Kameyama Masaki 亀山正樹

… Alternative Names

Researcher Number	60150059
Other IDs
External Links
Affiliation (Current)	2019 : 鹿児島大学, 医歯学総合研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2019 : 鹿児島大学, 医歯学総合研究科, 客員研究員 2017 : 鹿児島大学, 医歯学総合研究科, 客員研究員 2015 – 2016 : 鹿児島大学, 医歯学域医学系, 教授 2011 : 鹿児島大学, 大学院・医歯学総合研究科, 教授 2010 – 2011 : 鹿児島大学, 医歯学総合研究科, 教授 … More
Review Section/Research Field	Principal Investigator General physiology / General physiology / 神経・脳内生理学 Except Principal Investigator Neurology / Pathological medical chemistry / Biomedical engineering/Biological material science / Neurology / General physiology / Otorhinolaryngology / 医学一般 / Basic Section 48020:Physiology-related
Keywords	Principal Investigator Caチャネル / 心筋細胞 / パッチクランプ / patch clamp / Ca channel / カルパスタチン / run-down / calpastatin / リン酸化 / カルモジュリン … More Except Principal Investigator パッチクランプ / カルシウムチャンネル / 心筋 / ATP / Isaacs症候群 / Naチャンネル / カルパスタチン / カルシウム / 筋小胞体 / ミオキミア / AP-1 / 筋けいれん / イオンチャンネル / muscle cramp / K+ channel / Kチャンネル / カリウムチャンネル / Kチャネル / 血管平滑筋 / myokymia / 電位依存性カリウムチャネル / パッチクランプ法 / 自己抗体 / 味覚 / Oregon-green-BAPTA-1 / 共焦点レーザ顕微鏡 / Isaacs' syndrome / ギャップ結合 / conduction block / 機械受容チャンネル / リアノジン / 遺伝子発現 / 抗原認識部位 / CaによるCa放出機構 / 長鎖不飽和脂肪酸 / ネズミ副腎髄質 / anti VGKC antibody / Nav1.4 / 鼓索神経 / 甲状腺機能亢進症 / オレゴン・グリーンBAPTA / voltage-gated potassium channel / 抗ガングリオシド抗体 / Atrial natriuretic factor / 膜輸送活性 / jvs(juvenile visceral steatosis)マウス / 甲状腺中毒性周期性四肢麻 / ギランバレー症候群 / Ca電流 / 遺伝子多型 / Rhodamine green dextran / 尿素サイクル / Mouse adrenal medulla / Calpain / アセチルコリン受容体抗体 / 腕モデル / Amino acid / 高アンモニア血症 / 肝細胞 / Urea cycle / 筋形質膜 / Rat / Western blot / muscle ion channel / グルマリン / ロダミン-グリーン-デキストラン / differential display / 塩素チャンネル / 味覚修飾作用 / イノシトール,三燐酸 / スプライシング / 心肥大 / Calpastatin / 甘味物質 / 細胞内Ca量 / Guillain Barre syndrome / bull frog's sciatic nerve / distributions of induced eddy current / Carnitine / arm tank model / c-jun / 免疫沈降法 / Caチャンネル / AM / Clチャンネル / グルココルチコイド / 副腎髄質細胞 / 伸展受容チャンネル / ラット / Na+ channel / Synergistic effect / gap-junction / グルタミン酸ソーダ / Cardiac hypertrophy / autoantibody / cranium model / 重症筋無力症 / うま味 / 官能検査 / ナトリウムチャネル / 自己免疫疾患 / ルシファーイエロウ / 末梢神経障害 / peripheral nerve hyperexcitability / 骨格筋 / Hyperammonemia / CaによるCa放出 / CIDP / 末梢神経興奮性異常 / Citric acids / イノシト-ルによるCa放出機構 / 免疫組織染色 / Isaacs'syndrome / クエン酸 / ion channel / PCR / 自己抗体、 / 甘味 / 頭蓋内脳槽モデル / ヒト / マウス副腎髄質 / thyrotoxic periodic paralysis / プラズモン共鳴法 / 伸展感受性チャンネル / 電位依存性kチャネル / Ca動員機構 / 二瓶選択法 / リン酸化 / Calcium / クロ-ニング / 相乗効果 / 可溶性澱粉 / 磁気刺激 / Calcium channel / 渦電流分布 / 抗VGKC抗体 / ベジクル脂質平面膜 / the cytosolic CaィイD12+ィエD1concentration / 電位依存性Kチャネル / Taste / Differential display / 筋痙攣 / カルモジュリン / カエルの坐骨神経 / 電位依存性ナトリウムチャネル / magnetic stimulation / prolonged exercise test / クローニング / 家族性周期性四肢麻痺 / Calmodulin / Long-chain unsaturated fatty acid / 共焦点レーザー顕微鏡 / confocal microscope / カルパイン / immunoprecipitation / 遺伝子変異 / 抗チャネル抗体 / western blot / whole-cell clamp / patch clamp method / 甲状腺中毒性周期性四肢麻痺 / オレゴングリーンBAPTA-1 / カルニチン / lucifer yellow / ガングリオシド抗体 / 大錐体神経 / JVS(Juvenile Visceral Steatosis)マウス / 周期性四肢麻痺 / Anti-ganglioside antibody / Human / 哺乳類 / Calcium-channel / パッチ固定法 / Umami / 抗イオンチャネル抗体 / immunonohistochemistry / polymorphism / JUS(juvenile Visceral Steatosi s)マウス / JVS (Juvenile Visceral Steatosis) mouse / カリウムチャネル / アミノ酸 / バッチクランプ法 Less

