UMEHARA Hujio 梅原藤雄

… Alternative Names

Researcher Number	20271140
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2010 : Kagoshima University, 医歯(薬)学総合研究科, 講師 2009 : Kagoshima University, 医歯学総合研究科, 講師 2007 – 2009 : Kagoshima University, 大学院・医歯学総合研究科, 講師 2008 : Kagoshima University, 大学院医歯学総合研究科, 講師 2006 : Kagoshima University, Graduate School of Medical and Dental Sciences, Assistant Professor, 大学院医歯学総合研究科, 講師 … More
Review Section/Research Field	Principal Investigator Neurology / Neurology Except Principal Investigator Neurology / Neurology
Keywords	Principal Investigator Desert hedgehog / シュワン細胞 / 末梢神経 / 遺伝性末梢神経障害 / 遺伝子治療 / ノックアウトマウス / minifascicle / 性分化異常症 / Transgenic mouse / Schwann cell … More Except Principal Investigator VEGF / platelet / PMP22 / POEMS syndrome / PLP / HAM / Crow-Fukase syndrome / P_0 / 脊髄小脳変性症 / Naチャンネル / 高齢発症 / Tdp1 / 中枢性ミエリン / HAM-TSP / 抗ガングリオシド抗体 / ガングリオシド抗体 / ギランバレー症候群 / TDP1 / dN / ミエリン / 発症予測 / coagulation / naked VEGF cDNA / Linkage analysis / HTLV-I proviral load / MMP阻害剤 / HTLM-Iプロウイルス量 / HTLV-1 / 治療法 / Po / TSP / エイズ脳症 / Guillain Barre syndrome / HIV-1 / 遺伝性 / マウスモデル / HTLV-Iプロウイルス量 / 神経変性 / 治療薬開発 / Kチャンネル / 連鎖解析 / cytotoxic T lymphocytes / 予後判定 / Motor sensory neuropathy / dS比 / whole-cell clamp / megakaryocyte / 末梢神経障害 / transgenic mouse / Hereditary / isoform / ion channel / Therapy / 運動感覚神経障害 / 優性遺伝 / ニューロパチー / intraneural injection / matrix metalloproteinase / 劣性遺伝 / MMP / 電位依存性ナトリウムチャネル / SCAN1 / P_O / 治療開発 / glioblastoma / Prognosis / 疾患感受性遺伝子 / HTLV-I-associated myelopathy / DNA修復 / SSBR / 第3染色体 / 選択的MMP阻害剤 / conduction block / 発症病態 / 細胞傷害性Tリンパ球 / metalloproteinase inhibitor / Anti-ganglioside antibody / 電位依存性カリウムチャネル / Chromosome 3 / CIDP / Myelin / neuropathy / Transgenic mouse / nude mouse / susceptible genes / 一本鎖DNA修復 / ノックアウトマウス / バッチクランプ法 Less

Desert hedgehog遺伝子変異による神経障害の病態解明と治療法の開発Principal Investigator
- Principal Investigator
  
  梅原藤雄
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Neuropathogenesis of retrovirus infection : diverse in vivo and ex vivo analysis of HAM/TSP and AIDS encephalopathy.
- Principal Investigator
  
  IZUMO Shuji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Investigation for the pathogenesis of neurological disorders due to Desert hedgehog gene mutation and development of new treatmentPrincipal Investigator
- Principal Investigator
  
  UMEHARA Fujio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Pathogenesis of SCAN1, analysis of Tdp1 knockout mice
- Principal Investigator
  
  HIROSHI Takashima
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Study for the pathogenesis of neuropathy with Desert hedgehog gene mutation and development for the treatmentPrincipal Investigator
- Principal Investigator
  
  UMEHARA Fujio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
The study of neurological abnormalities in the patients with Desert hedgehog gene mutationPrincipal Investigator
- Principal Investigator
  
  UMEHARA Fujio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Exploitation of new therapies for HTLV-I-assotiated myelopathy
- Principal Investigator
  
  OSAME Mitsuhiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Research for hereditary neuropathy caused by desert hedgehog gene mutationPrincipal Investigator
- Principal Investigator
  
  UMEHARA Fujio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
The effect of anti-ganglioside antibodies on ion channels
- Principal Investigator
  
  HIGUCHI Itsuro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Research for the pathogenesis and treatment of Crow-Fukase syndrome
- Principal Investigator
  
  ARIMURA Kimiyoshi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
HAMにおける細胞接着因子の研究Principal Investigator
- Principal Investigator
  
