WATANABE MIZUKI 渡邉瑞貴

… Alternative Names

WATANABE Mizuki 渡邉瑞貴

渡邉瑞貴ワタナベミズキ

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Researcher Number	20507173
Other IDs	https://orcid.org/0000-0001-7209-5713
Affiliation (Current)	2025: 北海道大学, 薬学研究院, 准教授
Affiliation (based on the past Project Information) *help	2025: 北海道大学, 薬学研究院, 准教授 2020 – 2023: 北海道大学, 薬学研究院, 准教授 2016 – 2020: 北海道大学, 薬学研究院, 講師 2015: 北海道大学, 薬学研究科(研究院), 講師 2013 – 2014: 京都大学, 化学研究所, 助教 … More 2012: 京都大学, 物質ー細胞統合システム拠点, 研究員 2009: 北大, 薬学研究科(研究院), 助教 2008: Hokkaido University, 大学院・薬学研究院, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Drug development chemistry / Chemical biology / Chemical biology Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields
Keywords	Principal Investigator ペプチドミメティクス / 三次元構造制御 / ペプチド / フォルダマー / 三次元構造 / ヘリックス / 配座制御 / 脂質代謝 / タンパク質二次構造 / β-ストランド … More / α-ヘリックス / ストランド / 膜透過性 / 環状ペプチド / SCAP / SREBP / ビタミンD / 脂質代謝制御 / 化合物ライブラリー / 有機合成化学 / 医薬品化学 / ケミカルバイオロジー / 構造活性相関 / 医薬分子設計 / 配座制限誘導体 / NOS / シクロプロパン / 三次元的多様性 … More Except Principal Investigator 高分子間相互作用 / αヘリックス / ホールダマー / 膜透過性ペプチド / 環状ペプチド / ペプチドミメティクス / タンパク質間相互作用 / 三次元多様性 / シクロプロパン Less

主鎖配座制御を基盤としたタンパク質二次構造ミメティクスの創薬研究Principal Investigator
- Principal Investigator
  
  渡邉瑞貴
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Hokkaido University
Development Research on Peptide Foldamers Based on Conformationally Restricted Amino AcidsPrincipal Investigator
- Principal Investigator
  
  渡邉瑞貴
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Hokkaido University
Development of bioactive peptides based on molecular design with conformational restrictionPrincipal Investigator
- Principal Investigator
  
  Watanabe Mizuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Hokkaido University
Medicinal chemistry for developing molecules regulating interactions between biological macromolecules
- Principal Investigator
  
  Shuto Satoshi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Hokkaido University
Development of a new foldamer as a mimetic of alfa-helixPrincipal Investigator
- Principal Investigator
  
  WATANABE Mizuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hokkaido University
Analysis of regulation of lipid metabolism by vitamin D metabolitePrincipal Investigator
- Principal Investigator
  
  WATANABE Mizuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Hokkaido University
  Kyoto University
Development of synthetic small molecules that control the lipid biosynthesisPrincipal Investigator
- Principal Investigator
  
  WATANABE Mizuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Kyoto University
シクロプロパンの構造特性を活用した配座制御型分子設計による医薬分子の創製研究Principal Investigator
- Principal Investigator
  
  渡邉瑞貴
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hokkaido University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book Patent

[Book] ペプチド創薬の最前線2019
- Author(s)
  木曽良明（監修）、吉矢拓、髙山健太郎、生長幸之助、金井求、西村仁孝、新原光貴、加藤敬行、菅裕明、出水庸介、小早川拓也、玉村啓和、金井和昭、秋山泰、大上雅史、吉川寧、和久井直樹、鳴海哲夫、後藤佑樹、長谷川慎、田中誠、渡邉瑞貴
- Total Pages
  265
- Publisher
  シーエムシー出版
- ISBN
  9784781314174
- Data Source
  KAKENHI-PROJECT-19K06965
[Journal Article] Development of Conformationally Restricted Negamycin Derivatives for Potent Readthrough Activity2023
- Author(s)
  Omura Noriko、Taguchi Akihiro、Kuwahara Tomoki、Hamada Keisuke、Watanabe Mizuki、Nakakuki Masanori、Konno Sho、Takayama Kentaro、Taniguchi Atsuhiko、Nomura Toshifumi、Shuto Satoshi、Hayashi Yoshio
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 14 Issue: 12 Pages: 1807-1814
- DOI
  10.1021/acsmedchemlett.3c00424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-22KJ2791
[Journal Article] 合理的な分子設計によるδ-ペプチドフォルダマーの創出2023
- Author(s)
  渡邉瑞貴
- Journal Title
  
  月間　細胞
  
  Volume: 55 Pages: 69-72
- Data Source
  KAKENHI-PROJECT-22K06494
[Journal Article] S. Helix-forming aliphatic homo-δ-peptide foldamers based on the conformational restriction effects of cyclopropane.2022
- Author(s)
  89.Nagata, M.; Watanabe, M.; Doi, R.; Uemura, M.; Ochiai, N.; Ichinose, W.; Fujiwara, K.; Kameda, T.; Sato, Y.; Takeuchi, K.; Shuto,
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: - Issue: 5 Pages: 970-980
- DOI
  10.1039/d2ob01715f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-20H03378
[Journal Article] Synthesis of γ-Aminobutyric Acid (GABA) Analogues Conformationally Restricted by Bicyclo[3.1.0]hexane/hexene or [4.1.0]Heptane/heptene Backbones as Potent Betaine/GABA Transporter Inhibitors2022
- Author(s)
  Keisuke Mitsui, Maria E. K. Lie, Naoki Saito, Koichi Fujiwara, Mizuki Watanabe, Petrine Wellendorph, Satoshi Shuto
- Journal Title
  
