MORIISHI Takeshi 森石武史

Researcher Number	20380983
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(歯学系), 助教
Affiliation (based on the past Project Information) *help	2014 – 2024: 長崎大学, 医歯薬学総合研究科(歯学系), 助教 2013: 長崎大学, 大学院医歯薬学総合研究科, 助教 2012 – 2013: 長崎大学, 医歯(薬)学総合研究科, 助教 2012: 長崎大学, 医歯(薬)学総合研究科, 技術職員 2007 – 2012: 長崎大学, 大学院・医歯薬学総合研究科, 技術職員 … More 2010: 長崎大学, 医歯薬学総合研究科, 技術職員 2008 – 2009: Nagasaki University, 医歯(薬)学総合研究科, 技術職員 2007: Nagasaki University, 医歯薬学総合研究科, 技術職員 2006: 長崎大学, 大学院医歯薬学総合研究科, 技術職員 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 57010:Oral biological science-related / Basic Section 56020:Orthopedics-related / Mechanobiology / Morphological basic dentistry Except Principal Investigator Morphological basic dentistry / Functional basic dentistry / Medium-sized Section 57:Oral science and related fields / Basic Section 57060:Surgical dentistry-related / Basic Section 56020:Orthopedics-related … More / Basic Section 57070:Developmental dentistry-related / Basic Section 57010:Oral biological science-related / Broad Section I / Mechanobiology / Orthopaedic surgery Less
Keywords	Principal Investigator 骨形成 / 骨芽細胞 / アポトーシス / 骨細胞 / 骨吸収 / 骨芽細胞分化 / Bcl-2 / Bc1-2 / 遺伝子発現解析 / 表面マーカー … More / DMP1 / コンディショナルKOマウス / Sp7 / Runx2 / 未分化間葉系細胞 / dentin matrix protein 1 / 骨形態計測 / マイクロCT / インスリン負荷試験 / 糖負荷試験 / 腹部脂肪解析 / グルコース代謝 / 筋肉 / 精巣 / ノックアウトマウス / 筋量 / テストステロン産生 / 糖代謝 / ホルモン / オステオカルシン / 骨粗鬆症 / 過剰発現マウス / BCLXL / 破骨細胞分化 / マイクロアレイ / メカニカルストレス / 骨細胞ネットワーク / Bcl-XL / 破骨細胞誘導 / RANKL / 破骨細胞活性化因子 / 力学的負荷 / 骨量調節 / メカニカルセンサー / 尾部懸垂 / トランスジェニックマウス … More Except Principal Investigator Runx2 / 骨芽細胞 / 軟骨細胞 / エンハンサー / 細胞・組織 / 発生・分化 / 変形性関節症 / 骨形成 / 転写因子 / 骨細胞 / 骨芽細胞分化 / アイソフォーム / 基礎歯学 / 転写活性 / 歯学 / 発現制御 / 象牙芽細胞突起 / 免疫組織化学 / タウ蛋白質 / 非荷重 / 破骨細胞 / 廃用性骨粗鬆症 / 遺伝子 / メカニカルストレス / Wnt / FGF / 間葉系幹細胞 / 骨粗鬆症 / トランスジェニックマウス / Cbfb / インディアンヘッジホッグ / 骨格系 / Runx1 / 機能重複 / 細胞小器官 / 破歯細胞 / 歯の移動 / 矯正歯科治療 / 歯根吸収 / ヘリオキサンチン類縁体 / 多能性幹細胞 / 骨 / へリオキサンチン類縁体 / P2プロモーター / P1プロモーター / Type II Runx2 / 軟骨形成 / type II Runx2 / Type I Runx2 / Hck / Antxr1 / オステオカルシン / ヘッジホッグ / アポトーシス / 血管進入 / 分化転換 / 骨代謝 / 骨・軟骨組織 / 骨・軟骨 / isoform / 間葉系細胞 / 胎生致死 / 造血 / Supt3 / 創薬 / 口腔解剖学 / Bcl2 / メカルカルストレス / Fkbp5 / ステロイド性骨粗鬆症 / グルココルチコイド / Map1B / 象牙芽細胞分化 / 遺伝子改変マウス / MAP1B / ネスチン / Galnt3 / Pdk4 / マイクロアレー / 免疫電顕 / 骨芽細胞突起 / 免疫電子顕微鏡 / 細胞骨格 / チューブリン / 突起形成 / 細胞分化 / マイクロアレイ / 象牙芽細胞 / 尾部懸垂 / Bc12 / 力学的負荷 / 口腔解剖学(含組織学発生学) / ノックアウト / Fbxo / 組織 / 細胞 / 骨量 / 骨格形成 / Tcf7 / クロマチン修飾 / Mef2 / Dlx5 / 転写制御 / 器官培養 / プロモーター / GFP / ノックアウトマウス / 膜性骨化 / 軟骨内骨化 / コンディショナルノックアウトマウス / 口腔解剖学(含組織学・発生学) Less

生体内でRunx2の骨芽細胞・軟骨細胞における機能に必須なエンハンサー領域の同定
- Principal Investigator
  
  松尾友紀
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagasaki University
歯根吸収発症における細胞小器官分解システム関連蛋白の役割
- Principal Investigator
  
  佛坂斉祉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Nagasaki University
Runx1の軟骨細胞特異的エンハンサーを標的とした変形性関節症治療薬の開発
- Principal Investigator
  
  小守壽文
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nagasaki University
骨芽細胞に分化する新規DMP1陽性未分化間葉系細胞の表面マーカーと遺伝子発現解析Principal Investigator
- Principal Investigator
  
  森石武史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nagasaki University
Elucidation of the function of Type I Runx2 by generating knockout mice and reporter mice
- Principal Investigator
  
