Ikejima Kenichi 池嶋健一

… Alternative Names

IKEJIMA Kenichi 池嶋健一

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Researcher Number	20317382
Other IDs
External Links
Affiliation (Current)	2025: 順天堂大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2025: 順天堂大学, 医学部, 教授 2016: 順天堂大学, 医学部, 先任准教授 2011 – 2015: 順天堂大学, 医学(系)研究科(研究院), 准教授 2014: 順天堂大学, 医学研究科, 准教授 2014: 順天堂大学, 医学部, 准教授 … More 2013: 順天堂大学, 消化器内科, 准教授 2011 – 2012: 順天堂大学, 医学研究科, 准教授 2011: 順天堂大学, 医学(系)・研究科(研究院), 准教授 2007 – 2011: Juntendo University, Dept. of Gastroenterology, Associate Prof 2002 – 2006: Dept. of Gastroenterology, Juntendo Univ. School of Medicine, Assistant Professor, 医学部, 講師 2005: 医学部, 講師 1999 – 2001: 順天堂大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator 自然免疫 / メタボリックシンドローム / NKT細胞 / 非アルコール性脂肪肝炎（NASH) / 肝線維化 / レプチン / 腸内細菌叢 / 非アルコール性脂肪肝炎（NASH） / アミノ酸 / 免疫栄養 … More / 肝再生 / アディポネクチン / TNF-α / 肝星細胞 / Kupffer細胞 / 日本食 / サイトカインストーム / 腸肝相関 / COVID-19 / 代謝性障害性脂肪肝疾患（MAFLD） / 代謝障害性脂肪性肝疾患（MAFLD） / 細胞死 / エンドトキシン・ショック / リポポリサッカライド（LPS） / サイトカイン・ストーム / 代謝障害関連脂肪性肝疾患（MAFLD） / エンドトキシン / MASH / 非アルコール性脂肪性肝疾患（NAFLD） / MASLD / RIG-I / インスリン / 糖代謝 / 耐糖能異常 / 腸内マイクロバイオーム / hepatic fibrogenesis / interferon / chronic hepatitis C / nonalcoholic steatohepatitis (NASH) / adiponectin / leptin / adipocytokines / 肝類洞壁細胞 / アポトーシス / 抗ウイルス療法 / 低分子量ヘパリン / インターフェロン / アディポネクチンン / アディポサイトカイン / C型慢性肝炎 / NASH / 脂肪性肝疾患 / 肝発癌 / Th2サイトカイン / 非アルコール性脂肪肝炎 / 非アルコール性脂肪性肝疾患 / グリシン / 制御性T細胞 / チアゾリジン系誘導体 / アディポカイン / CD1d / NK細胞 / 非アルコール性脂肪肝炎(NASH) / PPAR-γ / STAT-3 / ピオグリタゾン / PPAR / 脂肪性肝炎 / 肝臓病学 / 肝類洞内皮細胞 / TGF-β / 細胞外基質 / 脂肪肝 / ICAM-1 / エンドトキシン肝障害 / 非アルコール性脂肪性肝炎 … More Except Principal Investigator オートファジー / 酸化ストレス / 肝線維化 / 肝再生 / PTEN / アルコール性肝障害 / エンドトキシン / ケモカイン / TNF-α / グリシン / 肝癌 / NASH / 脂肪性肝疾患 / リソソーム / インスリン抵抗性 / アポトーシス / 微小核 / 自然免疫 / 肝がん / リピドミクス / 脂肪毒性 / 非アルコール性脂肪肝炎 / 老化 / Toll-like receptor (TLR) / glycine / マクロファージ / 類洞内皮細胞 / 炎症性腸疾患 / アミノ酸 / 遊離脂肪酸 / 非アルコール脂肪肝炎 / 肝細胞癌 / 肝疾患 / バイオマーカー / 脂肪性肝炎 / 炎症 / 細胞死 / 肝障害 / TNFα / NAFLD / 薬物性肝障害 / 肝星細胞 / 免役チェックポイント阻害剤 / 代謝障害性脂肪性肝疾患 / 抗腫瘍免疫 / 不溶性核蛋白 / 核内構造体 / 核内脂肪滴 / 脂肪酸代謝 / 脂質合成 / 抗酸化物質 / 脂肪酸不飽和化酵素 / 筋肝連関 / 脂質 / ジェロントロジー / ジエントロジー / ユビキチン化 / 脂質代謝 / ヘパトカイン / サルコペニア / ジェントロジー / 膵炎 / 核マトリクス / 膵癌 / 核マトリクス蛋白 / リピドラフト / N-acetyleisteine / antioxidant / hepatic caricinogenesis / oxidative stress / steatohepatitis / N-アセチルシステイン / 抗酸化剤 / 肝発癌 / triplex DNA / gene delivery / sinusoidal endothelial cells / ステルス効果 / ヒアルロン酸グラフト化ポリLリジン櫛形共重合体 / 再生 / リホザイムライブラリ / ヒアルロン酸グラフト化ポリLリジン櫛型共重合体 / 3重鎖核酸法 / デコイ法 / 相分離性ナノ会合体 / 遺伝子デリバリ / ヒアルロン酸グラフト化ポリLリジン / ヒアルロン酸 / insulin resistance / hepatic stellate cells / TGF-β / adiponectin / leptin / adipokines / hepatic fibrogenesis / fatty liver / PPAR-γ / 炎症性サイトカイン / 肝類洞壁細胞 / メタボリックシンドローム / アディポネクチン / レプチン / liver / apoptosis / SMP 30 / 肝細胞 / SMP30 / macrophages / inflammatory bowel diseases / alcoholic liver disease / innate immunity / bacterial toxins / Toll-like receptor(Tlr) / LPS binding protein / Toll-like receotor(Tlr) / Toll-like receptor / CD14 / Kupffer細胞 / 炎病性腸疾患 / 腸内細菌 / chemokine / TNBS colitis / inflammatory bowel disease / Amino acids / 免疫薬理学的栄養作用 / 腸管 / TNBS腸炎 / 運動療法 / 食事療法 / 高脂肪食 / 脂肪肝 / カルニチン / 肝細胞がん / 小胞体ストレス / トランス脂肪酸 / 化学シャペロン / エピジェネティクス / 慢性肝炎 / カテプシン / 核膜蛋白 / 潰瘍性大腸炎 / ミトコンドリア / エイコサペンタエン酸 / 血管新生 / ROS / ネクローシス / アセトアミノフェン / CRP / 腸管透過性 / 肝マクロファージ / siRNAライブラリ / リボザイムライブラリ / inverse genomics Less

脂肪肝炎を基盤とする肝発癌過程におけるFGFファミリー分子の機能的関与Principal Investigator
- Principal Investigator
  
  池嶋健一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
Elucidation of the Pathophysiological Role of Micronucleus Induction and Stability in Liver Diseases
- Principal Investigator
  
  山科俊平
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
The role of nuclear proteins and structures mediated by autophagy dysfunction in the pathogenesis of the fatty liver disease.
- Principal Investigator
  
  渡辺純夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
Integrated multiomics analysis to investigate the mechanism of immunotherapy-resistant MAFLD-related hepatocarcinogenesis
- Principal Investigator
  
  今一義
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
Immunonutritional approach for innate immune dysregulation in metabolic dysfunction-associated fatty liver diseasePrincipal Investigator
- Principal Investigator
  
  Ikejima Kenichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
Mechanism of enhanced hepatotoxicity through fatty acid metabolic imbalance in the progression of fatty liver disease
- Principal Investigator
  
  Kon Kazuyoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
The impact of lipid composition alteration via beta-oxidation failure on the pathophysiological linkage between nonalcoholic steatohepatitis and sarcopenia
- Principal Investigator
  
  Kon Kazuyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Development of an early diagnosis method targeting nuclear matrix protein for autophagy-related digestive disorder disease
- Principal Investigator
  
  WATANABE SUMIO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Palmitic acid elicits insulin resistance and oxidative cell injury through clusterization of lipid rafts in murine hepatocytes.
- Principal Investigator
  
  Uchiyama Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Innate immune regulation in metabolic steatohepatitis and experimental therapeuticsPrincipal Investigator
- Principal Investigator
  
  Ikejima Kenichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
New therapeutic strategy to non-alcoholic liver disease targeting on autophagy
- Principal Investigator
  
  WATANEBE Sumio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
The new strategy of steatohepatitis targeting alteration of epigenetic regulation
- Principal Investigator
  
  KON Kazuyoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Innate immune regulation of hepatic metabolism and immuno-nutritional approach for nonalcoholic fatty liver diseasePrincipal Investigator
- Principal Investigator
  
  IKEJIMA Kenichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Novel biomarker for evaluation of autophagic dysfunction in the liver
- Principal Investigator
  
  YAMASHINA SHUNHEI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Central role of autophagy in the pathogenesis of gastrointestinal and hepatic diseases.
- Principal Investigator
  
  WATANABE Sumio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Role of innate immune system in the regulation of hepatic metabolism and pathogenesis of steatohepatitisPrincipal Investigator
- Principal Investigator
  
  IKEJIMA Kenichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Role of autophagy in liver diseases
- Principal Investigator
  
  YAMASHINA Shunhei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Pathogenesis and experimental therapeutics of metabolic syndrome-related liver diseasesPrincipal Investigator
- Principal Investigator
  
  IKEJIMA Kenichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Role of lipid and oxidative stress on carcinogenesis in the digestive system
- Principal Investigator
  
  WATANABE Sumio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
消化管・肝機能枢軸から見た薬物性肝障害機序の解明
- Principal Investigator
  
  鈴木聡子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Role of adipocytokine in progression and therapeutic resistance in chronic liver diseases and hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  IKEJIMA Kenichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Investigation of pathophysiology and therapeutic strategies for metabolic syndrome-related steatohepatitis
- Principal Investigator
  
  SATO Nobuhiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Genetic Manipulation of Sinusoidal Endothelial Cells
- Principal Investigator
  
  TAKEI Yoshiyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Inverse genomicsを用いた肝線維化に関わる遺伝子の網羅的探索
- Principal Investigator
  
  SATO Nobuhiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
肝臓におけるleptinの産生およびその病態生理的意義Principal Investigator
- Principal Investigator
  
  池嶋健一
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University
Innate immune response to gut-derived bacterial toxins in gastrointestinal andhepatic disorders
- Principal Investigator
  
  SATO Nobuhiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University School of Medicine
ROLE OF SENESCENCE MARKER PROTEIN-30 (SMP30) IN HEPATOCYTE APOPTOSIS
- Principal Investigator
  
  KITAMURA Tsuneo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JUNTENDO UNIVERSITY
Amino acids as immuno-moduratory nutrients: therapeutic approaches for gastrointestinal and hepatic disorders.
- Principal Investigator
  
  TAKEI Yoshiyuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Juntendo University

[Book] アルコールと医学生物学「非B非C肝癌におけるオートファジー関連蛋白発現の変化」2014
- Author(s)
  今一義、池嶋健一、渡辺純夫
- Total Pages
  4
- Publisher
  東洋書店
- Data Source
  KAKENHI-PROJECT-24590995
[Book] 消化器の臨床　「NAFLD/NASHの病態と適切な診療を知る　NAFLD/NASHの成因と病態」2014
- Author(s)
  森永真紀、今一義、池嶋健一、渡辺純夫
- Total Pages
  6
- Publisher
  ヴァンメディカル
- Data Source
  KAKENHI-PROJECT-24590995
[Book] 今日の治療指針　2013年版2013
- Author(s)
  池嶋健一
- Publisher
  アルコール性肝障害
- Data Source
  KAKENHI-PROJECT-24590996
[Book] アラキドン酸側鎖含有合成脂質8A8によるエンドトキシン肝障害の抑制効果.アルコールと医学生物学2010
- Author(s)
  池嶋健一, 朴南哲, 今一義, 青山友則, 山科俊平, 竹井謙之, 佐藤信紘, 渡辺純夫
- Publisher
  東洋書店
- Data Source
  KAKENHI-PROJECT-21590859
[Book] 第8章肝疾患10.脂肪肝,脂肪性肝炎.医学スーパーラーニングシリーズ消化器内科学2010
- Author(s)
  池嶋健一, 渡辺純夫
- Publisher
  シュプリンガー・ジャパン
- Data Source
  KAKENHI-PROJECT-21590859
[Book] 一般演題10トランス脂肪酸による肝細胞内脂肪貯留と酸化ストレス応答性の亢進第6回「酸化ストレスと肝」研究会記録酸化ストレスと肝疾患2010
- Author(s)
  今一義, 池嶋健一, 渡辺純夫
- Publisher
  メディカルトリビューン
- Data Source
  KAKENHI-PROJECT-21590859
[Book] 脂肪性肝炎における肝再生不全に対するpioglitazoneの改善効果.アルコールと医学生物学2009
- Author(s)
  青山友則, 池嶋健一, 今一義, 山形寿文, 山科俊平, 佐藤信紘, 渡辺純夫
- Publisher
  東洋書店
- Data Source
  KAKENHI-PROJECT-21590859
[Book] セッション5-肝疾患と酸化ストレス2-一般演題13. メタボリック症候群における肝再生不全 : pioglitazoneによる改善効果とそのメカニズム. 酸化ストレスと肝疾患第5巻谷川久一編2009
- Author(s)
  青山友則, 池嶋健一, 今一義, 奥村京子, 渡辺純夫
- Publisher
  メディカルトリビューン, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] セッション5-肝疾患と酸化ストレス2-一般演題13.メタボリック症候群における肝再生不全: pioglitazoneによる改善効果とそのメカニズム.酸化ストレスと肝疾患2009
- Author(s)
  青山友則, 池嶋健一, 今一義, 奥村京子, 渡辺純夫
- Publisher
  メディカルトリビューン
- Data Source
  KAKENHI-PROJECT-21590859
[Book] 脂肪性肝炎における肝再生不全に対するpioglitazoneの改善効果. アルコールと医学生物学Vol.28, アルコール医学生物学研究会編2009
- Author(s)
  青山友則, 池嶋健一, 今一義, 山形寿文, 山科俊平, 佐藤信紘, 渡辺純夫
- Publisher
  東洋書店, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] IV主要疾患の診断と治療B. 肝疾患8. 非アルコール性脂肪性肝疾患・脂肪性肝炎. 消化器内科レジデントハンドブック渡辺純夫, 北條麻理子編2008
- Author(s)
  池嶋健一
- Publisher
  中外医学社, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] II検査の実際11. 腹腔鏡, 肝生検. 消化器内科レジデントハンドブック渡辺純夫, 北條麻理子編2008
- Author(s)
  池嶋健一
- Publisher
  中外医学社, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] II章肝・胆・膵【1】肝臓I. NAFLDとNASH. 専門医のための薬物療法Q&A消化器渡辺純夫三輪洋人編2008
- Author(s)
  池嶋健一
- Publisher
  中外医学社, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] IV主要疾患の診断と治療B. 肝疾患1. 肝機能異常. 消化器内科レジデントハンドブック渡辺純夫, 北條麻理子編2008
- Author(s)
  池嶋健一
- Publisher
  中外医学社, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] 6. 治療2. 酸化ストレス. NASH診療best approach西原利治編2008
- Author(s)
  今一義, 池嶋健一, 渡辺純夫
- Publisher
  中外医学社, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] 女性・高齢者と飲酒アルコール医学・医療における性差. 別冊・医学のあゆみアルコール医学・医療の最前線竹井謙之編2008
- Author(s)
  池嶋健一
- Publisher
  医歯薬出版株式会社, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] 一般演題/411. 酸化ストレスに伴う肝細胞傷害における鉄イオンの細胞内動態と細胞死への影響. 酸化ストレスと肝疾患第4巻谷川久一編2008
- Author(s)
  内山明, 池嶋健一, 今一義, 渡辺純夫
- Publisher
  メディカル・ジャーナル社, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] アルコール性肝障害発症における代謝性素因の関与 : KK-Ayマウスを用いた検討. アルコールと医学生物学Vol.27, アルコール医学生物学研究会編2007
- Author(s)
  池嶋健一, 今一義, 奥村京子, 青山友則, 竹井謙之, 佐藤信紘, 渡辺純夫
- Publisher
  東洋書店, 東京
- Data Source
  KAKENHI-PROJECT-19590791
[Book] 研究報告/I. 病態メタボリックシンドロームにおける酸化ストレス刺激に伴う肝障害増悪の検討. 酸化ストレスと肝疾患第3巻アークメディア, 東京(谷川久一編)2007
- Author(s)
  今一義, 池嶋健一, 奥村京子, 青山友則, 渡辺純夫
- Data Source
  KAKENHI-PROJECT-19590791
[Book] Role of leptin in pathogenesis of NASH, In Frontiers in Hepatology.(Okita K, Ed.)2005
- Author(s)
  Ikejima K, Lang T, Yamashina S, Enomoto N, Takai Y, Sato N.
- Publisher
  Springer-Verlag, Tokyo
- Data Source
  KAKENHI-PROJECT-14657136
[Book] Genetic manipulation of liver sinusoidal endothelial cells. In Organ Microcirculation : A gateway to diagnostic and therapeutic interventions.2004
- Author(s)
  Takei Y, Ikejima K, Enomoto N, Maruyama A, Sato N.
- Publisher
  Springer-Verlag, Tokyo
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Benefit of an action camera in endoscopy education for medical students under COVID-192023
- Author(s)
  Uchiyama Akira、Yamashina Shunhei、Sato Toshifumi、Sakuma Satoshi、Tomiki Yuichi、Isayama Hiroyuki、Nagahara Akihito、Ikejima Kenichi
- Journal Title
  
