HARA Hideaki 原英彰

… Alternative Names

原英彰ハラヒデアキ

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Researcher Number	20381717
Other IDs
Affiliation (Current)	2025: 岐阜薬科大学, 薬学部, 学長
Affiliation (based on the past Project Information) *help	2020 – 2022: 岐阜薬科大学, 薬学部, 学長 2005 – 2020: 岐阜薬科大学, 薬学部, 教授 2015: 岐阜大学, 薬学部, 教授 2009: 岐阜薬科大, 薬学部, 教授 2007 – 2008: 岐阜薬科大学, 薬科学科, 教授 2006: 岐阜薬科大学, 薬学学科, 教授
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related / Pharmacology in pharmacy Except Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related / Physical pharmacy / Basic Section 49010:Pathological biochemistry-related / Basic Section 42020:Veterinary medical science-related / Drug development chemistry / Nerve anatomy/Neuropathology / Applied pharmacology
Keywords	Principal Investigator PET / 緑内障 / 神経科学 / 眼科学 / 再生医学 / 網膜再生 / サル / 眼圧 / 眼科 / 脳・神経 … More / 薬理学 / 血小板由来成長因子 / TUDCA / PDGF / ゼブラフィッシュ / 網膜神経節細胞 / 網膜 / HGF受容体 / アストロサイト / 網膜発生 / ミクログリア / プログラニュリン / retinal development / retinal regeneration / microglia / Progranulin / Retinal damage / Early therapy / Fundal change / Ophthalmology / Optic nerve damage / High intraocular pressure / Glaucoma / 網膜障害 / 早期診断 / 眼底変化 / 視神経障害 / 高眼圧 / 膜タンパク質ライブラリ / SOD1G93A / Na+,K+-ATPase / MEK/ERK経路 / PI3K/Akt経路 / Na+, K+-ATPase / GluA1 / 記憶 / GPNMB … More Except Principal Investigator 緑内障 / 網膜神経節細胞 / 小胞体ストレス / 網膜 / 一酸化窒素 / アストロサイト / 視神経挫滅モデル / TNF-α / ラット / 視神経挫滅 / リポソーム / 抗酸化作用 / 低分子化合物 / アルツハイマー病 / 神経保護 / 血管新生 / HB-EGF / 中和抗体 / 網膜色素上皮細胞 / 線維化 / 線維性瘢痕 / 脈絡膜血管新生 / 加齢黄斑変性 / エクソソーム / 抗体治療 / 分子シャペロン / ALS / ミスフォールド / 神経変性疾患 / チオール基 / ポリフェノール / 黄斑色素 / 活性酸素 / 抗酸化酵素 / ルテイン / 網膜光障害 / 酸化ストレス / 薬理学 / 神経科学 / 視神経 / aquaporin-9 / aquaporin-4 / グルタミン / TGN-020 / aquaporin 4 / グルタミン酸 / aquaporin / 家兎眼の緑内障手術に対する組織反応 / 緑内障手術と予後 / 緑内障手術と視機能 / 緑内障手術と組織反応 / 眼圧と形態変化 / 緑内障手術 / DDS / 経肺 / ボナック核酸 / 前臨床試験 / 肺疾患 / 点眼 / 核酸医薬 / 眼薬理学 / real time-PCR / endothelin-1 / 活性化グリア細胞 / GFAP / endothelin / iNOS / NF-κB / NFκB / neuro-inflammation / simvastatin / NFκ B / CD68 / スタチン / ミクログリア / p38 / Ox-ATP / IL-1β / BBG / OxATP / 急性眼圧上昇モデル / P2X7受容体 / 眼圧上昇 / P2X7 受容体 / フラボノイド / 神経細胞死 / サル / フェレット / 外側膝状体 / 環状イミド誘導体 / 構造活性相関 / HIF-1 / がん / 血管新生阻害剤 / 医薬分子設計 / 分子設計 / VEGF / 低酸素 / がん微小環境 / 血管新生阻害 / ペプチド / ステロイド / 抗炎症薬 / 経肺投与 / リモートローディング / 微粒子 / 点眼剤 / 局所体内挙動 / 製剤学 / 網羅的遺伝子発現解析 / 高次脳機能 / トランスジェニックマウス / 神経細胞保護 / SIRT1 / 糖尿病 / メタボリック症候群 / 味蕾 / 老化 / 精神疾患 / 運動 / 神経成長抑制因子 / 脳虚血 / 筋萎縮性側索硬化症 / メタロチオネイン / βアミロイド / 糖尿病網膜症 / 高次細胞障害 / 高次機能障害 / 神経再生 / 脳・神経 Less

犬の変性性脊髄症を起こす変異SOD1蛋白質の立体構造解析と治療基盤の構築
- Principal Investigator
  
  神志那弘明
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Gifu University
Discovery of pathogenesis-related biomarkers from blood exosome analysis in glaucomatous optic neuropathy
- Principal Investigator
  
  Shimazawa Masamitsu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Gifu Pharmaceutical University
Investigation of novel drugs for inducing retinal regenerationPrincipal Investigator
- Principal Investigator
  
  Hara Hideaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Gifu Pharmaceutical University
Development of molecular targeted drug using high-resolution epitope mapping: a novel therapeutic strategy for intraocular fibrotic scarring
- Principal Investigator
  
  Nakamura Shinsuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gifu Pharmaceutical University
Studies on how lutein administration enhances antioxidant capacity by increasing reduced thiols
- Principal Investigator
  
  OHIRA Akihiro
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Nagasaki University
Development of therapeutic drugs targeting VGF-modifying peptides in retinal diseases
- Principal Investigator
  
  Shimazawa Masamitsu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
The role of progranulin in retinal regenerationPrincipal Investigator
- Principal Investigator
  
  Hara Hideaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
Structural and morphorogical changes after glaucoma surgery
- Principal Investigator
  
  ISHIDA Kyoko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Toho University
A study for protective mechanisms of VGF, a neurosecretory peptide, in glaucomatous optic nerve degeneration
- Principal Investigator
  
  Shimazawa Masamitsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
Studies on topical application of BONAC nucleic with liposomal formulation for advanced clinical treatment
- Principal Investigator
  
  Takeuchi Hirofumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Gifu Pharmaceutical University
Identification of glycoprotein nonmetastatic melanoma protein B (GPNMB) receptor and effect of GPNMB in higher brain functionPrincipal Investigator
- Principal Investigator
  
  Hara Hideaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Gifu Pharmaceutical University
Involvement of aquaporin in the formation of optic nerve edema and protective effects of blocking the AQP channels.
- Principal Investigator
  
  Oku Hidehiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Osaka Medical College
A study for protective mechanisms of VGF, a neurosecretory peptide, in retinal injury
- Principal Investigator
  
  SHIMAZAWA Masamitsu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
緑内障性神経障害:網膜から高次脳神経及びグリア細胞に及ぶ系統的器質障害機構の解明
- Principal Investigator
  
  相原一
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  The University of Tokyo
Involvement of activated P2X7 receptor in disorder of retinal ganglion cells in animal models of glaucoma
- Principal Investigator
  
  SUGIYAMA Tetsuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Osaka Medical College
Determination of neuro-protective effects of statin on the retinal injuries through activated glial cells.
- Principal Investigator
  
  OKU Hidehiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Osaka Medical College
Novel Dosage form design for ocular and pulmonary drug delivery based on analysis of behavior of nano-particle as drug carrier
- Principal Investigator
  
  TAKEUCHI Hirofumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Gifu Pharmaceutical University
Molecular design and chemical genetic approach of bio-probe for anti-angiogenic therapy
- Principal Investigator
  
  NAGASAWA Hideko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu Pharmaceutical University
Morphological and functional changes in visual cortex after retinal damage and its pharmacological approachPrincipal Investigator
- Principal Investigator
  
  HARA Hideaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
A study of molecular mechanisms of endoplasmic reticulum stress in retinal ganglion cell death
- Principal Investigator
  
  SHIMAZAWA Masamitsu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
Research on the roles of metallothioneins in aging, brain ischemia and metabolic syndrome and drug discover
- Principal Investigator
  
  HOZUMI Isao
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Gifu University
Changes in visual fields and retinal function in high intraocular pressure model of monkeysPrincipal Investigator
- Principal Investigator
  
  HARA Hideaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
SIRT1による神経細胞保護の分子機構の解明
- Principal Investigator
  
  伊藤雅史
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Gifu International Institute of Biotechnology
Damage of retinal ganglion cells : Mechanism of the cell death in the local and central nervous system and protection and regeneration of the neural cells.
- Principal Investigator
  
  ARAIE Makoto
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Ophthalmology
- Research Institution
  The University of Tokyo
緑内障及び糖尻病網膜症の病態におけるアルツハイマー病の関連性について
- Principal Investigator
  
  SHIMAZAWA Masamitsu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University
Functional changes mediated by high-intraocular pressure-induced optic nerve damage in lateral geniculate body and visual cortex of monkeys.Principal Investigator
- Principal Investigator
  
  HARA Hideaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gifu Pharmaceutical University

[Book] Progranulin and Central Nervous System Disorders2019
- Author(s)
  Hara, H., Hosokawa, M., Nakamura, S., Shimohata, T., Nishihara, M.
- Total Pages
  183
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-16K11325
[Book] 非経口投与製剤の開発と応用（リポソームによる薬物の後眼部送達）2013
- Author(s)
  田原耕平, 廣中耕平, 竹内洋文
- Total Pages
  7
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-25293008
[Book] Central changes in glaucoma : Neuroscientific study using animal models, In : The Mystery of Glaucoma (eds. by Tomas Kubena), chapter 172011
- Author(s)
  Imamura K., Shimazawa M., Onoe H., Watanabe Y., Ishii K., Mayama C., Akasaki T., Shimegi S., Sato H., Nakadate K., Hara H., Araie M.
- Total Pages
  24
- Publisher
  InTech, Croatia
- Data Source
  KAKENHI-PROJECT-21592262
[Book] Central changes in glaucoma : Neuroscientific study using animal models, In : The Mystery of Glaucoma2011
- Author(s)
  Imamura K., Shimazawa M., Onoe H., Watanabe Y., Ishii K., Mayama C., Akasaki T., Shimegi S., Sato H., Nakadate K., Hara H. and Araie M.
- Total Pages
  17
- Publisher
  InTech, Croatia
- Data Source
  KAKENHI-PROJECT-21592262
[Book] Biophilia2006
- Author(s)
  原英彰
- Total Pages
  8
- Publisher
  特集 : 視覚メカニズムから探る脳の世界、眼の病気と脳の病気との関係を探る-網膜疾患と脳機能障害
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Therapeutic Effects of Iron Chelation in Atorvastatin-Induced Intracranial Hemorrhage of Zebrafish Larvae2020
- Author(s)
  Nakamura Shinsuke、Saito Yuichi、Gouda Takumi、Imai Takahiko、Shimazawa Masamitsu、Nishimura Yuhei、Hara Hideaki
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 29 Issue: 11 Pages: 105215-105215
- DOI
  10.1016/j.jstrokecerebrovasdis.2020.105215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-19K09936
[Journal Article] Effects of anti-osteoporosis drugs against dexamethasone-induced osteoporosis-like phenotype using a zebrafish scale-regeneration model2020
- Author(s)
  Saito Yuichi、Nakamura Shinsuke、Chinen Naoki、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 143 Issue: 2 Pages: 117-121
- DOI
  10.1016/j.jphs.2020.02.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09936, KAKENHI-PROJECT-17J10301
[Journal Article] A triterpenoid Nrf2 activator, RS9, promotes LC3-associated phagocytosis of photoreceptor outer segments in a p62-independent manner2020
- Author(s)
  Saito Yuichi、Yako Tomohiro、Otsu Wataru、Nakamura Shinsuke、Inoue Yuki、Muramatsu Aomi、Nakagami Yasuhiro、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 152 Pages: 235-247
- DOI
  10.1016/j.freeradbiomed.2020.03.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23707, KAKENHI-PROJECT-17J10301, KAKENHI-PROJECT-19K09936
[Journal Article] Contribution of platelet-derived growth factor signaling to retina regeneration in zebrafish2020
- Author(s)
  Saito Yuichi、Yamaguchi Akihiro、Nakamura Shinsuke、Okuyoshi Hiroyuki、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Neuroscience Letters
  
