Kobayashi Seimi 小林成美

… Alternative Names

Satomi-Kobayashi Seimi 小林成美

小林成美コバヤシセイミ

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Researcher Number	20379415
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 特命教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 神戸大学, 医学部附属病院, 特命准教授 2018: 神戸大学, 医学部附属病院, 特命講師 2017: 神戸大学, 医学研究科, 特命講師 2016: 神戸大学, 医学部附属病院, 助教 2006 – 2007: 神戸大学, 医学系研究科, 医学研究員
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Applied health science / Circulatory organs internal medicine Except Principal Investigator Basic Section 58010:Medical management and medical sociology-related
Keywords	Principal Investigator 心不全 / 心臓線維化 / denovo脂肪酸合成 / 心臓リモデリング / グルタミン代謝 / 心筋代謝リモデリング / 心肥大 / グルタミン分解 / グルタミン / グルタミナーゼ1 … More / 心筋代謝 / グルタミノリシス / 脂質 / 生体分子 / 分析科学 / 循環器・高血圧 / リハビリテーション / 炎症 / 心血管疾患 / 有酸素運動 / 抗炎症効果 / 運動療法 / 脂質メディエーター / 心臓リハビリテーション / 拡張型心筋症 / 細胞接着分子 / 介在板 / 細胞間接着分子 … More Except Principal Investigator 医療者教育 / 卒前臨床実習 / 地域医療 / 医学教育 / 地域基盤型教育 / 多職種連携教育 / 卒前臨床教育 Less

de novo 脂肪酸合成経路に着目した心臓線維化の分子機序解明と治療法の確立Principal Investigator
- Principal Investigator
  
  小林成美
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
地域医療機関と医学生を教育で結ぶプラットフォームの構築
- Principal Investigator
  
  高桑修
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Nagoya City University
Elucidation of regulatory mechanisms of glutamine metabolism in heart failure and development of novel therapeutic strategiesPrincipal Investigator
- Principal Investigator
  
  Satomi-Kobayashi Seimi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
The regulatory mechanisms of inflammation by exercise via lipid mediatorsPrincipal Investigator
- Principal Investigator
  
  Kobayashi Seimi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kobe University
心臓における細胞間接着分子nectin-2の機能解析Principal Investigator
- Principal Investigator
  
  小林成美
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kobe University

All 2023 2022 2021 2019 2018 2017 2007 2006

All Journal Article Presentation

[Journal Article] Plasma cystine/methionine ratio is associated with left ventricular diastolic function in patients with heart disease2023
- Author(s)
  Asakura Junko、Nagao Manabu、Shinohara Masakazu、Nishimori Makoto、Yoshikawa Sachiko、Iino Takuya、Seto Yutaro、Tanaka Hidekazu、Satomi-Kobayashi Seimi、Ishida Tatsuro、Hirata Ken-ichi、Toh Ryuji
- Journal Title
  
  Heart and Vessels
  
  Volume: 38 Issue: 12 Pages: 1422-1430
- DOI
  10.1007/s00380-023-02302-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08205, KAKENHI-PROJECT-21K08105
[Journal Article] Impact of Frailty on Postoperative Dysphagia in Patients Undergoing Elective Cardiovascular Surgery2022
- Author(s)
  Masato Ogawa, Seimi Satomi-Kobayashi, Naofumi Yoshida, Kodai Komaki, Kazuhiro Izawa, Mari Hamaguchi, Takeshi Inoue, Yoshitada Sakai, Ken-Ichi Hirata, Kenji Okada
- Journal Title
  