  BMC Medical Education
  
  Volume: 23 Issue: 1 Pages: 693-693
- DOI
  10.1186/s12909-023-04702-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07922
[Journal Article] Endobronchial Watanabe Spigot Placement for Hepatic Abscess and Bronchobiliary Fistula Following Radiofrequency Ablation for Hepatocellular Carcinoma2023
- Author(s)
  Nishioki Toshihiko、Koyama Ryo、Okubo Hironao、Fukuo Yuka、Takasaki Yusuke、Yae Toshifumi、Banno Takamitsu、Kido Kenji、Takahashi Kazuhisa、Shiina Shuichiro、Ikejima Kenichi
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 7 Pages: 999-1004
- DOI
  10.2169/internalmedicine.0392-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07922
[Journal Article] MR Fingerprinting for Liver Tissue Characterization: A Histopathologic Correlation Study.2023
- Author(s)
  Fujita S, Sano K, Cruz G, Fukumura Y, Kawasaki H, Fukunaga I, Morita Y, Yoneyama M, Kamagata K, Abe O, Ikejima K, Botnar RM, Prieto C, Aoki S.
- Journal Title
  
  Radiology
  
  Volume: 306 Issue: 1 Pages: 150-159
- DOI
  10.1148/radiol.220736
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06912, KAKENHI-PROJECT-21K07922, KAKENHI-PROJECT-19K17244
[Journal Article] Hepatic steatosis and skeletal muscle alterations during the COVID‐19 lockdown in a cohort of patients with chronic liver disease in Japan2023
- Author(s)
  Uchiyama Akira、Kon Kazuyoshi、Sakuma Satoshi、Sato Toshifumi、Morinaga Maki、Fukada Hiroo、Yamagata Hisafumi、Yaginuma Reiko、Fukuhara Kyoko、Yamashina Shunhei、Nojiri Shuko、Ikejima Kenichi
- Journal Title
  
  Hepatology Research
  
  Volume: 54 Issue: 3 Pages: 272-283
- DOI
  10.1111/hepr.13981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07922
[Journal Article] Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis2023
- Author(s)
  Tsuchiya Y, Seki T, Kobayashi K, Komazawa-Sakon S, Shichino S, Nishina T, Fukuhara K, Ikejima K, Nagai H, Igarashi Y, Ueha S, Oikawa A, Tsurusaki S, Yamazaki S, Nishiyama C, Mikami T, Yagita H, Okumura K, Kido T, Miyajima A, Matsushima K, Imasaka M, Araki K, Imamura T, Ohmuraya M, Tanaka M, Nakano H
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 6304-6304
- DOI
  10.1038/s41467-023-42058-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K20666, KAKENHI-PROJECT-22K07007, KAKENHI-PROJECT-23K06489, KAKENHI-PROJECT-21K07922, KAKENHI-PLANNED-22H05064, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-23K21285, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K26860, KAKENHI-PROJECT-23K27398
[Journal Article] The Impact of Partial Splenic Embolization on Portal Hypertensive Gastropathy in Cirrhotic Patients with Portal Hypertension2023
- Author(s)
  Saeki Michio、Okubo Hironao、Takasaki Yusuke、Nakadera Eisuke、Fukuo Yuka、Fukada Hiroo、Hotchi Yuta、Maruyama Hitoshi、Kokubu Shigehiro、Shiina Shuichiro、Nagahara Akihito、Ikejima Kenichi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 7 Pages: 2662-2662
- DOI
  10.3390/jcm12072662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07922
[Journal Article] Gender-specific development of experimental autoimmune cholangitis induced by double-stranded RNA2022
- Author(s)
  Someya Shunin、Uchiyama Akira、Arai Kumiko、Kon Kazuyoshi、Yamashina Shunhei、Watanabe Sumio、Ikejima Kenichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 588 Pages: 90-96
- DOI
  10.1016/j.bbrc.2021.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07922
[Journal Article] Autophagic dysfunction in the liver enhances the expression of insoluble nuclear proteins 14-3-3ζ and importin α42022
- Author(s)
  Kousuke Izumi , Shunhei Yamashina , Tsutomu Fujimura, Sumio Watanabe , Kenichi Ikejima
- Journal Title
  
  Life Sci.
  
  Volume: 298 Pages: 120491-120491
- DOI
  10.1016/j.lfs.2022.120491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05880, KAKENHI-PROJECT-21K07922, KAKENHI-PROJECT-17K00874
[Journal Article] Carbohydrate-deficient transferrin is a sensitive marker of alcohol consumption in fatty liver disease2022
- Author(s)
  Morinaga Maki、Kon Kazuyoshi、Uchiyama Akira、Fukada Hiroo、Fukuhara Kyoko、Yaginuma Reiko、Nakadera Eisuke、Yamashina Shunhei、Ikejima Kenichi
- Journal Title
  
  Hepatology International
  
  Volume: 16 Issue: 2 Pages: 348-358
- DOI
  10.1007/s12072-022-10298-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07922
[Journal Article] Impact of Cabozantinib Exposure on Proteinuria and Muscle Toxicity in Patients with Unresectable Hepatocellular Carcinoma2022
- Author(s)
  Okubo Hironao、Ando Hitoshi、Takasaki Yusuke、Nakadera Eisuke、Fukuo Yuka、Shiina Shuichiro、Ikejima Kenichi
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 12 Pages: 1460-1460
- DOI
  10.3390/ph15121460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07922
[Journal Article] Gadoxetic acid-enhanced magnetic resonance imaging predicts hyperbilirubinemia induced by glecaprevir during hepatitis C virus treatment2022
- Author(s)
  Okubo Hironao、Atsukawa Masanori、Okubo Tomomi、Ando Hitoshi、Nakadera Eisuke、Ikejima Kenichi、Nagahara Akihito
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 7847-7847
- DOI
  10.1038/s41598-022-11707-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07922
[Journal Article] Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 20202021
- Author(s)
  Tokushige Katsutoshi、Ikejima Kenichi、Ono Masafumi、Eguchi Yuichiro、Kamada Yoshihiro、Itoh Yoshito、Akuta Norio、Yoneda Masato、Iwasa Motoh、Yoneda Masashi、Otsuka Motoyuki、Tamaki Nobuharu、Kogiso Tomomi、Miwa Hiroto、Chayama Kazuaki、Enomoto Nobuyuki、Shimosegawa Tooru、Takehara Tetsuo、Koike Kazuhiko
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 56 Issue: 11 Pages: 951-963
- DOI
  10.1007/s00535-021-01796-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08383, KAKENHI-PROJECT-21K07922, KAKENHI-PROJECT-21K08012
[Journal Article] Anti-CD321 antibody immunotherapy protects liver against ischemia and reperfusion-induced injury.2021
- Author(s)
  Enzhi Yin, Takeshi Fukuhara, Kazuyoshi Takeda, Yuko Kojima, Kyoko Fukuhara, Kenichi Ikejima, Hisashi Bashuda, Jiro Kitaura, Hideo Yagita, Ko Okumura, Koichiro Uchida
- Journal Title
  
  Scientific Reports
  
  Volume: 6322 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41598-021-85001-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07831, KAKENHI-PROJECT-20K17000, KAKENHI-PROJECT-18H02695, KAKENHI-PROJECT-20H03721, KAKENHI-PROJECT-21K07922
[Journal Article] Levocarnitine Supplementation Suppresses Lenvatinib-Related Sarcopenia in Hepatocellular Carcinoma Patients: Results of a Propensity Score Analysis2021
- Author(s)
  Okubo Hironao、Ando Hitoshi、Nakadera Eisuke、Ikejima Kenichi、Shiina Shuichiro、Nagahara Akihito
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 12 Pages: 4428-4428
- DOI
  10.3390/nu13124428
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07922
[Journal Article] Evidence‐based clinical?practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 20202021
- Author(s)
  Tokushige Katsutoshi、Ikejima Kenichi、Ono Masafumi、Eguchi Yuichiro、Kamada Yoshihiro、Itoh Yoshito、Akuta Norio、Yoneda Masato、Iwasa Motoh、Yoneda Masashi、Otsuka Motoyuki、Tamaki Nobuharu、Kogiso Tomomi、Miwa Hiroto、Chayama Kazuaki、Enomoto Nobuyuki、Shimosegawa Tooru、Takehara Tetsuo、Koike Kazuhiko
- Journal Title
  
  Hepatology Research
  
  Volume: 51 Issue: 10 Pages: 1013-1025
- DOI
  10.1111/hepr.13688
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08383, KAKENHI-PROJECT-21K07922, KAKENHI-PROJECT-21K08012
[Journal Article] Aging exacerbates high‐fat diet‐induced steatohepatitis through alteration in hepatic lipid metabolism in mice2020
- Author(s)
  Ishizuka Kei、Kon Kazuyoshi、Lee‐Okada Hyeon‐Cheol、Arai Kumiko、Uchiyama Akira、Yamashina Shunhei、Yokomizo Takehiko、Ikejima Kenichi
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: In press Issue: 8 Pages: 1437-1448
- DOI
  10.1111/jgh.15006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0199, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-17K09440, KAKENHI-PROJECT-20K17032
[Journal Article] Cathepsin L-deficiency enhances liver regeneration after partial hepatectomy2019
- Author(s)
  Sato Toshifumi、Yamashina Shunhei、Izumi Kosuke、Ueno Takashi、Koike Masato、Ikejima Kenichi、Peters Christoph、Watanabe Sumio
- Journal Title
  
  Life Sciences
  
  Volume: 221 Pages: 293-300
- DOI
  10.1016/j.lfs.2019.02.040
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-18K08016, KAKENHI-PROJECT-16H05293
[Journal Article] The Chemical Chaperone 4‐Phenylbutyric Acid Prevents Alcohol‐Induced Liver Injury in Obese KK‐A y Mice2019
- Author(s)
  Suzuki Maiko、Kon Kazuyoshi、Ikejima Kenichi、Arai Kumiko、Uchiyama Akira、Aoyama Tomonori、Yamashina Shunhei、Ueno Takashi、Watanabe Sumio
- Journal Title
  
  Alcoholism: Clinical and Experimental Research
  
  Volume: 43 Issue: 4 Pages: 617-27
- DOI
  10.1111/acer.13982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09440
[Journal Article] Rifaximin prevents ethanol-induced liver injury in obese KK-Ay mice through modulation of small intestinal microbiota signature2019
- Author(s)
  Kitagawa Ryuta、Kon Kazuyoshi、Uchiyama Akira、Arai Kumiko、Yamashina Shunhei、Kuwahara-Arai Kyoko、Kirikae Teruo、Ueno Takashi、Ikejima Kenichi
- Journal Title
  
  American Journal of Physiology-Gastrointestinal and Liver Physiology
  
  Volume: 317 Issue: 5 Pages: G707-G715
- DOI
  10.1152/ajpgi.00372.2018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09440
[Journal Article] Progress in research of NASH2018
- Author(s)
  渡辺純夫，今一義，池嶋健一
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 115 Issue: 1 Pages: 1-9
- DOI
  10.11405/nisshoshi.115.1
- NAID
  130006316870
- ISSN
  0446-6586, 1349-7693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09023
[Journal Article] Formation of p62-positive inclusion body is associated with macrophage polarization in non-alcoholic fatty liver disease.2018
- Author(s)
  Fukushima H, Yamashina S, Arakawa A, Taniguchi G, Aoyama T, Uchiyama A, Kon K, Ikejima K, Watanabe S.
- Journal Title
  
  Hepatol Res.
  
  Volume: 48 Issue: 9 Pages: 757-767
- DOI
  10.1111/hepr.13071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09023
[Journal Article] Formation of p62-positive inclusion body is associated with macrophage polarization in non-alcoholic fatty liver disease2018
- Author(s)
  Fukushima Hirofumi、Yamashina Shunhei、Arakawa Atsushi、Taniguchi Gentaro、Aoyama Tomonori、Uchiyama Akira、Kon Kazuyoshi、Ikejima Kenichi、Watanabe Sumio
- Journal Title
  
  Hepatology Research
  
  Volume: Feb 23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09022
[Journal Article] Spleen-derived lipocalin-2 in the portal vein regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice.2017
- Author(s)
  Aoyama T, Kuwahara-Arai K, Uchiyama A, Kon K, Okubo H, Yamashina S, Ikejima K, Kokubu S, Miyazaki A, Watanabe S.
- Journal Title
  
  Lab Invest.
  
  Volume: 97 Issue: 8 Pages: 890-902
- DOI
  10.1038/labinvest.2017.44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09023, KAKENHI-PROJECT-15K19350
[Journal Article] A Customized Online Nutrition Guidance System Is Effective for Treating Patients with Nonalcoholic Fatty Liver Disease by Supporting Continuity of Diet Therapy at Home: A Pilot Study2017
- Author(s)
  Aoyama T, Takada H, Uchiyama A, Kon K, Yamashina S, Ikejima K, Ban H, Watanabe S.
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 13 Pages: 1651-1656
- DOI
  10.2169/internalmedicine.56.8187
- NAID
  130006858091
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09023
[Journal Article] Sodium 4-phenylbutyric acid prevents murine acetaminophen hepatotoxicity by minimizing endoplasmic reticulum stress.2017
- Author(s)
  Kusama H, Kon K, Ikejima K, Arai K, Aoyama T, Uchiyama A, Yamashina S, Watanabe S.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 52 Issue: 5 Pages: 611-622
- DOI
  10.1007/s00535-016-1256-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09023
[Journal Article] A Customized Online Nutrition Guidance System Is Effective for Treating Patients with Nonalcoholic Fatty Liver Disease by Supporting Continuity of Diet Therapy at Home: A Pilot Study.2017
- Author(s)
  Supporting Continuity of Diet Therapy at Home: A Pilot Study. Aoyama T, Takada H, Uchiyama A, Kon K, Yamashina S, Ikejima K, Ban H, Watanabe S.
- Journal Title
  
  Intern Medcine
  
  Volume: 56(13) Pages: 1651-1656
- NAID
  130006858091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09022
[Journal Article] Inhibition of mTOR improves the impairment of acidification in autophagic vesicles caused by hepatic steatosis.2016
- Author(s)
  Nakadera E, Yamashina S, Izumi K, Inami Y, Sato T, Fukushima H, Kon K, Ikejima K, Ueno T, Watanabe S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 469(4) Issue: 4 Pages: 1104-10
- DOI
  10.1016/j.bbrc.2015.12.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09023
[Journal Article] Glycine prevents metabolic steatohepatitis in diabetic KK-Ay mice through modulation of hepatic innate immunity.2016
- Author(s)
  Takashima S, Ikejima K, Arai K, Yokokawa J, Kon K, Yamashina S, Watanabe S.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 311 Issue: 6 Pages: G1105-G1113
- DOI
  10.1152/ajpgi.00465.2015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09023
[Journal Article] L-carnitine prevents metabolic steatohepatitis in obese diabetic KK-Ay mice.2016
- Author(s)
  Kon K, Ikejima K, Morinaga M, Kusama H, Arai K, Aoyama T, Uchiyama A, Yamashina S, Watanabe S
- Journal Title
  
  Hepatology Research
  
  Volume: Apr Issue: 3 Pages: 44-54
- DOI
  10.1111/hepr.12720
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09022, KAKENHI-PROJECT-15K09023
[Journal Article] Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.2015
- Author(s)
  Watanabe S, Hashimoto E, Ikejima K, Uto H, Ono M, Sumida Y, Seike M,
- Journal Title
  
  J Gastroenterol
  
  Volume: 50(4) Issue: 4 Pages: 364-377
- DOI
  10.1007/s00535-015-1050-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590981, KAKENHI-PROJECT-24590996, KAKENHI-PROJECT-25460999, KAKENHI-PROJECT-26461010, KAKENHI-PROJECT-15K09009, KAKENHI-PROJECT-15K09010, KAKENHI-PROJECT-15K09023, KAKENHI-PROJECT-26461011
[Journal Article] Sodium 4-phenylbutyrate prevents murine dietary steatohepatitis caused by <i>trans</i>-fatty acid plus fructose2015
- Author(s)
  Morinaga M, Kon K, Saito H, Arai K, Kusama H, Uchiyama A, Yamashina S, Ikejima K, Watanabe S.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 57 Issue: 3 Pages: 183-191
- DOI
  10.3164/jcbn.15-75
- NAID
  130005106455
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09022, KAKENHI-PROJECT-15K09023
[Journal Article] Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.2015
- Author(s)
  Watanabe S, Hashimoto E, Ikejima K, Uto H, Ono M, Sumida Y, Seike M, Takei Y, Takehara T, Tokushige K, Nakajima A, Yoneda M, Saibara T, Shiota G, Sakaida I, Nakamuta M, Mizuta T, Tsubouchi H, Sugano K, Shimosegawa T.
- Journal Title
  
  Hepatol Res.
  