  Volume: 727 Pages: 134930-134930
- DOI
  10.1016/j.neulet.2020.134930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09936, KAKENHI-PROJECT-17J10301
[Journal Article] Tauroursodeoxycholic Acid Promotes Neuronal Survival and Proliferation of Tissue Resident Stem and Progenitor Cells in Retina of Adult Zebrafish2020
- Author(s)
  Saito Yuichi、Okuyoshi Hiroyuki、Nakamura Shinsuke、Otsu Wataru、Yamaguchi Akihiro、Hitchcock Peter F.、Nagashima Mikiko、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  BPB Reports
  
  Volume: 3 Issue: 3 Pages: 92-96
- DOI
  10.1248/bpbreports.3.3_92
- NAID
  130007944888
- ISSN
  2434-432X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09936
[Journal Article] Long-term effects of 222 nm ultraviolet radiation C sterilizing lamps on mice susceptible to ultraviolet radiation.2020
- Author(s)
  Yamano N, Kunisada M, Kaidzu S, Sugihara K, Nishiaki-Sawada A, Ohashi H, Yoshioka A, Igarashi T, Ohira A, Tanito M, Nishigori C
- Journal Title
  
  Photochem Photobiol
  
  Volume: 96 Issue: 4 Pages: 853-862
- DOI
  10.1111/php.13269
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] The Role of Single-Layered Flap in Temporal Inverted Internal Limiting Membrane Flap Technique for Macular Holes: Pros and Cons.2019
- Author(s)
  Takai Y, Tanito M, Sugihara K, Ohira A
- Journal Title
  
  J Ophthalmol.
  
  Volume: Jun 2 Pages: 5737083-5737083
- DOI
  10.1155/2019/5737083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] Carteolol hydrochloride reduces visible light-induced retinal damage in vivo and BSO/glutamate-induced oxidative stress in vitro.2019
- Author(s)
  Matsuo M, Kuse Y, Takahashi K, Kuwahara K, Tanito M, Kaidzu S, Shimazawa M, Hara H, Ohira A
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 139(2) Issue: 2 Pages: 84-90
- DOI
  10.1016/j.jphs.2018.11.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] Suppression of Light-Induced Retinal Degeneration by Quercetin via the AP-1 Pathway in Rats.2019
- Author(s)
  Koyama Y, Kaidzu S, Kim YC, Matsuoka Y, Ishihara T, Ohira A, Tanito M
- Journal Title
  
  Antioxidants (Basel)
  
  Volume: 8(4) Issue: 4 Pages: 79-79
- DOI
  10.3390/antiox8040079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] Irreversible Photoreceptors and RPE Cells Damage by Intravenous Sodium Iodate in Mice Is Related to Macrophage Accumulation2018
- Author(s)
  Moriguchi Mayu、Nakamura Shinsuke、Inoue Yuki、Nishinaka Anri、Nakamura Maho、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 59 Issue: 8 Pages: 3476-3476
- DOI
  10.1167/iovs.17-23532
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325
[Journal Article] Intravitreal aflibercept protects photoreceptors of mice against excessive light exposure2018
- Author(s)
  Kuse Yoshiki、Takahashi Kei、Inoue Yuki、Izawa Hiroshi、Nakamura Shinsuke、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 137 Issue: 4 Pages: 407-411
- DOI
  10.1016/j.jphs.2018.07.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325
[Journal Article] Effects of ripasudil, a ROCK inhibitor, on retinal edema and nonperfusion area in a retinal vein occlusion murine model.2018
- Author(s)
  Hida Y, Nakamura S, Nishinaka A, Inoue Y, Shimazawa M and Hara H
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 137 Issue: 2 Pages: 129-136
- DOI
  10.1016/j.jphs.2018.06.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325
[Journal Article] Pathophysiological Role of VEGF on Retinal Edema and Nonperfused Areas in Mouse Eyes With Retinal Vein Occlusion2018
- Author(s)
  Nishinaka Anri、Inoue Yuki、Fuma Shinichiro、Hida Yoshifumi、Nakamura Shinsuke、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 59 Issue: 11 Pages: 4701-4701
- DOI
  10.1167/iovs.18-23994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325
[Journal Article] Granulin 1 Promotes Retinal Regeneration in Zebrafish2018
- Author(s)
  Tsuruma Kazuhiro、Saito Yuichi、Okuyoshi Hiroyuki、Yamaguchi Akihiro、Shimazawa Masamitsu、Goldman Daniel、Hara Hideaki
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 59 Issue: 15 Pages: 6057-6057
- DOI
  10.1167/iovs.18-24828
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17J10301, KAKENHI-PROJECT-16K11325
[Journal Article] Transient acceleration of autophagic degradation by pharmacological Nrf2 activation is important for retinal pigment epithelium cell survival2018
- Author(s)
  Saito Yuichi、Kuse Yoshiki、Inoue Yuki、Nakamura Shinsuke、Hara Hideaki、Shimazawa Masamitsu
- Journal Title
  
  Redox Biology
  
  Volume: 19 Pages: 354-363
- DOI
  10.1016/j.redox.2018.09.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17J10301, KAKENHI-PROJECT-16K11325
[Journal Article] VGF nerve growth factor inducible is involved in retinal ganglion cells death induced by optic nerve crush2018
- Author(s)
  Takeuchi Hiroto、Inagaki Satoshi、Morozumi Wataru、Nakano Yukimichi、Inoue Yuki、Kuse Yoshiki、Mizoguchi Takahiro、Nakamura Shinsuke、Funato Michinori、Kaneko Hideo、Hara Hideaki、Shimazawa Masamitsu
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 16443-16443
- DOI
  10.1038/s41598-018-34585-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J14970, KAKENHI-PROJECT-17K11486
[Journal Article] Microglia increases the proliferation of retinal precursor cells during postnatal development2018
- Author(s)
  Kuse Y, Ohuchi K, Nakamura S, Hara H and Shimazawa M
- Journal Title
  
  Molecular Vision
  
  Volume: 24 Pages: 536-545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325
[Journal Article] Protective Effect of Highly Polymeric A-Type Proanthocyanidins from Seed Shells of Japanese Horse Chestnut (Aesculus turbinata BLUME) against Light-Induced Oxidative Damage in Rat Retina2018
- Author(s)
  Ishihara T, Kaidzu S, Kimura H, Koyama Y, Matsuoka Y, Ohira A
- Journal Title
  
  Nutrients
  
  Volume: 10(5) Issue: 5 Pages: 593-593
- DOI
  10.3390/nu10050593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] Exposure to excessive blue LED light damages retinal pigment epithelium and photoreceptors of pigmented mice2018
- Author(s)
  Nakamura Maho、Yako Tomohiro、Kuse Yoshiki、Inoue Yuki、Nishinaka Anri、Nakamura Shinsuke、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Experimental Eye Research
  
  Volume: 177 Pages: 1-11
- DOI
  10.1016/j.exer.2018.07.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11325
[Journal Article] Apolipoprotein E2 and E3, but not E4, promote retinal pathological neovascularization2017
- Author(s)
  Masuda T., Shimazawa M., Hashimoto Y., Kojima A., Nakamura S., Suemori S., Mochizuki K., Kawakami H., Kawase K., and Hara H.
- Journal Title
  
  Investigative Ophthalmology & Visual Science
  
  Volume: 58 Issue: 2 Pages: 1208-1217
- DOI
  10.1167/iovs.16-20539
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J11563, KAKENHI-PROJECT-16K11325
[Journal Article] RS9, a novel Nrf2 activator, attenuates light-induced death of cells of photoreceptor cells and Muller glia cells.2017
- Author(s)
  Inoue Y., Shimazawa M., Noda Y., Nagano R., Otsuka T., Kuse Y., Nakano Y., Tsuruma K., Nakagami Y. and Hara H.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 印刷中 Issue: 5 Pages: 750-765
- DOI
  10.1111/jnc.14029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15J07651, KAKENHI-PROJECT-15J07670, KAKENHI-PROJECT-16K11325
[Journal Article] Nrf2 protects photoreceptor cells from photo-oxidative stress induced by blue light.2017
- Author(s)
  Wan-Ju Chen, Caiying Wu, Zhenhua Xu, Kuse Y., Hara H. and Elia Duh.
- Journal Title
  
  Exp. Eye Res.
  
  Volume: 154 Pages: 151-158
- DOI
  10.1016/j.exer.2016.12.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J07651, KAKENHI-PROJECT-16K11325
[Journal Article] Effects of kallidinogenase on retinal edema and size of non-perfused areas in mice with retinal vein occlusion2017
- Author(s)
  Nishinaka Anri、Fuma Shinichiro、Inoue Yuki、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 134 Issue: 2 Pages: 86-92
- DOI
  10.1016/j.jphs.2017.05.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325
[Journal Article] GPNMB Induces BiP Expression by Enhancing Splicing of BiP Pre-mRNA during the Endoplasmic Reticulum Stress Response2017
- Author(s)
  Noda Yasuhiro、Tsuruma Kazuhiro、Takata Masafumi、Ishisaka Mitsue、Tanaka Hirotaka、Nakano Yusuke、Nagahara Yuki、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 12160-12160
- DOI
  10.1038/s41598-017-11828-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325
[Journal Article] A pharmacological approach in newly established retinal vein occlusion model2017
- Author(s)
  Fuma S., Nishinaka A., Inoue Y., Tsuruma K., Shimazawa M., Kondo M. and Hara H
- Journal Title
  
  Scientific Reports
  
  Volume: 7, 43509 Issue: 1 Pages: 43509-43509
- DOI
  10.1038/srep43509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15J07670, KAKENHI-PROJECT-26462683, KAKENHI-PROJECT-16K11325
[Journal Article] Both Autocrine Signaling and Paracrine Signaling of HB-EGF Enhance Ocular NeovascularizationHighlights2017
- Author(s)
  Inoue Yuki、Shimazawa Masamitsu、Nakamura Shinsuke、Takata Shinsuke、Hashimoto Yuhei、Izawa Hiroshi、Masuda Tomomi、Tsuruma Kazuhiro、Sakaue Tomohisa、Nakayama Hironao、Higashiyama Shigeki、Hara Hideaki
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 1 Pages: 174-185
- DOI
  10.1161/atvbaha.117.310337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11325, KAKENHI-PROJECT-15J07670, KAKENHI-PROJECT-16J11563, KAKENHI-PROJECT-16K20013
[Journal Article] Progranulin deficiency causes the retinal ganglion cell loss during development2017
- Author(s)
  Kuse Yoshiki、Tsuruma Kazuhiro、Mizoguchi Takahiro、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1679-1679
- DOI
  10.1038/s41598-017-01933-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325, KAKENHI-PROJECT-15J07651
[Journal Article] Effects of ticagrelor in a mouse model of ischemic stroke2017
- Author(s)
  Yamauchi Keita、Imai Takahiko、Shimazawa Masamitsu、Iwama Toru、Hara Hideaki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 12088-12088
- DOI
  10.1038/s41598-017-12205-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325
[Journal Article] Movement of retinal vessels toward the optic nerve head after increasing intraocular pressure in monkey eyes with experimental glaucoma2017
- Author(s)
  Kuroda A, Enomoto N, Ishida K, Shimazawa M, Noguchi T, Horai N, Onoe H, Hara H, Tomita G
- Journal Title
  
