Sakamoto Naoya 坂元尚哉

… Alternative Names

SAKAMOTO NAOYA 坂元尚哉

SAKAMOTO Naoya 坂元尚哉

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Researcher Number	20361115
Other IDs
External Links
Affiliation (Current)	2025: 東京都立大学, システムデザイン研究科, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 東京都立大学, システムデザイン研究科, 准教授 2015 – 2019: 首都大学東京, システムデザイン研究科, 准教授 2012: 川崎医療福祉大学, 医療技術学部, 准教授 2011: 東北大学, 工学(系)研究科(研究院), 助教 2007 – 2011: Tohoku University, Graduate School of Engineering, Assistant Professor … More 2008: 東北大学, 大学院・医工学研究科, 助教 2006: Tohoku University, Department of Bioengineering and Robotics, Research Associate 2006: 東北大学, 大学院工学研究科, 助手 2003 – 2004: 東北大学, 大学院・工学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Biomedical engineering/Biological material science / Basic Section 55030:Cardiovascular surgery-related / Science and Engineering / Biomedical engineering/Biomaterial science and engineering / Orthodontics/Pediatric dentistry / Biomedical engineering/Biological material science / Mechanobiology / Engineering / Science and Engineering
Keywords	Principal Investigator 細胞骨格 / 細胞核 / 生物・生体工学 / 細胞バイオメカニクス / メカノバイオロジー / 架橋タンパク質 / バイオメカニクス / 細胞・組織 / 重力 / 高重力 … More / 転写活性 / 細胞内張力 / LINC複合体 / 不均質性 / クロマチン / アクチン細胞骨格 / 翻訳 / permeability / migration / cellular interaction / atherosclerosis / shear stress / cocultured blood vessel model / smooth muscle cell / endothelial cell / 共存培養血管 / 流れ負荷 / 細胞共存型血管モデル / 物質透過性 / 遊走性 / 細胞間相互作用 / 動脈硬化症 / せん断応力 / 共存培養血管モデル / 平滑筋細胞 / 内皮細胞 / 細胞内力学伝達 / 細胞内力学伝達 / 生物生体工学 / 生物物理 / 細胞外基質分解酵素 / 血管内皮細胞 / リモデリング / 力学刺激 / 生体システム・フィジオーム … More Except Principal Investigator 細胞骨格 / 血管内皮細胞 / バイオメカニクス / 血管平滑筋細胞 / アクチンフィラメント / 内皮細胞 / ストレスファイバ / せん断応力 / 微細加工技術 / 力学伝達経路 / 細胞牽引力 / 細胞力学応答 / 平滑筋細胞 / マイクロポスト / 数値流体力学研究 / 壁せん断応力 / 共培養モデル / 細胞核 / 静水圧負荷 / メカノセンシング / Rhoファミリー / 細胞外基質 / メカノバイオロジー / ソフトリソグラフィー / マイクロマシニング / 粘弾性特性 / 遺伝子導入 / 焦点接着斑 / 慢性解離性大動脈瘤 / 慢性大動脈解離 / 血管内皮細胞-血管平滑筋細胞共培養 / nonA-nonB型大動脈解離 / 数値流体力学 / 大動脈瘤 / 先天性大動脈二尖弁 / 内皮細動－平滑筋細胞共培養モデル / 衝突噴流 / MMP / 壁剪断応力 / 大動脈二尖弁 / 大動脈拡大 / 単培養モデル / 数値流体力学計算 / 剪断応力 / 大動脈解離 / 細胞計測・操作 / DNA / 細胞バイオメカニクス / 骨 / LINC複合体 / 骨形成 / 細胞極性 / Actin dynamics / Micropost / Stress fiber / Intercellular mechanical balance / Vascular smooth muscle cells / Vascular endothelial cells / ひずみ速度依存性 / マイクロアレイ / 局所力学刺激 / アクチンダイナミクス / 細胞内力学バランス / Mechanotransduction / Micromachining / Stretching / Flow exposure / Gene transfection / Actin filaments / Focal adhesions / 近接場光 / 焦点接着班 / 葉状仮足 / 微小管 / せん断応力負荷 / 張力負荷 / メカノトランスダクション / 微細加工 / 伸展刺激 / 流れ刺激 / Endothelial cell / Tensile loading / Hydrostatic pressure / Shear stress / Response mechanism to mechanical stimuli / Actin filament / Integrin / Biomechanics / 局所ひずみ / FAT / GFP / 伸張負荷 / 引張負荷 / 力学的応答機構 / インテグリン / Db1ファミリー / Dblファミリー / 乳腺上皮細胞 / Rho-GEF / アクチン骨格 / マクロフルディクス / マクロウェル / バイオMEMS / バイオチップ / マイクロフルイディクス / マイクロウェル / 単一細胞診断 / 磁気駆動 / メカノセンサ / ストレスファイバー / 細胞内情報伝達 / 生体物性 / バイオイメージング / バイオテクノロジー / マイクロナノデバイス / 生物・生体工学 / シグナル伝達 / マイクロマシン / 非線形大変形 / ヒステリシスループ / ひずみ速度 / 非線形変形 / 引張試験装置 / ストレフファイバ / マイクロセンサアレイ / カンチレバー / ナノマシン加工技術 / 焦点接触 / 焦点接触力 Less

せん断応力負荷による血管平滑筋細胞の生体反応と大動脈解離偽腔拡大の関連性の検討
- Principal Investigator
  
  相澤啓
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
Elucidation of high gravity-sensing mechanisms in cells and its application to control cellular phenotype and differentiationPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO NAOYA
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo Metropolitan University
Patient specific assessment of hemodynamics by computational fluid dynamics in patients with acute non-A non-B aortic dissection
- Principal Investigator
  
  木村直行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
Influence of shear stress on human aortic endothelial cell/smooth muscle cell interaction in bicuspid aortic valve aortopathy
- Principal Investigator
  
  Kawahito Koji
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
Patient specific assessment of hemodynamics by computational fluid dynamics in patients with chronic aortic dissection
- Principal Investigator
  
  Kimura Naoyuki
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
Verification of local translational mechanism contributing to polarized cellular mechano-responsesPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO NAOYA
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo Metropolitan University
Study on the role of the mechanical dynamics in the nucleus in cellular mechanical responsesPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO NAOYA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Tokyo Metropolitan University
Study on the effects of the mechanical environment of the cell nucleus on the radiation resistance of cells
- Principal Investigator
  
  Nagayama Kazuaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Ibaraki University
The involvement of cell polarity in trabecular formation
- Principal Investigator
  
  KAMIOKA HIROSHI
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Okayama University
Study of the role of nuclear mechanical remodeling in cellular mechano-responsesPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO NAOYA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Metropolitan University
STUDY ON ROLE OF INTRACELLULAR FORCE TRANSMISSION VIA LINC COMPLEX IN CELL RESPONSESPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki University of Medical Welfare
  Tohoku University
Regulation mechanisms of mechanostress-induced actin cytoskeleton reorganzation
- Principal Investigator
  
  OHASHI Kazumasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Mechanobiology
- Research Institution
  Tohoku University
Fundamental Study for Development of An Engineering Model of Remodeling Mechanism of Blood Vessel Walls in Response to Mechanical EnvironmentPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tohoku University
Study of Mechanisms of Cellular Mechanosensing
- Principal Investigator
  
  SATO Masaaki
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Engineering
- Research Institution
  Tohoku University
磁気駆動マイクロピラーによる細胞外局所力学環境のアクティブ操作
- Principal Investigator
  
  大橋俊朗
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Development of Bioassay System with Microwell Slide Towards High throughput Single Cell Analysis
- Principal Investigator
  
  OHASHI Toshiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
細胞内シグナル伝達の動的制御による細胞マイクロマシンの創出
- Principal Investigator
  
  佐藤正明
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tohoku University
マトリックスデバイスによる細胞骨格の力学バランス計測と細胞機能制御
- Principal Investigator
  
  大橋俊朗
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
マイクロポストを用いた細胞の形態制御と力学伝達経路の解明
- Principal Investigator
  
  大橋俊朗
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tohoku University
細胞内ストレスファイバの力学特性計測と変形機構の解明
- Principal Investigator
  
  佐藤正明
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tohoku University
Study of roles of cytoskeletons in morphological responses of vascular endothelial cells to mechanical stimuli
- Principal Investigator
  
  SATO Masaaki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tohoku University
ナノマシン加工技術による内皮細胞焦点接触力の計測デバイスの開発
- Principal Investigator
  
  SATO Masaaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tohoku University
Mechanical dynamics of focal adhesions of vascular endothelial cells using nano-imaging
- Principal Investigator
  
  SATO Masaaki
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Study of the Effect of Hemodynamic Forces on Mechanism of Atherogenesis using Cocultured Blood Vessel ModelPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoya, 大橋俊朗
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tohoku University
Roles of Integrins of Endothelial Cells in Response to Mechanical Stimuli
- Principal Investigator
  
  SATO Masaaki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tohoku University

[Journal Article] A Compressed Collagen Construct for Studying Endothelial-Smooth Muscle Cell Interaction under High Shear Stress2022
- Author(s)
  Yuya Hiroshima, Yuki Oyama, Kaoru Sawasaki, Masanori Nakamura, Naoyuki Kimura, Koji Kawahito, Hiromichi Fujie, Naoya Sakamoto
- Journal Title
  
  Annals of Biomedical Engineering
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09154
[Journal Article] Compressed Collagen Construct for Studying Endothelial Smooth Muscle Cell Interaction Under High Shear Stress2022
- Author(s)
  Hiroshima Y, Oyama Y, Sawasaki K, Nakamura M, Kimura N, Kawahito K, Fujie H
- Journal Title
  
  Ann Biomed Eng.
  