  Volume: 45 Issue: 4 Pages: 363-377
- DOI
  10.1111/hepr.12511
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590996, KAKENHI-PROJECT-15K09009, KAKENHI-PROJECT-26461010, KAKENHI-PROJECT-26461011, KAKENHI-PROJECT-25460999
[Journal Article] NAFLDの診療・研究の進歩．2014
- Author(s)
  池嶋健一，渡辺純夫．
- Journal Title
  
  日本消化器病学会雑誌
  
  Volume: 111 Pages: 4-13
- NAID
  130003383342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590996
[Journal Article] 特集・NAFLD/NASHと肝発癌－その実態と適切な診療に迫る－［NAFLD/NASHの病態と適切な診療を知る］NAFLD/NASHの成因と病態．2014
- Author(s)
  森永真紀，今一義，池嶋健一，渡辺純夫．
- Journal Title
  
  消化器の臨床
  
  Volume: 17 Pages: 19-24
- Data Source
  KAKENHI-PROJECT-24590996
[Journal Article] Abnormality of autophagic function and cathepsin expression in the liver from patients with non-alcoholic fatty liver disease.2014
- Author(s)
  Yuka Fukuo, Shunhei Yamashina, Hiroshi Sonoue, Atsushi Arakawa, Eisuke Nakadera, Tomonori Aoyama, Akira Uchiyama, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
- Journal Title
  
  Hepatology Research
  
  Volume: 未定 Issue: 9 Pages: 1026-1036
- DOI
  10.1111/hepr.12282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590989, KAKENHI-PROJECT-24390191, KAKENHI-PROJECT-24590995, KAKENHI-PROJECT-24590996
[Journal Article] 特集：生活習慣病とNKT細胞－病態モジュレーターの面から　非アルコール性脂肪肝炎の病態形成におけるNKT細胞の関与．2013
- Author(s)
  池嶋健一，渡辺純夫．
- Journal Title
  
  医学のあゆみ
  
  Volume: 246 Pages: 235-240
- Data Source
  KAKENHI-PROJECT-24590996
[Journal Article] Innate immune responses involving natural killer and natural killer T cells promote liver regeneration after partial hepatectomy in mice.2013
- Author(s)
  Hosoya S.Ikejima K.Takeda K.Arai K.Ishikawa S.Yamagata H.Aoyama T.Kon K.Yamashina S.Kon K.Watanabe S.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 304 Issue: 3 Pages: G293-G299
- DOI
  10.1152/ajpgi.00083.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590995, KAKENHI-PROJECT-24590996
[Journal Article] 特集：NASH－病態と治療，8．NAFLD/NASHの治療(3)　脂質代謝改善薬による治療．2013
- Author(s)
  池嶋健一
- Journal Title
  
  臨床消化器内科
  
  Volume: 28 Pages: 487-493
- Data Source
  KAKENHI-PROJECT-24590996
[Journal Article] Altered expression and function of hepatic natural killer T cells in obese and diabetic KK-A(y) mice.2012
- Author(s)
  Yamagata H
- Journal Title
  
  Hepatol Res
  
  Volume: 43 Issue: 3 Pages: 276-88
- DOI
  10.1111/j.1872-034x.2012.01062.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-24590995, KAKENHI-PROJECT-24590996
[Journal Article] Supression of autophagy sensitizes Kupffer cells to endotoxin.2012
- Author(s)
  Fukada H, Yamashina S, Izumi K, Komatsu M, Tanaka K, Ikejima K, Watanabe S.
- Journal Title
  
  Hepatol. Res.
  
  Volume: 42 Issue: 11 Pages: 1112-1118
- DOI
  10.1111/j.1872-034x.2012.01024.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590996
[Journal Article] Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling2012
- Author(s)
  Imajo K, Fujita K, Yoneda M, Nozaki Y, Ogawa Y, Shinohara Y, Kato S, Mawatari H, Shibata W, Kitani H, Ikejima K, Kirikoshi H, Nakajima N, Saito S, Maeyama S, Watanabe S, Wada K, Nakajima A
- Journal Title
  
  Cell Metab
  
  Volume: 16(1) Issue: 1 Pages: 44-54
- DOI
  10.1016/j.cmet.2012.05.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659402, KAKENHI-PROJECT-24590996, KAKENHI-PROJECT-24659823
[Journal Article] Loss of autophagy promotes murine acetaminophen hepatotoxicity2011
- Author(s)
  Igusa Y, Yamashina S, et al
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 47 Issue: 4 Pages: 433-443
- DOI
  10.1007/s00535-011-0500-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390234, KAKENHI-PROJECT-24590996
[Journal Article] Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells2011
- Author(s)
  Wang X, Ikejima K, Kon K, Arai K, Aoyama T, Okumura K, Abe W, Sato N, Watanabe S
- Journal Title
  
  J Hepatol
  
  Volume: 55(2) Pages: 379-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Loss of autophagy promotes murine acetaminophen hepatotoxicity2011
- Author(s)
  Igusa Y, Yamashina S, Izumi K, Inami Y, Fukada H, Komatsu M, Tanaka K, Ikejima K
- Journal Title
  
  Watanabe S J Gastroenterol
- NAID
  10030650144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390234
[Journal Article] 特集II NASH/NAFLD発症のメカニズム肝NKT細胞による脂肪性肝炎発症制御メカニズム2011
- Author(s)
  池嶋健一, 山形寿文, 石川幸子, 細谷聡子, 今一義, 渡辺純夫
- Journal Title
  
  消化器内科
  
  Volume: 52(5) Pages: 543-547
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression2011
- Author(s)
  Inami Y, Yamashina S, Izumi K, Ueno T, Tanida I, Ikejima K, Watanabe S
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412(4) Pages: 618-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390234
[Journal Article] Hepatic steatosis inhibits autophagic proteolysis via impairment aut ophagosomal acidification and cathepsin expression2011
- Author(s)
  Inami Y, Yamashina S, Izumi K, Ueno T Tanida I, Ikejima K, Watanabe S
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Pages: 618-625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Izunai K, Ueno T Tanida I, Watanabe S.Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression2011
- Author(s)
  Inami Y, Yamashina S, Ikejima K, et al.(7人中6番目)
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Pages: 618-625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice2011
- Author(s)
  Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
- Journal Title
  
  J Hepatol
  
  Volume: 54(6) Pages: 1195-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集全身疾患としての非アルコール性脂肪性肝疾患(NAFLD) NAFLD/NASHの病態2011
- Author(s)
  池嶋健一, 渡辺純夫
- Journal Title
  
  診断と治療
  
  Volume: 99(9) Pages: 1498-1506
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Loss of autophagy promotes murine ace taminophen hepatotoxicity2011
- Author(s)
  Igusa Y, Yamashina S, Izumi K, Inami Y, Fukada H, Komatsu M, Tanaka K, Ikejima K, Watanabe S
- Journal Title
  
  J Gastroenterol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article]2010
- Author(s)
  池嶋健一, 渡辺純夫
- Journal Title
  
  第8章肝疾患 10. 脂肪肝, 脂肪性肝炎. 医学スーパーラーニングシリーズ消化器内科学(渡辺純夫編)(シュプリンガー・ジャパン)
  
  Pages: 254-258
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集「NASHの診断と治療」NAFLD・NASHの治療アプローチ-理論的背景とエビデンス-2010
- Author(s)
  池嶋健一
- Journal Title
  
  診療と新薬
  
  Volume: 47(2) Pages: 37-45
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Diabetic KK-Ay mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen2010
- Author(s)
  Kon K, Ikejima K, Okumura K, Arai K, Aoyama T, Watanabe S
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy.2010
- Author(s)
  Mizui T, Yamashina S, Ikejima K, et al., (12人中7番目)
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 195-203
- NAID
  10027214573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集非アルコール性脂肪肝炎(NASH)-病態の解明と診断・治療法の確立NASH/NAFLDの治療法インスリン抵抗性改善薬2010
- Author(s)
  今一義, 池嶋健一, 渡辺純夫
- Journal Title
  
  Current Therapy
  
  Volume: 28(12) Pages: 37-42
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Diabetic KK-A^y mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen.2010
- Author(s)
  Kon K, Ikejima K, Okumura K, et al., (6人中2番目)
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集肝胆膵薬物治療学の進歩-この30年-肝臓分野: VII. NASH・AIH・PBCベザフィブラート2010
- Author(s)
  池嶋健一
- Journal Title
  
  肝胆膵
  
  Volume: 61(6) Pages: 1107-1111
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy2010
- Author(s)
  Mizui T, Yamashina S, Tanida I, Takei Y, Ueno T, Sakamoto N, Ikejima K, Kitamura T, Enomoto N, Sakai T, Kominami E, Watanabe S
- Journal Title
  
  J Gastroenterol
  
  Volume: 45(2) Pages: 195-203
- NAID
  10027214573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集NASH II.基礎的メカニズムの解明1. NASHモデル2010
- Author(s)
  池嶋健一, 宮地隆史, 渡辺純夫
- Journal Title
  
  The Lipid
  
  Volume: 21(3) Pages: 38-45
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 臨時増刊NASH/NAFLDのすべて成因から栄養療法までNASH/NAFLDと関連疾患Topics線維化の成立機構と診断法2010
- Author(s)
  池嶋健一, 福原京子, 渡辺純夫
- Journal Title
  
  臨床栄養
  
  Volume: 116(6) Pages: 665-670
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集 NASH II.基礎的メカニズムの解明1.NASHモデル2010
- Author(s)
  池嶋健一, 宮地隆史, 渡辺純夫
- Journal Title
  
  The Lipid
  
  Volume: 21 Pages: 38-45
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] III.消化器疾患7.肝硬変・肝不全.テーラーメイド治療のための治療薬の選択と使用法ガイドライン実地医家に必須の56疾患2010
- Author(s)
  池嶋健一
- Journal Title
  
  Medical Practice
  
  Volume: vol.27(臨時増刊号) Pages: 136-142
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Hepatic sinusoidal cells in health and disease : update from the 14th International Symposium2009
- Author(s)
  Smedsrod B, Le Couteur D, Ikejima K, Jaeschke H, Kawada N, Naito M, Knolle P, Nagy L, Senoo H, Vidal-Vanaclocha F, Yamaguchi N
- Journal Title
  
  Liver Int
  
  Volume: 29(4) Pages: 490-501
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集NASH NASHの治療22009
- Author(s)
  池嶋健一, 渡辺純夫
- Journal Title
  
  薬物療法.治療学
  
  Volume: 43(10) Pages: 69-74
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice2009
- Author(s)
  Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Watanabe S
- Journal Title
  
  Hepatology
  
  Volume: 49(5) Pages: 1636-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] A Special Edition 4 NAFLD/NASHの発症機序2009
- Author(s)
  今一義, 池嶋健一, 渡辺純夫
- Journal Title
  
  BIO Clinica
  
  Volume: 24(13) Pages: 30-34
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集肝病態生理研究のあゆみ16.肝星細胞活性化に対するPTENの抑制効果2009
- Author(s)
  高島基樹, 池嶋健一, 今一義, 山科俊平, 鈴木聡子, 渡辺純夫
- Journal Title
  
  薬理と治療(JPT)
  
  Volume: 37
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Role of mitochondria in liver pathophysiology2009
- Author(s)
  Yamashina S, Sato N, Kon K, Ikejima K, Watanabe S
- Journal Title
  
  Drug Discovery Today : Disease Mechanisms
  
  Volume: 6(1-4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-A^y mice2009
- Author(s)
  Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Watanabe S.
- Journal Title
  
  Hepatology. 49(5)
  
  Pages: 1636-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation2009
- Author(s)
  Takashima M, Parsons CJ, Ikejima K, Watanabe S, White ES, Rippe RA
- Journal Title
  
  J. Gastroenterol
  
  Volume: 44(8) Pages: 847-55
- NAID
  10025176656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Synthetic triglyceride containing an arachidonic acid branch(8A8) prevents lipopolysaccharide-induced liver injury2009
- Author(s)
  Piao N, Ikejima K, Kon K, Aoyama T, Osada T, Takei Y, Sato N, Watanabe S
- Journal Title
  
  Life Sci
  
  Volume: 85(17-18) Pages: 617-24
- NAID
  110007125463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation2009
- Author(s)
  Takashima M, Parsons CJ, Ikejima K, Watanabe S, White ES, Rippe RA
- Journal Title
  
  J.Gastroenterol. 44(8)
  
  Pages: 847-55
- NAID
  10025176656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集肝疾患を生活習慣から考えるII.非アルコール性脂肪性肝障害の最近の動向2) NASH(1)病因、病態の新しい展開2009
- Author(s)
  柳沼礼子, 池嶋健一, 渡辺純夫
- Journal Title
  
  成人病と生活習慣病
  
  Volume: 39(4)
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] 特集肝病態生理研究のあゆみ17.肝細胞内脂肪的蓄積と肝細胞しにおける肝細胞内貯蔵鉄の役割2009
- Author(s)
  今一義, 池嶋健一, 青山友則, 山形寿文, 渡辺純夫
- Journal Title
  
  薬理と治療(JPT)
  
  Volume: 3
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice2009
- Author(s)
  Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Watanabe S
- Journal Title
  
  Hepatology 49(5)
  
  Pages: 1636-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Synthetic triglyceride containing an arachidonic acid branch(8A8)prevents lipopolysaccharide-induced liver injury2009
- Author(s)
  Piao N, Ikejima K, Kon K, Aoyama T, Osada T, Takei Y, Sato N, Watanabe S.
- Journal Title
  
  Life Sci. 85(17-18)
  
  Pages: 617-24
- NAID
  110007125463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590859
[Journal Article] Death receptor 5 mediatedapoptosis contributes to cholestatic liver disease2008
- Author(s)
  Takeda K, Kojima Y, Ikejima K, Harada K, Yamashina S, Okumura K, Aoyama T, Frese S, Ikeda H, Haynes N, Cretney E, Yagita H, Sueyoshi N, SatoN, Nakanuma Y, Smyth M, Okumura K
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 105(31)
  
  Pages: 10895-10900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集ウイルス性慢性肝炎 : 診断と治療の進歩トピックスIV. C型慢性肝炎の抗ウイルス療法2. C型慢性肝炎の進展と治療抵抗性2)宿主側因子の関与2008
- Author(s)
  池嶋健一, 柳沼礼子, 渡辺純夫
- Journal Title
  
  日本内科学会雑誌 97(1)
  
  Pages: 69-74
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集肝疾患と糖代謝, 脂質代謝VI. 糖代謝および脂質代謝異常と肝臓4. 脂肪肝と肝切除2008
- Author(s)
  池嶋健一, 青山友則, 渡辺純夫
- Journal Title
  
  肝胆膵 56(1)
  
  Pages: 119-125
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 連載第18回No.35シグナル伝達を理解するために必要な知識Eカドヘリンによるシグナル伝達2008
- Author(s)
  高島基樹, 池嶋健一, 渡辺純夫
- Journal Title
  
  分子消化器病 5(2)
  
  Pages: 68-71
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] KK-Ayマウスにおける肝再生不全-Pioglitazoneによる改善効果の検討-.2008
- Author(s)
  青山友則, 池嶋健一, 今一義, 山形寿文, 柳沼礼子, 山科俊平, 渡辺純夫.
- Journal Title
  
  薬理と治療(JPT) 36suppl
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集II鉄代謝と消化器疾患酸化ストレスに伴う肝細胞障害における鉄イオンの細胞内動態と細胞死への影響2008
- Author(s)
  内山明, 池嶋健一, 今一義, 渡辺純夫
- Journal Title
  