  Exp Eye Res
  
  Volume: 162 Pages: 110-115
- DOI
  10.1016/j.exer.2017.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462634
[Journal Article] Astaxanthin analogs, adonixanthin and lycopene, activate Nrf2 to prevent light-induced photoreceptor degeneration2017
- Author(s)
  Inoue Yuki、Shimazawa Masamitsu、Nagano Ryota、Kuse Yoshiki、Takahashi Kei、Tsuruma Kazuhiro、Hayashi Masahiro、Ishibashi Takashi、Maoka Takashi、Hara Hideaki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 134 Issue: 3 Pages: 147-157
- DOI
  10.1016/j.jphs.2017.05.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325, KAKENHI-PROJECT-15J07651
[Journal Article] Platelet-Derived Growth Factor-BB Lessens Light-Induced Rod Photoreceptor Damage in Mice2017
- Author(s)
  Takahashi Kei、Shimazawa Masamitsu、Izawa Hiroshi、Inoue Yuki、Kuse Yoshiki、Hara Hideaki
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 58 Issue: 14 Pages: 6299-6299
- DOI
  10.1167/iovs.17-22556
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325, KAKENHI-PROJECT-15J07651, KAKENHI-PROJECT-15J07670
[Journal Article] Progranulin increases phagocytosis by retinal pigment epithelial cells in culture2017
- Author(s)
  Murase Hiromi、Tsuruma Kazuhiro、Kuse Yoshiki、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 95 Issue: 12 Pages: 2500-2510
- DOI
  10.1002/jnr.24081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11325, KAKENHI-PROJECT-15J07651
[Journal Article] CCR3 Is Associated with the Death of a Photoreceptor Cell-line Induced by Light Exposure2017
- Author(s)
  Kuse Yoshiki、Tsuruma Kazuhiro、Kanno Yusuke、Shimazawa Masamitsu、Hara Hideaki
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 8 Pages: 1-8
- DOI
  10.3389/fphar.2017.00207
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11325, KAKENHI-PROJECT-15J07651
[Journal Article] Cilostazol ameliorates collagenase-induced cerebral hemorrhage by protecting the blood brain barrier2017
- Author(s)
  Takagi T, Imai T, Mishiro K, Ishisaka M, Tsujimoto M, Ito H, Nagashima K, Matsukawa H, Tsuruma K, Shimazawa M, Yoshimura S, Kozawa O, Iwama T, Hara H.
- Journal Title
  
  J Cereb Blood Flow Metab.
  
  Volume: 37 Issue: 1 Pages: 123-139
- DOI
  10.1177/0271678x15621499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19960, KAKENHI-PROJECT-16K11325
[Journal Article] Topical Use of Angiopoietin-like Protein 2 RNAi-loaded Lipid Nanoparticles Suppresses Corneal Neovascularization.2016
- Author(s)
  Taketani Y, Usui T, Toyono T, Shima N, Yokoo S, Kimakura M, Yamagami S, Ohno S, Onodera R, Tahara K, Takeuchi H, Kuroda M.
- Journal Title
  
  Mol Ther Nucleic Acids.
  
  Volume: 5 Pages: e292-e292
- DOI
  10.1038/mtna.2016.1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15100, KAKENHI-PROJECT-25293008, KAKENHI-PROJECT-26293088, KAKENHI-PROJECT-26250029, KAKENHI-PROJECT-26461961
[Journal Article] Protective effects of NSP-116, a novel imidazolyl aniline derivative, against light-induced retinal damage in vitro and in vivo2016
- Author(s)
  Izawa H., Shimazawa M., Inoue Y., Uchida S., Moroe H., Tsuruma K. and Hara H.
- Journal Title
  
  Free Radic. Biol. Med
  
  Volume: 96 Pages: 304-312
- DOI
  10.1016/j.freeradbiomed.2016.03.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15J07670, KAKENHI-PROJECT-16K11325
[Journal Article] Pulmonary liposomal formulations encapsulated procaterol hydrochloride by a remote loading method achieve sustained release and extended pharmacological effects.2016
- Author(s)
  Tahara K, Tomida H, Ito Y, Tachikawa S, Onodera R, Tanaka H, Tozuka Y, Takeuchi H
- Journal Title
  
  Int J Pharm.
  
  Volume: 505 Issue: 1-2 Pages: 139-146
- DOI
  10.1016/j.ijpharm.2016.03.031
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860119, KAKENHI-PROJECT-25293008
[Journal Article] Inhalation Properties and Stability of Nebulized Naked siRNA Solution for Pulmonary Therapy2016
- Author(s)
  Tahara K, Hashimoto W, Takeuchi H
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 64 Issue: 1 Pages: 63-67
- DOI
  10.1248/cpb.c15-00615
- NAID
  130005115801
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860119, KAKENHI-PROJECT-25293008
[Journal Article] Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.2016
- Author(s)
  Ono Y., Tsuruma K., Takata M., Shimazawa M. and Hara H.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 23241-23241
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460103
[Journal Article] Advanced particle design of liposomes for drug delivery in oral, pulmonary and ocular administration2015
- Author(s)
  小野寺理沙子, 田原耕平, 竹内洋文
- Journal Title
  
  Drug Delivery System
  
  Volume: 30 Issue: 2 Pages: 121-128
- DOI
  10.2745/dds.30.121
- NAID
  130005083738
- ISSN
  0913-5006, 1881-2732
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-25860119, KAKENHI-PROJECT-25293008
[Journal Article] Involvement of endoplasmic reticulum stress in optic nerve degeneration after chronic high intraocular pressure in DBA/2J mice.2015
- Author(s)
  Ojino K., Shimazawa M., Izawa H., Nakano Y., Tsuruma K. and Hara H
- Journal Title
  
  J. Neurosci. Res.
  
  Volume: 93 Issue: 11 Pages: 1675-1683
- DOI
  10.1002/jnr.23630
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462694
[Journal Article] 非侵襲的な投与方法を可能とする微粒子DDS製剤の開発.2015
- Author(s)
  田原耕平, 竹内洋文
- Journal Title
  
  月刊ファインケミカル
  
  Volume: 1 Pages: 15-21
- Data Source
  KAKENHI-PROJECT-25293008
[Journal Article] The extracellular fragment of GPNMB improves memory and increases hippocampal GluA1 levels in mice.2015
- Author(s)
  Murata K., Yoshino Y., Tsuruma K., Moriguchi S., Oyagi A., Tanaka H., Ishisaka M., Shimazawa M., Fukunaga K., Hara H.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 132 Pages: 583-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460103
[Journal Article] Glycoprotein nonmetastatic melanoma protein B (GPNMB) as a novel neuroprotective factor in cerebral ischemia reperfusion injury.2014
- Author(s)
  Nakano Y., Suzuki Y., Takagi T., Kitashoji A., Ono Y., Tsuruma K., Yoshimura S., Shimazawa M., Iwama T. and Hara H.
- Journal Title
  
  Neuroscience
  
  Volume: 277 Pages: 123-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460103
[Journal Article] Improved automated optic cup segmentation based on detection of blood vessel bends in retinal fundus images2014
- Author(s)
  Hatanaka Y, Nagahata Y, Muramatsu C, Okumura S, Ogohara K, Sawada A, Ishida K, Yamamoto T, Fujita H
- Journal Title
  
  Conf Proc IEEE Eng Med Biol Soc
  
  Volume: 2014 Pages: 126-129
- DOI
  10.1109/embc.2014.6943545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462634
[Journal Article] Systemic simvastatin rescues retinal ganglion cells from optic nerve injury possibly through suppression of astroglial NF-kappaB activation.2014
- Author(s)
  Morishita S, Oku H, Horie T, Tonari M, Kida T, Okubo A, Sugiyama T, Takai S, Hara H, Ikeda T.
- Journal Title
  
  PLoS One.
  
  Volume: ９ Issue: 1 Pages: e84387-e84387
- DOI
  10.1371/journal.pone.0084387
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462763
[Journal Article] Retinal drug delivery using eyedrop preparations of poly-l-lysine-modified liposomes2013
- Author(s)
  Hitoshi Sasaki, Keiichi Karasawa, Kohei Hironaka, Kohei Tahara, Yuichi Tozuka, Hirofumi Takeuchi
- Journal Title
  
  European Journal of Pharmaceutics and Biopharmaceutics
  
  Volume: 83 Issue: 3 Pages: 364-369
- DOI
  10.1016/j.ejpb.2012.10.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293008
[Journal Article] Establishment of the ocular hypertension model using the common marmoset2013
- Author(s)
  Shimazawa, M., Nakamura, S., Miwa, M., Tsuruma, K., Aihara, M., Nakamura, K., Hara, H
- Journal Title
  
  Exp Eye Res
  
  Volume: 111 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] Drug delivery to the ocular posterior segment using lipid emulsion via eye drop administration: Effect of emulsion formulations and surface modification2013
- Author(s)
  Lin Ying, Kohei Tahara and Hirofumi Takeuchi
- Journal Title
  
  International Journal Pharmaceutics
  
  Volume: 453 Issue: 2 Pages: 329-335
- DOI
  10.1016/j.ijpharm.2013.06.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293008
[Journal Article] Establishment of the ocular hypertension model using the common marmoset2013
- Author(s)
  Masamitsu Shimazawa, Shinsuke Nakamura, Miki Miwa, Kazuhiro Tsuruma, Makoto Aihara, Katsuki Nakamura, Hideaki Hara
- Journal Title
  
  Experimental Eye Research
  
  Volume: 111C Pages: 1-8
- DOI
  10.1016/j.exer.2013.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] Preparation of bromfenac-loaded liposomes modified with chitosan for ophthalmic drug delivery and evaluation of physicochemical properties and drug release profile2013
- Author(s)
  Toshimasa Tsukamoto, Kohei Hironaka, Takuya Fujisawa, Daiki Yamaguchi, Kohei Tahara, Yuichi Tozuka, Hirofumi Takeuchi
- Journal Title
  
  Asian journal of pharmaceutical sciences
  
  Volume: 8 Issue: 2 Pages: 104-109
- DOI
  10.1016/j.ajps.2013.07.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293008
[Journal Article] Surface modification of liposomes using polymer–wheat germ agglutinin conjugates to improve the absorption of peptide drugs by pulmonary administration2013
- Author(s)
  Mitsutaka Murata, Takashi Yonamine, Shota Tanaka, Kohei Tahara, Yuichi Tozuka, Hirofumi Takeuchi
- Journal Title
  
  Journal of pharmaceutical sciences
  
  Volume: 102 Issue: 4 Pages: 1281-1289
- DOI
  10.1002/jps.23463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293008, KAKENHI-PROJECT-25860119
[Journal Article] 緑内障:眼圧非依存障害因子への挑戦-ネズミ・サル・そしてヒトへ-2012
- Author(s)
  新家眞、北澤克明、山本哲也、澤田明、岩瀬愛子、山本精一郎、吉村健一、原英彰、嶋澤雅光、伊藤保志、山嶋哲盛、今村和幸、笹岡正顕、太田貴史、水野憲、川北耕二、大橋靖雄、白土城照、山崎芳夫、松本長太、玉置泰裕、相原一、富所敦男、永原幸、山上淳吉、古関信之、石井清、高山淳、長谷川智之、間山千尋、内田彩子、山田秀之、大橋正明、Yi-Ning Chen、佐伯忠賜朗、重枝崇史、村田博、Kelvin Lee、鶴我英和、Mao Nakayama、山岸麗子
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 115 Pages: 213-237
- NAID
  10029367236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Induction of amyloid-β1-42 in the retina and optic nerve head of chronic ocular hypertensive monkeys2012
- Author(s)
  Ito Y, Shimazawa M, Tsuruma K, Mayama C, Ishii K, Onoe H, Aihara M, Araie M, Hara H
- Journal Title
  