  Volume: - Issue: 8 Pages: 951-963
- DOI
  10.1007/s10439-022-02972-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10763, KAKENHI-PROJECT-20K09154
[Journal Article] A 3D tissue model-on-a-chip for studying the effects of human senescent fibroblasts on blood vessels2021
- Author(s)
  Pauty Joris、Nakano Shizuka、Usuba Ryo、Nakajima Tadaaki、Johmura Yoshikazu、Omori Satotaka、Sakamoto Naoya、Kikuchi Akihiko、Nakanishi Makoto、Matsunaga Yukiko T.
- Journal Title
  
  Biomaterials Science
  
  Volume: 9 Issue: 1 Pages: 199-211
- DOI
  10.1039/d0bm01297a
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21497, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-18H03521, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-19K16177, KAKENHI-PROJECT-18H01793
[Journal Article] Intranuclear strain in living cells subjected to substrate stretching: A combined experimental and computational study2021
- Author(s)
  Tsukamoto Shingo、Asakawa Takumi、Kimura Shun、Takesue Naoyuki、Mofrad Mohammad R.K.、Sakamoto Naoya
- Journal Title
  
  Journal of Biomechanics
  
  Volume: 119 Pages: 110292-110292
- DOI
  10.1016/j.jbiomech.2021.110292
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Journal Article] Mechanical role of nesprin-1-mediated nucleus-actin filament binding in cyclic stretch-induced fibroblast elongation2017
- Author(s)
  N. Sakamoto, M. Ogawa, K. Sadamoto, M. Takeuchi, N. Kataoka
- Journal Title
  
  Cellular and Molecular Bioengineering
  
  Volume: 10 Issue: 4 Pages: 327-338
- DOI
  10.1007/s12195-017-0487-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01304, KAKENHI-PROJECT-16K15837
[Journal Article] Influence of shear stress on phenotype and MMP production of smooth muscle cells in a co-culture model2017
- Author(s)
  X. Han, N. Sakamoto, N. Tomita, H. Meng, M. Sato, M. Ohta
- Journal Title
  
  Journal of Biorheology
  
  Volume: 印刷中
- NAID
  130006394622
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01304
[Journal Article] Effect of low oxygen conditions on matrix metalloproteinase-9 production of macrophages subjected to cyclic stretching: involvement of ERK and Rho kinase pathways2017
- Author(s)
  N. Sakamoto, K. Sadamoto
- Journal Title
  
  JBSE
  
  Volume: 12 Issue: 1 Pages: 16-00590-16-00590
- DOI
  10.1299/jbse.16-00590
- NAID
  130005519962
- ISSN
  1880-9863
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01304, KAKENHI-PROJECT-16K15837
[Journal Article] Fluid shear stress combined with shear stress spatial gradients regulate vascular endothelial morphology2017
- Author(s)
  D. Yoshino, N. Sakamoto, M. Sato
- Journal Title
  
  Integrative Biology
  
  Volume: 9 Issue: 7 Pages: 584-594
- DOI
  10.1039/c7ib00065k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01304
[Journal Article] Role of paxillin in the early phase of orientation of the vascular endothelial cells exposed to cyclic stretching2012
- Author(s)
  Huang, W., Sakamoto, N., Miyazawa, M.R., Sato, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 418 Issue: 4 Pages: 708-713
- DOI
  10.1016/j.bbrc.2012.01.083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22616001
[Journal Article] Role of nesprin-1 in nuclear deformation in endothelial cells under static and uniaxial stretching conditions2012
- Author(s)
  T. Anno, N. Sakamoto, M. Sato
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: Vol. 424 Issue: 1 Pages: 94-99
- DOI
  10.1016/j.bbrc.2012.06.073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007, KAKENHI-PROJECT-22616001, KAKENHI-PROJECT-23650250
[Journal Article] Combined stimulation with cyclic stretching and hypoxia increases production of matrix metalloproteinase-9 and cytokines by macrophages2011
- Author(s)
  K.Oya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 412 Issue: 4 Pages: 678-682
- DOI
  10.1016/j.bbrc.2011.08.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007, KAKENHI-PROJECT-22616001
[Journal Article] Development of an endothelial-smooth muscle cell coculture model using phenotype-controlled smooth muscle cells2011
- Author(s)
  N.Sakamoto
- Journal Title
  
  Annals of Biomedical Engineering
  
  Volume: 39 Issue: 11 Pages: 2750-2758
- DOI
  10.1007/s10439-011-0372-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007, KAKENHI-PROJECT-22616001
[Journal Article] Role of intercellular junctions in redistribution of focal adhesions and orientation of vascular endothelial cells exposed to cyclic stretching2011
- Author(s)
  W-J. Huang, N. Sakamoto, K. Hanamura, R. Miyazawa, M. Sato
- Journal Title
  
  Cell. Molec. Bioeng.
  
  Volume: Vol. 4 Issue: 3 Pages: 368-378
- DOI
  10.1007/s12195-011-0194-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007
[Journal Article] Role of p120 catenin in the morphological changes of endothelial cells exposed to shear stress2010
- Author(s)
  N.Sakamoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 398 Pages: 426-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007
[Journal Article] Effect of spatial gradient in fluid shear stress on morphological changes in endothelial cells in response to flow.2010
- Author(s)
  N.Sakamoto, N, Saito, X.Han, T.Ohashi, M.Sato
- Journal Title
  
  Biochemical and Biophysical Research Communications Vol.395
  
  Pages: 264-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700457
[Journal Article] Direct measurement of shear strain in adherent vascular endothelial cells exposed to fluid shear stress.2010
- Author(s)
  Y.Ueki, N.Sakamoto, M.Sato
- Journal Title
  
  Biochem.Biophys.Res.Comm. 394
  
  Pages: 94-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007
[Journal Article] Role of p120-Catenin in the Morphological Changes of Endothelial Cells Exposed to Fluid Shear Stress2010
- Author(s)
  N.Sakamoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 398 Pages: 426-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700457
[Journal Article] Directmeasurement of shear strain in adherent vascular endothelial cells exposed to fluid shear stress.2010
- Author(s)
  Y.Ueki, N.Sakamoto, M.Sato
- Journal Title
  
  Biochemical and Biophysical Research Communications Vol.394
  
  Pages: 94-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700457
[Journal Article] Alteration of the material properties of the normal supra-spinatus tendon by nicotine treatment in a rat model2010
- Author(s)
  R.Ichinose, H.Sano, K.Kishimoto, N.Sakamoto, M.Sato, E.Itoi
- Journal Title
  
  Acta Orthopaedica Vol.81(5)
  
  Pages: 634-638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700457
[Journal Article] Cyclic force applied to FAs induces actin recruitment depending on the dynamic loading pattern.2010
- Author(s)
  Y.Ueki, N.Sakamoto, M.Sato
- Journal Title
  
  The Open Biomedical Engineering Journal Vol.4
  
  Pages: 129-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700457
[Journal Article] Measurements of strain on single stress fibers in living endothelial cells induced by fluid shear stress.2010
- Author(s)
  Y.Ueki, Y.Uda, N.Sakamoto, M.Sato
- Journal Title
  
  Biochemical and Biophysical Research Communications Vol.395
  
  Pages: 441-446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700457
[Journal Article] Effect of spatial gradient in fluid shear stress on morphological changes in endothelial cells in response to flow2010
- Author(s)
  N.Sakamoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 395 Pages: 264-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700457
[Journal Article] Direct meas- urement of shear strain in adherent vascular endothelial cells exposed to fluid shear stress2010
- Author(s)
  Y. Ueki, N. Sakamoto, M. Sato
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: Vol. 394 Issue: 1 Pages: 94-99
- DOI
  10.1016/j.bbrc.2010.02.115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007
[Journal Article] Effect of spatial gradient in fluid shear stress on morphological changes in endothelial cells in response to flow2010
- Author(s)
  N.Sakamoto
- Journal Title
  
  Biochemical and Biophysical Research Communications (未定, 印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007
[Journal Article] Role of p120 catenin in the morphological changes of endothelial cells exposed to shear stress2010
- Author(s)
  N. Sakamoto, K. Segawa, M. Kanzaki, T. Ohashi, M. Sato
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: Vol. 398 Issue: 3 Pages: 426-432
- DOI
  10.1016/j.bbrc.2010.06.092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007, KAKENHI-PROJECT-22590969
[Journal Article] A versatile micro- mechanical tester for actin stress fibers isolated from cells2009
- Author(s)
  T. S. Matsui, S. Deguchi, N. Sakamoto, T. Ohashi, M. Sato
- Journal Title
  
  Biorheology
  
  Volume: Vol. 46 Issue: 5 Pages: 401-415
- DOI
  10.3233/bir-2009-0551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007
[Journal Article] Morphological responses of vascular endothelial cells induced by local stretch transmitted through intercellular junctions2009
- Author(s)
  Y. Ueki, N. Sakamoto, T. Ohashi, M. Sato
- Journal Title
  
  Exp. Mech.
  
