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Yasutake Yoshiaki  安武 義晃

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YASUTAKE YOSHIAKI  安武 義晃

YASUTAKE Yoshiaki  安武 義晃

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Researcher Number 20415756
Other IDs
Affiliation (Current) 2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help 2020 – 2024: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
2015: 産業技術総合研究所, 生物プロセス研究部門, 研究員
2012: 独立行政法人産業技術総合研究所, 生物プロセス研究部門, 主任研究員
2011: 独立行政法人産業技術総合研究所, 生物プロセス研究部門, 研究員
Review Section/Research Field
Principal Investigator
Bacteriology (including Mycology)
Except Principal Investigator
Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Medium-sized Section 27:Chemical engineering and related fields / Basic Section 49060:Virology-related / Applied biochemistry
Keywords
Principal Investigator
アルカロイド / 放線菌 / 構造生物学 / シトクロムP450 / オーラシン / 結晶構造 / シトクロム P450 / 抗生物質
Except Principal Investigator
シトクロムP450 / 分子コーティング … More / 構造規制電極 / P450ファミリー / 立体選択性 / 酵素反応制御 / 物質生産 / 微細孔電極 / 酸化還元制御 / ビタミンD3 / 多孔質電極 / 大腸菌 / 電解合成 / 抗ウイルス薬 / 薬剤耐性変異 / 核酸アナログ / HIV / HBV / 逆転写酵素 / バイオコンバージョン / 酵素電極 / 高感度検出系 / ビタミンD受容体 / ビタミンD水酸化酵素 / ビタミンD Less
  • Research Projects

    (5 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (7 People)
  •  Precise molecular conversion platform using electrochemically-driven enzymatic reactions and its application to middle molecule drug discovery

    • Principal Investigator
      三重 安弘
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Redox control of bacterial cells using metal porous materials

    • Principal Investigator
      三重 安弘
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 27:Chemical engineering and related fields
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Comparative structural analysis of reverse transcriptase of HIV and HBV for development of anti-HBV agents

    • Principal Investigator
      Hattori Shinichiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      National Center for Global Health and Medicine
  •  Advanced use of vitamin D hydroxylases

    • Principal Investigator
      SAKAKI TOSHIYUKI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied biochemistry
    • Research Institution
      Toyama Prefectural University
  •  Research for the utilization of strong antibiotic activity of aurachin alkaloidPrincipal Investigator

    • Principal Investigator
      YASUTAKE Yoshiaki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      National Institute of Advanced Industrial Science and Technology

All 2024 2023 2022 2021 2013 2012 Other

All Journal Article Presentation

  • [Journal Article] Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations2021

    • Author(s)
      Nakajima Shogo、Watashi Koichi、Kato Takanobu、Muramatsu Masamichi、Wakita Takaji、Tamura Noriko、Hattori Shin-ichiro、Maeda Kenji、Mitsuya Hiroaki、Yasutake Yoshiaki、Toyoda Tetsuya
    • Journal Title

      Journal of Virology

      Volume: 95 Issue: 16

    • DOI

      10.1128/jvi.02401-20

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07522, KAKENHI-PROJECT-21K15458
  • [Journal Article] Cloning and heterologous expression of the aurachin RE biosynthesis gene cluster afford a novel cytochrome P450 for quinoline N-hydroxylation2013

    • Author(s)
      北川航、尾崎太郎、西岡大樹、安武義晃、波多美弥子、西山 真、葛山智久、田村具博
    • Journal Title

      ChemBioChem

      Volume: Vol. 14(印刷中) Issue: 9 Pages: 1085-1093

    • DOI

      10.1002/cbic.201300167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790492, KAKENHI-PUBLICLY-25108728, KAKENHI-PUBLICLY-23108529
  • [Presentation] 金ナノ粒子電極によるP450酵素のレドックス制御とビタミンD3の水酸化2024

    • Author(s)
      三重安弘、見上千歳、安武義晃、松田直樹
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-22K18932
  • [Presentation] Electrochemically-driven P450 reactions to produce pharmaceutical hydroxyvitamin D32023

    • Author(s)
      三重安弘、見上千歳、安武義晃
    • Organizer
      The 23rd International Conference on Cytochrome P450
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K18932
  • [Presentation] Electrochemically boosted P450 reactions to produce pharmaceutical vitamin D32023

    • Author(s)
      三重安弘、見上千歳、安武義晃
    • Organizer
      第61回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-22K18932
  • [Presentation] 酵素反応を継続的に低環境負荷で進行させるための導電性材料2022

    • Author(s)
      三重安弘、安武義晃
    • Organizer
      第20回産総研・産技連LS-BT合同研究発表会
    • Data Source
      KAKENHI-PROJECT-22K18932
  • [Presentation] HIV/HBVキメラ逆転写酵素の構造情報を基盤とした抗HBV核酸アナログE-CFCPの作用機構の洞察2022

    • Author(s)
      安武義晃、服部真一朗、熊本浩樹、田村範子、前田賢次、満屋裕明
    • Organizer
      第30回日本抗ウイルス療法学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07522
  • [Presentation] Controlling Surface Structure of Nanoporous Gold Catalyst toward Enzymatic Production of Valuable Molecules2022

    • Author(s)
      三重安弘、見上千歳、安武義晃
    • Organizer
      第32回日本MRS年次大会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K18932
  • [Presentation] オーラシン類に強い抗菌活性を付与するシトクロムP450 RauAの構造機能解析2013