  JACC Asia
  
  Volume: 2 Issue: 1 Pages: 114-115
- DOI
  10.1016/j.jacasi.2021.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08105
[Journal Article] Inhibition of glutaminase 1-mediated glutaminolysis improves pathological cardiac remodeling2022
- Author(s)
  Yoshikawa Sachiko、Nagao Manabu、Toh Ryuji、Shinohara Masakazu、Iino Takuya、Irino Yasuhiro、Nishimori Makoto、Tanaka Hidekazu、Satomi-Kobayashi Seimi、Ishida Tatsuro、Hirata Ken-Ichi
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 322 Issue: 5 Pages: H749-H761
- DOI
  10.1152/ajpheart.00692.2021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08491, KAKENHI-PROJECT-21K08105, KAKENHI-PROJECT-20K17081
[Journal Article] Effects of postoperative dietary intake on functional recovery of patients undergoing cardiac surgery.2019
- Author(s)
  Ogawa M, Izawa KP, Satomi-Kobayashi S, Tsuboi Y, Komaki K, Gotake Y, Yoshida N, Wakida K, Uchida J, Sakai Y, Okita Y.
- Journal Title
  
  Nutr Metab Cardiovasc Dis.
  
  Volume: 29 Issue: 1 Pages: 90-96
- DOI
  10.1016/j.numecd.2018.10.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01819, KAKENHI-PROJECT-17K01500
[Journal Article] Efficacy of preoperative amino acid supplements on postoperative physical function and complications in open heart surgery patients: A study protocol for a randomized controlled trial.2019
- Author(s)
  Ogawa M, Yoshida N, Satomi-Kobayashi S, Tsuboi Y, Komaki K, Wakida K, Gotake Y, Inoue T, Tanaka H, Yamashita T, Sakai Y, Izawa KP, Takahashi M, Ogawa W, Hirata KI.
- Journal Title
  
  J Cardiol.
  
  Volume: 印刷中 Issue: 4 Pages: 360-365
- DOI
  10.1016/j.jjcc.2019.03.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01819, KAKENHI-PROJECT-16K08524, KAKENHI-PROJECT-17K01500
[Journal Article] Modulation of High-Density Lipoprotein Function via Cardiac Rehabilitation2018
- Author(s)
  Satomi-Kobayashi S, Ishida T.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 25 Issue: 2 Pages: 128-130
- DOI
  10.5551/jat.ED089
- NAID
  130006328448
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Data Source
  KAKENHI-PROJECT-16K01819
[Journal Article] Impact of delirium on postoperative frailty and long term cardiovascular events after cardiac surgery2017
- Author(s)
  Ogawa Masato、Izawa Kazuhiro P.、Satomi-Kobayashi Seimi、Tsuboi Yasunori、Komaki Kodai、Gotake Yasuko、Sakai Yoshitada、Tanaka Hiroshi、Okita Yutaka
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 12 Pages: 0359-0359
- DOI
  10.1371/journal.pone.0190359
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01819
[Journal Article] Associations of Exercise Tolerance With Hemodynamic Parameters for Pulmonary Arterial Hypertension and for Chronic Thromboembolic Pulmonary Hypertension2017
- Author(s)
  Tsuboi Yasunori、Tanaka Hidekazu、Nishio Ryo、Sawa Takuma、Terashita Daisuke、Nakayama Kazuhiko、Satomi-Kobayashi Seimi、Sakai Yoshitada、Emoto Noriaki、Hirata Ken-ichi
- Journal Title
  
  Journal of Cardiopulmonary Rehabilitation and Prevention
  
  Volume: 37 Issue: 5 Pages: 341-346
- DOI
  10.1097/hcr.0000000000000257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01819
[Journal Article] Preoperative exercise capacity is associated with the prevalence of postoperative delirium in elective cardiac surgery2017
- Author(s)
  Ogawa Masato、Izawa Kazuhiro P.、Satomi-Kobayashi Seimi、Kitamura Aki、Tsuboi Yasunori、Komaki Kodai、Ono Rei、Sakai Yoshitada、Tanaka Hiroshi、Okita Yutaka
- Journal Title
  