  Organic Letters
  
  Volume: 24 Issue: 23 Pages: 4151-5154
- DOI
  10.1021/acs.orglett.2c01346
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-19K06965
[Journal Article] Design and Synthesis of Cyclopropane Congeners of Resolvin E3, an Endogenous Pro-Resolving Lipid Mediator, as Its Stable Equivalents.2022
- Author(s)
  (2)Arai S, Fujiwara K, Kojima M, Aoki-Saito H, Yatomi M, Saito T, Koga Y, Fukuda H, Watanabe M, Matsunaga S, Hisada T, Shuto S
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 87(15) Issue: 15 Pages: 10501-10508
- DOI
  10.1021/acs.joc.2c01110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08404, KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-22K08227, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-20K06941, KAKENHI-PROJECT-21K15215
[Journal Article] Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside2022
- Author(s)
  H. Higashida, K. Furuhara, O. Lopatina, M. Gerasimenko, O. Hori, T. Hattori, Y. Hayashi, S. M. Cherepanov, A. A. Shabalova, A. B. Salmina, K. Minami, T. Yuhi, C. Tsuji, P. Y. Fu, Z. Liu, S. Luo, A. Zhang, S. Yokoyama, S. Shuto, M. Watanabe, K. Fujiwara, S. Munesue, A. Harashima, Y. Yamamoto
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 858070-858070
- DOI
  10.3389/fnins.2022.858070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-22K18540, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-21H02695, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-20K07323
[Journal Article] Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine‐Loaded Lipid Nanoparticles2022
- Author(s)
  Masaki Gomi, Yu Sakurai, Minami Sato, Hiroki Tanaka, Yumi Miyatake, Koichi Fujiwara, Mizuki Watanabe, Satoshi Shuto, Yuta Nakai, Kota Tange, Hiroto Hatakeyama, Hidetaka Akita
- Journal Title
  
  Advanced Healthcare Materials
  
  Volume: 12 Issue: 9 Pages: 2202528-2202528
- DOI
  10.1002/adhm.202202528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-22KJ0465
[Journal Article] Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT12021
- Author(s)
  280.S. Kickinger, M. E. K. Lie, A. Suemasa, A. Al-Khawaja, K. Fujiwara, M. Watanabe, K. S. Wilhelmsen, C. B. Falk-Petersen, B. Frolund, S. Shuto, G. F. Ecker, P. Wellendorth
- Journal Title
  
  Front. Chem
  
  Volume: 16
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01014
[Journal Article] Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT12021
- Author(s)
  Petrine Wellendorph, Stefanie Kickinger, Maria EK Lie, Akihiro Suemasa, Anas Al-Khawaja, Koichi Fujiwara, Mizuki Watanabe, Kristine S Wilhelmsen, Christina B Falk-Petersen, Bente Frolund, Satoshi Shuto, Gerhard Franz Ecker
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 9 Pages: 736457-736457
- DOI
  10.3389/fchem.2021.736457
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06965
[Journal Article] Structure, solubility, and permeability relationships in a diverse middle molecule library2021
- Author(s)
  Kayoko Kanamitsu et al.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 37 Pages: 127847-127847
- DOI
  10.1016/j.bmcl.2021.127847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PROJECT-19H03345, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-21K05059
[Journal Article] Synthesis of Resolvin E1 and Its Conformationally Restricted Cyclopropane Congeners with Potent Anti-Inflammatory Effect2021
- Author(s)
  274.K. Ishimura, H. Fukuda, K. Fujiwara, R. Muromoto, K. Hirashima, Y. Murakami, M. Watanabe, J. Ishihara, T. Matsuda, S. Shuto
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 12 Pages: 1464-1469
- NAID
  120007186305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01014
[Journal Article] Synthesis of Resolvin E1 and Its Conformationally Restricted Cyclopropane Congeners with Potent Anti-Inflammatory Effect2021
- Author(s)
  Ishimura Kohei、Fukuda Hayato、Fujiwara Koichi、Muromoto Ryuta、Hirashima Koki、Murakami Yuto、Watanabe Mizuki、Ishihara Jun、Matsuda Tadashi、Shuto Satoshi
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 12 Issue: 2 Pages: 256-261
- DOI
  10.1021/acsmedchemlett.0c00639
- NAID
  120007186305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-20K06941
[Journal Article] Conformational Restriction of Histamine with a Rigid Bicyclo[3.1.0]hexane Scaffold Provided Selective H3 Receptor Ligands2020
- Author(s)
  Watanabe Mizuki、Kobayashi Takaaki、Ito Yoshihiko、Yamada Shizuo、Shuto Satoshi
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 16 Pages: 3562-3562
- DOI
  10.3390/molecules25163562
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-19H01014
[Journal Article] A Macrocyclic Peptide Library with a Structurally Constrained Cyclopropane‐containing Building Block Leads to Thiol‐independent Inhibitors of Phosphoglycerate Mutase2020
- Author(s)
  Okuma Rika、Kuwahara Tomoki、Yoshikane Takafumi、Watanabe Mizuki、Dranchak Patricia、Inglese James、Shuto Satoshi、Goto Yuki、Suga Hiroaki
- Journal Title
  