  Molecular Vision
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390321
[Journal Article] An alteration in the lateral geniculate nucleus of experimental glaucoma monkeys : In vivo positron emission tomography imaging of glialactivation2012
- Author(s)
  Shimazawa M., Ito Y., Inokuchi Y., Yamanaka H., Nakanishi T., Hayashi T., Ji B., Higuchi M., Suhara T., Imamura K., Araie M., Watanabe Y., Onoe H., Hara H.
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Involvement of endoplasmic reticulum stress in optic nerve degeneration following N-methyl-D-aspartate-induced retinal damage in mice.2012
- Author(s)
  Shimazawa M, Miwa A, Ito Y, Tsuruma K, Aihara M, Hara H.
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 90 Issue: 10 Pages: 1960-1969
- DOI
  10.1002/jnr.23078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390321
[Journal Article] Distinct developmental principles underlie the formation of ipsilateral and contralateral whisker-related exonal patterns of layer 2/3 neurons in the barrel cortex2012
- Author(s)
  Sehara K, Wakimoto M, Ako R, Kawasaki H
- Journal Title
  
  Neuroscience
  
  Volume: 226 Pages: 289-304
- DOI
  10.1016/j.neuroscience.2012.09.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04272, KAKENHI-PROJECT-22390321
[Journal Article] Induction of amyloid-beta(1-42) in the retina and optic nerve head of chronic ocular hypertensive monkeys2012
- Author(s)
  Ito, Y., Shimazawa, M., Tsuruma, K., Mayama, C., Ishii, K., Onoe, H., Aihara, M., Araie, M., Hara, H
- Journal Title
  
  Mol Vis
  
  Volume: 18 Pages: 2647-2657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] An Alteration in the Lateral Geniculate Nucleus of Experimental Glaucoma Monkeys : In vivo Positron Emission Tomography Imaging of Glial Activation2012
- Author(s)
  Shimazawa, M., Ito, Y., Inokuchi, Y., Yamanaka, H., Nakanishi, T., Hayashi, T., Ji, B., Higuchi, M., Suhara, T., Imamura, K., Araie, M., Watanabe, Y., Onoe, H., Hara, H.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] An alteration in the lateral geniculate nucleus of experimental glaucoma monkeys : In vivo positron emission tomography imaging of glial activation.2012
- Author(s)
  Shimazawa M, Ito Y, Inokuchi Y, Yamanaka H, Nakanishi T, Hayashi T, Ji B, Higuchi M, Suhara T, Imamura K, Araie M, Watanabe Y, Onoe H, Hara H.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390321
[Journal Article] Involvement of endoplasmic reticulum stress in optic nerve degeneration following N-methyl-D-aspartate-induced retinal damage in mice2012
- Author(s)
  Shimazawa M, Miwa A, Ito Y, Tsuruma K, Aihara M, Hara H
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390321
[Journal Article] Involvement of endoplasmic reticulum stress in optic nerve degeneration following N-methyl-D-aspartate- induced retinal damage in mice2012
- Author(s)
  Shimazawa, M., Miwa, A., Ito, Y., Tsuruma, K., Aihara, M., Hara, H
- Journal Title
  
  J Neurosci Res
  
  Volume: 90 Pages: 1960-1969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] Pulmonary delivery of elcatonin using surface-modified liposomes to improve systemic absorption : polyvinyl alcohol with a hydrophobic anchor and chitosan oligosaccharide as effective surface modifiers2012
- Author(s)
  Murata M, Nakano K, Tahara K, Tozuka Y, Takeuchi H
- Journal Title
  
  Eur J Pharm Biopharm
  
  Volume: 80 Issue: 2 Pages: 340-346
- DOI
  10.1016/j.ejpb.2011.10.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390011
[Journal Article] An alteration in the lateral geniculate nucleus of experimental glaucoma monkeys : In vivo positron emission tomography imaging of glial activation2012
- Author(s)
  Shimazawa M., Ito Y., Inokuchi Y., Yamanaka H., Nakanishi T., Hayashi T., Ji B., Higuchi M., Suhara T., Imamura K., Araie M., Watanabe Y., Onoe H. and Hara H.
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] An alteration in the lateral geniculate nucleus of experimental glaucoma monkeys: In vivo positoron emission tomography imaging of glial activation2012
- Author(s)
  Shimazawa M., Ito Y., Inokuchi Y., Yamanaka H., Hayashi T., Jin B., Higuchi M., Suhara T., Imamura K., Araie M., Watanabe Y., Onoe H., Hara H
- Journal Title
  
  PLoS one
  
  Volume: 7(1) Issue: 1 Pages: 1-14
- DOI
  10.1371/journal.pone.0030526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500311, KAKENHI-PLANNED-23111009, KAKENHI-PROJECT-23390235, KAKENHI-PROJECT-23592612
[Journal Article] 眼圧非依存障害因子への挑戦-ネズミ・サル・そしてヒトへ-2012
- Author(s)
  新家眞、北澤克明、山本哲也、澤田明、岩瀬愛子、山本精一郎、吉村健一、原英彰、嶋澤雅光、伊藤保志、山嶋哲盛、今村和幸、笹岡正顕、太田貴史、水野憲、川北耕二、大橋靖雄、白土城照、山崎芳夫、松本長太、玉置泰裕、相原一、富所敦男、永原幸、山上淳吉、古関信之、石井清、高山淳、長谷川智之、間山千尋、内田彩子、山田秀之、大橋正明、Yi-Ning Chen、佐伯忠賜朗、重枝崇史、村田博、Kelvin Lee、鶴我英和、Mao Nakayama、山岸麗子、緑内障
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 115 Pages: 213-237
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] SUN N8075, a novel radical scavenger, protects against retinal cell death in mice.2011
- Author(s)
  Masamitsu Shimazawa, Hideaki Hara
- Journal Title
  
  Neurosci.Lett.
  
  Volume: 488 Pages: 87-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model2011
- Author(s)
  Ito Y, Shimazawa M, Inokuchi Y, Yamanaka H, Tsuruma K, Imamura K, Onoe H, Watanabe Y, Aihara M, Araie M, Hara H
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 33 Issue: 5 Pages: 843-55
- DOI
  10.1111/j.1460-9568.2010.07578.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390321, KAKENHI-PROJECT-22500311
[Journal Article] Fluorescence Investigation of the Retinal Delivery of Hydrophilic Compounds via Liposomal Eyedrops2011
- Author(s)
  Hironaka K.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 34 Issue: 6 Pages: 894-897
- DOI
  10.1248/bpb.34.894
- NAID
  130000738067
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00384, KAKENHI-PROJECT-21390011
[Journal Article] PETを用いた緑内障早期診断法の確立2011
- Author(s)
  嶋澤雅光、原英彰
- Journal Title
  
  PETジャーナル
  
  Volume: 13 Pages: 10-11
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Edaravone-loaded liposomes for retinal protection against oxidative stress-induced retinal damage2011
- Author(s)
  Hironaka K.
- Journal Title
  
  European Journal of Pharmaceutics and Biopharmaceutics
  
  Volume: Vol.79 Issue: 1 Pages: 119-125
- DOI
  10.1016/j.ejpb.2011.01.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00384, KAKENHI-PROJECT-21390011
[Journal Article] Involvement ofendoplasmic reticulum stress onneuronal cell death in the lateralgeniculate nucleus in the monkeyglaucoma model.2011
- Author(s)
  Ito Y., Shimazawa M., Inokuchi Y.,Yamanaka H., Tsuruma K., Imamura K.,Onoe H., Watanabe Y., Aihara M., AraieM., Hara H.
- Journal Title
  
  European Journal of Neuroscience 33
  
  Pages: 843-855
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model.2011
- Author(s)
  Ito Y, Shimazawa M, Inokuchi Y, Yamanaka H, Tsuruma K, Imamura K, Onoe H, Watanabe Y, Aihara M, Araie M, Hara H.
- Journal Title
  
  Europian Journal of Neuroscience
  
  Volume: 33 Pages: 843-855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390321
[Journal Article] Edaravone-loaded liposome eyedrops protect against light-induced retinal damage in mice2011
- Author(s)
  Shimazaki H, Hironaka K
- Journal Title
  
  Investigative Ophthalmology & Visual Science
  
  Volume: Vol.34 Issue: 10 Pages: 7289-7297
- DOI
  10.1167/iovs.11-7983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00384, KAKENHI-PROJECT-21390011
[Journal Article] Neuroprotective Effects Of Prostaglandin Analogues On Retinal Ganglion Cell Death Independent Of Intraocular Pressure Reduction2011
- Author(s)
  Yamagishi R, Aihara M, Chen YN, Araie M
- Journal Title
  
  Experimental Eye Research
  
  Volume: 93 Pages: 265-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390321
[Journal Article] Neuronal circuits with whisker-related patterns2011
- Author(s)
  Sehara K., Kawasaki H.
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 43 Pages: 155-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390321
[Journal Article] Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model2011
- Author(s)
  Ito Y., Shimazawa M., Inokuchi Y., Yamanaka H., Tsuruma K., Imamura K., Onoe H., Watanabe Y., Aihara M., Araie M. and Hara H.
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 33 Pages: 843-855
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model2011
- Author(s)
  Masamitsu Shimazawa, Hideaki Hara
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 33 Pages: 843-855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity2011
- Author(s)
  Yamauchi, M., Tsuruma, K., Imai, S/,Nakanishi, T., Umigai, N., Shimazawa, M., Hara, H.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 650 Pages: 110-119
- Data Source
  KAKENHI-PROJECT-23592612
[Journal Article] Neuroprotective effects of flavonoids on hypoxia-, glutamate-, and oxidative stress-induced retinal ganglion cell death2011
- Author(s)
  Nakayama M, Aihara M, Chen YN, Araie M, Tomita-Yokotani K, Iwashina T.
- Journal Title
  
  Molecular Vision
  
  Volume: (In press)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390321
[Journal Article] SUN N8075, anovel radical scavenger, protectsagainst retinal cell death in mice.2011
- Author(s)
  Akane M., Shimazawa M., Inokuchi Y.,Tsuruma K., Hara H.
- Journal Title
  
  Neurosci. Lett 488
  
  Pages: 87-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] An Arylidene-Thiazolidinedione Derivative, GPU-4, without PPARγActivation, Reduces Retinal Neovascularization2011
- Author(s)
  Shinsuke Nakamura, Hideko Nagasawa, Hideaki Hara
- Journal Title
  
  Curr. Neurovasc. Res
  
  Volume: 8(1) Pages: 25-34
- URL
  http://www.benthamdirect.org/pages/b_viewarticle.php?articleID=3165504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390033
[Journal Article] Resistance of metallothionein-III null mice to cadmium-induced acute hepatotoxicity2010
- Author(s)
  Honda A, Komuro H, Hasegawa T, Seko Y, Shimada A, Nagase H, Hozumi I, Inuzuka T, Hara H, Fujiwara Y, SatohM
- Journal Title
  
  J Toxicological Sciences (in press)
- NAID
  10026193349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] A novel calpaininhibitor,((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester (SNJ-1945),reduces murine retinal cell death invitro and in vivo.2010
- Author(s)
  Shimazawa M., Suemori S., Inokuchi Y.,Matsunaga N., Nakajima Y., Oka T.,Yamamoto T., Hara H.
- Journal Title
  
