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Kiniwa Yukiko  木庭 幸子

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KINIWA Yukiko  木庭 幸子

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Researcher Number 20436893
Other IDs
Affiliation (Current) 2025: 信州大学, 学術研究院医学系, 准教授
Affiliation (based on the past Project Information) *help 2023: 信州大学, 学術研究院医学系, 准教授
2018 – 2020: 信州大学, 学術研究院医学系, 准教授
2014 – 2017: 信州大学, 学術研究院医学系(医学部附属病院), 講師
2014 – 2015: 信州大学, 学術研究院医学系(医学部付属病院), 講師
2011 – 2013: 信州大学, 医学部附属病院, 講師
2011: 信州大学, 医学部・附属病院, 講師
2007 – 2010: Shinshu University, 医学部, 助教
Review Section/Research Field
Principal Investigator
Dermatology / Basic Section 53050:Dermatology-related
Except Principal Investigator
Dermatology
Keywords
Principal Investigator
メラノーマ / 循環腫瘍細胞 / 制御性T細胞 / 腫瘍特異的免疫応 / 癌遺伝子 / 分子標的薬 / CTLA抗体薬 / PD1抗体薬 / BRAF遺伝子 / 遺伝子変異 … More / 免疫チェックポイント阻害薬 / 分子標的治療 / 体細胞変異 / 分子標的治療薬 / 病期 / 悪性黒色腫 / 薬剤耐性 / 治療効果 / 接着分子 / バイオマーカー / Notchリガンド / Notchシグナリング / MAPK経路 / DELTA-like 3 / Notchシグナル / マクロファージ / 腫瘍浸潤マクロファージ / 制御性Tリンパ球 / 癌 / 免疫療法 / 腫瘍免疫学 / 皮膚腫瘍学 … More
Except Principal Investigator
アトピー性皮膚炎 / AhR / 診断 / バイオマーカー / 免疫逃避 / miRNA / 悪性黒色腫 Less
  • Research Projects

    (8 results)
  • Research Products

    (45 results)
  • Co-Researchers

    (8 People)
  •  Development of the precision medicine for melanoma using circulating tumor celPrincipal Investigator

    • Principal Investigator
      Kiniwa Yukiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Shinshu University
  •  Clarification of mechanism how environmental factors induce atopic dermatitis and exploring new treatments

    • Principal Investigator
      Ogawa Eisaku
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Shinshu University
  •  Investigation of personalized medicine for melanoma and mechanism of drug resistance using circulating tumor cells.Principal Investigator

    • Principal Investigator
      Kiniwa Yukiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Shinshu University
  •  Analysis of role of aryl hydrocarbon receptor for pathophysiology of atopic dermatitis

    • Principal Investigator
      OGAWA Eisaku
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Shinshu University
  •  Notch signaing promotes proliferation and migration of melanoma.Principal Investigator

    • Principal Investigator
      KINIWA Yukiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Shinshu University
  •  Investigation of roles of miRNA in the immunosuppression and clinical use for patients with melanoma

    • Principal Investigator
      KAWAKAMI Yutaka
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Association of chemokines and tumor associated macrophages in induction of regulatory T cells in melanomaPrincipal Investigator

    • Principal Investigator
      KINIWA Yukiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Shinshu University
  •  Analysis of T cell-mediated tumor rejection and regulatory T cell-mediated tumor escape in melanoma.Principal Investigator

    • Principal Investigator
      KINIWA Yukiko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Shinshu University

All 2019 2018 2017 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] 希少疾患用医薬品の採算性ある事業化と適応拡大戦略2018

    • Author(s)
      木庭幸子
    • Total Pages
      8
    • Publisher
      技術情報協会
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Book] 次世代を担う、核酸医薬、免疫療法、遺伝子治療、細胞医薬品の課題と各疾患治療への横断的展開2017

    • Author(s)
      木庭幸子
    • Total Pages
      150
    • Publisher
      技術情報協会
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Book] 1冊でわかる皮膚がん2011

    • Author(s)
      木庭幸子
    • Total Pages
      6
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Book] EBMがん化学療法・分子標的治療法2010

    • Author(s)
      木庭幸子
    • Total Pages
      8
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Book] EBMがん化学療法・分子標的治療法 2010-20112010

    • Author(s)
      木庭幸子
    • Total Pages
      5
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Journal Article] 免疫チェックポイント阻害薬を中止後に、ダカルバジンを使用したメラノーマの3例2019