  Chemistry - An Asian Journal
  
  Volume: 15 Issue: 17 Pages: 2631-2636
- DOI
  10.1002/asia.202000700
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-19K22243, KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-20H02866
[Journal Article] Synthesis of Resolvin E3, a Proresolving Lipid Mediator, and Its Deoxy Derivatives: Identification of 18-Deoxy-resolvin E3 as a Potent Anti-Inflammatory Agent2020
- Author(s)
  Fukuda Hayato、Ikeda Hiroyuki、Muromoto Ryuta、Hirashima Koki、Ishimura Kohei、Fujiwara Koichi、Aoki-Saito Haruka、Hisada Takeshi、Watanabe Mizuki、Ishihara Jun、Matsuda Tadashi、Shuto Satoshi
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 85 Issue: 21 Pages: 14190-14200
- DOI
  10.1021/acs.joc.0c01701
- NAID
  120007168587
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08382, KAKENHI-PROJECT-18K08404, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-20K06941, KAKENHI-PROJECT-19H03364
[Journal Article] Design and Synthesis of Benzene Congeners of Resolvin E2, a Proresolving Lipid Mediator, as Its Stable Equivalents2020
- Author(s)
  Murakami Yuto、Fukuda Hayato、Muromoto Ryuta、Hirashima Koki、Ishimura Kohei、Fujiwara Koichi、Ishihara Jun、Matsuda Tadashi、Watanabe Mizuki、Shuto Satoshi
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 11 Issue: 4 Pages: 479-484
- DOI
  10.1021/acsmedchemlett.9b00596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08360, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-20K06941, KAKENHI-PROJECT-19H01014
[Journal Article] Synthesis of oxytocin derivatives lipidated via a carbonate or carbamate linkage as a long-acting therapeutic agent for social impairment-like behaviors2019
- Author(s)
  Cherepanov Stanislav M.、Miura Risako、Shabalova Anna A.、Ichinose Wataru、Yokoyama Shigeru、Fukuda Hayato、Watanabe Mizuki、Higashida Haruhiro、Shuto Satoshi
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 15 Pages: 3358-3363
- DOI
  10.1016/j.bmc.2019.06.018
- NAID
  120007126060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-17K08360
[Journal Article] Synthesis of Enantiomerically Pure 1,2,3-Trisubstituted Cyclopropane Nucleosides Using Pd-Catalyzed Substitution via Directing Group-Mediated C(sp3)?H Activation as a Key Step2019
- Author(s)
  Minami Takaaki、Fukuda Kohtaro、Hoshiya Naoyuki、Fukuda Hayato、Watanabe Mizuki、Shuto Satoshi
- Journal Title
  
  Organic Letters
  
  Volume: 21 Issue: 3 Pages: 656-659
- DOI
  10.1021/acs.orglett.8b03785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08360, KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-17K15476, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-16H05106
[Journal Article] Nutrient-Based Chemical Library as a Source of Energy Metabolism Modulators2019
- Author(s)
  Furuta Tomoyuki、Mizukami Yuya、Asano Lisa、Kotake Kenjiro、Ziegler Slava、Yoshida Hiroki、Watanabe Mizuki、Sato Shin-ichi、Waldmann Herbert、Nishikawa Makiya、Uesugi Motonari
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 14 Issue: 9 Pages: 1860-1865
- DOI
  10.1021/acschembio.9b00444
- NAID
  120006769193
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06965, KAKENHI-PLANNED-17H06408, KAKENHI-PROJECT-19H00922
[Journal Article] Development of a Highly Potent Analogue and a Long-Acting Analogue of Oxytocin for the Treatment of Social Impairment-Like Behaviors2019
- Author(s)
  Ichinose W, Cherepanov SM, Shabalova AA, Yokoyama S, Yuhi T, Yamaguchi H, Watanabe A, Yamamoto Y, Okamoto H, Horike S, Terakawa J, Daikoku T, Watanabe M, Mano N, Higashida H, Shuto S
- Journal Title
  
  J Med Chem
  
  Volume: - Issue: 7 Pages: 3297-3310
- DOI
  10.1021/acs.jmedchem.8b01691
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06889, KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-18K06742, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-19H00388
[Journal Article] Synthesis of Chiral cis-Cyclopropane Bearing Indole and Chromone as Potential TNFα Inhibitors2018
- Author(s)
  Kanada Ryutaro、Tanabe Makoto、Muromoto Ryuta、Sato Yukina、Kuwahara Tomoki、Fukuda Hayato、Arisawa Mitsuhiro、Matsuda Tadashi、Watanabe Mizuki、Shuto Satoshi
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 83 Issue: 15 Pages: 7672-7682
- DOI
  10.1021/acs.joc.8b00466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08360, KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-17K15476, KAKENHI-PROJECT-16H05106, KAKENHI-PROJECT-15KT0063, KAKENHI-PUBLICLY-18H04260, KAKENHI-PROJECT-26288051
[Journal Article] Resolvin E1, but not resolvins E2 and E3, promotes fMLF-induced ROS generation in human neutrophils2018
- Author(s)
  Unno Yuka、Sato Yoshinori、Fukuda Hayato、Ishimura Kohei、Ikeda Hiroyuki、Watanabe Mizuki、Tansho-Nagakawa Shigeru、Ubagai Tsuneyuki、Shuto Satoshi、Ono Yasuo
- Journal Title
  