Molecular mechanism of self-regulation of Cav1.2 channel by channel cytoplasmic fragmentsOngoing
- Principal Investigator
  
  徐建軍
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kagoshima University
Study on the regulatory mechanisms of L-type Ca2+ channelsPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
An interrelation among regulatory mechanisms of cardiac Ca2+channelsPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Molecular mechanisms underlying Ca2^<+>-dependent facilitation and inactivation of L-type Ca^<2+> channelsPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Molecular mechanisms of regulation of L-type Ca channelsPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Genetic determination and pathogenesis in thyrotoxic periodic paralysis
- Principal Investigator
  
  ARIMURA Kimiyoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Complexity of the regulation of L-type calcium channelsPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Mechanisms for regulation of L-type Ca channels by intracellular factorsPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
表面プラズモン共鳴を用いた抗イオンチャネル抗体の測定法の開発
- Principal Investigator
  
  ARIMURA Kimiyoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
The effect of anti-ganglioside antibodies on ion channels
- Principal Investigator
  
  HIGUCHI Itsuro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Study on the new regulatory mechanisms of L-type calcium channelsPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Synergistic taste effectiveness of citric acid
- Principal Investigator
  
  HARADA Shuitsu
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Mechanism underlying the spontaneous changes in the cytosolic CaィイD12+ィエD1concentrations in rat adrenal chromaffin cells
- Principal Investigator
  
  SORIMACHI Masaru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
A new intracellular foctor for regulation of Ca channel.Principal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
The research for voltage-gated K+ channel abnormality in peripheral nerve disorders.
- Principal Investigator
  
  ARIMURA Kimiyoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Caチャネル調節機構の構造機能相関Principal Investigator
- Principal Investigator
  
  亀山正樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kagoshima University
The pathomechansim of Isaacs'syndrome.
- Principal Investigator
  
  ARIMURA Kimiyoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Estimation of Induced Eddy Current in the Brain and Characteristics of Nerve Excitation by Magnetic Stimulation
- Principal Investigator
  
  YUNOKUCHI Kazutomo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kagoshima University
Roles of calpastatin and ATP in regulation of the Ca channelPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Kagoshima University
Pathogenesis and pathophysiology of inherited carnitine deficiency using carnitine-deficient JVS mice
- Principal Investigator
  
  SAHEKI Takeyori
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
心筋イオンチャンネル
- Principal Investigator
  
  大地陸男
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
心筋イオンチャンネル
- Principal Investigator
  
  大地陸男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
Identification of endogenous calcium channel activator and develpment of clinical analysis method by spedific antibodies.
- Principal Investigator
  
  MAKI Masatoshi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  医学一般
- Research Institution
  KYOTO UNIVERSITY
カルシウムイオンの動員とその調節機構
- Principal Investigator
  
  栗山煕
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
心筋イオンチャンネル
- Principal Investigator
  
  大地陸男
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
Mechanisms of Regulation of Calcium ChannelsPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
  Hiroshima University
カルシウムイオンの動員とその調節機構
- Principal Investigator
  
  栗山煕
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Mechanisms of 'run-down' of calcium channelsPrincipal Investigator
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Okazaki National Research Institutes, National Inst. for Physiol. Sci.