    • Author(s)
      中村謙太, 芦田敦子, 木庭 幸子, 奥山 隆平
    • Journal Title

      Skin Cancer

      Volume: 33 Pages: 196-200

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Journal Article] Diversity of circulating tumor cells in peripheral blood: Detection of heterogeneous BRAF mutations in a patient with advanced melanoma by single-cell analysis2018

    • Author(s)
      Kiniwa Y, Nakamura K, Mikoshiba A, Akiyama Y, Morimoto A, Okuyama R
    • Journal Title

      J Dermatol Sci

      Volume: 90 Issue: 2 Pages: 211-216

    • DOI

      10.1016/j.jdermsci.2018.01.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04240, KAKENHI-PROJECT-16K10149
  • [Journal Article] Presence of antibodies to striated muscle and acetylcholine receptor in association with occurrence of myasthenia gravis with myositis and myocarditis in a patient with melanoma treated with an anti-PD-1 antibody.2018

    • Author(s)
      Shirai T, Kiniwa Y, Sato R, Sano T, Nakamura K, Mikoshiba Y, Ohashi N, Sekijima Y, okuyama R.
    • Journal Title

      Eur J Cancer

      Volume: 106 Pages: 193-195

    • DOI

      10.1016/j.ejca.2018.10.025

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Journal Article] Type 1 Diabetes in a Melanoma Patient Treated with Ipilimumab after Nivolumab. .2018

    • Author(s)
      Omodaka T, Kiniwa Y, Sato Y, Suwa M, Sato M, Yamaguchi T, Sato A, Miyake T, Okuyama R.
    • Journal Title

      J Dermatol

      Volume: 45

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Journal Article] 5-hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi2014

    • Author(s)
      Uchiyama R, Uhar H, Uchiyama A, Ogawa E, Takazawa Y, Ashida A, Koga H, Hayashi K, Kiniwa Y, Okuyama R
    • Journal Title

      J Dermatol Sci

      Volume: 73 Issue: 2 Pages: 161-163

    • DOI

      10.1016/j.jdermsci.2013.09.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591615, KAKENHI-PROJECT-25461688, KAKENHI-PROJECT-25461689, KAKENHI-PROJECT-26461686
  • [Journal Article] Toll-like receptor 4 signaling promotes the migration of human melanoma cells.2014

    • Author(s)
      Takazawa Y, Kiniwa Y, Ogawa E, Uchiyama A, Ashida A, Uhara H, Goto Y, Okuyama R
    • Journal Title

      Tohoku J Exp Med

      Volume: 234 Pages: 57-65

    • NAID

      130004685014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461688
  • [Journal Article] MAPキナーゼ:NRAS、BRAF、MEK2013

    • Author(s)
      芦田敦子、木庭幸子、宇原久、奥山隆平
    • Journal Title

      Int J Clin Oncol

      Volume: 71 増4 Pages: 126-129

    • Data Source
      KAKENHI-PROJECT-25461689
  • [Journal Article] 悪性黒色腫の浸潤・転移(2)浸潤・転移に関連する非免疫機序2013

    • Author(s)
      木庭幸子
    • Journal Title

      日本臨床

      Volume: 71 増4 Pages: 171-175

    • Data Source
      KAKENHI-PROJECT-25461689
  • [Journal Article] 悪性黒色腫の循環腫瘍細胞2013

    • Author(s)
      上條史尚、木庭幸子、宇原久、奥山隆平
    • Journal Title

      日本臨床

      Volume: 71 増4 Pages: 93-97

    • Data Source
      KAKENHI-PROJECT-25461689
  • [Journal Article] Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level2012

    • Author(s)
      Sakaizawa K, Goto Y, Kiniwa Y, et al
    • Journal Title

      Br J Cancer

      Volume: 106 Issue: 5 Pages: 939-946

    • DOI

      10.1038/bjc.2012.12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591429, KAKENHI-PROJECT-22791065, KAKENHI-PROJECT-23591614, KAKENHI-PROJECT-23591615, KAKENHI-PROJECT-23591619
  • [Journal Article] ダカルバジン単剤投与が奏効した進行期悪性黒色腫の1例2011

