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Hojo Hironori  北條 宏徳

ORCIDConnect your ORCID iD *help
Researcher Number 80788422
Other IDs
Affiliation (Current) 2023: 東京大学, 大学院医学系研究科(医学部), 准教授
Affiliation (based on the past Project Information) *help 2019 – 2022: 東京大学, 大学院医学系研究科(医学部), 准教授
2017 – 2018: 東京大学, 大学院医学系研究科(医学部), 助教
Review Section/Research Field
Principal Investigator
Medium-sized Section 57:Oral science and related fields / Surgical dentistry / Basic Section 57060:Surgical dentistry-related
Except Principal Investigator
Medium-sized Section 57:Oral science and related fields / Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Medium-sized Section 90:Biomedical engineering and related fields / Oral Science and related fields / Biomedical engineering/Biomaterial science and engineering / Basic Section 57010:Oral biological science-related / Basic Section 57070:Developmental dentistry-related / Basic Section 37030:Chemical biology-related
Keywords
Principal Investigator
エンハンサー / 一細胞解析 / 骨芽細胞 / 骨形成 / 転写制御 / 骨発生 / エピゲノム / ゲノム編集 / エンハンサースクリーニング / 一細胞RNA-seq … More / Runx2 / 転写因子 / 発生・分化 / 発現制御 / バイオインフォマティクス / 骨修復 / 遺伝子発現機構 / 細胞系譜 / 遺伝子発現制御 / 骨再生 / 細胞系譜実験 / CRISPR / 一細胞CRISPRスクリーニング / SNP … More
Except Principal Investigator
骨再生 / 骨 / 骨代謝 / エピゲノム解析 / 骨格系 / 細胞遊走 / バイオインフォマティクス / ゲノムワイド解析 / in vivoイメージング / 再生医学 / エピゲノム / 再生医工学 / 骨軟骨生物学 / ハイドロゲル / 人工骨 / シグナル / 骨軟骨 / 統合インターフェース / ES細胞 / 骨芽細胞 / 破骨細胞 / ES細胞 / 骨髄 / 多能性前駆細胞 / 幹細胞niche / single cell RNA-seq / RNA-seq / ATAC-seq / 骨髄間葉系幹細胞 / 造血-間葉相互作用 / GREAT解析 / open chromatin analysis / 幹細胞ニッシ / 幹細胞 / 一細胞解析 / hPSCs / 骨誘導 / ヒト多能性幹細胞 / ゲノム編集 / インディアンヘッジホッグ / エンハンサー / 活性硫黄分子種 / 硫黄呼吸 / 臍帯組織 / 次世代シーケンサー / 歯科矯正学 / 神経堤由来細胞 / ミトコンドリア / 変形性関節症 / ケミカルバイオロジー / 軟骨 / ヘリオキサンチン類縁体 / 多能性幹細胞 / 組織リモデリング / 骨欠損 / バイオマテリアル Less
  • Research Projects

    (19 results)
  • Research Products

    (95 results)
  • Co-Researchers

    (61 People)
  •  Study on the role of sulfur respiration in homeostasis and disruption of the skeletal system under hypoxic conditions

    • Principal Investigator
      上條 竜太郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Showa University
  •  Evaluation of properties by epigenome analysis for human umbilical cord-derived stromal cells and research for bone regenerative medicine

    • Principal Investigator
      金澤 三四朗
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      The University of Tokyo
  •  Sp7-Dlx相互作用の顎顔面骨再生における機能の解明と歯科矯正治療への応用

    • Principal Investigator
      大久保 和美
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      The University of Tokyo
  •  Development of effective tissue regeneration method based on single cell genomics of neural crest derived cell

    • Principal Investigator
      上條 竜太郎
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Showa University
  •  ヒト骨発生機構の理解に基づく組織再生研究基盤の構築

    • Principal Investigator
      鄭 雄一
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      The University of Tokyo
  •  Comprehensive understanding of the enhancer cluster regulating the expression of Indian hedgehog in the skeletal system

    • Principal Investigator
      大庭 伸介
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Nagasaki University
  •  Prohibitinの軟骨分化機能解析とその知見を用いた変形性関節症薬の探索

    • Principal Investigator
      下畑 宣行
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      Ritsumeikan University
  •  一細胞CRISPRスクリーニング法を駆使した機能的GWAS-SNP検出法の確立Principal Investigator

    • Principal Investigator
      北條 宏徳
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      The University of Tokyo
  •  Investigation of the mechanism of actions of the helioxanthin-derivative and its application as a multi-kinase inhibitor

    • Principal Investigator
      大庭 伸介
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Nagasaki University
  •  組織リモデリングの理解に基づく骨再生法の開発

    • Principal Investigator
      鄭 雄一
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      The University of Tokyo
  •  骨発生・骨修復におけるエピゲノムダイナミクスの比較解析と骨再生への応用Principal Investigator

    • Principal Investigator
      北條 宏徳
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      The University of Tokyo
  •  In vitro modeling of human bone metabolism using pluripotent stem cell-derived bone organoids

    • Principal Investigator
      OHBA Shinsuke
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Nagasaki University
      The University of Tokyo
  •  Development of functional enhancer screening system by integrating genome editing technology with single-cell RNA-seqPrincipal Investigator

