Park Sam Yong 朴三用

… Alternative Names

PARK Sam-yong 朴三用

PAK Sam yong 朴三用

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Researcher Number	20291932
Other IDs	https://orcid.org/0000-0001-6164-8896
External Links
Affiliation (Current)	2024: 横浜市立大学, 生命医科学研究科, 教授
Affiliation (based on the past Project Information) *help	2012 – 2023: 横浜市立大学, 生命医科学研究科, 教授 2013: 横浜市立大学, 大学院医科学研究科, 教授 2009 – 2013: Yokohama City University, 生命ナノシステム科学研究科, 教授 2012: 横浜市立大学, 教授 2010: 横浜市立大学, 教授 … More 2007 – 2009: Yokohama City University, 国際総合科学研究科, 准教授 2008: 横浜市立大学, 国際総合科学研究, 准教授 2008: Yokohama City University, 生命ナノシステム科学研究科, 准教授 2005 – 2006: 横浜市立大学, 国際総合科学研究科, 準教授 2004: 横浜市立大学, 総合理学研究科, 助教授 2001 – 2002: 横浜市立大学, 大学院・総合理学研究科, 助教授 2001 – 2002: 横浜市立大学, 総合理学研究科, 助教授 1999 – 2000: 理化学研究所, 研究技術開発室, 研究員 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Basic Section 43040:Biophysics-related / Structural biochemistry / Complex systems Except Principal Investigator Structural biochemistry / Biophysics / Biological Sciences / Biophysics / Genetics/Genome dynamics / Living organism molecular science / Biological Sciences
Keywords	Principal Investigator 構造解析 / 光反応酵素 / 創薬 / RNAポリメラーゼ / インフルエンザ / 構造生物学 / X線結晶構造解析 / Nタンパク質 / 構造生物学研究 / Xタンパク質 … More / 新型コロナウイルス / cGMP光産生酵素 / 時分割解析 / X線自由電子レーザー / 光感受性タンパク質 / アデニル酸シクラーゼ / 光遺伝学 / 光活性化アデニル酸シクラーゼ / 抗体 / 構造我解析 / 複合体 / 抗生物質開発 / 一酸化窒素 / 情報伝達 / X線構造解析 / P450nor / チトクロムP450 / NO還元酵素 … More Except Principal Investigator X線結晶構造解析 / タンパク質 / XAFS / 感染症 / 宿主因子 / ウイルス / ヒストン / ヌクレオソーム / セントロメア / クロマチン / オートトランスポーター / 構造生物学 / SynGAP / Rap1b / シグナル伝達 / 結晶構造解析 / ポストゲノム / プロテオミクス / 数理科学 / 感染防御 / 共同研究インターンシップ / 許容性 / 宿主特異性 / 病原性発現 / 感染コンピテンシー / オミックス解析 / 数理科学解析 / 構造解析 / 自然免疫 / コンピテンシー / Sensor Protein / Copper (I) complex / Histidine kinase / Two-component system / Plant Hormone / Ethylene / 銅 / リン酸移転 / 二成分情報伝達系 / エチレン受容体 / センサータンパク質 / センサー蛋白質 / 銅(I)錯体 / ヒスチジンキナーゼ / 二成分系 / 植物ホルモン / エチレン / 分子生物学 / RNA依存性RNAポリメラーゼ / 転写 / ゲノム複製 / 小胞輸送 / 微小管 / エンドソーム / RNP / RNAポリメラーゼ / インフルエンザウイルス / ヒストンシャペロン / 染色体 / CENP-B / CENP-A / Ｘ線結晶構造解析 / ２状態モデル / 2状態モデル / 酸素平衡曲線 / アロステリー / ヘモグロビン / 細胞膜輸送 / 結晶 / 抗生剤 / 膜タンパク質 / ゲノム構造 / ゲノム機能 / ヒストンバリアント / 休眠打破 / タイマータンパク質 / 生物時計 / ガス状シグナル分子 / 酸素化型ヘム / alky1 isocyanide / EXAFS / 一酸化窒素(NO) / YC-1 / 5配位高スピン型 / アジド / ヘム鉄 / 低分子シグナル分子 / ヌクレオチド / 可溶性グアニル酸シクラーゼ / 活性発現の分子機構 / 蛋白質 / 生物物理 / 蛋白質間相互作用 / 膜蛋白質 / 膜輸送 Less

Structure and functional analysis of the SARS-CoV-2 Nucleocapsid ProteinPrincipal Investigator
- Principal Investigator
  
  朴三用
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Yokohama City University
Structural analysis of various light-driven reaction mechanisms of light-sensitive proteins.Principal Investigator
- Principal Investigator
  
  朴三用
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Yokohama City University
Molecular mechanism of photoactivation of a light-regulated adenylate cyclasePrincipal Investigator
- Principal Investigator
  
  Park Sam-Yong
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Yokohama City University
Structural Study on Mental Disease Gene Product Protein
- Principal Investigator
  
  UNZAI Satoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Hosei University
  Yokohama City University
The mechanism analysis of influenza RNA polymerasePrincipal Investigator
- Principal Investigator
  
  Park Sam-Yong
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University
Host cell competnecy for negative-stranded RNA viruses
- Principal Investigator
  
  NAGATA Kyosuke
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Molecular basis of host cell competency in virus infection
- Principal Investigator
  
  NAGATA Kyosuke
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Structural Study on neuron protein complex essential for memory and learning
- Principal Investigator
  
  UNZAI Satoru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University
Elucidation of the true picture of the hemoglobin allosteric equilibrium
- Principal Investigator
  
  SHIBAYAMA Naoya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
Analyses of centromeric chromatin structure
- Principal Investigator
  
  TACHIWANA Hiroaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Waseda University
Analysis of the outer membrane BAM complex
- Principal Investigator
  
  J・R・H Tame
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University
Structural basis for an essential subunit interaction in influenza virus RNA polymerase PB1-PB2Principal Investigator
- Principal Investigator
  
  PARK Sam-yong
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University
The structural analysis of centromere specific nucleosome
- Principal Investigator
  
  TACHIWANA Hiroaki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biophysics
- Research Institution
  Waseda University
タイマータンパク質EA4の計時機構解明を目指した研究
- Principal Investigator
  
  SHIBAYAMA Naoya
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
Structure and function of autotransporter proteins from pathogenic bacteria
- Principal Investigator
  
  TAME Jeremy R.H.
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University
Signal discrimination analyses based on the domain structure of soluble guanylate cyclase
- Principal Investigator
  
  MAKINO Ryu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Rikkyo University
Crystal structures of penicillin binding proteins from Haemophilus influenzaePrincipal Investigator
- Principal Investigator
  
  PARK Sam-yong
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University
膜結合型AAA-ATPase p47/p97複合体による細胞膜認識とその制御
- Principal Investigator
  
  TAME Jeremy R.H. (TAME J.R.H. / J・R・H Tame / JEREMY R・H Tame / JEREMY R.H.Tame)
- Project Period (FY)
  2003 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
NO標的酵素(可溶性グアニル酸シクラーゼー)のX線結晶構造解析Principal Investigator
- Principal Investigator
  
  朴三用
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University
Structural Analysis of Ethylene (Plant Hormone) Sensor Protein
- Principal Investigator
  
  SHIRO Yoshitsugu
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  The Institute of Physical and Chemical Research
一酸化窒素(NO)還元機構解明Principal Investigator
- Principal Investigator
  
  朴三用
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  The Institute of Physical and Chemical Research

[Book] 医学のあゆみ2015
- Author(s)
  朴三用
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-25291016
[Book] メディカル・トピックス:万能インフルエンザ治療薬に道筋2009
- Author(s)
  朴三用
- Total Pages
  1
- Publisher
  Newton 8月号
- Data Source
  KAKENHI-PROJECT-21370046
[Book] トピックス:万能インフルエンザ治療薬に道筋2009
- Author(s)
  朴三用
- Total Pages
  117
- Publisher
  メディカル
- Data Source
  KAKENHI-PROJECT-21370046
[Book] Dioxygen Binding and Sensing Proteins : A Tribute to Beatrice and Jonathan Wittenberg(編集 : Martino Bolognesi, Guido Di Prisco, Cinzia Verde, 出版社 : Springer)(ISBN 8847008069, 9788847008069)2008
- Author(s)
  Satoru Unzai, Kiyohiro Imai, Sam-Yong Park, Kiyoshi Nagai, and Jeremy R.H.
- Publisher
  Mutagenic studies on the Origins of the Root Effect
- Data Source
  KAKENHI-PROJECT-19370045
[Book] 「生命秩序を担う生体超分子」蛋白質核酸酵素増刊2005
- Author(s)
  雲財悟, 朴三用, Jeremy R.H.Tame
- Total Pages
  273
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface2022
- Author(s)
  Heo Yunseok、Ishimoto Naito、Jeon Ye-Eun、Yun Ji-Hye、Ohki Mio、Anraku Yuki、Sasaki Mina、Kita Shunsuke、Fukuhara Hideo、Ikuta Tatsuya、Kawakami Kouki、Inoue Asuka、Maenaka Katsumi、Tame Jeremy R. H.、Lee Weontae、Park Sam-Yong
- Journal Title
  