All 2018 2017 2016 2015 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] A novel role of the antitumor agent tricyclodecan-9-yl-xanthogenate as an open channel blocker of KCNQ1/KCNE12018
- Author(s)
  Meikui Wu, Makoto Takemoto, Huan Luo, Jian-Jun Xu, Mei-Hong Lu, Masaki Kameyama, Toru Takumi, Wen-Jie Song
- Journal Title
  
  Eur J Pharmacol
  
  Volume : 824 Pages : 99-107
- DOI
  10.1016/j.ejphar.2018.02.013
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10218, KAKENHI-PUBLICLY-17H05749, KAKENHI-PROJECT-15K08181
[Journal Article] Calmodulin and ATP support activity of Cav1.2 channels by dynamic interactions2017
- Author(s)
  Minobe E, Mori MX, Kameyama M.
- Journal Title
  
  J Physiol
  
  Volume : 595 Pages : 2465-2477
- DOI
  10.1113/jp273736
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460296, KAKENHI-PROJECT-16K08499, KAKENHI-PROJECT-15K08181
[Journal Article] A new interaction between proximal and distal C-terminus of Cav1.2 channels.2017
- Author(s)
  Lyu L, Gao Q, Xu JJ, Minobe E, Zhu T, Kameyama M
- Journal Title
  
  J Pharmacol Sci
  
  Volume : 133 Pages : 240-246
- Acknowledgement Compliant / Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08181
[Journal Article] PKA and phosphatases attached to the CaV1.2 channel regulate channel activity in cell-free patches.2016
- Author(s)
  Xu JJ, Yu LF, Minobe E, Lu LT, Lei M, Kameyama M
- Journal Title
  
  American Journal of Physiology Cell Physiology
  
  Volume : 310
- DOI
  10.1152/ajpcell.00157.2015
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08181, KAKENHI-PROJECT-25460294
[Journal Article] Mg2+-dependent facilitation and inactivation of L-type Ca2+ channel in guinea pig ventricular myocytes.2015
- Author(s)
  Zhao MM, Feng R, Shao DX, Liu SY, Lei M, Wang HM, Sun XF, Guo F, Hu HY, Kameyama M, Hao LY
- Journal Title
  
  J Pharmacol Sci
  
  Volume : 129 Pages : 143-149
- DOI
  10.1016/j.jphs.2015.08.001
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08181
[Journal Article] Regulation of the Cav1.2 cardiac channel by redox via modulation of CaM interaction with the channel.2015
- Author(s)
  Sun Y, Xu JJ, Minobe E, Shimoara S, Hao LY, Kameyama M
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume : 128 Pages : 137-143
- DOI
  10.1016/j.jphs.2015.06.003
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08181, KAKENHI-PROJECT-25460294
[Journal Article] Nucleotides maintain the activity of Cav1.2 channels in guinea-pig ventricular myocytes.2015
- Author(s)
  Liu SY, Xu JJ, Minobe E, Gao QH, Feng R, Zhao MM, Guo F, Yang L, Kameyama M, Hao LY
- Journal Title
  
  Biochemical and Biophysical Research Communication
  
  Volume : 460 Pages : 813-818
- DOI
  10.1016/j.bbrc.2015.03.111
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08181, KAKENHI-PROJECT-25460294
[Journal Article] Cloning and expression of the two new variants of Nav1.5/SCN5A in rat brain2012
- Author(s)
  Ren CT, Li DM, Ou SW, Wang YJ, Lin Y, Zong ZH, Kameyama M, Kameyama A
- Journal Title
  
  Mol.Cell.Biochem.
  
  Volume : (In press)
- DOI
  10.1007/s11010-012-1253-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390059
[Journal Article] Calpastatin domain L is a partial agonist of the calmodulin-binding site for channel activation in Cav12011
- Author(s)
  Minobe E, Asmara H, Saud ZA, and Kameyama M.
- Journal Title
  
  J Biol Chem
  
  Volume : 286(45) Pages : 39013-39022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390059
[Journal Article] Calpastatin domain L is a partial agonist of the calmodulin-binding site for channel activation in Cav1.2 Ca2+ channels.2011
- Author(s)
  Minobe E, Asmara H, Saud ZA, Kameyama M
- Journal Title
  