  J. Pharmacol. Exp.Ther 332
  
  Pages: 380-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] Lomerizine. Ca^<2->-channel blocker, protects against neuronal degeneration within the visual center of the brain after retinal damage in mice2010
- Author(s)
  Ito Y., Nakamura S., Tanaka H., Tsuruma K., Shimazawa M., Araie M., Hara H.
- Journal Title
  
  CNS Neuroscience and Therapeutics 16
  
  Pages: 103-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Lomerizine, Ca^<2+>-channel blocker, protects against neuronal degeneration within the visual center of the brain after retinal damage in mice2010
- Author(s)
  Ito Y., Nakamura S., Tanaka H., Tsuruma K., Shimazawa M., Araie M. and Hara H.
- Journal Title
  
  CNS Neuroscience and Therapeutics
  
  Volume: 16 Pages: 103-114
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Resistance of metallothionein-III null mice to cadmium-induced acute hepatotoxicity.2010
- Author(s)
  Honda A, Komuro H, Hasegawa T, Seko Y, Shimada A, Nagase H, Hozumi I, Inuzuka T, Hara H, Fujiwara Y, Satoh M
- Journal Title
  
  J Toxicological Sciences 2
  
  Pages: 209-215
- NAID
  10026193349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] An inducer of VGF protectscells from ER stress-induced celldeath and prolongs survival in the mutant SOD1 animal models of familial ALS.2010
- Author(s)
  Shimazawa M., Tanaka H., Ito Y.,Morimoto N., Tsuruma K., Kadokura M.,Tamura S., Inoue Y., Yamada M.,Takahashi H., Warita H., Aoki M., Hara H.
- Journal Title
  
  PLoS ONE, 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] ポリマーコーティングリポソームによるカルシトニンの経粘膜吸収2010
- Author(s)
  竹内洋文、杉原光
- Journal Title
  
  薬学雑誌
  
  Volume: 130 Pages: 1135-1142
- NAID
  130000342374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390011
[Journal Article] Microarray analysis of the liver in MT-III null mice treated with cadmium.2010
- Author(s)
  Honda A, Komuro H, Nagase H, Hozumi I, Inuzuka T, Hara H, Fujiwara Y, Satoh M
- Journal Title
  
  J Toxicological Sciences 2
  
  Pages: 271-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] An inducer of VGF protects cells from ER stress-induced cell death and prolongs survival in the mutant SOD1 animal models of familial ALS.2010
- Author(s)
  Masamitsu Shimazawa, Hideaki Hara
- Journal Title
  
  PLoS ONE
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Journal Article] Microarray analysis of the liver in MT-III null mice treated with cad mium2010
- Author(s)
  Honda A, Komuro H, Nagase H, Hozumi I, Inuzuka T, Hara H, Fujiwara Y, Satoh M
- Journal Title
  
  J Toxicological Sciences (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Metallothionein-III knockout mice aggravates the neuronal damage after transient focal cerebral ischemia.2009
- Author(s)
  Koumura A, Hamanaka J, Shimazawa M, Honda A, Tsuruma K, Uchida Y, Hozumi I, Satoh M, Inuzuka T, Hara H
- Journal Title
  
  Brain Research 1292
  
  Pages: 148-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Metallothionein-3 deficient mice exhibit abnormalities of psychological behaviors2009
- Author(s)
  Koumura A, Kakefuda K, Honda A, Ito Y, Tsuruma K, Shimazawa M, Uchida Y, Hozumi I, Satoh M, Inuzuka T, Hara H
- Journal Title
  
  Neuroscience Letter 467
  
  Pages: 11-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Effects of Bax-inhibiting Peptides in Retinal Ganglion Cell Death Induced by Glutamate or Oxidative Stress In2009
- Author(s)
  Chen YN, Aihara M, Mao W, Yamada H, Matsuyama S, Araie M
- Journal Title
  
  Vitro Brain Res 1148
  
  Pages: 28-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum(ER)stress-induced retinal cell death2009
- Author(s)
  nokuchi Y, Nakajima Y, Shimazawa M, Kurita T, Kubo M, Saito A, Sajiki H, Kudo T, Aihara M, Imaizumi K, Araie M, Hara H.
- Journal Title
  
  Invest Opthamol Vis Sci 50
  
  Pages: 334-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Design and evaluation of a liposomal delivery system targeting the posterior segment of the eye2009
- Author(s)
  K.Hironaka, Y.Inokuchi, Y.Tozuka, M.Shimazawa, H.Hara, H.Takeuchi
- Journal Title
  
  J.Control.Release 136
  
  Pages: 247-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390011
[Journal Article] Morphological changes in the visual pathway induced by experimental glaucoma in Japanese monkeys.2009
- Author(s)
  Ito Y., Shimazawa M., Chen Y. N., Tsuruma K., Yatnashita T., Araie M., Hara H.
- Journal Title
  
  Exp. Eye Res. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] Metallothionein-III knockout mice aggravates the neuronal damage after transient focal cerebral ischemia2009
- Author(s)
  Koumura A, Hamanaka J, Shimazawa M, Honda A, Tsuruma K, Uchida Y, Hozumi I, Satoh M, Inuzuka T, Hara H.
- Journal Title
  
  Brain Research 1292
  
  Pages: 148-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Involvement of brain-derived neurotrophic factor in time-dependent neurodegeneration in the murine superior colliculus after intravitreal injection of N-methyl-D-aspartate2009
- Author(s)
  Tanaka H., Ito Y., Nakamura S., Shimazawa M. and Hara H.
- Journal Title
  
  Mol. Vision
  
  Pages: 662-669
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Molecular imaging reveals unique degenerative changes in experimental glaucoma.2009
- Author(s)
  Imamura K., Onoe H., Shimazawa M., Nozaki S., Wada Y., K ato K., Nakajima H., Mizuma H., Onoe K., Taniguchi T., Sasaoka M., Hara H., Tanaka S., Araie M., Watanabe Y.
- Journal Title
  
  NeuroReport 20
  
  Pages: 139-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] Effects of prostanoid EP agonists on mouse intraocular pressure.2009
- Author(s)
  Saeki T, Ota T, Aihara M, Araie M.
- Journal Title
  
  nvest Opthamol Vis Sci 50
  
  Pages: 2201-2208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Improved cellular uptake of chitosan-modified PLGA nanospheres by A549 cells2009
- Author(s)
  K.Tahara, T.Sakai, H.Yamamoto, H.Takeuchi, N.Hirashima, Y.Kawasahima
- Journal Title
  
  Int.J.Pharm 382
  
  Pages: 198-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390011
[Journal Article] Metallothionein-3 deficient mice exhibit abnormalities of psychological behaviors.2009
- Author(s)
  Koumura A, Kakefuda K, Honda A, Ito Y, Tsuruma K, Shimazawa M, Uchida Y, Hozumi I, Satoh M, Inuzuka T, Hara H
- Journal Title
  
  Neuroscience Letter 467
  
  Pages: 11-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Design and evaluation of a liposomal delivery system targeting the posterior segment of the eye2009
- Author(s)
  K. Hironaka, Y. Inokuchi, Y. Tozuka, M. Shimazawa, H. Hara, H. Takeuchi
- Journal Title
  
  J. Control. Rel
  
  Volume: 136 Issue: 3 Pages: 247-253
- DOI
  10.1016/j.jconrel.2009.02.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390011
[Journal Article] nvolvement of brain-derived neurotrophic factor in time-dependent neurodegeneration in the murine superior colliculus after intiavitreal injection of N-methyl-D-aspartate2009
- Author(s)
  Tanaka H., Ito Y., Nakamura S., Shimazawa M., Hara H.
- Journal Title
  
  Mol. Vision 15
  
  Pages: 662-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592262
[Journal Article] Changes in visual fields and lateral geniculate nucleus in monkey laser-induced high intraocular pressure model2008
- Author(s)
  Sasaoka M., Nakamura K., Shimazawa M., Ito Y., Araie M. and Hara H.
- Journal Title
  
  Exp. Eye Res 86
  
  Pages: 770-782
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] Metallothionein-3(GIF)is expressed in the brain and various peripheral organs of the rat.2008
- Author(s)
  Hozumi I, Suzuki J S, Kanazawa H, Hara A, Saio M, Inuzuka T, Miyairi S, Naganuma A, Tohyama C.
- Journal Title
  
  Amotrophic Lateral Sclerosis (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Metallothionein-3 (GIF) is expressed in the brain and various peripheral organs of the rat.2008
- Author(s)
  Hozumi I, Suzuki J S, Kanazawa H, Hara A, Saio M, Inuzuka T, Miyairi S, Naganuma A, Tohyama C.
- Journal Title
  
  Neuroscience Letters 438
  
  Pages: 54-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Lysyl oxidase-like 1 gene polymorphisms in Japanese patients with primary open angle glaucoma and exfoliation syndrome2008
- Author(s)
  F MABUCHI, Y SAKURADA, K KASHIWAGI, Z YAMAGATA, H IIJIMA, S TSUKAHARA
- Journal Title
  
  Molecular Vision 14
  
  Pages: 1303-1308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Imaging Mouse Retinal Ganglion Cells and Their Loss in vivo by a Fundus Camera in the Normal and Ischemia-Reperfusion Model2008
- Author(s)
  Murata H, Aihara M, Chen YN, Ota T, Numaga J, Araie M
- Journal Title
  
  Invest Ophthalmol Vis Sci 49
  
  Pages: 5546-5552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Metallothionein-3(GIF)is expressed in the brain and various peripheral organs of the rat.2008
- Author(s)
  Hozumi I, Suzuki J S, Kanazawa H, Hara A, Saio M, Inuzuka T, Miyairi S, Naganuma A, Tohyama C
- Journal Title
  
  Neuroscience Letters 438
  
  Pages: 54-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Changes in visual fields and lateral geniculate nucleus in monkey laser-induced high intraocular pressure model.2008
- Author(s)
  Sasaoka M., Nakamura K., Shimazawa M., Ito Y., Araie M., Hara H.
- Journal Title
  
  Exp. Eye Res. 86
  
  Pages: 770-782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] Imaging mouse retinal ganglion cells and their loss in vivo by a fundus camera in the normal and ischemia-reperfusion model.2008
- Author(s)
  Murata H, Aihara M, Chen YN, Ota T, Numaga J, Araie M.
- Journal Title
  
  Invest Opthamol Vis Sci 49
  
  Pages: 5546-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Long-term Effects of Latanoprost Monotherapy on Intraocular Pressure in Japanese Glaucoma Patients2008
- Author(s)
  K. KASHIWAGI, T TSUMYEA, S TSUKAHARA
- Journal Title
  
  J Glaucoma 17
  
  Pages: 662-666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Involvement of ER stress in retinal cell death2007
- Author(s)
  Shimazawa M, Inokuchi Y, Ito Y, Murata H, Aihara M, Miura M, Araie M and Hara H
- Journal Title
  
  Mol Vis 13
  
  Pages: 578-587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Neuroprotective effect of erythropoietin and role of metallothionein-1 and -2 permanent focal cerebral ischemia.2007
- Author(s)
  Wakida K, Shimazawa M, Hozumi I, Sato M, NagaseH, Inuzuka T, Hara H.
- Journal Title
  
  Neuroscience 148
  
  Pages: 105-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Effects of beta-adrenergic receptor antagonists on oxidative stress in purified rat retinal ganglion cells2007
- Author(s)
  Yu ZK, Chen YN, Aihara M, Mao W, Uchida S, Araie M
- Journal Title
  
  Mol Vis 13
  
  Pages: 833-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Neuroprotective effect of erythropoietin and role of metallothionein-1 and-2 permanent focal cerebral ischemia.2007
- Author(s)
  Wakida K, Shimazawa M, Hozumi I, Sato M, NagaseH, Inuzuka T, Hara H
- Journal Title
  
