MOTOMURA Kyoko 飯沼今日子

… Alternative Names

本村

飯沼今日子(本村今日子) イイヌマキヨウコ

IINUMA Kyoko 飯沼今日子

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Researcher Number	20380644
Affiliation (based on the past Project Information) *help	2015 – 2016: 九州大学, 医学部, 臨床・衛生検査技師 2014: 九州大学, 医学(系)研究科(研究院), その他 2012: 九州大学, 医学(系)研究科(研究院), 技術職員 2012: 九州大学, 大学院・医学研究院, 技術職員 2011: 九州大学, 医学研究院, 技術職員 … More 2010: 九州大学, 大学院・医学研究院, 技術職員 2007: Kyushu Uhiversity, Department of Neurology, Technical Staff 2006: 九州大学, 大学院医学研究院, 技術職員 Less
Review Section/Research Field	Except Principal Investigator Neurology
Keywords	Except Principal Investigator アルツハイマー病 / アミロイドβ蛋白 / p53 / 酸化ストレス / リン酸化タウ蛋白 / 毒性ターン / インスリン分解酵素 / インスリン抵抗性 / アポモルフィン / モデルマウス … More / oxidative stress / neurofibrillary tangle / cognitive function / 3x transgenic mouse / apomorphine sulfate / apoptosis / amyloid β-protein / Alzheimer's disease / 神経保護 / プロテアソーム / 神経原線維変化 / 認知機能 / 3Xトランスジェニックマウス / 塩酸アポモルフィン / アポトーシス / インスリン分泌能 / 記憶機能 / インスリン受容体基質 / 記憶障害 / 3xTg-ADマウス / 糖尿病 / モリス水迷路 / 小胞体ストレス / アミロイドβ / 神経分子病態学 Less

Development of apomorphine therapy targeting insulin resistance in Alzheimer's disease
- Principal Investigator
  
  Ohyagi Yasumasa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Ehime University
  Kyushu University
Development of apomorphine therapy for Alzheimer disease
- Principal Investigator
  
  OHYAGI Yasumasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Development of methods to inhibit apoptosis induced by intracellular amyloid β-protein in Alzheimer's disease
- Principal Investigator
  
  OHYAGI Yasumasa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University

All 2017 2014 2013 2011 2007 2006 Other

All Journal Article Presentation

[Journal Article] Apomorphine therapy for neuronal insulin resistance in a mouse model of Alzheimer's disease2017
- Author(s)
  Nakamura N, Ohyagi Y, Imamura T, Yanagihara YT, Iinuma KM, Soejima N, Murai H, Yamasaki R, Kira J
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461274
[Journal Article] Early inhibition of TNF-α and IL-6 in muscle tissues as a therapy for dystrophinopathy in mdx mice2014
- Author(s)
  Arahata H, Ohyagi Y, Iinuma KM, Tanaka M, Tateishi T, Yamasaki R, Matsushita T, Kira J
- Journal Title
  
  Clinical and Experimental Neuroimmunology
  
  Volume: 5 Issue: 3 Pages: 371-377
- DOI
  10.1111/cen3.12111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461274
[Journal Article] Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer's disease.2013
- Author(s)
  Soejima N, Ohyagi Y, Nakamura N, Himeno E, Iinuma KM, Sakae N, Yamasaki R, Tabira T, Murakami K, Irie K, Kinoshita N, LaFerla FM, Kiyohara Y, Iwaki T, Kira J
- Journal Title
  
  CurrAlzheimer Res
  
  Volume: 10 Issue: 1 Pages: 11-20
- DOI
  10.2174/1567205011310010003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590936, KAKENHI-PROJECT-23890150
[Journal Article] Apomorphine treatment in Alzheimer mice promoting amyloid-β degradation.2011
- Author(s)
  Himeno E, Ohyagi Y, Ma L, Nakamura N, Miyoshi K, Sakae N, Motomura K, Soejima N, Yamasaki R, Hashimoto T, Tabira T, LaFerla FM, Kira J
- Journal Title
  
  Ann Neurol
  
  Volume: 69 Issue: 2 Pages: 248-256
- DOI
  10.1002/ana.22319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590936, KAKENHI-PROJECT-23890150
[Journal Article] Activation of glutathione peroxidase and inhibition of p53-related apoptosis by apomorphine.2011
- Author(s)
  Ma L, Ohyagi Y, Nakamura N, Iinuma KM, Miyoshi K, Himeno E, Soejima N, Yanagihara YT, Sakae N, Yamasaki R, Kira J
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 27 Issue: 1 Pages: 225-237
- DOI
  10.3233/jad-2011-110140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590936, KAKENHI-PROJECT-23890150
[Journal Article] Intraneuronal amyloid β42 enhanced by heating but counteracted by formic acid2007
- Author(s)
  Ohyagi, Y, Tsuruta, Y, Motomura, K, et. al.
- Journal Title
  