  梅原藤雄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Molecular biology of neurological diseases with abnormality of central or peripheral nerve myelin
- Principal Investigator
  
  NAKAGAWA Masanori
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University

All 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

[Book] G Desert hedgehog遺伝子変異による新しい遺伝性末梢神経障害ブレイン・サイエンスレビュー2004
- Author(s)
  梅原藤雄
- Total Pages
  14
- Publisher
  クバプロ(伊藤正男編)
- Data Source
  KAKENHI-PROJECT-15590900
[Book] Desert hedgehog遺伝子変異による新しい遺伝性末梢神経障害ブレイン・サイエンスレビュー(伊藤正男編)2004
- Author(s)
  梅原藤雄
- Total Pages
  14
- Publisher
  クバプロ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Book] New hereditary neuropathy due to Desert hedgehog gene mutation. (Edited by M.Ito)2004
- Author(s)
  Fujio Umehara
- Publisher
  Kuba Pro
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Book] Gann Monograph on Cancer Research No.502003
- Author(s)
  Fujio Umehara, Mitsuhiro Osame
- Total Pages
  7
- Publisher
  Japan Scientific Societies Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Induction of paranodal myelin detachment and sodium channel loss in vivo by Campylobacter jejuni DNA-binding protein from starved cells (C-Dps) in myelinated nerve fibers2010
- Author(s)
  Hua Piaoa, Motozumi Minohara, 1, Nobutoshi Kawamura, Wei Li, Yoshimitsu Mizunoe, Fujio Umehara, Yoshinobu Goto, Susumu Kusunoki, Takuya Matsushita, Kazuhiro Ikenaka, Takashi Maejima, Jun-ichi Nabekura, Ryo Yamasaki, Jun-ichi Kira
- Journal Title
  
  J Neurological Sciences 288
  
  Pages : 54-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591093
[Journal Article] Expression of the heparin-binding growth factor midkine in the cerebrospinal fluid of patients with neurological disorderS.2008
- Author(s)
  Yoshida Y, Ikematsu S, Muramatsu H, Sakakima H, Mizuma N, Matsuda F, Sonoda K, Umehara F, Ohkubo R, Matsuura E, Goto M, Osame M, Muramatsu T.
- Journal Title
  
  Intern Med 47
  
  Pages : 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] 自己免疫性末梢神経障害血液浄化療法-20082008
- Author(s)
  梅原藤雄
- Journal Title
  
  腎と透析第65巻増刊号
  
  Pages : 454-458
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Inclusion body myositis associated with human T-lymphotropic virus-type I infection: eleven patients from an endemic area in Japan.2008
- Author(s)
  Matsuura E, Umehara F*, Nose H, Higuchi I, Matsuoka E, Izumi K, Kubota R, Saito M, Izumo S, Arimura K, Osame M.
- Journal Title
  
  J Neuropathol Exp Neurol 67
  
  Pages : 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Enlarged, multifocal upper limb neuropathy with HTLV-I associated myelopathy in a patient with chronic adult T-cell leukemia.2008
- Author(s)
  Umehara, F^*. Hagiwara, T. Yoshimura, M. Higashi, K. Arimura, K.
- Journal Title
  
  J Neurol Sci 266
  
  Pages : 167-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Inclusion body myositis associated with human T-lymphotropic virus-type I infection: eleven patients from an endemic area in Japan.2008
- Author(s)
  Matsuura E, Umehara F, Nose H, Higuchi I, Matsuoka E, Izumi K, Kubota R, Saito M, Izumo S, Arimura K, Osame M
- Journal Title
  
  J Neuropathol Exp Neurol 67
  
  Pages : 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390243
[Journal Article] Expression of the heparin-binding growth factor midkine in the cerebrospinal fluid of patients with neurological disorders.2008
- Author(s)
  Yoshida Y, Ikematsu S, Muramatsu H, Umehara F, et al
- Journal Title
  
  Intern Med 47
  
  Pages : 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Inclusion body myositis associated with human T-lymphotropic virus-type I infection: eleven patients from an endemic area in Japan2008
- Author(s)
  Matsuura E, Umehara F*, Nose H, Higuchi I, Matsuoka E, Izumi K, Kubota R, Saito M, Izumo S, Arimura K, Osame M.
- Journal Title
  
  J Neuropathol Exp Neurol 67
  
  Pages : 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Inclusion body myositis associated with human T-lymphotropic virus-type I infection : eleven patients from an endemic area in Japan.2008
- Author(s)
  Matsuura E, Umehara F^*, Nose H, Higuchi I, Matsuoka E, Izumi K, Kubota R, Saito M, Izumo S, Arimura K, Osame M.
- Journal Title
  
