the effects of kamikihito in Japan and Kami-Guibi-Tang in Korea on memory enhancement: working towards the development of a global study.2016
    • Author(s)
      Watari H, Tohda M, , Cho K-H, Kyung P-S, Jung W-S, Shimada Y, Tohda C.
    • Organizer
      The 5th Joint Symposium-WHO CCs for Traditional Medicine in Japan & Korea “Integration and Modernization of Traditional Medicine”
    • Place of Presentation
      Korea
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Naringenin restores axonal degeneration and memory deficits in a mouse model of Alzheimer’s disease.2016
    • Author(s)
      Yang Z., Kuboyama T., Tohda C.
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Presentation] 和漢薬による神経変性疾患の改善作用の解析－病気を治す分子を見出すアプローチ―2016
    • Author(s)
      東田千尋
    • Organizer
      日本薬学会第136年会シンポジウム「和漢薬の科学基盤：新たな創薬方法論と疾病治療戦略の創生を目指して」
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Matrine facilitates axonal growth and improves motor function in spinal cord injury in acute and chronic phases.2016
    • Author(s)
      Tanabe N, Kuboyama T, Tohda C.
    • Organizer
      Society for Neuroscience 46th Annual Meeting (Neuroscience 2016)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Extracellular neuroleukin improves hindlimb motor dysfunction of spinal cord injury.2016
    • Author(s)
      Tanie Y, Tanabe N, Kuboyama T, Tohda C.
    • Organizer
      Society for Neuroscience 46th Annual Meeting (Neuroscience 2016)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] アルツハイマー治療薬開発を指向したDenosomin-Vitamin D3ハイブリッドの設計と合成．2015
    • Author(s)
      村田賢信、矢島久成、杉本健士、湊大志郎、東田千尋、松谷裕二
    • Organizer
      フォーラム富山「創薬」
    • Place of Presentation
      富山
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] 伝統薬物研究が拓く認知症の根本治療戦略．2015
    • Author(s)
      東田千尋、渡り英俊、久保山友晴
    • Organizer
      医療薬学フォーラム2015 第23回クリニカルファーマシーシンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2015-07-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Extracellular virnentin interacts with insulin-like growth factor l receptor to promote axonal growth.2015
    • Author(s)
      Shigyo M. Kuboyama T. Sawai Y, Tada-Umezaki M, Tohda C.
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Immediate or delayed administrations of matrine improve motor dysfunction in spinal cord injured mice.2015
    • Author(s)
      Tanabe N, Kuboyama T, Kazuma K, Konno K, Tohda C.
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] アルツハイマー型認知症モデルマウスの認知機能に対するヤムズゲニン含有トゲドコロ末の効果.2015
    • Author(s)
      大野木宏、速水祥子、工藤庸子、安井まどか、東田千尋.
    • Organizer
      第15回日本抗加齢医学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2015-05-29
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] ヒト胎盤エキスによるアルツハイマー病モデルマウスの記憶障害改善作用.2015
    • Author(s)
      小暮智里、東田千尋.
    • Organizer
      第32回和漢医薬学会学術大会
    • Place of Presentation
      富山
    • Year and Date
      2015-08-22
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] 伝統薬物-based創薬によるアルツハイマー病の治療戦略．2015
    • Author(s)
      東田千尋
    • Organizer
      第133回日本薬理学会関東部会ミニシンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2015-10-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] アストロサイトから分泌されるvimentinを介した脊髄損傷作用メカニズムの解明．2015
    • Author(s)
      執行美智子、東田千尋
    • Organizer
      第50回日本脊髄障害医学会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Design, synthesis, and biological evaluation of promising anti-Alzheimer’s compounds having dihydropyrone unit as a key component.2015
    • Author(s)
      Sugimoto K, Yajima H, Tohda C, Matsuya Y.
    • Organizer
      The XVI International Conference on Heterocycles in Bioorganic Chemistry
    • Place of Presentation
      Metz (France)
    • Year and Date
      2015-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460010

  • [Presentation] 苦参およびその含有成分matrineは軸索伸展を促進し、脊髄損傷マウスの運動機能不全を改善する.2015
    • Author(s)
      田辺紀生、東田千尋
    • Organizer
      第50回日本脊髄障害医学会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Brain-Active Herbal Metabolites for the Treatment of Alzheimer’s Disease2015
    • Author(s)
      Yang Z., Kuboyama T., Tohda C.
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Presentation] 細胞外vimentinによる軸索伸展作用メカニズムの解明．2015
    • Author(s)
      執行美智子、久保山友晴、梅嵜雅人、沢井裕佑、東田千尋
    • Organizer
      日本薬学会北陸支部第127回例会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-15
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] The mechanism of Denosomin in astrocytes leading to release of axonal growth factors.2015
    • Author(s)
      Tanie Y, Shigyo M, Tanabe N, Kuboyama T, Tohda C.
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] 神経変性疾患治療のイノベーションを目指した漢方研究.2015
    • Author(s)
      東田千尋
    • Organizer
      第66回日本東洋医学会学術総会　シンポジウム「漢方研究の新たな展開」
    • Place of Presentation
      富山
    • Year and Date
      2015-06-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Crude drug-derived brain-active constituents for improvement of Alzheimer’s disease.2015
    • Author(s)
      Yang Z, Kuboyama T, Tohda C.
    • Organizer
      第32回和漢医薬学会学術大会
    • Place of Presentation
      富山
    • Year and Date
      2015-08-22
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Brain-Active Herbal Metabolites for the Treatment of Alzheimer’s Disease.2015
    • Author(s)
      Yang Z, Kuboyama T, Tohda C.
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Diosgeninによるアルツハイマー病の記憶回復に関わるシグナル分子の探索.2015
    • Author(s)
      楊熙蒙、久保山友晴、東田千尋.
    • Organizer
      第32回和漢医薬学会学術大会
    • Place of Presentation
      富山
    • Year and Date
      2015-08-22
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF PROMISING ANTI-ALZHEIMER’S COMPOUNDS HAVING DIHYDROPYRONE UNIT AS A KEY COMPONENT.2015
    • Author(s)
      Sugimoto K, Yajima H, Tohda C, Matsuya Y.
    • Organizer
      XVI International Conference on Heterocycles in Bioorganic Chemistry (Bioheterocycles 2015)
    • Place of Presentation
      Metz, France
    • Year and Date
      2015-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Crude drug-derived brain-active constituents for improvement of Alzheimer’s disease2015
    • Author(s)
      Yang Z., Kuboyama T., Tohda C.
    • Organizer
      第32回和漢医薬学会学術大会
    • Place of Presentation
      富山
    • Year and Date
      2015-08-23
    • Data Source
      KAKENHI-PROJECT-15H05268

