Yamaoka Kunihiro 山岡邦宏

… Alternative Names

YAMAOKA Kunihiro 山岡邦宏

Less

Researcher Number	20425317
Other IDs	https://orcid.org/0000-0001-8858-9435
Affiliation (Current)	2024: 北里大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2024: 北里大学, 医学部, 教授 2018 – 2022: 北里大学, 医学部, 教授 2010 – 2011: 産業医科大学, 医学部, 講師 2007 – 2009: University of Occupational and Environmental Health, Japan, School of Medicine, assistant professor 2006: 産業医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / 膠原病・アレルギー・感染症内科学 Except Principal Investigator 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator 単球 / MS4A4A / 関節リウマチ / 樹状細胞 / マクロファージ / フローサイトメトリー / ノックアウトマウス / 末梢血 / 滑膜細胞 / 単球系細胞 … More / 共刺激分子 / Jak阻害剤 / Jak3 / 滑膜線維芽細胞 / 骨代謝 / サイトカイン / リウマチ学 / Stat5 / 自己免疫疾患 / Stat6 / 臨床免疫学 … More Except Principal Investigator transcriptional regulation / transcriptional factor / inflammatory cytokine / IL1 beta / 遺伝子発現調節 / 転写因子 / 炎症性サイトカイン / IL-1β Less

自然免疫細胞に発現するMS4A4Aの自己免疫疾患病態との関連と臨床応用Principal Investigator
- Principal Investigator
  
  山岡邦宏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kitasato University
関節リウマチ病態におけるMS4A4Aの機能解明と新規治療法に向けた基盤情報の確立Principal Investigator
- Principal Investigator
  
  山岡邦宏
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kitasato University
Function and clinical application of MS4A4A involved in pathology of rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  Yamaoka Kunihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kitasato University
Development of novel medication strategy and drug efficacy on monocyte lineage cells of a JAK3 inhibitor in rheumatoid arthritis patientsPrincipal Investigator
- Principal Investigator
  
  YAMAOKA Kunihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Function of Stat5 in myeloid lineage cells : A explorative research to control autoimmune diseasePrincipal Investigator
- Principal Investigator
  
  YAMAOKA Kunihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Therapeutic strategy for inflammatory diseases by a novel negative regulatory transcriptional factor of inflammatory cytokines
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2023 2022 2021 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 関節リウマチ治療実践バイブル改訂第2版2021
- Author(s)
  山岡邦宏
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21K08446
[Book] 関節リウマチ治療実践バイブル改訂第2版2021
- Author(s)
  有沼良幸, 山岡邦宏
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21K08446
[Book] 関節リウマチ薬はこう使う！2021
- Author(s)
  山岡邦宏
- Publisher
  月刊薬事じほう
- Data Source
  KAKENHI-PROJECT-21K08446
[Book] 今日の治療指針2022年版2021
- Author(s)
  山岡邦宏
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21K08446
[Book] 内科学2021
- Author(s)
  山岡邦宏
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-21K08446
[Book] ファーマナビゲーター,リウマチ～生物学的製剤編単独投与、抗リウマチ薬(MTX)の併用との使い分けのコツありますか2010
- Author(s)
  山岡邦宏, 田中良哉
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Incidence and risk factors for herpes zoster in patients with rheumatoid arthritis receiving upadacitinib: a pooled analysis of six phase III clinical trials.2022
- Author(s)
  Winthrop KL., Nash P., Yamaoka K., Mysler E., Khan N., Camp K L., Song Y., Suboticki J L., Curtis J R .
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 81(2): Issue: 2 Pages: 206-213
- DOI
  10.1136/annrheumdis-2021-220822
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08446
[Journal Article] Clinical management of herpes zoster in patients with rheumatoid arthritis and psoriatic arthritis receiving tofacitinib treatment.2022
- Author(s)
  Winthrop KL., Curtis JR., Yamaoka K., Lee EB. ,Hirose T., Rivas JL., Kwok K., Burmester GR.
- Journal Title
  