  J Neuropathol Exp Neurol 67
  
  Pages : 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Accumulation of human T-lymphotropic virus type I (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy2008
- Author(s)
  Hayashi D, Kubota R, Takenouchi N, Nakamura T, Umehara F, Arimura K, Izumo S, Osame M.
- Journal Title
  
  J Neurovirol 14
  
  Pages : 459-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Accumulation of human T-lymphotropic virus type l (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy.2008
- Author(s)
  Hayashi D, Kubota R, Umehara F, et al.
- Journal Title
  
  J Neurovirol. 14
  
  Pages : 459-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Enlarged, multifocal upper limb neuropathy with HTLV-I associated myelopathy in a patient with chronic adult T-cell leukemia.2008
- Author(s)
  Umehara F, Hagiwara T, Yoshimura M, Higashi K, Arimura K
- Journal Title
  
  J Neurol Sci 266
  
  Pages : 167-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Enlarged multifocal upper limb neuropathy with HTLV-I associated myelopathy in a patient with chronic adult T-cell leukemia2008
- Author(s)
  Umehara, F. Hagiwara, T. Yoshimura, M. Higashi, K. Arimura, K.
- Journal Title
  
  J Neurol Sci 266
  
  Pages : 167-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Expression of the heparin-binding growth factor midkine in the cerebrospinal fluid of patients with neurological disorders2008
- Author(s)
  Yoshida Y, Ikematsu S, Muramatsu H, Sakakima H, Mizuma N, Matsuda F, Sonoda K, Umehara F, Ohkubo R, Matsuura E, Goto M, Osame M, Muramatsu T.
- Journal Title
  
  Intern Med 47
  
  Pages : 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] POEMS 症候群(Crow-Fukase 症候群)2008
- Author(s)
  梅原藤雄、有村公良
- Journal Title
  
  Clinical Neuroscience 26
  
  Pages : 244-245
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Abnormalities of spinal magnetic resonance images implicate clinical variability in human T-cell lymphotropic virus type I-associated myelopathy.2007
- Author(s)
  Umehara F, Nose H, Saito M, Fukuda M, Ogino M, Toyota T, Yuhi T, Arimura K, Osame M.
- Journal Title
  
  J Neurovirol 13
  
  Pages : 260-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Spinocerebellar ataxia with axonal neuropathy : consequence of a Tdp1 recessive neomorphic mutation2007
- Author(s)
  Hirano R, Interthal H, Huang C, Nakamura T, Deguchi K, Choi K, Bhattacharjee MB, Arimura K, Umehara F, Izumo S, Northrop JL, Salih MA, Inoue K, Armstrong DL, Champoux JJ, Takashima H, Boerkoel CF
- Journal Title
  
  EMBO J. 26
  
  Pages : 4732-4743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Abnormalities of spinal magnetic resonance images implicate clinical variability in human T-cell lymphotropic virus type I-associated myelopathy2007
- Author(s)
  Umehara F, Nose H, Saito M, Fukuda M, Ogino M, Toyota T, Yuhi T, Arimura K, Osame M.
- Journal Title
  
  J Neurovirol 13
  
  Pages : 260-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] 末梢神経障害の治療の進歩2007
- Author(s)
  梅原藤雄、有村公良
- Journal Title
  
  神経治療学 24
  
  Pages : 445-448
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Spinocerebellar ataxia with axonal neuropathy : consequence of a Tdp1 recessive neomorphic mutation?2007
- Author(s)
  Hirano R, Interthal H, Huang C, Nakamura T, Deguchi K, Choi K, Bhattacharjee MB, Arimura K, Umehara F, Izumo S, Northrop JL, Salih MA, Inoue K, Armstrong DL, Champoux JJ, Takashima H, Boerkoel CF
- Journal Title
  
  EMBO J. 26(22)
  
  Pages : 4732-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591001
[Journal Article] Early clinical signs and imaging findings in Gerstmann-Straussler-Scheinker syndrome (Pro102Leu).2006
- Author(s)
  Hitoshi Arata, Hiroshi Takashima, Fujio Umehara, et al.
- Journal Title
  
  Neurology 66(11)
  
  Pages : 1672-1678
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] MRI studies of spinal visceral larva migrans syndrome.2006
- Author(s)
  Fujio Umehara, Hideki Ookatsu, Daisuke Hayashi, et al.
- Journal Title
  
  J Neurol Sci 249(1)
  
