YAZAWA Kazuto 矢沢和人

… Alternative Names

矢澤和人ヤザワカズト

矢沢和人ヤザワカズト

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Researcher Number	90212274
Other IDs
Affiliation (based on the past Project Information) *help	2011: 鹿児島大学, 大学院・医歯学総合研究科, 講師 2010: 鹿児島大学, 医歯学総合研究科, 講師 2007 – 2009: 鹿児島大学, 大学院・医歯学総合研究科, 講師 2006: Kagoshima Univ., Graduate School of Medical and Dental Sciences, Assistant Professor, 大学院医歯学総合研究科, 講師 2003 – 2005: 鹿児島大学, 大学院・医歯学総合研究科, 講師 … More 2002: Kagoshima University, Faculty of Medicine, Assistant Professor, 医学部, 講師 1999 – 2001: School of Medicine, akita Univeersity, Lecturer, 医学部, 講師 1998: 旭川医科大学, 医学部, 助手 1994: Asahikawa Medical College, School of Medicine, Assistant, 医学部・薬理学講座, 助手 1989 – 1993: 旭川医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General pharmacology Except Principal Investigator General pharmacology / General physiology / General physiology
Keywords	Principal Investigator カルシウム電流 / リゾ燐脂質 / 心室筋 / パッチクランプ法 / モルモット / バッチクランプ法 / calcium current / lysophosphatidylcholine / ventricular myocytes / patch clamp method / guinea-pig … More Except Principal Investigator … More 心筋細胞 / Caチャネル / パッチクランプ / カルモジュリン / patch clamp / 心筋 / veratridine / 細胞内Ca^<2+>濃度 / TRPC4 / cardiac myocyte / calmodulin / 虚血 / ジルチアゼム / カルシウムチャネル / ATP / ラット / ランゲンドルフ / 低酸素 / マグネシウム / カルモジュリン依存性蛋白キナーゼ / CST融合淡白 / 生体膜 / チャネル / シグナル伝達 / リン酸化 / トランスポーター / 能動輸送 / 細胞内カルシウム濃度 / fura-2 / カルシウムパラドックス / β-遮断薬 / ベラトリジン / ベラトソジン / カルシウムイオン / カルシウム拮抗薬 / β‐遮断薬 / Intracellular calcium concentration / Cardiac myocytes / Fura-2 / Calcium paradox / beta-adrenoceptor blockers / 活性酸素 / 過酸化水素 / lysophosphatidylcholine / d-propranolol / dilazep / 虚血・再潅流障害 / ラット心室筋細胞 / [Ca^<2+>]_<in> / Na^+チャネル / propranolol / リドカイン / OXYGEN RADICAL / HYDROGEN PEROXIDE / INTRACELLULAR CALCIUM / LYSOPHOPHATIDYLCHOLINE / d-PROPRANOLOL / DILAZEP / 大動脈内皮細胞 / 膜電位固定 / 細胞膜Ca^<2+> ATPase / アンチセンス / 容量性Ca^<2+>流入 / cl^-チャネル / Cl^-チャネル / TRPC4バリアント / HEK-293細胞 / 細胞膜Ca^<2+>ATPase / TRP4 / human aortic endothelial cells / voltage clamp / intracellular Ca^<2+> concentration / Ca^<2+> ATPase / antisense / capacitative Ca^<2+> entry / Cl^- channel / イオンチャネル / Caチャンネル / イオンチャンネル / Calcium channel / ion channel / カルパスタチン / rundown / Ca channels / calpastatin / カルモジュリン依存性キナーゼ / GST融合蛋白 / calcium channels / calmodulin kinase II / cardiac myocytes Less

An interrelation among regulatory mechanisms of cardiac Ca2+channels
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Molecular mechanisms underlying Ca2^<+>-dependent facilitation and inactivation of L-type Ca^<2+> channels
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Molecular mechanisms of regulation of L-type Ca channels
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Complexity of the regulation of L-type calcium channels
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Mechanisms for regulation of L-type Ca channels by intracellular factors
- Principal Investigator
  