  FEBS Letters
  
  Volume: 592 Issue: 16 Pages: 2706
- DOI
  10.1002/1873-3468.13215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00883, KAKENHI-PROJECT-17K08360, KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-17K15476
[Journal Article] Design and synthesis of cyclopropane-based conformationally restricted GABA analogues as selective inhibitors for betaine/GABA transporter 12018
- Author(s)
  Suemasa Akihiro、Watanabe Mizuki、Kobayashi Takaaki、Suzuki Hiroe、Fukuda Hayato、Minami Masabumi、Shuto Satoshi
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 28 Issue: 20 Pages: 3395-3399
- DOI
  10.1016/j.bmcl.2018.08.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08360, KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-17K15476
[Journal Article] Live-cell imaging of multiple endogenous mRNAs permits the direct observation of RNA granule dynamics2018
- Author(s)
  Yatsuzuka Kenji、Sato Shin-ichi、Pe Kathleen Beverly、Katsuda Yousuke、Takashima Ippei、Watanabe Mizuki、Uesugi Motonari
- Journal Title
  
  Chemical Communications
  
  Volume: 54 Issue: 52 Pages: 7151-7154
- DOI
  10.1039/c8cc03805h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19200, KAKENHI-PROJECT-17K15476, KAKENHI-PLANNED-17H06408, KAKENHI-PROJECT-26220206
[Journal Article] Design and synthesis of histamine H3/H4 receptor ligands with a cyclopropane scaffold2018
- Author(s)
  Watanabe Mizuki、Kobayashi Takaaki、Ito Yoshihiko、Fukuda Hayato、Yamada Shizuo、Arisawa Mitsuhiro、Shuto Satoshi
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 28 Issue: 23-24 Pages: 3630-3633
- DOI
  10.1016/j.bmcl.2018.10.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08360, KAKENHI-PROJECT-17K15476, KAKENHI-PROJECT-15KT0063, KAKENHI-PUBLICLY-18H04260, KAKENHI-PROJECT-26288051
[Journal Article] Synthesis of 8-Substituted Analogues of Cyclic ADP-4-Thioribose and Their Unexpected Identification as Ca2+-Mobilizing Full Agonists2017
- Author(s)
  Takano Satoshi、Tsuzuki Takayoshi、Murayama Takashi、Kameda Tomoshi、Kumaki Yasuhiro、Sakurai Takashi、Fukuda Hayato、Watanabe Mizuki、Arisawa Mitsuhiro、Shuto Satoshi
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 60 Issue: 13 Pages: 5868-5875
- DOI
  10.1021/acs.jmedchem.7b00540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KT0063, KAKENHI-PROJECT-17K15476, KAKENHI-PUBLICLY-16H01026
[Journal Article] Cyclopropane-Based Peptidomimetics Mimicking Wide-Ranging Secondary Structures of Peptides: Conformational Analysis and Their Use in Rational Ligand Optimization.2017
- Author(s)
  A. Mizuno, T. Kameda, T. Kuwahara, H. Endoh, Y. Ito, S. Yamada, K. Hasegawa, A. Yamano, M. Watanabe, M. Arisawa, S. Shuto
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 23 Issue: 13 Pages: 3159-3168
- DOI
  10.1002/chem.201605312
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-15KT0063, KAKENHI-PROJECT-17K15476, KAKENHI-PROJECT-16H05106, KAKENHI-PUBLICLY-16H01026
[Journal Article] Vitamin D metabolite, 25-Hydroxyvitamin D, regulates lipid metabolism by inducing degradation of SREBP/SCAP.2017
- Author(s)
  Asano, L., Watanabe, M., Ryoden, Y., Usuda, K., Yamaguchi, T., Khambu, B., Takashima, M., Sato, S., Sakai, J., Nagasawa, K., Uesugi, M.
- Journal Title
  
  Cell Chem Biol.
  
  Volume: 24 Issue: 2 Pages: 207-217
- DOI
  10.1016/j.chembiol.2016.12.017
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26220206, KAKENHI-PROJECT-14J12469, KAKENHI-PROJECT-26350972, KAKENHI-PROJECT-26440005, KAKENHI-PROJECT-16H06390
[Journal Article] Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability2015
- Author(s)
  Kang, S.; Watanabe, M.; Jacobs, J.C.; Yamaguchi, M.; Dahesh, S.; Nizet, V.; Leyh, T. S.; Silverman, R.B.
- Journal Title
  
  Eur. J. Med. Chem.
  
  Volume: 90 Pages: 448-461
- DOI
  10.1016/j.ejmech.2014.11.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26350972, KAKENHI-PROJECT-26861546
[Journal Article] Live-cell Imaging of Endogenous mRNAs with a Small Molecule2015
- Author(s)
  Sato, S.*, Watanabe, M., Katsuda, Y., Murata, A., Wang, D. O., Uesugi M.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 54 Issue: 6 Pages: 1855-1858
- DOI
  10.1002/anie.201410339
- NAID
  120005619801
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26102728, KAKENHI-PROJECT-26220206, KAKENHI-PROJECT-26350972, KAKENHI-PROJECT-26440005, KAKENHI-PROJECT-26560445, KAKENHI-PROJECT-26702038
[Journal Article] Synthetic molecules that protect cells from anoikis and their use in cell transplantation2014
- Author(s)
  Frisco-C., H.L.; Watanabe, M.; Okumura, N.; Kusamori, K.; Takemoto, N.; Takaya, J.; Sato, S.; Yamazoe, S.; Takakura, Y.; Kinoshita, S.; Nishikawa, M.; Koizumi, N.; Uesugi, M.
- Journal Title
  
  Angew. Chem., Int. Ed.
  