  Matsuo Yuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nagasaki University
Investigation of the mechanism of actions of the helioxanthin-derivative and its application as a multi-kinase inhibitor
- Principal Investigator
  
  Ohba Shinsuke
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
  Nagasaki University
Comprehensive understanding of the enhancer cluster that regulates the expression of Indian hedgehog in the skeletal system
- Principal Investigator
  
  大庭伸介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka University
  Nagasaki University
A study of osteocalcin-deficient mice to clarify the bone phenotypes and extraskeletal functionsPrincipal Investigator
- Principal Investigator
  
  MORIISHI Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagasaki University
Elucidation of the mechanism in the regulation of chondrocyte-specific Runx2 enhancer and development of the drug for osteoarthritis
- Principal Investigator
  
  Komori Toshihisa
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Nagasaki University
Elucidation of the function of Supt3 in skeletal formation and its interaction with Runx2 promoter.
- Principal Investigator
  
  MATSUO Yuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
A study of increase bone volume using transgenic mice with osteoblasts that express proliferation and anti-apoptotic factorsPrincipal Investigator
- Principal Investigator
  
  MORIISHI Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagasaki University
Analysis of the function of microtubule-associated protein tau (Mapt) and nestin in the formation of odontoblast processes using the genetically modified mice
- Principal Investigator
  
  MIYAZAKI Toshihiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
Studies for expression and function of Runx2 isoforms
- Principal Investigator
  
  KAWANE Tetsuya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Runx2遺伝子の軟骨細胞特異的エンハンサーの同定とその制御機構の解明
- Principal Investigator
  
  小守壽文
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
Elucidation of the pathogenesis of disuse osteoporosis and steroid-induced osteoporosis using Fkbp5 knockout mice
- Principal Investigator
  
  KOMORI Toshihisa
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Elucidation of the transcriptional regulation of Runx2 and development of the drugs for osteoporosis and osteoarthritis
- Principal Investigator
  
  KOMORI Toshihisa
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
Molecular morphological examination about the formation of processes in the osteoblasts and odontoblasts
- Principal Investigator
  
  MIYAZAKI Toshihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
A study of mechanical stress response genes via osteocyte networkPrincipal Investigator
- Principal Investigator
  
  MORIISHI Takeshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Mechanobiology
- Research Institution
  Nagasaki University
Identification and functional analysis of a novel substrate of Pdk4 in the regulation of osteoclastogenesis in the unloaded condition
- Principal Investigator
  
  KOMORI Toshihisa
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
The mechanism of transcriptional regulation of Runx2 gene and the program of skeletal development
- Principal Investigator
  
  KOMORI Toshihisa
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
Functional analysis of a mechanical stress responsible geneFbxo32 on bone volume regulation
- Principal Investigator
  
  IZUMI Shinichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Mechanobiology
- Research Institution
  Nagasaki University
The molecule mechanism of the bone mass regulation by a bone cell network
- Principal Investigator
  
  KOMORI Toshihisa
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
The role of anti-apoptotic Bcl-X_L in bone formation and maintenance of bone massPrincipal Investigator
- Principal Investigator
  
  MORIISHI Takeshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
骨芽細胞・軟骨細胞制御因子Runx2を調節する化合物のスクリーニング系の開発
- Principal Investigator
  
  小守壽文
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagasaki University
Study of osteoclast activating factor when mechanical stress changes through osteoblast controlled by osteocytePrincipal Investigator
- Principal Investigator
  
  (MORIISHI Takeshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagasaki University
Elucidation of the mechanism of skeletal development using Runx2 and Cbfb conditional knockout mice
- Principal Investigator
  
  KOMORI Toshihisa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
アポトーシス抑制遺伝子Bcl-2の骨の形成および維持における機能解明Principal Investigator
- Principal Investigator
  
  森石武史
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagasaki University

[Journal Article] Runx2 Regulates Galnt3 and Fgf23 Expressions and Galnt3 Decelerates Osteoid Mineralization by Stabilizing Fgf232024
- Author(s)
  Jiang Qing、Qin Xin、Moriishi Takeshi、Fukuyama Ryo、Katsumata Shinichi、Matsuzaki Hiroshi、Komori Hisato、Matsuo Yuki、Sakane Chiharu、Ito Kosei、Hojo Hironori、Ohba Shinsuke、Komori Toshihisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 4 Pages: 2275-2275
- DOI
  10.3390/ijms25042275
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11805, KAKENHI-PROJECT-23K08591, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-23H00440
[Journal Article] Modeling of intramembranous ossification using human pluripotent stem cell-derived paraxial mesoderm derivatives.2023
- Author(s)
  Ikeda Y., Tani S., Moriishi T., Kuroda A., Matsuo Y., Saeki N., Inui-Yamamoto C., Abe M., Maeda T., Rowe DW., Chung UI., Hojo H., Matsushita Y., Sawase T., Ohba S.
- Journal Title
  