  • [Presentation] Diosgenin decreases the expression of HSC70 and improves memory function in Alzheier’s disease model mice.2015
    • Author(s)
      Yang X, Kuboyama T, Tohda C.
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Cytosolic asparatate aminotransferase relates to axonal growth control under Aβ treatment.2015
    • Author(s)
      Kobayashi R, Watari H, Shimada Y, Tohda C.
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] A novel compound, denosomin, ameliorates motor function in spinal cord injured mice via axonal growth associated with astrocyte-secreted vimentin.2015
    • Author(s)
      Kuboyama T., Shigyo M., Tohda C.
    • Organizer
      JMSA New York Life Science Forum 2015
    • Place of Presentation
      New York, USA
    • Year and Date
      2015-04-12
    • Data Source
      KAKENHI-PROJECT-26670044

  • [Presentation] Improvement of memory function by traditional medicine in Alzheimer’s disease model mice2014
    • Author(s)
      東田千尋
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] Improvement of memory function by traditional medicine in Alzheimer's disease model mice2014
    • Author(s)
      東田千尋
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Improvement of memory function by traditional medicine in Alzheimer’s disease model mice．2014
    • Author(s)
      東田千尋
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 脊髄損傷の運動機能改善効果を持つ漢方生薬の研究2013
    • Author(s)
      田辺紀生，久保山友晴，数馬恒平，紺野勝弘，東田千尋
    • Organizer
      第30回和漢医薬学会学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] 新規神経系賦活薬創成を目指したデノソミン-Vitamin D3ハイブリッドの合成2013
    • Author(s)
      矢島久成，杉本健士，東田千尋，湊大志郎，松谷裕二
    • Organizer
      有機合成化学北陸セミナー
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-25460010