  KAMEYAMA Masaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Molecular Pharmacology of Capacitative Ca^<2+> Entry Channel of Human Aortic Endothelial Cell
- Principal Investigator
  
  IIJIMA Toshihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Akita University
Mechanism of metabolites produced by and protective drugs against ischemia-reperfusion injury in ventricular myocytes.Principal Investigator
- Principal Investigator
  
  YAZAWA Kazuto
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  AKITA UNIVERSITY
  Asahikawa Medical College
Pharmacological study on the derangements of myocardial cells induced by oxygen radicals, and protection from the derangements
- Principal Investigator
  
  ABIKO Yasushi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Asahikawa Medical College
The mechanism of inhibitory effects of antiischemic drugs on calcium paradox.
- Principal Investigator
  
  ABIKO Yasushi
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  ASAHIKAWA MEDICAL COLLEGE
薬物による虚血心筋保護のメカニズムに関する研究
- Principal Investigator
  
  ABIKO Yasushi (我孫子保)
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Asahikawa Medical College

All 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Both N-and C-lobes of calmodulin are required for Ca^<2+>-dependent regulations of CaV1. 2 Ca^<2+> channels2010
- Author(s)
  Guo F, Minobe E, Yazawa K, Asmara H, Bai XY, Han DY, Hao LY and Kameyama M.
- Journal Title
  
  Biochem Biophys Res Comm
  
  Volume: 391(2) Pages: 1170-1176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390059
[Journal Article] Stonefish venom, verrucotoxin, modulates calcium channel activity in guinea-pig ventricular myocytes.2007
- Author(s)
  矢澤和人
- Journal Title
  
  British J Pharmacol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590189
[Journal Article] Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway.2007
- Author(s)
  Wang Jian-Wu, Yazawa K, Hao Li-Ying, Onoue Y, Kameyama M.
- Journal Title
  
  Eur J Pharmacol 563
  
  Pages: 172-179
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590189
[Journal Article] (2007) Stonefish venom, verrucotoxin, modulates calcium channel activity in guinea-pig ventricular myocytes.2007
- Author(s)
  Yazawa K, Wang Jian-Wu, Hao Li-Ying, Onoue Y, Kameyama M.
- Journal Title
  
  British J Pharmacol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590189
[Journal Article] Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M_3 receptor-PKC pathway2007
- Author(s)
  Wang JW, Yazawa K, Hao LY, Onoue Y, Kameyama M
- Journal Title
  
  Eur J Pharmacol 563
  
  Pages: 172-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Journal Article] Stonefish venom, verrucotoxin, modulates calcium channel activity in guinea-pig ventricular myocytes2007
- Author(s)
  Yazawa K, Wang JW, Hao LY, Onoue Y, Kameyama M
- Journal Title
  
  British J Pharmacol 151
  
  Pages: 1198-1203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Journal Article] Stonefish venom, verrucotoxin, modulates calcium channel activity in guinea-pig ventricular myocytes.2007
- Author(s)
  Yazawa K.
- Journal Title
  