  PLOS Biology
  
  Volume: 20 Issue: 8 Pages: e3001714-e3001714
- DOI
  10.1371/journal.pbio.3001714
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-21H04791, KAKENHI-PROJECT-21H02449, KAKENHI-PLANNED-19H05779
[Journal Article] Structural insights into the HBV receptor and bile acid transporter NTCP2022
- Author(s)
  Park JH, Iwamoto M, Yun JH, Uchikubo-Kamo T, Son D, Jin Z, Yoshida H, Ohki M, Ishimoto N, Mizutani K, Oshima M, Muramatsu M, Wakita T, Shirouzu M, Liu K, Uemura T, Nomura N, Iwata S, Watashi K, Tame JRH, Nishizawa T, Lee W, Park SY.
- Journal Title
  
  Nature
  
  Volume: 606 Issue: 7916 Pages: 1027-1031
- DOI
  10.1038/s41586-022-04857-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15453, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-20H03216, KAKENHI-PROJECT-21H02449, KAKENHI-PROJECT-20K16264, KAKENHI-PLANNED-19H05779, KAKENHI-PLANNED-19H05777
[Journal Article] Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser.2021
- Author(s)
  MS, Liang M, Sierra RG, Lane TJ, Zhou L, Weierstall U, Zatsepin NA, Ohki M, Tame JRH, Park SY, Spence JCH, Zhang W, Schmidt M, Lee W, Liu H.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 118(13) Issue: 13 Pages: 1-9
- DOI
  10.1073/pnas.2020486118
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05779, KAKENHI-PROJECT-21H02449
[Journal Article] Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation.2021
- Author(s)
  Kim S, Yoon I, Son J, Park J, Kim K, Lee JH, Park SY, Kang BS, Han JM, Hwang KY, Kim S.
- Journal Title
  
  Cell Rep.
  
  Volume: 35(4) Issue: 4 Pages: 1-13
- DOI
  10.1016/j.celrep.2021.109031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05779, KAKENHI-PROJECT-21H02449
[Journal Article] Direct observation of ligand migration within human hemoglobin at work2020
- Author(s)
  Shibayama Naoya、Sato-Tomita Ayana、Ohki Mio、Ichiyanagi Kouhei、Park Sam-Yong
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 9 Pages: 4741-4748
- DOI
  10.1073/pnas.1913663117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06601, KAKENHI-PLANNED-17H06372, KAKENHI-WRAPUP-19H05451, KAKENHI-PROJECT-16K07326, KAKENHI-PLANNED-19H05779, KAKENHI-PROJECT-17H06141, KAKENHI-PROJECT-18H02413
[Journal Article] Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family2020
- Author(s)
  Yun Ji-Hye、Ohki Mio、Park Jae-Hyun、Ishimoto Naito、Sato-Tomita Ayana、Lee Wonbin、Jin Zeyu、Tame Jeremy R. H.、Shibayama Naoya、Park Sam-Yong、Lee Weontae
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 6 Pages: 6-6
- DOI
  10.1126/sciadv.aay2042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06601, KAKENHI-WRAPUP-19H05451, KAKENHI-PROJECT-16K07326, KAKENHI-PLANNED-19H05779, KAKENHI-PROJECT-18H02413
[Journal Article] Structure- Based Functional Modification Study of a Cyanobacterial Chloride Pump for Transporting Multiple Anions.2020
- Author(s)
  Yun JH, Park JH, Jin Z, Ohki M, Wang Y, Lupala CS, Liu H, Park SY*, Lee W*
- Journal Title
  
  J Mol Biol
  
  Volume: 432 Issue: 19 Pages: 5273-5286
- DOI
  10.1016/j.jmb.2020.07.016
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05779, KAKENHI-PROJECT-18H02413
[Journal Article] Epidermal growth factor receptor is a host entry cofactor triggering hepatitis B virus internalization2019
- Author(s)
  M. Iwamoto, W. Saso, R. Sugiyama, K. Ishii, M. Ohki, S. Nagamori, R. Suzuki, H. Aizaki, A. Ryo, J-H Yun, S-Y Park, N. Ohtani, M. Muramatsu, S. Iwami, Y. Tanaka, C. Sureau, T. Wakita and K. Watashi
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 116 Issue: 17 Pages: 8487-8492
- DOI
  10.1073/pnas.1811064116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05819, KAKENHI-PROJECT-16H04845, KAKENHI-PROJECT-18H01139, KAKENHI-PROJECT-16KT0111, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-15KT0107, KAKENHI-PROJECT-16K08825, KAKENHI-PROJECT-16K13777, KAKENHI-PROJECT-19K16672, KAKENHI-PROJECT-18H02413, KAKENHI-PROJECT-19J21455, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
[Journal Article] Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide.2018
- Author(s)
  Kaneko M, Futamura Y, Tsukuda S, Kondoh Y, Sekine T, Hirano H, Fukano K, Ohashi H, Saso W, Morishita R, Matsunaga S, Kawai F, Ryo A, Park SY, Suzuki R, Aizaki H, Ohtani N, Sureau C, Wakita T, Osada H, Watashi K.
- Journal Title
  
  Sci Rep.
  
  Volume: 2769 Pages: 1-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02413
[Journal Article] Crystal structure of the Ube2K/E2-25K and K48-linked di-ubiquitin complex provides structural insight into the mechanism of K48-specific tri-ubiquitin synthesis2018
- Author(s)
  J. G. Lee, H. S. Youn, J. Y. Kang, S. Y. Park, A. Kidera, Y. J. Yoo, and S. H. Eom
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 506 Issue: 1 Pages: 102-107
- DOI
  10.1016/j.bbrc.2018.10.067
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04780, KAKENHI-PROJECT-18H02413, KAKENHI-PROJECT-16K14714
[Journal Article] Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency2018
- Author(s)
  Yun Ji-Hye、Li Xuanxuan、Park Jae-Hyun、Wang Yang、Ohki Mio、Jin Zeyu、Lee Wonbin、Park Sam-Yong、Hu Hao、Li Chufeng、Zatsepin Nadia、Hunter Mark S.、Sierra Raymond G.、Koralek Jake、Yoon Chun Hong、Cho Hyun-Soo、Weierstall Uwe、Tang Leihan、Liu Haiguang、Lee Weontae
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 3 Pages: 794-804
- DOI
  10.1074/jbc.ra118.004038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15076, KAKENHI-PROJECT-18H02413, KAKENHI-PLANNED-19H05779
[Journal Article] Structural insights into a 20.8-kDa tegumental-allergen-like (TAL) protein from Clonorchis sinensis2017
- Author(s)
  Jo Chang Hwa、Son Jonghyeon、Kim Sulhee、Oda Takashi、Kim Jaehoon、Lee Myoung-Ro、Sato Mamoru、Kim Hyun Tae、Unzai Satoru、Park Sam-Yong、Hwang Kwang Yeon
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1764-1764
- DOI
  10.1038/s41598-017-02044-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06980
[Journal Article] Crystal structure of MytiLec, a galactose-binding lectin from the mussel Mytilus galloprovincialis with cytotoxicity against certain cancer cell types.2016
- Author(s)
  Terada D, Kawai F, Noguchi H, Unzai S, Hasan I, Fujii Y, Park SY, Ozeki Y, Tame JRH
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 28344-28344
- DOI
  10.1038/srep28344
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04779, KAKENHI-PROJECT-15K06980
[Journal Article] (9)Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacterium2016
- Author(s)
  Ohki M, Sugiyama K, Kawai F, Tanaka H, Nihei Y, Unzai S, Takebe M, Matsunaga S, Adachi S, Shibayama N, Zhou Z, Koyama R, Ikegaya Y, Takahashi T, Tame J, Iseki M, Park S-Y.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 113 Issue: 24 Pages: 6689-6664
- DOI
  10.1073/pnas.1517520113
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-26105001, KAKENHI-PROJECT-16H04779, KAKENHI-PROJECT-16J08137, KAKENHI-PROJECT-15K06980, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T
- Journal Title
  
  J Virol
  
  Volume: 89 Issue: 23 Pages: 11945-11953
- DOI
  10.1128/jvi.01855-15
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-ORGANIZER-24115001, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-15K07419, KAKENHI-PROJECT-25291016
[Journal Article] A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.2015
- Author(s)
  Yoshida H, Park S-Y, Oda T, Akiyoshi T, Sato M, Shirouzu M, Tsuda K, Kuwasako K, Unzai S, Muto Y, Urano T, Obayashi E.
- Journal Title
  
  Genes Dev.
  
