Kiniwa Yukiko 木庭幸子

… Alternative Names

KINIWA Yukiko 木庭幸子

Less

Researcher Number	20436893
Other IDs
Affiliation (Current)	2025: 信州大学, 学術研究院医学系, 准教授
Affiliation (based on the past Project Information) *help	2023: 信州大学, 学術研究院医学系, 准教授 2018 – 2020: 信州大学, 学術研究院医学系, 准教授 2014 – 2017: 信州大学, 学術研究院医学系(医学部附属病院), 講師 2014 – 2015: 信州大学, 学術研究院医学系(医学部付属病院), 講師 2011 – 2013: 信州大学, 医学部附属病院, 講師 2011: 信州大学, 医学部・附属病院, 講師 2007 – 2010: Shinshu University, 医学部, 助教
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related Except Principal Investigator Dermatology
Keywords	Principal Investigator メラノーマ / 循環腫瘍細胞 / 制御性T細胞 / 腫瘍特異的免疫応 / 癌遺伝子 / 分子標的薬 / CTLA抗体薬 / PD1抗体薬 / BRAF遺伝子 / 遺伝子変異 … More / 免疫チェックポイント阻害薬 / 分子標的治療 / 体細胞変異 / 分子標的治療薬 / 病期 / 悪性黒色腫 / 薬剤耐性 / 治療効果 / 接着分子 / バイオマーカー / Notchリガンド / Notchシグナリング / MAPK経路 / DELTA-like 3 / Notchシグナル / マクロファージ / 腫瘍浸潤マクロファージ / 制御性Tリンパ球 / 癌 / 免疫療法 / 腫瘍免疫学 / 皮膚腫瘍学 … More Except Principal Investigator アトピー性皮膚炎 / AhR / 診断 / バイオマーカー / 免疫逃避 / miRNA / 悪性黒色腫 Less

Development of the precision medicine for melanoma using circulating tumor celPrincipal Investigator
- Principal Investigator
  
  Kiniwa Yukiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Shinshu University
Clarification of mechanism how environmental factors induce atopic dermatitis and exploring new treatments
- Principal Investigator
  
  Ogawa Eisaku
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Shinshu University
Investigation of personalized medicine for melanoma and mechanism of drug resistance using circulating tumor cells.Principal Investigator
- Principal Investigator
  
  Kiniwa Yukiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Shinshu University
Analysis of role of aryl hydrocarbon receptor for pathophysiology of atopic dermatitis
- Principal Investigator
  
  OGAWA Eisaku
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Shinshu University
Notch signaing promotes proliferation and migration of melanoma.Principal Investigator
- Principal Investigator
  
  KINIWA Yukiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Shinshu University
Investigation of roles of miRNA in the immunosuppression and clinical use for patients with melanoma
- Principal Investigator
  
  KAWAKAMI Yutaka
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Association of chemokines and tumor associated macrophages in induction of regulatory T cells in melanomaPrincipal Investigator
- Principal Investigator
  
  KINIWA Yukiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Shinshu University
Analysis of T cell-mediated tumor rejection and regulatory T cell-mediated tumor escape in melanoma.Principal Investigator
- Principal Investigator
  
  KINIWA Yukiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Shinshu University

All 2019 2018 2017 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

[Book] 希少疾患用医薬品の採算性ある事業化と適応拡大戦略2018
- Author(s)
  木庭幸子
- Total Pages
  8
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-16K10149
[Book] 次世代を担う、核酸医薬、免疫療法、遺伝子治療、細胞医薬品の課題と各疾患治療への横断的展開2017
- Author(s)
  木庭幸子
- Total Pages
  150
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-16K10149
[Book] 1冊でわかる皮膚がん2011
- Author(s)
  木庭幸子
- Total Pages
  6
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-21591429
[Book] EBMがん化学療法・分子標的治療法2010
- Author(s)
  木庭幸子
- Total Pages
  8
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21591429
[Book] EBMがん化学療法・分子標的治療法 2010-20112010
- Author(s)
  木庭幸子
- Total Pages
  5
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21591429
[Journal Article] 免疫チェックポイント阻害薬を中止後に、ダカルバジンを使用したメラノーマの3例2019
- Author(s)
  中村謙太, 芦田敦子, 木庭幸子, 奥山隆平
- Journal Title
  
  Skin Cancer
  
  Volume: 33 Pages: 196-200
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10149
[Journal Article] Diversity of circulating tumor cells in peripheral blood: Detection of heterogeneous BRAF mutations in a patient with advanced melanoma by single-cell analysis2018
- Author(s)
  Kiniwa Y, Nakamura K, Mikoshiba A, Akiyama Y, Morimoto A, Okuyama R
- Journal Title
  