  Volume: 53 Issue: 42 Pages: 11208-11213
- DOI
  10.1002/ange.201405829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26350972, KAKENHI-PROJECT-26560445
[Journal Article] Small-molecule inhibitors of SREBP activation - potential for new treatment of metabolic disorders2013
- Author(s)
  Mizuki Watanabe, Motonari Uesugi
- Journal Title
  
  Med Chem Commun
  
  Volume: 4 Issue: 11 Pages: 1422-1433
- DOI
  10.1039/c3md00177f
- NAID
  120005526695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710260
[Journal Article] Three-Dimensional Structural Diversity-Oriented Peptidomimetics Based on the Cyclopropylic Strain2013
- Author(s)
  Akira Mizuno
- Journal Title
  
  Org. Lett.
  
  Volume: 15 Issue: 7 Pages: 1686-1689
- DOI
  10.1021/ol400469w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23246013, KAKENHI-PROJECT-24390023, KAKENHI-PROJECT-24710260, KAKENHI-PUBLICLY-25105702, KAKENHI-PUBLICLY-23105502
[Journal Article] 不活性な第一級C-H結合１つを選択的にC-OH結合へ変える2013
- Author(s)
  渡邉瑞貴
- Journal Title
  
  ファルマシア
  
  Volume: 49 Pages: 154-154
- NAID
  110009995690
- Data Source
  KAKENHI-PROJECT-24710260
[Journal Article] Preparation of nonracemic bromomethylenecyclopropane and its use in Suzuki-Miyaura coupling; synthesis of the arylmethyl-cis-cyclopropane structure core.2013
- Author(s)
  Makoto TANABE
- Journal Title
  
  J. Org. Chem.
  
  Volume: 78 Issue: 23 Pages: 11714-11720
- DOI
  10.1021/jo401675z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23246013, KAKENHI-PROJECT-24390023, KAKENHI-PROJECT-24710260, KAKENHI-PUBLICLY-25105702
[Journal Article] トピックス"不活性な第一級C–H結合1つを選択的にC–OH結合へ変える"2013
- Author(s)
  渡邉瑞貴
- Journal Title
  
  ファルマシア
  
  Volume: vol.49 Pages: 154-154
- Data Source
  KAKENHI-PROJECT-24710260
[Journal Article] 被曝による急性死が薬で防げる！？2012
- Author(s)
  渡邉瑞貴
- Journal Title
  
  化学
  
  Volume: 67 Pages: 60-61
- Data Source
  KAKENHI-PROJECT-24710260
[Journal Article] 注目の論文"被曝による急性死が薬で防げる!?"2012
- Author(s)
  渡邉瑞貴
- Journal Title
  