  Pages : 7-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] The structural and functional integrity of peripheral nerves depends on the glial-derived signal Desert Hedgehog.2006
- Author(s)
  S.Sharghi-Namini, M.Turmaine, C.Meier, V.Sahni, Fujio Umehara, et al.
- Journal Title
  
  J Neurosci 26(23)
  
  Pages : 6364-6376
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Elevated anxiety-like and depressive behavior in Desert hedgehog knockout male mice2006
- Author(s)
  Fujio Umehara, Kenichi Mishima, Nobuaki Egashira, et al.
- Journal Title
  
  Behavioural Brain Research 174(1)
  
  Pages : 167-173
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Early clinical signs and imaging findings in Gerstmann-Straussler-Scheinker syndrome (Pro102Leu).2006
- Author(s)
  Hitoshi Arata, Hiroshi Takashima, Ryuki Hirano, Hisanori Tomimitsu, Koichi Machigashira, Kotaro Izumi, Mitsuro Kikuno, A.R. Ng, Fujio Umehara, Takayo Arisato, Ryuichi Ohkubo, Y. Nakabeppu, M. Nakajo, Mitsuhiro Osame, Kimiyoshi Arimura.
- Journal Title
  
  Neurology 66
  
  Pages : 1672-1678
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] MRI studies of spinal visceral larva migrans syndrome.2006
- Author(s)
  Fujio Umehara, Hideki Ookatsu, Daisuke Hayashi, Akifumi Uchida, Yukari Douchi, H. et al.
- Journal Title
  
  J Neurol Sci 249(1)
  
  Pages : 7-12
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Early clinical signs and imaging findings in Gerstmann-Straussler-Scheinker syndrome (Pro102Leu).2006
- Author(s)
  Hitoshi Arata, Hiroshi Takashima, Ryuki Hirano, Fujio Umehara, et al.
- Journal Title
  
  Neurology 66(11)
  
  Pages : 1672-1678
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] The structural and functional integrity of peripheral nerves depends on the glial-derived signal Desert Hedgehog.2006
- Author(s)
  S.Sharghi-Namini, M.Turmaine, C.Mejer, V.Sahni, Fujio Umehara, K.R.Jessen, R.Mirsky.
- Journal Title
  
  J Neurosci 26(23)
  
  Pages : 6364-6376
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] MRI studies of spinal visceral larva migrans syndrome.2006
- Author(s)
  Fujio Umehara, Hideki Ookatsu, Daisuke Hayashi, Akifumi Uchida, Yukari Douchi, H.Kawabata, Rina Goto, Akihiro Hashiguchi, Eiji Matsuura, Ryuichi Okubo, Itsuro Higuchi, Kimiyoshi Arimura, Y.Nawa, Mitsuhiro Osame.
- Journal Title
  
  J Neurol Sci 249
  
  Pages : 7-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Desert hedgehog-Patched 2 expression in peripheral nerves during Wallerian degeneration and regeneration.2006
- Author(s)
  Sepideh N Bajestan, Fuiio Umehara, Yuko Shirahama, et al.
- Journal Title
  
  J Neurobiology 66・3
  
  Pages : 243-255
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Relapsing cervical cord lesions on MRI in patients with HTLV-I-associated myelopathy.2006
- Author(s)
  Fuiio Umehara, N Tokunaga, Y Hokezu, E Hokonohara, et al.
- Journal Title
  
  Neurology 66・2
  
  Pages : 289-289
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] The structural and functional integrity of peripheral nerves depends on the glial-derived signal Desert Hedgehog2006
- Author(s)
  S.Sharghi-Namini, M.Turmaine, C.Meier, V.Sahni, Fujio Umehara, K.R.Jessen, R.Mirsky.
- Journal Title
  
  J Neurosci 26
  
  Pages : 6364-6376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Elevated anxiety-like and depressive behavior in Desert hedgehog knockout male mice.2006
- Author(s)
  Fujio Umehara, Kenichi Mishima, Nobuaki Egashira, Ayumi Ogata, Katsunori Iwasaki, Michihiro Fujiwara.
- Journal Title
  
  Behavioral Brain Research 174
  
  Pages : 167-173
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Desert hedgehog-Patched 2 expression in peripheral nerves during Wallerian degeneration and regeneration.2006
- Author(s)
  Sepideh N Bajestan, Fujio Umehara, Yuko Shirahama, et al.
- Journal Title
  
  J Neurobiology 66(3)
  