  Volume: Vol. 49 Issue: 1 Pages: 125-134
- DOI
  10.1007/s11340-008-9143-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20001007
[Journal Article] Effect of mechanical environment of focal adhesions on remodeling of endothelial cells subjected to cyclic stretching using microsubstrates2007
- Author(s)
  N. Sakamoto
- Journal Title
  
  Journal of Robotics and Mechatronics 19
  
  Pages: 557-564
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200030
[Journal Article] Effect of mechanical environment of focal adhesions on remodeling of endothelial cells subjected to cyclic stretch using microstructured substrate2007
- Author(s)
  N. Sakamoto
- Journal Title
  
  Journal of Robotics and Mechatronics 19
  
  Pages: 557-564
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Effect of mechanical environment of focal adhesionson remodeling of endothelial cells subjected to cyclic stretch using microstructured substrate2007
- Author(s)
  N. Sakamoto
- Journal Title
  
  Journal of Robotics and Mechatronics 19(5)
  
  Pages: 557-564
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Effect of Mechanical Environment of Focal Adhesions Remodeling of Endothelial Cells Subjected to Cyclic Stretching Using Microsubstrates2007
- Author(s)
  N. Sakamoto
- Journal Title
  
  Journal of Robotics and Mechatronics Vol.19
  
  Pages: 557-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18048005
[Journal Article] Effect of Mechanical Environment of Focal Adhesions on Remodeling of Endothelial Cells Subjected to Cyclic Stretching Using Microsubstrates2007
- Author(s)
  N. Sakamoto
- Journal Title
  
  Journal of Robotics and Mechatronics 19
  
  Pages: 557-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200030
[Journal Article] Effect of Mechanical Environment of Focal Adhesions on Remodeling of Endothelial Cells Subjected to Cyclic Stretching Using Microsubstrates2007
- Author(s)
  N. Sakamoto
- Journal Title
  
  Journal of Robotics and Mechatronics Vol.19
  
  Pages: 557-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18650119
[Journal Article] Nitric oxide production and smooth muscle cell phenotype of endothelial cell-smooth muscle cell cocultured model2006
- Author(s)
  N. Sakamoto
- Journal Title
  
  Journal of Biomechanical Science and Engineering 1
  
  Pages: 224-233
- NAID
  130000079545
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Nitric oxide production and smooth muscle cell phenotype of endothelial cell-smooth muscle cell cocultured model2006
- Author(s)
  N.Sakamoto
- Journal Title
  
  Journal of Biomechanical Science and Engineering 1
  
  Pages: 224-233
- NAID
  130000079545
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Nitric oxide production and smooth muscle cell phenotype of endothelial cell-smooth muscle cell cocultured model2006
- Author(s)
  N.Sakamoto
- Journal Title
  
  Journal of Biomechanical Science and Engineering 1
  
  Pages: 224-233
- NAID
  130000079545
- Data Source
  KAKENHI-PROJECT-17200030
[Journal Article] Nitric oxide production and smooth muscle cell phenotype of endothelial cell-smooth muscle cell cocultured model2006
- Author(s)
  N. Sakamoto
- Journal Title
  
  Journal of Biomechanical Science and Engineering 1
  
  Pages: 224-233
- NAID
  130000079545
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200030
[Journal Article] Effect of fluid shear stress on migration of vascular smooth muscle cells in cocultured model2006
- Author(s)
  N. Sakamoto
- Journal Title
  
  Annals of Biomedical Engineering 34
  
  Pages: 408-415
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Effect of fluid shear stress on migration of vascular smooth muscle cells in cocultured model2006
- Author(s)
  N.Sakamoto
- Journal Title
  
  Annals of Biomedical Engineering (in press)
- Data Source
  KAKENHI-PROJECT-17650125
[Journal Article] Effect of fluid shear stress on migration of vascular smooth muscle cells in cocultured model2006
- Author(s)
  N. Sakamoto
- Journal Title
  
  Annals of Biomedical Engineering 34
  
  Pages: 408-415
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200030
[Journal Article] Effect of fluid shear stress on migration of vascular smooth muscle cells in cocultured model2006
- Author(s)
  N.Sakamoto
- Journal Title
  
  Annals of Biomedical Engineering (in press)
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Effect of fluid shear stress on migration of vascular smooth muscle cells in cocultured model2006
- Author(s)
  N.Sakamoto
- Journal Title
  
  Annals of Biomedical Engineering (in press)
- Data Source
  KAKENHI-PROJECT-17200030
[Journal Article] 静水圧に対する培養内皮細胞の形態的変化とその評価方法2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第43回日本エム・イー学会大会プログラム・論文集 Vol.42 Suppl.1
  
  Pages: 589-589
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] 動脈硬化症発生メカニズムにおける内皮細胞と平滑筋細胞の相互作用2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第27回日本バイオレオロジー学会年会プログラム・抄録集 18
  
  Pages: 40-40
- NAID
  10012364336
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Effect of shear stress on permeability of vascular endothelial monolayer cocultured with smooth muscle cells2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  JSME Int J Ser C 47
  
  Pages: 992-999
- NAID
  110004820828
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] 静水圧に対する培養内皮細胞の形態的変化とその評価方法2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第43回日本エム・イー学会大会プログラム・論文集 Vol.42 Suppl.1
  
  Pages: 589-589
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Role of nitric oxide in migration of smooth muscle cells in cocultured model2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  The proceedings of The First Asian Pacific Conference on Biomechanics No.04-293
  
  Pages: 83-83
- Data Source
  KAKENHI-PROJECT-15650085
[Journal Article] 動脈硬化症発生メカニズムにおける内皮細胞と平滑筋細胞の相互作用2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第27回日本バイオレオロジー学会年会プログラム・抄録集 18巻
  
  Pages: 40-40
- NAID
  10012364336
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Role of nitric oxide in migration of smooth muscle cells in cocultured model2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  The proceedings of The First Asian Pacific Conference on Biomechanics No.04-293
  
  Pages: 83-83
- Data Source
  KAKENHI-PROJECT-14208100
[Journal Article] 静水圧に対する培養内皮細胞の形態的変化とその評価方法2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第43回日本エム・イー学会大会プログラム・論文集 Vol.42 Suppl.1
  
  Pages: 589-589
- Data Source
  KAKENHI-PROJECT-14208100
[Journal Article] Role of nitric oxide in migration of smooth muscle cells in cocultured model2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  Proc First Asia Pacific Conf Biomech 04-293
  
  Pages: 83-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Role of nitric oxide in migration of smooth muscle cells in cocultured model2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  The Proceedings of First Asia Pacific Conference on Biomechanics 04-293
  
  Pages: 83-84
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Effect of shear stress on permeability of vascular endothelial monolayer cocultured with smooth muscle cells.2004
- Author(s)
  N.Sakamoto, T.Ohashi, M.Sato
- Journal Title
  
  JSME Int.J.Ser.C 47(4)
  
  Pages: 992-999
- NAID
  110004820828
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208100
[Journal Article] 動脈硬化症発生メカニズムにおける内皮細胞と平滑筋細胞の相互作用2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第27回日本バイオレオロジー学会年会プログラム・抄録集 18巻
  
  Pages: 40-40
- NAID
  10012364336
- Data Source
  KAKENHI-PROJECT-15650085
[Journal Article] Evaluation of morphological change in cultured endothelial cells exposed to hydrostatic pressure (in Japanese)2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  43rd Ann Conf Jpn Soc Med Biol Eng Prog 42
  
  Pages: 589-589
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Effect of shear stress on permeability of vascular endothelial monolayer cocultured with smooth muscle cells2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  JSME International Journal Series C Vol.47, No.4
  