  Rheumatology and Therapy
  
  Volume: 9(1) Issue: 1 Pages: 243-263
- DOI
  10.1007/s40744-021-00390-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08446
[Journal Article] Efficacy and safety of upadacitinib over 84 weeks in Japanese patients with rheumatoid arthritis (SELECT-SUNRISE).2021
- Author(s)
  Kameda H, Takeuchi T, Yamaoka K, Oribe M, Kawano M, Yokoyama M, Pangan A, Konishi Y, Meerwein S,Tanaka Y.
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 23(1):9 Issue: 1 Pages: 1-10
- DOI
  10.1186/s13075-020-02387-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08446
[Journal Article] Thymus variants on imaging in patients with rheumatoid arthritis-Clinical and immunological significance.2021
- Author(s)
  Murata O., Suzuki K., Takeuchi T., Sugiura H., Kondo Y., Takeshita M., Koga K., Takiguchi M., Kassai Y., Yasuoka H., Yamaoka K., Morita R., Yoshimura A.
- Journal Title
  
  Rheumatology(Oxford)
  
  Volume: 60(12) Issue: 12 Pages: 5595-5600
- DOI
  10.1093/rheumatology/keab164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08446
[Journal Article] A Case of Anti-MDA5 Antibody-positive Dermatomyositis Developing Reversible Cerebral Vasospasm Syndrome Successfully Treated by Multi-Immunosuppressant Combination Including Mycophenolate Mofetil.2021
- Author(s)
  Muramatsu T, Tono T, Kanayama Y, Hasegawa Y, Kondo J, Hoshiyama T, Wada T, Arinuma Y, Tanaka S, Yamaoka K.
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: 5 (1) Issue: 1 Pages: 69-75
- DOI
  10.1080/24725625.2020.1810398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08446
[Journal Article] Janus kinase (JAK)阻害薬tofacitinibの作用機序と自己免疫疾患治療薬への可能性2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: 47 Pages: 97-100
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Anti-rheumatic effect of JAK inhibitors2012
- Author(s)
  Yamaoka K., Maeshima K., Kubo S., Sonomoto K., Tanaka Y.
- Journal Title
  
  Jpn J Clin.Immunol
  
  Volume: 35 Pages: 112-117
- NAID
  10030573749
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Effect of COX-2 selective inhibitor celecoxib on upper gastrointestinal symptoms in patients with rheumatoid arthritis-Evaluation of switch from non-steroidal anti-inflammatory drugs2012
- Author(s)
  Hirata S., Saito K., Sawamukai N., Nakano K., Yamaoka K., Tanaka Y.
- Journal Title
  
  Kyushu J Rheumatol
  
  Volume: 32 Pages: 17-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] JAK-Statシグナル伝達経路を介したIL-10の産生制御2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57 Pages: 470-474
- NAID
  40019309840
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Churg-Strauss syndrome complicated by bilateral central retinal artery occlusion2012
- Author(s)
  Katsuyama T., Saito K., Yamaoka K, Hirata S., Tsujimura S., Nawata M., Tanaka Y.
- Journal Title
  
  Kyushu J Rheumatol
  
  Volume: 32 Pages: 52-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] JAK阻害薬2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  医薬ジャーナル
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Mesenchymal stem cells : A new treatment tool for rheumatoid arthritis2012
- Author(s)
  Sonomoto K., Yamaoka K., Tanaka Y.
- Journal Title
  
  Inflammation and Regeneration Journal
  
  Volume: (In press)
- NAID
  130004482298
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Regulation of inflammation through JAK3-Stat6 pathway in dendritic cells2012
- Author(s)
  Yamaoka K, Maeshima K, Kubo S, Tanaka Y
- Journal Title
  
  Jpn J Clin Immunol
  
  Volume: 35 Pages: 62-68
- NAID
  10030465675
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] In vitro and in vivo analysis of a Jak inhibitor in rheumatoid arthritis2012
- Author(s)
  Tanaka Y, Maeshima K, Yamaoka K
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 71(Supp II)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] JAK3の発見から臨床応用まで2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  炎症と免疫
  
  Volume: 20 Pages: 268-271
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] JAK阻害薬tofacitinibの抗リウマチ作用2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  医学のあゆみ
  