  Pages : 243-255
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Motor-sensory neuropathy with minifascicle formation in a woman with normal karyotype2006
- Author(s)
  A.landrini, S.Gambelli, M.Muglia, G.Berti, A.Patitucci, K.Sugie, F.Umehara, et al.
- Journal Title
  
  Neurology 65
  
  Pages : 776-776
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Unilateral toe-walking secondary to intramuscular hemangioma in the gastrocnemius.2006
- Author(s)
  Fujio Umehara, E.Matsuura, S.Kitajima, M.Osame.
- Journal Title
  
  Neurology 65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] New mutation of gap junction protein beta1(GJB1) gene in X-linked hereditary motor and sensory neuropathy.2006
- Author(s)
  Fujio Umehara, Yumiko Arimura, Mitsuhiro Osame, S. Minato, Keiichi Nakahara.
- Journal Title
  
  J Peripher Nerv Syst 11(1)
  
  Pages : 96-97
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] New mutation of gap junction protein beta1 (GJB1) gene in X-linked hereditary motor and sensory neuropathy.2006
- Author(s)
  Fujio Umehara, Yumiko Arimura, Mitsuhiro Osame, S. Minato, Keiichi Nakahara.
- Journal Title
  
  J Peripher Nerv Syst 11
  
  Pages : 96-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Relapsing cervical cord lesions on MRI in patients with HTLV-I-associated myelopathy.2006
- Author(s)
  Fujio Umehara, Hiroyasu Tokunaga, Yoichi Hokezu, et al.
- Journal Title
  
  Neurology 66(2)
  
  Pages : 289-289
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] New mutation of gap junction protein beta1 (GJB1) gene in X-linked hereditary motor and sensory neuropathy.2006
- Author(s)
  Fujio Umehara, Yumiko Arimura, Mitsuhiro Osame, et al.
- Journal Title
  
  J Peripher Nerv Syst 11(1)
  
  Pages : 96-97
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Desert hedgehog-Patched 2 expression in peripheral nerves during Wallerian degeneration and regeneration.2006
- Author(s)
  Sepideh N Bajestan, Fujio Umehara, Yuko Shirahama, et al.
- Journal Title
  
  J Neurobiology 66
  
  Pages : 243-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Relapsing cervical cord lesions on MRI in patients with HTLV-I-associated myelopathy.2006
- Author(s)
  Fujio Umehara, Hiroyasu Tokunaga, Yoichi Hokezu, Ei Hokonohara, Koichi Yoshishige, Tadafumi Shiraishi, Ryuichi Okubo, Mitsuhiro Osame.
- Journal Title
  
  Neurology 66
  
  Pages : 289-289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Age associated axonal features in HNPP with 17p11.2 deletion in Japan2006
- Author(s)
  H.Koike, M.Hirayama, M.Yamamoto, H.Ito, N.Hattori, Fujio Umehara, et al.
- Journal Title
  
  J Neurol Neurosurg Psychiat 76
  
  Pages : 1109-1114
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Unilateral toe-walking secondary to intramuscular hemangioma in the gastrocnemius2005
- Author(s)
  Fujio Umehara, E.Matsuura, S.Kitajima, M.Osame.
- Journal Title
  
  Neurology 65・7
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Motor-sensory neuropathy with minifascicle formation in a woman with normal karyotype.2005
- Author(s)
  A.Malandrini, S.Gambelli, M.Muglia, G.Berti, A.Patitucci, K.Sugie, F.Umehara, et al.
- Journal Title
  
  Neurology 65(5)
  
  Pages : 776-776
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Motor-sensory neuropathy with minifascicle formation in a woman with normal karyotype2005
- Author(s)
  A.Malandrini, S.Gambelli, M.Muglia, G.Berti, A.Patitucci, K.Sugie, F.Umehara, et al.
- Journal Title
  
  Neurology 65・5
  
  Pages : 776-776
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Age associated axonal features in HNPP with 17p11.2 deletion in Japan2005
- Author(s)
  H.Koike, M.Hirayama, M.Yamamoto, H.Ito, N.Hattori, Fuiio Umehara, et al.
- Journal Title
  
  J Neurol Neurosurg Psychiat 76・8
  
  Pages : 1109-1114
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Age associated axonal features in HNPP with 17p 11.2 deletion in Japan.2005
- Author(s)
  H.Koike, M.Hirayama, M.Yamamoto, H.Ito, N.Hattori, Fujio Umehara, et al.
- Journal Title
  
  J Neurol Neurosurg Psychiat 76(8)
  