  Aging Clinical and Experimental Research
  
  Volume: 30 Issue: 1 Pages: 27-34
- DOI
  10.1007/s40520-017-0736-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01819, KAKENHI-PROJECT-17K01500
[Journal Article] サイトカインによる心筋肥大・線維化・炎症惹起の機序TNF-α2007
- Author(s)
  小林成美, 川嶋成乃亮
- Journal Title
  
  日本臨床増刊号心不全 (上) 65巻
  
  Pages: 215-219
- Data Source
  KAKENHI-PROJECT-18790499
[Presentation] Inhibition of Glutaminase1-dependent Glutaminolysis Improves Pathological Cardiac Remodeling2021
- Author(s)
  吉川　祥子*、長尾　学、杜　隆嗣、篠原　正和、飯野　琢也、西森　誠、入野　康宏、田中　秀和、小林　成美、石田　達郎、平田　健一
- Organizer
  第86回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08105
[Presentation] Inhibition of glutaminase1-mediated glutaminolysis ameliorates angiotensin II-induced cardiac remodeling2021
- Author(s)
  Sachiko Yoshikawa, Manabu Nagao, Ryuji Toh, Masakazu Shinohara, Takuya Iino, Hidekazu Tanaka, Seimi Satomi-Kobayashi, Tatsuro Ishida, Ken-ichi Hirata
- Organizer
  第5回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-21K08105
[Presentation] Nectin-2 is rcquired to prevent cardiac fibrosis and dysfunction in response to chronic pressure overload2007
- Author(s)
  小林成美
- Organizer
  第71回日本循環器学会総会・学術総会
- Place of Presentation
  兵庫県神戸市、神戸国際会議場
- Year and Date
  2007-03-16
- Data Source
  KAKENHI-PROJECT-18790499
[Presentation] Necrin-2 is required to prevent cardiac fibrosis and dysfunction in response to cb ronic pressure overload2006
- Author(s)
  小林成美
- Organizer
  第10回日本心不全学会学術集会
- Place of Presentation
  東京都千代田区、都市センターホテル
- Year and Date
  2006-10-13
- Data Source
  KAKENHI-PROJECT-18790499

1. 篠原正和 (80437483)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 長尾学 (70866029)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 井澤和大 (10736185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 杜隆嗣 (50379418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 高桑修 (10647332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 柿崎真沙子 (20580872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 松尾洋一 (40381800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山下純世 (90423863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 田中秀和

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kobayashi Seimi 小林 成美

Satomi-Kobayashi Seimi 小林 成美

小林 成美 コバヤシ セイミ

Research Projects

Research Products

Co-Researchers

de novo 脂肪酸合成経路に着目した心臓線維化の分子機序解明と治療法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

地域医療機関と医学生を教育で結ぶプラットフォームの構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of regulatory mechanisms of glutamine metabolism in heart failure and development of novel therapeutic strategiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The regulatory mechanisms of inflammation by exercise via lipid mediatorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心臓における細胞間接着分子nectin-2の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Plasma cystine/methionine ratio is associated with left ventricular diastolic function in patients with heart disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of Frailty on Postoperative Dysphagia in Patients Undergoing Elective Cardiovascular Surgery2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of glutaminase 1-mediated glutaminolysis improves pathological cardiac remodeling2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of postoperative dietary intake on functional recovery of patients undergoing cardiac surgery.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of preoperative amino acid supplements on postoperative physical function and complications in open heart surgery patients: A study protocol for a randomized controlled trial.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modulation of High-Density Lipoprotein Function via Cardiac Rehabilitation2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Impact of delirium on postoperative frailty and long term cardiovascular events after cardiac surgery2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Associations of Exercise Tolerance With Hemodynamic Parameters for Pulmonary Arterial Hypertension and for Chronic Thromboembolic Pulmonary Hypertension2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preoperative exercise capacity is associated with the prevalence of postoperative delirium in elective cardiac surgery2017

Kobayashi Seimi 小林成美

Satomi-Kobayashi Seimi 小林成美

小林成美コバヤシセイミ