  • [Presentation] A novel compound, Denosomin, promotes axonal growth via astrocytes secreting vimentin after spinal cord injury．2013
    • Author(s)
      Shigyo M, Teshigawara K, Kuboyama T, Nagata A, Sugimoto K, Matsuya Y, Tohda C.
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 加味帰脾湯のtauリン酸化持続抑制によるアルツハイマー病改善作用2013
    • Author(s)
      渡り英俊，嶋田豊，東田千尋
    • Organizer
      第30回和漢医薬学会学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] Investigation of crude drugs effective for spinal cord injured mice2013
    • Author(s)
      Tanabe N, Kuboyama T, Miyanaga S, Kazuma K, Konno K, Tohda C
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Diosgeninによるアルツハイマー病モデルマウスの記憶改善作用とその分子メカニズム2013
    • Author(s)
      東田千尋
    • Organizer
      第3回和漢研・長崎熱帯研ジョイントセミナー
    • Place of Presentation
      長崎大学(長崎)(招待講演)
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] Diosgenin is an exogenous activator of 1,25D3-MARRS (Pdia3/ERp57) and improves memory dysfunction and axonal degeneration in Alzheimer’s disease model 5XFAD mice2013
    • Author(s)
      Tohda C., Urano T., Umezaki M., Kuboyama T.
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] 新規化合物denosomin はアストロサイトからのvimentin 放出を促進して脊髄損傷マウスの運動機能を改善させる2013
    • Author(s)
      久保山友晴, 執行美智子, 東田千尋
    • Organizer
      平成25年度神経糖鎖生物学夏の班会議
    • Place of Presentation
      滋賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 新規化合物denosominはアストロサイトからのvimentin放出を促進して脊髄損傷マウスの運動機能を改善させる．2013
    • Author(s)
      久保山友晴、執行美智子、東田千尋.
    • Organizer
      平成25年度神経糖鎖生物学夏の班会議
    • Place of Presentation
      滋賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] デノソミン-VD3 ハイブリッドの設計と合成を基盤とした新規アルツハイマー治療薬の開発研究2013
    • Author(s)
      矢島久成, 杉本健士, 湊大志郎, 東田千尋, 松谷裕二
    • Organizer
      複素環化学討論会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Endocytosis-mediated axonal growth cone degeneration induced by amyloid β2013
    • Author(s)
      Kuboyama T, Nishiko H, Tohda C
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 「神経細胞の一部を再生させることによる脊髄損傷の運動機能改善」に向けて2013
    • Author(s)
      東田千尋
    • Organizer
      平成25年度全国脊髄損傷者連合会総会第12回富山大会
    • Place of Presentation
      砺波
    • Year and Date
      2013-06-08
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] NMDA誘発の持続的神経細胞損傷に対する内在性AChの抑制効果：PKC-VEGF系の関与2013
    • Author(s)
      稲田千香子, Le Thi Xoan, 藤原博典, 東田道久, 松本欣三
    • Organizer
      第64回日本薬理学会北部会
    • Place of Presentation
      旭川
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 脊髄損傷後の機能回復に低分子量タンパク質Racが関与する．2013
    • Author(s)
      甲田将章、上山健彦、執行美智子、久保山友晴、東田千尋、齋藤尚亮、甲村英二.
    • Organizer
      日本脳神経外科学会　第72回学術総会,
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 黄蓍による small RNA 発現変化と、その変化が 5-HT2CR mRNA 上に及ぼす影響2013
    • Author(s)
      東田道久
    • Organizer
      第30回和漢医薬学会大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 脊髄損傷後の機能回復に低分子量タンパク質Rac が関与する2013
    • Author(s)
      甲田将章, 上山健彦, 執行美智子, 久保山友晴, 東田千尋, 齋藤尚亮, 甲村英二
    • Organizer
      日本脳神経外科学会 第72回学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Investigation of crude drugs effective for spinal cord injured mice．2013
    • Author(s)
      Tanabe N, Kuboyama T, Miyanaga S, Kazuma K, Konno K, Tohda C.
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 「伝統薬物データベース」の構築(3)2013
    • Author(s)
      柴原直利, 条美智子, 小松かつ子, Zhu Shu, 門脇真, 山本武, 東田千尋, 紺野勝弘, 数馬恒平
    • Organizer
      第30回和漢医薬学会学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 加味帰脾湯のtauリン酸化持続抑制によるアルツハイマー病改善作用．2013
    • Author(s)
      渡り英俊　嶋田豊　東田千尋．
    • Organizer
      第30回和漢医薬学会学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] A novel compound, Denosomin, promotes axonal growth via astrocytes secreting vimentin after spinal cord injury2013
    • Author(s)
      Shigyo M., Teshigawara K., Kuboyama T., Nagata A., Sugimoto K., Matsuya Y., Tohda C.
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] Ashwagandha成分Sominoneの誘導体Denosominのアストロサイトを介した脊髄損傷改善作用．2013
    • Author(s)
      執行美智子、久保山友晴、東田千尋.
    • Organizer
      第30回和漢医薬学会学術大会,
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 脊髄損傷の運動機能改善効果を持つ漢方生薬の研究2013
    • Author(s)
      田辺紀生, 久保山友晴, 数馬恒平, 紺野勝弘, 東田千尋
    • Organizer
      第30回和漢医薬学会学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 新規アルツハイマー治療薬創製を目指したデノソミンーVD3ハイブリッドの設計と合成．2013
    • Author(s)
      矢島久成、杉本健士、湊大志郎、東田千尋、松谷裕二
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Endocytosis-mediated axonal growth cone degeneration induced by amyloid β2013
    • Author(s)
      Kuboyama T., Nishiko H., Tohda C.
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] アルツハイマー病を改善する和漢薬2013
    • Author(s)
      東田千尋
    • Organizer
      第31回湯本求眞学術講演会
    • Place of Presentation
      金沢
    • Year and Date
      2013-07-28
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Ashwagandha 成分Sominone の誘導体Denosomin のアストロサイトを介した脊髄損傷改善作用2013
    • Author(s)
      執行美智子, 久保山友晴, 東田千尋
    • Organizer
      第30回和漢医薬学会学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Investigation of crude drugs effective for spinal cord injured mice2013
    • Author(s)
      Tanabe N., Kuboyama T., Miyanaga S., Kazuma K., Konno K., Tohda C.
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] 伝統薬物をベースとしたアカデミア創薬．2013
    • Author(s)
      東田千尋
    • Organizer
      第3回和漢研・がん研ジョイントセミナー　アカデミア創薬の心・技・体
    • Place of Presentation
      金沢
    • Invited
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 「伝統薬物データベース」の構築（３）2013
    • Author(s)
      柴原直利、条美智子、小松かつ子、Zhu Shu、門脇真、山本武、東田千尋、紺野勝弘、数馬恒平
    • Organizer
      第30回和漢医薬学会学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] A novel compound, Denosomin, promotes axonal growth via astrocytes secreting vimentin after spinal cord injury2013
    • Author(s)
      Shigyo M, Teshigawara K, Kuboyama T, Nagata A, Sugimoto K, Matsuya Y, Tohda C
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 伝統薬物をベースとしたアカデミア創薬2013
    • Author(s)
      東田千尋
    • Organizer
      第3回和漢研・がん研ジョイントセミナー アカデミア創薬の心・技・体
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] デノソミン－VD3ハイブリッドの設計と合成を基盤とした新規アルツハイマー治療薬の開発研究2013
    • Author(s)
      矢島久成，杉本健士，湊大志郎，東田千尋，松谷裕二
    • Organizer
      第43回複素環化学討論会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-25460010