  Pages: 992-999
- NAID
  110004820828
- Data Source
  KAKENHI-PROJECT-14208100
[Journal Article] Effect of shear stress on permeability of vascular endothelial monolayer cocultured with smooth muscle cells2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  JSME International Journal Series C Vol.47,No.4
  
  Pages: 992-999
- NAID
  110004820828
- Data Source
  KAKENHI-PROJECT-15650085
[Journal Article] 共存培養モデルを用いた平滑筋細胞遊走性に与える一酸化窒素の影響2004
- Author(s)
  坂元尚哉
- Journal Title
  
  日本機械学会第16回バイオエンジニアリング講演会講演論文集 No.03-38
  
  Pages: 31-32
- Data Source
  KAKENHI-PROJECT-15650085
[Journal Article] Effect of shear stress on permeability of vascular endothelial monolayer cocultured with smooth muscle cells2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  JSME international Journal Series C Vol.47,No.4
  
  Pages: 992-999
- NAID
  110004820828
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] 共存培養モデルを用いた平滑筋細胞遊走性に与える一酸化窒素の影響2004
- Author(s)
  坂元尚哉
- Journal Title
  
  日本機械学会第16回バイオエンジニアリング講演会講演論文集 No.03-38
  
  Pages: 31-32
- Data Source
  KAKENHI-PROJECT-14208100
[Journal Article] 共存培養モデルを用いた平滑筋細胞遊走性に与える一酸化窒素の影響2004
- Author(s)
  坂元尚哉
- Journal Title
  
  日本機械学会第16回バイオエンジニアリング講演会講演論文集 No.03-38
  
  Pages: 31-32
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Role of nitric oxide in migration of smooth muscle cells in cocultured model2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  The proceedings of The First Asian Pacific Conference on Biomechanics No.04-293
  
  Pages: 83-83
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Role of nitric oxide in migration of smooth muscle cells in cocultured model2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  The proceedings of The First Asian Pacific Conference on Biomechanics No.04-293
  
  Pages: 83-83
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Effect of nitric oxide on migration of smooth muscle cells in cocultured model (in Japanese)2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  16th Bioeng Conf 2004 Ann Meeting of BED/JSME 03-38
  
  Pages: 31-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Role of cellular interaction between endothelial cells and smooth muscle cells in mechanism of atherogenesis (in Japanese)2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  27th J Jpn Soc Biorheol 18
  
  Pages: 40-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Effect of shear stress on permeability of vascular endothelial monolayer cocultured with smooth muscle cells2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  JSME Int.J. Ser.C 47(4)
  
  Pages: 992-999
- NAID
  110004820828
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208100
[Journal Article] 共存培養モデルを用いた平滑筋細胞遊走性に与える一酸化窒素の影響2004
- Author(s)
  坂元尚哉
- Journal Title
  
  日本機械学会第16回バイオエンジニアリング講演会講演論文集 No.03-38
  
  Pages: 31-32
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Effect of shear stress on permeability of vascular endothelial monolayer cocultured with smooth muscle cells2004
- Author(s)
  N. Sakamoto
- Journal Title
  
  JSME International Journal, Series C 47
  
  Pages: 992-999
- NAID
  110004820828
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15086203
[Journal Article] Effect of shear stress on permeability of vascular endothelial monolayer cocultured with smooth muscle cells2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  JSME International Journal Series C Vol.47,No.4
  
  Pages: 992-999
- NAID
  110004820828
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] 静水圧に対する培養内皮細胞の形態的変化とその評価2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第43回日本エム・イー学会大会プログラム・論文集 42
  
  Pages: 589-589
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] 共存培養モデルを用いた平滑筋細胞遊走性に与える一酸化窒素の影響2004
- Author(s)
  坂元尚哉
- Journal Title
  
  日本機械学会第16回バイオエンジニアリング講演会講演論文集 03-38
  
  Pages: 31-32
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Effect of shear stress on permeability of vascular endothelial monolayer cocultured with smooth muscle cells2004
- Author(s)
  N.Sakamoto
- Journal Title
  
  JSME International Journal Series C 47
  
  Pages: 992-999
- NAID
  110004820828
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] 動脈硬化症発生メカニズムにおける内皮細胞と平滑筋細胞の相互作用2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第27回日本バイオレオロジー学会年会プログラム・抄録集 18巻
  
  Pages: 40-40
- NAID
  10012364336
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] 静水圧に対する培養内皮細胞の形態的変化とその評価方法2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第43回日本エム・イー学会大会プログラム・論文集 Vol.42 Suppl.1
  
  Pages: 589-589
- Data Source
  KAKENHI-PROJECT-15650085
[Journal Article] 動脈硬化症発生メカニズムにおける内皮細胞と平滑筋細胞の相互作用2004
- Author(s)
  坂元尚哉
- Journal Title
  
  第27回日本バイオレオロジー学会年会プログラム・抄録集 18巻
  
  Pages: 40-40
- NAID
  10012364336
- Data Source
  KAKENHI-PROJECT-14208100
[Journal Article] せん断応力を負荷した共存培養血管モデルにおける平滑筋細胞遊走性の変化2003
- Author(s)
  坂元尚哉
- Journal Title
  
  第42回日本エム・イー学会大会論文集 41
  
  Pages: 391-391
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Fluid shear stress affects migration of smooth muscle cells cocultured with endothelial cells2003
- Author(s)
  N.Sakamoto
- Journal Title
  
  Proceedings of the 2003 Summer Bioengineering Conference (CD)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Fluid shear stress affects migration of vascular smooth muscle cells cocultured with endothelial cells2003
- Author(s)
  N.Sakamoto
- Journal Title
  
  Proc 2003 Summer Bioeng Conf (CD)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Changes in migration of smooth muscle cells in cocultured blood vessel model exposed to fluid shear stress (in Japanese)2003
- Author(s)
  N.Sakamoto
- Journal Title
  
  42nd Ann Conf Jpn Soc Med Biol Eng Prog 41
  
  Pages: 391-391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300153
[Journal Article] Effect of magnetic field on nitric oxide synthesis of cultured endothelial cells.2002
- Author(s)
  N.Sakamoto
- Journal Title
  
  International Journal Applied Electromagnetics and Mechanics 14
  
  Pages: 317-322
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208100
[Journal Article] Effect of magnetic field on nitric oxide synthesis of cultured endothelial cells2002
- Author(s)
  N.Sakamoto
- Journal Title
  
  International Journal Applied Electromagnetics and Mechanics 14
  
  Pages: 317-322
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208100
[Journal Article] Role of p120-Catenin in the Morphological Changes of Endothelial Cells Exposed to Fluid Shear Stress.
- Author(s)
  N.Sakamoto, K.Segawa, M.Kanzaki, T.Ohashi, M.Sato
- Journal Title
  