    • Author(s)
      内山龍平、井出葉子、木庭幸子、他
    • Journal Title

      Skin Cancer

      Volume: 25 Pages: 353-357

    • NAID

      10030441957

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Journal Article] メラノサイト特異的蛋白陰性の原発不明悪性黒色腫の1例2011

    • Author(s)
      木庭幸子、大橋敦子、高沢裕子、他
    • Journal Title

      Skin Cancer

      Volume: 26 Pages: 139-142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Journal Article] メラノサイト特異的タンパク陰性の原発不明悪性黒色腫の1例2011

    • Author(s)
      木庭幸子
    • Journal Title

      Skin Cancer

      Volume: 25 Pages: 353-357

    • NAID

      10030441671

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Journal Article] メラノーマの免疫療法最近の動向2010

    • Author(s)
      木庭幸子
    • Journal Title

      癌と化学療法

      Volume: 37 Pages: 629-633

    • Data Source
      KAKENHI-PROJECT-21591429
  • [Journal Article] メラノーマの免疫療法 最近の動向2010

    • Author(s)
      木庭幸子
    • Journal Title

      癌と化学療法

      Volume: 37 Pages: 629-633

    • Data Source
      KAKENHI-PROJECT-21591429
  • [Journal Article] メラノーマにおける免疫回避機構2009

    • Author(s)
      木庭幸子
    • Journal Title

      Skin Cancer 24(2)

      Pages: 159-163

    • Data Source
      KAKENHI-PROJECT-21591429
  • [Journal Article] メラノーマにおける免疫回避機構2009

    • Author(s)
      木庭幸子
    • Journal Title

      癌と化学療法, Skin Cancer

      Volume: 24 Pages: 159-163

    • Data Source
      KAKENHI-PROJECT-21591429
  • [Journal Article] 知っておきたいがん免疫療法・実臨床のトピックス「メラノーマ」の免疫治2008

    • Author(s)
      木庭幸子, 斎田俊明
    • Journal Title

      侵襲と免疫 17(4)

      Pages: 43-44

    • Data Source
      KAKENHI-PROJECT-19591298
  • [Journal Article] 知っておきたいがん免疫療法・実臨床のトピックス「メラノーマ」の免疫治療2008

    • Author(s)
      木庭幸子、斎田俊明
    • Journal Title

      侵襲と免疫 vol.17(4)

      Pages: 43-44

    • Data Source
      KAKENHI-PROJECT-19591298
  • [Journal Article] CD8+ Foxp3+ regulatory T cells mediate immune suppression in prostate cancer2007

    • Author(s)
      Kiniwa Y, Wang HY, Peng W, Peng G, Wheeler T, Thompson T, Wang RF
    • Journal Title

      Clin Cancer Res Dec ; 13(23)

      Pages: 6947-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591298
  • [Patent] 2.抗癌剤投与効果予測方法2017

    • Inventor(s)
      奥山隆平,木庭幸子,秋山泰之,森本敦史,
    • Industrial Property Rights Holder
      奥山隆平,木庭幸子,秋山泰之,森本敦史,
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Presentation] ニボルマブ→イピリムマブ導入症例での重篤irAE2018

    • Author(s)
      木庭幸子
    • Organizer
      第2回甲信メラノーマカンファレンス
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Presentation] BRAF変異メラノーマに対する、BRAF阻害薬、TLR7アゴニスト、PD-1阻害薬の併用療法の解析2018

    • Author(s)
      中村謙太、谷口智憲, 村田眞志, 太田陽介, 木庭幸子, 河上裕, 奧山隆平
    • Organizer
      第9回最新皮膚疾患研究会
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Presentation] BRAF/MEK阻害薬投与中に筋肉内膿瘍をきたした1例2018

    • Author(s)
      木庭幸子
    • Organizer
      メラノーマ分子標的療法セミナー
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Presentation] 悪性黒色腫の病態と遺伝子異常;治療への新しい扉2018

    • Author(s)
      木庭幸子
    • Organizer
      第117回日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Presentation] Diversity of circulating tumor cells in peripheral blood: Detection of heterogeneous BRAF mutations in a patient with advanced melanoma by single-cell analysis.2017

    • Author(s)
      Kiniwa Y, Nakamura K, Mikoshiba A, Uchiyama A, Akiyama Y, Morimoto A, Okuyama R.
    • Organizer
      World Congress of Melanoma
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10149
  • [Presentation] DELTA-LIKE 3 promotes proliferation and migration in melanoma via MAPK activation.2015