  The journal of biochemistry
  
  Volume : 286 Pages : 39013-39022
- DOI
  10.1074/jbc.m111.242248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390059, KAKENHI-PROJECT-23790251
[Journal Article] Calmodulin-and Ca^<2+>-dependent facilitation and inactivation of the CaV1. 2 Ca^<2+> channels in guinea-pig ventricular myocytes2010
- Author(s)
  Han DY, Minobe E, Wang WY, Guo F, Xu JJ, Hao LY, Kameyama M.
- Journal Title
  
  J Pharmacol Sci
  
  Volume : 112(3) Pages : 310-319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390059
[Journal Article] Both N-and C-lobes of calmodulin are required for Ca^<2+>-dependent regulations of CaV1. 2 Ca^<2+> channels2010
- Author(s)
  Guo F, Minobe E, Yazawa K, Asmara H, Bai XY, Han DY, Hao LY and Kameyama M.
- Journal Title
  
  Biochem Biophys Res Comm
  
  Volume : 391(2) Pages : 1170-1176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390059
[Journal Article] Interactions of calmodulin with the multiple binding sites of Cav1. 2 Ca^<2+> channels2010
- Author(s)
  Asmara H, Minobe E, Saud ZA, Kameyama M.
- Journal Title
  
  J Pharmacol Sci
  
  Volume : 112(4) Pages : 397-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390059
[Journal Article] CaMKII phosphorylates a threonine residue in the C-terminal tail of Cav1. 2 Ca^<2+> channel and modulates the interaction of the channel with calmodulin2009
- Author(s)
  Wang WY, Hao LY, Minobe E, Saud ZA, Han DY, Kameyama M.
- Journal Title
  
  J Physiol Sci
  
  Volume : 59(4) Pages : 283-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390059
[Journal Article] CaMKII phosphorylates a threonine residue in the C-terminal tail of Cav1.2 Ca^<2+> channel and modulates the interaction of the channel with calmodulin2009
- Author(s)
  Wang WY, Hao LY, Minobe E, Saud ZA, Han DY, Kameyama M
- Journal Title
  
  J Physiol Sci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Journal Article] The distinct roles of calmodulin and calmodulin kinase II in the reversal of run-down of L-type Ca^<2+> channels in guinea-pig ventricular myocytes2009
- Author(s)
  Hao LY, Wang WY, Minobe M, Han DY, Xu JJ, Kameyama A, Kameyama M.
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume : 111(4) Pages : 416-425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390059
[Journal Article] Calmodulin kinase II activation is required for the maintenance of basal activity of L-type Ca^<2+> channels in guinea-pig ventricular myocytes2008
- Author(s)
  Hao LY, Xu JJ, Minobe E, Kameyama A, Kameyama M
- Journal Title
  
  J Pharmacol Sci 108
  
  Pages : 290-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Journal Article] New variants of Nav1.5/SCN5A encode Na^+ channels in the brain2008
- Author(s)
  Wang J, Ou SW, Wang YJ, Zong ZH, Lin L, Kameyama M, Kameyama A
- Journal Title
  
  J Neurogenet 22(March)
  
  Pages : 1-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Journal Article] Calpastatin binds to a calmodulin-binding site of cardiac Cav1.2 Ca^<2+> channels2007
- Author(s)
  Saud ZA, Minobe E, Wang WY, Han DY, Horiuchi M, Hao LY, Kameyama M
- Journal Title
  
  Biochem Biophys Res Comm 364
  
  Pages : 372-377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Journal Article] (2007) Stonefish venom, verrucotoxin, modulates calcium channel activity in guinea-pig ventricular myocytes.2007
- Author(s)
  Yazawa K, Wang Jian-Wu, Hao Li-Ying, Onoue Y, Kameyama M.
- Journal Title
  
  British J Pharmacol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590189
[Journal Article] Distinct roles of CaM and Ca^<2+>/CaM- dependent protein kinase II in Ca^<2+>-dependent facilitation and inactivation of cardiac L-type Ca^<2+> channels.2007
- Author(s)
  Nie Hong-Guang, Hao Li-Ying, Xu Jian-Jun, Minobe E, Kameyama A, Kameyama M.
- Journal Title
  
  J Physiolo Sci (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590189
[Journal Article] Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M_3 receptor-PKC pathway2007
- Author(s)
  Wang JW, Yazawa K, Hao LY, Onoue Y, Kameyama M
- Journal Title
  