  Journal of Neuroscience Methods 159
  
  Pages: 134-138
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590948
[Journal Article] Intraneuronal amyloid β42 enhanced by heating but counteracted by formic acid2007
- Author(s)
  Ohyagi Y, Tsuruta Y, Motomura K, Miyoshi K, Kikuchi H, Iwaki T, Taniwaki T, Kira J
- Journal Title
  
  Journal of Neuroscience Methods 159
  
  Pages: 134-138
- Data Source
  KAKENHI-PROJECT-18590948
[Presentation] Effects of FAD-related mutant presenilin 1(PS1) on caspases activity and apoptosis : Implications in familial Alzheimer's pathogenesis2006
- Author(s)
  Miyoshi, K, Ohyagi, Y, Motomura, K, Tabira, T, Kira, J
- Organizer
  10th International Conference on Alzheimer's Disease and Related Disorders
- Place of Presentation
  Madrid, Spain
- Year and Date
  2006-07-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590948
[Presentation] Pathogenesis of intracellular Aβ42 and p53 : A novel therapeutic target in Alzheimer's disese2006
- Author(s)
  Ohvagi, Y, Miyoshi, K, Ma, L, Motomura, K, Tabira, T, Kira, J
- Organizer
  10th International Conference on Alzheimer's Disease and Related Disorders
- Place of Presentation
  Madrid, Spain
- Year and Date
  2006-07-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590948
[Presentation] Apomorphine treatment improves neuronal insulin resistance in older 3xTg-AD mice
- Author(s)
  Nakamura N, Ohyagi Y, Yanagihara Y, Iinuma K, Kira J
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡市
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26461274
[Presentation] Apomorphine treatment up-regulates IDE and Aβ degradation in 3xTg-AD mice
- Author(s)
  Ohyagi Y, Nakamura N, Yanagihara Y, Iinuma K, Kira J
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡市
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26461274
[Presentation] アルツハイマー病マウスの認知機能における末梢インスリン抵抗性の影響
- Author(s)
  柳原由記、大八木保政、中村憲道、今村友裕、飯沼今日子、吉良潤一
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2014-11-29 – 2014-12-01
- Data Source
  KAKENHI-PROJECT-26461274
[Presentation] Apomorphine Therapy for Neuronal Insulin Resistance in Alzheimer Mice
- Author(s)
  Ohyagi Y, Nakamura N, Yanagihara Y, Iinuma K, Kira J
- Organizer
  26th International Conference of Alzheimer’s Association (AAIC)
- Place of Presentation
  コペンハーゲン、デンマーク
- Year and Date
  2014-07-12 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-26461274

1. OHYAGI Yasumasa (30301336)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. SAKAE Nobutaka (80423523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. NAKABEPPU Yusaku (30180350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山崎亮 (10467946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

MOTOMURA Kyoko 飯沼 今日子

本村

飯沼 今日子(本村今日子) イイヌマ キヨウコ

IINUMA Kyoko 飯沼 今日子

Research Projects

Research Products

Co-Researchers

Development of apomorphine therapy targeting insulin resistance in Alzheimer's disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of apomorphine therapy for Alzheimer disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of methods to inhibit apoptosis induced by intracellular amyloid β-protein in Alzheimer's disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Apomorphine therapy for neuronal insulin resistance in a mouse model of Alzheimer's disease2017

Author(s)

Journal Title

Data Source

[Journal Article] Early inhibition of TNF-α and IL-6 in muscle tissues as a therapy for dystrophinopathy in mdx mice2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer's disease.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Apomorphine treatment in Alzheimer mice promoting amyloid-β degradation.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of glutathione peroxidase and inhibition of p53-related apoptosis by apomorphine.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intraneuronal amyloid β42 enhanced by heating but counteracted by formic acid2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Intraneuronal amyloid β42 enhanced by heating but counteracted by formic acid2007

Author(s)

Journal Title

Data Source

[Presentation] Effects of FAD-related mutant presenilin 1(PS1) on caspases activity and apoptosis : Implications in familial Alzheimer's pathogenesis2006

Author(s)

Organizer

Place of Presentation

Year and Date

Description

Data Source

[Presentation] Pathogenesis of intracellular Aβ42 and p53 : A novel therapeutic target in Alzheimer's disese2006

Author(s)

Organizer

Place of Presentation

Year and Date

Description

Data Source

[Presentation] Apomorphine treatment improves neuronal insulin resistance in older 3xTg-AD mice

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Apomorphine treatment up-regulates IDE and Aβ degradation in 3xTg-AD mice

Author(s)

MOTOMURA Kyoko 飯沼今日子

飯沼今日子(本村今日子) イイヌマキヨウコ

IINUMA Kyoko 飯沼今日子