  Neuroscience 148
  
  Pages: 105-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390151
[Journal Article] Hypoxia-lnduced Retinal Ganglion Cell Death and the Neuroprotective Effects of Beta-adrenergic Antagonists2007
- Author(s)
  Yi-Ning Chen, Hideyuki Yamada, Wei Mao, Shigemi Matsuyama, Makoto Aihara, Makoto Araie.
- Journal Title
  
  Brain Res 7
  
  Pages: 28-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Involvement of double-stranded RNA-dependent protein kinase in ER stress-induced retinal neuron damage2007
- Author(s)
  Shimazawa M, Ito Y, Inokuchi Y, and Hara H
- Journal Title
  
  Invest Ophthalmol Vis Sci 48
  
  Pages: 3729-3736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Morphometric evaluation of changes with time in optic disc structure and thickness of retinal nerve fibre layer in chronic ocular hypertensive monkeys.2006
- Author(s)
  Shimazawa M., Tomita G., Taniguchi T., Sasaoka M., Hara H., Kitazawa Y., Araie M.
- Journal Title
  
  Exp. Eye Res. 82
  
  Pages: 427-440
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Nerve fiber layer measurement using scanning laser polarimetry with fixed corneal compensator in normal cycnomolgus monkey eyes.2006
- Author(s)
  Shimazawa M., Taniguchi T., Sasaoka M., Hara H.
- Journal Title
  
  Ophthalmic Res. 38
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo.2006
- Author(s)
  Harada C, Nakamura K, Namekata K, Okumura A, Mitamura Y, Iizuka Y, Kashiwagi K, Yoshida K, Ohno S, Matsuzawa A, Tanaka K, Ichijo H, Harada T.
- Journal Title
  
  Am J Pathol. 168
  
  Pages: 261-269
- Data Source
  KAKENHI-PROJECT-18209053
[Journal Article] Nerve fiber layer measurement using scanning laser polarimetry with fixed corneal compensator in normal cycnomolgus monkey eyes.2006
- Author(s)
  Shimazawa M., Taniguchi T., Sasaoka M., Hara H.
- Journal Title
  
  Ophthanlmic Res. 38
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Morphometric evaluation of changes with time in optic disc structure and thickness of retinal nerve fibre layer in chronic ocular hypertensive monkeys.2006
- Author(s)
  Shimazawa M., Tomita G., Taniguchi T., Sasaoka M., Hara H., Kitazawa Y., Araie M.
- Journal Title
  
  Exp.Eye Res. 82
  
  Pages: 427-440
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Optic disc topographic parameters, measured in the normal cynomolgus monkey by confocal scanning laser tomography.2005
- Author(s)
  Taniguchi T., Shimazawa M., Araie M., Tomita G., Sasaoka M., Kitazawa Y., Hara H.
- Journal Title
  
  Br.J.Ophthalmol. 89
  
  Pages: 1058-1062
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Optic disc topographic parameters measured in the normal cynomolgus monkey by confocal scanning laser tomography.2005
- Author(s)
  Taniguchi T., Shimazawa M., Araie M., Tomita G., Sasaoka M., Kitazawa Y., Hara H.
- Journal Title
  
  Br. J. Ophthalmol. 89
  
  Pages: 1058-1062
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591848
[Journal Article] Morphological changes in the visual pathway induced by experimental glaucoma in Japanese monkeys
- Author(s)
  Ito Y., Shimazawa M., Chen Y. N., Tsuruma K., Yamashita T., Araie M. and Hara H.
- Journal Title
  
  Exp. Eye Res (in press)
- Data Source
  KAKENHI-PROJECT-19592031
[Journal Article] Involvement of Bid and caspase-2 inendoplasmic reticulum stress- andoxidative stress-induced retinalganglion cell death.
- Author(s)
  Uchibayashi R., Tsuruma K., Inokuchi Y., Shimazawa M., Hara H.
- Journal Title
  