  Eur J Pharmacol 563
  
  Pages : 172-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Journal Article] Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway.2007
- Author(s)
  Wang Jian-Wu, Yazawa K, Hao Li-Ying, Onoue Y, Kameyama M.
- Journal Title
  
  Eur J Pharmacol 563
  
  Pages : 172-179
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590189
[Journal Article] Stonefish venom, verrucotoxin, modulates calcium channel activity in guinea-pig ventricular myocytes2007
- Author(s)
  Yazawa K, Wang JW, Hao LY, Onoue Y, Kameyama M
- Journal Title
  
  British J Pharmacol 151
  
  Pages : 1198-1203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Journal Article] Distinct roles of CaM and Ca^<2+>/CaM-dependent protein kinase II in Ca^<2+>-dependent facilitation and inactivation of cardiac L-type Ca^<2+> channels2007
- Author(s)
  Nie HG, Hao LY, Xu JJ, Minobe E, Kameyama A, Kameyama M
- Journal Title
  
  J Physiolo Sci 57
  
  Pages : 167-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Journal Article] A region of calpastatin domain L that reprimes cardiac L-type Ca2+ channels.2006
- Author(s)
  Minobe E, Hao LY, Saud ZA, Xu JJ, Kameyama A, Maki M, Jewell KK, Parr T, Bardsley RG, Kameyama M.
- Journal Title
  
  Biochem Biophys Res Commun. 348(1)
  
  Pages : 288-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590189
[Journal Article] IgM-containing fraction suppressed voltage-gated potassium channels in acquired neuromyotonia.2006
- Author(s)
  Kurono A, Arimura K, Watanabe O, Tomimitsu H, Nagado T, Sonoda Y, Kameyama M, Osame M.
- Journal Title
  
  Acta Neurol Scand. 113(3)
  
  Pages : 185-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590189
[Journal Article] Tetrodotoxin-resistant Na^+ channels in human neuroblastoma cells are encoded by new variants of Nav1.5/SCN5A.2005
- Author(s)
  Ou SW, Kameyama A, Hao L, Horiuchi M, Minobe E, Wang WY, Makita N, Kameyama M
- Journal Title
  
  Eur J Neurosci 22
  
  Pages : 793-801
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590189
[Journal Article] IgM antibody suppressed voltage-gated potassium channels in acquired meuromyotonia.2005
- Author(s)
  Kurono A, Arimura K, Watanabe O, Tomimitsu H, Nagado T, Sonoda Y, Kameyama M, Ng A, Osame M.
- Journal Title
  
  Muscle Nerve (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590188
[Journal Article] Calmodulin reverses run-down of L-type Ca^<2+> channels in guinea-pig ventricular myocytes.2004
- Author(s)
  Xu JJ, Hao LY, Kameyama A, Kameyama M.
- Journal Title
  
  Am J Physiol (Cell Physiol) 287
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590188
[Journal Article] Mechanism of action of voltage-gated K^+ channel antibodies in acquired neuromyotonia.2004
- Author(s)
  Tomimitsu H, Arimura K, Nagado T, Watanabe O, Otsuka R, Kurono A, Sonoda Y, Osame M, Kameyama M.
- Journal Title
  
  Ann Neurol 56
  
  Pages : 440-444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590188
[Journal Article] Calmodulin reverses rundown of L-type Ca(2+) channels in guinea pig ventricular myocytes2004
- Author(s)
  Xu JJ, Hao LY, Kameyama A, Kameyama M.
- Journal Title
  
  Am J Physiol Cell Physiol 287
- Data Source
  KAKENHI-PROJECT-16590836
[Journal Article] Regulation of L-type Ca^<2+> channels in the heart : Overivew of recent advancements.2003
- Author(s)
  Yamaoka K, Kameyama M
- Journal Title
  