  消化器科 46(2)
  
  Pages: 229-233
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集C型肝炎のすべて2009合併症を有する患者のHCV治療肝脂肪化合併HCVとInterferon治療2008
- Author(s)
  柳沼礼子, 池嶋健一, 渡辺純夫
- Journal Title
  
  肝胆膵 57(5)
  
  Pages: 949-957
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 1. ペグインターフェロン・リバビリン併用療法の治療成績2008
- Author(s)
  渡辺純夫, 鈴木聡子, 池嶋健一
- Journal Title
  
  Progress in Medicine 28(11)
  
  Pages: 2625-2629
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Liver diseases and metabolic syndrome2008
- Author(s)
  Watanabe S, Yaginuma R, Ikejima K, Miyazaki A
- Journal Title
  
  J. Gastroenterol 43
  
  Pages: 509-518
- NAID
  10021937059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集NASH/NAFLDの臨床および研究の進歩NASH/NAFLDの成因と病態2008
- Author(s)
  今一義, 池嶋健一, 渡辺純夫
- Journal Title
  
  Medical Science Digest 36(7)
  
  Pages: 27-30
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集肝病態生理研究のあゆみ12. 酸化ストレスに伴う肝細胞障害における鉄イオンの細胞内動態と細胞死への影響2008
- Author(s)
  内山明, 池嶋健一, 今一義, 渡辺純夫
- Journal Title
  
  薬理と治療(JPT) 36suppl
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 第42回日本成人病(生活習慣病)学会 : 「教育講演」より脂肪肝から肝癌へ-NASHの病態を考える2008
- Author(s)
  柳沼礼子, 池嶋健一, 渡辺純夫
- Journal Title
  
  成人病と生活習慣病 38(5)
  
  Pages: 539-545
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集肝病態生理研究のあゆみ11. Sphingosine1-phosphate(S1P)の肝類洞内皮細胞に及ぼす影響2008
- Author(s)
  北村庸雄, 鄭冬梅, 池嶋健一, 榎本信行, 山科俊平, 今一義, 鈴木聡子, 竹井謙之, 佐藤信紘, 渡辺純夫
- Journal Title
  
  薬理と治療(JPT) 36suppl
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集肝病態生理研究のあゆみ19. KK-Ayマウスにおける肝再生不全-Pioglitazoneによる改善効果の検討-2008
- Author(s)
  青山友則, 池嶋健一, 今一義, 山形寿文, 柳沼礼子, 山科俊平, 渡辺純夫
- Journal Title
  
  薬理と治療(JPT) 36suppl
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集肝病態生理研究のあゆみ27. NAFLD患者に対する低用量ピオグリタゾン投与の有用性について2008
- Author(s)
  柳沼礼子, 池嶋健一, 福原京子, 青山友則, 今一義, 水井智和, 山科俊平, 鈴木聡子, 渡辺純夫
- Journal Title
  
  薬理と治療(JPT) 36suppl
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Translocation of Iron from Lysosomes into Mitochondria is a Key Event During Oxidative Stress-Induced Hepatocellular Injury2008
- Author(s)
  Uchiyama A, Kim JS, Kon K, Jaeschke H, Ikejima K, Watanabe S, Lemasters JJ
- Journal Title
  
  Hepatology 48(5)
  
  Pages: 1644-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Low molecular weight heparin prevents hepatic fibrogenesis caused carbon tetrachloride in the rat.2007
- Author(s)
  Abe W, Ikejima K, Lang T, Okumura K, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  J. Hepatol. 46
  
  Pages: 286-294
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] 特集 : NASH-最新の知見4. NASHの成因と病態(2)NASHとメタボリックシンドローム2007
- Author(s)
  池嶋健一, 今一義, 青山友則, 山科俊平, 鈴木聡子, 渡辺純夫
- Journal Title
  
  臨床消化器内科 22(11)
  
  Pages: 1451-1458
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] メタボリックシンドロームにおける薬物性肝障害の増悪-KKAyマウスを用いた検討-2007
- Author(s)
  今一義, 池嶋健一, 青山友則, 竹井謙之, 渡辺純夫
- Journal Title
  
  薬理と治療 35suppl
  
  Pages: 253-256
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Role of adipocytokines in hepatic fibrogenesis2007
- Author(s)
  Ikejima K, Okumura K, Kon K, Takei Y, Sato N.
- Journal Title
  
  J.Gastroenterol.Hepatol 22
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity2007
- Author(s)
  Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N
- Journal Title
  
  J. Gastroenterol. Hepatol 22(3)
  
  Pages: 423-428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Role of adipocytokines in hepatic fibrogenesis.2007
- Author(s)
  Ikejima K, Okumura K, Kon K. Takei Y, Sato N.
- Journal Title
  
  J. Gastroen terol. Hepatol. 22(Suppll)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] 特集プライマリ・ケア医のためのNAFLDの診かた-非アルコール性脂肪性肝疾患への対応と最新知見-2007
- Author(s)
  池嶋健一, 今一義, 渡辺純夫
- Journal Title
  
  各論 : NAFLDの治療高血圧合併例. 治療 89
  
  Pages: 1691-1695
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Low molecular weight heparin prevents hepatic fibrogenesis caused by carbon tetrachloride in the rat.2007
- Author(s)
  Abe W, Ikejima K, Lang T, Okumura K, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  J.Hepatol. 46
  
  Pages: 286-294
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Role of adipocytokines in hepatic fibrogenesis2007
- Author(s)
  Ikejima K, Okumura K, Kon K, Takei Y, Sato N
- Journal Title
  
  J. Gastroenterol. Hepatol 22(Suppl1)
  
  Pages: 87-92
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity2007
- Author(s)
  Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
- Journal Title
  
  J.Gastroenterol.Hepatol. 22(3)
  
  Pages: 423-428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] 特集子供を蝕む大人の病気各論脂肪肝/NASH/アルコール性肝障害2007
- Author(s)
  今一義, 池嶋健一, 渡辺純夫
- Journal Title
  
  小児科 48(5)
  
  Pages: 563-568
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Orthotopic hepatocellular carcinoma model with a com rolle and reproducible tumorigenicity.2007
- Author(s)
  Oktubo H, Takei Y. Serizawa N, Enomoto N. Ikejima K. Sato N.
- Journal Title
  
  J. Gastroenterol. Hepatol. 22(3)
  
  Pages: 423-428
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity2007
- Author(s)
  Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
- Journal Title
  
  J.Gastroenterol.Hepatol 22(3)
  
  Pages: 423-428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity.2007
- Author(s)
  Okubo H. Takei Y. Serizawa N. Enomoto N. Ikejima K. Sato N.
- Journal Title
  
  J. Gastroenterol. Hepatol 22(3)
  
  Pages: 423-428
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390213
[Journal Article] Role of apoptosis in acetaminophen hepatotoxicity2007
- Author(s)
  Kon K, Ikejima K, Okumura K, Aoyama T, Arai K, Takei Y, Lemasters JJ, Sato N
- Journal Title
  
  J. Gastroenterol. Hepatol 22(Suppl1)
  
  Pages: 49-52
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] 特集非アルコール性脂肪性肝炎(NASH) -疾患概念からマネージメントまで- 肝発癌発癌機序.2006
- Author(s)
  池嶋健一, 青山友則.
- Journal Title
  
  肝胆膵 53(3)
  
  Pages: 401-408
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Orthotopic Hepatocellular Carcinoma Model with a Controlled and Reproducible Tumorigenicity.2006
- Author(s)
  Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
- Journal Title
  
  Journal of Gastroenterology and Hepatology (in press)
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] 非アルコール性脂肪性肝炎におけるレプチンの役割.2006
- Author(s)
  池嶋健一, 佐藤信紘.
- Journal Title
  
  最新医学 61(5)
  
  Pages: 1033-1039
- NAID
  40007262381
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Genetic Manipulation of Sinusoidal Endothelial Cells2006
- Author(s)
  Yoshiyuki Takei, Atsushi Maruyama, Kenichi Ikejima, et al.
- Journal Title
  
  Journal of Gastroenterology and Hepatology (in press)
- NAID
  110004011831
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] 特集非B非C型肝炎 4.NASHと非B非C型肝炎 (2)NASHにおける病態進展の危険因子.2006
- Author(s)
  池嶋健一, 奥村京子, 今一義, 青山友則, 竹井謙之, 佐藤信紘.
- Journal Title
  
  臨床消火器内科 21(12)
  
  Pages: 1621-1628
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] 特集生活習慣と肝臓病:診断と治療の進歩トピックスV.肥満をめぐる進歩 2.レブチンの概念2006
- Author(s)
  池嶋健一, 佐藤信紘.
- Journal Title
  
  日本内科学会雑誌 95(1)
  
  Pages: 94-99
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] 特集生活習慣と肝臓病:診断と治療の進歩トピックスV.肥満をめぐる進歩 2.レプチンの概念2006
- Author(s)
  池嶋健一, 佐藤信紘
- Journal Title
  
  日本内科学会雑誌 95(1)
  
  Pages: 94-99
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Hepatic steatosis is a predictor of poor response to interferon α-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C.2006
- Author(s)
  Yaginuma R, Ikejima K, Okumura K, Kon K, Suzuki S, Takei Y, Sato N.
- Journal Title
  
  Hepatol Res. 35(1)
  
  Pages: 19-25
- NAID
  10020329566
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK・A^y mice.2006
- Author(s)
  Okumura K, Ikejima K, Kon K, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol. Res. 36
  
  Pages: 217-228
- NAID
  10018640284
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK-Ay mice.2006
- Author(s)
  Okumura K, Ikejima K, Kon K, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol.Res. 36
  
  Pages: 217-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis : role of intracellular calcium and nitric oxide.2006
- Author(s)
  Zheng DM, Kitamura T, Ikejima K, Enomoto N, Yamashina S, Suzuki S, Takei Y, Sato N.
- Journal Title
  
  Hepatology 44
  
  Pages: 1278-1287
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Protective effect of pioglitazone against endotoxin-induced liver injury through prevention of Kupffer cell sensitization.2005
- Author(s)
  Enomoto N, Takei Y, Yamashina S, Ikejima K, Kitamura T, Sato N.
- Journal Title
  
  Alcohol Clin.Exp.Res. 29(12 Suppl)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Roles of Kupffer cells in alcoholic liver disease.2005
- Author(s)
  Takei Y, Enomoto N, Ikejima K, Yamashina S, Kitamura T, Sato N
- Journal Title
  
  In Comprehensive Handbook of Alcohol Related Pathology (Academic Press, London) (Preedy VR and Watson RR, Eds)
  
  Pages: 749-759
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] The role of leptin in progression of non-alcoholic fatty liver disease.2005
- Author(s)
  Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol.Res. 33(2)
  
  Pages: 151-154
- NAID
  10016809329
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Hepatic steatosis is a predictor of poor response to interferon α-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C.2005
- Author(s)
  Yaginuma R, Ikejima K, Okumura K, Kon K, Suzuki S, Takei Y, Sato N.
- Journal Title
  
  Hepatol.Res.
- NAID
  10020329566
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Smad and p38 MAPK signaling pathways independently regulate α1(I) collagen gene expression in unstimulated and TGF-β stimulated hepatic stellate cells.2005
- Author(s)
  Tsukada S, Westwick JK, Ikejima K, Sato N, Rippe RA.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 10055-10064
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] NASHの発症・進展におけるレプチンの関与.2005
- Author(s)
  池嶋健一, 佐藤信紘.
- Journal Title
  
  消化器科 40
  
  Pages: 79-83
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] The role of leptin in progression of non-alcoholic fatty liver disease.2005
- Author(s)
  Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol Res. 33
  
  Pages: 151-154
- NAID
  10016809329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] メタボリックシンドロームと肝臓-特にレプチンの役割.2005
- Author(s)
  池嶋健一, 佐藤信紘
- Journal Title
  
  日本消化器病学会雑誌 102(11)
  
  Pages: 1392-1397
- NAID
  10016947860
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] メタボリックシンドロームと肝臓-特にレプチンの役割.2005
- Author(s)
  池嶋健一, 佐藤信紘.
- Journal Title
  
  日本消化器病学会雑誌 102(11)
  
  Pages: 1392-1397
- NAID
  10016947860
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Glycine as a therapeutic immuno-nutrient for alcoholic liver disease.2005
- Author(s)
  Yamashina S, Ikejima K, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Alcohol Clin Exp Res. 29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Ethanol-induced sensitization to endotoxin in Kupffer cells is dependent upon oxidative stress.2005
- Author(s)
  Yamashina S, Takei Y, Ikejima K, Enomoto N, Kitamura T, Sato N.
- Journal Title
  
  Alcohol Clin Exp Res. 29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Ethanol-induced sensitization to endotoxin in Kupffer cells is dependent upon oxidative stress.2005
- Author(s)
  Yamashina S, Takei Y, Ikejima K, Enomoto N, Kitamura T, Sato N.
- Journal Title
  
  Alcohol Clin.Exp.Res. 29(12 Suppl)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Role of leptin in pathogenesis of NASH.2005
- Author(s)
  Ikejima K, Lang T, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  In NASH and Nutritional Therapy. (Tokyo : Springer-Verlag) (Okita K, Ed.)
  
  Pages: 44-49
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Smad and p38 MAPK signaling pathways independently regulate α1(I) collagen gene expression in unstimulated and TGF-β stimulated hepatic stellate cells.2005
- Author(s)
  Tsukada S, Westwick JK, Ikejima K, Sato N, Rippe RA.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 10055-10064
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] The role of leptin in progression of non-alcoholic fatty liver disease.2005
- Author(s)
  Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N.
- Journal Title
  
  Hepatol.Res. 33(2)
  
  Pages: 151-154
- NAID
  10016809329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Targeted gene delivery to sinusoidal endothelial cells : DNA nanoassociate bearing hyaluronan-glycocalyx.2004
- Author(s)
  Takei Y, Maruyama A, Ferdous A, Nishimura Y, Kawano S., Ikejima K, Okumura S., Asayama S, Nogawa M, Hashimoto M, Makino Y, Kinoshita M, Watanabe S, Akaike T, Lemasters JJ, Sato N.
- Journal Title
  
  FASEB J. (10.1096/fj.03-0494fje, published on line February 20, 2004) 18
  
  Pages: 699-701
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] NASHの病態2004
- Author(s)
  竹井謙之, 池嶋健一, 佐藤信紘
- Journal Title
  
  日本消火器病学会誌 101
  
  Pages: 1194-1203
- NAID
  10014292099
- Data Source
  KAKENHI-PROJECT-14657136
[Journal Article] Genetic manipulation of liver sinusoidal endothelial cells.2004
- Author(s)
  Takei Y, Ikejima K, Enomoto N, Maruyama A, Sato N.
- Journal Title
  
  In Organ Microcirculation : A gateway to diagnostic and therapeutic interventions. (Springer-Verlag, Tokyo ) (Ishii H, Ed.)
  