  化学
  
  Volume: vol.67 Pages: 60-61
- Data Source
  KAKENHI-PROJECT-24710260
[Patent] Compositions and methods for the treatment of metabolic disorders2016
- Inventor(s)
  上杉志成、渡邉瑞貴、他
- Industrial Property Rights Holder
  上杉志成、渡邉瑞貴、他
- Industrial Property Rights Type
  特許
- Filing Date
  2016-05-24
- Acquisition Date
  2016-09-08
- Overseas
- Data Source
  KAKENHI-PROJECT-26350972
[Patent] Vitamin D3 derivatives and pharmaceutical use thereof2014
- Inventor(s)
  渡邉瑞貴、浅野理沙、長澤和夫、上杉志成
- Industrial Property Rights Holder
  渡邉瑞貴、浅野理沙、長澤和夫、上杉志成
- Industrial Property Rights Type
  特許
- Filing Date
  2014-12-24
- Overseas
- Data Source
  KAKENHI-PROJECT-26350972
[Patent] Compositions and methods for the treatment of metabolic disorders2014
- Inventor(s)
  上杉志成、渡邉瑞貴、他
- Industrial Property Rights Holder
  上杉志成、渡邉瑞貴、他
- Industrial Property Rights Type
  特許
- Filing Date
  2014-06-20
- Overseas
- Data Source
  KAKENHI-PROJECT-26350972
[Patent] Preparation of fatostatin A and derivatives and compositions thereof for the treatment of obesity2014
- Inventor(s)
  上杉志成、渡邉瑞貴、他
- Industrial Property Rights Holder
  上杉志成、渡邉瑞貴、他
- Industrial Property Rights Type
  特許
- Filing Date
  2014-05-05
- Overseas
- Data Source
  KAKENHI-PROJECT-26350972
[Patent] Prodrugs of fluorinated mevalonates to inhibit the mevalonate pathway of streptococcus pneumoniae2013
- Inventor(s)
  Richard B. Silverman, Mizuki Watanabe, Soosong Kang
- Industrial Property Rights Holder
  Northwestern University
- Industrial Property Rights Type
  特許
- Acquisition Date
  2013-09-19
- Overseas
- Data Source
  KAKENHI-PROJECT-24710260
[Patent] Prodrugs of fluorinated mevalonates to inhibit the mevalonate pathway of streptococcus pneumoniae2013
- Inventor(s)
  渡邉瑞貴　他
- Industrial Property Rights Holder
  Northwestern University
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-28
- Acquisition Date
  2013-09-19
- Overseas
- Data Source
  KAKENHI-PROJECT-24710260
[Presentation] 生物活性を有する中分子天然物と環状ペプチドの合成と膜透過性2023
- Author(s)
  市川聡、勝山彬、山本一貴、薬師寺文華、渡邉瑞貴
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 中分子創薬の課題克服を指向した構造-物性相関解析：光学活性シクロプロパン含有環状ペプチド類の構造と溶解性、受動拡散性、細胞膜透過性、P-gp基質性相関2023
- Author(s)
  宮地弘幸、金光佳世子、石井真由美、渡邊恵里、佐藤優希菜、長田貴行、山﨑祐季、柏木仁、菅原満、周東智、重田育照、渡邉瑞貴、前仲勝実
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 合理的分子設計に基づくペプチドフォルダマーの創出とペプチドミメティクスとしての応用2023
- Author(s)
  渡邉瑞貴、永田真、落合七彩、横峰真琳、森本淳平、山東信介、竹内恒、周東智
- Organizer
  第17回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 配座制御を基盤とした膜透過性環状ペプチドの創製と構造解析2023
- Author(s)
  山﨑祐季、久米田博之、松井耕平、藤原広一、渡邉瑞貴、周東智
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] シクロプロパン骨格を有するSTAT3阻害剤の創出研究2023
- Author(s)
  渡邉瑞貴、林真由、太田克美、浅井章良、周東智
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] シクロプロパン骨格を有するSTAT3阻害剤の創出研究2023
- Author(s)
  渡邉瑞貴、林真由、太田克美、浅井章良、周東智
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] N-スルホニルイミンを用いたＺ選択的Juliaオレフィン化反応の開発2023
- Author(s)
  地崎巧真，藤原広一，周東智，渡邉瑞貴
- Organizer
  第49回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 中分子創薬の課題克服を指向した構造-物性相関解析：光学活性シクロプロパン含有環状ペプチド類の構造と溶解性、受動拡散性、細胞膜透過性、P-gp基質性相関2023
- Author(s)
  宮地弘幸、金光佳世子、石井真由美、渡邊恵里、佐藤優希菜、長田貴行、山﨑祐季、柏木仁、菅原満、周東智、重田育照、渡邉瑞貴、前仲勝実
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 生物活性を有する中分子天然物と環状ペプチドの合成と膜透過性2023
- Author(s)
  市川聡、勝山彬、山本一貴、薬師寺文華、渡邉瑞貴
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] シクロプロパン骨格を有するSTAT3阻害剤の創出研究2023
- Author(s)
  渡邉瑞貴
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] Development and Application of Conformationally Restricted Cyclic Peptides with High Passive Permeability2023
- Author(s)
  高島悠太、荒木優里奈、山﨑祐季、中瀬生彦、周東智、渡邉瑞貴
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] DEVELOPMENT OF β-STRAND-LIKE FOLDAMERS CONSISTING OF CYCLOPROPANE γ-AMINO ACIDS THAT FUNCTION AS PEPTIDOMIMETICS2023
- Author(s)
  Akiko Yoshida, Shunsuke Kita, Ryotaro Sakashita, Katsumi Maenaka, Satoshi Shuto, and Mizuki Watanabe
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] シクロプロパンによる配座制御を基盤とした生物活性ペプチドフォルダマーの設計と合成2023
- Author(s)
  渡邉瑞貴，永田真，落合七彩，吉田朗子，周東智