  J Mol Cell Biochem 253
  
  Pages : 3-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590188
[Presentation] Cav1.2型チャネルC末端の自己調節を基にしたPKAリン酸化のチャネル調節機序2018
- Author(s)
  高青華、雷明、徐建軍、蓑部悦子、朱曜南、ハオ麗英、亀山正樹
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] カルモジュリンとATPによるCav1.2チャネルの制御機構2018
- Author(s)
  蓑部悦子、森誠之、亀山正樹
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] Regulation of Cav1.2 channels by calmodulin: A study on genetically mutated channels2017
- Author(s)
  蓑部悦子、森誠之、亀山正樹
- Organizer
  第94回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] 神経細胞とCa2+チャネル2017
- Author(s)
  亀山正樹
- Organizer
  鹿児島神経科学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] The mechanism for PKA-mediated facilitation of Cav1.2 channel: A new model2017
- Author(s)
  呂力ティン, 高青華, 雷明, 徐建軍, 蓑部悦子, 亀山正樹.
- Organizer
  第94回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] Cav1.2 型Ca2+チャネルC 末端部におけるPKAリン酸化のチャネル活性調節機序2017
- Author(s)
  高青華、雷明、徐建軍、蓑部悦子、朱曜南、ハオ麗英、亀山正樹
- Organizer
  第68回西日本生理学会
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] Cav1.2型Ca2+チャネルC末端部のチャネル活性調節作用2016
- Author(s)
  高青華、徐建軍、呂力Ting、蓑部悦子、Hao麗英、亀山正樹
- Organizer
  第67回西日本生理学会
- Place of Presentation
  レインボー桜島（鹿児島県鹿児島市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] Cav1.2 channelの活性を調節する細胞内因子2016
- Author(s)
  亀山正樹
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] 2サイトモデルによるCav1.2チャネル調節の検討.2016
- Author(s)
  河路広大、蓑部悦子、森誠之、亀山正樹
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] Mechanism underlying PKA-mediated facilitation of cardiac Cav1.2 channels.2015
- Author(s)
  呂力Ｔｉｎｇ、雷　明、徐建軍、蓑部悦子、矢沢和人、亀山正樹
- Organizer
  第66回西日本生理学会
- Place of Presentation
  久留米大学（福岡県久留米市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] Cav1.2型チャネルC末端部切断変異体に対するカルモジュリンとATPの作用.2015
- Author(s)
  蓑部悦子、森誠之、亀山正樹
- Organizer
  第66回西日本生理学会
- Place of Presentation
  久留米大学（福岡県久留米市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K08181
[Presentation] Cav1. 2 Ca^<2+>チャネルC末端部には、複数の機能的Aキナーゼリン酸化部位がある2012
- Author(s)
  蓑部悦子、前田佐知子、徐建軍、はお麗英、封瑞、矢沢和人、亀山亜砂子、亀山正樹
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Cav1. 2 Ca^<2+>チャネルの活性調節におけるカルパスタチンとカルモジュリンの競合作用2012
- Author(s)
  蓑部悦子、Hadhimulya Asmara, Zahangir A. Saud, 亀山正樹
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] モルモット心室筋細胞におけるL型Ca^<2+>チャネルの過酸化水素による活性調節機構2012
- Author(s)
  楊磊、徐建軍、蓑部悦子、封瑞、亀山亜砂子、矢沢和人、亀山正樹
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] CaMKII-dependent and independent facilitation of L-type Ca^<2+> channels by hydrogen peroxide in guinea-pig ventricular myocytes2011
- Author(s)
  Yang L, Xu J-J, Minobe E, Feng R, Kameyama A, Yazawa K, Kameyama M.
- Organizer
  The 62th meeting of the Physiological Society of West Japan
- Place of Presentation
  Saga
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Effect of Ca^<2+> and calmodulin on activity of calmodulin-linked Cav1. 2 channel2011
- Author(s)
  Minobe E, Mori MX, Kameyama M.
- Organizer
  The 88th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Facilitation of L-type Ca^<2+> channels by hydrogen peroxide in guinea-pig ventricular myocytes2011
- Author(s)
  Yang L, Xu J-J, Minobe E, Feng R, Kameyama A, Yazawa K, Kameyama M.
- Organizer
  The 5th Biennial Meeting of Society for Free Radical Research(SFRR)-Asia and The 8th Conference of Asian Society for Mitochondrial Research and Medicine(ASMRM)
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Both PKA-mediated phosphorylation and calmodulin interaction are required for basal activity of cardiac L-type Ca^<2+> channel2011
- Author(s)
  Xu J-J, Saud ZA, Liu Y, Yang L, Minobe E, Kameyama A, Yazawa K, Hao L-Y, Kameyama M.
- Organizer
  The 88th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Roles of calmodulin and the C-terminal tail of Cav1. 2 channel in its activity2010
- Author(s)
  Minobe E, Mori MX, Kameyama M.
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Ca^<2+>-dependent modulation in calmodulin-linked Cav1. 2 channels2010
- Author(s)
  Minobe E, Mori MX, Xu J-J, Kameyama M.
- Organizer
  The 9th Japan-Korea Joint Symposium on Brain Sciences, and Cardiac and Smooth Muscles
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] PKA-mediated phosphorylation modulates the interaction of calmod ulin with cardiac Cav1. 2 channels2010
- Author(s)
  Xu J-J, Saud ZA, Liu Y, Yang L, Minobe E, Kameyama A, Yazawa K, Hao L-Y, Kameyama M.
- Organizer
  The 9th Japan-Korea Joint Symposium on Brain Sciences, and Cardiac and Smooth Muscles
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Multiple molecules of calmodulin bind to the Cav1. 2 Ca^<2+> channel2009
- Author(s)