  Pages: 129-134
- NAID
  10012736253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Senescence marker protein-30 (SMP3O) regulates Akt activity and contributes to cell survival in Hep G2 cells.2004
- Author(s)
  Matsuyama S, Kitamura T, Zheng D, Fujita T, Ishigami A, Handa S, Maruyama N, Enomoto N, Ikejima K, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 321
  
  Pages: 386-390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] 肝炎の発癌-サイトカインの役割2004
- Author(s)
  池嶋健一, 佐藤信紘
- Journal Title
  
  Surgery Frontier 11
  
  Pages: 44-48
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] アルコール性肝障害におけるレプチンの役割2004
- Author(s)
  池嶋健一, 佐藤信紘
- Journal Title
  
  消化器科 38
  
  Pages: 575-579
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Yakei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004
- Author(s)
  Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Comparative Hepatology3 (Suppl I) S12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004
- Author(s)
  Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Comparative Hepatology 3(Suppl I)
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-alpha in isolated rat Kupffer cells and exerts hepatoprotective effects in mice.2004
- Author(s)
  Ishizaki-Koizumi S, Sonaka I, Takei Y, Ikejima K, Sato N.
- Journal Title
  
  Biochem Biophys Res Commun. 322
  
  Pages: 514-519
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lant T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Burn injury sensitizes rat Kupffer cells via mechanisms dependent on gut-derived endotoxin.2004
- Author(s)
  Enomoto N, Takei Y, Yamashina S, Fukuda T, Suzuki S, Ikejima K, Kitamnra T, Sato N.
- Journal Title
  
  J.Gastroenterol. 39
  
  Pages: 1175-1181
- NAID
  10014091735
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004
- Author(s)
  Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Comparative Hepatology 3(Suppl I)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-α in isolated rat Kupffer cells and exerts hepatoprotective effects in mice.2004
- Author(s)
  Ishizaki-Koizumi S, Sonaka I, Takei Y, Ikejima K, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun 322
  
  Pages: 514-519
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] NASHの病態2004
- Author(s)
  竹井謙之, 池嶋健一, 砂防信紘
- Journal Title
  
  日本消化器病学会雑誌 101
  
  Pages: 1194-1203
- NAID
  10014292099
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Effect of PPAR-γ agonist on transdifferentiation of hepatic stellate cells.2004
- Author(s)
  Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K. et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Data Source
  KAKENHI-PROJECT-14657136
[Journal Article] Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor.2004
- Author(s)
  Lang T, Ikejima K, Yoshikawa M, Enomoto N, Iijima K, Kitamura T, Yakei Y, Sato N.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 323
  
  Pages: 1091-1095
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Expression of leptin receptors in hepatic sinusoidal cells.2004
- Author(s)
  Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N.
- Journal Title
  
  Comparative Hepatology 3(SupplI)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] Thalidomide prevents alcoholic liver injury in rats through inhibition of Kupffer cell sensitization.2004
- Author(s)
  Enomoto N, Takei Y, Hirose M, Ikejima K, Kitamura T, Sato N.
- Journal Title
  
  Comparative Hepatology 3(Suppl I)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] NASHの病因:酸化ストレスとサイトカインの関与2004
- Author(s)
  竹井謙之, 池嶋健一, 佐藤信紘
- Journal Title
  
  肝臓 45
  
  Pages: 77-81
- NAID
  10012915441
- Data Source
  KAKENHI-PROJECT-16590633
[Journal Article] Targeted Gene delivery to sinusoidal endothelial cells : DNA nanoassociate bearing hyaluronan-glycocalyx.2004
- Author(s)
  Takei Y, Maruyama A, Ferdous A, Nishimura Y, Kawano S, Ikejima K, Okumura S, Asayama S, Nogawa M, Hashimoto M, Makino Y, Kinoshita M, Watanabe S, Akaike T, Lemasters JJ, Sato N.
- Journal Title
  
  FASEBJ. 18
  
  Pages: 699-701
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390235
[Journal Article] 特集肥満へのアプローチ肥満症・メタボリックシンドロームの治療・管理(合併症の診断と治療)非アルコール性脂肪性肝炎(NASH)
- Author(s)
  池嶋健一, 渡辺純夫
- Journal Title
  
  治療 90(5)
  
  Pages: 1727-1732
- Data Source
  KAKENHI-PROJECT-19590791
[Journal Article] Orthotopic Hepatocellular Carcinoma Model with a Controlled and Reproducible Tumorigenicity.
- Author(s)
  Okubo H, Takei Y, Serizawa N, Enomoto N, Ikejima K, Sato N.
- Journal Title
  