  • [Presentation] 新規アルツハイマー治療薬創製を目指したデノソミン-VD3 ハイブリッドの設計と合成2013
    • Author(s)
      矢島久成, 杉本健士, 湊大志郎, 東田千尋, 松谷裕二
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Diosgenin is an exogenous activator of 1,25D3-MARRS (Pdia3/ERp57) and improves memory dysfunction and axonal degeneration in Alzheimer’s disease model 5XFAD mice．2013
    • Author(s)
      Tohda C, Urano T, Umezaki M, Kuboyama T.
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] デノソミン-VD3ハイブリッドの設計と合成を基盤とした新規アルツハイマー治療薬の開発研究．2013
    • Author(s)
      矢島久成、杉本健士、湊大志郎、東田千尋、松谷裕二.
    • Organizer
      複素環化学討論会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Endocytosis-mediated axonal growth cone degeneration induced by amyloid β.2013
    • Author(s)
      Kuboyama T, Nishiko H, Tohda C.
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Diosgenin is an exogenous activator of 1, 25D3-MARRS (Pdia3/ERp57) and improves memory dysfunction and axonal degeneration in Alzheimer's disease model 5XFAD mice2013
    • Author(s)
      Tohda C, Urano T, Umezaki M, Kuboyama T
    • Organizer
      Neuro 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 加味帰脾湯のtau リン酸化持続抑制によるアルツハイマー病改善作用2013
    • Author(s)
      渡り英俊 嶋田豊 東田千尋
    • Organizer
      第30回和漢医薬学会学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 伝統薬物をベースとしたアカデミア創薬2013
    • Author(s)
      東田千尋
    • Organizer
      第3回和漢研・がん研ジョイントセミナー「アカデミア創薬の心・技・体」
    • Place of Presentation
      金沢エクセルホテル東急(金沢)(招待講演)
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] Ashwagandha成分Sominoneの誘導体Denosominのアストロサイトを介した脊髄損傷改善作用2013
    • Author(s)
      執行美智子，久保山友晴，東田千尋
    • Organizer
      第30回和漢医薬学会学術大会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] 「伝統薬物データベース」の構築(2)2012
    • Author(s)
      柴原直利, 小松かつ子, Zhu Shu, 山本武, 門脇真, 松永智子, 東田千尋, 宮永賢, 数馬恒平, 紺野勝弘
    • Organizer
      第29回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 阻害性プロテオグリカンによる軸索再生阻害機構の解明2012
    • Author(s)
      久保山友晴, Vance Lemmon, Jerry Silver, 東田千尋, 上口裕之
    • Organizer
      2012年度包括脳ネットワーク夏のワークショップ
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Diosgenin によるアルツハイマー病モデルマウスの記憶改善作用とその分子メカニズム2012
    • Author(s)
      東田千尋
    • Organizer
      富山大学和漢医薬学総合研究所・長崎大学熱帯医学研究所第3回交流セミナー
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] アルツハイマー病モデルマウスを用いたEleutheroside BおよびEleutheroside Eの記憶改善効果の検討2012
    • Author(s)
      松永智子、東田千尋、白焱晶、朱姝、小松かつ子
    • Organizer
      第29回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Possible involvement of PKC&#61537; activation and gliosis suppression in rescuing effect of tactrine on NMDA- induced cell damage in organotypic hippocampal slice cultures2012
    • Author(s)
      Le Thi, X., Inada, C., Matsumoto, K., Fujiwara, H. and Tohda, M
    • Organizer
      第63回日本薬理学会北部会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] Diosgeninによるアルツハイマー病モデルマウスの記憶改善作用とその分子メカニズム．2012
    • Author(s)
      東田千尋
    • Organizer
      富山大学和漢医薬学総合研究所・長崎大学熱帯医学研究所第3回交流セミナー
    • Place of Presentation
      長崎
    • Invited
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Diosgenin is an exogenous activator of 1,25D3-MARRS (Pdia3/ERp57) and improves memory dysfunction and axonal degeneration in Alzheimer’s disease model 5XFAD mice.2012
    • Author(s)
      Tohda C, Urano T, Umezaki M, Nemere I, Kuboyama T
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] A novel compound, Denosomin induces vimentin-secretion from astrocytes, resulting in promotion of axon elongation2012
    • Author(s)
      Kuboyama T., Teshigawara K., Shigyo M., Sugimoto K., Matsuya Y., Tohda C.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] Denosomin improves SCI via axonal growth by increasing astrocyte-secreted vimentin.2012
    • Author(s)
      Shigyo M, Kuboyama T, Teshigawara K, Sugimoto K, Matsuya Y, Tohda C
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Diosgenin is an exogenous activator of 1,25D3-MARRS (Pdia3/ERp57) and improves memory dysfunction and axonal degeneration in Alzheimer's disease model 5XFAD mice2012
    • Author(s)
      Tohda C., Urano T., Umezaki M., Nemere I., Kuboyama T.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] A novel compound, Denosomin induces vimentin-secretion from astrocytes, resulting in promotion of axon elongation.2012
    • Author(s)
      Kuboyama T, Teshigawara K, Shigyo M, Sugimoto K, Matsuya Y, Tohda C
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Natural medicine study aiming to explore therapeutic strategies for neurodegenerative diseases2012
    • Author(s)
      Tohda C
    • Organizer
      International Symposium on Biomedicine and Drug-Development. Nanotechnology : from Bench to Enduser
    • Place of Presentation
      Basel, Switzerland
    • Year and Date
      2012-09-25
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Denosomin improves SCI via axonal growth by increasing astrocyte-secreted vimentin2012
    • Author(s)
      Shigyo M, Kuboyama T, Teshigawara K, Sugimoto K, Matsuya Y, Tohda C
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 和漢薬理論でうつ病の基礎研究に切り込む：うつ病の細分化、分子機序の解明、新規治療薬の開発をめざして2012
    • Author(s)
      東田道久
    • Organizer
      第15回天然薬物研究方法論アカデミー
    • Place of Presentation
      千葉
    • Invited
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] Diosgenin is an exogenous activator of 1,25D_3-MARRS (Pdia3/ERp57) and improves memory dysfunction and axonal degeneration in Alzheimer's disease model 5XFAD mice2012
    • Author(s)
      Tohda C, Urano T, Umezaki M, Nemere I, Kuboyama T
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 量子化学的計算による人参薬効成分: Ginsenoside 類などの薬効機構の解明．2012
    • Author(s)
      梅嵜雅人、杉本佳奈子、春木孝之、伊藤泰地、武田湧、兼松佑典、東田千尋、北幸海、立川仁典
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Natural medicine study aiming to explore therapeutic strategies for neurodegenerative diseases2012
    • Author(s)
      Tohda C
    • Organizer
      21st Symposium on Dementia
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2012-04-15
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 特別シンポジウム　薬学系女性の研究キャリア形成　～アカデミア・企業・世界を舞台に2012
    • Author(s)
      東田千尋
    • Organizer
      日本薬学会第132年会(招待講演)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] アルツハイマー病モデルマウスを用いたEleutheroside B およびEleutheroside Eの記憶改善効果の検討2012
    • Author(s)
      松永智子, 東田千尋, 白焱晶, 朱姝, 小松かつ子
    • Organizer
      第29回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Natural medicine study aiming to explore therapeutic strategies for neurodegenerative diseases.2012
    • Author(s)
      Tohda C.
    • Organizer
      21st Symposium on Dementia
    • Place of Presentation
      Seoul, Korea(招待講演)
    • Year and Date
      2012-04-15
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] Natural medicine study aiming to explore therapeutic strategies for neurodegenerative diseases2012
    • Author(s)
      Tohda C.
    • Organizer
      International Symposium on Biomedicine and Drug-Development. Nanotechnology : from Bench to Enduser
    • Place of Presentation
      Basel, Switzerland(招待講演)
    • Year and Date
      2012-09-25
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] 薬学系女性の研究キャリア形成 ~アカデミア・企業・世界を舞台に2012
    • Author(s)
      東田千尋
    • Organizer
      第54回日本薬学会第132年会特別シンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-31
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] ヒトおよびうつ病動物を用いた補中益気湯脳内応答性のMRIによる解析:薬物感受性による違い2012
    • Author(s)
      東田道久, 他計5名
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] Novel mechanism of functional recovery from spinal cord injury.2012
    • Author(s)
      Tohda C., Kuboyama T., Teshigawara K., Shigyo M.
    • Organizer
      14th International Congress of Histochemistry and Cytochemistry
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 和漢薬はうつ病を知っている！：和漢薬概念によりうつ病の細分化と治療戦略を考える2012
    • Author(s)
      東田道久
    • Organizer
      第17回富山大学和漢医薬学総合研究所夏期セミナー
    • Place of Presentation
      富山
    • Invited
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 量子化学的計算による人参薬効成分 : Ginsenoside 類などの薬効機構の解明2012
    • Author(s)
      梅嵜雅人, 杉本佳奈子, 春木孝之, 伊藤泰地, 武田湧, 兼松佑典, 東田千尋, 北幸海, 立川仁典
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Denosomin improves SCI via axonal growth by increasing astrocyte-secreted Vimentin2012
    • Author(s)
      Shigyo M., Kuboyama T., Teshigawara K., Sugimoto K., Matsuya Y., Tohda C.
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] Effect of Thunbergia laurifolia on cognitive and emotional deficits in olfactolectomized mice2012
    • Author(s)
      Piyanuch, R., Pongtip, S., 田中謙, 松本欣三, 東田道久
    • Organizer
      第29回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 阻害性プロテオグリカンによる軸索再生阻害機構の解明．2012
    • Author(s)
      久保山友晴、Vance Lemmon、Jerry Silver、東田千尋、上口裕之
    • Organizer
      2012年度包括脳ネットワーク夏のワークショップ.
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Novel mechanism of functional recovery from spinal cord injury2012
    • Author(s)
      Tohda C, Kuboyama T, Teshigawara K, Shigyo M
    • Organizer
      14th International Congress of Histochemistry and Cytochemistry
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] アルツハイマー病マウスを用いたEleutheroside B及びEleutheroside Eの記憶改善効果の検討2012
    • Author(s)
      松永智子,東田千尋,白〓晶,朱妹,小松かつ子
    • Organizer
      第29回和漢医薬学会学術大会
    • Place of Presentation
      北里大学薬学部(東京)
    • Data Source
      KAKENHI-PROJECT-24406005