  Pages : 1109-1114
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Unilateral toe-walking secondary to intramuscular hemangioma in the gastrocnemius.2005
- Author(s)
  Fujio Umehara, E.Matsuura, S.Kitajima, M.Osame
- Journal Title
  
  Neurology 65(7)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] MRIで頚髄に異常信号を示し、血清・髄液中抗HTLV-I抗体陽性のミエロパチー3症例:variant form of HAM?2004
- Author(s)
  梅原藤雄, 長友修一郎, 吉重幸一, 新村昌弘, 斉藤峰輝, 古川良尚, 他
- Journal Title
  
  神経免疫学 12・1
  
  Pages : 40-40
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] 胃切除術後に発症し、血中Vascular endothelial growth factor (VEGF)が高値を呈したビタミンB1欠乏性ニューロパチーの1症例2004
- Author(s)
  中川広人, 米田誠, 前田亜佐子, 梅原藤雄, 栗山勝
- Journal Title
  
  臨床神経学 44
  
  Pages : 91-95
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Neurologic manifestations of Kanzaki disease.2004
- Author(s)
  Fujio Umehara, Matsumuro K, Kurono Y, Arimura K, et al.
- Journal Title
  
  Neurology 62
  
  Pages : 1604-1606
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] SET binding factor 2(SBF2) mutation causes CMT4B with juvenile onset glaucoma.2004
- Author(s)
  Hirano R, Takashima H, Fujio Umehara, Arimura H, et al.
- Journal Title
  
  Neurology 63
  
  Pages : 577-580
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Beneficial effects of mild lifelong dietary restriction on skeletal muscle : prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin2004
- Author(s)
  Fusako Usuki, Akira Yasutake, Fujio Umehara, Itsuro Higuchi
- Journal Title
  
  Acta Neuropathol 108・1
  
  Pages : 1-9
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] MRIで頚髄に異常信号を示し、血清・髄液中抗HTLV-1抗体陽性のミエロパチー3症例:variant form of HAM?2004
- Author(s)
  梅原藤雄, 長友修一郎, 吉重幸一, 新村昌弘, 斉藤峰輝, 古川良尚, 他
- Journal Title
  
  神経免疫学 12
  
  Pages : 40-40
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Neurologic manifestations of Kanzaki disease2004
- Author(s)
  Fujio Umehara, Matsumuro K, Kurono Y, Arimura K, et al.
- Journal Title
  
  Neurology 62
  
  Pages : 1604-1606
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Chronic progressive cervical myelopathy with HTLV-I infection : variant form of HAM/TSP?2004
- Author(s)
  Fujio Umehara, S.Nagatomo, K.Yoshishige, et al.
- Journal Title
  
  Neurology 63
  
  Pages : 1276-1280
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Chronic progressive cervical myelopathy with HTLV-I infection : variant form of HAM/TSP?2004
- Author(s)
  Fujio Umehara, S.Nagatomo, K.Yoshishige, et al.
- Journal Title
  
  Neurology 63・7
  
  Pages : 1276-1280
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Chronic progressive cervical myelopathy with HTLV-I infection : Variant form of HAM/TSP?2004
- Author(s)
  Umehara F, et al.
- Journal Title
  
  Neurology. 63(7)
  
  Pages : 1276-1280
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207031
[Journal Article] Chronic progressive cervical myelopathy with HTLV-I infection : variant form of HAM/TSP?2004
- Author(s)
  Fujio Umehara, S.Nagatomo, K.Yoshishige, et al.
- Journal Title
  
  Neurology 63(7)
  
  Pages : 1276-1280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] 胃切除術後に発症し、血中Vascular endothelial growth factor (VEGF)が高値を呈したビタミンB1欠乏性ニューロパチーの1症例2004
- Author(s)
  中川広人, 米田誠, 前田亜佐子, 梅原藤雄, 栗山勝
- Journal Title
  
  臨床神経学 44・2
  
  Pages : 91-95
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Beneficial effects of mild lifelong dietary restriction on skeletal muscle : prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin2004
- Author(s)
  Fusako Usuki, Akira Yasutake, Fujio Umehara, Itsuro Higuchi
- Journal Title
  
  Acta Neuropathol 108
  
  Pages : 1-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Three cases of carvical myelopathy with HTLV-I infection : Variant form of HAM?2004
- Author(s)
  Fujio Umehara, S.Nagatomo, K.Yoshishige, M.Shinmura, M.Saito, Y.Furukawa, et al.
- Journal Title
  
  Neuroimmunology 12
  
  Pages : 40-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] HTLV-I関連症候群2004
- Author(s)
  梅原藤雄
- Journal Title
  