  Regenerative Therapy
  
  Volume: 24 Pages: 536-546
- DOI
  10.1016/j.reth.2023.09.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06295, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-23K21494
[Journal Article] Bcl2l1 Deficiency in Osteoblasts Reduces the Trabecular Bone Due to Enhanced Osteoclastogenesis Likely through Osteoblast Apoptosis2023
- Author(s)
  Moriishi Takeshi、Kawai Yosuke、Fukuyama Ryo、Matsuo Yuki、He You-Wen、Akiyama Haruhiko、Asahina Izumi、Komori Toshihisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 24 Pages: 17319-17319
- DOI
  10.3390/ijms242417319
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-23H00440
[Journal Article] Nupr1 deficiency downregulates HtrA1, enhances SMAD1 signaling, and suppresses age‐related bone loss in male mice2023
- Author(s)
  Murayama Masatoshi、Hirata Hirohito、Shiraki Makoto、Iovanna Juan L.、Yamaza Takayoshi、Kukita Toshio、Komori Toshihisa、Moriishi Takeshi、Ueno Masaya、Morimoto Tadatsugu、Mawatari Masaaki、Kukita Akiko
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 238 Issue: 3 Pages: 566-581
- DOI
  10.1002/jcp.30949
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09360, KAKENHI-PROJECT-20F20407, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-23H00440
[Journal Article] Sp7 Transgenic Mice with a Markedly Impaired Lacunocanalicular Network Induced Sost and Reduced Bone Mass by Unloading2022
- Author(s)
  Moriishi Takeshi、Ito Takuro、Fukuyama Ryo、Qin Xin、Komori Hisato、Kaneko Hitomi、Matsuo Yuki、Yoshida Noriaki、Komori Toshihisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 6 Pages: 3173-3173
- DOI
  10.3390/ijms23063173
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-20K10209, KAKENHI-PROJECT-20F20407
[Journal Article] Osteocytes: Their Lacunocanalicular Structure and Mechanoresponses2022
- Author(s)
  Moriishi Takeshi、Komori Toshihisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 8 Pages: 4373-4373
- DOI
  10.3390/ijms23084373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-20F20407
[Journal Article] Orally administrable peptides derived from egg yolk promote skeletal repair and ameliorate degenerative skeletal disorders in mouse models2022
- Author(s)
  Kitaura Yoshiaki、Nakamura Utano、Awada Chihiro、Yamaguchi Motonori、Kim Mujo、Ikeda Yuki、Matsuo Yuki、Moriishi Takeshi、Sawase Takashi、Chung Ung-il、Hojo Hironori、Ohba Shinsuke
- Journal Title
  
  Regenerative Therapy
  
  Volume: 21 Pages: 584-595
- DOI
  10.1016/j.reth.2022.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-22K10261, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19611, KAKENHI-PROJECT-21K19883
[Journal Article] Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass.2020
- Author(s)
  Moriishi T, Ozasa R, Ishimoto T, Nakano T, Hasegawa T, Miyazaki T, Wenguang L, Fukuyama R, Yuying W, Komori H, Qin X, Amizuka N, Komori T
- Journal Title
  
  PLOS Genet.
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-18H05283
[Journal Article] Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts.2020
- Author(s)
  Xin Qin, Qing Jiang, Kenichi Nagano, Takeshi Moriishi, Toshihiro Miyazaki, Hisato Komori, Kosei Ito, Klaus von der Mark, Chiharu Sakane, Hitomi Kaneko, Toshihisa Komori
- Journal Title
  
  PLOS Genetics
  
  Volume: 16
- NAID
  120006980742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05283
[Journal Article] Lack of reproducibility in osteocalcin-deficient mice.2020
- Author(s)
  Takeshi Moriishi, Toshihisa Komori
- Journal Title
  
  PLoS Genet.
  
  Volume: 16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05283
[Journal Article] Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass2020
- Author(s)
  Moriishi Takeshi、Ozasa Ryosuke、Ishimoto Takuya、Nakano Takayoshi、Hasegawa Tomoka、Miyazaki Toshihiro、Liu Wenguang、Fukuyama Ryo、Wang Yuying、Komori Hisato、Qin Xin、Amizuka Norio、Komori Toshihisa
- Journal Title
  
  PLOS Genetics
  
  Volume: 16 Issue: 5 Pages: 1008586-1008586
- DOI
  10.1371/journal.pgen.1008586
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05254, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-18H02964, KAKENHI-PROJECT-20F20407, KAKENHI-PROJECT-18K09070, KAKENHI-PROJECT-19K18946, KAKENHI-PROJECT-19K24124
[Journal Article] Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy2017
- Author(s)
  Yang Mengyu、Arai Atsushi、Udagawa Nobuyuki、Hiraga Toru、Lijuan Zhao、Ito Susumu、Komori Toshihisa、Moriishi Takeshi、Matsuo Koichi、Shimoda Kouji、Zahalka Ali H.、Kobayashi Yasuhiro、Takahashi Naoyuki、Mizoguchi Toshihide
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 4928-4928
- DOI
  10.1038/s41598-017-05401-1
- NAID
  120006576162
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11798, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11048, KAKENHI-PROJECT-15K11093, KAKENHI-PROJECT-16K15781, KAKENHI-PROJECT-26221310
[Journal Article] Overexpression of BCLXL in Osteoblasts Inhibits Osteoblast Apoptosis and Increases Bone Volume and Strength2016
- Author(s)
  Moriishi T, Fukuyama R, Miyazaki T, Furuichi T, Ito M, Komori T.
- Journal Title
  
  J Bone Miner Res
  
  Volume: 印刷中 Issue: 7 Pages: 1366-1380
- DOI
  10.1002/jbmr.2808
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06797, KAKENHI-PROJECT-15K10482, KAKENHI-PROJECT-26221310, KAKENHI-PROJECT-15K11015, KAKENHI-PROJECT-16K15781
[Journal Article] Cbfb regulates bone development by stabilizing Runx family proteins.2015
- Author(s)
  Qin X, Jiang Q, Matsuo Y, Kawane T, Komori H, Moriishi T, Taniuchi I, Ito K, Kawai Y, Rokutanda S, Izumi S, Komori T.
- Journal Title
  