  J Dermatol Sci
  
  Volume: 90 Issue: 2 Pages: 211-216
- DOI
  10.1016/j.jdermsci.2018.01.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04240, KAKENHI-PROJECT-16K10149
[Journal Article] Presence of antibodies to striated muscle and acetylcholine receptor in association with occurrence of myasthenia gravis with myositis and myocarditis in a patient with melanoma treated with an anti-PD-1 antibody.2018
- Author(s)
  Shirai T, Kiniwa Y, Sato R, Sano T, Nakamura K, Mikoshiba Y, Ohashi N, Sekijima Y, okuyama R.
- Journal Title
  
  Eur J Cancer
  
  Volume: 106 Pages: 193-195
- DOI
  10.1016/j.ejca.2018.10.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10149
[Journal Article] Type 1 Diabetes in a Melanoma Patient Treated with Ipilimumab after Nivolumab. .2018
- Author(s)
  Omodaka T, Kiniwa Y, Sato Y, Suwa M, Sato M, Yamaguchi T, Sato A, Miyake T, Okuyama R.
- Journal Title
  
  J Dermatol
  
  Volume: 45
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10149
[Journal Article] 5-hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi2014
- Author(s)
  Uchiyama R, Uhar H, Uchiyama A, Ogawa E, Takazawa Y, Ashida A, Koga H, Hayashi K, Kiniwa Y, Okuyama R
- Journal Title
  
  J Dermatol Sci
  
  Volume: 73 Issue: 2 Pages: 161-163
- DOI
  10.1016/j.jdermsci.2013.09.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591615, KAKENHI-PROJECT-25461688, KAKENHI-PROJECT-25461689, KAKENHI-PROJECT-26461686
[Journal Article] Toll-like receptor 4 signaling promotes the migration of human melanoma cells.2014
- Author(s)
  Takazawa Y, Kiniwa Y, Ogawa E, Uchiyama A, Ashida A, Uhara H, Goto Y, Okuyama R
- Journal Title
  
  Tohoku J Exp Med
  
  Volume: 234 Pages: 57-65
- NAID
  130004685014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461688
[Journal Article] MAPキナーゼ：NRAS、BRAF、MEK2013
- Author(s)
  芦田敦子、木庭幸子、宇原久、奥山隆平
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 71　増4 Pages: 126-129
- Data Source
  KAKENHI-PROJECT-25461689
[Journal Article] 悪性黒色腫の浸潤・転移（２）浸潤・転移に関連する非免疫機序2013
- Author(s)
  木庭幸子
- Journal Title
  
  日本臨床
  
  Volume: 71　増4 Pages: 171-175
- Data Source
  KAKENHI-PROJECT-25461689
[Journal Article] 悪性黒色腫の循環腫瘍細胞2013
- Author(s)
  上條史尚、木庭幸子、宇原久、奥山隆平
- Journal Title
  
  日本臨床
  
  Volume: 71　増4 Pages: 93-97
- Data Source
  KAKENHI-PROJECT-25461689
[Journal Article] Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level2012
- Author(s)
  Sakaizawa K, Goto Y, Kiniwa Y, et al
- Journal Title
  
  Br J Cancer
  
  Volume: 106 Issue: 5 Pages: 939-946
- DOI
  10.1038/bjc.2012.12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591429, KAKENHI-PROJECT-22791065, KAKENHI-PROJECT-23591614, KAKENHI-PROJECT-23591615, KAKENHI-PROJECT-23591619
[Journal Article] ダカルバジン単剤投与が奏効した進行期悪性黒色腫の1例2011
- Author(s)
  内山龍平、井出葉子、木庭幸子、他
- Journal Title
  
  Skin Cancer
  
  Volume: 25 Pages: 353-357
- NAID
  10030441957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591429
[Journal Article] メラノサイト特異的蛋白陰性の原発不明悪性黒色腫の1例2011
- Author(s)
  木庭幸子、大橋敦子、高沢裕子、他
- Journal Title
  
  Skin Cancer
  
  Volume: 26 Pages: 139-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591429
[Journal Article] メラノサイト特異的タンパク陰性の原発不明悪性黒色腫の1例2011
- Author(s)
  木庭幸子
- Journal Title
  
  Skin Cancer
  
  Volume: 25 Pages: 353-357
- NAID
  10030441671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591429
[Journal Article] メラノーマの免疫療法最近の動向2010
- Author(s)
  木庭幸子
- Journal Title
  
  癌と化学療法
  
  Volume: 37 Pages: 629-633
- Data Source
  KAKENHI-PROJECT-21591429
[Journal Article] メラノーマの免疫療法最近の動向2010
- Author(s)
  木庭幸子
- Journal Title
  