  J Gastro Heaptol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Journal Article] Genetic Manipulation of Liver Sinusoidal Endothelial Cells.
- Author(s)
  Takei Y, Ikejima K, Enomoto N, Maruyama A, Sato N.
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- NAID
  10012736253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590690
[Presentation] 糖尿病治療と脂肪肝の新たな関係 SLD 診療アップデート2024
- Author(s)
  今一義、内山明、佐藤寿史、深田浩大、山科俊平、池嶋健一
- Organizer
  第100回　練馬区医師会学術部糖尿病治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K07402
[Presentation] Fatty acid desaturase 2 rs174583 genetic variant is involved in advanced fibrosis in fatty liver disease.2023
- Author(s)
  Ikejima S, Kon K, Ikejima K, et al.
- Organizer
  The Liver Meeting, American Association for the Study of Liver Disease (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] The role of lipid dynamics in steatotic liver disease2023
- Author(s)
  Kazuyoshi Kon
- Organizer
  KASL（韓国肝臓病学会）Single Topic Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07402
[Presentation] The trends of acute hepatitis A and hepatitis E during the COVID-19 pandemic in Japan.2023
- Author(s)
  Hiroo Fukada, Kazuyoshi Kon, Satoshi Sakuma, Toshifumi Sato, Maki Morinaga, Toshifumi Yamagata, Akira Uchiyama, Reiko Yaginuma, Kyoko Fukuhara, Shunhei Yamashina, Kenichi Ikejima.
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) 2023 Taipei
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] The effect of glycine on phospholipids / sphingolipids composition during hepato-carcinogenesis in hepatocyte-specific PTEN knockout mice2023
- Author(s)
  Kazuyoshi Kon, Hyeon-Cheol Lee-Okada, Kumiko Arai, Akira Uchiyama, Toshifumi Sato, Hiroo Fukada, Takehiko Yokomizo, Kenichi Ikejima
- Organizer
  AASLD（米国肝臓病学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07402
[Presentation] A selective PPARα modulator pemafibrate reduced palmitic acid-induced lipotoxicity via induction of autophagy.2023
- Author(s)
  Shunhei Yamashina, Satoshi Sakuma, Toshifumi Sato, Hiroo Fukada, Hisafumi Yamagata, Akira Uchiyama, Reiko Yaginuma, Kyoko Fukuhara, Kazuyoshi Kon, Kenichi Ikejima.
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) 2023 Taipei
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Downregulation of fatty acid desaturase 2 exacerbates murine steatohepatitis caused by high-fat and high-cholesterol diet2023
- Author(s)
  Kazuyoshi Kon, Hyeon-Cheol Lee-Okada, Kumiko Arai, Akira Uchiyama, Toshifumi Sato, Hiroo Fukada, Shunhei Yamasina, Takehiko Yokomizo, Kenichi Ikejima
- Organizer
  DDW（米国消化器病学会週間）2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07402
[Presentation] リピドミクス解析による脂肪性肝疾患病態形成プロセスの考察2023
- Author(s)
  今一義，福原京子，池嶋健一
- Organizer
  日本肝臓学会西部会　Symposium 2-10
- Data Source
  KAKENHI-PROJECT-23K07402
[Presentation] Diagnosis of Perihepatitis and Fitz-Hugh-Curtis Syndrome by Laparoscopy: An Unusual Condition for Right Hypochondriac Pain and Liver Injury?2023
- Author(s)
  Shunsuke Ikejima, Akira Uchiyama, Maki Morinaga, Hiroo Fukada, Hisafumi Yamagata, Reiko Yaginuma, Kyoko Fukuhara, Kazuyoshi Kon, Shunhei Yamashina, Kenichi Ikejima.
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) 2023 Taipei
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Prevention of Liver Carcinogenesis by Glycine in Hepatocyte-specific PTEN Knockout Mice2023
- Author(s)
  Kazuyoshi Kon, Kumiko Arai, Maki Morinaga, Reiko Yaginuma, Toshifumi Sato, Akira Uchiyama, Kenichi Ikejima
- Organizer
  APASL（アジア太平洋肝臓学会）Oncology 2023 Workshop 4
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07402
[Presentation] Downregulation of fatty acid desaturase 2 exacerbates murine steatohepatitis caused by high-fat and high-cholesterol diet.2023
- Author(s)
  Kon K, Lee-Okada HC, Arai K, Uchiyama A, Sato T, Fukada H, Yamashina S, Ikejima K.
- Organizer
  Digestive Disease Week 2023.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] High-fat diet exacerbates lipopolysaccharide-induced liver injury in obese KK-Ay mice.2023
- Author(s)
  Sakuma S, Kon K, Ikejima K, et al.
- Organizer
  International Liver Congress, the European Association for the Study of the Liver (EASL)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] High-fat diet increases susceptibility to lipopolysaccharide-induced liver injury in obese KK-Ay mice.2023
- Author(s)
  Sakuma S, Kon K, Ikejima K, et al.
- Organizer
  The Liver Meeting, American Association for the Study of Liver Disease (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] The impact of alteration in hepatic lipid metabolism on the progression of steatotic liver disease2023
- Author(s)
  Kazuyoshi Kon, Kenichi Ikejima
- Organizer
  The 3rd JSH International Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07402
[Presentation] Downregulation of fatty acid desaturase 2 exacerbates murine steatohepatitis caused by high-fat and high-cholesterol diet.2023
- Author(s)
  Kon K, Lee-Okada HC, Ikejima K, et al.
- Organizer
  Digestive Disease Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] The impact of decreased expression of fatty acid desaturase 2 on the progression of steatotic liver disease2023
- Author(s)
  Kazuyoshi Kon, Akira Uchiyama, Kenichi Ikejima
- Organizer
  JDDW（日本消化器病学会週間）Panel Discussion 5-5
- Data Source
  KAKENHI-PROJECT-23K07402
[Presentation] Glycine prevents murine autoimmune cholangitis and pancreatitis induced by double-stranded RNA through modulation of innate immune responses.2023
- Author(s)
  Uchiyama A, Kon K, Ikejima K, et al.
- Organizer
  The Liver Meeting, American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Emerging concept of steatotic liver disease comprising alcohol and metabolic disfunction.2023
- Author(s)
  Ikejima K.
- Organizer
  3rd Japan Society of Hepatology International Liver Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] 脂肪肝炎形成の分子機構とジェントロジー．2022
- Author(s)
  今一義，石塚敬，池嶋健一．
- Organizer
  合同シンポジウム1（日本肝臓学会）「脂質異常症と脂肪肝のクロストーク」．第54回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] Perihepatitis and Fitz-Hugh-Curtis syndrome: an unusual condition for upper abdominal pain and liver injury?2022
- Author(s)
  Akira Uchiyama, Kazuyoshi Kon, Hiroo Fukada, Maki Morinaga, Reiko Yaginuma, Kyoko Fukuhara, Shunhei Yamashina, Kenichi Ikejima.
- Organizer
  American Association for the Study of Liver Disease (AASLD) The Liver Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Amino acid glycine suppresses steatohepatitis and tumorigenesis in hepatocyte-specific phosphatase and tensin homolog knockout mice.2022
- Author(s)
  Kon K, Arai K, Uchiyama A, Fukada H, Sato T, Morinaga M, Fukuhara K, Yaginuma R, Yamashina S, Ikejima K.
- Organizer
  International Liver Congress 2022 of the European Association for the Study of the Liver (EASL).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] Type I and type II natural killar T cells are involved in the development of steatohepatitis in elder mice.2022
- Author(s)
  Kazuyoshi Kon, Eisuke Nakadera, Kumiko Arai, Akira Uchiyama, Hiroo Fukada, Toshifumi Sato, Reiko Yaginuma, Kyoko Okumura, Shunhei Yamashina, Kenichi Ikejima.
- Organizer
  Digestive Disease Week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Glycine supplementation inhibits steatohepatitis-related liver carcinogenesis in hepaticyte-specific PTEN deficient mice.2022
- Author(s)
  Kazuyoshi Kon, Kumiko Arai, Akira Uchiyama, Reiko Yaginuma, Toshifumi Sato, Shunhei Yamashina, Kenichi Ikejima
- Organizer
  American Association for the Study of Liver Disease (AASLD) The Liver Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Glycine supplementation inhibits steatohepatitis-related liver carcinogenesis in hepatocyte-specific PTEN deficient mice.2022
- Author(s)
  Kon K, Arai K, Uchiyama A, Yaginuma R, Sato T, Yamashina S, Ikejima K.
- Organizer
  American Association for the Study of Liver Disease (AASLD) The Liver Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] Updates on pathogenesis of alcohol-associated liver disease2022
- Author(s)
  Ikejima K
- Organizer
  the Asian Pcific Association for the Study of Liver (APASL) 2022 Seoul
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Glycine prevents steatohepatitis-related carcinogenesis in hepatocyte-specific phosphatase and tensin homolog-deficient mice.2022
- Author(s)
  Kazuyoshi Kon, Kumiko Arai, Akira Uchiyama, Hiroo Fukada, Toshifumi Sato, Maki Morinaga, Kyoko Fukuhara, Reiko Yaginuma, Shunhei Yamashina, Kenichi Ikejima
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) Oncology 2022 Takamatsu
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Role of gut-liver axis and innate immunity in the pathogenesis of alcohol-related liver disease.2022
- Author(s)
  Akira Uchiyama, Kenichi Ikejima
- Organizer
  The 2nd World Congress on Alcohol and Alcoholism, Cracow, Poland
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] 肝細胞特異的PTENノックアウトマウスにおけるグリシンの脂肪肝炎・肝がん抑制効果．2021
- Author(s)
  今一義、山科俊平、池嶋健一．
- Organizer
  第22回JDDW（第25回日本肝臓学会大会）ワークショップ11．
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] Glycine ameliorates steatohepatitis via reduction of oxidative stress in hepatocyte-specific PTEN-deficient mice.2021
- Author(s)
  K Kon, A Uchiyama, H Fukada, E Nakadera, R Yaginuma, K Fukuhara, S Yamashina, K Ikejima.
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference. Molecular and Cell Biology of the Liver: Recent Evolution to Clinical Application, Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Accumulation of autophagy-specific substrate p62/SQSTM1 are associated with the formation of multinucleated cells in liver cancer2021
- Author(s)
  S Yamashina, E Nakadera, H Fukada, A Uchiyama, R Yaginuma, K Fukuhra, K Kon, K Ikejima.
- Organizer
  American Association for the Study of Liver Disease (AASLD) The Liver Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Amino acid prevents tumorigenesis via ameliorating steatohepatitis in hepatocyte-specific phosphatase and tensin homolog knockout2021
- Author(s)
  K Kon, K Arai, A Uchiyama, H Fukada, E Nakadera, M Morinaga, K Fukuhara, R Yaginuma, S Yamashina, K Ikejima.
- Organizer
  American Association for the Study of Liver Disease (AASLD) The Liver Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] アミノ酸グリシンによる脂肪肝炎の改善効果―肝特異的PTENノックアウトマウスを用いた検討－2021
- Author(s)
  今一義、新井久美子、内山明、深田浩大、中寺英介、山科俊平、池嶋健一
- Organizer
  第58回　日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] Glycine ameliorates steatohepatitis via reduction of oxidative stress in hepatocyte-specific PTEN-deficient mice.2021
- Author(s)
  Kon K, Arai K, Uchiyama A, Fukada H, Nakadera E, Yaginuma R, Fukuhara K, Yamashina S, Ikejima K.
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] 肝細胞特異的PTENノックアウトマウスにおけるグリシンの脂肪肝炎・肝がん抑制効果2021
- Author(s)
  今一義，山科俊平，池嶋健一
- Organizer
  Japan Digestive Disease Week 2021
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] Type I and type II NKT cells additively exacerbates steatohepatitis caused by high-fat and high-cholesterol diet in aged mice.2021
- Author(s)
  E Nakadera, K Kon, K Arai, H Fukada, A Uchiyama, S Yamashina, K Ikejima.
- Organizer
  American Association for the Study of Liver Disease (AASLD) The Liver Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] Hyperactivation of immune response following modulation of small intestinal microbiome causes exacerbation of alcoholic liver injury in female KK-Ay mice.2021
- Author(s)
  K Kon, A Uchiyama, H Fukada, E Nakadera, R Yaginuma, K Fukuhara, S Yamashina, K Ikejima.
- Organizer
  20th Congress of the International Society for Biomedical Research on Alcoholism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07922
[Presentation] 肝特異的PTEN欠損脂肪肝炎モデルマウスにおけるアミノ酸グリシンの効果2021
- Author(s)
  今一義，山科俊平，池嶋健一
- Organizer
  第107回　日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] Amino acid prevents tumorigenesis via ameliorating steatohepatitis in hepatocyte-specific phosphatase and tensin homolog knockout mice.2021
- Author(s)
  Kon K, Arai K, Uchiyama A, Fukada H, Nakadera E, Morinaga M, Fukuhara K, Yaginuma R, Yamashina S, Ikejima K.
- Organizer
  American Association for the Study of Liver Disease (AASLD) The Liver Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] アミノ酸グリシンによる脂肪肝炎の改善効果―肝特異的PTENノックアウトマウスを用いた検討－．2021
- Author(s)
  今一義、新井久美子、内山明、深田浩大、中寺英介、山科俊平、池嶋健一．
- Organizer
  第58回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K08315
[Presentation] KK-Ayマウスアルコール性肝炎モデルにおけるリファキシミンの小腸細菌叢再構築を介した肝障害抑制効果．2019
- Author(s)
  北川隆太、今一義、池嶋健一．
- Organizer
  JDDW2019 （第61回日本消化器病学会大会), ンポジウム7-3
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] The role of intestinal microbiota in alcoholic liver disease.2019
- Author(s)
  Kitagawa R, Kon K, Ikejima K.
- Organizer
  the 17th Congress of the European Society for Biomedical Research on Alcoholism (ESBRA).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] Endoplasmic reticulum stress and oxidative stress in alcoholic liver injury comorbid metabolic syndrome.2019
- Author(s)
  Kon K, Suzuki M, Ikejima K.
- Organizer
  the 17th Congress of the European Society for Biomedical Research on Alcoholism (ESBRA).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] Aging causes the exacerbation of dietary steatohepatitis accompanied by muscle weakness in mice.2019
- Author(s)
  Ishizuka K, Kon K, Arai K, Uchiyama A, Yamashina S, Ikejima K.
- Organizer
  Digestive Disease Week2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] アルコール性肝炎発症における小胞体－ミトコンドリアストレスの関与．2019
- Author(s)
  今一義、内山明、池嶋健一．
- Organizer
  第19回抗加齢医学会総会.
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] 高脂質負荷による脂肪性肝炎と脂質組成変化における加齢の影響．2019
- Author(s)
  石塚敬、今一義、池嶋健一．
- Organizer
  第105回日本消化器病学会総会．シンポジウム 8
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] 加齢における脂肪肝炎の増悪と骨格筋萎縮の病態メカニズム2019
- Author(s)
  石塚敬, 今一義, 内山明, 深田浩大, 山科俊平, 池嶋健一．
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] Age-related enhancement of cellular stresses and lipotoxicity exacerbates dietary steatohepatitis in mice.2019
- Author(s)
  Ishizuka K, Kon K, Lee HC, Arai K, Uchiyama A, Fukuo H, Yamashina S, Yokomizo T, Ikejima K.
- Organizer
  American Association for the Study of Liver Disease (AASLD) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] 脂肪性肝炎の肝内脂質組成変化における加齢の影響2019
- Author(s)
  石塚　敬、今　一義、池嶋健一
- Organizer
  第105回日本消化器病学会総会　シンポジウム8
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] 加齢に伴う脂質代謝変化による食事誘発性脂肪性肝炎の増悪機序．2019
- Author(s)
  石塚敬、今一義、池嶋健一．
- Organizer
  第55回日本肝臓学会総会．パネルディスカッション 7-6
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] アルコール性肝障害マウスにおける小腸内細菌叢の変化と肝障害に与える影響．2019
- Author(s)
  今一義、北川隆太、深田浩大、内山明、山科俊平、池嶋健一．
- Organizer
  第56回日本消化器免疫学会総会．シンポジウム１
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] AGING CAUSES THE EXACERBATION OF DIETARY STEATOHEPATITIS ACCOMPANIED BY MUSCLE WEAKNESS IN MICE2019
- Author(s)
  Kei Ishizuka, Kazuyoshi Kon, Kumiko Arai, Akira Uchiyama, Shunhei Yamashina, and Kenichi Ikejima
- Organizer
  DDW 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] リファキシミンによる小腸細菌叢の変化を介したアルコール性肝障害抑制効果：肥満KK-Ay マウスを用いた検討．2019
- Author(s)
  北川隆太、今一義、池嶋健一．
- Organizer
  第55回日本肝臓学会総会．ワークショップ8
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] リファキシミンを用いた腸内細菌叢の制御によるメタボリック＋アルコール性脂肪肝炎の抑制効果．2019
- Author(s)
  北川隆太、今一義、内山明、山科俊平、池嶋健一．
- Organizer
  アルコール・アディクション医学会総会
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] 加齢による非アルコール性脂肪肝炎の増悪機序―高齢マウスを用いた検討―2018
- Author(s)
  石塚敬、今一義、青山友則、内山明、山科俊平、池嶋健一、渡辺純夫
- Organizer
  第104回　日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] 加齢による非アルコール性脂肪肝炎の増悪機序―高脂肪負荷高齢マウスを用いた検討―2018
- Author(s)
  石塚敬、今一義、青山友則、内山明、山科俊平、池嶋健一
- Organizer
  第22回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] Aging-dependent alterations in hepatic fatty acid metabolism exacerbate murine dietary steatohepatitis through enhancing lipotoxicity2018
- Author(s)
  Kei Ishizuka, Kazuyoshi Kon, Kumiko Arai, Akira Uchiyama, Tomonori Aoyama, Shunhei Yamashina, and Kenichi Ikejima
- Organizer
  AASLD 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] L-carnitine changes hepatic lipid composition and prevents lipotoxicity in hign-fat diet-fed KK-Ay mice.2017
- Author(s)
  Kon K, Ikejima K, Uchiyama A, Arai K, Aoyama T, Yamashina S, Watanabe S.
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] The formation of P62-positive inclusion body is associated with macrophage polarization in non-alcohoic fatty liver disease.2017
- Author(s)
  Fukushima H, Yamashina S, Arakawa A, Taniguchi G, Aoyama T, Uchiyama A, Kon K, Ikejima K, Watanabe S.
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Female hormone enhances hepatic innate and autoimmune responses against double-stranded RNA.2017
- Author(s)
  Uchiyama A, Ikejima K, Someya S, Arai K, Aoyama T, Kon K, Yamashina S, Watanabe S.
- Organizer
  the Liver Meeting 2017 (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Glycine minimizes murine autoimmune cholangitisand pancreatitis caused by double-stranded RNA through modulation of innate immune response.2017
- Author(s)
  Uchiyama A, Ikejima K, Kon K, Arai K, Fukuhara K, Aoyama T, Yamashina S, Watanabe S 演題名 GLYCINE MINIMIZES MURINE AUTOIMMUNE CHOLANGITIS AND PANCREATITIS CAUSED BY DOUBLE-STRANDED RNA THROUGH MODULATION OF INNATE IMMUNE RESPONSES 学会名
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Aging exacerbates high-fat diet-induced steatohepatitis through blunting of lipid metabolic response in mice2017
- Author(s)
  Ishizuka K, Kon K, Ikejima K, Suzuki M, Arai K, Uchiyama A, Aoyama T, Yamashina S, Watanabe S.
- Organizer
  AASLD annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09440
[Presentation] Aging exacerbates high-fat diet-induced steatohepatitis through blunting of lipid metabolic response in mice.2017
- Author(s)
  Ishizuka K, Kon K, Ikejima K, Suzuki M, Arai K, Uchiyama A, Aoyama T, Yamashina S, Watanabe S.
- Organizer
  the Liver Meeting 2017 (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] 自己免疫性胆管病変マウスモデルにおける性差の解析2016
- Author(s)
  染谷秀忍，池嶋健一，内山明，鈴木麻衣子，青山友則，今一義，山科俊平，渡辺純夫
- Organizer
  JDDW2016
- Place of Presentation
  神戸
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Real-world efficacy of antiviral treatment using a combination of daclatasvir and asnaprevir in Japanese patients of chronic hepatitis C2016
- Author(s)
  Ikejima K, Fukuhara K, Aoyama T, Uchiyama A, Kon K, Yamashina S, Watanabe S
- Organizer
  HCV2016
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] NAFLD・NASHの病態形成と自然免疫2016
- Author(s)
  池嶋健一
- Organizer
  第53回日本消化器免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2016-07-14
- Invited
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Metabolic disease and NASH2016
- Author(s)
  Ikejima K, Kon K, Yamashina S, Watanabe S
- Organizer
  25th Conference of the Asian Pacific Association for the Study of the Liver
- Place of Presentation
  Tokyo
- Year and Date
  2016-02-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] 非アルコール性脂肪肝炎（NASH）の病態形成におけるリピドラフトの役割2016
- Author(s)
  内山　明、池嶋健一、渡辺純夫
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  幕張
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K09022
[Presentation] Gender-specific development of experimental autoimmune cholangitis induced by double-stranded RNA2016
- Author(s)
  Someya S, Ikejima K, Uchiyama A, Arai K, Kon K, Aoyama T, Yamasina S, Watanabe S
- Organizer
  The Liver Meeting 2016 (AASLD)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Efficacy of denosumab on progression of osteoporosis in autoimmune liver diseases2016
- Author(s)
  Ikejima K, Yaginuma R, Kon K, Aoyama T, Uchiyama A, Yamashina S, Watanabe S
- Organizer
  The Liver Meeting 2016 (AASLD)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Immuno-nutritional approach for impaired glucose tolerance in metabolic steatohepatitis through modulation of Kupffer cell function2015
- Author(s)
  Ikejima K, Kon K, Watanabe S
- Organizer
  第23回日本消化器関連学会週間（JDDW）
- Place of Presentation
  Tokyo
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Steatohepatitis syndromeの共通病態基盤としてのKupffer細胞極性変化と免疫栄養的制御2015
- Author(s)
  池嶋健一，今一義，渡辺純夫
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Contribution of regulatory T cells in pathogenesis of nonalcoholic steatohepatitis in mice2015
- Author(s)
  Ikejima K, Yokokawa J, Arai K, Uchiyama A, Kon K, Yamashina S, Watanabe S
- Organizer
  18th International Symposium on the Cells of Hepatic Sinusoid
- Place of Presentation
  Asilomar, CA, USA
- Year and Date
  2015-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] Dietary glycine improves impaired glucose tolerance by modulating polarization of Kupffer cells in diabetic KK-Ay mice.2015
- Author(s)
  Ikejima K, Arai K, Kon K, Uchiyama A, Yamashina S, Watanabe S
- Organizer
  Digestive Disease Week
- Place of Presentation
  Washington DC, USA
- Year and Date
  2015-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09023
[Presentation] L-carnitine improves high-fat diet-induced steatohepatitis through insulin sensitization and regulation of lipid metabolism2014
- Author(s)
  Kon K, Ikejima K, Kusama H, Morinaga M, Arai K, Uchiyama A, Aoyama T, Yamashina S, Watanabe S.
- Organizer
  米国肝臓病学会（AASLD）
- Place of Presentation
  米国　ボストン
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] メタボリックシンドロームモデルKK-Ayマウスにおけるアミノ酸による免疫調節2014
- Author(s)
  池嶋健一，高嶋志在，渡辺純夫
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] The chemical chaperon 4-phenylbutyrate prevents epigenetic alterations and carcinogenesis in NASH-HCC model mice.2014
- Author(s)
  Kazuyoshi Kon, Kenichi Ikejima, Akira Uchiyama, Tomonori Aoyama, Kumiko Arai, Maki Morinaga, Shunhei Yamashina and Sumio Watanabe
- Organizer
  49th annual meeting of EASL the international liver congress.
- Place of Presentation
  London
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] 脂肪性肝炎の病態形成における小胞体ストレスの役割2014
- Author(s)
  今一義、池嶋健一、渡辺純夫
- Organizer
  平成26年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] Dietary supplementation of glycine ameliorates diabetic steatohepatitis in KK-Ay mice through immune-metabolic regulation2014
- Author(s)
  Ikejima K, Takashima S, Arai K, Kon K, Yamashina S, Watanabe S
- Organizer
  Digestive Disease Week
- Place of Presentation
  Chicago
- Year and Date
  2014-05-03
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] SUPPRESSION OF ENDOPLASMIC RETICULUM STRESS BY CHEMICAL CHAPERON INHIBITS CARCINOGENESIS IN STEATOHEPATITIS-RELATED HCC MODEL MICE2014
- Author(s)
  Kon K, Ikejima K, Arai K, Morinaga M, Kusama H, Uchiyama A, Aoyama T, Yamashina S, Watanabe S.
- Organizer
  ISBRA 2014 World Congress
- Place of Presentation
  米国　ベルビュー
- Year and Date
  2014-06-23
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] ストレプトゾトシン／高脂肪食による脂肪性肝炎由来肝発癌モデルの解析と化学シャペロンによる効果の検討2014
- Author(s)
  今一義、池嶋健一、内山明、山科俊平、渡辺純夫
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] Ursolic acid ameliorates murine cholangitis induced by double-stranded RNA2014
- Author(s)
  Ikejima K, Arai K, Uchiyama A, Kon K, Yamashina S, Watanabe S.
- Organizer
  European Association for the Study of the Liver
- Place of Presentation
  London
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] Glycine prevents maturity-onset obesity and metabolic steatohepatitis in diabetic KK-Ay mice through modulation of hepatic innate immunity2013
- Author(s)
  Ikejima K, Takashima S, Arai K, Kon K, Yamashina S, Watanabe S
- Organizer
  Digestive Diesase Week
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] The effect of chemical chaperon on progression of steatohepatitis in a mouse model of steatohepatitisrelated HCC.2013
- Author(s)
  今一義.池嶋健一.森永真紀.内山明.青山友則.山科俊平.渡辺純夫.
- Organizer
  Japan Liver Cell Week
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] The expression of autophagy-related proteins in non-B non-C hepatocellular carcinogenesis.2013
- Author(s)
  Kon K.Ikejima K.Uchiyama A.Yamashina S.Kawasaki S.Watanabe S.
- Organizer
  Digestive Disease Week2013（DDW2013）
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] Hepatic regulatory T Cells contribute to the development of dietary steatohepatitis in mice.2013
- Author(s)
  Yokokawa J, Ikejima K, Arai K, Kon K, Yamashina S, Watanabe S
- Organizer
  American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] Ursolic acid minimizes cholestatic liver injury in common bile duct-ligated rats2013
- Author(s)
  Ikejima K, Arai K, Kon K, Yamashina S, Watanabe S
- Organizer
  European Association for the Study of the Liver
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] 化学シャペロンによる脂肪性肝炎の病態抑制効果－脂肪性肝炎由来肝癌モデルマウスを用いた検討－.2013
- Author(s)
  今一義.池嶋健一.内山明.山科俊平.渡辺純夫.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] 非アルコール性脂肪性肝疾患患者におけるオートファジー機能障害とカテプシン発現異常2013
- Author(s)
  福生有華,山科俊平,泉光輔,園上浩司,荒川敦,青山友則,内山明,今一義,鈴木聡子,池嶋健一,渡辺純夫
- Organizer
  肝臓(0451-4203)54巻Suppl.1 PageA146
- Data Source
  KAKENHI-PROJECT-23590989
[Presentation] Long term efficacy and safety of low-dose pioglitazone treatment for nonalcoholic fatty liver disease with insulin resistance2013
- Author(s)
  Ikejima K, Fukuhara K, Yaginuma R, Kon K, Yamashina S, Suzuki S, Watanabe S
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) Liver Week 2013
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] 非B非C肝癌におけるオートファジー関連の白の発現と臨床像.2013
- Author(s)
  今一義.池嶋健一.渡辺純夫.
- Organizer
  第21回日本消化器関連学会週間(JDDW2013)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] 非アルコール性脂肪性肝疾患患者におけるオートファジー機能障害とカテプシン発現異常2013
- Author(s)
  福生有華, 山科俊平, 泉光輔, 園上浩司, 荒川敦, 青山友則, 内山明, 今一義, 鈴木聡子, 池嶋健一, 渡辺純夫
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24390191
[Presentation] 非B非C肝発癌におけるオートファジー関連蛋白の関与.2013
- Author(s)
  今一義.池嶋健一.渡辺純夫.
- Organizer
  第99回日本消化器病学会総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] 肝発癌におけるPtenおよびP62発現と背景肝疾患による相違の検討.2013
- Author(s)
  今一義.池嶋健一.川崎誠治.渡辺純夫.
- Organizer
  第49回日本肝癌研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] NAFLD患者における肝カテプシンL発現とオートファジー機能の評価福生有華2012
- Author(s)
  山科俊平,泉光輔,稲見義宏,山形寿文,今一義,鈴木聡子,池嶋健一,渡辺純夫
- Organizer
  肝臓(0451-4203)53巻Suppl.3 PageA929
- Data Source
  KAKENHI-PROJECT-23590989
[Presentation] Innate immune responses involving NK and NKT cells promote liver regeneration after partial hepatectomy2011
- Author(s)
  Hosoya S, Ikejima K, Arai K, Kon K, Yamashina S, Takeda K, Watanabe S
- Organizer
  Poster Session(Poster of Distinction), The Liver Meeting 2011(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Loss of parkin impairs liver regeneration2011
- Author(s)
  Fukada H, Yamashina S, Izumi K, Nakadera E, Fukuo Y, Uchiyama A, Kon K, Ikejima K, Watanabe S
- Organizer
  Poster Session, The Liver Meeting 2011(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Hepatic NKT cells are progressively depleted in steatohepatitis with tumorigenesis caused by hepatocyte-specific PTEN deficiency2011
- Author(s)
  Miyaji T, Ikejima K, Hosoya S, Arai K, Kon K, Yamashina S, Watanabe S
- Organizer
  Poster Session, The Liver Meeting 2011(Annual Meeting of Am Ass ociation for Study of Liver Diseases)
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 肝5-11NASHの肝病態に対するウルソール酸の有用性:モデルマウスでの検討.シンポジウム5NASH発症の分子機構と治療標的2011
- Author(s)
  池嶋健一, 今一義, 渡辺純夫
- Organizer
  第15回日本肝臓学会大会(JDDW2011)