    • Principal Investigator
      Hojo Hironori
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      The University of Tokyo
  •  Elucidation of stem cell signal using genome structure as an index and application to bone regenerative medicine

    • Principal Investigator
      Hoshi Kazuto
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      The University of Tokyo
  •  Identification of regulatory factors contributing to migration or recruitment of osteoblast progenitors by genome-wide approach and the application for bone repair

    • Principal Investigator
      Takato Tsuyoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Oral Science and related fields
    • Research Institution
      The University of Tokyo
  •  Fundamental study of bone regeneration with site-specific epigenome editing

    • Principal Investigator
      Ohba Shinsuke
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nagasaki University
      The University of Tokyo
  •  Understanding of Runx2-mediated hierarichical gene regulatory network in bone formation and application of the network for bone regenerationPrincipal Investigator

    • Principal Investigator
      Hojo Hironori
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Surgical dentistry
    • Research Institution
      The University of Tokyo
  •  Identification of osteoclast-supporting cells and the investigation of the in vivo functions of the cells using mouse ES cells

    • Principal Investigator
      Okayasu Mari
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      The University of Tokyo
  •  Development of 4-dimensional scaffold system that integrates signaling factors and 3-dimensional structural biomaterials

    • Principal Investigator
      Tei Yuichi
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      The University of Tokyo

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book Patent

  • [Book] 先進医療NAVIGATOR 再生医療・細胞医療の研究と産業化の最前線 第2章 14 骨再生医療等の現状と課題2019

    • Author(s)
      北條宏徳,鄭 裕一,大庭伸介
    • Total Pages
      93
    • Publisher
      日本医学出版(先進医療フォーラム 編)
    • ISBN
      9784865770308
    • Data Source
      KAKENHI-PROJECT-18H02998
  • [Journal Article] A neomorphic variant in SP7 alters sequence specificity and causes a high-turnover bone disorder2022

    • Author(s)
      Lui Julian C.、Raimann Adalbert、Hojo Hironori、Dong Lijin、Roschger Paul、Kikani Bijal、Wintergerst Uwe、Fratzl-Zelman Nadja、Jee Youn Hee、Haeusler Gabriele、Baron Jeffrey
    • Journal Title

      Nature Communications

      Volume: 13 Pages: 700-700

    • DOI

      10.1038/s41467-022-28318-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19883
  • [Journal Article] Involvement of activator protein-1 family members in β-catenin and p300 association on the genome of PANC-1 cells2022

    • Author(s)
      Doi Tomomitsu、Hojo Hironori、Ohba Shinsuke、Obayashi Kunie、Endo Motoyoshi、Ishizaki Toshimasa、Katoh Akira、Kouji Hiroyuki
    • Journal Title

      Heliyon

      Volume: 8

    • DOI

      10.1016/j.heliyon.2022.e08890

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-20K08530, KAKENHI-PROJECT-21K07972, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19611, KAKENHI-PROJECT-21K19883
  • [Journal Article] Mesenchymal stromal cells in the bone marrow niche consist of multi-populations with distinct transcriptional and epigenetic properties.2021

    • Author(s)
      Kanazawa Sanshiro、Okada Hiroyuki、Hojo Hironori、Ohba Shinsuke、Iwata Junichi、Komura Makoto、Hikita Atsuhiko、Hoshi Kazuto
    • Journal Title

      Sci Rep

      Volume: 11 Pages: 15811-15811

    • DOI

      10.1038/s41598-021-94186-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K22973, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21H03142, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-21K16703
  • [Journal Article] Induction and expansion of human PRRX1+ limb-bud-like mesenchymal cells from pluripotent stem cells2021

    • Author(s)
      Yamada Daisuke、Nakamura Masahiro、Takao Tomoka、Takihira Shota、Yoshida Aki、Kawai Shunsuke、Miura Akihiro、Ming Lu、Yoshitomi Hiroyuki、Gozu Mai、Okamoto Kumi、Hojo Hironori、Kusaka Naoyuki、Iwai Ryosuke、Nakata Eiji、Ozaki Toshifumi、Toguchida Junya、Takarada Takeshi
    • Journal Title

      Nature Biomedical Engineering

      Volume: 5 Pages: 926-940

    • DOI

      10.1038/s41551-021-00778-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21H02643, KAKENHI-PROJECT-21K07192, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19883
  • [Journal Article] Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin2021

    • Author(s)
      Wang JS, Kamath T, Mazur CM, Mirzamohammadi F, Rotter D, Hojo H, Castro CD, Tokavanich N, Patel R, Govea N, Enishi T, Wu Y, da Silva Martins J, Bruce M, Brooks DJ, Bouxsein ML, Tokarz D, Lin CP, Abdul A, Macosko EZ, Fiscaletti M, Munns CF, Ryder P, Kost-Alimova M, Byrne P, Cimini B, Fujiwara M, Kronenberg HM, Wein MN.
    • Journal Title

      Nature Communications

      Volume: 12 Pages: 6271-6271

    • DOI

      10.1038/s41467-021-26571-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19883
  • [Journal Article] ChIP-Seq Assays from Mammalian Cartilage and Chondrocytes.2021