  Journal of bone and mineral research
  
  Volume: 30 Issue: 4 Pages: 706-714
- DOI
  10.1002/jbmr.2379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861748, KAKENHI-PUBLICLY-26114720, KAKENHI-PROJECT-26253084, KAKENHI-PROJECT-26293109, KAKENHI-PROJECT-15K11016, KAKENHI-PROJECT-15K11048, KAKENHI-PROJECT-15K20364, KAKENHI-PROJECT-26670811, KAKENHI-PROJECT-26290040, KAKENHI-PROJECT-26221310
[Journal Article] Microtubule-associated protein tau (Mapt) is expressed in terminally differentiated odontoblasts and severely down-regulated in morphologically disturbed odontoblasts of Runx2 transgenic mice2015
- Author(s)
  Toshihiro Miyazaki ,Tomomi T. Baba,Masako Mori,Takeshi Moriishi,Toshihisa Komori
- Journal Title
  
  Cell and Tissue Research
  
  Volume: - Issue: 2 Pages: 457-466
- DOI
  10.1007/s00441-015-2135-6
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592771, KAKENHI-PROJECT-26670811, KAKENHI-PROJECT-26221310
[Journal Article] Overexpression of Galnt3 in Chondrocytes Resulted in Dwarfism Due to the Increase of Mucin Type O-glycans and Reduction of Glycosaminoglycans.2014
- Author(s)
  Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T.
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 289 Issue: 38 Pages: 26584-26596
- DOI
  10.1074/jbc.m114.555987
- NAID
  120005906910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670811, KAKENHI-PROJECT-26221310
[Journal Article] Dlx5 and Mef2 Regulate a Novel Runx2 Enhancer for Osteoblast-Specific Expression.2014
- Author(s)
  Kawane T, Komori H, Liu W, Moriishi T, Miyazaki T, Mori M, Matsuo Y, Takada Y, Izumi S, Jiang Q, Nishimura R, Kawai Y, Komori T.
- Journal Title
  
  Journal of bone and mineral research
  
  Volume: - Issue: 9 Pages: 1960-1969
- DOI
  10.1002/jbmr.2240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249062, KAKENHI-PROJECT-24659829, KAKENHI-PROJECT-25293378, KAKENHI-PROJECT-26253084, KAKENHI-PROJECT-26221310
[Journal Article] Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.2014
- Author(s)
  Mizuhashi K, Kanamoto T, Moriishi T, Muranishi Y, Miyazaki T, Terada K, Omori Y, Ito M, Komori T, Furukawa T.
- Journal Title
  
  Human molecular genetics
  
  Volume: - Issue: 11 Pages: 2953-2967
- DOI
  10.1093/hmg/ddu007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22249062, KAKENHI-PROJECT-24659829, KAKENHI-PROJECT-25293070, KAKENHI-PROJECT-25460326, KAKENHI-PROJECT-25670142
[Journal Article] Bcl2 deficiency activates FoxO through Akt inactivation and accelerates osteoblast differentiation2014
- Author(s)
  Moriishi T, Kawai Y, Komori H, Rokutanda S, Eguchi Y, Tsujimoto Y, Asahina I, Komori T
- Journal Title
  
  PLoS One
  
  Volume: 9(1) Issue: 1 Pages: 86629-86629
- DOI
  10.1371/journal.pone.0086629
- NAID
  120006987119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22249062, KAKENHI-PROJECT-24604002, KAKENHI-PROJECT-24659829, KAKENHI-PROJECT-24659913, KAKENHI-PROJECT-25861748
[Journal Article] Overexpression of Cdk6 and Ccnd1 in chondrocytes inhibited chondrocyte maturation and caused p53dependent apoptosis without enhancing proliferation.2013
- Author(s)
  Ito K, Maruyama Z, Sakai A, Izumi S, Moriishi T, Yoshida CA, Miyazaki T, Komori H, Takada K, Kawaguchi H, Komori T.
- Journal Title
  
  Oncogene
  
  Volume: 33 Issue: 14 Pages: 1862-1871
- DOI
  10.1038/onc.2013.130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249062, KAKENHI-PROJECT-24659829, KAKENHI-PROJECT-26290040
[Journal Article] Overexpression of Cdk6 and Ccnd1 in chondrocytes inhibited chondrocyte maturation and caused p53dependent apoptosis without enhancing proliferation2013
- Author(s)
  Ito K, Maruyama Z, Sakai A, Izumi S, Moriishi T, Yoshida CA, Miyazaki T, Komori H, Takada K, Kawaguchi H, Komori T
- Journal Title
  
  Oncogene
  
  Volume: Vol.33 Pages: 1862-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659829
[Journal Article] Overexpression of Cdk6 and Ccnd1 in chondrocytes inhibited chondrocyte maturation and caused p53dependent apoptosis without enhancing proliferation2013
- Author(s)
  Ito K, Maruyama Z, Sakai A, Izumi S, Moriishi T, Yoshida CA, Miyazaki T, Komori H, Takada K, Kawaguchi H, Komori T
- Journal Title
  
  Oncogene
  
  Volume: Vol.33 Pages: 1862-1871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249062
[Journal Article] Pyruvate dehydrogenase kinase 4 induces bone loss at unloading by promoting osteoclastogenesis2012
- Author(s)
  Wang Y, Liu W, Masuyama R, Fukuyama R, Ito M, Zhang Q, Komori H, Murakami T, Moriishi T, Miyazaki T, Kitazawa R, Yoshida CA, Kawai Y, Izumi S, Komori T
- Journal Title
  
  Bone
  
  Volume: 50巻 Pages: 409-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659331
[Journal Article] SP7 inhibits osteoblast differentiation at a late stage in mice2012
- Author(s)
  Yoshida CA, Komori H, Maruyama Z, Miyazaki T, Kawasaki K, Furuichi T, Fukuyama R, Mori M, Yamana K, Nakamura K, Liu W, Toyosawa S, Moriishi T, Kawaguchi H, Takada K, Komori T.
- Journal Title
  