  Volume: 29 Issue: 15 Pages: 1649-1660
- DOI
  10.1101/gad.267104.115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06980, KAKENHI-PROJECT-15K06982, KAKENHI-PROJECT-15K18499, KAKENHI-PUBLICLY-26116519, KAKENHI-PROJECT-25291016, KAKENHI-PROJECT-25291037
[Journal Article] The structure and conformational switching of Rap1B2015
- Author(s)
  H. Noguchi, T. Ikegami, A. Nagadoi, Y. O. Kamatari, S. Y. Park, J. R. H. Tame, S. Unzai
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 印刷中 Issue: 1 Pages: 46-51
- DOI
  10.1016/j.bbrc.2015.04.103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-15K06980, KAKENHI-PROJECT-15K07024, KAKENHI-PROJECT-25291016
[Journal Article] Structure-based analysis of domain function of chitin oligosaccharide deacetylase from Vibrio parahaemolyticus.2015
- Author(s)
  105.Hirano T, Sugiyama K, Sakaki Y, Hakamata W, Park SY, Nishio T.
- Journal Title
  
  FEBS Lett.
  
  Volume: 589(1) Issue: 1 Pages: 145-51
- DOI
  10.1016/j.febslet.2014.11.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25291016
[Journal Article] Capturing the Hemoglobin Allosteric Transition in a Single Crystal Form2014
- Author(s)
  Naoya Shibayama, Kanako Sugiyama, Jeremy R. H. Tame, and Sam-Yong Park.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 (13) Issue: 13 Pages: 5097-5105
- DOI
  10.1021/ja500380e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570197, KAKENHI-PROJECT-25291016
[Journal Article] The crystal structure of the active domain of Anopheles anti-platelet protein, a powerful anti-coagulant, in complex with an antibody.2014
- Author(s)
  Sugiyama, K., Iyori, M., Sawaguchi, A., Akashi, S., Tame, J.R.H., Park, S.-Y., Yoshida, S.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289 Issue: 23 Pages: 16303-16312
- DOI
  10.1074/jbc.m114.564526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-24659460, KAKENHI-PROJECT-25291016, KAKENHI-PROJECT-25305007, KAKENHI-PROJECT-26860278
[Journal Article] Computational design of a self-assembling symmetrical β-propeller protein.2014
- Author(s)
  Voet AR, Noguchi H, Addy C, Simoncini D, Terada D, Unzai S, Park SY, Zhang KY, Tame JR.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 111 Issue: 42 Pages: 145-151
- DOI
  10.1073/pnas.1412768111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25291016
[Journal Article] The structure of the deacetylase domain of Escherichia coli PgaB, an enzyme required for biofilm formation: a circularly permuted member of the carbohydrate esterase 4 family.2013
- Author(s)
  Nishiyama, T., Noguchi, H., Yoshida, H., Park, S. Y. & Tame, J. R. H.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr
  
  Volume: 69 Issue: 1 Pages: 44-51
- DOI
  10.1107/s0907444912042059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] The structure of the deacetylase domain of Escherichia coli PgaB, an enzyme required for biofilm formation: a circularly permuted member of the carbohydrate esterase 4 family2013
- Author(s)
  Nishiyama, T., Noguchi, H., Yoshida, H., Park, S. Y. & Tame, J. R. H
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr
  
  Volume: 69 Pages: 44-51
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] Insight into structural diversity of influenza virus haemagglutinin2013
- Author(s)
  Cho, K. J., Lee, J.-H., Hong, K. W., Kim, S.-H., Park, Y., Lee, J. Y., Kang, S., Kim, S., Yang, J. H., Kim, E.-K., Seok, J. H., Unzai, S., Park, S.-Y., Saelens, X., Kim, C.-J., Lee, J.-Y., Kang, C., Oh, H.-B., Chung, M. S., and Kim, K. H.
- Journal Title
  
  J. Gen. Virol.
  
  Volume: 94
- Data Source
  KAKENHI-PROJECT-23570145
[Journal Article] Homopiperazine Derivatives as a Novel Class of Proteasome Inhibitors with a Unique Mode of Proteasome Binding.2013
- Author(s)
  Kikuchi J.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e60649-e60649
- DOI
  10.1371/journal.pone.0060649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591047, KAKENHI-PROJECT-23591405, KAKENHI-PROJECT-23791089, KAKENHI-PROJECT-25291016, KAKENHI-PUBLICLY-23118524
[Journal Article] Insight into structural diversity of influenza virus hemagglutinin.2013
- Author(s)
  Ki Joon Cho, et al.
- Journal Title
  
  Journal of General Virology
  
  Volume: 94 Issue: 8 Pages: 1712-1722
- DOI
  10.1099/vir.0.051136-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570145, KAKENHI-PROJECT-25291016
[Journal Article] Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle2012
- Author(s)
  Hansman, G. S., Taylor, D. W., McLellan,J. S., Smith, T. J., Georgiev, I., Tame, J. R. H., Park, S. Y., Yamazaki, M., Gondaira, F., Miki, M., Katayama, K., Murata, K. & Kwong, P. D
- Journal Title
  
  J Virol
  
  Volume: 86 Pages: 3635-46
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] Structures of haemoglobin from woolly mammoth in liganded and unliganded states2012
- Author(s)
  Noguchi, H., Campbell, K. L., Ho, C., Unzai, S., Park, S. Y. & Tame, J. R. H
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr
  
  Volume: 68 Pages: 1441-9
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] Crystal structures of penicillin-binding protein 3 (PBP3) from methicillin-resistant Staphylococcus aureus in the apo and cefotaxime-bound forms2012
- Author(s)
  Yoshida H, Kawai F, Obayashi E, Akashi S, Roper DI, Tame JR, Park SY
- Journal Title
  
  J Mol Biol
  
  Volume: 423 Issue: 3 Pages: 351-364
- DOI
  10.1016/j.jmb.2012.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227009, KAKENHI-PROJECT-22370044, KAKENHI-PROJECT-22570120, KAKENHI-PROJECT-23570143, KAKENHI-PLANNED-21113003, KAKENHI-PUBLICLY-23112717
[Journal Article] Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle2012
- Author(s)
  Hansman, G.S., Taylor, D.W., McLellan, J.S., Smith, T.J., Georgiev, I., Tame, J.R., Park, S.Y., Yamazaki, M., Gondaira, F., Miki, M., Katayama, K., Murata, K., Kwong, P.D.
- Journal Title
  
  Journal of Virology
  
  Volume: 86(7) Issue: 7 Pages: 3635-3646
- DOI
  10.1128/jvi.06868-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] Crystal structures of penicillin-binding protein 3 (PBP3) from methicillin-resistant Staphylococcus aureus in the apo and cefotaxime-bound forms2012
- Author(s)
  Yoshida, H., Kawai, F., Obayashi, E., Akashi, S., Roper, D. I., Tame, J. R. H. & Park, S. Y.
- Journal Title
  
  J Mol Biol
  
  Volume: 423 Pages: 351-64
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] Structures of haemoglobin from woolly mammoth in liganded and unliganded states.2012
- Author(s)
  Noguchi, H., Campbell, K. L., Ho, C., Unzai, S., Park, S. Y. & Tame, J. R. H.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr
  
  Volume: 412 Issue: 11 Pages: 551-2
- DOI
  10.1107/s0907444912029459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370044, KAKENHI-PROJECT-23570145
[Journal Article] Structures and oxygen affinities of crystalline human hemoglobin C (β6 Glu→Lys) in the R and R2 quaternary structures2011
- Author(s)
  Naoya Shibayama, Kanako Sugiyama, and Park Sam-Yong
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 33661-33668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570197
[Journal Article] Crystal structure of the human centromeric nucleosome containing CENP-A2011
- Author(s)
  Tachiwana H, Kagawa W, Shiga T, Osakabe A, Miya Y, Saito K, Hayashi-Takanaka Y, Oda T, Sato M, Park SY, Kimura H, Kurumizaka H
- Journal Title
  