  • [Presentation] A novel compound, Denosomin induces vimentin-secretion from astrocytes, resulting in promotion of axon elongation2012
    • Author(s)
      Kuboyama T, Teshigawara K, Shigyo M, Sugimoto K, Matsuya Y, Tohda C
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 「伝統薬物データベース」の構築（２）2012
    • Author(s)
      柴原直利、小松かつ子、Zhu Shu、山本武、門脇真、松永智子、東田千尋、宮永賢、数馬恒平、紺野勝弘
    • Organizer
      第29回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Searching for natural medicines that improve spinal cord injury2011
    • Author(s)
      Wang XH, Kuboyama T, Miyanaga S, Kazuma K, Konno K, Satake M, Tohda C
    • Organizer
      第28回和漢医薬学会学術大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] アルツハイマー病モデルマウスの記憶障害と軸索変性を改善する加味帰脾湯の作用2011
    • Author(s)
      中田理恵, 東田千尋
    • Organizer
      第28回和漢医薬学会学術大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 補中益気湯の抗うつ及び消化器系活性化作用に関する検討:抗うつ薬との違いについて2011
    • Author(s)
      東田道久, 他計4名
    • Organizer
      第62回日本薬理学会北部会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 新規化合物1-deoxy-nor-sominone (Denosomin)によるアストロサイトを介した脊髄損傷の改善作用2011
    • Author(s)
      勅使川原匡, 久保山友晴, 松谷裕二, 東田千尋
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Genetic, chemical and pharmacological diversity of Ginseng drugs2011
    • Author(s)
      Komatsu K., Zhu S., Tohda C.
    • Organizer
      The 6th JSP-CCTCNM-KSP International Conference on Pharmacognosy
    • Place of Presentation
      Shengyang Pharmaceutical Univ. (Shengyang, China)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21406004