  Asmara H, Minobe E, Saud ZA, Kameyama M.
- Organizer
  The 60th meeting of the Physiological Society of West Japan
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Calpastatin domain L competes with calmodulin on IQ region of Cav1. 2 channel2009
- Author(s)
  Minobe E, Saud ZA, Han D-Y, Asmara H, Wang W-Y, Hao L-Y, Kameyama M.
- Organizer
  The 36th International Congress of Physiological Sciences(IUPS2009)
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Ca^<2+> channels and cardiac functions. The 36th International2009
- Author(s)
  亀山正樹
- Organizer
  Congress of Physiological Sciences(IUPS2009)
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Ca^<2+> channels and cardiac functions2009
- Author(s)
  Kameyama M, Hao L-Y, Minobe E, Xu J-J, Han D-Y, Nie H-G, Saud ZA, Wang W-Y, Asmara H.
- Organizer
  The 36th International Congress of Physiological Sciences(IUPS2009)
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Multiple binding sites of calmodulin in the C-terminal tail of Cav1. 2 Ca^<2+> channel2009
- Author(s)
  Asmara H, Minobe E, Saud ZA, Wang W-Y, Kameyama M.
- Organizer
  The 36th International Congress of Physiological Sciences(IUPS2009)
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Regulation of Cav1.2 Ca^<2+> channels by Ca^<2+>, calmodulin and CaMKII2009
- Author(s)
  亀山正樹
- Organizer
  IUPS Satellite Symposium on Ion channels : function, structure and physiology
- Place of Presentation
  Hiei/Kyoto
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Regulation of Cav1. 2 Ca^<2+> channels by Ca^<2+>, calmodulin and CaMKII2009
- Author(s)
  Kameyama M, Hao L-Y, Minobe E, Xu J-J, Han D-Y, Nie H-G, Saud ZA, Wang W-Y, Asmara H, Yazawa K.
- Organizer
  IUPS Satellite Symposium on Ion channels : function, structure and physiology
- Place of Presentation
  Hiei/Kyoto
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] カルモジュリンの心筋Ca^<2+>チャネル(Cav1.2)に対する二重作用2009
- Author(s)
  亀山正樹
- Organizer
  生理学研究所研究会
- Place of Presentation
  岡崎市(愛知県)
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Cav1.2 Ca^<2+>チャネルのCaM による調節機構熱処理はPKA活性化を介して心筋細胞L型Ca2+電流を増大させる2008
- Author(s)
  郭鳳、蓑部悦子、矢沢和人、Asmara H、韓冬雲、はお麗英、亀山正樹
- Organizer
  生理学研究所研究会
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] 熱処理はPKA活性化を介して心筋細胞L型Ca^<2+>電流を増大させる2008
- Author(s)
  王建武、矢沢和人、Zahangir A. Saud、山岡薫、亀山正樹
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] L型Caチャネルの生理と心筋機能2008
- Author(s)
  亀山正樹
- Organizer
  東京慈恵会医科大学第1回分子循環器セミナー
- Place of Presentation
  東京
- Year and Date
  2008-12-17
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] Functional phosphorylation sites for modulation by protein kinase A in Cav1.2 Ca^<2+> channels2008
- Author(s)
  蓑部悦子、前田佐知子、はお麗英、王午陽、徐建軍、亀山正樹
- Organizer
  第85回日本生理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] Interactions of N- and C-lobes of calmodulin with the C-terminal tail of Cav1.2 Ca^<2+> channels2008
- Author(s)
  Asmara H, Minobe M, Saud ZA, Wang WY, Kameyama M
- Organizer
  第85回日本生理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] 心筋Caチャネルの調節機構2008
- Author(s)
  亀山正樹
- Organizer
  第11回札幌高血圧セミナー
- Place of Presentation
  札幌
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] Calciumand concentration-dependent effects of calmodulin and its mutants on CaV1.2 Ca^<2+> channels in guinea pig ventricular myocytes2008
- Author(s)
  Guo F, Minobe E, Yazawa K, Asmara H, Han DY, Hao LY, Kameyama M
- Organizer
  第59回西日本生理学会
- Place of Presentation
  熊本
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] Distinct roles of CaM and Ca^<2+>/CaM-dependent protein kinase in Ca^<2+>-dependent facilitation and inactivation of cardiac L-type Ca^<2+> channels2008
- Author(s)
  Nie HG, Hao LY, Xu JJ, Minobe E, Kameyama A, Kameyama M
- Organizer
  第85回日本生理学会(JPS Award Symposium)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] 心筋L型Caチャネルのカルモジュリンによる調節2007
- Author(s)
  亀山正樹、韓冬雲、蓑部悦子、王午陽、聶宏光、はお麗英
- Organizer
  第24回日本心電学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] L型Caチャネルの活動調節におけるカルパスタチンとカルモジュリンの競合2007
- Author(s)
  蓑部悦子、韓冬雲、Zahangir A. Saud、王午陽、はお麗英、亀山正樹
- Organizer
  第58回西日本生理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] Regulation of cardiac L-type Ca^<2+> channels by calmodulin and CaMKII2007
- Author(s)
  Kameyama M, Hao LY, Han DY, Minobe E, Wang WY, Nie HG, Saud ZA
- Organizer
  Akita International Symposium
- Place of Presentation
  Akita
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] Cav1.2チャネルのカルモジュリンおよびCa依存性調節2007
- Author(s)
  亀山正樹、韓冬雲、蓑部悦子、王午陽、はお麗英
- Organizer
  生理学研究所研究会
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-19590210