  Volume: 240 Pages: 562-566
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] ヒトB細胞活性化におけるSykを介したTLR9シグナルの増幅メカニズム2012
- Author(s)
  岩田慈、山岡邦宏、新納宏昭、赤司浩一、田中良哉
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: (In press)
- NAID
  130006947788
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Involvement of Syk in pathology of systemic autoimmune disease2012
- Author(s)
  Iwata S, Yamaoka K, Tanaka Y
- Journal Title
  
  Jpn J Clin Immunol
  
  Volume: 35 Pages: 56-61
- NAID
  10030465649
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Amplification of toll-like receptor-mediated signaling through Syk in human B cell activation2012
- Author(s)
  Iwata S, Yamaoka K, Tanaka Y
- Journal Title
  
  J Allergy and Clinical Immunology
- NAID
  40019337340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] 樹状細胞におけるJAK3-Stat6を介した炎症制御機構2012
- Author(s)
  山岡邦宏、久保智史、前島圭佑、田中良哉
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57 Pages: 264-268
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] ヒト間葉系幹細胞による破骨細胞の活性制御2012
- Author(s)
  尾下浩一、山岡邦宏、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] JAK阻害薬の有用性は?2012
- Author(s)
  前島圭佑、山岡邦宏、石井宏治、田中良哉
- Journal Title
  
  内科
  
  Volume: 109 Pages: 664-666
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Anti-rheumatic effect of JAK inhibitors2012
- Author(s)
  Yamaoka K, Maeshima K, Kubo S, Sonomoto K, Tanaka Y
- Journal Title
  
  Jpn J Clin. Immunol
- NAID
  10030573749
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Marked improvement of calcinosis in adult dermatomyositis with etidronate therapy2012
- Author(s)
  Mori H., Okada Y., Yamaoka K., Tanaka Y.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 30 Pages: 114-118
- NAID
  10031168760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] JAK inhibitor : tofacitinib, a new disease modifying anti-rheumatic drug2011
- Author(s)
  Yamaoka K, Kubo S, Sonomoto K, Maeshima K, Tanaka Y
- Journal Title
  
  Inflammation and Regeneration Journal
  
  Volume: 31 Pages: 349-353
- NAID
  130004482280
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] In vitro and in vivo analysis of a Jak inhibitor in rheumatoid arthritis2011
- Author(s)
  Tanaka Y., Maeshima K., Yamaoka K.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 71
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Phenotypic Changes of Lymphocytes in Patients with Systemic Lupus Erythematosus who are in the long-term remission After B Cell Depletion Therapy with Rituximab2011
- Author(s)
  Iwata S, Yamaoka K, Tanaka Y
- Journal Title
  
  J Rheumatol
  
  Volume: 38 Pages: 633-641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Jak and Syk : Emerging their relevance to the treatment of inflammatory diseases2011
- Author(s)
  Tanaka Y, Iwata S, Yamaoka K
- Journal Title
  
  Inflammation and Regeneration Journal
  
  Volume: 31 Pages: 237-44
- NAID
  130004943791
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Human mesenchymal stem cells inhibit osteoclastogenesis through osteoprotegerin production2011
- Author(s)
  Oshita K, Yamaoka K, Tanaka Y
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63 Pages: 1658-1667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Janus kinase(JAK) inhibitors in rheumatoid arthritis2011
- Author(s)
  Yamaoka K, Tanaka Y
- Journal Title
  
  Curr Rheum Rev
  
  Volume: 7 Pages: 306-312
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Janus kinase (JAK)特異的阻害薬の効果に基づく作用機序の検討2011
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: 46 Pages: 84-88
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Pericarditis induced by prophylactic administration of isoniazid in a patient with rheumatoid arthritis2011
- Author(s)
  Kubo S, Yamaoka K, Saito K, Tanaka Y
- Journal Title
  
  Joint Bone spine
  
  Volume: 78 Pages: 99-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Efficacy of combination therapy of anti-TNF-α antibody infliximab and methotrexate in refractory entero-Behcet's disease2011
- Author(s)
  Iwata S, Yamaoka K, Tanaka Y
- Journal Title
  