    • Author(s)
      Hojo H, Ohba S et al.
    • Journal Title

      Methods Mol Biol

      Volume: 2245 Pages: 167-178

    • DOI

      10.1007/978-1-0716-1119-7_12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02998
  • [Journal Article] The Progress of Stem Cell Technology for Skeletal Regeneration.2021

    • Author(s)
      Tani Shoichiro、Okada Hiroyuki、Chung Ung-il、Ohba Shinsuke、Hojo Hironori
    • Journal Title

      Int J Mol Sci

      Volume: 22 Pages: 1404-1404

    • DOI

      10.3390/ijms22031404

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-18K19635, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-20K22973, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21K16703
  • [Journal Article] Stepwise strategy for generating osteoblasts from human pluripotent stem cells under fully defined xeno-free conditions with small-molecule inducers.2020

    • Author(s)
      Zujur Denise、Kanke Kosuke、Onodera Shoko、Tani Shoichiro、Lai Jenny、Azuma Toshifumi、Xin Xiaonan、Lichtler Alexander C.、Rowe David W.、Saito Taku、Tanaka Sakae、Masaki Hideki、Nakauchi Hiromitsu、Chung Ung-il、Hojo Hironori、Ohba Shinsuke
    • Journal Title

      Regen Ther

      Volume: 14 Pages: 19-31

    • DOI

      10.1016/j.reth.2019.12.010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-18K19635, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H03007, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17K11898, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19H03833, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
  • [Journal Article] Hedgehog Activation Regulates Human Osteoblastogenesis.2020

    • Author(s)
      Onodera Shoko、Saito Akiko、Hojo Hironori、Nakamura Takashi、Zujur Denise、Watanabe Katsuhito、Morita Nana、Hasegawa Daigo、Masaki Hideki、Nakauchi Hiromitsu、Nomura Takeshi、Shibahara Takahiko、Yamaguchi Akira、Chung Ung-il、Azuma Toshifumi、Ohba Shinsuke
    • Journal Title

      Stem Cell Reports.

      Volume: 15 Pages: 125-139

    • DOI

      10.1016/j.stemcr.2020.05.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-20H03894, KAKENHI-PROJECT-18H03007
  • [Journal Article] Understanding paraxial mesoderm development and sclerotome specification for skeletal repair.2020

    • Author(s)
      Tani Shoichiro、Chung Ung-il、Ohba Shinsuke、Hojo Hironori
    • Journal Title

      Exp Mol Med

      Volume: 52 Pages: 1166-1177

    • DOI

      10.1038/s12276-020-0482-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-20H03885
  • [Journal Article] Gene regulatory landscape in osteoblast differentiation.2020

    • Author(s)
      Hojo H, Ohba S.
    • Journal Title

      Bone

      Volume: Epub 2020 Pages: 115458-115458

    • NAID

      120006988169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02998
  • [Journal Article] Gene regulatory landscape in osteoblast differentiation.2020

    • Author(s)
      Hojo Hironori、Ohba Shinsuke
    • Journal Title

      BONE

      Volume: 137 Pages: 115458-115458

    • DOI

      10.1016/j.bone.2020.115458

    • NAID

      120006988169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-20H03885
  • [Journal Article] Insights into gene regulatory networks in chondrocytes.2019

    • Author(s)
      Hojo Hironori、Ohba Shinsuke
    • Journal Title

      Int J Mol Sci

      Volume: 20 Pages: 6324-6324

    • DOI

      10.3390/ijms20246324

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998
  • [Journal Article] Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds.2019

    • Author(s)
      Kawata Manabu、Mori Daisuke、Kanke Kosuke、Hojo Hironori、Ohba Shinsuke、Chung Ung-il、Yano Fumiko、Masaki Hideki、Otsu Makoto、Nakauchi Hiromitsu、Tanaka Sakae、Saito Taku
    • Journal Title

      Stem Cell Reports.

      Volume: 13 Pages: 530-544

    • DOI

      10.1016/j.stemcr.2019.07.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K19600, KAKENHI-PROJECT-18K16645, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
  • [Journal Article] ゲノムワイドデータとバイオインフォマティクスに基づく転写制御因子とゲノムDNAの相互作用分析2019

    • Author(s)
      大庭伸介, 北條宏徳
    • Journal Title

      バイオマテリアル-生体材料-

      Volume: 37 Pages: 244-251

    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Journal Article] Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone.2019

    • Author(s)
      Xuan Fengjun、Yano Fumiko、Mori Daisuke、Chijimatsu Ryota、Maenohara Yuji、Nakamoto Hideki、Mori Yoshifumi、Makii Yuma、Oichi Takeshi、Taketo Makoto Mark、Hojo Hironori、Ohba Shinsuke、Chung Ung-il、Tanaka Sakae、Saito Taku
    • Journal Title

      Arthritis Res Ther

      Volume: 21 Pages: 2019-2019

    • DOI

      10.1186/s13075-019-2041-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
  • [Journal Article] Generation of orthotopically functional salivary gland from embryonic stem cells.2018