1. KAMEYAMA Asako (70244225)

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2. HAO Li-ying (40311881)

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# of Collaborated Projects : 1results

# of Collaborated Products : 0results
36. 浦本裕之 (50253860)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
37. WANG Wu-yang

# of Collaborated Projects : 1results

# of Collaborated Products : 12results
38. NIE Hong-guang

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
39. HAN Dong-yun

# of Collaborated Projects : 1results

# of Collaborated Products : 9results
40. BAI Xiao-yan

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
41. GUO Feng

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
42. LIE Yan

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
43. OKADA Hiromu

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
44. MORI Tomoyuki

# of Collaborated Projects : 1results

# of Collaborated Products : 6results
45. HAO Liying

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
46. ZHU Tong

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
47. LYU Liting

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
48. LEI Ming

# of Collaborated Projects : 1results

# of Collaborated Products : 6results
49. SAUD ZAHANGIR A.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
50. 〓〓英

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
51. HAO L-Ying

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
52. Mori Yasuo

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
53. 竹本誠

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
54. 宋文杰

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

Kameyama Masaki 亀山 正樹

亀山 正樹 カメヤマ マサキ

KAMEYAMA Masaki 亀山 正樹

Research Projects

Research Products

Co-Researchers

Molecular mechanism of self-regulation of Cav1.2 channel by channel cytoplasmic fragmentsOngoing

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Study on the regulatory mechanisms of L-type Ca2+ channelsPrincipal Investigator

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An interrelation among regulatory mechanisms of cardiac Ca2+channelsPrincipal Investigator

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Molecular mechanisms underlying Ca2^<+>-dependent facilitation and inactivation of L-type Ca^<2+> channelsPrincipal Investigator

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Molecular mechanisms of regulation of L-type Ca channelsPrincipal Investigator

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Complexity of the regulation of L-type calcium channelsPrincipal Investigator

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Mechanisms for regulation of L-type Ca channels by intracellular factorsPrincipal Investigator

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Study on the new regulatory mechanisms of L-type calcium channelsPrincipal Investigator

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A new intracellular foctor for regulation of Ca channel.Principal Investigator

Kameyama Masaki 亀山正樹

亀山正樹カメヤママサキ

KAMEYAMA Masaki 亀山正樹