  Nature
  
  Volume: 476 Issue: 7359 Pages: 232-235
- DOI
  10.1038/nature10258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J04280, KAKENHI-PROJECT-09J40035, KAKENHI-ORGANIZER-20114001, KAKENHI-PLANNED-21113002, KAKENHI-PROJECT-21370048, KAKENHI-PROJECT-21570196, KAKENHI-PUBLICLY-23114711, KAKENHI-PROJECT-23770008
[Journal Article] Structures and Oxygen Affinities of Crystalline Human Hemoglobin C (β6 Glu→Lys) in the R and R2 Quaternary Structures2011
- Author(s)
  Naoya Shibayama, Kanako Sugiyama, and Sam-Yong Park.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286(38) Issue: 38 Pages: 33661-33668
- DOI
  10.1074/jbc.m111.266056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570197
[Journal Article] Crystal structure of the human centromeric nucleosome containing CENP-A2011
- Author(s)
  Tachiwana H, Kagawa W, Shiga T, Osakabe A, Miya Y, Saito K, Hayashi-Takanaka Y, Oda T, Sato M, Park SY, Kimura H, Kurumizaka H.
- Journal Title
  
  Nature
  
  Volume: 476(7359) Pages: 232-5
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Structures and oxygen affinities of crystalline human hemoglobin C({beta} 6 Glu-> Lys) in the R and R2 quaternary structures2011
- Author(s)
  Shibayama N, Sugiyama K, Park SY
- Journal Title
  
  J Biol Chem
  
  Volume: 286(38) Pages: 33661-8
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Oxygen binding and redox properties of the heme in soluble guanylate cyclase : Implications for the mechanism of ligand discrimination2011
- Author(s)
  Makino R, Park SY, Obayashi E, Iizuka T, Hori H, Shiro Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 286(18) Pages: 15678-87
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Autotransporter passenger proteins : virulence factors with commonstructural themes.2010
- Author(s)
  Nishimura K, Tajima N, Yoon YH, Park SY, Tame JR.
- Journal Title
  
  J Mol Med
  
  Volume: 88 Pages: 451-8
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] 新規抗インフルエンザウイルス薬の開発基盤となるRNAポリメラーゼの構造解析2010
- Author(s)
  朴三用
- Journal Title
  
  生物物理
  
  Volume: Vol.50, No.2 Pages: 74-79
- NAID
  10025976244
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Crystal Structures of Penicillin-Binding Proteins 4 and 5 from Haemophilus influenzae.2010
- Author(s)
  Kawai F, Clarke TB, Roper DI, Han GJ, Hwang KY, Unzai S, Obayashi E, Park SY, Tame JR.
- Journal Title
  
  J Mol Biol
  
  Volume: 396 Pages: 634-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] Autotransporter passenger proteins : virulence factors with common structural themes2010
- Author(s)
  Nishimura K, Tajima N, Yoon YH, Park SY, Tame JR
- Journal Title
  
  J Mol Med
  
  Volume: 88(5) Pages: 451-8
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Direct determination of protonation states of histidine residues in a 2 A neutron structure of deoxy-human normal adult hemoglobin and implications for the Bohr effect2010
- Author(s)
  Kovalevsky AY, Chatake T, Shibayama N, Park SY, Ishikawa T, Mustyakimov M, Fisher Z, Langan P, Morimoto Y.
- Journal Title
  
  J Mol Biol
  
  Volume: 398(2) Pages: 276-91
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] A novel intein-like autoproteolytic mechanism in autotransporter proteins2010
- Author(s)
  Tajima, N., Kawai, F., Park, S. Y. & Tame, J. R. H
- Journal Title
  
  J Mol Biol
  
  Volume: 402 Pages: 645-56
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] インフルエンザウイルスRNAポリメラーゼの構造解析と創薬研究2010
- Author(s)
  杉山佳奈子、尾林栄治、吉田尚史、朴三用
- Journal Title
  
  日本結晶学会
  
  Volume: 52 Pages: 271-278
- NAID
  10027673105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] A novel intein-like autoproteolytic mechanism in autotransporter proteins2010
- Author(s)
  Tajima N, Kawai F, Park SY, Tame JR
- Journal Title
  
  J Mol Biol
  
  Volume: 402(4) Pages: 645-56
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Role of domains within the autotransporter Hbp/Tsh.2010
- Author(s)
  Nishimura K, Yoon YH, Kurihara A, Unzai S, Luirink J, Park SY, Tame JR.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr
  
  Volume: 66 Pages: 1295-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] Role of domains within the autotransporter Hbp/Tsh2010
- Author(s)
  Nishimura K, Yoon YH, Kurihara A, Unzai S, Luirink J, Park SY, Tame JR
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr
  
  Volume: 66(12) Pages: 1295-300
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] A Novel Intein-Like Autoproteolytic Mechanism in Autotransporter Proteins.2010
- Author(s)
  Tajima N, Kawai F, Park SY, Tame JR.
- Journal Title
  
  J Mol Biol
  
  Volume: 402 Pages: 645-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] インフルエザウスRNAポリメラーゼの構造解析と創薬研究2010
- Author(s)
  杉山佳奈子、尾林栄治、吉田尚史、朴三用
- Journal Title
  
  日本結晶学会
  
  Volume: 52 Pages: 271-278
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Autotransporter passenger proteins: virulence factors with common structural themes2010
- Author(s)
  Nishimura, K., Tajima, N., Yoon, Y. H., Park, S. Y. & Tame, J. R. H
- Journal Title
  
  J Mol Med
  
  Volume: 88 Pages: 451-8
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] タンパク質発現プロトコール2010
- Author(s)
  浅賀正充、朴三用
- Journal Title
  
  実験医学別冊(羊土社)
  
  Pages: 94-111
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Crystal Structures of Penicillin-Binding Proteins 4 and 5 from Haemophilus influenzae2010
- Author(s)
  Kawai F, Clarke TB, Roper DI, Han GJ, Hwang KY, Unzai S, Obayashi E, Park SY, Tame JR
- Journal Title
  
  J Mol Biol
  
  Volume: 396(3) Pages: 634-45
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Role of domains within the autotransporter Hbp/Tsh2010
- Author(s)
  Nishimura, K., Yoon, Y. H., Kurihara, A., Unzai, S., Luirink, J., Park, S. Y. & Tame, J. R. H
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr
  
  Volume: 66 Pages: 1295-300
- Data Source
  KAKENHI-PROJECT-22370044
[Journal Article] Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase2009
- Author(s)
  Sugiyama K, Obayashi E, Kawaguchi A, Suzuki Y, Tame JR, Nagata K, Park SY.
- Journal Title
  
  EMBO J
  
  Volume: 28(12) Pages: 1803-11
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Mutational Analysis of the Substrate Specificity of Escherichia coli Penicillin Binding Protein 4 (PBP4)2009
- Author(s)
  Clarke, T., Kawai, F., Park, S. Y., Tame, J., Dowson, C. & Roper, D.
- Journal Title
  
  Biochemistry 48
  
  Pages: 2675-2683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] 抗インフルエンザ薬の開発研究2009
- Author(s)
  朴三用
- Journal Title
  
  Bipphiliaビオフィリア(アドスリ社)
  
  Volume: 5(4) Pages: 25-29
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase2009
- Author(s)
  Sugiyama, K., Obayashi, E., Kawaguchi, A., Suzuki, Y., Tame, J. R., Nagata, K. & Park, S. Y.
- Journal Title
  
  Embo J., accepted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Mutational Analysis of the Substrate Specificity of Escherichia coli Penicillin Binding Protein 4(PBP4)2009
- Author(s)
  Clarke T, Kawai F, Park SY, Tame J, Dowson C, Roper D.
- Journal Title
  
  Biochemistry
  
  Volume: 48(12) Pages: 2675-83
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin2009
- Author(s)
  Tomita A, Sato T, Ichiyanagi K, Nozawa S, Ichikawa H, Chollet M, Kawai F, Park SY, Tsuduki T, Yamato T, Koshihara SY, Adachi SI
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 106(8) Pages: 2612-6
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] The nature of the TRAP-Anti-TRAP complex2009
- Author(s)
  Watanabe M, Heddle JG, Kikuchi K, Unzai S, Akashi S, Park SY, Tame JR
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 106(7) Pages: 2176-81
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] RNA and Protein Complexes of trp RNA-Binding Attenuation Protein Characterized by Mass Spectrometry2009
- Author(s)
  Akashi S, Watanabe M, Heddle JG, Unzai S, Park SY, Tame JR
- Journal Title
  
  Anal Chem
  
  Volume: 81(6) Pages: 2218-26
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] RNA and Protein Complexes of trp RNA-Binding Attenuation Protein Characterized by Mass Spectrometry2009
- Author(s)
  Akashi, S., Watanabe, M., Heddle, J. G., Unzai, S., Park, S. Y. & Tame, J. R.
- Journal Title
  
  Anal Chem 81
  
  Pages: 2218-2226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Structural Studies of a Bacterial Condensin Complex Reveal ATP-Dependent Disruption of Intersubunit Interactions2009
- Author(s)
  Woo JS, Lim JH, Shin HC, Suh MK, Ku B, Lee KH, Joo K, Robinson H, Lee J, Park SY, Ha NC, Oh BH.
- Journal Title
  