    • Author(s)
      Tanaka Junichi、Ogawa Miho、Hojo Hironori、Kawashima Yusuke、Mabuchi Yo、Hata Kenji、Nakamura Shiro、Yasuhara Rika、Takamatsu Koki、Irie Tarou、Fukada Toshiyuki、Sakai Takayoshi、Inoue Tomio、Nishimura Riko、Ohara Osamu、Saito Ichiro、Ohba Shinsuke、Tsuji Takashi、Mishima Kenji
    • Journal Title

      Nat Commun

      Volume: 9 Pages: 1-13

    • DOI

      10.1038/s41467-018-06469-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11488, KAKENHI-PROJECT-18K09540, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-17H04011, KAKENHI-PROJECT-17H04373, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-15K06853, KAKENHI-PROJECT-16K11459, KAKENHI-PROJECT-15K15737, KAKENHI-PROJECT-17K19775, KAKENHI-PROJECT-17K17088, KAKENHI-PROJECT-15H02575
  • [Journal Article] Bone regeneration by human dental pulp stem cells using a helioxanthin derivative and cell-sheet technology2018

    • Author(s)
      Fujii Y, Kawase-Koga Y, Hojo H, Yano F, Sato M, Chung UI, Ohba S, Chikazu D.
    • Journal Title

      Stem Cell Research & Therapy

      Volume: 9 Pages: 24-24

    • DOI

      10.1186/s13287-018-0783-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K19744, KAKENHI-PROJECT-26221311, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K15536
  • [Journal Article] Three-dimensional system enabling the maintenance and directed differentiation of pluripotent stem cells under defined conditions.2017

    • Author(s)
      Zujur D, Kanke K, Lichtler AC, Hojo H, Chung UI, Ohba S
    • Journal Title

      Sci Adv.

      Volume: 3

    • DOI

      10.1126/sciadv.1602875

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26713054, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-26221311, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-16H06762, KAKENHI-PROJECT-17H05106
  • [Journal Article] Identification of the gene-regulatory landscape in skeletal development and potential links to skeletal regeneration2017

    • Author(s)
      Hojo H, Chung UI, Ohba S
    • Journal Title

      Regenerative Therapy

      Volume: 6 Pages: 100-107

    • DOI

      10.1016/j.reth.2017.04.001

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19744, KAKENHI-PROJECT-26713054, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-15K15732, KAKENHI-PROJECT-17H05106
  • [Journal Article] Local administration of a hedgehog agonist accelerates fracture healing in a mouse model.2016

    • Author(s)
      Kashiwagi M, Hojo H, Kitaura Y, Maeda Y, Aini H, Takato T, Chung U, Ohba S.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 479 Pages: 772-778

    • DOI

      10.1016/j.bbrc.2016.09.134

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-26221311, KAKENHI-PROJECT-26713054, KAKENHI-PROJECT-26670859, KAKENHI-PROJECT-15K15732
  • [Patent] 椎板細胞の製造方法および該椎板細胞の利用2022

    • Inventor(s)
      大庭伸介、谷彰一郎、北條宏徳、鄭雄一
    • Industrial Property Rights Holder
      大庭伸介、谷彰一郎、北條宏徳、鄭雄一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Patent] 椎板細胞の製造方法および該椎板細胞の利用2021

    • Inventor(s)
      大庭伸介、谷彰一郎、北條宏徳、鄭雄一
    • Industrial Property Rights Holder
      国立大学法人長崎大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-041384
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-18K19635
  • [Patent] 椎板細胞の製造方法および該椎板細胞の利用2021

    • Inventor(s)
      大庭伸介、谷彰一郎、北條宏徳、鄭雄一
    • Industrial Property Rights Holder
      大庭伸介、谷彰一郎、北條宏徳、鄭雄一
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-041384
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Patent] 再生医療用ゲル材料2020

    • Inventor(s)
      酒井崇匡、北條宏徳、谷彰一郎、増井公祐、成田真一
    • Industrial Property Rights Holder
      酒井崇匡、北條宏徳、谷彰一郎、増井公祐、成田真一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] 卵黄由来生理活性ペプチドの経口投与は骨粗鬆症と骨形成不全症モデルマウスにおいて骨量と骨強度を改善する2022

    • Author(s)
      北浦義昭, 粟田ちひろ, 重光隆成, 青笹正義, 山口基徳, 金武祚, 鄭雄一, 北條宏徳, 大庭伸介
    • Organizer
      第21回日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-21K19611
  • [Presentation] Understanding skeletal development through single-cell analysis of human pluripotent stem cell-derived endochondral bone tissues.2022

    • Author(s)
      大庭伸介, 谷彰一郎, 岡田寛之, 鄭雄一, 北條宏徳
    • Organizer
      第127回日本解剖学会総会・全国学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] 骨格形成における遺伝子制御ランドスケープの解明2021

    • Author(s)
      北條宏徳
    • Organizer
      17th Meeting of Bone Biology Forum
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19589
  • [Presentation] 骨髄ニッチを構成する間葉系間質細胞の転写およびエピジェネティック解析による特性解明2021