  PLoS One
  
  Volume: 7(3)
- NAID
  120006985432
- Data Source
  KAKENHI-PROJECT-22791771
[Journal Article] SP7 inhibits osteoblast differentiation at a late stage in mice2012
- Author(s)
  Yoshida CA, Komori H, Maruyama Z, Miyazaki T, Kawasaki K, Furuichi T, Fukuyama R, Mori M, Yamana K, Nakamura K, Liu W, Toyosawa S, Moriishi T, Kawaguchi H, Takada K, Komori T
- Journal Title
  
  PLoS One
  
  Volume: 7巻
- NAID
  120006985432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659331
[Journal Article] Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading2012
- Author(s)
  Moriishi T, Fukuyama R, Ito M, Miyazaki T, Maeno T, Kawai Y, Komori H, Komori T
- Journal Title
  
  PLoS One
  
  Volume: 7(6) Issue: 6 Pages: 40143-40143
- DOI
  10.1371/journal.pone.0040143
- NAID
  120006985704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249062, KAKENHI-PROJECT-24659829
[Journal Article] es bone loss at unloading by promoting osteoclastogenesis2012
- Author(s)
  Wang Y, Liu W, Masuyama R, Fukuyama R, Ito M, Zhang Q, Komori H, Murakami T, Moriishi T, Miyazaki T, Kitazawa R, Yoshida CA, Kawai Y, Izumi S, and Komori T
- Journal Title
  
  Bone
  
  Volume: 50 Pages: 409-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22616006
[Journal Article] OBIF, an osteoblast induction factor, plays an essential role in bone formation in association with osteoblastogenesis2012
- Author(s)
  Mizuhashi K, Kanamoto T, Ito M, Moriishi T, Muranishi Y, Omori Y, Terada K, Komori T, Furukawa T
- Journal Title
  
  Development, growth and differentiation
- NAID
  10031136918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659331
[Journal Article] OBIF, an osteoblast induction factor, plays an essential role in bone formation in association with osteoblastogenesis2012
- Author(s)
  Mizuhashi K, Kanamoto T, Ito M, Moriishi T, Muranishi Y, Omori Y, Terada K, Komori T, Furukawa T.
- Journal Title
  
  Dev Growth Differ
- NAID
  10031136918
- Data Source
  KAKENHI-PROJECT-22791771
[Journal Article] Pyruvate dehydrogenase kinase 4 induces bone loss at unloading by promoting osteoclastogenesis2012
- Author(s)
  Wang Y, Liu W, Masuyama R, Fukuyama R, Ito M, Zhang Q, Komori H, Murakami T, Moriishi T, Miyazaki T, Kitazawa R, Yoshida CA, Kawai Y, Izumi S, Komori T.
- Journal Title
  
  Bone
  
  Volume: 50(1) Pages: 409-19
- Data Source
  KAKENHI-PROJECT-22791771
[Journal Article] Early onset of Runx2 expression causes craniosynostosis, ectopic bone formation, and limb defects2011
- Author(s)
  Maeno T, Moriishi T, Yoshida C, Komori H, Kanatani N, Izumi S, Takaoka K, and Komori T
- Journal Title
  
  Bone
  
  Volume: 49 Pages: 673-682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22616006
[Journal Article] Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation, and limb defects2011
- Author(s)
  Maeno T, Moriishi T, Yoshida CA, Komori H, Kanatani N, Izumi S, Takaoka K, Komori T
- Journal Title
  
  Bone
  
  Volume: 49巻 Pages: 673-682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659331
[Journal Article] Overexpression of bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis2011
- Author(s)
  Moriishi T, Maruyama Z, Fukuyama R, Ito M, Miyazaki T, Kitaura H, Ohnishi H, Furuichi T, Kawai Y, Masuyama R, Komori H, Takada K, Kawaguchi H, Komori T
- Journal Title
  
  PLoS One
  
  Volume: 6巻
- NAID
  120006985216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659331
[Journal Article] Overexpression of Bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis2011
- Author(s)
  Moriishi T, Maruyama Z, Fukuyama R, Ito M, Miyazaki T, Kitaura H, Ohnishi H, Furuichi T, Kawai Y, Masuyama R, Komori H, Takada K, Kawaguchi H, Komori T.
- Journal Title
  
  PLoS One
  
  Volume: 6(11)
- NAID
  120006985216
- Data Source
  KAKENHI-PROJECT-22791771
[Journal Article] Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation, and limb defects2011
- Author(s)
  Maeno T, Moriishi T, Yoshida CA, Komori H, Kanatani N, Izumi S, Takaoka K, Komori T
- Journal Title
  
  Bone
  
  Volume: Vol.49 Pages: 673-682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249062
[Journal Article] Overexpression of bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis2011
- Author(s)
  Moriishi T
- Journal Title
  
  PLoS One
  
  Volume: 6巻
- NAID
  120006985216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249062
[Journal Article] Overexpression of Bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis2011
- Author(s)
  Moriishi T, et al
- Journal Title
  
  PLoS One
  
  Volume: 6(11)
- NAID
  120006985216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791771
[Journal Article] Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation, and limb defects2011
- Author(s)
  Maeno T, Moriishi T, Yoshida CA, Komori H, Kanatani N, Izumi S, Takaoka K, Komori T.
- Journal Title
  
  Bone
  
  Volume: 49(4) Pages: 673-82
- Data Source
  KAKENHI-PROJECT-22791771
[Journal Article] Overexpression of bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis2011
- Author(s)
  Moriishi T, Masuyama R, Komori T (他11名)
- Journal Title
  