  J. Neurosci. Res in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 網膜オルガノイドを用いた糖尿病網膜症モデルの開発2022
- Author(s)
  中村信介、稲垣賢、青山八曇、青島弘汰、大津航、舩戸道徳、嶋澤雅光、高橋一浩、原英彰
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K09936
[Presentation] ヒトiPS細胞由来血管構造を有する網膜オルガノイドの作製2021
- Author(s)
  稲垣賢、青山八曇、舩戸道徳、中村信介、嶋澤雅光、金子英雄、原英彰
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K09936
[Presentation] Molecular insights into protein aggregation of mutant Superoxide dismutase 1 in Degenerative Myelopathy.2020
- Author(s)
  S.Kimura, R.Honda, Y.O.Kamatari, Z.Kato, H.Hara, S.Maeda, H.Kamishina.
- Organizer
  American College of Veterinary Internal Medicine Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06410
[Presentation] Molecular mechanism of protein aggregation of mutant SOD1 in canine ALS-like disease.2020
- Author(s)
  S.Kimura, R.Honda, Y.O.Kamatari, Z.Kato, H.Hara, S.Maeda, H.Kamishina.
- Organizer
  61th Annual Meeting of the Japanese Society of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06410
[Presentation] アトルバスタチン誘発ゼブラフィッシュ脳内出血モデルの作製と鉄キレート剤の効果2020
- Author(s)
  中村信介、齋藤祐一、今井貴彦、郷田拓実、嶋澤雅光、西村有平、原英彰
- Organizer
  第63回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09936
[Presentation] Triterpenoid Nrf2 activator, RS9, promotes LC3-associated phagocytosis of photoreceptor outer segments without p62 induction.2020
- Author(s)
  Nakamura S, Saito Y, Yako T, Otsu W, Inoue Y, Muramatsu A, Nakagami Y, Shimazawa M and Hara H
- Organizer
  ARVO 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09936
[Presentation] オートリソソーム形成を介したαシヌクレイン蓄積におけるProgranulinの関与2019
- Author(s)
  大庭卓也、中村信介、嶋澤雅光、原英彰
- Organizer
  第92回日本薬理学会年会（大阪、3/14-16）
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] A novel Nrf2 activator RS9 protects ARPE-19 cells from oxidative stress induced by NaIO3 via autophagic pathway2018
- Author(s)
  Saito Y, Nakamura S, Shimazawa M, Hara H
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] The pathophysiological roles of vascular endothelial growth factor (VEGF) on retinal edema and nonperfusion areas in retinal vein occlusion murine model.2018
- Author(s)
  Nishinaka A, Inoue Y, Fuma S, Hida Y, Nakamura S, Shimazawa M, Hara H
- Organizer
  ARVO 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] プログラニュリン及び切断産物グラニュリンの網膜視細胞保護に関する研究2018
- Author(s)
  田中美留豊，久世祥己，中村信介，嶋澤雅光，原英彰
- Organizer
  第３回プログラニュリン研究会
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] 視細胞障害における脂肪細胞由来幹細胞の作用及び網膜静脈閉塞症におけるVEGFの役割に関する研究2018
- Author(s)
  原英彰
- Organizer
  大阪大学蛋白研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] Adiponectin is a pathological factor for intraocular angiogenesis2018
- Author(s)
  Nakamura S, Masuda T, Sakurai S, Kawakami H, Suemori S, Mochizuki K, Shimazawa M, Hara H
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] 加齢黄斑変性におけるプログラニュリンの関与2018
- Author(s)
  髙橋慶，中村信介，嶋澤雅光，原英彰
- Organizer
  第３回プログラニュリン研究会
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] 視神経細胞保護作用に関する基礎研究の現状とビルベリ―由来機能性食品の効果2018
- Author(s)
  原英彰
- Organizer
  第122回　日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] ゼブラフィッシュ網膜再生における血小板由来成長因子 (PDGF) の関与2018
- Author(s)
  山口明洋、齋藤祐一、奥吉博之、中村信介、嶋澤雅光、原英彰
- Organizer
  第38回日本眼薬理学会
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] 網膜血管新生の基礎―網膜血管新生動物モデルの確立と新規治療薬の可能性―2017
- Author(s)
  原英彰
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Invited
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] マウス網膜静脈閉塞症モデルにおける血管内皮増殖因子の発現及び局在変化2017
- Author(s)
  西中杏里、井上雄有輝、肥田禎史、嶋澤雅光、原英彰
- Organizer
  第37回日本眼薬理学会
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] Movement of retinal vessels toward the optic nerve head after increasing intraocular pressure in monkey eyes with experimental glaucoma2017
- Author(s)
  Kuroda A, Enomoto N, Ishida K, Shimazawa M, Noguchi T, Horai N, Onoe H, Hara H, Tomita G
- Organizer
  World Glaucoma Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462634
[Presentation] 脳梗塞に対する脂肪組織由来幹細胞培養上清の基礎的検討2017
- Author(s)
  原英彰、江頭裕介、岩間亨
- Organizer
  第60回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] マウス網膜発生期におけるプログラニュリンの役割2017
- Author(s)
  久世祥己、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第2回プログラニュリン研究会
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] マウス網膜発生期におけるミクログリアの関与2017
- Author(s)
  久世祥己、大内一輝、中村信介、嶋澤雅光、原英彰
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] 白内障及び緑内障周術期薬剤使用の多施設検討2017
- Author(s)
  荒木裕加、本庄恵、石田恭子、富所敦男、原岳、相原一
- Organizer
  第71回臨床眼科学会
- Data Source
  KAKENHI-PROJECT-26462634
[Presentation] LEDは動物飼育や動物実験にどう影響を及ぼすのか？2017
- Author(s)
  原英彰
- Organizer
  日本実験動物技術者協会　関西支部設立50周年記念大会
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] Astrocyte activation and retinal ganglion cell loss during retinal development in progranulin deficient mice.2017
- Author(s)
  久世祥己、鶴間一寛、溝口貴洋、嶋澤雅光、原英彰
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] ロングチューブ型緑内障チューブシャント（LTSS）手術の適応、手技、合併症対策2017
- Author(s)
  千原悦夫、石田恭子、谷戸正樹、濱中輝彦、稲谷大
- Organizer
  第71回臨床眼科学会
- Data Source
  KAKENHI-PROJECT-26462634
[Presentation] VGF overexpression mice show psychological abnormal behaviors.2016
- Author(s)
  溝口貴洋、石坂光絵、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26462694
[Presentation] Neuroprotective effects of the conditioned medium of murine and human adipose-derived stem cells on experimental stroke models.2016
- Author(s)
  Hara H
- Organizer
  9th Pan Pacific Symposium on Stem Cells and Cancer Research
- Place of Presentation
  台湾、台北
- Year and Date
  2016-05-14
- Invited
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] Pulmonary Delivery of Peptide Drug Using Surface-modified Liposomes to Improve Systemic Absorption2016
- Author(s)
  Tahara K., Murata M., Onodera R., Takeuchi H.
- Organizer
  4th Asian Symposium on Pharmaceutical Science and Technology (ASPST)
- Place of Presentation
  Shenyang, China
- Year and Date
  2016-04-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] Evaluation of bleb characteristics after trabeculectomy, Ex-Press implantation, and tube shunt surgery2016
- Author(s)
  Ishida K, Nakano Y, Ojino K, Shimazawa M, Otsuka T, Kawase K, Hara H, Yamamoto T
- Organizer
  Eupropean Glaucoma Society Congress
- Place of Presentation
  プラハ（チェコ）
- Year and Date
  2016-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462634
[Presentation] Neuroprotective effects of the conditioned-medium of murine and human adipose-derived stem cells on experimental retinal degeneration and stroke models.2016
- Author(s)
  Hara H
- Organizer
  International Conference of Neurodegenerative Diseases and Brain Injuries
- Place of Presentation
  Weifang Ciity、Shandong、China
- Year and Date
  2016-10-28
- Invited
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] サル眼実験緑内障モデルにおける眼圧上昇後の視神経乳頭周囲の血管移動2016
- Author(s)
  黒田敦美、榎本暢子、石田恭子、嶋澤雅光、野口哲郎、賀來直人、原英彰、富田剛司
- Organizer
  第27回日本緑内障学会
- Place of Presentation
  パシフィコ横浜(神奈川県、横浜市)
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26462634
[Presentation] 視神経挫滅モデルにおけるVGF nerve growth factor inducibleの神経保護作用2016
- Author(s)
  竹内寛人、中野志迪、射和寛、久世祥己、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第36回日本眼薬理学会
- Place of Presentation
  東京
- Year and Date
  2016-09-10
- Data Source
  KAKENHI-PROJECT-26462694
[Presentation] マウス網膜再生におけるプログラニュリンの機能解析2016
- Author(s)
  久世祥己　鶴間一寛　嶋澤雅光　原英彰
- Organizer
  第1回プログラニュリン研究会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-16K11325
[Presentation] 新規RNA型核酸の肺局所投与を目的とした製剤化2016
- Author(s)
  中熊佑喜、小野寺理沙子、田原耕平、豊福秀一、竹内洋文
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] GPNMB 細胞外フラグメントの新規受容体探索に関する研究2015
- Author(s)
  小野陽子、髙田真史、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  岐阜
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25460103
[Presentation] リポソーム吸入製剤化を目的とした吸入特性評価に関する研究2015
- Author(s)
  宇仁田真秀、伊藤洋祐、村田光隆、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  第7回粉末吸入剤シンポジウム
- Place of Presentation
  富山県富山市
- Year and Date
  2015-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] Novel approaches for posterior segment ocular drug delivery with folate-modified liposomal formulation2015
- Author(s)
  Hayashi, T., Onodera, R., Tahara, K., Takeuchi, H.
- Organizer
  Asian Federation for Pharmaceutical Sciences (AFPS) Conference
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2015-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] Inhalation properties of water-soluble drug loaded liposomes atomized by nebulizer2015
- Author(s)
  Unida, S., Ito, Y., Onodera, R., Tahara, K., Takeuchi, H
- Organizer
  Asian Federation for Pharmaceutical Sciences (AFPS) Conference
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2015-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] 緑内障チューブシャント手術の適応2015
- Author(s)
  石田恭子. 谷戸正樹、稲谷大、千原悦夫、浜中輝彦
- Organizer
  第69回臨床眼科学会
- Place of Presentation
  名古屋国際会議場(愛知県、名古屋市）
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-26462634
[Presentation] 網膜への薬物送達を目的としたオクタアルギニン修飾リポソーム点眼製剤の設計2015
- Author(s)
  松浦由佳、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  第32回製剤と粒子設計シンポジウム
- Place of Presentation
  愛知県豊橋市
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] 脳虚血における膜貫通糖タンパク質GPNMBの役割2014
- Author(s)
  中野雄介、鈴木悠起也、高木俊範、北庄司輝、小野陽子、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25460103
[Presentation] TPGS/DSPE-PEG混合ミセルを用いた点眼製剤の設計に関する研究2014
- Author(s)
  Lin Ying, Kohei Tahara, Hirofumi Takeuchi
- Organizer
  第29回日本薬剤学会年会
- Place of Presentation
  大宮ソニックプラザ
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] Lipid emulsion as a new carrier for drug delivery to ocular posterior segment2013
- Author(s)
  Lin Ying, Kohei Tahara, Hirofumi Takeuchi
- Organizer
  The 5th Asian Arden Conference
- Place of Presentation
  愛知学院大学薬学部
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] 後眼部への薬物送達を目的とした微粒子点眼製剤の設計と評価2013
- Author(s)
  唐澤圭一、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  第30回製剤と粒子設計シンポジウム
- Place of Presentation
  岐阜都ホテル
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] キャリアーを活用する吸入・点眼投与製剤の設計研究2013
- Author(s)
  田原耕平、竹内洋文
- Organizer
  第31回物性物理化学研究会
- Place of Presentation
  京都大学薬学部講堂
- Invited
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] ネブライザーを用いたリポソーム吸入製剤に関する研究2013
- Author(s)
  伊藤洋祐、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿医療科学大学　白子キャンパス
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] 網膜疾患における小胞体ストレスの関与と新規治療戦略2012
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(招待講演)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22390321
[Presentation] 緑内障の病態解明と神経保護をターゲットとした薬物治療の現状と将来展望2012
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  第32回日本眼薬理学会
- Place of Presentation
  大津
- Year and Date
  2012-09-16
- Data Source
  KAKENHI-PROJECT-22390321
[Presentation] 網膜疾患における小胞体ストレスの関与と新規治療戦略2012
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 緑内障の病態解明と神経保護をターゲットとした薬物治療の現状と将来展望2012
- Author(s)
  嶋澤　雅光、原　英彰
- Organizer
  第32回日本眼薬理学会
- Place of Presentation
  ピアザ淡海
- Invited
- Data Source
  KAKENHI-PROJECT-23592612
[Presentation] げっ歯類バレル野に見出した新規軸索構築バレルネットの解析2012
- Author(s)
  瀬原慧祐、脇元麻有、赤穂吏映、河崎洋志
- Organizer
  第5回神経発生討論会
- Place of Presentation
  福井(招待講演)
- Data Source
  KAKENHI-PROJECT-22390321
[Presentation] 緑内障の病態解明と神経保護をターゲットとした薬物治療の現状と将来展望2012
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  第32回日本眼薬理学会
- Place of Presentation
  大津
- Invited
- Data Source
  KAKENHI-PROJECT-23592612
[Presentation] Eyedrop administration of edaravone-loaded liposomes protected against light-induces retinal damage2011
- Author(s)
  K.Hironaka, H.Shimazaki, T.Fujisawa, Y.Tozuka, K.Tsuruma, M.Shimazawa, H.Hara, H.Takeuchi
- Organizer
  38th Annual Meeting and Exposition of the Controlled Release Society
- Place of Presentation
  National Harbor, Maryland U.S.A.
- Data Source
  KAKENHI-PROJECT-21390011
[Presentation] 点眼したエダラボン封入リポソームの網膜障害に対する保護効果2011
- Author(s)
  廣中耕平, 嶌嵜博樹, 藤澤卓也, 戸塚裕一, 鶴間一寛, 嶋澤雅光, 原英彰, 竹内洋文
- Organizer
  第27回日本DDS学会
- Place of Presentation
  東京大学本郷キャンパス(東京都文京区本郷7-3-1)
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21390011
[Presentation] 点眼による網膜への薬物送達を目指した表面修飾リポソームの設計とその有用性評価2011
- Author(s)
  佐々木仁志、廣中耕平、田原耕平、戸塚裕一、竹内洋文
- Organizer
  第49回粉体に関する討論会
- Place of Presentation
  岩手県盛岡市いわて県民情報交流センター「アイーナ」8階会議室803
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-21390011
[Presentation] リポソーム点眼製剤の表面特性とその眼内挙動に関する研究2011
- Author(s)
  佐々木仁志、廣中耕平、唐澤圭一、田原耕平、戸塚裕一、竹内洋文
- Organizer
  第28回製剤と粒子設計シンポジウム
- Place of Presentation
  ホテルニューオータニ大阪・大阪市
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-21390011
[Presentation] 網膜・視神経障害に伴う視路変性およびその治療戦略2011
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  第54回日本神経化学大会
- Place of Presentation
  金沢
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 緑内障性視神経症と神経変性疾患の関連2011
- Author(s)
  嶋澤雅光、鶴間一寛、原英彰
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] Brain imaging in ocular hypertensive monkeys using PET and MRI2011
- Author(s)
  原英彰
- Organizer
  3^<rd> Ocular Diseases & Drug Discovery
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] NMDA誘発視神経障害における小胞体ストレスの関与2011
- Author(s)
  三輪彰範、伊藤保志、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] PETおよびMRIを用いた緑内障モデルサルにおける分子脳イメージング2011