  • [Presentation] アルツハイマー病モデルマウスの記憶障害と軸索変性に対する加味帰脾湯の改善作用2011
    • Author(s)
      中田理恵, 久保山友晴, 東田千尋
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 神経化学の若手研究者育成セミナー　「神経変性疾患を知る・克服する 」2011
    • Author(s)
      東田千尋
    • Organizer
      東田千尋
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Participation of BNIP-3 in anti-depressive action : BNIP-3 participates in not only the cell death/survival but also neuronal activity2011
    • Author(s)
      Kanzaki M., Tohda M
    • Organizer
      第41回北米神経科学会
    • Place of Presentation
      ワシントンDC
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 和漢薬の理論を基盤にした各種うつ病発症機序の分類・解明と作用薬の開発をめざして2011
    • Author(s)
      東田道久
    • Organizer
      第28回和漢医薬学会
    • Place of Presentation
      富山(招待講演)
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] アルツハイマー病モデルマウスの記憶障害と軸索変性に対する加味帰脾湯の改善作用．2011
    • Author(s)
      中田理恵、久保山友晴、東田千尋
    • Organizer
      東田千尋会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] コンドロイチン硫酸プロテオグリカンによる軸索再生阻害のシグナル伝達機構．2011
    • Author(s)
      久保山友晴，Jerry Silver，東田千尋, 上口裕之
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 脊髄損傷の運動機能回復に関与するDenosomin の軸索伸展作用2011
    • Author(s)
      執行美智子, 長田愛子, 勅使川原匡, 久保山友晴, 松谷裕二, 東田千尋
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 脊髄損傷の運動機能回復に関与するDenosominの軸索伸展作用．2011
    • Author(s)
      執行美智子，長田愛子，勅使川原匡，久保山友晴，松谷裕二，東田千尋
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 「伝統医薬データベース」の構築2011
    • Author(s)
      柴原直利, 東田千尋, 朱〓, 櫻井宏明, 数馬恒平, 山本武, 小泉桂一, 紺野勝弘, 門脇真, 小松かつ子
    • Organizer
      第28回和漢医薬学会学術大会
    • Place of Presentation
      富山県民会館(富山)
    • Data Source
      KAKENHI-PROJECT-21406004

  • [Presentation] Genetic, chemical and pharmacological diversity of Ginseng drugs2011
    • Author(s)
      Komatsu K, Zhu S, Tohda C
    • Organizer
      The 6th CCTNM-KSP-JSP Joint Symposium on Pharmacognosy
    • Place of Presentation
      Shenyang, China
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 「伝統医薬データベース」の構築2011
    • Author(s)
      柴原直利, 東田千尋, Zhu Shu, 櫻井宏明, 数馬恒平, 山本武, 小泉桂一, 紺野勝弘, 門脇真, 小松かつ子
    • Organizer
      第28回和漢医薬学会学術大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] コンドロイチン硫酸プロテオグリカンによる軸索再生阻害のシグナル伝達機構2011
    • Author(s)
      久保山友晴, Jerry Silver, 東田千尋, 上口裕之
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] 新規化合物1-deoxy-nor-sominone (Denosomin)2011
    • Author(s)
      勅使川原匡，久保山友晴，松谷裕二，東田千尋
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Genetic, chemical and pharmacological2011
    • Author(s)
      Komatsu K, Zhu S, Tohda C：
    • Organizer
      The 6th CCTNM-KSP-JSP Joint Symposium(招待講演)
    • Place of Presentation
      Shenyang, China
    • Data Source
      KAKENHI-PROJECT-23500439

  • [Presentation] Participation of BNIP-3 in anti-depressive action : BNIP-3 participates in not only the cell death/survival but also neuronal activity2011
    • Author(s)
      Kanzaki M. and Tohda M
    • Organizer
      第41回北米神経科学会
    • Place of Presentation
      米国, ワシントンDC
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 補中益気湯によるうつ病関連分子の探索と作用機序解明2010
    • Author(s)
      東田道久
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] うつ病に立ち向かう和漢薬2010
    • Author(s)
      東田道久
    • Organizer
      初心者にもわかる和漢薬一日セミナー
    • Place of Presentation
      富山
    • Year and Date
      2010-01-30
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] Active components of Siberian ginseng for protection of amyloidβ(25-35)-induced neuritic atrophy in cultured cortical neurons2010
    • Author(s)
      Bai Y. J., Zhu S., Tohda C., Komatsu K.
    • Organizer
      日本薬学会北陸支部第122回例会
    • Place of Presentation
      金沢
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-21406004

  • [Presentation] Effect of Acori Graminei Rhizoma on Aβ(25-35)-induced atrophies of axons and dendrites2010
    • Author(s)
      Bai Y. J., Zhu S., Tohda C., Komatsu K.
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-21406004

  • [Presentation] γ-Mangostin as an antidepressant drug : evaluation by the in vitro assay systems highly responsive to antidepressant2010
    • Author(s)
      Tohda M., 他計3名
    • Organizer
      The 9th JSPS-NRCT Joint Semina
    • Place of Presentation
      バンコック
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 和漢処方によるBNIP-3 mRNA発現上昇と抗うつ作用との関連性に関する検討2010
    • Author(s)
      東田道久、松本欣三
    • Organizer
      第27回和漢医薬学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] ラット大脳皮質初代培養細胞の培養日数に伴う各種mRNA発現量変化とそれへの5-HT2CR RNA editingの影響2010
    • Author(s)
      東田道久、松本欣三
    • Organizer
      第61回日本薬理学会北部会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] Active components of Siberian ginseng for protection of amyloid β (25-35)-induced neuritic atrophy in cultured cortical neurons2010
    • Author(s)
      Bai Y.J., Zhu S., Tohda C., Komatsu K.
    • Organizer
      日本薬学会北陸支部第122回例会
    • Place of Presentation
      北陸大学薬学部(金沢)
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-21406004

  • [Presentation] 和漢薬はうつ病の救世主になりえるか2010
    • Author(s)
      東田道久
    • Organizer
      第15回和漢医薬学総合研究所夏期セミナー
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 和漢処方によるBNIP-3 mRNA発現上昇と抗うつ作用との関連性に関する検討2009
    • Author(s)
      東田道久, 他計6名
    • Organizer
      第26回和漢医薬学会大会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 和漢薬で3万人の命を救おう!～新規うつ病因子の解明と治療薬開発への戦略～2009
    • Author(s)
      東田道久
    • Organizer
      富山漢方会
    • Place of Presentation
      富山
    • Year and Date
      2009-08-26
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 補中益気湯によるセロトニン2C受容体応答調節とその有効成分解析2009
    • Author(s)
      東田道久, 他計4名
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21249047