- Organizer
  第49回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] α,δ-二置換シクロプロパンδ-アミノ酸を基盤としたヘリカルフォルダマーの創製とタンパク質間相互作用阻害分子への応用2023
- Author(s)
  渡邉瑞貴、落合七彩、永田真、横峰真琳、森本淳平、山東信介、竹内恒、周東智
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 高い受動拡散性をもつ配座制限環状ペプチドの開発とその応用研究2023
- Author(s)
  高島悠太、山﨑祐季、松井耕平、渡邉瑞貴、周東智
- Organizer
  日本薬学会北海道支部例会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 配座制御を基盤とした膜透過性環状ペプチドの創製と構造解析2023
- Author(s)
  山﨑祐季、久米田博之、松井耕平、藤原広一、渡邉瑞貴、周東智
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 高い受動拡散性をもつ配座制限環状ペプチドの開発とその応用研究2023
- Author(s)
  高島悠太、荒木優里奈、山﨑祐季、松井耕平、渡邉瑞貴、中瀬生彦、周東智
- Organizer
  日本ケミカルバイオロジー学会　第17回年会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] スピロ[2,5]オクタンを基本骨格としたペプチドミメティクスによる Bcl-2 ファミリータンパク質阻害剤の創製研究2022
- Author(s)
  渡邉瑞貴、坂下遼太郎、桑原智希、吉田朗子、林真由、水野彰、藤原広一、竹内恒、周東智
- Organizer
  日本ケミカルバイオロジー学会　第16回年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 抗炎症脂質レゾルビンE2の1,4,7-トリエン-ベンゼン置換による安定等価体の創製研究2022
- Author(s)
  田中伸英，村上侑斗，平島洸基、福田隼、藤原広一、渡邉瑞貴、室本竜太、松田正、周東智
- Organizer
  第48回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] シクロプロパンによる配座制御を基軸としたペプチドフォルダマーの開発2022
- Author(s)
  渡邉瑞貴
- Organizer
  日本薬学会　第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] シクロプロパンによる配座制御に基づいた膜透過性環状ペプチドの開発2022
- Author(s)
  高島悠太、山崎祐季、佐藤優希菜、植村麻衣、松井耕平、藤原広一、渡邉瑞貴、周東智
- Organizer
  日本薬学会　第142年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 抗炎症脂質レゾルビンE2の1,4,7-トリエン-ベンゼン置換による安定等価体の創製研究2022
- Author(s)
  田中伸英，村上侑斗，平島洸基、福田隼、藤原広一、渡邉瑞貴、室本竜太、松田正、周東智
- Organizer
  第48回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 配座制御を基盤とした膜透過性環状ペプチドの研究2022
- Author(s)
  山﨑祐季、久米田博之、藤原広一、渡邉瑞貴、周東智
- Organizer
  第54回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 1,2,3-三置換シクロプロパンを骨格とするSTAT3阻害剤の創製研究2022
- Author(s)
  林真由，甘利穂乃花，太田克美，藤原広一，渡邉瑞貴，浅井章良，周東智
- Organizer
  第48回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 3-エピデオキシネガマイシンの分子空間固定が及ぼすリードスルー活性への影響2022
- Author(s)
  大村紀子、田口晃弘、濱田圭佑、桑原智希、渡邉瑞貴、中久木正則、今野翔、高山健太郎、谷口敦彦、乃村俊史、周東智、林良雄
- Organizer
  日本ケミカルバイオロジー学会　第16回年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Study To Identify Cyclic Peptides With Membrane Permeability And Bioactivity By Cyclopropane-Based Conformational Restriction Strategy2022
- Author(s)
  山﨑祐季、久米田博之、松井耕平、藤原広一、渡邉瑞貴、周東智
- Organizer
  第59回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] スピロ[2,5]オクタンを基本骨格としたペプチドミメティクスによる Bcl-2 ファミリータンパク質阻害剤の創製研究2022
- Author(s)
  渡邉瑞貴、坂下遼太郎、桑原智希、吉田朗子、林真由、水野彰、藤原広一、竹内恒、周東智
- Organizer
  日本ケミカルバイオロジー学会　第16回年会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] イミンを用いたZ選択的Juliaオレフィン化反応の開発2022
- Author(s)
  地崎巧真、藤原広一、渡邉瑞貴、周東智_
- Organizer
  第34回万有札幌シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] DEVELOPMENT OF HELIX-FORMING α/δ-PEPTIDE FOLDAMERS BY CYCLOPROPANE-BASED CONFORMATIONAL RESTRICTION STRATEGY TARGETING PROTEIN_PROTEIN INTERACTIONS2022
- Author(s)
  落合七彩、永田真、竹内恒、藤原広一、渡邉瑞貴、周東智
- Organizer
  第59回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Michael-Wittig反応によるスキップジエン構築を鍵反応とするレゾルビンE4およびdeoxy体の合成研究2022
- Author(s)
  櫻田海都，藤原広一，渡邉瑞貴, 周東智
- Organizer
  第48回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 分子空間固定型ネガマイシンの合成とそのリードスルー活性評価2022
- Author(s)
  大村紀子、田口晃弘、濵田圭佑、桑原智希、渡邉瑞貴、中久木正則、今野翔、高山健太郎、谷口敦彦、乃村俊史、周東智、林良雄
- Organizer
  日本薬学会　第142年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 配座制御を基盤とした膜透過性環状ペプチドの研究2022
- Author(s)
  山﨑祐季、久米田博之、藤原広一、渡邉瑞貴、周東智
- Organizer
  第54回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] がんワクチン療法への応用を見据えたホスファチジルセリン誘導体の創製研究2022
- Author(s)
  宮武結実, 佐藤南, 佐藤耀, 藤原広一, 渡邉瑞貴, 周東智
- Organizer
  生体機能関連化学部会　若手の会第33回サマースクール
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 配座制御による膜透過性環状ペプチドの開発とその応用研究2022
- Author(s)
  高島悠太、松井耕平、藤原広一、渡邉瑞貴、周東智
- Organizer
  生体機能関連化学部会　若手の会第33回サマースクール
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 1,2,3-三置換シクロプロパンを骨格とするSTAT3阻害剤の創製研究2022
- Author(s)
  林真由，甘利穂乃花，太田克美，藤原広一，渡邉瑞貴，浅井章良，周東智
- Organizer
  第48回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Study To Identify Cyclic Peptides With Membrane Permeability And Bioactivity By Cyclopropane-Based Conformational Restriction Strategy2022