  Cell
  
  Volume: 136(1) Pages: 85-96
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] The nature of the TRAP-Anti-TRAP complex.2009
- Author(s)
  Watanabe M, Heddle JG, Kikuchi K, Unzai S, Akashi S, Park SY, Tame JR.
- Journal Title
  
  Proc Natl Acad Sci U S A. 106(7)
  
  Pages: 2176-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase2009
- Author(s)
  Sugiyama K, Obayashi E, Kawaguchi A, Suzuki Y, Tame JR, Nagata K, Park SY
- Journal Title
  
  EMBO J. 28(12)
  
  Pages: 286-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370046
[Journal Article] The nature of the TRAP-Anti-TRAP complex2009
- Author(s)
  Watanabe, M., Heddle, J. G., Kikuchi, K., Unzai, S., Akashi, S., Park, S. Y. & Tame, J. R.
- Journal Title
  
  Proc Natl Acad Sci U S A 106
  
  Pages: 2176-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] A Common Mechanism for the ATP-DnaA-dependent Formation of Open Complexes at the Replication Origin2008
- Author(s)
  Ozaki S, Kawakami H, Nakamura K, Fujikawa N, Kagawa W, Park SY, Yokoyama S, Kurumizaka H, Katayama T
- Journal Title
  
  J Biol Chem. 283(13)
  
  Pages: 8351-62
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] The structural basis for an essential subunit interaction in influenza virus RNA polymerase.2008
- Author(s)
  Obayashi E, Yoshida H, Kawai F, Shibayama N, Kawaguchi A, Nagata K, Tame JR, Park SY.
- Journal Title
  
  Nature 454(7208)
  
  Pages: 1127-31
- NAID
  10023987774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] The structural basis for an essential subunit interaction in influenza virus RNA polymerase2008
- Author(s)
  Obayashi, E., Yoshida, H., Kawai, F., Shibayama, N., Kawaguchi, A., Nagata, K., Tame, J. R. & Park, S. Y.
- Journal Title
  
  Nature 454
  
  Pages: 1127-31
- NAID
  10023987774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] The structural basis for an essential subunit interaction in influenza virus RNA polymerase2008
- Author(s)
  Obayashi E, Yoshida H, Kawai F, Shibayama N, Kawaguchi A, Nagata K, Tame JR, Park SY
- Journal Title
  
  Nature. 454(7208)
  
  Pages: 1127-31
- NAID
  10023987774
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Intersubunit linker length as a modifier of protein stability:crystal structures and thermostability of mutant TRAP2008
- Author(s)
  Watanabe M, Mishima Y, Yamashita I, Park SY, Tame JR, Heddle JG
- Journal Title
  
  Protin Sci. 17(3)
  
  Pages: 518-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Intersubunit linker length as a modifier of protein stability: crystal structures and thermostability of mutant TRAP.2008
- Author(s)
  Watanabe M, Mishima Y, Yamashita I, Park SY, Tame JR, Heddle JG.
- Journal Title
  
  Protein Sci. 17(3)
  
  Pages: 518-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Intersubunit linker length as a modifier of protein stability: crystal structures and thermostability of mutant TRAP.2008
- Author(s)
  Watanabe M, Mishima Y, Yamashita I, Park SY, Tame JR, Heddle JG.
- Journal Title
  
  Protein Sci. 17(3)
  
  Pages: 518-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Crystal structures of the clock protein EA4 from the silkworm Bombyx mori2008
- Author(s)
  Hiraki T, Shibayama N, Akashi S, Park SY
- Journal Title
  
  J Mol Biol. 377(3)
  
  Pages: 630-5
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Intersubunit linker length as a modifier of protein stability : crystal structures and thermostability of mutant TRAP.2008
- Author(s)
  Watanabe M, Mishima Y, Yamashita I, Park SY, Tame JR, Heddle JG.
- Journal Title
  
  Protein Sci. 17(3)
  
  Pages: 518-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Intersubunit linker length as a modifier of protein stability: crystal structures and thermostability of mutant TRAP2008
- Author(s)
  Watanabe, M., Mishima, Y., Yamashita, I., Park, S. Y., Tame, J. R. & Heddle, J. G.
- Journal Title
  
  Protein Sci 17
  
  Pages: 518-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Nickel binding to NikA : an additional binding site reconciles spectroscopy, calorimetry and crystallography.2007
- Author(s)
  Addy C, Chara M, Kawai F, Kidera A, Ikeguchi M, Fuchigami S, Osawa M, Shimada I, Park SY, Tame JR, Heddle JG
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr. 63(Pt 2)
  
  Pages: 221-229
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Effect of N-terminal residues on the structural stability of recombinant horse L-chain apoferritin in an acidic environment2007
- Author(s)
  Yoshizawa, K., Mishima, Y., Park, S. Y., Heddle, J. G., Tame, J. R., Iwahori, K., Kobayashi, M. & Yamashita, I.
- Journal Title
  
  J Biochem 142
  
  Pages: 707-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Effect of N-terminal residues on the structural stability of recombinant horse L-chain apoferritin in an acidic environment.2007
- Author(s)
  Yoshizawa K, Mishima Y, Park SY, Heddle JG, Tame JR, Iwahori K, Kobayashi M, Yamashita I.
- Journal Title
  
  J Biochem 142(6)
  
  Pages: 707-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Structure and mechanism of HpcG,a hydratase in the homoprotocatech uate degradation pathway of Escherichia coli2007
- Author(s)
  Izumi A, Rea D, Adachi T, Unzai S, Park SY, Roper DI, Tame JR
- Journal Title
  
  J Mol Biol 370(5)
  
  Pages: 899-911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Effect of N-terminal residues on the structural stability of recombinant horse L-chain apoferritin in an acidic environment.2007
- Author(s)
  Yoshizawa K, Mishima Y, Park SY, Heddle JG, Tame JR, Iwahori K, Kobayashi M, Yamashita I.
- Journal Title
  
  J Biochem 142(6)
  
  Pages: 707-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Nickel binding to NikA : an additional binding site reconciles spectroscopy, calorimetry and crystallography2007
- Author(s)
  Addy, C., Ohara, M., Kawai, F., Kidera, A., Ikeguchi, M., Fuchigami, S., Osawa, M., Shimada, I., Park, S. Y., Tame, J. R. & Heddle, J. G.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 63
  
  Pages: 221-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] EFFect of N-terminal reidues on the structural stability of recmbinant horse L-chain apoferritin in an acidic environment2007
- Author(s)
  Yoshizwa K, Mishima Y, Park SY, Heddle JG, Tame JR, Iwahori K, Kobayashi M, Yamashita I
- Journal Title
  
  J Biochem 142(6)
  
  Pages: 707-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Structure and mechanism of HpcG, a hydratase in the homoprotocatechuate degradation pathway of Escherichia coli.2007
- Author(s)
  Izumi A, Rea D, Adachi T, Unzai S, Park SY, Roper DI, Tame JR.
- Journal Title
  
  J Mol Biol. 370(5)
  
  Pages: 899-911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Dynamic allostery in the ring protein TRAP2007
- Author(s)
  Heddle, J. G., Okajima, T., Scott, D. J., Akashi, S., Park, S. Y. & Tame, J. R.
- Journal Title
  
  J Mol Biol 371
  
  Pages: 154-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Structure and mechanism of HpcG, a hydratase in the homoprotocatechuate degradation pathway of Escherichia coli2007
- Author(s)
  Izumi A, Rea D, Adachi T, Unzai S, Park SY, Roper DI, Tame JR
- Journal Title
  
  J Mol Biol. 370(5)
  
  Pages: 899-911
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Dynamic allostery in the ring protein TRAP.2007
- Author(s)
  Heddle JG, Okajima T, Scott DJ, Akashi S, Park SY, Tame JR.
- Journal Title
  
  J Mol Biol. 371(1)
  
  Pages: 154-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Structure and mechanism of HpcG, a hydratase in the homoprotocatechuate degradation pathway of Escherichia coli.2007
- Author(s)
  Izumi A, Rea D, Adachi T, Unzai S, Park SY, Roper DI, Tame JR.
- Journal Title
  
  J Mol Biol. 370(5)
  
  Pages: 899-911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Dynamic allostery in the ring protein TRAP2007
- Author(s)
  Heddle JG, Okajima T, Scott DJ, Akashi S, Park SY, Tame JR
- Journal Title
  
  J Mol Biol. 371(1)
  
  Pages: 154-67
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Crystallization and preliminary crystallographic studies of the metallogl ycoprotein esterase A4 using a baculovirus expression system.2007
- Author(s)
  Hiraki T, Shibayama N, Yoon YH, Yun KM, Hamamoto T, Tame JR, Park SY.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 9)
  