    • Author(s)
      Yukiko Kiniwa, Aya Uchiyama, Naomi Kumagai, Eisaku Ogawa, Ryuhei Okuyama
    • Organizer
      Society for Melanoma Research
    • Place of Presentation
      Marriott Marquis(アメリカ,カリフォルニア州,サンフランシスコ)
    • Year and Date
      2015-11-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461689
  • [Presentation] DELTA-LIKE 3 promotes proliferation and migration in melanoma via MAPK activation.2015

    • Author(s)
      木庭幸子、内山彩、熊谷尚美、小川英作、奥山隆平
    • Organizer
      日本研究皮膚科学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Year and Date
      2015-12-11
    • Data Source
      KAKENHI-PROJECT-25461689
  • [Presentation] 日本人におけるメラノーマの遺伝子異常2014

    • Author(s)
      木庭幸子、宇原久
    • Organizer
      日本皮膚科学会総会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2014-05-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461689
  • [Presentation] CD133陽性メラノーマの解析2011

    • Author(s)
      木庭幸子、高沢裕子、内山彩、奥山隆平
    • Organizer
      表皮細胞研究会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-10-29
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Presentation] メラノーマにおけるside populationの解析2010

    • Author(s)
      木庭幸子、高沢裕子、奥山隆平
    • Organizer
      第1回先端医療研究会
    • Place of Presentation
      名古屋市
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Presentation] WT-1specific anti-tumor immune response in melanoma2010

    • Author(s)
      木庭幸子、内山彩、奥山隆平
    • Organizer
      Society for Melanoma Research
    • Place of Presentation
      シドニー
    • Year and Date
      2010-11-07
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Presentation] メラノサイト特異的タンパク陰性の原発不明悪性黒色腫の1例2010

    • Author(s)
      木庭幸子
    • Organizer
      第26回日本皮膚悪性腫瘍学会
    • Place of Presentation
      東京
    • Year and Date
      2010-06-05
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Presentation] WT1-specific anti-tumor immune response in melanoma2010

    • Author(s)
      木庭幸子
    • Organizer
      Society for Melanoma Research
    • Place of Presentation
      シドニー
    • Year and Date
      2010-11-06
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Presentation] メラノーマにおけるside populationの解析2010

    • Author(s)
      木庭幸子
    • Organizer
      第1回 先端医療研究会
    • Place of Presentation
      名古屋市
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Presentation] メラノーマにおける免疫回避機構2009

    • Author(s)
      木庭幸子
    • Organizer
      第25回日本皮膚悪性腫瘍学会シンポジウム
    • Place of Presentation
      岡山市
    • Year and Date
      2009-05-21
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Presentation] メラノーマに対する免疫応答と免疫療法2009

    • Author(s)
      木庭幸子
    • Organizer
      Kumamoto Dermatological Acadeymy
    • Place of Presentation
      熊本市
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-19591298
  • [Presentation] メラノーマにおける免疫回避機構2009

    • Author(s)
      木庭幸子
    • Organizer
      第25回に本皮膚悪性腫瘍学会 シンポジウム
    • Place of Presentation
      岡山市
    • Year and Date
      2009-05-21
    • Data Source
      KAKENHI-PROJECT-21591429
  • [Presentation] Analysis of Regulatory T cells in Melanoma2008

    • Author(s)
      木庭幸子、内山彩、斎田俊明
    • Organizer
      5^<th> International Investigative Dermatology
    • Place of Presentation
      京都市
    • Year and Date
      2008-05-14
    • Data Source
      KAKENHI-PROJECT-19591298
  • [Presentation] Delta-like protein 3 promotes proliferation and migration of melanoma cells.

    • Author(s)
      Yukiko Kiniwa, Ryuhei Okuyama
    • Organizer
      European Society of Dermatological Research
    • Place of Presentation
      コペンハーゲン(デンマーク)
    • Year and Date
      2014-09-10 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25461689
  • 1.  OKUYAMA Ryuhei (80292332)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 12 results
  • 2.  SAIDA Toshiaki (10010381)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  KIDO Kenji (00447765)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  OGAWA Eisaku (20451586)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  KAWAKAMI Yutaka (50161287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  OHTA Shigeki (20365406)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YAGUCHI Tomonori (40424163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  AMAGAI Masayuki (90212563)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

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