  Mod Rheumatol
  
  Volume: 21 Pages: 184-191
- NAID
  10029361883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Human mesenchymal stem cells inhibit osteoclastogenesis through osteoprotegerin production.2011
- Author(s)
  Oshita K., Yamaoka K., et al.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Janus kinase (JAK) inhibitors in rheumatoid arthritis2011
- Author(s)
  Yamaoka K., Tanaka Y.
- Journal Title
  
  Curr Rheum Rev
  
  Volume: 7 Pages: 306-312
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Cytokine-mediated signals as targets for treatment of rheumatoid arthritis : a JAK inhibitor in vitro and in vivo2011
- Author(s)
  Tanaka Y, Yamaoka K
- Journal Title
  
  Int J Clin Rheumatol
  
  Volume: 6 Pages: 439-4444
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Dopamine induces IL-6-dependent IL-17 production via D1-like receptor on CD4 naive T-cells and a D1-like receptor antagonist SCH-23390 inhibits cartilage destruction in a human rheumatoid arthritis/SCID mouse chimera model2011
- Author(s)
  Nakano K, Yamaoka K, Tanaka Y
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 3745-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Dopamine induces IL-6-dependent IL-17 production via D1-like receptor on CD4 naive T-ceIts and a Dl-like receptor antagonist SCH-23390 inhibits cartilage destruction in a human rheumatoid arthritis/SCID mouse chimera model.2011
- Author(s)
  Nakano K, Yamaoka K., et al.
- Journal Title
  
  J Immunol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] 細胞内シグナル分子を標的とした治療:JAK2011
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  最新医学
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] A JAK inhibitor tofacitinib regulates synovitis through inhibition of IFN-・and IL-17 production by human CD4+T cells2011
- Author(s)
  Maeshima K, Yamaoka K, Tanaka Y
- Journal Title
  
  Arthritis Rheum
  
  Volume: (In press) Issue: 6 Pages: 1790-1798
- DOI
  10.1002/art.34329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Involvement of mast cells in systemic sclerosis2010
- Author(s)
  Yukawa S, Yamaoka K, Tanaka Y
- Journal Title
  
  Jpn. J. Clin. Immunol
  
  Volume: 33 Pages: 81-86
- NAID
  10027753435
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] C5a promotes migration, proliferation, and vessel-formation in endothelial cells2010
- Author(s)
  Kurihara R, Yamaoka K, Tanaka Y
- Journal Title
  
  Inflamm Res
  
  Volume: 59 Pages: 659-666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] シグナル伝達分子を標的とした関節リウマチ治療:新規抗リウマチ薬の可能性2009
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  医学のあゆみ 230
  
  Pages: 786-791
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Jak阻害の特異性と関節リウマチに対する治療効果2009
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  感染・炎症・免疫 39
  
  Pages: 63-65
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Jak inhibitor ; possibility and mechanism as a new disease modifying anti-rheumatic drug2009
- Author(s)
  Yamaoka K, Tanaka Y
- Journal Title
  
  Jpn J Clin Immunol
  
  Volume: 32 Pages: 85-91
- NAID
  10024962052
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Jak3阻害2009
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  炎症と免疫 17
  
  Pages: 524-529
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] RAにおけるチロシンキナーゼ阻害薬の役割2009
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  Frontiers in Rheuma& Clinlmmunol 3
  
  Pages: 32-36
- NAID
  40017004423
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Amplification of toll-like receptor-mediated signaling through Syk in human B cell activation
- Author(s)
  Iwata S., Yamaoka K, Niiro H., Nakano K., Wang SP., Akashi K., Tanaka Y.
- Journal Title
  