  • [Presentation] 筋萎縮性側索硬化症モデルマウスを用いた温脾湯の検討.2008
    • Author(s)
      関谷倫子、田原愛、一柳孝司、池城安正、東田千尋、横澤隆子
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] The molecular mechanism of sominone which enhance neuronal network formation2008
    • Author(s)
      Tohda, C., Joyashiki, E
    • Organizer
      The 81st Annual Meeting of The Japanese Pharmacological Society
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] 老化促進モデルマウスの記憶障害に対する柿ポリフェノールオリゴマーの影響2008
    • Author(s)
      李 英蛾、趙 恩珠、田中 隆、東田 千尋、横澤 隆子
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] The effect of Wen-Pi-Tang on disease progression of amyotrophic lateral sclerosis model mice2008
    • Author(s)
      Sekiya, M., Tahara, A. Ichiyanagi, T., Ikeshiro, Y., Tohda, C., Yokozawa, T
    • Organizer
      The 128th Annual Meeting of the Pharmaceutical Society of Japan
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] 神経回路網形成を促進するsominoneの作用機序.2008
    • Author(s)
      東田千尋、城屋敷枝里
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] 筋萎縮性側索硬化症モデルマウスを用いた温脾湯の検討2008
    • Author(s)
      関谷 倫子、田原 愛、一柳 孝司、池城 安正、東田 千尋、横澤 隆子
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] 老化促進モデルマウスの記憶障害に対する柿ポリフェノールオリゴマーの影響.2008
    • Author(s)
      李英蛾、趙 恩珠、田中 隆、東田千尋、横澤隆子、
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Influence of persimmon polyphenolic oligomers on memory impairment in senescence accelerated mouse prone 8(SAMP8)2008
    • Author(s)
      Lee, Y.A, Cho, E.J., Tanaka, T., Tohda, C., Yokozawa, T
    • Organizer
      The 128th Annual Meeting of the Pharmaceutical Society of Japan
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] 神経回路網形成を促進するsominoneの作用機序2008
    • Author(s)
      東田 千尋、城屋敷 枝里
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Neuropharmacological evidence for availability of a Kampo medicine Chotosan in clinical treatment of vascular dementia: From behavior to molecular aspect2007
    • Author(s)
      Matsumoto, K., Zhao, Q., Murakami, Y., Tohda, M., Obi, R., Shimada, Y
    • Organizer
      Joint Symposium: Evidence-based Approach to Traditional Medicine and Modern Medicine
    • Place of Presentation
      Beijing
    • Year and Date
      2007-06-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Presentation] ADHD-loke behaviors and hypoplasia of myelinated axons in PI3 kinase knockout mice2007
    • Author(s)
      Nakanishi, R., Tohda, C., Yokozawa, T., Yamamoto, T., Kadowaki, M
    • Organizer
      The 80st Annual Meeting of The Japanese Pharmacological Society
    • Place of Presentation
      Nagoya
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] PI3KノックアウトマウスのADHD様行動とミエリン化軸索の形成不全.2007
    • Author(s)
      中西類子、東田千尋、横澤隆子、山本武、門脇真
    • Organizer
      第80回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] 帰脾湯による記憶障害改善作用のメカニズム2007
    • Author(s)
      城屋敷 枝里、内藤 理絵、東田 千尋
    • Organizer
      Neuro2007 第50回目本神経化学会大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Kampo formula Kihi-to improves memory disorder in Alzheimer's disease model mice by calpain inhibition2007
    • Author(s)
      Naito, R., Tohda, C., Yokozawa, T
    • Organizer
      The 80th Annual Meeting of The Japanese Pharmacological Society
    • Place of Presentation
      Nagoya
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] The mechanism of memory improvement by Kihi-to2007
    • Author(s)
      Joyashiki, E., Naito, R., Tohda, C
    • Organizer
      Neuro2007 The 49th Annual Meeting of The Japanese Society for Neurochemistry
    • Place of Presentation
      Nagoya
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Therapeutic potency of Kampo medicine against neurodegenerative disease by multiple molecular mechanisms of enhamcing neuronal polarity.(Symposium)2007
    • Author(s)
      Tohda, C
    • Organizer
      The 127th Annual Meeting of the Pharmaceutical Society of Japan
    • Place of Presentation
      Toyama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] セロトニン2C受容体mRNA short variantの経日的発現量変化とRNA editingとの関連性2007
    • Author(s)
      東田道久, 他計4名
    • Organizer
      第58回日本薬理学会北部会
    • Place of Presentation
      札幌
    • Year and Date
      2007-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Presentation] 帰脾湯によるアルツハイマー型記憶障害の改善作用におけるcalpainの関与.2007
    • Author(s)
      内藤理絵、東田千尋、横澤隆子
    • Organizer
      第80回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] ウコン類生薬の基原と品質2007
    • Author(s)
      小松かつ子, 佐々木陽平, 田中謙, 東田千尋
    • Organizer
      第9回応用薬理シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-09-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Presentation] 帰脾湯による記憶障害改善作用のメカニズム.2007
    • Author(s)
      城屋敷枝里、内藤理絵、東田千尋
    • Organizer
      Neuro2007 第50回日本神経化学会大会
    • Place of Presentation
      名古屋
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Neuronの極性形成を促進させるmultiple molecular mechanismにより神経変性疾患を治療する和漢薬.2007
    • Author(s)
      東田千尋
    • Organizer
      日本薬学会第127年会(シンポジウム)
    • Place of Presentation
      富山
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] 補中益気湯長期間処置によるNG108-15細胞の遺伝子発現変化2007
    • Author(s)
      東田道久, 松本欣三
    • Organizer
      第24回和漢医薬学会大会
    • Place of Presentation
      富山
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Presentation] 細胞内cAMP濃度に依存した釣藤散によるM-CSF mRNA発現の両方向性調節2007
    • Author(s)
      東田道久
    • Organizer
      第24回和漢医薬学会大会
    • Place of Presentation
      富山
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Presentation] セロトニン2C 受容体の第三細胞内ループをコードする RNA 上に存在する4箇所の新規 editing 部位2007
    • Author(s)
      東田道久, 他計4名
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Presentation] Botanical source and quality of Crucuma drugs2007
    • Author(s)
      Komatsu, K., Sasaki, Y., Tanaka, K., Tohda, C
    • Organizer
      The 9th Applied Pharmacology Symposium
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-09-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Presentation] 刺五加メタノールエキスによるシナプス再形成作用と記憶障害改善作用2006
    • Author(s)
      東田千尋, 市村真帆子, 末次一博, 小松かつ子
    • Organizer
      日本薬学会第126年会
    • Place of Presentation
      仙台
    • Year and Date
      2006-03-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Presentation] Development of effective formulation for dementia treatment2006
    • Author(s)
      Matsuyama, S., Tohda, C., Komatsu, K
    • Organizer
      The 23rd Annual Meeting of Medical and Pharmaceutical Society for WAKAN-YAKU
    • Place of Presentation
      Gifu
    • Year and Date
      2006-08-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17406004