  Pages: 734-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Protonation States of Buried Histidine Residues in Human Deoxyhemoglobin Revealed by Neutron Crystallography2007
- Author(s)
  Chatake T, Shibayama N, Park SY, Kurihara K, Tamada T, Tanaka I, Niimura N, Kuroki R, Morimoto Y
- Journal Title
  
  J Am Chem Soc. 129(48)
  
  Pages: 14840-1
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Crystallication and preliminary crystallographic studies of the metallogl ycoprotein esterase A4 using a baculovirus expressio system2007
- Author(s)
  Hiraki T, Shibayama N, Yoon YH, Yun KM, Hamamoto T, Tame JR, Park SY
- Journal Title
  
  Acta Crystallogr sect F struct Biol Cryst Commun 63(Pt9)
  
  Pages: 734-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Crystallization and preliminary crystallographic studies of the metalloglycoprotein esterase A4 using a baculovirus expression system2007
- Author(s)
  Hiraki, T., Shibayama, N., Yoon, Y. H., Yun, K. M., Hamamoto, T., Tame, J. R. & Park, S. Y.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 63
  
  Pages: 734-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Structure and mechanism of HpcG, a hydratase in the homoprotocatechuate degradation pathway of Escherichia coli2007
- Author(s)
  Izumi, A., Rea, D., Adachi, T., Unzai, S., Park, S. Y., Roper, D. I. & Tame, J. R.
- Journal Title
  
  J Mol Biol 370
  
  Pages: 899-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370045
[Journal Article] Dynamic allostery in the ring protein TRAP.2007
- Author(s)
  Heddle JG, Okajima T, Scott DJ, Akashi S, Park SY, Tame JR.
- Journal Title
  
  J Mol Biol. 371(1)
  
  Pages: 154-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Crystallization and preliminary crystallographic studies of the metallogl ycoprotein esterase A4 using a baculovirus expression system.2007
- Author(s)
  Hiraki T, Shibayama N, Yoon YH, Yun KM, Hamamoto T, Tame JR, Park SY.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 9)
  
  Pages: 734-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570109
[Journal Article] Rounding up : Engineering 12-membered rings from the cyclic 11-mer TRAP.2006
- Author(s)
  Heddle JG, Yokoyama T, Yamashita I, Park SY, Tame JR
- Journal Title
  
  Structure. 14(5)
  
  Pages: 925-933
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Structural basis for protein recognition by B30.2/SPRY domains2006
- Author(s)
  J-S Woo, H-Y Suh, S-Y Park, B-H Oh
- Journal Title
  
  Mol. Cell 24
  
  Pages: 967-976
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Crystal Structure of penicillin Binding Protein4(dacB)from Escherichia coli, both in the Native Form and Covalently Linked to Various Antibiotics.2006
- Author(s)
  Kishida, H., Unzai, S., Roper, D.I., Lloyd, A., Park, S.Y., Tame, J.R.
- Journal Title
  
  Biochemistry 45(3)
  
  Pages: 783-792
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] 1.25 A resolution crystal structures of human haemoglobin in the oxy, deoxy and carbonmonoxy forms.2006
- Author(s)
  Park SY, Yokoyama T, Shibayama N, Shiro Y, Tame JR
- Journal Title
  
  J Mol Biol. 360(3)
  
  Pages: 690-701
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] R-state Haemoglobin with Low Oxygen Affinity : Crystal Structures of Deoxy Human and Carbonmonoxy Horse Haemoglobin Bound to the Effector Molecule L35.2006
- Author(s)
  Yokoyama, T., Neya, S., Tsuneshige, A., Yonetani, T., Park, S.Y., Tame, J.R.
- Journal Title
  
  Journal of Molecular Biology 356(3)
  
  Pages: 790-801
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Crystal structure of hemoglobin protease, a heme binding autotransporter protein from pathogenic Escherichia coli.2005
- Author(s)
  Otto, B.R., Sijbrandi, R., Luirink, J., Oudega, B., Heddle, J.G., Mizutani, K., Park, S.Y., Tame, J.R.
- Journal Title
  
  J.Biol.Chem. 280(17)
  
  Pages: 17339-17345
- Data Source
  KAKENHI-PROJECT-15083206
[Journal Article] Crystal structures of unliganded and half-liganded human hemoglobin derivatives cross-linked between Lys 82betal and Lys 82beta2.2004
- Author(s)
  Park, S.Y., et al.
- Journal Title
  
  Biochemistry 43(27)
  