  J Allergy and Clinical Immunology
  
  Volume: (In press)
- NAID
  40019337340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] expression in peripheral blood monocytes of patients with rheumatoid arthritis.2023
- Author(s)
  村松匠、奥健志、松枝佑、近藤惇一、長谷川靖浩、山岡邦宏.
- Organizer
  第67回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] Treatment goals, targets and guidelines in lupus nephritis2021
- Author(s)
  Yamaoka K
- Organizer
  23nd Asia-Pacific League of Associations for Rhuematology Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] JAKと生物製剤による関節破壊治療の最前線　Front-line treatments forthe joint destructive disease; JAK inhibitors andbiologics2021
- Author(s)
  山岡邦宏.
- Organizer
  第42回炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] Considering the efficacy of tofacitinibthrough recent information on safety.2021
- Author(s)
  Yamaoka K
- Organizer
  23nd Asia-Pacific League of Associations for Rhuematology Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] 関節リウマチの新規治療2021
- Author(s)
  山岡邦宏
- Organizer
  第36回日本臨床リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] 乾癬性関節炎患者におけるウパダシニブの安全性：全体集団及び日本人集団における臨床試験併合解析の結果（Safety Profile of Upadacitinib in Psoriatic Arthritis (PsA): Findings in the Global Population and Japanese Subgroup From a Pooled Analysis of 2 Phase 3 Clinical Trials.）2021
- Author(s)
  Yamaoka K., Burmester GR., Winthrop K., Nash P. Goupille P., Azevedo VF., Salvarani C., Mccaskill RM., Liu J, Pierre-Louis BJ., Anderson JK., Ruderman EM.
- Organizer
  第65回日本リウマチ学会総会・学術集会.
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] JAK-Statシグナル伝達経路阻害による抗炎症作用2011
- Author(s)
  山岡邦宏、田中良哉
- Organizer
  第29回日本骨代謝学会
- Place of Presentation
  大阪国際会議場(大阪)(招待講演)
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 次世代低分子化合物を用いた治療-JAK阻害薬2011
- Author(s)
  山岡邦宏
- Organizer
  第55回日本リウマチ学会総会Next decadeシンポジウム
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] JAK-STATシグナル伝達経路阻害による炎症抑制作用2011
- Author(s)
  山岡邦宏、前島圭佑、久保智史、園本格士郎、湯川宗之助、岩田慈、田中伸哉、宮原寿明、田中良哉
- Organizer
  第32回日本炎症再生医学会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] A JAK inhibitor, tofacitinib reduces IL-6 and matrix metalloproteinase-3 production in rheumatoid arthritis with suppressed cartilage destruction2011
- Author(s)
  Yamaoka K., Kubo S., Sonomoto K., Maeshima K., Tanaka Y.
- Organizer
  1st Bio-Rheumatology International Congress
- Place of Presentation
  ヒルトン東京ベイホテル(東京)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] IL-10 production induced by LPS is negatively regulated by Stat6 in dendritic cells2011
- Author(s)
  Yamaoka K
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] リウマチ性疾患の治療の進歩-低分子化合物の可能性と作用機序2011
- Author(s)
  山岡邦宏、田中良哉
- Organizer
  第39回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル(東京)(招待講演)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] JAK-Statシグナル伝達経路阻害による抗炎症作用2011
- Author(s)
  山岡邦宏
- Organizer
  第29回日本骨代謝学会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] JAK-STATシグナル伝達経路阻害による炎症抑制作用2011
- Author(s)
  山岡邦宏
- Organizer
  第32回日本炎症再生医学会
- Place of Presentation
  第32回日本炎症再生医学会京都国際会館(京都)
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] リウマチ性疾患の治療の進歩-低分子化合物の可能性と作用機序2011
- Author(s)
  山岡邦宏
- Organizer
  合同シンポジウム1第39回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] JAK阻害薬による関節リウマチ治療とその作用機序2011
- Author(s)
  山岡邦宏
- Organizer
  第39回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 次世代低分子化合物を用いた治療-JAK阻害薬2011
- Author(s)
  山岡邦宏、田中良哉
- Organizer
  第55回日本リウマチ学会総会学術集会
- Place of Presentation
  神戸ポートピアホテル(神戸)(招待講演)
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Tofacitinib reduces Interleukin-6 and Matrix Metalloproteinase-3 production and inhibits cartilage destruction in rheumatoid arthritis2011
- Author(s)
  Yamaoka K., Kubo S., Maeshima K., Sonomoto K., Nakano K., Sawamukai N., Iwata S., Nawata M., Saito K., Tanaka Y.
- Organizer
  American college of Rheumatology
- Place of Presentation
  McCormick Place West(シカゴ)
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] JAK阻害薬投与による関節リウマチ患者由来CD4+T細胞のIL-17産生抑制作用2011
- Author(s)
  山岡邦宏
- Organizer
  第55回日本リウマチ学会総会学術集会
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 低分子化合物を用いた治療の進歩2011
- Author(s)
  山岡邦宏
- Organizer
  シンポジウム19;関節リウマチの診療の革新的進歩第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  グランドプリンスホテル新高輪(東京)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Tofacitinib reduces Interleukin-6 and Matrix Metalloproteinase-3 production and inhibits cartilage destruction in rheumatoid arthritis2011