- Author(s)
  原英彰、嶋澤雅光
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 一次体性感覚野における皮質2/3層細胞の新規局所軸索パターンの共通性と特異性2011
- Author(s)
  瀬原慧祐、脇元麻有、赤穂吏映、丹野香里、河崎洋志
- Organizer
  第34回日本神経科学学会
- Place of Presentation
  横浜(招待講演)
- Data Source
  KAKENHI-PROJECT-22390321
[Presentation] 眼疾患における脳内分子イメージング、大阪医科大学眼科オープンカンファレンスンファレンス2011
- Author(s)
  原英彰
- Organizer
  第127回特別講演
- Place of Presentation
  高槻
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 網膜虚血障害の発症機序解明とその治療2011
- Author(s)
  原英彰
- Organizer
  第13回Japan Glaucoma Council
- Place of Presentation
  東京
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] Brain imaging in ocular hypertensive monkeys using PET and MRI2011
- Author(s)
  原英彰
- Organizer
  3rd Ocular Diseases & Drug Discovery
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 網膜・視神経障害に伴う視路変性およびその治療戦略2011
- Author(s)
  嶋澤雅光、原英彰
- Organizer
  第54回日本神経化学大会
- Place of Presentation
  金沢、加賀
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 眼科治療を目的とした表面修飾リポソームの設計2011
- Author(s)
  塚本敏雅、廣中耕平、藤澤卓也、佐々木、仁志、田原耕平、戸塚裕一、竹内洋文
- Organizer
  第21回日本病院薬剤師会東海ブロック学術大会・平成23年度日本薬学東海支部例会
- Place of Presentation
  名古屋・ウインクあいち
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-21390011
[Presentation] 一次体性感覚野の皮質内局所回路形成におけるcadherinの機能解析2011
- Author(s)
  脇元麻有、瀬原慧祐、干場義生、丹野香里、竹市雅俊、河崎洋志
- Organizer
  第34回日本神経科学学会
- Place of Presentation
  横浜(招待講演)
- Data Source
  KAKENHI-PROJECT-22390321
[Presentation] 緑内障性視神経症と神経変性疾患の関連2011
- Author(s)
  嶋澤雅光、鶴間一寛、原英彰
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 点眼したエダラボン封入リポソームの網膜障害に対する保護効果2011
- Author(s)
  廣中耕平, 嶌嵜博樹, 藤澤卓也, 戸塚裕一, 鶴間一寛, 嶋澤雅光, 原英彰, 竹内洋文
- Organizer
  第27回日本DDS学会
- Place of Presentation
  東京大学本郷キャンパス
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21390011
[Presentation] 緑内障性視神経症と神経変性疾患の関連2011
- Author(s)
  嶋澤雅光、鶴間一寛、原英彰
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム(招待講演)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22390321
[Presentation] Brain imaging in laser-induced ocular hypertensive monkeys using PET and MRI2011
- Author(s)
  原英彰
- Organizer
  浙江大学薬学院招待講演
- Place of Presentation
  中国、杭州
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] Brain imaging in laser-induced ocular hypertensive monkeys using PET and MRI2011
- Author(s)
  原英彰
- Organizer
  浙江大学薬学院
- Place of Presentation
  中国、杭州(招待講演)
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] Fluorescence investigation of lipid emulsion for retinal delivery via eyedrops2011
- Author(s)
  英林, 田原耕平, 戸塚裕一, 唐星, 竹内洋文
- Organizer
  第21回日本病院薬剤師会東海ブロック学術大会・平成23年度日本薬学東海支部例会
- Place of Presentation
  名古屋・ウインクあいち
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-21390011
[Presentation] 眼疾患における脳内分子イメージング2011
- Author(s)
  原英彰
- Organizer
  大阪医科大学眼科オープンカンファレンス第127回特別講演
- Place of Presentation
  高槻
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 緑内障における外側膝状体と大脳皮質の分子イメージング2011
- Author(s)
  原英彰
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] Brain imaging in laser-induced ocular hypertensive monkeys using PET and MRI2011
- Author(s)
  原英彰
- Organizer
  中国薬科大学招待講演
- Place of Presentation
  中国、南京
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] Design of a liposomal ocular delivery system targeting the posterior segments of the eye2011
- Author(s)
  K.Hironaka, Y.Tozuka, K.Tahara, H.K.Tsuruma, M.Shimazawa, Hara. H., Takeuchi. H.
- Organizer
  Asian Federation for Pharmaceutical Science Conference 2011
- Place of Presentation
  Kuala Lumpur, Malaysia
- Data Source
  KAKENHI-PROJECT-21390011
[Presentation] Brain imaging in laser-induced ocular hypertensive monkeys using PET and MRI2011
- Author(s)
  原英彰
- Organizer
  中国薬科大学
- Place of Presentation
  中国、南京(招待講演)
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] Design of a liposomal ocular delivery system targeting the posterior segments of the eye Asian2011
- Author(s)
  K. Hironaka, Y. Tozuka, K. Tahara, H. K. Tsuruma, M. Shimazawa, Hara. H. Takeuchi
- Organizer
  Federation for Pharmaceutical Science Conference
- Place of Presentation
  Malaysia
- Data Source
  KAKENHI-PROJECT-21390011
[Presentation] ラット網膜神経節細胞初代培養を用いたグルタミン酸負荷下でのプロスタグランジン関連眼圧下降薬の細胞保護作用2010
- Author(s)
  山岸麗子、相原一、新家眞
- Organizer
  日本緑内障学会
- Place of Presentation
  福岡
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22390321
[Presentation] Evaluations of retina and brain imaging in an experimental model for glaucomatous monkeys2010
- Author(s)
  Hideaki Hara
- Organizer
  Asia-Pacific Joint Glaucoma Congress 2010 Taipei
- Place of Presentation
  Taipei International Convention Center(Taipei, Taiwan)
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 視神経と中枢の変化2010
- Author(s)
  原英彰
- Organizer
  第12回Japan Glaucoma Council
- Place of Presentation
  東京都
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] Involvement of P2X_7 receptors in the hypoxia-induced death of rat retinal neurons.2010
- Author(s)
  Sugiyama T, Oku H, Shibata M, Fukuhara M, Yoshida H, Ikeda T
- Organizer
  World Ophthalmology Congress
- Place of Presentation
  Berlin
- Data Source
  KAKENHI-PROJECT-22591972
[Presentation] The effect of SUN N8075 on endoplasmic reticulumstress-induced cell death in RGC-5 cells.2010
- Author(s)
  嶋澤雅光, 内林瑠美, 鶴間一寛, 原英彰
- Organizer
  ARVO 2010 Annual Meeting
- Place of Presentation
  FortLauderdale, Florida
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] Involvement ofendoplasmic reticulum stress onneuronal degeneration in the lateralgeniculate nucleus in the monkeyglaucoma model.2010
- Author(s)
  Ito Y., Shimazawa M., Inokuchi Y., Miwa A., Yamanaka H., Tsuruma K., Onoe H., Araie M., Hara H.
- Organizer
  ARVO 2010 AnnualMeeting
- Place of Presentation
  Fort Lauderdale, Florida
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] Evaluations of retina and brain imaging in an experimental model for glaucomatous monkeys.2010
- Author(s)
  Hideaki Hara
- Organizer
  Asia-Pacific Joint Glaucoma Congress 2010 Taipei
- Place of Presentation
  Taipei International Convention Center (Taipei, Taiwan)
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] 視神経と中枢の変化2010
- Author(s)
  原英彰
- Organizer
  第12回Japan Glaucoma Council
- Place of Presentation
  東京
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-21592262
[Presentation] フェレット高眼圧モデルにおける外側膝状体(LGN)の組織学的解析2010
- Author(s)
  藤代貴志、佐伯忠賜朗、新卓也、河崎洋志、相原一、新家眞
- Organizer
  日本緑内障学会
- Place of Presentation
  福岡
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22390321
[Presentation] CFP発現マウスを用いた視神経におけるレチノトピー2009
- Author(s)
  鶴我英和、村田博史、相原一、新家眞
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京都
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-18209053
[Presentation] In vitro およびin vivo 網膜神経節細胞死に対する新規カルパイン阻害剤 SNJ-1945 の作用2009
- Author(s)
  嶋澤雅光、末森晋典、井口勇太、松永望、中島佳美、岡隆之、山本哲也、原英彰
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 網膜神経節細胞死に対する SUN N8075 の保護作用2009
- Author(s)
  内林瑠美、嶋澤雅光、鶴間一寛、原英彰
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 網膜神経節細胞死におけるBid およびCaspase 2 の関与2009
- Author(s)
  内林瑠美、井口勇太、嶋澤雅光、鶴間一寛、原英彰
- Organizer
  第116 回日本薬理学会近畿部会
- Place of Presentation
  大津
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] マウス正常眼における網膜神経節細胞の減少率2009
- Author(s)
  村田博史、相原-、新家眞
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京都
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-18209053
[Presentation] Protectiveeffect of SUN N8075 on endoplasmicreticulum stress-induced cell death in SH-SY5Y cells.2008
- Author(s)
  嶋澤雅光, 原英彰
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] CFP発現マウスを用いた眼圧依存性網膜神経節細胞障害の評価2008
- Author(s)
  鶴我英和、村田博史、相原一、新家眞
- Organizer
  第112回日本眼科学会総会
- Place of Presentation
  横浜市
- Year and Date
  2008-04-18
- Data Source
  KAKENHI-PROJECT-18209053
[Presentation] 小胞体ストレス誘発網膜神経節細胞死に対するSUN N8075 の作用2008
- Author(s)
  嶋澤雅光、内林瑠美、原英彰
- Organizer
  第28回日本眼薬理学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20592082
[Presentation] 網膜障害誘発外側膝状体(LGN)の形態的・経時的変化2008
- Author(s)
  伊藤保志、嶋澤雅光、陳逸寧、山嶋哲盛、新家眞、原英彰
- Organizer
  第12回視覚科学フォーラム
- Place of Presentation
  豊中
- Data Source
  KAKENHI-PROJECT-19592031
[Presentation] フラボノイドの網膜神経節細胞保護効果2008
- Author(s)
  毛い、佐伯忠志朗、陳逸寧、相原一、新家眞
- Organizer
  第112回日本眼科学会総会
- Place of Presentation
  横浜市
- Year and Date
  2008-04-18
- Data Source
  KAKENHI-PROJECT-18209053
[Presentation] 網膜細胞死における小胞体誘導シャペロンの関与2007
- Author(s)
  井口勇太、嶋澤雅光、中島佳美、工藤喬、今泉和則、原英彰
- Organizer
  第80 回日本薬理学会年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18209053
[Presentation] Involvement of endoplasmic reticulum stress in retinal cell death2007
- Author(s)
  Suemori S, Shimazawa M, Yamamoto T, Hara H
- Organizer
  The ARVO Annual Meeting
- Place of Presentation
  Fort Lauderdale, Florida
- Data Source
  KAKENHI-PROJECT-18209053
[Presentation] pitavastatin(NK104)のラット網膜神経節細胞保護効果2006
- Author(s)
  毛蔚, 陳逸寧, 相原一, 新家眞. Et.al.
- Organizer
  第26回眼薬理学会
- Place of Presentation
  福井
- Data Source
  KAKENHI-PROJECT-18209053
[Presentation] 虚血再灌流モデルを用いた生体内網膜神経節細胞の経時的変化の評価2006
- Author(s)
  村田博史, 陳逸寧, 太田貴史, 相原一, 新家眞
- Organizer
  第17回日本緑内障学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-18209053
[Presentation] pitavastatin のラット網膜神経節細胞保護効果2006
- Author(s)
  毛蔚, 陳逸寧, 相原一, 新家眞. Et.al.
- Organizer
  Ophthalmoneuroprotection
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18209053
[Presentation] 膜貫通糖タンパク質GPNMBは変異TDP-43誘発運動神経細胞死を抑制する
- Author(s)
  長原悠樹、大内一輝、小野陽子、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  愛知・名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460103
[Presentation] ネブライザーを用いた薬物封入リポソーム吸入製剤に関する研究
- Author(s)
  伊藤洋佑、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶応義塾大学　芝共立キャンパス
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] 非侵襲的な投与方法を可能とする微粒子DDS 製剤の開発
- Author(s)
  田原耕平
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮ソニックシティビル
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] Extracellular fragment of GPNMB enhances memory and learning ability by increasing AMPA receptor subunit GluA1 protein level in mouse hippocampus.
- Author(s)
  Hara H., Yoshino Y., Murata K., Tsuruma K., Oyagi A., Moriguchi S., Tanaka H., Shimazawa M. and Fukunaga K.
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town, South Africa
- Year and Date
  2014-07-13 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25460103
[Presentation] Extracellular fragment of GPNMB has protective effects via Na+, K+-ATPase against SOD1(G93A)- and serum free stress-induced cell death.
- Author(s)
  Ono Y., Tanaka H., Takata M., Tsuruma K., Shimazawa M. and Hara H.
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town, South Africa
- Year and Date
  2014-07-13 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25460103
[Presentation] 後眼部への薬物送達を目的とした葉酸修飾リポソーム点眼製剤の設計
- Author(s)
  林寿樹、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶応義塾大学　芝共立キャンパス
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] GPNMB細胞外フラグメントの新規受容体としてのNa+，K+-ATPaseの同定
- Author(s)
  小野陽子、鶴間一寛、嶋澤雅光、原英彰
- Organizer
  心血管膜輸送研究会2014
- Place of Presentation
  愛知・岡崎
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25460103
[Presentation] GPNMB resists skeletal muscle lesion in the SOD1 (G93A) Mouse Model of Amyotrophic Lateral Sclerosis.
- Author(s)
  Nagahara Y., Tanaka H., Tsuruma K., Ono Y., Noda Y., Nikawa T., Shimazawa M. and Hara H.
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town, South Africa
- Year and Date
  2014-07-13 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25460103
[Presentation] 薬物封入リポソームのネブライザーによる噴霧・吸入特性の評価
- Author(s)
  伊藤洋佑、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  第 31 回製剤と粒子設計シンポジウム
- Place of Presentation
  ホテル日航福岡
- Year and Date
  2014-10-23 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] TPGS/DSPE-PEG 混合ミセルを用いた点眼製剤の設計に関する研究
- Author(s)
  英林、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮ソニックシティビル
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] 肺疾患治療を目的とした機能性核酸封入 pH 応答性リポソームの設計
- Author(s)
  藤本真、伊藤洋佑、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2015-05-21 – 2015-05-23
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] 後眼部への薬物送達を目的とした葉酸修飾リポソーム点眼製剤の設計
- Author(s)
  林寿樹、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  第52回粉体に関する討論会
- Place of Presentation
  じばさんびる
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25293008
[Presentation] 水溶性高分子封入リポソームの吸入製剤としての特性評価に関する研究
- Author(s)
  宇仁田真秀、伊藤洋佑、小野寺理沙子、田原耕平、竹内洋文
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25293008

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HARA Hideaki 原 英彰

原 英彰 ハラ ヒデアキ

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Investigation of novel drugs for inducing retinal regenerationPrincipal Investigator

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The role of progranulin in retinal regenerationPrincipal Investigator

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Identification of glycoprotein nonmetastatic melanoma protein B (GPNMB) receptor and effect of GPNMB in higher brain functionPrincipal Investigator

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HARA Hideaki 原英彰

原英彰ハラヒデアキ