    • Author(s)
      安武義晃、北川航、西岡大樹、田村具博
    • Organizer
      物構研サイエンスフェスタ
    • Place of Presentation
      エポカルつくば(茨城県)
    • Year and Date
      2013-03-14
    • Data Source
      KAKENHI-PROJECT-23790492
  • [Presentation] 放線菌シトクロムP450の構造機能解析とその利用に向けた研究2012

    • Author(s)
      安武義晃
    • Organizer
      Sapporo Symposium on advanced protein crystallography(招待講演)
    • Place of Presentation
      北海道札幌市・北海道大学
    • Data Source
      KAKENHI-PROJECT-23790492
  • [Presentation] Intraspecies competition by antibiotics in Rhodococcuserythropolis strains2012

    • Author(s)
      北川航、安武義晃、田村具博
    • Organizer
      International Symposium on Microbial Ecology
    • Place of Presentation
      ベラセンター・コペンハーゲン(デンマーク)
    • Year and Date
      2012-08-24
    • Data Source
      KAKENHI-PROJECT-23790492
  • [Presentation] オーラシンアルカロイドに抗菌活性を付与するシトクロムP4502012

    • Author(s)
      安武義晃、北川航、西岡大樹、尾崎太郎、西山真、葛山智久、田村具博
    • Organizer
      日本農芸化学会2012年度大会
    • Place of Presentation
      京都府京都市・京都女子大学
    • Data Source
      KAKENHI-PROJECT-23790492
  • [Presentation] 、Structural and functional analysis of a novel cytochrome P450 RauA responsible for conferring antibiotic activity on aurachin alkaloid. A Joint Meeting of the Asian Crystallographic Association (AsCA)2012

    • Author(s)
      安武義晃、北川航、西岡大樹、尾崎太郎、西山真、葛山智久、田村具博
    • Organizer
      Society of Crystallographers in Australia and New Zealand (SCANZ) and the BRAGG Symposium
    • Place of Presentation
      アデレードコンベンションセンター(オーストラリア)
    • Year and Date
      2012-12-04
    • Data Source
      KAKENHI-PROJECT-23790492
  • [Presentation] CYP105A1変異体発現Rhodococcus属放線菌を用いたビタミンD水酸化体の生産

    • Author(s)
      余語祐哉、安田佳織、林恵子、杉本宏、滝田禎亮、保川清、安武義晃、田村具博、太田美穂、鎌倉昌樹、生城真一、榊利之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25292062
  • [Presentation] Microbial production of hydroxylated metabolites of vitamin D

    • Author(s)
      Kaori Yasuda, Yuya Yogo, Keiko Hayashi, Mariko Endo, Masaki Kamakura, Miho Ohta, Yoshiaki Yasutake, Tomohiro Tamura, Shinichi Ikushiro and Toshiyuki Sakaki
    • Organizer
      12th International Symposium on cytochrome P450 Biodiversity and Biotechnology
    • Place of Presentation
      京都
    • Year and Date
      2014-09-24 – 2014-09-28
    • Data Source
      KAKENHI-PROJECT-25292062
  • [Presentation] Structural and functional analysis of a novel cytochrome P450 RauA responsible for conferring antibiotic activity on aurachin alkaloid

    • Author(s)
      安武義晃、北川航、西岡大樹、尾崎太郎、西山 真、葛山智久、田村具博
    • Organizer
      A Joint Meeting of the Asian Crystallographic Association (AsCA), Society of Crystallographers in Australia and New Zealand (SCANZ) and the BRAGG Symposium
    • Place of Presentation
      アデレード
    • Data Source
      KAKENHI-PROJECT-23790492
  • [Presentation] CYP105A1三重変異体発現Rhodococcus属放線菌を用いたビタミンD水酸化体の生産

    • Author(s)
      余語祐哉、安田佳織、真野寛生、林恵子、杉本宏、滝田禎亮、保川清、安武義晃、田村具博、太田美穂、鎌倉昌樹、生城真一、榊利之
    • Organizer
      農芸化学会2015年度大会
    • Place of Presentation
      岡山
    • Year and Date
      2015-03-26 – 2015-03-29
    • Data Source
      KAKENHI-PROJECT-25292062
  • [Presentation] Hot spot on the ferredoxin-binding site of cytochrome P450 for changing overall conformational states

    • Author(s)
      安武義晃、西岡大樹、田村具博
    • Organizer
      11th International Symposium on Cytochrome P450 Biodiversity and Biotechnology
    • Place of Presentation
      トリノ
    • Data Source
      KAKENHI-PROJECT-23790492
  • [Presentation] Intraspecies competition by antibiotics in Rhodococcus erythropolis strains

    • Author(s)
      北川航、安武義晃、田村具博
    • Organizer
      International Symposium on Microbial Ecology
    • Place of Presentation
      コペンハーゲン
    • Data Source
      KAKENHI-PROJECT-23790492
  • [Presentation] オーラシン類に強い抗菌活性を付与するシトクロムP450 RauAの構造機能解析

    • Author(s)
      安武義晃、北川航、西岡大樹、田村具博
    • Organizer
      物構研サイエンスフェスタ(PFシンポジウム)
    • Place of Presentation
      つくば市
    • Data Source
      KAKENHI-PROJECT-23790492
  • 1.  三重 安弘 (00415746)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 2.  SAKAKI TOSHIYUKI (70293909)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  KANO KENJI (10152828)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  IKUSHIRO SHINICHI (50244679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  TAMURA TOMOHIRO (30357488)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  Hattori Shinichiro (60709484)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  辻野 博文 (10707144)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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