  PLoS One
  
  Volume: 6(11) Issue: 11 Pages: e27487-e27487
- DOI
  10.1371/journal.pone.0027487
- NAID
  120006985216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249062
[Journal Article] Comparative morphology of the osteocyte lacunocanalicular system in various vertebrates2011
- Author(s)
  Cao L, Moriishi T, Miyazaki T, Iimura T, Hamagaki M, Nakane A, Tamamura Y, Komori T, Yamaguchi A.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 29(6) Pages: 662-70
- NAID
  10030895041
- Data Source
  KAKENHI-PROJECT-22791771
[Journal Article] Overexpression of bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis2011
- Author(s)
  Moriishi T
- Journal Title
  
  PLoS One
  
  Volume: 6巻
- NAID
  120006985216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659331
[Journal Article] Comparative morphology of the osteocyte lacunocanalicular system in various vertebrates2011
- Author(s)
  Cao L, Moriishi T, Miyazaki T, Iimura T, Hamagaki M, Nakane A, Tamamura Y, Komori T, Yamaguchi A
- Journal Title
  
  Journal of bone and mineral metabolism
  
  Volume: 29巻 Pages: 662-670
- NAID
  10030895041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659331
[Journal Article] Ultrastructural analysis of osteoblasts, osteocytes and odontoblasts in Runx2 transgenic mice.2010
- Author(s)
  Miyazaki, T, Moriishi, T, Izumi, S, Baba, T, Komori, T
- Journal Title
  
  J Electr Microsc Technol Med Biol.
  
  Volume: 23(2) Pages: 50-50
- Data Source
  KAKENHI-PROJECT-22791771
[Journal Article] Ultrastructural analysis of osteoblasts, osteocytes and odontoblasts in Runx2 transgenic mice.2009
- Author(s)
  Miyazaki, T, Moriishi, T, Izumi, S, Baba, T, Komori, T
- Journal Title
  
  6th international Symposium on Electron Microscopy in Medicine and Biology
  
  Pages: 67-67
- Data Source
  KAKENHI-PROJECT-20791047
[Journal Article] Ultrastructural analysis of osteoblasts, osteocytes and odontoblasts in Runx2 transgenic mice.2009
- Author(s)
  Miyazaki, T, Moriishi, T, Izumi, S, Baba, T, Komori, T
- Journal Title
  
  6th international Symposium on Electron Microscopy in Medicine and Biology, Kobe, Japan
  
  Pages: 67-67
- Data Source
  KAKENHI-PROJECT-20791047
[Journal Article] Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency2007
- Author(s)
  Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, Miyazaki T, Kitaura H, Nakamura K, Fujita T, Kanatani N, Moriishi T, Yamana K, Liu W, Kawaguchi H, Nakamura K, Komori T
- Journal Title
  