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Imaired liver regeneration after partial hepatectomy in mice depleting NK and NKT cells2011
- Author(s)
  Hosoya S, Ikejima K, Arai K, Aoyama T, Kon K, Ishikawa S, Yamagata H, Yamashina S, Suzuki S, Takeda K, Watanabe S
- Organizer
  Poster Session, 18th International Symposium on Cells of the Hepa Sin usoid(Biannual Meeting of International Society for Hepatic Sinusoidal Research)
- Place of Presentation
  Florence, Italy
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 脂肪性肝炎発症におけるNKT細胞の関与.ワークショップ7 : Steatohepatitis(脂肪肝炎)の病態～その多様性と相同性～2011
- Author(s)
  池嶋健一, 山形寿文, 渡辺純夫
- Organizer
  第97回日本消化器病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 脂肪肝における低酸素暴露後のZone 3優位の酸化ストレスと肝細胞アポトーシス2011
- Author(s)
  今一義, 池嶋健一, 谷口源太郎, 内山明, 福原京子, 細谷聡子, 山科俊平, 渡辺純夫
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 肝細胞内脂肪滴蓄積とオートファジー機能障害2011
- Author(s)
  山科俊平、稲見義宏、今一義、池嶋健一、渡辺純夫
- Organizer
  第47回日本肝臓学会総会ワークショップ
- Place of Presentation
  東京都ホテルグランパシフィック
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21390234
[Presentation] Mice depleting natural killer T cells are more susceptible to dietary-induced steatohepatitis, Selected Oral Presentation 102011
- Author(s)
  Ikejima K, Yamagata H, Arai K, Ishikawa S, Hosoya S, Kon K, Yamashina S, Suzuki S, Takeda K, Watanabe S
- Organizer
  18th International Symposium on Cells of the Hepatic Sinusoid(Biannual Meeting of International Society for Hepatic Sinusoidal Research)
- Place of Presentation
  Florence, Italy
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Mice depleting natural killer T cells are more susceptible to dietary-induced steatohepatitis2011
- Author(s)
  Ikejima K
- Organizer
  16^<th> International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Florence, Italy
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 肝細胞内脂肪滴蓄積とオートファジー機能障害.ワークショップ2 NASH-我が国の実態と発生機序の解明に向けて2011
- Author(s)
  山科俊平, 稲見義宏, 今一義, 池嶋健一, 渡辺純夫
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Ursolic acid ameliorates hepatic fibrogenesis through induction of apoptosis in hepa Ses sion : Fibrogenesis Experimental2011
- Author(s)
  Ikejima K, WFukuhara K, Hosoya S, Yamashina S, Watanabe S
- Organizer
  The International Liver Congress 2011 : 46th Annual Meeting of the European Association for the Study of the Liver(EASL)
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Differential role of natural killer T cell subsets in xenobiotics-induced hepatic inflammation and fibrogenesis2011
- Author(s)
  Ikejima K, Ishikawa S, Hosoya S, Yamagata H, Arai K, Kon K, Yamashina S, Watanabe S
- Organizer
  Poster Session(Poster of Distinction), Digestive Disease Week
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] アセトアミノフェン投与後の肝細胞死誘導に対する関与について.アセトアミノフェン投与後の肝細胞死誘導に対する関与について2011
- Author(s)
  井草祐樹, 山科俊平, 今一義, 池嶋健一, 渡辺純夫
- Organizer
  アセトアミノフェン投与後の肝細胞死誘導に対する関与について
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] High-carbohydrate diet containing trans-fatty acid induces severe steatohepatitis via the enhancement of endoplasmic reticulum stress in KK-Ay mice2010
- Author(s)
  Saito H, Kon K, Ishikawa S, Hosoya S, Arai K, Takashima M, Yamashina S, Ikejima K, Watanabe S
- Organizer
  Poster Session, The 45th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Vienna, Austria
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Impaired hepatic innate responses involving NKT cells in obese diabetic KK-Ay mice2010
- Author(s)
  Yamagata H, Ikejima K, Ishikawa S, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
- Organizer
  Poster Session I Steatohepatitis-NASH, 15^<th> Int ernational Symposium on Cells of International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Pasadena, CA, USA
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 肝NKT細胞とCD1d分子による脂肪性肝炎の発症制御メカニズムの解析.ワークショップ3 : NASH/NAFLD発症のメカニズム2010
- Author(s)
  池嶋健一, 山形寿文, 渡辺純夫
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Trans-fatty acid induces apoptosis of hepatocytes by enhancement of oxidative stress in steatotic liver of KK-Ay mice2010
- Author(s)
  Kon K, Ikejima K, Saito H, Ishikawa S, Hosoya S, Arai K, Okumura K, Yamashina S, Watanabe S
- Organizer
  Poster Session, The Liver Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 非B非C原発性肝癌の腫瘍マーカーと背景疾患からみた検討.ワークショップ4 :慢性肝疾患からの発癌:背景肝疾患(病理,画像,遺伝子異常を含む)からみた検討2010
- Author(s)
  今一義, 池嶋健一, 渡辺純夫
- Organizer
  第14回日本肝臓学会大会(JDDW 2010)
- Place of Presentation
  横浜
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] チオアセタミド誘発性肝障害におけるCD1d拘束性NKT細胞の役割2010
- Author(s)
  石川幸子, 池嶋健一, 山形寿文, 青山友則, 今一義, 渡辺純夫
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] アセトアミノフェン投与後肝障害におけるオートファジーの役割の検討2010
- Author(s)
  井草祐樹, 山科俊平, 今一義, 池嶋健一, 渡辺純夫
- Organizer
  第14回日本肝臓学会大会(JDDW 2010)
- Place of Presentation
  横浜
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] MRIによるfat fraction+T2 starを用いた肝脂肪化および鉄含有量の定量的評価2010
- Author(s)
  福原京子, 池嶋健一, 渡辺純夫
- Organizer
  第38回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Adipocytokines and NASH. Symposium 2 : NASH-Current insights in pathogenesis and clinical aspects. Part 2. Pathogenesis of NASH2010
- Author(s)
  Ikejima K
- Organizer
  The Japanese Society of Gastroenterology(JSGE) 2nd International Forum 2. Emerging Issues in AIH & NASH
- Place of Presentation
  Niigata, Japan
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] CD1d-restricted natural killer T cells contribute to thioacetamide-induced he inf lammation and fibrogenesis in mice2010
- Author(s)
  Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
- Organizer
  Parallel Session 11 : Chronic liver injury and fibrosis, The 45th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Vienna, Austria
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] アセトアミノフェン投与後肝障害におけるオートファジーの役割の検討2010
- Author(s)
  井草祐樹、山科俊平、今一義、池嶋健一、渡辺純夫
- Organizer
  第18回日本消化器関連学会週間
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-20590797
[Presentation] NASHに関する最近の話題.特別企画【最近の話題】22010
- Author(s)
  池嶋健一
- Organizer
  第38回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Hepatic steatosis suppresses autophagic proteolysis. Poster Session2010
- Author(s)
  Yamashina S, Inami Y Ikejima K, Watanabe S
- Organizer
  2010 International Society for Bi Alc oholism(ISBRA) World Congress
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Depletion of natural killer T cells increases the susceptibility to dietary-induced steatohepatitis in mice2010
- Author(s)
  Ikejima K, Yamagata H, Arai K, Ishikawa S, Hosoya S, Kon K, Yamashina S, Takeda K, Watanabe S
- Organizer
  Poster Session, The Liver Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] ジエチルニトロソアミン投与後肝障害におけるオートファジーの関与について2010
- Author(s)
  米合古麗阿不都雪克, 山科俊平, 深田浩大, 井草祐樹, 今一義, 池嶋健一, 渡辺純夫
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 脂肪性肝炎発症における肝NKT細胞とCD1d分子の関与.パネルディスカッション: NASH/NAFLDの病因・病態と予後2010
- Author(s)
  池嶋健一, 山形寿文, 渡辺純夫
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] CD1d-restricted natural killer T cells modulate susceptibility to dietary-induced steatohepatitis in mice2010
- Author(s)
  Ikejima K, Yamagata H, Ishikawa S, Arai K, Aoyama T, Kon K, Takeda K, Watanabe S
- Organizer
  Poster Session, The 45th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Vienna, Austria
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 脂肪性肝炎の病態形成におけるトランス脂肪酸の影響と酸化ストレスの役割.ワークショップ7,肝病態形成におおける酸化ストレスの意義2010
- Author(s)
  今一義, 池嶋健一, 細谷聡子, 斉藤紘昭, 石川幸子, 柳沼礼子, 山科俊平, 渡辺純夫
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  新潟
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Adipocytokines and NASH.2010
- Author(s)
  Ikejima K
- Organizer
  第96回日本消化器病学会総会第2回国際フォーラム(English Session)
- Place of Presentation
  新潟
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Contribution of hepatic steatosis and adipokines in resistance formation to the current anti-virral therapy for chronic hepatitis C2010
- Author(s)
  Ikejima K
- Organizer
  BIT's 1st World Congress of Virus and Infections(WCVI)-2010
- Place of Presentation
  Busan, South Korea
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Loss of autophagy enhances the sensitization of Kupffer cells to endo toxin2010
- Author(s)
  Hiroo Fukada, Shunhei Yamashina, Kousuke Izumi, Yoshihiro Inami, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
- Organizer
  The American association for the study of liver diseases 61th annual meeting and postgraduate course# 1971
- Place of Presentation
  米国ボストンHynes convention center
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21390234
[Presentation] Innate immunity and NAFLD/NASH. Session 4 : Immunity and cytokine responses in NASH2010
- Author(s)
  Ikejima K, Yamagata H, Hosoya S, Ishikawa S, Aoyama T, Kon K, Yamashina S, Suzuki S, Watanabe S
- Organizer
  The 9th Japan Society of Hepatology(JSH) Single Topic Conference NASH-2010
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Loss of autophagy enhances the sensitization of Kupffer cells to endotoxin2010
- Author(s)
  Fukada H, Yamashina S, Izumi K, Inami Y, Kon K, Ikejima K, Watanabe S
- Organizer
  Poster Session Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Loss of autophagy enhances acetaminophen-induced liver injury2010
- Author(s)
  Igusa Y, Yamashina S, Izumi K, Fukada H, Mikirai A, Inami Y, Kon K, Ikejima K, Watanabe S
- Organizer
  AASLD Poster Session, Digestive Disease Week(DDW)
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Contribution of NK and NKT cells in hepatic regeneration after partial hepatectomy in mice2010
- Author(s)
  Hosoya S, Ikejima K, Aoyama T, Ishikawa S, Yamagata H, Kon K, Takeda K, Watanabe S
- Organizer
  Poster Session, The 45th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Vienna, Austria
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Hepatic NKT and NK cells regulate liver reg hep atectomy in mice2010
- Author(s)
  Hosoya S, Ikejima K, Aoyama T, Ishikawa S, Yamagata H, Kon K, Yamashina S, Takeda K, Watanabe S
- Organizer
  Poster Session, The Liver Meeting 2010(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Contribution of CD1d-restricted natural killer T cells to xenobiotics-induced hepatic inflammation and fibrogenesis in mice2010
- Author(s)
  Ikejima K, Ishikawa S, Yamagata H, Aoyama T, Kon K, Arai K, Takeda K, Watanabe S
- Organizer
  Session II. Steatohepatitis-II(Oral presentation), 15th International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Pasadena, CA, USA
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Ursolic acid ameliorates dietary steatohepatitis in obese diabetic KK-Ay mice2010
- Author(s)
  Ikejima K, Piao N, Yamagata H, Kon K, Yamashina S, Watanabe S
- Organizer
  AASLD Poster Session, Digestive Disease Week(DDW)
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Synthetic triglyceride containing an arachidonic acid branch(8A8) minimizes endotoxin-induced liver injury2010
- Author(s)
  Ikejima K, Piao N, Kon K, Aoyama T, Yamashina S, Takei Y, Sato N, Watanabe S
- Organizer
  Poster Session, 2010 International Society for Biomedical Research on Alcoholism(ISBRA) World Congress
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] チオアセタミド肝障害の病態形成におけるNKT細胞の関与.ワークショップ12 :肝疾患における免疫病態形成と新たな治療戦略2010
- Author(s)
  池嶋健一, 石川幸子, 渡辺純夫
- Organizer
  第14回日本肝臓学会大会
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] NAFLDの病態進展における肝内自然免疫機構の関与:メタボリックシンドロームモデル動物を用いた検討ワークショップ12 : NAFLDの経時的進展2009
- Author(s)
  池嶋健一, 山形寿文, 渡辺純夫
- Organizer
  第95回日本消化器病学会総会
- Place of Presentation
  札幌
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] HBs抗原陰性・HCV抗体陰性の肝細胞癌における臨床的特徴と腫瘍マーカー測定の重要性2009
- Author(s)
  今一義, 池嶋健一, 青山友則, 山形寿文, 柳沼礼子, 石川幸子, 高島基樹, 山科俊平, 鈴木聡子, 渡辺純夫
- Organizer
  第95回日本消化器病学会総会
- Place of Presentation
  札幌
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] NAFLD関連肝細胞癌の治療にかかわる因子の解明-腫瘍マーカー測定の重要性-ワークショップ1 : NASHは声明予後に影響するか?2009
- Author(s)
  今一義, 池嶋健一, 渡辺純夫
- Organizer
  第13回日本肝臓学会大会(JDDW 2009)
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] NAFLD患者の低用量ピオグリタゾン療法におけるMRI肝脂肪測定の有用性2009
- Author(s)
  柳沼礼子, 池嶋健一, 福原京子, 青山友則, 今一義, 山科俊平, 鈴木聡子, 渡辺純夫
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Lipid accumulation inhibits induction of autophagy in the mouse liver2009
- Author(s)
  Inami Y, Yamashina S, Izumi K, Fukada H, Kon K, Ikejima K, Watanabe S
- Organizer
  Poster Session, The Liver Meetin Am erican Association for Study of Liver Diseases
- Place of Presentation
  Boston, USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Lipid accumulation inhibits induction of autophagy in the mouse liver2009
- Author(s)
  Yoshihiro Inami, Shunhei Yamashina, Kousuke Izumi, Hiroo Fukada, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
- Organizer
  The American association for the study of liver diseases 60th annual meeting and postgraduate course# 1875
- Place of Presentation
  日米国ボストンHynes convention center
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21390234
[Presentation] 肝内自然免疫系による非アルコール性脂肪性肝炎発症感受性の調節,パネルディスカッション11 :自然免疫と消化器疾患2009
- Author(s)
  池嶋健一, 山形寿文, 渡辺純夫
- Organizer
  第13回日本肝臓学会大会(JDDW 2009)
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Ezetimibe prevents metabolic syndrome-related steatohepatitis exacerbated by trans-fatty acid in KK-Ay mice. Poster Session2009
- Author(s)
  Kon K, Ikejima K, Aoyama T, Ishikawa S, Hosoya S, Arai K, Yamashina S, Watanabe S
- Organizer
  The Liver Meeting 2009(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Obese diabetic KK-Ay mice are resistant to NKT cell-mediated liver injury induced by a-galactosylceramide2009
- Author(s)
  Ikejima K, Yamagata H, Takeda K, Aoyama T, Kon K, Yamashina S, Suzuki S, Watanabe S
- Organizer
  Poster S The 44th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] メタボリックシンドロームモデルKK-Ayマウスにおける肝内NKT細胞分画異常に対するピオグリタゾンの影響2009
- Author(s)
  山形寿文, 池嶋健一, 青山友則, 今一義, 山科俊平, 渡辺純夫
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 脂肪性肝炎形成における肝細胞内貯蔵鉄の役割-マウス初代培養肝細胞を用いた検討-ワークショップ1, NASH・NAFLDの礎2009
- Author(s)
  今一義, 池嶋健一, 青山友則, 山形寿文, 内山明, 高島基樹, 石川幸子, 柳沼礼子, 山科俊平, 鈴木聡子, 渡辺純夫
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Increased susceptibility to ethanol-induced liver injury in genetically diabetic KK-Ay mice2009
- Author(s)
  Ikejima K, Kon K, Yamagata H, Aoyama T, Yamashina S, Suzuki S, Watanabe S
- Organizer
  AASLD Poster Session, D Di sease Week(DDW)
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Adipokine regulation of innate immunity and tissue repair in steatohepatitis2009
- Author(s)
  Ikejima K
- Organizer
  The 4th international symposium on alcoholic liver and pancreatic disease and cirrhosis
- Place of Presentation
  Hurghada
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Thioacetamide-induced hepatic fibrogenesis is ameliorated in mice genetically disruptive of CD1d2009
- Author(s)
  Ishikawa S, Ikejima K, Yamagata H, Aoyama T, Kon K, Takeda K, Watanabe S
- Organizer
  Poster Session,(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, USA
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Adipokine regulation of innate immunity and tissue repair in steatohepatitis2009
- Author(s)
  Ikejima K
- Organizer
  The 4^<th> international symposium on alcoholic liver and pancreatic disease and cirrhosis
- Place of Presentation
  Hurghada, Egypt
- Year and Date
  2009-10-08
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] C型慢性肝炎のインターフェロン治療効果規定因子としての肝脂肪化およびアディポカイン発現.パネルディスカッション6 : C型肝炎治療の最前線2009
- Author(s)
  柳沼礼子, 池嶋健一, 渡辺純夫
- Organizer
  第95回日本消化器病学会総
- Place of Presentation
  札幌
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] He viral response to peg an d ribavirin therapy in Japanese patients with chronic hepatitis C. Poster Session2009
- Author(s)
  Yaginuma R, Ikejima K, Aoyama T, Yamagata H, Ishikawa S, KonK, Yamashina S, Suzuki S, Watanabe S
- Organizer
  The 44th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] 脂肪性肝炎の病態進展における肝内自然免疫機構の関与-メタボリックシンドロームモデルKK-Ayマウスを用いた検討2009
- Author(s)
  池嶋健一, 山形寿文, 石川幸子, 今一義, 渡辺純夫
- Organizer
  第46回日本消化器免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Pioglitazone improves abnormal expression of hepatic NKT cells in obese and diabetic KK-Ay mice2009
- Author(s)
  Ikejima K, Yamagata H, Takeda K, Kon K, Aoyama T, Yamashina S, Watanabe S
- Organizer
  Poster session Conference on NAFLD/NASH and related metabolic disease
- Place of Presentation
  Bologna, Italy
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] メタボリックシンドロームモデルKK-Ayマウスにおける肝内NKT細胞分画異常のメカニズム解析.ワークショップ3 :免疫担当細胞異常からみた肝疾患の病態2009
- Author(s)
  山形寿文, 池嶋健一, 渡辺純夫
- Organizer
  第13回日本肝臓学会大会(JDDW 2009)
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Pioglitazone restores expression and function of hepatic NKT cells in obese and diabetic KK-Ay mice2009
- Author(s)
  Yamagata H, Ikejima K, Takeda K, Aoyama T, Kon K, Yamashina S, Watanabe S
- Organizer
  Poster Session, The 44 meeting of the European Association for the Study of the Liver
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] C型肝炎ウイルス複製におけるニコチンの作用2009
- Author(s)
  山科俊平, 高島基樹, 青山友則, 柳沼礼子, 今一義, 鈴木聡子, 池嶋健一, 佐藤信紘, 渡辺純夫
- Organizer
  ポスターセッション,第13回日本肝臓学会大会(JDDW 2009)
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] C型慢性肝炎のペグインターフェロンα-2b・リバビリン併用療法のガイドライン準拠率と治療奏効性の関連2009
- Author(s)
  柳沼礼子, 池嶋健一, 青山友則, 山形寿文, 石川幸子, 今一義, 山科俊平, 鈴木聡子, 渡辺純夫
- Organizer
  ポスターセッション,第13回日本肝臓学会大会(JDDW 2009)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Pioglitazone prevents apoptosis of hepatic NKT cells in obese and diabetic KK-Ay mice2009
- Author(s)
  Yamagata H, Ikejima K, Takeda K, Kon K, Aoyama T, Yamashina S, Watanabe S
- Organizer
  Poster Session,(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] Pioglitazone minimizes regeneration failure following partial hepatectomy in obese KK-A^y mice. Poster Session2008
- Author(s)
  Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Yamagata H, Yamashina S, Watanabe S
- Organizer
  The Liver Meeting2008 (Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  San Francisco
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] C-reactive protein attenuates experimental hepatic fibrosis through inhibition of hepatic stellate cells transactivation. Poster Session2008
- Author(s)
  Ikejima K, Arai K, Kon K, Aoyama T, Okumura K, Yaginuma R, Yamashina S, Watanabe S
- Organizer
  The 43^<rd> annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] Efficacy of low-dose pioglitazone for the treatment of NAFLD patients in Japan2008
- Author(s)
  Yaginuma R, Ikejima K, Kon K, Okumura K, Yamashina S, Suzuki S, Watanabe S
- Organizer
  Poster Session, The Liver Meeting 2009 on(Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  Boston, USA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] メタボリックシンドロームにおける肝内参加ストレス応答性更新とそのメカニズム. パネルディスカッション22008
- Author(s)
  今一義, 池嶋健一, 渡辺純夫
- Organizer
  日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] 肝細胞の脂肪沈着とネクローシスに対するトランス脂肪酸の影響. ポスター2008
- Author(s)
  今一義, 池嶋健一, 青山友則, 山形寿文, 内山明, 柳沼礼子, 山科俊平, 渡辺純夫
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] C reactive protein(CRP)の肝星細胞活性化抑制を介した抗肝線維化作用. 口演2008
- Author(s)
  池嶋健一, 今一義, 青山友則, 山形寿文, 柳沼礼子, 山科俊平, 鈴木聡子, 渡辺純夫
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] TRAIL Receptor DR5-mediated apoptosis signals induce screlosing cholangiopathy in mice2008
- Author(s)
  Ikejima K, Takeda K, Kojima Y, Aoyama T, Okumura K, Yamashina S, Okumura K, Watanabe S
- Organizer
  AASLD Research Forum, Digestive Disease Week
- Place of Presentation
  San Diego, USA
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] C型慢性肝炎における肝脂肪化およびアディポカイン発現とペグインターフェロン・リバビリン併用療法奏効性. シンポジウム22008
- Author(s)
  池嶋健一, 柳沼礼子, 渡辺純夫
- Organizer
  日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] Altered expression and function of hepatic NKT cells in obese and diabetic KK-A^y mice.2008
- Author(s)
  Yamagata H, Ikejima K, Takeda K, Aoyama T, kon K, Yamashina S, Watanabe S.
- Organizer
  Liver Meeting 2008 (AASLD)
- Place of Presentation
  San Francisco
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] Altered expression andfunction of hepatic NKT cells in obese and diabetic KK-Ay mice. Parallel Session2008
- Author(s)
  Yamagata H, Ikejima K, Takeda K, Aoyama T, Kon K, Yamashina S, Watanabe S
- Organizer
  The Liver Meeting 2008 (Annual Meeting of AmericanAssociation for Study of LiverDiseases)
- Place of Presentation
  San Francisco
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] 癌抑制蛋白PTENの肝星細胞活性化に対する抑制効果. ワークショップ82008
- Author(s)
  高島基樹, 池嶋健一, 塚田重城, 今一義, 金野朗, 山科俊平, 鈴木聡子, 渡辺純夫
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] 硬化性胆管病変形成におけるTRAIL系免疫機構の役割 : TRAILおよびDR5遺伝子欠損マウスを用いた検討. ワークショップ102008
- Author(s)
  池嶋健一, 竹田和由, 渡辺純夫
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-09
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] NAFLDに対する低用量ピオグリタゾン投与の有用性. シンポジウム82008
- Author(s)
  池嶋健一, 柳沼礼子, 渡辺純夫
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-08
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] ジェノタイプ1b型高ウイルス量のC型慢性肝炎におけるpeg-interferon/ribavirin併用療法の宿主側難治性要因 : 肝脂肪化との関連について. 口演2008
- Author(s)
  鈴木聡子, 池嶋健一, 高島基樹, 水井智和, 山形寿文, 青山友則, 内山明, 柳沼礼子, 今一義, 金野朗, 山科俊平, 松本俊治, 渡辺純夫
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] KKAyマウスの肝再生不全に対するpioglitazoneの改善作用とそのメカニズム. ワークショップ12008
- Author(s)
  青山友則, 池嶋健一, 渡辺純夫
- Organizer
  第50回日本消化器病学会大会(JDDW2008)
- Place of Presentation
  東京
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] NAFLD治療におけるピオグリタゾン投与用量の検討 : 低用量投与の有用性について. ポスター2008
- Author(s)
  柳沼礼子, 池嶋健一, 福原京子, 青山友則, 今一義, 水井智和, 山科俊平, 鈴木聡子, 渡辺純夫
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] Acetaminophen induces severe liver injury caused by increased susceptibility to oxidative stress in obese KK-Ay mice. Poster Session2008
- Author(s)
  Kon K, Ikejima K, Aoyama T, Arai K, Yamashina S, Watanabe S
- Organizer
  The 43^<rd> annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] Involvement of iron in trans-fatty acid-induced accumulation and oxidative stress in mouse hepatocytes. Poster Session2008
- Author(s)
  Kon K, Ikejima K, Aoyama T, Yamagata H, Arai K, Yamashina S, Watanabe S
- Organizer
  The LiverMeeting 2008 (Annual Meeting of American Association for Study of Liver Diseases)
- Place of Presentation
  San Francisco
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] メタボリック症候群における肝再生不全 : pioglitazoneによる改善効果とそのメカニズムの検討2008
- Author(s)
  青山友則, 池嶋健一, 今一義, 山形寿文, 柳沼礼子, 山科俊平, 渡辺純夫
- Organizer
  第44回肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] NASHの発症・進展におけるC-reactive protein(CRP)の病態生理的意義2007
- Author(s)
  池嶋健一, 柳沼礼子, 渡辺純夫
- Organizer
  第11回肝臓学会大会
- Place of Presentation
  神戸
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19590791
[Presentation] The role of adipokines in hepatic fibrogenesis in alcoholic and nonalcoholic fatty liver diseases.2006
- Author(s)
  Ikejima K, Okumura K, Kon K, Aoyama T, Yamashina S, Enomoto N, Takei Y, Sato N
- Organizer
  International Society of Biomedical Research on Alcoholism (ISBRA)
- Place of Presentation
  Sydney, Australia
- Year and Date
  2006-09-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390213
[Presentation] Liver disorders associated with metabolic syndrome : disease susceptibility and therapeutic resistance.2006
- Author(s)
  Ikejima K
- Organizer
  The 32nd Autumn Congress of Korean Diabetic association.
- Place of Presentation
  Gyeongju, Korea
- Year and Date
  2006-11-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390213
[Presentation] 非B非C肝発癌におけるオートファジー関連蛋白の関与.
- Author(s)
  今一義.池嶋健一.渡辺純夫
- Organizer
  第99回日本消化器病学会総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] フェニル酪酸によるNASH肝発癌抑制効果－NASH発癌モデルマウスを用いた検討.
- Author(s)
  今一義.池嶋健一.渡辺純夫.
- Organizer
  第20回JDDW
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] Hepatic steatosis suppresses mitochondrial autophagy
- Author(s)
  Yamashina S, Inami Y, Uchiyama A, Kon K, Ikejima K, Watanabe S
- Organizer
  Poster Session 1 : Animal Models and Pathogenesis-1, 6th International Symposium on Alcoholic Liver and Pancreatic Diseases Cirrohosis
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-21590859
[Presentation] The chemical chaperon 4-phenylbutyrate prevents epigenetic alterations and carcinogenesis in NASH-HCC model mice
- Author(s)
  Kon K, Ikejima K, Uchiyama A, Aoyama T, Arai K, Morinaga M, Yamashina S, Watanabe S
- Organizer
  欧州肝臓学会（EASL)
- Place of Presentation
  イギリス　ロンドン
- Year and Date
  2015-04-09 – 2015-04-13
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] The chemical chaperon 4-phenylbutyrate inhibits liver fibrosis and tumorgenesis in high -fat diet with N-acetyI-β-D-glucosaminedase inhibitor-induced NASH model mice.
- Author(s)
  Kon K.Ikejima K.Hosoya S.Arai K.Uchiyama A.Yamashina S.Watanabe S.
- Organizer
  DDW
- Place of Presentation
  米国サンディエゴ
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] Role of NK and NKT cells in the pathogenesis and carcinogenesis in steatohepatitis.
- Author(s)
  Ikejima, K, Miyaji T, Hosoya S, Arai K, Kon K, Yamashina S, Watanabe S.
- Organizer
  16th Congress of International Society for Biomedical Research on Alcoholism
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] Induction of apoptosis in hepatic stellate cells as a treatment strategy for hepatic fibrosis.
- Author(s)
  Ikejima K, Wang X, Arai K, Kon K, Yamashina S, Watanabe S.
- Organizer
  16th Congress of International Society for Biomedical Research on Alcoholism.
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] Mechanisms of fibrogenesis in NASH
- Author(s)
  Ikejima K.
- Organizer
  4th Kokata Liver Meeting
- Place of Presentation
  Kolkata, India
- Invited
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] Pathophysiological role of adipocytokines in the digestive system.
- Author(s)
  Ikejima K, Kon K, Yamashina S, Watanabe S.
- Organizer
  The 3rd Asian-Pacific Topic Conference
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] 脂肪性肝炎の共通病態基盤としての肝内自然免疫系の関与
- Author(s)
  池嶋健一，今一義，山科俊平，渡辺純夫
- Organizer
  第12回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24590996
[Presentation] The expression of autophagy-related proteins in non-B non-C hepatocellular carcinogenesis
- Author(s)
  Kazuyoshi Kon, Kenichi Ikejima, Akira Uchiyama, Shunhei Yamashina, Sumio Watanabe
- Organizer
  DDW
- Place of Presentation
  米国オーランド
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] 非B非C肝癌におけるPtenおよびP62の発現の変化
- Author(s)
  今一義.池嶋健一.内山明.山形寿文.細谷聡子.高嶋志在.鈴木聡子.山科俊平.渡辺純夫.
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  石川県
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] The chemical chaperone 4-phenylbutyric acid attenuates trans-fatty acid-induced ER stress and hepatic lipotoxicity.
- Author(s)
  Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe
- Organizer
  THE 3RD ASIAN-PACIFIC TOPIC CONFERENCE
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590995
[Presentation] Inhibition of endoplasmic reticulum stress by 4-phenylbutyrate prevents steatohepatitis progression and tumorigenesis in NASH-HCC model mice.
- Author(s)
  Kon K.Ikejima K.Uchiyama A.Arai K.Yamashina S.Watanabe S.
- Organizer
  AASLD
- Place of Presentation
  米国ボストン
- Data Source
  KAKENHI-PROJECT-24590995