  Biochemical and Biophysical Research Communications Vol.398
  
  Pages: 426-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] 壁せん断応力下の血管平滑筋細胞の形態応答における内皮細胞間との相互作用2024
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、山﨑雅史、藤江裕道、坂元尚哉．
- Organizer
  第63回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 内皮細胞間との相互作用による血管平滑筋細胞への力学環境情報伝達．2024
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、山﨑雅史、藤江裕道、坂元尚哉
- Organizer
  日本機械学会2024年度年次大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] Interaction with endothelial cells induces vascular smooth muscle cell orientation under wall shear stress condition.2024
- Author(s)
  Sawasaki K, Nakamura M, Kimura N, Kawahito K, Yamazaki M, Fujie H, Sakamoto N.
- Organizer
  Biomechanics, Bioengineering and Biotransport Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力に対する血管内皮細胞内アクチンフィラメント構造の変化.2024
- Author(s)
  山﨑瑠海, 髙橋幸慈, 沢崎薫, 中村匡徳, 木村直行, 川人宏次, 坂元尚哉.
- Organizer
  第36回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 特異的血流環境を模擬した高壁せん断応力が血管モデル内平滑筋細胞の表現型転換へ及ぼす影響の評価2023
- Author(s)
  沢崎薫，中村匡徳，木村直行, 川人宏次，藤江裕道，坂元尚哉
- Organizer
  第65回日本平滑筋学会総会 (東京, 2023年8月4-5日)
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] 特異的血流環境を模擬した高壁せん断応力が血管モデル内平滑筋細胞の表現型転換へ及ぼす影響の評価2023
- Author(s)
  沢崎薫，中村匡徳，木村直行，川人宏次，藤江裕道，坂元尚哉
- Organizer
  第65回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-22K19898
[Presentation] Phenotypic States of Smooth Muscle Cells in a Coculture Model under Higher Wall Shear Stress Condition2023
- Author(s)
  K. Sawasaki, M. Nakamura, N. Kimura, K. Kawahito, H. Fujie, N. Sakamoto
- Organizer
  2022 Biomedical Engineering Society Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19898
[Presentation] Vascular Smooth Muscle Cell Alignment Induced by Cocultured Endothelial Cells Subjected to Wall Shear Stress2023
- Author(s)
  K. Sawasaki, M. Nakamura, N. Kimura, K. Kawahito, H. Fujie, N. Sakamoto
- Organizer
  2023 BMES Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19898
[Presentation] コラーゲンゲル基質弾性率が脳血管内皮細胞の細胞間接着形成に与える影響2023
- Author(s)
  髙橋幸慈，山﨑雅史，藤江裕道，坂元尚哉
- Organizer
  日本機械学会第34回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-22K19898
[Presentation] 壁せん断応力環境下における内皮細胞と共培養した血管平滑筋細胞の形態変化2023
- Author(s)
  沢崎薫，中村匡徳，木村直行，川人宏次，藤江裕道，坂元尚哉
- Organizer
  第62回日本生体医工学会年会
- Data Source
  KAKENHI-PROJECT-22K19898
[Presentation] Vascular Smooth Muscle Cell Orientation Induced by Cocultured Endothelial Cells Subjected to Wall Shear Stress2023
- Author(s)
  Kaoru Sawasaki, Masanori Nakamura, Naoyuki Kimura, Koji Kawahito, Hiromichi Fujie, Naoya Sakamoto.
- Organizer
  2023 BMES Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力に対する内皮細胞を介した血管平滑筋細胞の形態変化．2023
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉．壁せん断応力に対する内皮細胞を介した血管平滑筋細胞の形態変化．
- Organizer
  日本機械学会2023年度年次大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力環境下における内皮細胞と共培養した血管平滑筋細胞の形態変化2023
- Author(s)
  5.沢崎薫，中村匡徳，木村直行，川人宏次，藤江裕道，坂元尚哉
- Organizer
  第62回日本生体医工学会大会 (名古屋, 2023年5月18-20日)
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] 壁せん断応力に対する内皮細胞を介した血管平滑筋細胞の形態変化2023
- Author(s)
  沢崎薫，中村匡徳，木村直行，川人宏次，藤江裕道，坂元尚哉
- Organizer
  日本機械学会2022年度年次大会
- Data Source
  KAKENHI-PROJECT-22K19898
[Presentation] 血管内皮細胞によるNO産生と衝突噴流環境との関係．2023
- Author(s)
  沢崎薫、山﨑瑠海、髙橋幸慈、中村匡徳、木村直行、川人宏次、坂元尚哉．
- Organizer
  第46回バイオレオロジー学会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力に対する内皮細胞を介した血管平滑筋細胞の形態変化2023
- Author(s)
  沢崎薫，中村匡徳，木村直行，川人宏次，藤江裕道，坂元尚哉
- Organizer
  日本機械学会2023年度年次大会 (東京, 2023年9月3－6日)
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] 壁せん断応力環境下における内皮細胞と共培養した血管平滑筋細胞の形態変化．2023
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉．
- Organizer
  第62回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 高壁せん断応力下における血管内皮細胞と共培養した血管平滑筋細胞の表現型転換2022
- Author(s)
  沢崎薫，中村匡徳，木村直行，川人宏次，藤江裕道，坂元尚哉
- Organizer
  日本機械学会2022年度年次大会
- Data Source
  KAKENHI-PROJECT-22K19898
[Presentation] Study on Effect of Extreme Shear Condition on Endothelial Cell and Smooth muscle Cell Functions using Compressed Collagen Construct.2022
- Author(s)
  1．Sakamoto N, Oyama Y, Sawasaki K, Hiroshima Y, Nakamura M, Kimura N, Kawahito K, Fujie H
- Organizer
  9th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力-法線方向動圧組み合わせ環境が血管内皮細胞に及ぼす影響．2022
- Author(s)
  髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉．
- Organizer
  第45回日本バイオレオロジー学会年会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] Phenotypic States of Smooth Muscle Cells in a Coculture Model under Higher Wall Shear Stress Condition2022
- Author(s)
  Sawasaki K, Nakamura M, Kimura N, Kawahito K, Fujie H, Sakamoto N
- Organizer
  2022 BMES Annual Meeting
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 高壁せん断応力が内皮細胞と共培養した血管平滑筋細胞の表現型へ及ぼす影響2022
- Author(s)
  沢崎薫，中村匡徳，木村直行，川人宏次，藤江裕道，坂元尚哉
- Organizer
  第61回日本生体医工学会年会
- Data Source
  KAKENHI-PROJECT-22K19898
[Presentation] 衝突噴流に伴う力学刺激の組み合わせ環境が血管内皮細胞に及ぼす影響2022
- Author(s)
  髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉
- Organizer
  第32回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 高壁せん断応力が内皮細胞と共培養した血管平滑筋細胞の表現型へ及ぼす影響2022
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉
- Organizer
  第61回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 高壁せん断応力を負荷した共培養血管モデルにおける平滑筋細胞の表現型2022
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉
- Organizer
  日本機械学会 2022年度年次大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] Study on Effect of Extreme Shear Condition on Endothelial Cell and Smooth muscle Cell Functions using Compressed Collagen Construct2022
- Author(s)
  Sakamoto N, Oyama Y, Sawasaki K, Hiroshima Y, Nakamura M, Kimura N, Kawahito K, Fujie H.
- Organizer
  9th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 衝突噴流が血管内皮細胞間接着に及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，川人宏次，坂元尚哉
- Organizer
  日本機械学会第33回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 内皮-平滑筋細胞共培養モデルのMMP産生に対する高壁せん断応力環境の影響2020
- Author(s)
  坂元尚哉，大山侑樹，中村匡徳，木村直行，川人宏次，山崎雅史，藤江裕道
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 高浸透圧刺激による尿細管細胞の細胞骨格構造の変化が腎線維化に与える影響2020
- Author(s)
  宮野貴士，鈴木敦詞，坂元尚哉
- Organizer
  第59回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Effects of the hyperosmolarity-induced cytoskeletal changes of tubule epithelial cells on renal fibrosis2020
- Author(s)
  T. Miyano, A. Suzuki, N. Sakamoto
- Organizer
  TMU International Symposium: Multi-scale biomechanics, nano-to macro-scale
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Intranuclear mechanics under cell substrate stretching: AN experimental and computational study2020
- Author(s)
  S. Tsukamoto, S. Kimura, T. Asakawa, N. Takesue, M.R.K. Mofrad, N. Sakamoto
- Organizer
  Intranuclear mechanics under cell substrate stretching: AN experimental and computational study
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] ヒト間葉系幹細胞の細胞核内粘弾性変化の骨芽細胞分化における役割2020
- Author(s)
  松下晃次郎，坂元尚哉，伊井仁志，三好洋美
- Organizer
  日本機械学会2020年度年次大会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Effects of the hyperosmolarity-induced cytoskeletal changes of tubule epithelial cells on renal fibrosis2020
- Author(s)
  T. Miyano, A. Suzuki, N. Sakamoto
- Organizer
  TMU International Symposium: Multi-scale biomechanics, nano-to macro-scale
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] 高浸透圧条件下における尿細管細胞内カルシウムイオン濃度変化2020
- Author(s)
  鈴木敦詞，宮野貴士，坂元尚哉
- Organizer
  日本機械学会第31回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Quantitative analysis of nuclear local viscoelastic changes in human Mesenchymal Stem Cells during osteoblast differentiation2020
- Author(s)
  K. Matsushita, N. Sakamoto, S. Ii, H. Miyoshi
- Organizer
  Summer Biomechanics, Bioengineering and Biotransport Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，　川人宏次，坂元尚哉
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 細胞核変形の細胞外基質伸展方向との関係2020
- Author(s)
  塚本真悟，Keng-Hwee Chaim，武居直行，坂元尚哉
- Organizer
  日本機械学会第31回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Heterogeneous strain distribution within the nucleus under substrate stretching is caused by chromatin condensation2019
- Author(s)
  S. Tukamoto, S. Kimura, N. Takesue, N. Sakamoto
- Organizer
  2019 BMES Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] 接着基質力学特性の違いによって引き起こされる細胞内張力の変化2019
- Author(s)
  伊藤佳祐，伊井仁志，Daniel　Conway，坂元尚哉
- Organizer
  日本機械学会第32回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Roles of nuclear membrane proteins in cyclic stretch-induced changes of nuclear elasticity of fibroblasts2019
- Author(s)
  N. Sakamoto, K. Kashima, M. Takeuchi, N. Kataoka
- Organizer
  2019 BMES Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] Heterogeneous strain distribution within the nucleus under substrate stretching is caused by chromatin condensation2019
- Author(s)
  S. Tukamoto, S. Kimura, N. Takesue, N. Sakamoto
- Organizer
  2019 BMES Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Heterogeneous strain distribution within the nucleus under substrate stretching is caused by chromatin condensation2019
- Author(s)
  S. Tukamoto, S. Kimura, N. Takesue, N. Sakamoto
- Organizer
  2019 BMES Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02077
[Presentation] 接着基質力学特性の違いによって引き起こされる細胞内張力の変化2019
- Author(s)
  伊藤佳祐，伊井仁志，Daniel　Conway，坂元尚哉
- Organizer
  日本機械学会第32回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] ヒト間葉系幹細胞の骨分化過程における細胞核内局所粘弾性の定量評価2019
- Author(s)
  松下晃次郎，坂元尚哉，伊井仁志，三好洋美
- Organizer
  日本機械学会2019年度年次大会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Inverse Estimation of 3-D Traction Stress Field of Adhered Cell based on Optimal Control Technique using Image Intensities2019
- Author(s)
  S. Ii, K. Ito, N. Takakusaki, N. Sakamoto
- Organizer
  International Conference on Biomehanics and Medical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Inverse Estimation of 3-D Traction Stress Field of Adhered Cell based on Optimal Control Technique using Image Intensities2019
- Author(s)
  S. Ii, K. Ito, N. Takakusaki, N. Sakamoto
- Organizer