  Dev Dyn 236
  
  Pages: 1876-1890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Human pluripotent stem cell-based systems recapitulating intramembranous ossification.2023
- Author(s)
  Ikeda Y, Tani S, Moriishi T, Kuroda A, Matsuo Y, Inui C, Abe N, Maeda T, Chung UI, Hojo H, Matsushita Y, Sawase T, Ohba S
- Organizer
  International Society for Stem Cell Research 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] 卵黄由来生理活性ペプチドの経口投与は骨粗鬆症と骨形成不全症モデルマウスにおいて骨量と骨強度を改善する.2022
- Author(s)
  北浦義昭, 池田悠希, 森石武史, 鄭雄一, 北條宏徳, 大庭伸介
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19611
[Presentation] オステオカルシンはグルコース代謝・テストステロン産生・筋肉量を調節するホルモンとして機能しない2020
- Author(s)
  森石　武史、宮崎　敏博、大庭　伸介、小守　壽文
- Organizer
  第38回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-18K09070
[Presentation] Osteocalcin is required for the alignment of biological apatite crystallites but not for the regulation of bone formation, glucose metabolism testosterone synthesis, and muscle mass.2019
- Author(s)
  Komori T, Ozasa R, Ishimoto T, Nakano T, Moriishi T
- Organizer
  ECTS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05283
[Presentation] オステオカルシンはアパタイト結晶のコラーゲン線維に沿った配向に必須であり、長軸方向の骨強度を維持する2018
- Author(s)
  森石武史，小笹良輔，中野貴由，宮崎敏博，小守壽文
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05283
[Presentation] オステオカルシンはアパタイト結晶のコラーゲン線維に沿った配向に必須であり、長軸方向の骨強度を維持する2018
- Author(s)
  森石　武史、小笹　良輔、中野　貴由、宮崎　敏博、小守　壽文
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09070
[Presentation] Runx2による頭蓋冠形成制御機構2018
- Author(s)
  秦昕，姜晴，宮崎敏博，森石武史，小守寿人，小守壽文
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05283
[Presentation] Runx2は骨芽細胞分化後の骨基質蛋白質遺伝子発現に必要である2018
- Author(s)
  姜晴，秦昕，宮崎敏博，福山亮，小守寿人，森石武史，伊藤公成，小守壽文
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05283
[Presentation] Elucidation of the functions of Runx2 in differentiated osteoblasts.2017
- Author(s)
  Qin X, Jiang Q, Miyazaki T, Fukuyama R, Komori H, Moriishi T, Ito K, Komori T
- Organizer
  21st international RUNX conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11015
[Presentation] アポトーシス抑制遺伝子BCLXLを骨芽細胞に過剰発現させると骨量が増加し生涯を通して骨量が維持される2016
- Author(s)
  森石武史，福山亮，古市達哉，伊東昌子，小守壽文
- Organizer
  第34回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-26221310
[Presentation] Cbfb1とCbfb2 アイソフォームは骨格形成過程において重要な役割を果たす2016
- Author(s)
  姜晴，秦昕，小守寿人，松尾友紀，宮崎敏博，森石武史，小守壽文
- Organizer
  第58回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-26221310
[Presentation] Cbfb1とCbfb2 アイソフォームは骨格形成過程において重要な役割を果たす2016
- Author(s)
  姜晴，秦昕，小守寿人，松尾友紀，宮崎敏博，森石武史，小守壽文
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-15K11015
[Presentation] PTH アナボリック作用に対する骨髄間葉系幹細胞の寄与2016
- Author(s)
  楊孟雨，溝口利英，宇田川信之，松尾光一，小守壽文，森石武史，小林泰浩，高橋直之
- Organizer
  第34回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-26221310
[Presentation] Cbfb plays important roles in bone development through the stabilization of Run family proteins.2015
- Author(s)
  Qin X,Jiang Q,Matsuo Y,Kawane T,Komori H,Moriishi T,Taniuchi I, Ito K,Kawai Y,Rokutanda S,Izumi S, Komori T.
- Organizer
  The RUNXTranscription Factors in Development and Disease
- Place of Presentation
  Weizmann Institude of Science,Rehovot,Israel
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221310
[Presentation] Cbfb plays important roles in bone development through the stabilization of Run family proteins.2015
- Author(s)
  2.Qin X,Jiang Q,Matsuo Y,Kawane T,Komori H,Moriishi T,Taniuchi I, Ito K,Kawai Y,Rokutanda S,Izumi S, Komori T
- Organizer
  The RUNX Transcription Factors in Development and Disease
- Place of Presentation
  Weizmann Institude of Science,Rehovot,Israel
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670811
[Presentation] 軟骨細胞におけるGalnt3の過剰発現はムチン型O-グリカンを増加させグリコサミノグリカンを減少させることによってdwarfismを引き起こす2015
- Author(s)
  川根徹也, 森石武史, 小守寿人, 小守壽文
- Organizer
  日本骨代謝学会
- Place of Presentation
  京王プラザホテル（東京都・新宿区）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15K11048
[Presentation] 軟骨細胞におけるGlant3の過剰発現はムチン型O-グリカンを増加させグリコサミノグリカンを減少させることによってdwarfismを起こす2015
- Author(s)
  川根徹也、森石武史、小守寿人、小守壽文
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26670811
[Presentation] 軟骨細胞におけるGlant3の過剰発現はムチン型O-グリカンを増加させグリコサミノグリカンを減少させることによってdwarfismを起こす2015
- Author(s)
  川根徹也、森石武史、小守寿人、小守壽文
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26221310
[Presentation] Bcl-2ノックアウトマウスではAktの不活性化によりFoxOが活性化し、骨芽細胞分化が促進する2014
- Author(s)
  森石　武史、小守　寿人、小守　壽文
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場、大阪府大阪市
- Year and Date
  2014-07-24
- Data Source
  KAKENHI-PROJECT-26221310
[Presentation] Cbfbは軟骨細胞分化・増殖および骨芽細胞分化に必要である2014
- Author(s)
  秦昕、松尾友紀、姜晴、森石武史、六反田賢、宮崎敏博、小守壽文
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場、福岡県福岡市
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26221310
[Presentation] Runx2遺伝子の骨芽細胞特異的発現制御機構2014
- Author(s)
  小守　寿人、川根　哲也、森石　武史、高田　美生、小守　壽文
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場、大阪府大阪市
- Year and Date
  2014-07-24
- Data Source
  KAKENHI-PROJECT-26221310
[Presentation] 骨細胞ネットワーク破綻マウスを用いた骨細胞機能解析2013
- Author(s)
  森石武史、伊東拓朗、福田理香、小守壽文
- Organizer
  日本骨代謝学会学術集会
- Place of Presentation
  神戸市神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24604002
[Presentation] 骨細胞ネットワークは骨形成を抑制し、骨芽細胞を介して骨吸収を促進する2012
- Author(s)
  森石　武史、小守　壽文
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  東京都新宿区京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24604002
[Presentation] 骨芽細胞分化における抗アポトーシス分子Bc1-2の役割2010
- Author(s)
  森石武史
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京都新宿区
- Data Source
  KAKENHI-PROJECT-22791771
[Presentation] 骨芽細胞分化における抗アポトーシス分子Bc1-2の役割2010
- Author(s)
  森石武史, 他
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-22616006
[Presentation] 骨芽細胞分化における抗アポトーシス分子Bcl-2の役割2010
- Author(s)
  森石武史
- Organizer
  第28回骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル(東京都)
- Data Source
  KAKENHI-PROJECT-22249062
[Presentation] 骨芽細胞分化における抗アポトーシス分子Bcl-2の役割2010
- Author(s)
  森石武史、和泉伸一、小守壽文
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-22616006
[Presentation] Ultrastructural analysis of osteoblasts, osteocytes and odontoblasts in Runx2 transgenic mice.2009
- Author(s)
  Miyazaki T, Moriishi T, Izumi S, Baba T, Komori T
- Organizer
  6th international Symposium on Electron Microscopy in Medicine and Biology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-20791047
[Presentation] 骨芽細胞特異的Bc1-2過剰発現マウスでは骨芽細胞の分化抑制と骨細胞死が起こる2009
- Author(s)
  森石武史、宮崎敏博、和泉伸一、小守壽文
- Organizer
  第51回歯科基礎医学会
- Place of Presentation
  新潟
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-20791047
[Presentation] Runx2 functions during postnatal bone development2007
- Author(s)
  吉田カロリーナ、宮崎敏博、中村康平、藤田隆司、金谷直子、森石武史、小守壽文
- Organizer
  日本解剖学会第63回九州支部学術集会
- Place of Presentation
  長崎
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] 骨芽細胞特異的Bcl-2トランスジェニックマウスを用いた、骨細胞による骨量調節の検証2007
- Author(s)
  森石武史、その, 他
- Organizer
  日本解剖学会第63回九州支部学術集会
- Place of Presentation
  長崎大学(長崎)
- Data Source
  KAKENHI-PROJECT-18791046
[Presentation] 骨芽細胞特異的にBc1-2を強制発現させたマウスでは、骨細胞にアポトーシスをきたし、尾部懸垂による骨量減少が抑制される2007
- Author(s)
  森石武史、福山亮、伊東昌子、小守壽文
- Organizer
  第27回日本骨形態計測学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] 骨形成におけるセマフォリン7A(Sema7A)の機能に関するノックアウトマウスを用いた解析2007
- Author(s)
  田村暁子、宮崎敏博、三笠昌樹、森石武史、六反田賢、藤田隆司、金谷直子、小守壽文
- Organizer
  日本解剖学会第63回九州支部学術集会
- Place of Presentation
  長崎
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] Coll-Bcl-2トランスジェニックマウスにおける歯牙組織の解析2007
- Author(s)
  江口俊子, 宮崎敏博, 森石武史, 金谷直子, 北浦英樹, 吉田教明, 小守壽文
- Organizer
  日本解剖学会第63回九州支部学術集会
- Place of Presentation
  長崎
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19390465
[Presentation] 骨芽細胞特異的にBc1-2を強制発現させたマウスでは、骨細胞にアポトーシスをきたし、尾部懸垂による骨量減少が抑制される2007
- Author(s)
  森石武史、その, 他
- Organizer
  第27回日本骨形態計測学会
- Place of Presentation
  ハウステンボス(佐世保)
- Data Source
  KAKENHI-PROJECT-18791046
[Presentation] Cbfb は軟骨細胞分化・増殖および骨芽細胞分化に必要である
- Author(s)
  秦昕1、松尾友紀、姜晴、森石武史、六反田賢、宮崎敏博、小守壽文
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡市　福岡国際会議場
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26670811
[Presentation] Runx2遺伝子の骨芽細胞特異的発現制御機構
- Author(s)
  小守　寿人、川根　徹也、森石　武史、高田　美生、小守　壽文
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪市　大阪国際会議場
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-26253084
[Presentation] Bcl-2 ノックアウトマウスではAktの不活性化によりFoxOが活性化し、骨芽細胞分化が促進する
- Author(s)
  森石武史、小守寿人、小守壽文
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪市　大阪国際会議場
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-26670811
[Presentation] Cbfb は軟骨細胞分化・増殖および骨芽細胞分化に必要である
- Author(s)
  秦　昕、松尾　友紀、姜　晴、森石　武史、六反田　賢、宮崎　敏博、小守　壽文
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡市　福岡国際会議場
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26253084
[Presentation] 骨細胞ネットワーク破綻マウスを用いた骨細胞機能解析
- Author(s)
  森石　武史、伊東　拓朗、福田　理香、小守　壽文
- Organizer
  第31回日本骨代謝学会学術集会
- Place of Presentation
  神戸市神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24604002
[Presentation] Runx2遺伝子の骨芽細胞特異的発現制御機構
- Author(s)
  小守寿人、川根徹也、森石武史、高田美生、小守壽文
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪市　大阪国際会議場
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-26670811
[Presentation] Bcl-2 ノックアウトマウスではAktの不活性化によりFoxOが活性化し、骨芽細胞分化が促進する
- Author(s)
  森石　武史、小守　寿人、小守　壽文
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪市　大阪国際会議場
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-26253084