    • Author(s)
      金澤三四朗, 岡田寛之, 北條宏徳, 大庭伸介、古村真, 疋田温彦, 星和人
    • Organizer
      第6回日本骨免疫学会
    • Data Source
      KAKENHI-PROJECT-21H03142
  • [Presentation] Understanding a Mechanism Underlying Bone Repair Process by Combinational Analysis of Lineage Tracing and Single-Cell RNA Sequencing2021

    • Author(s)
      Mika Nakayama, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Shinsuke Ohba, Hironori Hojo
    • Organizer
      ISSCR 2021
    • Data Source
      KAKENHI-PROJECT-20H03885
  • [Presentation] Elucidating human skeletal development using single-cell analysis by inducing bone tissue formation from human pluripotent stem cells.2021

    • Author(s)
      Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
    • Organizer
      2021 Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] EXPLORING HUMAN SKELETAL DEVELOPMENT USING AN INDUCED HUMAN BONE TISSUE DERIVED FROM HUMAN PLURIPOTENT STEM CELLS2021

    • Author(s)
      Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
    • Organizer
      ISSCR 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19883
  • [Presentation] ヒト多能性幹細胞を用いたヒト骨形成過程の再現と応用2021

    • Author(s)
      谷彰一郎, 岡田寛之, 関真秀, 鈴木穣, 斎藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介
    • Organizer
      第36回日本整形外科学会基礎集会
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Elucidating human skeletal development by single-cell analyses with a model of endochondral bone formation using human pluripotent stem cells.2021

    • Author(s)
      Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
    • Organizer
      ESA (Endocrine Society of Australia)-SRB (Society for Reproductive Biology)-ANZBMS (Australian and New Zealand Bone and Mineral Society) 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03142
  • [Presentation] ヒト多能性幹細胞由来の3次元骨組織誘導とシングルセル・マルチオーム解析を用いたヒト骨形成機構の解明2021

    • Author(s)
      谷彰一郎, 岡田寛之, 関真秀, 鈴木穣, 斎藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介
    • Organizer
      第44回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Elucidating human skeletal development using single-cell analysis by inducing bone tissue formation from human pluripotent stem cells.2021

    • Author(s)
      Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
    • Organizer
      2021 Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19611
  • [Presentation] Understanding a mechanism underlying bone repair process and application for bone regeneration2021

    • Author(s)
      Hironori Hojo
    • Organizer
      SICEM 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19589
  • [Presentation] Understanding a mechanism underlying bone repair process and application for bone regeneration2021

    • Author(s)
      Hironori Hojo
    • Organizer
      SICEM 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03885
  • [Presentation] ヒト多能性幹細胞由来3次元骨組織誘導法と単一細胞解析を用いたヒト骨形成機構の探索2021

    • Author(s)
      谷彰一郎, 岡田寛之, 齋藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介
    • Organizer
      第39回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Understanding a mechanism underlying bone repair process and application for bone regeneration2021

    • Author(s)
      Hironori Hojo
    • Organizer
      SICEM 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19883
  • [Presentation] Understanding a mechanism underlying bone repair process and application for bone regeneration2021

    • Author(s)
      Hironori Hojo
    • Organizer
      SICEM 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05318
  • [Presentation] 骨格形成における遺伝子制御ランドスケープの解明2021

    • Author(s)
      北條宏徳
    • Organizer
      17th Meeting of Bone Biology Forum
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03885
  • [Presentation] Elucidating human skeletal development by integrating single-cell analysis and bone tissue induction using human pluripotent stem cells.2021

    • Author(s)
      Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
    • Organizer
      ISSCR/JSRM International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Elucidating human skeletal development by integrating single-cell analysis and bone tissue induction using human pluripotent stem cells.2021

    • Author(s)
      Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
    • Organizer
      ISSCR/JSRM International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19611
  • [Presentation] ヒト多能性幹細胞を用いた骨形成過程の再現と応用2021

    • Author(s)
      "谷 彰一郎, 岡田 寛之, 関 真秀, 鈴木 穣, 齊藤 琢, 田中 栄, 鄭 雄一, 北條 宏徳, 大庭 伸介 "
    • Organizer
      第36回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-21H04952
  • [Presentation] "ELUCIDATING HUMAN SKELETAL DEVELOPMENT BY INTEGRATING SINGLE-CELL ANALYSIS AND BONE TISSUE INDUCTION USING HUMAN PLURIPOTENT STEM CELLS"2021

    • Author(s)
      Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Taku Saito, Sakae Tanaka, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
    • Organizer
      ISSCR tokyo
    • Data Source
      KAKENHI-PROJECT-21H04952
  • [Presentation] EXPLORING HUMAN SKELETAL DEVELOPMENT USING AN INDUCED HUMAN BONE TISSUE DERIVED FROM HUMAN PLURIPOTENT STEM CELLS2021

    • Author(s)
      Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
    • Organizer
      ISSCR 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04952
  • [Presentation] Exploring human skeletal development using a human bone tissue induced from human pluripotent stem cells.2021

    • Author(s)
      Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
    • Organizer
      International Society for Stem Cell Research 2021 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Exploring human skeletal development using a human bone tissue induced from human pluripotent stem cells.2021