  癌と化学療法
  
  Volume: 37 Pages: 629-633
- Data Source
  KAKENHI-PROJECT-21591429
[Journal Article] メラノーマにおける免疫回避機構2009
- Author(s)
  木庭幸子
- Journal Title
  
  Skin Cancer 24(2)
  
  Pages: 159-163
- Data Source
  KAKENHI-PROJECT-21591429
[Journal Article] メラノーマにおける免疫回避機構2009
- Author(s)
  木庭幸子
- Journal Title
  
  癌と化学療法, Skin Cancer
  
  Volume: 24 Pages: 159-163
- Data Source
  KAKENHI-PROJECT-21591429
[Journal Article] 知っておきたいがん免疫療法・実臨床のトピックス「メラノーマ」の免疫治2008
- Author(s)
  木庭幸子, 斎田俊明
- Journal Title
  
  侵襲と免疫 17(4)
  
  Pages: 43-44
- Data Source
  KAKENHI-PROJECT-19591298
[Journal Article] 知っておきたいがん免疫療法・実臨床のトピックス「メラノーマ」の免疫治療2008
- Author(s)
  木庭幸子、斎田俊明
- Journal Title
  
  侵襲と免疫 vol.17(4)
  
  Pages: 43-44
- Data Source
  KAKENHI-PROJECT-19591298
[Journal Article] CD8+ Foxp3+ regulatory T cells mediate immune suppression in prostate cancer2007
- Author(s)
  Kiniwa Y, Wang HY, Peng W, Peng G, Wheeler T, Thompson T, Wang RF
- Journal Title
  
  Clin Cancer Res Dec ; 13(23)
  
  Pages: 6947-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591298
[Patent] 2.抗癌剤投与効果予測方法2017
- Inventor(s)
  奥山隆平，木庭幸子，秋山泰之，森本敦史，
- Industrial Property Rights Holder
  奥山隆平，木庭幸子，秋山泰之，森本敦史，
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K10149
[Presentation] ニボルマブ→イピリムマブ導入症例での重篤irAE2018
- Author(s)
  木庭幸子
- Organizer
  第２回甲信メラノーマカンファレンス
- Data Source
  KAKENHI-PROJECT-16K10149
[Presentation] BRAF変異メラノーマに対する、BRAF阻害薬、TLR7アゴニスト、PD-1阻害薬の併用療法の解析2018
- Author(s)
  中村謙太、谷口智憲, 村田眞志, 太田陽介, 木庭幸子, 河上裕, 奧山隆平
- Organizer
  第9回最新皮膚疾患研究会
- Data Source
  KAKENHI-PROJECT-16K10149
[Presentation] BRAF/MEK阻害薬投与中に筋肉内膿瘍をきたした１例2018
- Author(s)
  木庭幸子
- Organizer
  メラノーマ分子標的療法セミナー
- Data Source
  KAKENHI-PROJECT-16K10149
[Presentation] 悪性黒色腫の病態と遺伝子異常;治療への新しい扉2018
- Author(s)
  木庭幸子
- Organizer
  第117回日本皮膚科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10149
[Presentation] Diversity of circulating tumor cells in peripheral blood: Detection of heterogeneous BRAF mutations in a patient with advanced melanoma by single-cell analysis.2017
- Author(s)
  Kiniwa Y, Nakamura K, Mikoshiba A, Uchiyama A, Akiyama Y, Morimoto A, Okuyama R.
- Organizer
  World Congress of Melanoma
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10149
[Presentation] DELTA-LIKE 3 promotes proliferation and migration in melanoma via MAPK activation.2015
- Author(s)
  Yukiko Kiniwa, Aya Uchiyama, Naomi Kumagai, Eisaku Ogawa, Ryuhei Okuyama
- Organizer
  Society for Melanoma Research
- Place of Presentation
  Marriott Marquis（アメリカ，カリフォルニア州，サンフランシスコ）
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461689
[Presentation] DELTA-LIKE 3 promotes proliferation and migration in melanoma via MAPK activation.2015
- Author(s)
  木庭幸子、内山彩、熊谷尚美、小川英作、奥山隆平
- Organizer
  日本研究皮膚科学会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-25461689
[Presentation] 日本人におけるメラノーマの遺伝子異常2014
- Author(s)
  木庭幸子、宇原久
- Organizer
  日本皮膚科学会総会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-25461689
[Presentation] CD133陽性メラノーマの解析2011
- Author(s)
  木庭幸子、高沢裕子、内山彩、奥山隆平
- Organizer
  表皮細胞研究会
- Place of Presentation
  横浜市
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-21591429
[Presentation] メラノーマにおけるside populationの解析2010
- Author(s)
  木庭幸子、高沢裕子、奥山隆平
- Organizer
  第1回先端医療研究会
- Place of Presentation
  名古屋市
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21591429
[Presentation] WT-1specific anti-tumor immune response in melanoma2010
- Author(s)
  木庭幸子、内山彩、奥山隆平
- Organizer
  Society for Melanoma Research
- Place of Presentation
  シドニー
- Year and Date
  2010-11-07
- Data Source
  KAKENHI-PROJECT-21591429
[Presentation] メラノサイト特異的タンパク陰性の原発不明悪性黒色腫の1例2010
- Author(s)
  木庭幸子
- Organizer
  第26回日本皮膚悪性腫瘍学会
- Place of Presentation
  東京
- Year and Date
  2010-06-05
- Data Source
  KAKENHI-PROJECT-21591429
[Presentation] WT1-specific anti-tumor immune response in melanoma2010
- Author(s)
  木庭幸子
- Organizer
  Society for Melanoma Research
- Place of Presentation
  シドニー
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-21591429
[Presentation] メラノーマにおけるside populationの解析2010
- Author(s)
  木庭幸子
- Organizer
  第1回先端医療研究会
- Place of Presentation
  名古屋市
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21591429
[Presentation] メラノーマにおける免疫回避機構2009
- Author(s)
  木庭幸子
- Organizer
  第25回日本皮膚悪性腫瘍学会シンポジウム
- Place of Presentation
  岡山市
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-21591429
[Presentation] メラノーマに対する免疫応答と免疫療法2009
- Author(s)
  木庭幸子
- Organizer
  Kumamoto Dermatological Acadeymy
- Place of Presentation
  熊本市
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19591298
[Presentation] メラノーマにおける免疫回避機構2009
- Author(s)
  木庭幸子
- Organizer
  第25回に本皮膚悪性腫瘍学会シンポジウム
- Place of Presentation
  岡山市
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-21591429
[Presentation] Analysis of Regulatory T cells in Melanoma2008
- Author(s)
  木庭幸子、内山彩、斎田俊明
- Organizer
  5^<th> International Investigative Dermatology
- Place of Presentation
  京都市
- Year and Date
  2008-05-14
- Data Source
  KAKENHI-PROJECT-19591298
[Presentation] Delta-like protein 3 promotes proliferation and migration of melanoma cells.
- Author(s)
  Yukiko Kiniwa, Ryuhei Okuyama
- Organizer
  European Society of Dermatological Research
- Place of Presentation
  コペンハーゲン（デンマーク）
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25461689