  Pages: 87111-87117
- Data Source
  KAKENHI-PROJECT-15083206
[Patent] インフルエンザウイルスのRNA依存性RNAポリメラーゼのPB2サブユニットに対するモノクローナル抗体2014
- Inventor(s)
  朴三用、浦野健、杉山佳奈子
- Industrial Property Rights Holder
  朴三用、浦野健、杉山佳奈子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-068824
- Filing Date
  2014-03-28
- Acquisition Date
  2015-10-13
- Data Source
  KAKENHI-PROJECT-25291016
[Patent] インフルエンザウイルスのＲＮＡ依存性ＲＮＡポリメラーゼのＰＢ２サブユニットに対するモノクローナル抗体2014
- Inventor(s)
  朴三用、杉山佳奈子、成相裕子、浦野健
- Industrial Property Rights Holder
  朴三用、杉山佳奈子、成相裕子、浦野健
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-068824
- Filing Date
  2014-04-10
- Data Source
  KAKENHI-PROJECT-25291016
[Patent] インフルエンザウイルス由来のNAポリメラーゼ発現系構築と結晶化及び、抗インフルエンザ薬のスクリーニング方法2009
- Inventor(s)
  朴三用、尾林栄治、永田恭介、川口敦史
- Industrial Property Rights Holder
  公立大学法人横浜市立大学、国立大学法人筑波大学
- Filing Date
  2009-07-02
- Overseas
- Data Source
  KAKENHI-PROJECT-21370046
[Patent] 抗生剤として有効な新規化合物2008
- Inventor(s)
  朴三用
- Industrial Property Rights Holder
  横浜市立大学
- Filing Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-19570109
[Patent] 新規抗生剤の開発
- Inventor(s)
  朴三用
- Industrial Property Rights Holder
  横浜市立大学
- Industrial Property Number
  2008-213424
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] 光活性化アデニル酸シクラーゼの構造生物学的考察2020
- Author(s)
  大木規央、富田文菜、松永茂、伊関峰生、テイムジェレミー、柴山修哉、朴三用
- Organizer
  第４３回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02413
[Presentation] 光活性化アデニル酸シクラーゼの構造生物学的考察2020
- Author(s)
  大木規央、富田文菜、松永茂、伊関峰生、テイムジェレミー、柴山修哉、朴三用
- Organizer
  第４３回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05779
[Presentation] The structural basis for an essential subunit interaction in influenza virus RNA polymerase.2015
- Author(s)
  72.Hisashi Yoshida, Kanako Sugiyama, Mio Ohki, Sam-Yong Park.
- Organizer
  European crystallographic meeting.
- Place of Presentation
  Rovinj, Croatia.
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291016
[Presentation] シアノバクテリア由来の新規光活性化アデニル酸シクラーゼ2015
- Author(s)
  71.伊関峰生、二瓶悠樹、田中瞳、大木規央、杉山佳奈子、河合文啓、松永茂、高橋哲郎、朴三用
- Organizer
  第79回日本植物学会
- Place of Presentation
  新潟コンベンションセンター
- Year and Date
  2015-09-06
- Data Source
  KAKENHI-PROJECT-25291016
[Presentation] Structural and functional insights into a photoactivated adenylyl cyclase2015
- Author(s)
  73.Mio Ohki, Kanako Sugiyama, Fumihiro Kawai, Shigeru Matsunaga, Naoya Shibayama, Mineo Iseki, Sam-Yong Park.
- Organizer
  第53回日本生物物理学会
- Place of Presentation
  金沢大学
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-25291016
[Presentation] The structrue and conformational switching of Rap1b2015
- Author(s)
  Noguchi, H., Park, S.-Y. Tame, J.R.H., and Unzai, S.
- Organizer
  第53回生物物理学会年会
- Place of Presentation
  金沢大学
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-15K06980
[Presentation] 新規抗ウイルス薬の開発基盤となるRNAポリメラーゼの構造解析2013
- Author(s)
  朴三用
- Organizer
  CBI学会2013年大会 -生命医薬情報学連合大会-
- Place of Presentation
  タワーホール船堀
- Invited
- Data Source
  KAKENHI-PROJECT-25291016
[Presentation] Structural Studies of the Influenza RNA-polymerase for Novel Drug Design2013
- Author(s)
  Sam-Yong Park
- Organizer
  Meeting of the Italian, Spanish and Swiss crystallographic associations, MISSCA2013
- Place of Presentation
  Italty
- Invited
- Data Source
  KAKENHI-PROJECT-25291016
[Presentation] ヘモグロビンのアロステリック平衡のリアルな描像2012
- Author(s)
  柴山修哉, 朴三用
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学・東山キャンパス
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-23570197
[Presentation] リガンド結合状態及び非結合状態のケナガマンモスヘモグロビンの結晶構造2012
- Author(s)
  Hiroki Noguchi, Satoru Unzai, Kevin L. Campbell, Chien Ho, Sam-Yong Park, Jeremy R.H. Tame
- Organizer
  第50回日本生物物理学会年会　ポスター発表
- Place of Presentation
  名古屋大学東山キャンパス、愛知
- Data Source
  KAKENHI-PROJECT-23570145
[Presentation] Structural Studies of the Influenza RNA-polymerase for Novel Drug Design2011
- Author(s)
  Park SY
- Organizer
  The 9^<th> International Symposium for Future Drug Design and Medical Care
- Place of Presentation
  Hokkaido University(招待講演)
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] The structural and biochemical analyses of centromere specific nucleosome.2011
- Author(s)
  H.Tachiwana, W. Kagawa, T. Shiga, A. Osakabe, Y. Hayashi-Takanaka, S.Y. Park, H. Kimura, H. Kurumizaka
- Organizer
  EMBO conference series
- Place of Presentation
  EMBL Advanced Training Centre（ハイデルベルグ、ドイツ）
- Data Source
  KAKENHI-PROJECT-23770008
[Presentation] Structure of PB1-PB2 subunit interface of inflenza A virus RNA polymerase2011
- Author(s)
  Sugiyama K, Obayashi E, Kawaguchi A, Suzuki Y, Tame JR, Nagata K, Park SY
- Organizer
  IUCr
- Place of Presentation
  Palacio Municipal de Congresos. Madrid, Spain
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structural Studies of the Influenza RNA-polymerase for Novel Drug Design2011
- Author(s)
  Sam-Yong Park
- Organizer
  The 9^<th> International Symposium for Future Drug Design and Medical Care
- Place of Presentation
  Hokkaido University
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] The structural basis for the essential PA-PB1 subunit interaction in influenza RNA polymerase2011
- Author(s)
  Yoshida H, Obayashi E, Kawai F, Shibayama N, Kawaguchi A, Nagata K, Tame JR, Park SY
- Organizer
  IUCr
- Place of Presentation
  Palacio Municipal de Congresos. Madrid, Spain
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Crystal structure and biochemical property of the human centromere specific nucleosome.2011
- Author(s)
  H. Tachiwana, W. Kagawa, T. Shiga, R. Matsumoto, Y. Miya, A. Osakabe, Y. Hayashi-Takanaka, T. Oda, M. Sato, S.Y. Park, H. Kimura, H. Kurumizaka
- Organizer
  第34回　日本分子生物学会年会（招待講演）(招待講演)
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23770008
[Presentation] セントロメア特異的なヌクレオソームの構造・生化学・細胞生物学的解析2011
- Author(s)
  立和名　博昭、香川　亘、志賀達也、越阪部　晃永、宮　優太、松本亮平、林　陽子、朴　三用、木村　宏、胡桃坂　仁志
- Organizer
  第84回　日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-23770008
[Presentation] インフルエンザRNAポリメラーゼの構造解析2010
- Author(s)
  朴三用
- Organizer
  第47回日本蛋白質科学会
- Place of Presentation
  北海道大学(招待講演)
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] インフルエンザウイルスのRNAポリメラーゼサブユニットPA-PB1サブユニト間相互作用の解明2010
- Author(s)
  吉田尚史、尾林栄治、河合文啓、川口敦史、永田恭介、テイムジェレミー、朴三用
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] インフルエンザウイルスのRNAポリメラーゼサブユニットPA-PB1サブユニット間相互作用の解明2010
- Author(s)
  吉田尚史、尾林栄治、河合文啓、川口敦史、永田恭介、テイムジェレミー、朴三用
- Organizer
  第47回日本蛋白質科学会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] 新規抗インフルエンサウイルス薬の開発基盤となるRNAポリメラーゼの構造解析2010
- Author(s)
  朴三用
- Organizer
  第27回PFシンポジウム
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] インフルエンザウイルスのRNAポリメラーゼサブユニットPB1-PB2サブユニト間相互作用の解明2010
- Author(s)
  杉山佳奈子、尾林栄治、川口敦史、鈴木由佳理、テイムジェレミー、永田恭介、朴三用
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] 新規抗インフルエンザウイルス薬の開発基盤となるRNAポリメラーゼの構造解析2010
- Author(s)
  朴三用
- Organizer
  第34回阿蘇シンポジウム
- Place of Presentation
  阿蘇
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] インフルエンザウイルスのRNAポリメラーゼサブユニットPB1-2間相互作用の解明2010
- Author(s)
  杉山佳奈子、尾林栄治、川口敦史、鈴木由佳理、テイムジェレミー、永田恭介、朴三用
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22370044
[Presentation] インフルエンザウイルスのRNAポリメラーゼサブユニットPB1-PB2サブユニット間相互作用の解明2010
- Author(s)
  杉山佳奈子、尾林栄治、川口敦史、鈴木由佳理、テイムジェレミー、永田恭介、朴三用
- Organizer
  第47回日本蛋白質科学会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] 新規抗ウイルス薬の開発基盤となるRNAポリメラーゼの構造解析2010
- Author(s)
  朴三用
- Organizer
  平成22年度KASTフォーラム1ドイツバイオ交流フォーラム
- Place of Presentation
  川崎
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structural Insight into the Subunit Contact of the Influenza Virus RNA Polymerase2010
- Author(s)
  朴三用
- Organizer
  2^<nd> International Symposium on Drug Discovery and Design by NMR
- Place of Presentation
  Yokohama(招待講演)
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] 新規抗ウイルス薬の開発基盤となるRNAポリメラーゼの構造解析2010
- Author(s)
  朴三用
- Organizer
  大阪大学蛋白質研究所セミナー
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] 新規抗インフルエンザウイルス薬の開発基盤となるRNAポリメラーゼの構造解析2010
- Author(s)
  朴三用
- Organizer
  第34回阿蘇シンポジウム
- Place of Presentation
  阿蘇(招待講演)
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structural Insight into the Subunit Contact of the Influenza Virus RNA Polymerase2010
- Author(s)
  Sam-Yong Park
- Organizer
  2^<nd> International Symposium on Drug Discovery and Design by NMR
- Place of Presentation
  Yokohama City University
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] インフルエンザRNAポリメラーゼの構造解析2010
- Author(s)
  朴三用
- Organizer
  第47回日本蛋白質科学会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structural Insight in to the Subunit Contact of the Influenza Virus RNA Polymerase2009
- Author(s)
  Sam-Yong Park
- Organizer
  America Crystallographic Association
- Place of Presentation
  Toronto Canada
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structural Insight into the Subunit Contact of the Influenza Virus RNA Polymerase2009
- Author(s)
  Sam-Yong Park
- Organizer
  America Crystallographic Association
- Place of Presentation
  Toronto Canada
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structure and function of Root effect fish hemoglobin2009
- Author(s)
  S. Unzai, K. Imai, T. Yokoyama, SY Park, K. Nagai, J. Tame
- Organizer
  第47回日本生物物理学会
- Place of Presentation
  徳島文理大学
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structural Insight into the Subunit Contact of the Influenza Virus RNA Polymerase2009
- Author(s)
  Sam-Yong Park
- Organizer
  The 9th R. O. C-Japan Joint Seminar on Crystallography
- Place of Presentation
  Osaka University
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structural Insight into the Essential Subunit Contact of the Influenza Virus RNA Polymerase2009
- Author(s)
  E. Obayashi, K. Sugiyama, H. Yoshida, F. Kawai, A. Kawaguchi, Y. Suzuki, J. Tame, K. Nagata, SY Park
- Organizer
  第47回日本生物物理学会
- Place of Presentation
  徳島文理大学
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structural Insight into the Subunit Contact of the Influenza Virus RNA Polymerase2009
- Author(s)
  Sam-Yong Park
- Organizer
  9th KIAS-SUN Structure and Function
- Place of Presentation
  Seoul National University, Seoul, Korea
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Structural Insight in to the Essential PA-PB1 Subunit Contact of the Influenza Virus RNA Polymerase2009
- Author(s)
  Sam-Yong Park
- Organizer
  VII European Symposium of the Protein Society
- Place of Presentation
  Zurich, Switzerland
- Data Source
  KAKENHI-PROJECT-21370046
[Presentation] Studies of protein-protein and protein-RNA complexes by mass spectrometry, IUCr2008
- Author(s)
  Satoko Akashi, Masahiro Watanabe, Jonathan GHeddle, Satoru Unzai, Park SY, Jeremy R.H.Tame
- Organizer
  第21回国際結晶学連合会議
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] インフルエンザウイルスのRNAポリメラーゼにおけるサブユニット間相互作用2008
- Author(s)
  尾林栄治, 吉田尚史, 河合文啓,川口敦史, 永田恭介, Jeremy Tame,朴三用
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19370045
[Presentation] Haemoglobin as a drug target2008
- Author(s)
  Takeshi Yokoyama, Satoru Unzai, Park SY, Jeremy Tame
- Organizer
  The40th crystallographic meeting at Erice
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] Crystal structures of the clock protein EA4 from the silkworm bombyx mori2008
- Author(s)
  Park SY, T.Hiraki, N.Shibayama, S.Akashi
- Organizer
  The Joint 4th AOHUPO(Asian Oceania Human Proeome Organisation and 2nd PRICPS(Pacific Rim International Conference on Protein Science
- Place of Presentation
  Cairns, Australia
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] Haemoglobin as a drug target2008
- Author(s)
  Takeshi Yokoyama, Satoru Unzai, Sam-Yong Park, Jeremy
- Organizer
  The 40th crystallographic meeting at Erice
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-19370045
[Presentation] Crystal structure of the clock protein EA4 from the silkworm bombyx mori2008
- Author(s)
  Park SY, H. Hiraki, N. Shibayama, S. Akashi
- Organizer
  2^<nd> International conference on protein science
- Place of Presentation
  Cairns Ausrralia
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] Protonation states of buried histidine residues in human deoxyhemoglobin revealed by neutron crystallography2008
- Author(s)
  Sam-Yong Park, Toshiyuki Chatake, Naoya Shibayama, Yukiko Morimoto
- Organizer
  XVth International Conference on Oxygen Binding and Sensing Proteins
- Place of Presentation
  Aarhus, Denmark
- Data Source
  KAKENHI-PROJECT-19370045
[Presentation] Protonation states of buried histidine residues in human deoxyhemoglobin revealed by neutron crystallography2008
- Author(s)
  Park SY, Toshiyuki Chatake, Naoya Shibayama, Yukiko Morimoto
- Organizer
  XVth International Conference on Oxygen Binding and Sensing Proteins
- Place of Presentation
  Aarhus, Denmark
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] Dynamic allostery in the tryptophan-binding protein TRAP2007
- Author(s)
  Heddle JG, Akashi S, Park SY, Tame JR.
- Organizer
  Biophysics of ligand binding to drug tagets.
- Place of Presentation
  Strasbourg, France
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] X-ray Crystallography of Autotransporters from Pathogenic Bacteria2007
- Author(s)
  Kaoru Nishimura, Sam-Yong Park, Jeremy
- Organizer
  Molecular Microbiology Young Microbiologists Minisymposium Prokaryotic Membranes
- Place of Presentation
  Paris, France
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19370045
[Presentation] Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli2007
- Author(s)
  Park SY, JRH Tame
- Organizer
  Biophysics of ligand binding to drug targets. Workshop, llkirch, Strasbourg
- Place of Presentation
  France
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] X-ray Crystallography of Autotransporters from Pathogenic Bacteria.2007
- Author(s)
  Kaoru Nishimura, Sam-Yong Park, and Jeremy Tame
- Organizer
  Molecular Microbiology Young Microbiologists Minisymposium Prokaryotic Membranes.
- Place of Presentation
  Paris, France
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli2007
- Author(s)
  Park SY, JRH Tame
- Organizer
  24^<th> European Crystallographic Meeting
- Place of Presentation
  Marrakech, Morocco
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] Dynamic allostery in the tryptophan-binding protein TRAP2007
- Author(s)
  Heddle JG, Akashi S, Park SY, Tame JR.
- Organizer
  Biophysics of ligand binding to drug tagets.
- Place of Presentation
  Strasbourg, France
- Data Source
  KAKENHI-PROJECT-19370045
[Presentation] X-ray Crystallography of Autotransporters from Pathogenic Bacteria2007
- Author(s)
  Kaoru Nishimura, Sam-Yog Park, and Jeremy Tame
- Organizer
  Molecular Microbiology Young Microbiologists Minisymposium Prokaryotic Membranes
- Place of Presentation
  Paris,France
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-15083206
[Presentation] Dynamic allostery in the ring protein TRAP. Biophysics of ligand binding to drug targets. Workshop2007
- Author(s)
  Heddle JG, Akashi S, Park SY, Tame JR
- Organizer
  llkirch, Strasbourg
- Place of Presentation
  France
- Data Source
  KAKENHI-PROJECT-19570109
[Presentation] X-ray Crystallography of Autotransporters from Pathogenic Bacteria.2007
- Author(s)
  Kaoru Nishimura, Sam-Yong Park, and Jeremy Tame
- Organizer
  Molecular Microbiology Young Microbiologists Minisymposium Prokaryotic Membranes.
- Place of Presentation
  Paris, France
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19370045
[Presentation] リガンド結合状態および非結合状態のケナガマンモスヘモグロビンの結晶構造
- Author(s)
  Hiroki Noguchi, Satoru Unzai, Kevin L.Cambell, Chien Ho, Sam-Yong Park, and Jeremy R.H. Tame.
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-23570145
[Presentation] The structural basis for an essential subunit interaction in influenza virus RNA polymerase
- Author(s)
  1.Sam-Yong Park
- Organizer
  International School of Crystallography
- Place of Presentation
  Erice, Italty.
- Year and Date
  2014-05-30 – 2014-06-08
- Data Source
  KAKENHI-PROJECT-25291016
[Presentation] チシリン耐性黄色ブドウ球菌由来ペニシリン結合タンパク質３のX線結晶構造解析
- Author(s)
  吉田尚史、朴三用
- Organizer
  第14回日本蛋白質学会
- Place of Presentation
  横浜
- Year and Date
  2015-06-25 – 2015-06-27
- Data Source
  KAKENHI-PROJECT-25291016