    • Author(s)
      Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
    • Organizer
      International Society for Stem Cell Research 2021 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03142
  • [Presentation] Understanding skeletal development through single-cell analysis of human pluripotent stem cell-derived endochondral bone tissues.2021

    • Author(s)
      大庭伸介, 谷彰一郎, 岡田寛之, 鄭雄一, 北條宏徳
    • Organizer
      第127回日本解剖学会総会・全国学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H03142
  • [Presentation] ヒト多能性幹細胞由来3次元骨組織誘導法と単一細胞解析を用いたヒト骨形成機構の探索2021

    • Author(s)
      谷 彰一郎, 岡田 寛之, 齊藤 琢, 田中 栄, 鄭 雄一, 北條 宏徳, 大庭 伸介
    • Organizer
      第39回日本骨代謝学会
    • Data Source
      KAKENHI-PROJECT-21H04952
  • [Presentation] Elucidating human skeletal development by single-cell analyses with a model of endochondral bone formation using human pluripotent stem cells.2021

    • Author(s)
      Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
    • Organizer
      ESA (Endocrine Society of Australia)-SRB (Society for Reproductive Biology)-ANZBMS (Australian and New Zealand Bone and Mineral Society) 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Elucidating dynamic gene regulatory networks in human skeletal development using single cell analyses on a human pluripotent stem cell-based model of endocohondoral ossification.2021

    • Author(s)
      Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
    • Organizer
      ASHBi Symposium 2021
    • Data Source
      KAKENHI-PROJECT-21K19611
  • [Presentation] Understanding a Mechanism Underlying Bone Repair Process by Combinational Analysis of Lineage Tracing and Single-Cell RNA Sequencing2021

    • Author(s)
      Mika Nakayama, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Shinsuke Ohba, Hironori Hojo
    • Organizer
      ISSCR 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19883
  • [Presentation] Understanding a Mechanism Underlying Bone Repair Process by Combinational Analysis of Lineage Tracing and Single-Cell RNA Sequencing2021

    • Author(s)
      Mika Nakayama, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Shinsuke Ohba, Hironori Hojo
    • Organizer
      ISSCR 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04952
  • [Presentation] Runx2 defines the osteoblast chromatin landscape in skeletal development2020

    • Author(s)
      Hironori Hojo, Taku Saito, Shoko Onodera, Toshifumi Azuma, Ung-il Chung, Masahide Seki, Yutaka Suzuki, Andrew P. McMahon, Shinsuke Ohba
    • Organizer
      American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] Runx2 defines the osteoblast chromatin landscape in skeletal development2020

    • Author(s)
      Hojo H, Saito T, Onodera S, Azuma T, Chung UI, Seki M, Suzuki Y, McMahon AP, Ohba S
    • Organizer
      American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03885
  • [Presentation] Runx2 defines the osteoblast chromatin landscape in skeletal development2020

    • Author(s)
      Hironori Hojo, Taku Saito, Shoko Onodera, Toshifumi Azuma, Ung-il Chung, Masahide Seki, Yutaka Suzuki, Andrew P. McMahon, Shinsuke Ohba
    • Organizer
      American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19636
  • [Presentation] Runx2は骨格発生においてクロマチンランドスケープを規定する2020

    • Author(s)
      北條宏徳、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
    • Organizer
      日本骨代謝学会
    • Data Source
      KAKENHI-PROJECT-18K19636
  • [Presentation] Runx2は骨格発生においてクロマチンランドスケープを規定する2020

    • Author(s)
      北條宏徳、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
    • Organizer
      日本骨代謝学会
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] Runx2 defines the osteoblast chromatin landscape in skeletal development.2020

    • Author(s)
      Hojo H, Saito T, Onodera S, Azuma T, Chung UI, Seki M, Suzuki Y, McMahon AP, Ohba S
    • Organizer
      42nd Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19635
  • [Presentation] Runx2は骨格発生においてクロマチンランドスケープを規定する2020

    • Author(s)
      北條宏徳、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
    • Organizer
      第38回日本骨代謝学会
    • Data Source
      KAKENHI-PROJECT-20H03885
  • [Presentation] Runx2は骨格発生において細胞種特異的な転写制御領域に作用する2019

    • Author(s)
      北條宏徳、山川晃、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
    • Organizer
      第37回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19636
  • [Presentation] De novo missense mutation in SP7 in a patient with cranial hyperostosis, long bone fragility, and increased osteoblast number.2019

    • Author(s)
      Lui J, Raimann A, Dong L, Hojo H, Roschger P, Fratzl-Zelman N, Jee YH, Haeusler G, Baron J
    • Organizer
      2019 Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05106
  • [Presentation] Runx2は骨格発生において細胞種特異的な転写制御領域に作用する2019

    • Author(s)
      北條宏徳、山川晃、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
    • Organizer
      第37回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] Cell-type-distinct regulatory action of Runx2 on the genome underlies its distinct roles in osteoblasts and chondrocytes.2019

    • Author(s)
      Hojo H, Ohba S, Yamakawa A, Guo Q, He X, Saito T, Onodera S, Azuma T, Chung UI, McMahon AP.
    • Organizer
      2019 Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19636
  • [Presentation] Runx2は骨格発生において細胞種特異的な転写制御領域に作用する2019