- Author(s)
  Yamaoka K
- Organizer
  American college of Rheumatology McCormick Place West
- Place of Presentation
  シカゴ
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 樹状細胞Stat6のIL-10産生制御機構2011
- Author(s)
  山岡邦宏
- Organizer
  第39回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 低分子化合物を用いた治療の進歩2011
- Author(s)
  山岡邦宏、田中良哉
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  グランドプリンスホテル新高輪(東京)(招待講演)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Stat6 in dendritic cells is involved in inflammation by negatively regulating IL-10 production2010
- Author(s)
  Yamaoka K
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Jak阻害薬の抗リウマチ薬としての可能性とその作用機序2010
- Author(s)
  山岡邦宏
- Organizer
  第75回日本インターフェロンサイトカイン学会
- Place of Presentation
  北九州国際会議場(北九州)
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] JAKインヒビター2010
- Author(s)
  山岡邦宏
- Organizer
  第31回日本炎症再生医学会
- Place of Presentation
  シンポジウム京王プラザホテル(東京)
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Jak阻害薬(CP-690, 550)による臨床的効果とMMP-3低下作用2010
- Author(s)
  山岡邦宏
- Organizer
  第54回日本リウマチ学会総会学術集会
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Involvement of Stat6 in inflammation by negatively regulating IL-10production2010
- Author(s)
  Yamaoka K
- Organizer
  第11回欧州リウマチ学会
- Place of Presentation
  Fiera di Roma(ローマ)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 樹状細胞のJak3-Stat6によるIL-10産生制御を介した炎症性疾患制御2010
- Author(s)
  山岡邦宏
- Organizer
  第54回日本リウマチ学会総会学術集会
- Place of Presentation
  神戸(神戸ポートピアホテル)
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Jak阻害薬の抗リウマチ薬としての可能性とその作用機序2010
- Author(s)
  山岡邦宏
- Organizer
  第54回日本リウマチ学会総会学術集会
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 樹状細胞のJak3-Stat6によるIL-10産生制御を介した炎症性疾患制御2010
- Author(s)
  山岡邦宏
- Organizer
  第54回日本リウマチ学会総会学術集会
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] JAK-STATシグナル伝達経路阻害による炎症抑制作用2010
- Author(s)
  山岡邦宏
- Organizer
  第75回日本インターフェロンサイトカイン学会
- Place of Presentation
  北九州国際会議場(北九州)
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Role of Jak3-Stat6 and effect of Jak inhibitor on dendritic cells and itsinvolvement in rheumatoid arthritis2009
- Author(s)
  山岡邦宏, 他
- Organizer
  日本臨床免疫学会
- Place of Presentation
  東京(東京ステーションコンファレンス)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 関節リウマチに対するJak阻害剤の樹状細胞を介した効果2009
- Author(s)
  山岡邦宏
- Organizer
  第53回日本リウマチ学会総会学術集会
- Place of Presentation
  グランドプリンスホテル新高輪(東京)
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Role of Jak3-Stat6 in dendritic cells and its involvement in inflammation2009
- Author(s)
  山岡邦宏, 他
- Organizer
  日本免疫学会
- Place of Presentation
  大阪(大阪国際会議場)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Inhibition of Jak3-Stat6 pathway leading to an anti-inflammatory process in rheumatoid arthritis2009
- Author(s)
  山岡邦宏, 他
- Organizer
  アメリカリウマチ学会
- Place of Presentation
  フィラデルフィア、USA(Pennsylvania Convention Center)
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Role of Jak3-Stat6 and effect of Jak inhibitor on dendritic cells and its involvement in rheumatoid arthritis2009
- Author(s)
  Yamaoka K
- Organizer
  第37回日本臨床免疫学会
- Place of Presentation
  東京ステーションコンファレンス(東京)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Role of Jak3-Stat6 in dendritic cells and its involvement in inflammation2009
- Author(s)
  Yamaoka K
- Organizer
  第39回日本免疫学会総会学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 関節リウマチに対するJak阻害剤の樹状細胞を介した効果2009
- Author(s)
  山岡邦宏, 他
- Organizer
  日本リウマチ学会
- Place of Presentation
  東京(グランドプリンスホテル新高輪)
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Jak3-Stat6 in dendritic cells ; involvement in the pathological condition of RA2009
- Author(s)
  Yamaoka K
- Organizer
  第74回日本インターフェロンサイトカイン学会
- Place of Presentation
  京都大学(京都)
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Jak3-Stat6 in dendritic cells ; involvement in the pathological condition of RA2009
- Author(s)
  山岡邦宏, 他
- Organizer
  日本インターフェロン・サイトカイン学会
- Place of Presentation
  京都(日芝蘭会館)
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Inhibition of Jak3-Stat6 pathway leading to an anti-inflammatory process in rheumatoid arthritis2009
- Author(s)
  Yamaoka K
- Organizer
  American college of Rheumatology Pennsylvania convention center
- Place of Presentation
  フィラデルフィア
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-21591275