  British J Pharmacol 151
  
  Pages: 1198-1203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] モルモット心室筋細胞におけるL型Ca^<2+>チャネルの過酸化水素による活性調節機構2012
- Author(s)
  楊磊、徐建軍、蓑部悦子、封瑞、亀山亜砂子、矢沢和人、亀山正樹
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Cav1. 2 Ca^<2+>チャネルC末端部には、複数の機能的Aキナーゼリン酸化部位がある2012
- Author(s)
  蓑部悦子、前田佐知子、徐建軍、はお麗英、封瑞、矢沢和人、亀山亜砂子、亀山正樹
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Facilitation of L-type Ca^<2+> channels by hydrogen peroxide in guinea-pig ventricular myocytes2011
- Author(s)
  Yang L, Xu J-J, Minobe E, Feng R, Kameyama A, Yazawa K, Kameyama M.
- Organizer
  The 5th Biennial Meeting of Society for Free Radical Research(SFRR)-Asia and The 8th Conference of Asian Society for Mitochondrial Research and Medicine(ASMRM)
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] CaMKII-dependent and independent facilitation of L-type Ca^<2+> channels by hydrogen peroxide in guinea-pig ventricular myocytes2011
- Author(s)
  Yang L, Xu J-J, Minobe E, Feng R, Kameyama A, Yazawa K, Kameyama M.
- Organizer
  The 62th meeting of the Physiological Society of West Japan
- Place of Presentation
  Saga
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Both PKA-mediated phosphorylation and calmodulin interaction are required for basal activity of cardiac L-type Ca^<2+> channel2011
- Author(s)
  Xu J-J, Saud ZA, Liu Y, Yang L, Minobe E, Kameyama A, Yazawa K, Hao L-Y, Kameyama M.
- Organizer
  The 88th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] PKA-mediated phosphorylation modulates the interaction of calmod ulin with cardiac Cav1. 2 channels2010
- Author(s)
  Xu J-J, Saud ZA, Liu Y, Yang L, Minobe E, Kameyama A, Yazawa K, Hao L-Y, Kameyama M.
- Organizer
  The 9th Japan-Korea Joint Symposium on Brain Sciences, and Cardiac and Smooth Muscles
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Regulation of Cav1. 2 Ca^<2+> channels by Ca^<2+>, calmodulin and CaMKII2009
- Author(s)
  Kameyama M, Hao L-Y, Minobe E, Xu J-J, Han D-Y, Nie H-G, Saud ZA, Wang W-Y, Asmara H, Yazawa K.
- Organizer
  IUPS Satellite Symposium on Ion channels : function, structure and physiology
- Place of Presentation
  Hiei/Kyoto
- Data Source
  KAKENHI-PROJECT-21390059
[Presentation] Calciumand concentration-dependent effects of calmodulin and its mutants on CaV1.2 Ca^<2+> channels in guinea pig ventricular myocytes2008
- Author(s)
  Guo F, Minobe E, Yazawa K, Asmara H, Han DY, Hao LY, Kameyama M
- Organizer
  第59回西日本生理学会
- Place of Presentation
  熊本
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] Cav1.2 Ca^<2+>チャネルのCaM による調節機構熱処理はPKA活性化を介して心筋細胞L型Ca2+電流を増大させる2008
- Author(s)
  郭鳳、蓑部悦子、矢沢和人、Asmara H、韓冬雲、はお麗英、亀山正樹
- Organizer
  生理学研究所研究会
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-19590210
[Presentation] 熱処理はPKA活性化を介して心筋細胞L型Ca^<2+>電流を増大させる2008
- Author(s)
  王建武、矢沢和人、Zahangir A. Saud、山岡薫、亀山正樹
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590210

1. KAMEYAMA Masaki (60150059)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
2. HAO Li-ying (40311881)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. ABIKO Yasushi (90041821)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. HASHIZUME Hiroko (00154021)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KAMEYAMA Asako (70244225)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
6. MINOBE Etsuko (00448581)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
7. XU Jian-jun (10581689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
8. HARA Akiyoshi (90164988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IIJIMA Toshihiko (30004724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SATOH Eisaku (10282162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ONO Kyoichi (70185635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. WANG Wu-yang

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. NIE Hong-guang

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HAN Dong-yun

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. BAI Xiao-yan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. GUO Feng

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. LIE Yan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SAUD ZAHANGIR A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. はおり英

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

YAZAWA Kazuto 矢沢 和人

矢澤 和人 ヤザワ カズト

矢沢 和人 ヤザワ カズト

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Mechanism of metabolites produced by and protective drugs against ischemia-reperfusion injury in ventricular myocytes.Principal Investigator

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[Journal Article] Both N-and C-lobes of calmodulin are required for Ca^<2+>-dependent regulations of CaV1. 2 Ca^<2+> channels2010

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[Journal Article] Stonefish venom, verrucotoxin, modulates calcium channel activity in guinea-pig ventricular myocytes.2007

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[Journal Article] Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway.2007

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[Journal Article] (2007) Stonefish venom, verrucotoxin, modulates calcium channel activity in guinea-pig ventricular myocytes.2007

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[Journal Article] Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M_3 receptor-PKC pathway2007

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YAZAWA Kazuto 矢沢和人

矢澤和人ヤザワカズト

矢沢和人ヤザワカズト