1. KOMORI Toshihisa (00252677)

# of Collaborated Projects: 20 results

# of Collaborated Products: 58 results
2. MIYAZAKI Toshihiro (10174161)

# of Collaborated Projects: 12 results

# of Collaborated Products: 22 results
3. MATSUO Yuki (40792601)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
4. KAWANE Tetsuya (00265208)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
5. FUKUYAMA Ryo (20389117)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
6. MASUYAMA Ritsuko (60297596)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
7. Ohba Shinsuke (20466733)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. IZUMI Shinichi (40264246)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. YOSHIDA Carolina Andrea (50437828)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
10. ITO Masako (10193517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. BABA Tomomi (60189727)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. FUKUDA Rika (30312838)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. 北條宏徳 (80788422)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
14. NAKAYAMA Koji (80150473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KITAURA Hideki (60295087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. HAYASHI Hideki (10218589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 金谷直子 (10380982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
18. 伊藤公成 (00332726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. 姜晴 (00790007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. 佛坂斉祉 (90199513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 佛坂由可 (10244089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 水田賢志 (50717618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ROKUTANDA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. FURUICHI Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. ABE Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. ARAI Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. Takahashi Naoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 坂根千春

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 溝口利英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 小林泰浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 小笹良輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 石本卓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 中野貴由

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 久木田明子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 馬渡正明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MORIISHI Takeshi 森石 武史

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骨芽細胞に分化する新規DMP1陽性未分化間葉系細胞の表面マーカーと遺伝子発現解析Principal Investigator

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A study of osteocalcin-deficient mice to clarify the bone phenotypes and extraskeletal functionsPrincipal Investigator

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A study of increase bone volume using transgenic mice with osteoblasts that express proliferation and anti-apoptotic factorsPrincipal Investigator

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MORIISHI Takeshi 森石武史