1. TANAKA Yoshiya (30248562)

# of Collaborated Projects: 2 results

# of Collaborated Products: 49 results
2. 松枝佑 (00623208)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. SAITO Kazuyoshi (30279327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 竹内勤 (50179610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 吉本桂子 (20383292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 有沼良幸 (30527437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 奥健志 (70544295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamaoka Kunihiro 山岡 邦宏

YAMAOKA Kunihiro 山岡 邦宏

Research Projects

Research Products

Co-Researchers

自然免疫細胞に発現するMS4A4Aの自己免疫疾患病態との関連と臨床応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

関節リウマチ病態におけるMS4A4Aの機能解明と新規治療法に向けた基盤情報の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Function and clinical application of MS4A4A involved in pathology of rheumatoid arthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel medication strategy and drug efficacy on monocyte lineage cells of a JAK3 inhibitor in rheumatoid arthritis patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function of Stat5 in myeloid lineage cells : A explorative research to control autoimmune diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic strategy for inflammatory diseases by a novel negative regulatory transcriptional factor of inflammatory cytokines

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 関節リウマチ治療 実践バイブル 改訂第2版2021

Author(s)

Publisher

Data Source

[Book] 関節リウマチ治療 実践バイブル 改訂第2版2021

Author(s)

Publisher

Data Source

[Book] 関節リウマチ薬はこう使う！2021

Author(s)

Publisher

Data Source

[Book] 今日の治療指針2022年版2021

Author(s)

Publisher

Data Source

[Book] 内科学2021

Author(s)

Publisher

Data Source

[Book] ファーマナビゲーター,リウマチ～生物学的製剤編単独投与、抗リウマチ薬(MTX)の併用との使い分けのコツありますか2010

Author(s)

Publisher

Data Source

[Journal Article] Incidence and risk factors for herpes zoster in patients with rheumatoid arthritis receiving upadacitinib: a pooled analysis of six phase III clinical trials.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical management of herpes zoster in patients with rheumatoid arthritis and psoriatic arthritis receiving tofacitinib treatment.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy and safety of upadacitinib over 84 weeks in Japanese patients with rheumatoid arthritis (SELECT-SUNRISE).2021

Author(s)

Journal Title

DOI

Data Source

Yamaoka Kunihiro 山岡邦宏

YAMAOKA Kunihiro 山岡邦宏

[Book] 関節リウマチ治療実践バイブル改訂第2版2021

[Book] 関節リウマチ治療実践バイブル改訂第2版2021