1. UNZAI Satoru (60336592)

# of Collaborated Projects: 6 results

# of Collaborated Products: 25 results
2. TAME Jeremy R.H. (00336588)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. SHIRO Yoshitugu (70183051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIBAYAMA Naoya (20196439)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. TACHIWANA Hiroaki (70546382)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. KURUMIZAKA HITOSHI (80300870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. KAGAWA Wataru (70415123)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. KIMURA Hiroshi (30241392)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. SATO Mamoru (60170784)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. NAGATA Kyosuke (40180492)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. OSAKABE Akihisa

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
12. MIYA Yuta

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. MATSUMOTO Ryohei

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
14. ARIMURA Yasuhiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. HORIKOSHI Naoki

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. MAKINO Ryu (40101026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. FUKUNISHI Yoshihumi (60357895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SHIBATA Takehiko (70087550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MASUMOTO Hiroshi (70229384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. OHZEKI Jun-ichirou (30514088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Kawaguchi Atsushi (90532060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. Sugiyama Kanako (20623226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. Urano Takeshi (70293701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAKAMURA Hiro (80270594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Takeyasu Kunio (40135695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Takaori Akifumi (20324626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Arase Hisashi (10261900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. Iba Hideo (60111449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. Koyanagi Yoshio (80215417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 脇田隆字 (40280789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 藤田尚志 (10156870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 柳雄介 (40182365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 小池智 (30195630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 夏目徹 (00357683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 佐々木顕 (90211937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 小山隆太 (90431890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 梅名泰史 (10468267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 別所義隆 (70242815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 渡士幸一 (40378948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
40. SHIGA Tatsuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. KOMIYAMA Noboru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. Tsukuda Senko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. Iwamoto Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
44. Ohashi Hirofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. INOUE Asuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. TAME J.R.H.

# of Collaborated Projects: 0 results

# of Collaborated Products: 68 results
47. 鈴木信弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 高橋敏男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 生田達也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 明石知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
51. 木寺詔記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 大木規央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 鎌足雄司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Park Sam Yong 朴 三用

PARK Sam-yong 朴 三用

PAK Sam yong 朴 三用

Research Projects

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Co-Researchers

Structure and functional analysis of the SARS-CoV-2 Nucleocapsid ProteinPrincipal Investigator

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Structural analysis of various light-driven reaction mechanisms of light-sensitive proteins.Principal Investigator

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Molecular mechanism of photoactivation of a light-regulated adenylate cyclasePrincipal Investigator

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The mechanism analysis of influenza RNA polymerasePrincipal Investigator

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Structural basis for an essential subunit interaction in influenza virus RNA polymerase PB1-PB2Principal Investigator

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Park Sam Yong 朴三用

PARK Sam-yong 朴三用

PAK Sam yong 朴三用