    • Author(s)
      1.北條宏徳、山川晃、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
    • Organizer
      第37回日本骨代謝学会学術集会,
    • Data Source
      KAKENHI-PROJECT-17H05106
  • [Presentation] Identification of bone marrow mesenchymal stromal cell population and stem cell niche signal.2019

    • Author(s)
      Kanazawa S, Hojo H, Ohba S, Hikita A, Hamada Y, Hoshi K
    • Organizer
      International Society for Stem Cell Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19635
  • [Presentation] A Novel SP7/OSTN Axis Controls Osteocyte Morphology and Function2019

    • Author(s)
      Wang JS, Mirzamohammadi F, Hojo H, Rotter D, Castro Andrade CD, Fiscaletti M, Kronenberg HM, Wein MN
    • Organizer
      2019 Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05106
  • [Presentation] Cell-type-distinct regulatory action of Runx2 on the genome underlies its distinct roles in osteoblasts and chondrocytes.2019

    • Author(s)
      Hojo H, Ohba S, Yamakawa A, Guo Q, He X, Saito T, Onodera S, Azuma T, Chung UI, McMahon AP.
    • Organizer
      2019 Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] A chondrocyte-specific Indian hedgehog enhancer as an OA-driving enhancer.2019

    • Author(s)
      Yamakawa A, Hojo H, Chung UI, Ohba S
    • Organizer
      Orthopedic Research Society 2018 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19636
  • [Presentation] Cell-type-distinct regulatory action of Runx2 on the genome underlies its distinct roles in osteoblasts and chondrocytes2019

    • Author(s)
      Hojo H, Ohba S et al
    • Organizer
      2019 Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02998
  • [Presentation] A chondrocyte-specific indian hedgehog enhancer as an OA-driving enhancer2019

    • Author(s)
      Yamakawa Akira, Hojo Hironori, Chung Ung-il, Ohba Shinsuke
    • Organizer
      ORS 2019 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02998
  • [Presentation] Runx2は骨格発生において細胞種特異的な転写制御領域に作用する.2019

    • Author(s)
      北條宏徳, 山川晃, 齋藤琢, 小野寺晶子, 東俊文, 鄭雄一, 大庭伸介
    • Organizer
      第37回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Cell-type disctinct Runx2 regulatory action underlies its distinct functions in osteoblast and chondrocytes.2019

    • Author(s)
      Hojo H, Ohba S, Yamakawa A, Guo Q, He X, Saito T, Onodera S, Azuma T, Chung UI, McMahon AP
    • Organizer
      American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] A chondrocyte-specifc Indian hedgehog enhancer as an OA-driving enhancer2019

    • Author(s)
      Akira Yamakawa, Hironori Hojo, Ung-il Chung, Shinsuke Ohba
    • Organizer
      Orthopaedic Research Society (ORS) 2019 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Cell-type-distinct regulatory action of Runx2 on the genome underlies its distinct roles in osteoblasts and chondrocytes.2019

    • Author(s)
      Hojo H, Ohba S, Yamakawa A, Guo Q, He X, Saito T, Onodera S, Azuma T, Chung UI, McMahon AP.
    • Organizer
      2019 Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05106
  • [Presentation] Generation of functional salivary gland organoid from mouse embryonic stem cells by Sox9 and Foxc1 transduction.2019

    • Author(s)
      Tanaka J, Ogawa M, Hojo H, Mabuchi Y, Yasuhara R, Takamatsu K, Ohba S, Tsuji T, Mishima K
    • Organizer
      International Society for Stem Cell Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19635
  • [Presentation] Identification of a chondrocyte-specific Indian hedgehog enhancer and Sox9-mediated mechanisms of the enhancer activation2018

    • Author(s)
      Yamakawa A, Hojo H, Chung UI, Ohba S
    • Organizer
      OARSI World Congress on Osteoarthritis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05106
  • [Presentation] Role of Osterix (SP7) in Regulating Osteocyte Biology and Dendrite Formation2018

    • Author(s)
      Mirzamohammadi F, Hojo H, Enishi T, Govea N, Kronenberg HM, Wein MN
    • Organizer
      2018 Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05106
  • [Presentation] Identification of a chondrocyte-specific Indian hedgehog enhancer and Sox9-mediated mechanisms of the enhancer activation2018

    • Author(s)
      Akira Yamakawa, Hironori Hojo, Ung-il Chung, Shinsuke Ohba
    • Organizer
      2018 OARSI World Congress on Osteoarthritis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Identification of a chondrocyte-specific Indian hedgehog enhancer and Sox9-mediated mechanisms of the enhancer activation2018

    • Author(s)
      Yamakawa Akira, Hojo Hironori, Chung Ung-il, Ohba Shinsuke
    • Organizer
      2018 OARSI World Congress on Osteoarthritis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02998
  • [Presentation] 軟骨細胞特異的なIndian hedgehogのエンハンサーの同定とSox9による活性化機構2018

    • Author(s)
      山川晃, 北條宏徳, 鄭雄一, 大庭伸介
    • Organizer
      第33回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] Enhancer network for Ihh transcription in chondrocytes.2017