1. KON Kazuyoshi (30398672)

# of Collaborated Projects: 12 results

# of Collaborated Products: 216 results
2. YAMASHINA Shunhei (30338412)

# of Collaborated Projects: 11 results

# of Collaborated Products: 102 results
3. TAKEI Yoshiyuki (10306954)

# of Collaborated Projects: 6 results

# of Collaborated Products: 41 results
4. WATANABE Sumio (20138225)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
5. ENOMOTO Nobuyuki (20348973)

# of Collaborated Projects: 5 results

# of Collaborated Products: 32 results
6. SATO Nobuhiro (90028358)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
7. HIROSE Miyoko (70266039)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. UENO Takashi (10053373)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
9. 李賢哲 (30758321)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
10. OGIHARA Tatuo (80011196)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. TAKEDA Kazuyoshi (80272821)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
12. 千葉麻子 (40532726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TSUKADA Shigeki (40420848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. KAWAKAMI Kyojiro (90589227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SUEMIZU Hiroshi (40332209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TERAI Takeshi (90245704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KITAMURA Tsuneo (20231285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. FUJITA Toshiko (00100131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OHKUSA Toshifumi (50160445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MARUYAMA Atsushi (40190566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
21. HORIE Yasuo (30282164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. OHSHIMA Shigetoshi (50375268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Uchiyama Akira (60529254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. 鈴木聡子 (20317431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 岩渕和久 (10184897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. TAKASHIMA Motoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. FUJIMURA Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 小野正文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 鎌田佳宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
30. 小池正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 福原武志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 横溝岳彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 福村由紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 中島淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 和田孝一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ikejima Kenichi 池嶋 健一

IKEJIMA Kenichi 池嶋 健一

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脂肪肝炎を基盤とする肝発癌過程におけるFGFファミリー分子の機能的関与Principal Investigator

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Immunonutritional approach for innate immune dysregulation in metabolic dysfunction-associated fatty liver diseasePrincipal Investigator

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Innate immune regulation in metabolic steatohepatitis and experimental therapeuticsPrincipal Investigator

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Innate immune regulation of hepatic metabolism and immuno-nutritional approach for nonalcoholic fatty liver diseasePrincipal Investigator

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Ikejima Kenichi 池嶋健一

IKEJIMA Kenichi 池嶋健一