  臨床看護 30・6
  
  Pages : 989-992
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Neurologic manifestations of Kanzaki disease2004
- Author(s)
  Fujio Umehara, Matsumuro K, Kurono Y, Arimura K, et al.
- Journal Title
  
  Neurology 62・9
  
  Pages : 1604-1606
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] SET binding factor 2 (SBF2) mutation causes CMT4B with juvenile onset glaucoma2004
- Author(s)
  Hirano R, Takashima H, Fujio Umehara, Arimura H, et al.
- Journal Title
  
  Neurology 63・3
  
  Pages : 577-580
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Beneficial effects of mild lifelong dietary restriction on skeletal muscle : prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin.2004
- Author(s)
  Fusako Usuki, Akira Yasutake, Fujio Umehara, Itsuro Higuchi
- Journal Title
  
  Acta Neuropathol 108(1)
  
  Pages : 1-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] HTLV-I-associated disorders.2004
- Author(s)
  Fujio Umehara
- Journal Title
  
  Rinsho Kango 30
  
  Pages : 989-992
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] SET binding factor 2 (SBF2) mutation causes CMT4B with juvenile onset glaucoma2004
- Author(s)
  Hirano R, Takashima H, Fujio Umehara, Arimura H, et al.
- Journal Title
  
  Neurology 63
  
  Pages : 577-580
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Thiamine deficiency polyneuropathy after gastrectomy associated with high level of serum vascular enothelial growth factor(VEGF).2004
- Author(s)
  H.Nakagawa, M.Yoneda, A.Maeda, Fujio Umehara, M.Kuriyama
- Journal Title
  
  Rinsho Shinkeigaku 44
  
  Pages : 91-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] HTLV-I関連症候群2004
- Author(s)
  梅原藤雄
- Journal Title
  
  臨床看護 30
  
  Pages : 989-992
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] HAMの病態と治療2003
- Author(s)
  納光弘, 宇宿功市郎, 梅原藤雄, 斉藤峰輝, 古川良尚, 久保田龍二, 他
- Journal Title
  
  日本内科学会雑誌 92
  
  Pages : 65-74
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Posterior interosseous nerve syndrome with hourglass-like fascicular constriction of the nerve.2003
- Author(s)
  Fujio Umehara, Yoshino S, Arimura Y, Fukuoka T, Arimura K, et al.
- Journal Title
  
  J Neurol Sci 215(1-2)
  
  Pages : 111-113
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] 「研究成果報告書概要(欧文)」より2003
- Author(s)
  Fujio Umehara, Mitsuhiro Osame
- Journal Title
  
  Gann Monograph on Cancer Research(Japan scientific societies Press) No.55
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Posterior interosseous nerve syndrome with hourglass-like fascicular constriction of the nerve.2003
- Author(s)
  Fujio Umehara, Yoshino S, Arimura Y, Fukuoka T, Arimura K, et al.
- Journal Title
  
  J Neurol Sci 215・1-2
  
  Pages : 111-113
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Crow-Fukase症候群とVEGF2003
- Author(s)
  有村公良, 橋口照人, 梅原藤雄
- Journal Title
  
  神経研究の進歩 47・4
  
  Pages : 545-554
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Crow-Fukase症候群とVEGF2003
- Author(s)
  有村公良, 橋口照人, 梅原藤雄
- Journal Title
  
  神経研究の進歩 47
  
  Pages : 545-554
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Crow-Fukase syndrome and VEGF.2003
- Author(s)
  K.Arimura, T.Tashiguchi, Fujio Umehara
- Journal Title
  
  Shinkei Shinpo 47
  
  Pages : 545-554
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] HAMの病態と治療2003
- Author(s)
  納光弘, 宇宿功市郎, 梅原藤雄, 斉藤峰輝, 古川良尚, 久保田龍二, 他
- Journal Title
  
  日本内科学会雑誌 92・9
  
  Pages : 65-74
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Posterior interosseous nerve syndrome with hourglass-like fascicular constriction of the nerve.2003
- Author(s)
  Fujio Umehara, Yoshino S, Arimura Y, Fukuoka T, Arimura K, et al.
- Journal Title
  
  J Neurol Sci 215
  
  Pages : 111-113
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] 「研究成果報告書概要(欧文)」より2003
- Author(s)
  M.Osame, K.Usuku, Fujio Umehara, M.Saito, Y.Furukawa, R.Kubota, et al.
- Journal Title
  