  International Conference on Biomehanics and Medical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02077
[Presentation] 接着基質力学特性の違いによって引き起こされる細胞内張力の変化2019
- Author(s)
  伊藤佳祐，伊井仁志，Daniel　Conway，坂元尚哉
- Organizer
  日本機械学会第32回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-17H02077
[Presentation] 間葉系幹細胞の内皮細胞分化効率向上を目指した組合せ力学環境の検討2019
- Author(s)
  舘林耕平　三好洋美　山崎雅史　坂元尚哉
- Organizer
  日本機械学会第32回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Condensation Level of Chromatin Affects Local Strain within the Nucleus under Mechanical Stimuli2019
- Author(s)
  S. Tsukamoto, S., Kimura, N. Takesue, N. Sakamoto
- Organizer
  3rd International Symposium on Nanoarchitectonics for Mechanobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] Roles of nuclear membrane proteins in cyclic stretch-induced changes of nuclear elasticity of fibroblasts2019
- Author(s)
  N. Sakamoto, K. Kashima, M. Takeuchi, N. Kataoka
- Organizer
  2019 BMES Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Condensation Level of Chromatin Affects Local Strain within the Nucleus under Mechanical Stimuli2019
- Author(s)
  S. Tsukamoto, S., Kimura, N. Takesue, N. Sakamoto
- Organizer
  3rd International Symposium on Nanoarchitectonics for Mechanobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] 圧縮コラーゲン組織を用いた共培養モデルに対する高壁せん断応力の影響2019
- Author(s)
  大山侑樹，中村匡徳，木村直行，川人宏次，山崎雅史，藤江裕道，坂元尚哉
- Organizer
  日本機械学会第32回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] Inverse Estimation of 3-D Traction Stress Field of Adhered Cell based on Optimal Control Technique using Image Intensities2019
- Author(s)
  S. Ii, K. Ito, N. Takakusaki, N. Sakamoto
- Organizer
  International Conference on Biomehanics and Medical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] パーティクルトラッキング法による細胞核内局所力学特性の評価2018
- Author(s)
  木村　俊，三好　洋美，伊井　仁志，坂元　尚哉
- Organizer
  日本機械学会第29回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] 超高壁せん断応力による血管内皮細胞のMMPおよびeNOS産生の変化2018
- Author(s)
  大山侑樹，中村匡徳，木村直行，坂元尚哉
- Organizer
  日本機械学会2018年度年次大会
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] Mechanical conditions of nesprin-mediated nucleus-actin filament bindings affect polarized elongation of fibroblasts induced by cyclic stretching2018
- Author(s)
  N. Sakamoto, M. Ogawa, K. Sadamoto, M. Takeuchi, N. Kataoka
- Organizer
  8th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] Matrix metalloproteinase production of vascular endothelial cells under extremely high wall shear stress condition. The International Society of Biorheology2018
- Author(s)
  N. Sakamoto, Y. Oyama, Y. Horie, M. Nakamura, N. Kimura
- Organizer
  The International Society of Biorheology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] 繰り返し伸展刺激による繊維芽細胞核の弾性特性変化における核膜タンパク質の役割2018
- Author(s)
  香嶋　謙志郎，竹内　雅貴，片岡　則之，坂元　尚哉
- Organizer
  日本機械学会第31回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-18K19934
[Presentation] Mechanical conditions of nesprin-mediated nucleus-actin filament bindings affect polarized elongation of fibroblasts induced by cyclic stretching2018
- Author(s)
  N. Sakamoto, M. Ogawa, K. Sadamoto, M. Takeuchi, N. Kataoka
- Organizer
  8th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] 繰り返し伸展刺激による繊維芽細胞核の弾性特性変化における核膜タンパク質の役割2018
- Author(s)
  香嶋　謙志郎，竹内　雅貴，片岡　則之，坂元　尚哉
- Organizer
  日本機械学会第31回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] パーティクルトラッキング法による細胞核内局所力学特性の評価2018
- Author(s)
  木村　俊，三好　洋美，伊井　仁志，坂元　尚哉
- Organizer
  日本機械学会第29回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] 接着基質伸展に伴う細胞内局所変形挙動のその場観察装置の開発2018
- Author(s)
  小林裕季，木村　俊，武居直行，坂元尚哉
- Organizer
  日本機械学会関東学生会第57回学生員卒業研究発表講演会
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] UTILITY OF COMPUTATIONAL FLUID DYNAMICS FOR THORACIC AORTIC PATHOLOGY IN THE ERA OF PRECISION MEDICINE2018
- Author(s)
  NAOYUKI KIMURA, KOJI KAWAHITO, DAIJIRO HORI, KOICHI YURI, ATSUSHI YAMAGUCHI, YUUKI OHYAMA, NAOYA SAKAMOTO, MASANORI NAKAMURA
- Organizer
  第83回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] 血管内皮細胞の遊走および剥離に対する衝突流れ場の影響2018
- Author(s)
  堀江悠太，大山侑樹，中村匡徳，木村直行，川人宏次，坂元尚哉
- Organizer
  日本機械学会第31回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-18H03521
[Presentation] 線維芽細胞牽引力に対する細胞核の力学的役割2017
- Author(s)
  伊藤佳祐，伊井仁志，和田成生，坂元尚哉
- Organizer
  日本機械学会第28回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] 高せん断応力環境に対する血管内皮細胞の形態応答2017
- Author(s)
  坂元尚哉，堀江悠太，大山侑樹，舘林耕平，中村匡徳
- Organizer
  第40回日本バイオレオロジー学会年会
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] 伸展刺激による線維芽細胞核力学特性変化に対するNesprinを介した力学伝達の寄与2017
- Author(s)
  坂元尚哉，香嶋謙志郎，定本紀代美，小川麻衣，片岡則之，竹内雅貴
- Organizer
  日本機械学会
- Data Source
  KAKENHI-PROJECT-16K15837
[Presentation] 繰り返し伸展刺激による細胞形態変化と細胞核力学特性の関係2017
- Author(s)
  坂元尚哉，定本紀代美，小川麻衣，片岡則之，竹内雅貴
- Organizer
  日本機械学会第29回バイオエンジニアリング講演会
- Place of Presentation
  ウインクあいち（愛知県名古屋市）
- Year and Date
  2017-01-20
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] 細胞核-アクチンフィラメント結合が伸展刺激による細胞核力学特性変化に果たす役割2017
- Author(s)
  坂元尚哉，定本紀代美，小川麻衣，片岡則之，竹内雅貴
- Organizer
  第37回バイオトライボロジシンポジウム
- Place of Presentation
  首都大学東京秋葉原キャンパス（東京都千代田区）
- Year and Date
  2017-03-11
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] 伸展刺激による線維芽細胞核力学特性変化に対するNesprinを介した力学伝達の寄与2017
- Author(s)
  坂元尚哉，香嶋謙志郎，定本紀代美，小川麻衣，片岡則之，竹内雅貴
- Organizer
  日本機械学会第30回バイオエンジにリング講演会
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] 細胞核 - アクチンフィラメント結合が伸展刺激による細胞核力学特性変化に果たす役割2017
- Author(s)
  坂元尚哉，定本紀代美，小川麻衣，片岡則之，竹内雅貴，香嶋謙志郎
- Organizer
  バイオトライボロジ学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15837
[Presentation] 繰り返し伸展刺激を負荷した線維芽細胞核の弾性率に対するNesprin-1発現抑制の影響2016
- Author(s)
  定本紀代美，小川麻衣，片岡則之，竹内雅貴，坂元尚哉
- Organizer
  日本機械学会第28回バイオエンジニアリング講演会
- Place of Presentation
  東京
- Year and Date
  2016-01-09
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] Changes in Nuclear Stiffness of Nesprin-1 Depleted Fibroblasts Exposed to Cyclic Stretching2016
- Author(s)
  N. Sakamoto, K. Sadamoto, M. Ogawa, M. Takeuchi, N. Kataoka
- Organizer
  Summer Biomechanics, Bioengineering and Biotransport Conference
- Place of Presentation
  Maryland (USA)
- Year and Date
  2016-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] 細胞の力学応答における細胞核の構造的・力学的役割の検討2016
- Author(s)
  坂元尚哉
- Organizer
  第17回流体科学におけるバイオ・医療に関する研究会
- Place of Presentation
  仙台
- Year and Date
  2016-02-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] 細胞核ーアクチンフィラメント結合を阻害した細胞の力学応答2015
- Author(s)
  坂元尚哉
- Organizer
  イノバイオ研究会
- Place of Presentation
  東京
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] Proliferation of Nesprin-1 Knocked-down Fibroblasts Cultured on Substrates of Different Stiffness2015
- Author(s)
  N. Sakamoto, T. Kishimoto, C.E. Kuriki
- Organizer
  International Conference on Advanced Technology in Experimental Mechanics 2015
- Place of Presentation
  Toyohashi, Japan
- Year and Date
  2015-10-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] Nesprin-1を発現抑制した線維芽細胞の繰り返し伸展刺激に対する形態変化2015
- Author(s)
  坂元尚哉，小川麻衣，定本紀代美
- Organizer
  第54回日本生体医工学会大会
- Place of Presentation
  名古屋
- Year and Date
  2015-05-08
- Data Source
  KAKENHI-PROJECT-15K01304
[Presentation] 原子間力顕微鏡を用いた細胞核-アクチンフィラメント結合の評価2013
- Author(s)
  中鉢辰也,阿武俊郎,坂元尚哉,出口真次,佐藤正明
- Organizer
  日本機械学会第25回バイオエンジニアリング講演会
- Place of Presentation
  つくば
- Year and Date
  2013-01-10
- Data Source
  KAKENHI-PROJECT-23650250
[Presentation] Identification of Rho-GEFs involved in mechano-biological responses of vascular endothelial cells2013
- Author(s)
  Ohashi K., Abiko H., Kondo H., Fujiwara S., Mashiko K., Sakamoto N., Sato M., Mizuno K.
- Organizer
  International Symposium on Biomedical Engineering Interface
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22616001
[Presentation] Role of Nucleus-Actin Filament Binding in Endothelial Cell Responses to Cyclic Stretching2013
- Author(s)
  N. Sakamoto, T. Anno, S. Chubachi, S.Deguchi, M. Sato
- Organizer
  International Symposium on Bio Medical Engineering Interface
- Place of Presentation
  仙台
- Year and Date
  2013-03-15
- Data Source
  KAKENHI-PROJECT-23650250
[Presentation] 内皮細胞における細胞核とアクチンフィラメント結合の生体力学的検討2013
- Author(s)
  坂元尚哉,阿武俊郎,中鉢辰也,出口真次,佐藤正明
- Organizer
  日本生体医工学会専門別研究会バイオメカニクス研究会146回研究会
- Place of Presentation
  徳島
- Year and Date
  2013-01-25
- Data Source
  KAKENHI-PROJECT-23650250
[Presentation] Identification of Rho-GEFs Involved in Cyclic Stretch-induced Mechanosensing of Vascular Endothelial Cells2012
- Author(s)
  Kondo, H., Ohashi, K., Abiko, H., Hiatari, R., Sakamoto, N., Sato, M., Mizuno, K.
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22616001
[Presentation] 細胞核ー細胞骨格結合が内皮細胞の力学応答に果たす役割2012
- Author(s)
  中鉢辰也,阿武俊郎,坂元尚哉,出口真次,佐藤正明
- Organizer
  第46回日本生体医工学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-23650250
[Presentation] Morphological response of vascular endothelial cells to spatial gradient of fluid shear stress2012
- Author(s)
  N.Sakamoto
- Organizer
  International Symposium on Cellular Mechanobiology
- Place of Presentation
  京都大学(京都市)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Vascular endothelial cell morphology exposed to fluid shear stress with spacial gradient2012
- Author(s)
  N. Sakamoto
- Organizer
  World Cong. Med. Phys. Biomed. Eng.
- Place of Presentation
  Beijin (China)
- Year and Date
  2012-05-28
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Identification of Rho-GEFs involved in mechanosensing of vascular endothelial cells2012
- Author(s)
  Kondo, H., Ohashi, K., Abiko, H., Hiatari, R., Sakamoto, N., Sato, M., Mizuno, K.
- Organizer
  第45回日本発生生物学会・第64回日本細胞生物学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22616001
[Presentation] MAPキナーゼを介した空間的せん断応力勾配に対する内皮細胞の形態応答2012
- Author(s)
  坂元尚哉
- Organizer
  第24回バイオエンジニアリング講演会
- Place of Presentation
  大阪大学(豊中市)
- Year and Date
  2012-01-08
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Mechanical Role of Nesprin-1 in Nuclear Shape in Vascular Endothelial Cells Subjected to Stretching2012
- Author(s)
  N. Sakamoto, T. Anno, M. Sato
- Organizer