  • [Presentation] 神経突起の萎縮とシナプス減少の回復により認知症改善作用を示す和漢薬-行動、組織、分子機序.2006
    • Author(s)
      東田千尋
    • Organizer
      フォーラム「創薬」第20回研究会
    • Place of Presentation
      富山
    • Year and Date
      2006-09-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Investigation of roles of γ-Aminobutyric acid in chronic renal failure rats2006
    • Author(s)
      Sasaki, S., Tohda, C., Owada, S., Yokozawa, T
    • Organizer
      The 27th Meeting of Guanidino compounds
    • Place of Presentation
      Osaka
    • Year and Date
      2006-10-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Antioxidation and neuroprotective effects of Barakol HCl and the extracts from fruit hull of mangosteen2006
    • Author(s)
      Sukma, M., Yahuafai, J., Ngawhirunpat, T., Siripong, P., Sotanaphan, U., Opanasopit, P., Tohda, M
    • Organizer
      The 21th FAPA congress
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Presentation] 帰脾湯によるアルツハイマー型記憶障害の改善作用2006
    • Author(s)
      内藤理絵、東田千尋、横澤隆子
    • Organizer
      日本薬学会第126年会
    • Place of Presentation
      仙台
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Synaptic regeneration and memory improvement by the methanol extract of Eleutherococcus senticosus2006
    • Author(s)
      Tohda, C., Ichimura, M., Suetsugu, K., Komatsu, K
    • Organizer
      The 126th Annual Meeting of the Pharmaceutical Society of Japan
    • Place of Presentation
      Sendai
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Investigation of PI3Kknockout mice as an ADHD model2006
    • Author(s)
      Nakanishi, R., Tohda, C., Yokozawa, T., Yamamoto, T., Kadowaki, M
    • Organizer
      The 115th Regularl Meeting of the Pharmaceutical Society of Japan Hokuriku Branch
    • Place of Presentation
      Toyama
    • Year and Date
      2006-11-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Neuroprotective activity and cytotoxicity of Ocimum sancum2006
    • Author(s)
      Sukma, M., Piriyaprasarth, S., Awale, S., Tohda, M., Kadota, S
    • Organizer
      The 21th FAPA congress
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Presentation] PI3KノックアウトマウスのADHD動物モデルとしての検討.2006
    • Author(s)
      中西類子、東田千尋、横澤隆子、山本武、門脇真
    • Organizer
      日本薬学会北陸支部第115回例会
    • Place of Presentation
      富山
    • Year and Date
      2006-11-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Development of a Kampo formula for anti-dementia2006
    • Author(s)
      Matsuyama, S., Tohda, C., Komatsu, K
    • Organizer
      The 23th Annual Meeting of Medical and Pharmaceutical Society for WAKAN-YAKU
    • Place of Presentation
      Gifu
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Neuroprotective Activities of Manganese Complexes of Curcumin and Diacetylcurcumin in A Kainic Acid-induced Neurotoxicity Model of Rats2006
    • Author(s)
      Matsumoto, K., Sumanont, Y., Murakami, Y., Tohda, T., Vajragupta, O., Watanabe, H
    • Organizer
      The 7th JSPS-NRCT Joint Seminar
    • Place of Presentation
      Toyama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Presentation] Choto-san, a Kampo formula, ameliorates spatial learning behaviour deficits and central cholinergic dysfunction caused by chronic cerebral hvnonerfusion in mice2006
    • Author(s)
      Zhao, Q., Murakami, Y., Tohda, M., Obi, R., Shimada, Y., Matsumoto, K
    • Organizer
      The 7th JSPS-NRCT Joint Seminar
    • Place of Presentation
      Toyama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390209

  • [Presentation] アシュバガンダ成分による神経変性疾患の改善作用.2006
    • Author(s)
      東田千尋
    • Organizer
      第28回日本アーユルヴェーダ学会富山研究総会
    • Place of Presentation
      富山
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] ADHD-like behavior, synaptic loss and hypoplasia of myelinated axons by PI3 kinase deficiency2006
    • Author(s)
      Tohda, C., Nakanishi, R., Yokozawa, T., Kadowaki, M
    • Organizer
      The 49th Annual Meeting of The Japanese Society for Neurochemistry
    • Place of Presentation
      Nagoya
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500249

  • [Presentation] Improvement on spinal cord injury by oral administration of withanoside IV2006
    • Author(s)
      <