  Nippon Naika Gakkai Zasshi 92
  
  Pages : 65-74
- Data Source
  KAKENHI-PROJECT-15590900
[Presentation] Recent development in the study of HTLV-I associated neurological disorders : HTLV-I associated inclusion body myositis2009
- Author(s)
  Fujio Umehara
- Organizer
  Second German Japanese Neuroimmunology Symposium
- Place of Presentation
  Garmisch Partenkirchen/Germany
- Year and Date
  2009-07-12
- Data Source
  KAKENHI-PROJECT-21591093
[Presentation] HAM脊髄活動性炎症部にはIL-17が発現している2009
- Author(s)
  梅原藤雄, 白濱ゆう子, 橋口照人
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台国際センター(仙台市)
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-19390243
[Presentation] Desert hedgehog遺伝子移入による末梢神経障害治療法の開発2008
- Author(s)
  梅原藤雄
- Organizer
  厚生労働省難治性ニューロパチーの病態に基づく新規治療法の開発班会議
- Place of Presentation
  東京
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19591000
[Presentation] Desert hedgehog遺伝子移入による末梢神経障害治療法の開発2007
- Author(s)
  梅原藤雄、白濱ゆう子、有村公良川原幸一、橋口照人、丸山征郎楯玄秀
- Organizer
  平成19年度厚生労働省難治性ニューロパチーの病態に基づく新規治療法の開発研究班会議
- Place of Presentation
  東京
- Year and Date
  2007-12-06
- Data Source
  KAKENHI-PROJECT-19591000

1. ARIMURA Kimiyoshi (20159510)

# of Collaborated Projects : 8results

# of Collaborated Products : 46results
2. OSAME Mitsuhiro (10041435)

# of Collaborated Projects : 6results

# of Collaborated Products : 14results
3. IZUMO Shuji (30143811)

# of Collaborated Projects : 3results

# of Collaborated Products : 1results
4. HASHIGUCHI Teruto (70250917)

# of Collaborated Projects : 3results

# of Collaborated Products : 1results
5. HIROSHI Takashima (80372803)

# of Collaborated Projects : 2results

# of Collaborated Products : 4results
6. KUBOTA Ryuji (70336337)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
7. ARIMURA Kimiyoshi (30140908)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. NAKAGAWA Masanori (50198040)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
9. TATE Genshu (10216997)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
10. HURUKAWA Yoshitaka (00359978)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. OKAMOTO Mika (90336347)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. MORI Kazuyasu (20270655)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. HIGUCHI Itsuro (80183573)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. KAMEYAMA Masaki (60150059)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. KASUNOKI Susumu (90195438)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. MARUYAMA Ikurou (20082282)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. USUKU Koichiro (30281223)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. 北島勲 (50214797)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. HIRANO Ryuki

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
20. NAKAMURA Tomonori

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
21. OKAMOTO Yuji

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. HASHIGUCHI Akihiro

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
23. BOERKOEL Cornelius F.

# of Collaborated Projects : 1results

# of Collaborated Products : 1results

UMEHARA Hujio 梅原 藤雄

UMEHARA Fujio 梅原 藤雄

Research Projects

Research Products

Co-Researchers

Desert hedgehog遺伝子変異による神経障害の病態解明と治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Neuropathogenesis of retrovirus infection : diverse in vivo and ex vivo analysis of HAM/TSP and AIDS encephalopathy.

Principal Investigator

Project Period (FY)

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Research Institution

Investigation for the pathogenesis of neurological disorders due to Desert hedgehog gene mutation and development of new treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Pathogenesis of SCAN1, analysis of Tdp1 knockout mice

Principal Investigator

Project Period (FY)

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Research Institution

Study for the pathogenesis of neuropathy with Desert hedgehog gene mutation and development for the treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of neurological abnormalities in the patients with Desert hedgehog gene mutationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploitation of new therapies for HTLV-I-assotiated myelopathy

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Research for hereditary neuropathy caused by desert hedgehog gene mutationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of anti-ganglioside antibodies on ion channels

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for the pathogenesis and treatment of Crow-Fukase syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HAMにおける細胞接着因子の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biology of neurological diseases with abnormality of central or peripheral nerve myelin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] G Desert hedgehog遺伝子変異による新しい遺伝性末梢神経障害ブレイン・サイエンスレビュー2004

Author(s)

Total Pages

UMEHARA Hujio 梅原藤雄

UMEHARA Fujio 梅原藤雄

[Book] Desert hedgehog遺伝子変異による新しい遺伝性末梢神経障害ブレイン・サイエンスレビュー(伊藤正男編)2004