  Biomedical Engineering Society2012 Annual Meeting
- Place of Presentation
  Atlanta (USA)
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-23650250
[Presentation] 空間的せん断応力勾配負荷による内皮細胞間接着部のチロシンリン酸化2011
- Author(s)
  坂元尚哉
- Organizer
  第50回日本生体医工学会大会
- Place of Presentation
  東京電機大学(東京都)
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Response of vascular endothelial cells to spatial gradient of fluid shear stress2011
- Author(s)
  N.Sakamoto
- Organizer
  1st Annual World Congress of Molecular and Cell Biology
- Place of Presentation
  北京(中国)(招待講演)
- Year and Date
  2011-08-07
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Identification ofRho-GEFs that are involved in mechanotransduction of vascular endothelial cells2011
- Author(s)
  Ohashi, K., Abiko, H., Tsuji, T., Naotsuka, M., Hiatari, R., Sakamoto, N., Sato, M., Mizuno, K.
- Organizer
  The 6th International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease
- Place of Presentation
  Rotterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-22616001
[Presentation] メカノストレス応答に関わるRho-GEFの網羅的探索2010
- Author(s)
  安彦日和、辻拓史、直塚萌、大橋一正、坂元尚哉、佐藤正明、水野健作
- Organizer
  日本分子生物学会第10回春季シンポジウム
- Place of Presentation
  松島
- Data Source
  KAKENHI-PROJECT-22616001
[Presentation] Spatial Gradient of Shear Stress Induces Phosphorylation of Cell-Cell Adhesion Proteins in Endothelial Cells2010
- Author(s)
  N.Sakamoto
- Organizer
  KIST-Tohoku Joint Symposium on Nanobiomedical Engineering
- Place of Presentation
  ソウル,韓国
- Year and Date
  2010-08-30
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Spatial gradient of shear stress induces phosphorylation of cell-cell adhesion proteins in endothelial cells2010
- Author(s)
  N.Sakamoto
- Organizer
  KIST-Tohoku Joint Symposium on Nanobiomedical Engineering
- Place of Presentation
  ソウル(韓国)
- Year and Date
  2010-08-30
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Tyrosine phosphorylation of endothelial cell-cell adhesion proteins induced by shear stress gradient2010
- Author(s)
  N.Sakamoto
- Organizer
  BMES Annual Meeting 2010
- Place of Presentation
  オースチン(米国)
- Year and Date
  2010-10-06
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Effect of cyclic stretch on production of inflammatory cytokines from macrophages2010
- Author(s)
  N.Sakamoto
- Organizer
  The 6th World Congress on Biomechanics
- Place of Presentation
  シンガポール
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Effect of spatial gradient of shear stress on morphological responses of endothelial cells to flow2010
- Author(s)
  N.Sakamoto
- Organizer
  6th World Congress on Biomechanics
- Place of Presentation
  サンテックシンガポール国際会議展示場(シンガポール)
- Year and Date
  2010-08-01
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Tyrosine phosphorylation of endothelial cell-cell adhesion proteins induced by shear stress gradient.2010
- Author(s)
  N.Sakamoto
- Organizer
  BMES Annual Meeting 2010
- Place of Presentation
  オースティン,米国
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Effect of Spatial Gradient of Shear Stress on Morphological Responses of Endothelial Cells to Flow2010
- Author(s)
  N.Sakamoto
- Organizer
  Nano-Biomedical Engineering in the East Asian-Pacific Rim Region
- Place of Presentation
  シンガポール,シンガポール
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Morphological changes in vascular endothelial cells exposed to spatial gradient of shear stress2010
- Author(s)
  Sakamoto, N
- Organizer
  MIT-NUS-NTU-Tohoku University Global COE Joint Workshop on Micro & Nano Bioengineering
- Place of Presentation
  シンガポール, シンガポール国立大学
- Year and Date
  2010-01-12
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Effect of cyclic stretch on production of inflammatory cytokines from macrophages2010
- Author(s)
  N.Sakamoto
- Organizer
  6th World Congress on Biomechanics
- Place of Presentation
  サンテックシンガポール国際会議展示場(シンガポール)
- Year and Date
  2010-08-01
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Effect of spatial gradient of shear stress on morphological responses of endothelial cells to flow.2010
- Author(s)
  N.Sakamoto
- Organizer
  Nano-Biomedical Engineering in the East Asian-Pacific Rim Region
- Place of Presentation
  シンガポール,シンガポール
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Tyrosine Phosphorylation of Endothelial Cell-Cell Adhesion Proteins Induced by Shear Stress Gradient2010
- Author(s)
  N.Sakamoto
- Organizer
  BMES Annual Meeting 2010
- Place of Presentation
  オースティン,米国
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Effect of cyclic stretch on production of inflammatory cytokines from macrophages2010
- Author(s)
  N.Sakamoto
- Organizer
  The 6th World Congress on Biomechanics
- Place of Presentation
  シンガポール,シンガポール
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Spatial gradient of shear stress induces phosphorylation of cell-cell adhesion proteins in endothelial cells.2010
- Author(s)
  N.Sakamoto
- Organizer
  KIST-Tohoku Joint Symposium on Nanobiomedical Engineering
- Place of Presentation
  ソウル,韓国
- Year and Date
  2010-08-30
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Identification of Rho-GEFs involved in mechnotranduction of vascular endothelial cell2010
- Author(s)
  Abiko, H., Tsuji, T., Naotsuka, M., Hiatari, R., Sakamoto, N., Sato, M., Ohashi, K., Mizuno, K.
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22616001
[Presentation] Morphological changes in vascular endothelial cells exposed to spatial gradient of shear stress.2010
- Author(s)
  N.Sakamoto
- Organizer
  MIT-NUS-NTU-Tohoku University Global COE Joint Workshop on Micro & Nano Bioengineering
- Place of Presentation
  シンガポール,シンガポール
- Year and Date
  2010-01-12
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Morphological changes in cultured endothelial cells exposed to high shear stress and high shear stress gradient.2009
- Author(s)
  N.Sakamoto
- Organizer
  BMES 2009 Annual Fall Scientific Meeting
- Place of Presentation
  ピッツバーグ,米国
- Year and Date
  2009-10-08
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Morphological changes in cultured endothelial cells exposed to high shear stress and high shear stress gradient2009
- Author(s)
  Sakamoto, N
- Organizer
  BMES 2009 Annual Fall Scientific Meeting
- Place of Presentation
  米国, ピッツバーグ
- Year and Date
  2009-10-08
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Production of matrix metalloproteinases of endothelial cells under high shear stress condition.2009
- Author(s)
  N.Sakamoto
- Organizer
  6th International Intracranial Stent Meeting
- Place of Presentation
  仙台
- Year and Date
  2009-08-06
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Production of matrix metalloproteinases of endothelial cells under high shear stress condition2009
- Author(s)
  Sakamoto, N
- Organizer
  6th International Intracranial Stent Meeting
- Place of Presentation
  仙台, 戦災復興記念館
- Year and Date
  2009-08-06
- Data Source
  KAKENHI-PROJECT-21700457
[Presentation] Influence of fluid shear stress on matrix metalloproteinase production in endothelial cells2008
- Author(s)
  Naoya Sakamoto
- Organizer
  13th International Conference on BioMedical Engineering
- Place of Presentation
  シンガポール
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-20001007
[Presentation] Transendothelial migration of leukocytes in cocultured vessel model exposed to shear stress2006
- Author(s)
  N. Sakamoto
- Organizer
  Annual Fall Meeting of BMES
- Place of Presentation
  Illinois, USA
- Year and Date
  2006-10-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15086203
[Presentation] Transendothelial migration of leukocytes in cocultured vessel model exposed to shear stress2006
- Author(s)
  Naoya Sakamoto
- Organizer
  2006 Annual Fall Meeting of BMES
- Place of Presentation
  イリノイ(アメリカ)
- Year and Date
  2006-10-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15086203
[Presentation] 静水圧に対する培養内皮細胞の形態的変化とその評価方法2004
- Author(s)
  坂元尚哉
- Organizer
  第43回日本エム・イー学会大会
- Place of Presentation
  石川
- Year and Date
  2004-05-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15086203
[Presentation] Evaluation of morphological change in cultured endothelial cells exposed to hydrostatic pressure(In Japanese)2004
- Author(s)
  N. Sakamoto
- Organizer
  The 43rd Annual Conference of Japanese Society for Medical and Biological Engineering
- Place of Presentation
  Ishikawa, Japan
- Year and Date
  2004-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15086203
[Presentation] Endothelial cells exposed to fluid shear stress regulate migration of cocultured smooth muscle cells2003
- Author(s)
  N. Sakamoto
- Organizer
  2003 Summer Bioengineering Congress
- Place of Presentation
  Florida, USA
- Year and Date
  2003-06-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15086203
[Presentation] Endothelial cells exposed to fluid shear stress regulate migration of cocultured smooth muscle cells2003
- Author(s)
  Naoya Sakamoto
- Organizer
  2003 Summer Bioengineering Congress
- Place of Presentation
  フロリダ(アメリカ)
- Year and Date
  2003-06-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15086203
[Presentation] Mechanical Role of Nesprin-1 in Nuclear Shape in Vascular Endothelial Cells Subjected to Stretching
- Author(s)
  N. Sakamoto
- Organizer
  Biomedical Engineering Society 2012 Annual Meeting
- Place of Presentation
  Georgia World Congress Center（米国）
- Data Source
  KAKENHI-PROJECT-23650250
[Presentation] Role of Nucleus-Actin Filament Binding in Endothelial Cell Responses to Cyclic Stretching
- Author(s)
  N. Sakamoto
- Organizer
  International Symposium on Bio Medical Engineering Interface
- Place of Presentation
  東北大学（宮城県）
- Invited
- Data Source
  KAKENHI-PROJECT-23650250
[Presentation] 内皮細胞における細胞核とアクチンフィラメント結合の生体力学的検討
- Author(s)
  坂元尚哉
- Organizer
  日本生体医工学会専門別研究会バイオメカニクス研究会146回研究会
- Place of Presentation
  徳島大学（徳島県）
- Data Source
  KAKENHI-PROJECT-23650250