1. OKUYAMA Ryuhei (80292332)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
2. SAIDA Toshiaki (10010381)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. KIDO Kenji (00447765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OGAWA Eisaku (20451586)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. KAWAKAMI Yutaka (50161287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OHTA Shigeki (20365406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YAGUCHI Tomonori (40424163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AMAGAI Masayuki (90212563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kiniwa Yukiko 木庭 幸子

KINIWA Yukiko 木庭 幸子

Research Projects

Research Products

Co-Researchers

Development of the precision medicine for melanoma using circulating tumor celPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarification of mechanism how environmental factors induce atopic dermatitis and exploring new treatments

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of personalized medicine for melanoma and mechanism of drug resistance using circulating tumor cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of role of aryl hydrocarbon receptor for pathophysiology of atopic dermatitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Notch signaing promotes proliferation and migration of melanoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of roles of miRNA in the immunosuppression and clinical use for patients with melanoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Association of chemokines and tumor associated macrophages in induction of regulatory T cells in melanomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of T cell-mediated tumor rejection and regulatory T cell-mediated tumor escape in melanoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 希少疾患用医薬品の採算性ある事業化と適応拡大戦略2018

Author(s)

Total Pages

Publisher

Data Source

[Book] 次世代を担う、核酸医薬、免疫療法、遺伝子治療、細胞医薬品の課題と各疾患治療への横断的展開2017

Author(s)

Total Pages

Publisher

Data Source

[Book] 1冊でわかる皮膚がん2011

Author(s)

Total Pages

Publisher

Data Source

[Book] EBMがん化学療法・分子標的治療法2010

Author(s)

Total Pages

Publisher

Data Source

[Book] EBMがん化学療法・分子標的治療法 2010-20112010

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] 免疫チェックポイント阻害薬を中止後に、ダカルバジンを使用したメラノーマの3例2019

Author(s)

Kiniwa Yukiko 木庭幸子

KINIWA Yukiko 木庭幸子

[Journal Article] メラノーマの免疫療法最近の動向2010