    • Author(s)
      Yamakawa A, Hojo H, Chung UI, Ohba S
    • Organizer
      Orthopaedic Research Society (ORS) 2017 Annual Meeting
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2017-03-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] Modeling of bone remodeling by three-dimensional co-culture of mouse embryonic stem cell-derived osteoblasts and osteoclast precursors2017

    • Author(s)
      Zujur DC, Hikita A, Kanke K, Hojo H, Chung UI, Ohba S
    • Organizer
      International Society for Stem Cell Research 15th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05106
  • [Presentation] Modeling of bone remodeling by three-dimensional co-culture of mouse embryonic stem cell-derived osteoblasts and osteoclast precursors.2017

    • Author(s)
      Zujur DC, Hikita A, Kanke K, Hojo H, Chung UI, Ohba S
    • Organizer
      International Society for Stem Cell Research 15th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] In vivo bone formation by osteoblasts generated from human induced pluripotent stem cells under fully defined xeno-free conditions.2017

    • Author(s)
      Zujur DC, Kanke K, Hojo H, Onodera S, Azuma T, Chung UI, Ohba S
    • Organizer
      39th Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] 軟骨細胞特異的なIhhのエンハンサーの同定とSox9によるその活性化機構.2017

    • Author(s)
      山川晃, 北條宏徳, 鄭雄一, 大庭伸介
    • Organizer
      第35回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] A system level investigation to unravel mechanisms and potential direct targets of the osteogenic small molecule TH2017

    • Author(s)
      Ichsan M, Kanke K, Hojo H, Chung UI, Ohba S
    • Organizer
      EMBL Conference: Mammalian Genetics and Genomics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05106
  • [Presentation] Modeling of bone remodeling by three-dimensional co-culture of mouse embryonic stem cell-derived osteoblasts and osteoclast precursors.2017

    • Author(s)
      Zujur DC, Hikita A, Kanke K, Hojo H, Chung UI, Ohba S
    • Organizer
      International Society for Stem Cell Research 15th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04403
  • [Presentation] 軟骨細胞におけるエンハンサーネットワークを介したIndian hedgehogの発現制御機構.2017

    • Author(s)
      山川晃, 北條宏徳, 鄭雄一, 大庭伸介
    • Organizer
      第90回日本整形外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] In vivo bone formation by osteoblasts generated from human induced pluripotent stem cells under fully defined xeno-free conditions2017

    • Author(s)
      Zujur DC, Kanke K, Hojo H, Onodera S, Azuma T, Chung UI, Ohba S
    • Organizer
      39th Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05106
  • [Presentation] In vivo bone formation by osteoblasts generated from human induced pluripotent stem cells under fully defined xeno-free conditions.2017

    • Author(s)
      Zujur DC, Kanke K, Hojo H, Onodera S, Azuma T, Chung UI, Ohba S
    • Organizer
      39th Annual Meeting of the American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06312
  • [Presentation] Hedgehog agonist promotes callus formation in a mouse fracture model.2017

    • Author(s)
      Kashiwagi M, Hojo H, Kitaura Y, Maeda Y, Aini H, Takato T, Chung UI, Ohba S
    • Organizer
      IADR/AADR/CADR General Session & Exhibition
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2017-03-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06312
  • 1.  Ohba Shinsuke (20466733)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 73 results
  • 2.  Tei Yuichi (30345053)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 42 results
  • 3.  酒井 崇匡 (70456151)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  岡田 寛之 (10883481)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  Hoshi Kazuto (30344451)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  疋田 温彦 (60443397)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  金澤 三四朗 (60823466)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  森石 武史 (20380983)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  松尾 友紀 (40792601)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  上條 竜太郎 (70233939)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  齋藤 琢 (30456107)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 12.  山田 篤 (50407558)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  Takato Tsuyoshi (90171454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  Okayasu Mari (10610941)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  位高 啓史 (60292926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  菅家 康介 (90779810)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 17.  赤池 孝章 (20231798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  宮本 洋一 (20295132)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  塚崎 雅之 (20829527)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  片桐 岳信 (80245802)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  長村 登紀子 (70240736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  大久保 和美 (10396715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  西條 英人 (80372390)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  矢野 文子 (80529040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 25.  下畑 宣行 (30419709)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  関 真秀 (90749326)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  HATA Kenji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  SAKAI Takayoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  KITAURA Yoshiaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  KASHIWAGI Miki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  AZUMA Toshifumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 32.  MORITA Keiichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  ZUJUR Denise
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  ENDO Motoyoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  DOI Tomomitsu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  井上 富雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  中村 史朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  美島 健二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  安原 理佳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  田中 準一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  川嶋 章弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  西村 理行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  深田 俊幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  田中 謙二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  馬渕 洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  稲田 全規
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  小野寺 晶子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 48.  山口 朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  中村 貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  柴原 孝彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  齋藤 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 52.  齋藤 暁子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 53.  戸田口 淳也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 54.  宝田 剛志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 55.  高尾 知佳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 56.  山田 大祐
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 57.  中田 英二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 58.  森 大典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 59.  河田 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 60.  藤井 朋子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 61.  田中 栄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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