1. SATO Masaaki (30111371)

# of Collaborated Projects: 12 results

# of Collaborated Products: 8 results
2. OHASHI Toshiro (30270812)

# of Collaborated Projects: 12 results

# of Collaborated Products: 4 results
3. DEGUCHI Shinji (30379713)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
4. Kimura Naoyuki (20382898)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
5. 中村匡徳 (20448046)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
6. ADACHI Taiji (40243323)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OHASHI Kazumasa (10312539)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. Kawahito Koji (90281740)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
9. 相澤啓 (50398517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. KANNZAKI Makoto (10272262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. OGURA Toshihiko (60273851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MAEDA Eijiro (20581614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HANE Kazuhiro (50164893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MATSUMOTO Takao (30209639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAMIOKA HIROSHI (80253219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Nagayama Kazuaki (10359763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 早野暁 (20633712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 菅原路子 (30323041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 伊藤智 (30382881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 田中正史 (80382927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 三好洋美 (50455367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
22. 伊井仁志 (50513016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
23. 岡村誉 (70438646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 藤江裕道 (20199300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
25. 中西真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakamoto Naoya 坂元 尚哉

SAKAMOTO NAOYA 坂元 尚哉

SAKAMOTO Naoya 坂元 尚哉

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Elucidation of high gravity-sensing mechanisms in cells and its application to control cellular phenotype and differentiationPrincipal Investigator

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Verification of local translational mechanism contributing to polarized cellular mechano-responsesPrincipal Investigator

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Study on the role of the mechanical dynamics in the nucleus in cellular mechanical responsesPrincipal Investigator

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Study of the role of nuclear mechanical remodeling in cellular mechano-responsesPrincipal Investigator

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STUDY ON ROLE OF INTRACELLULAR FORCE TRANSMISSION VIA LINC COMPLEX IN CELL RESPONSESPrincipal Investigator

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Fundamental Study for Development of An Engineering Model of Remodeling Mechanism of Blood Vessel Walls in Response to Mechanical EnvironmentPrincipal Investigator

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Sakamoto Naoya 坂元尚哉

SAKAMOTO NAOYA 坂元尚哉

SAKAMOTO Naoya 坂元尚哉