- Author(s)
  山﨑祐季、久米田博之、松井耕平、藤原広一、渡邉瑞貴、周東智
- Organizer
  第59回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] DEVELOPMENT OF HELIX-FORMING α/δ-PEPTIDE FOLDAMERS BY CYCLOPROPANE-BASED CONFORMATIONAL RESTRICTION STRATEGY TARGETING PROTEIN_PROTEIN INTERACTIONS2022
- Author(s)
  落合七彩、永田真、竹内恒、藤原広一、渡邉瑞貴、周東智
- Organizer
  第59回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] がんワクチン療法への応用を見据えたホスファチジルセリン誘導体の創製研究2022
- Author(s)
  宮武結実, 佐藤南, 佐藤耀, 藤原広一, 渡邉瑞貴, 周東智
- Organizer
  生体機能関連化学部会　若手の会第33回サマースクール
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Michael-Wittig反応によるスキップジエン構築を鍵反応とするレゾルビンE4およびdeoxy体の合成研究2022
- Author(s)
  櫻田海都，藤原広一，渡邉瑞貴, 周東智
- Organizer
  第48回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] 配座制御による膜透過性環状ペプチドの開発とその応用研究2022
- Author(s)
  高島悠太、松井耕平、藤原広一、渡邉瑞貴、周東智
- Organizer
  生体機能関連化学部会　若手の会第33回サマースクール
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] イミンを用いたZ選択的Juliaオレフィン化反応の開発2022
- Author(s)
  地崎巧真、藤原広一、渡邉瑞貴、周東智_
- Organizer
  第34回万有札幌シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 3-エピデオキシネガマイシンの分子空間固定が及ぼすリードスルー活性への影響2022
- Author(s)
  大村紀子、田口晃弘、濵田圭佑、桑原智希、渡邉瑞貴、中久木正則、今野翔、高山健太郎、谷口敦彦、乃村俊史、周東智、林良雄
- Organizer
  日本ケミカルバイオロジー学会　第16回年会
- Data Source
  KAKENHI-PROJECT-22K06494
[Presentation] スピロ[2,5]オクタンを基本骨格としたペプチドミメティクスによる Bcl-2 ファミリータンパク質阻害剤の創製研究2022
- Author(s)
  渡邉瑞貴
- Organizer
  日本ケミカルバイオロジー学会　第16回年会
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] スピロシクロプロパン型ペプチド模倣体に基づくBcl-2ファミリータンパク質阻害剤の創製研究2021
- Author(s)
  坂下遼太郎、桑原智希、藤原広一、渡邉瑞貴、周東智
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] シクロプロパンδ-アミノ酸を基盤としたヘリカルフォルダマーの創製研究2021
- Author(s)
  落合七彩、永田真、藤原広一、渡邉瑞貴、周東智
- Organizer
  第53回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 炎症収束脂質レゾルビンE3の安定等価体の創製研究2021
- Author(s)
  新井将太、藤原広一、福田隼、渡邉瑞貴、青木遥、矢冨正清、古賀康彦、齋藤従道、久田剛志、周東智
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Synthesis of Conformationally Restricted GABA Analogues as Betaine/GABA Transporter BGT1 Inhibitors: Construction of the Bicyclo[3.1.0] hexene and [4.1.0]heptene backbones by RCMs with a Common Diene Substrate2021
- Author(s)
  Naoki Saito, Keisuke Mitsui, Koichi Fujiwara, Mizuki Watanabe, Satoshi Shuto
- Organizer
  13th AFMC International Medicinal Chemistry Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 逆マルコフニコフ型アルキンヒドロアミノ化による3-デアザアデニン環の構築と応用2021
- Author(s)
  今田圭祐，山田真輝，藤原広一，渡邉瑞貴，周東智
- Organizer
  第47回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Development of Cyclic Peptides with Membrane Permeability by Cyclopropane-Based Conformational Restriction Strategy2021
- Author(s)
  Yuki Yamazaki, Mai Uemura, Yukina Sato, Kouhei Matsui, Nanami Kato, Yoh Takekuma, Mitsuru Sugawara, Mizuki Watanabe, Satoshi Shuto
- Organizer
  13th AFMC International Medicinal Chemistry Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Design and Synthesis of Benzene Congeners of specialized proesolving lipid mediator resolving E2 as its Stable Equivalents2021
- Author(s)
  Shinei Tanaka, Koichi Fujiwara, Yuto Murakami, Hayato Fukuda, Jun Ishihara, Mizuki Watanabe, Satoshi Shuto
- Organizer
  13th AFMC International Medicinal Chemistry Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 抗炎症収束性脂質レゾルビン類をプロトタイプとする創薬化学研究2021
- Author(s)
  藤原広、村上侑斗、池田紘之、福田隼、石原淳、渡邉瑞貴、周東智
- Organizer
  反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] 強力な抗炎症活性を有するレゾルビンE1の安定誘導体の創出研究2021
- Author(s)
  小坂篤生、藤原広一、渡邉瑞貴、周東智
- Organizer
  第47回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Design and synthesis of novel helical foldamers based on cyclopropane δ-amino acids2020
- Author(s)
  WATANABE, Mizuki; NAGATA, Makoto; TAKEUCHI, Kou; DOI, Ryohei; FUJIWARA, Koichi; SATO, Yoshihiro; SHUTO, Satoshi
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] サイクリック ADP-リボースの安定拮抗剤としての 6”-フルオロ-8-置換誘導体の合成2020
- Author(s)
  佐竹俊哉,　横井健斗, 藤原広一, 渡邉瑞貴, 周東智
- Organizer
  第49回　複素環化学討論会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] シクロプロパン骨格を有する大環状ペプチドライブラリーの構築及び応用2020
- Author(s)
  大熊　里佳・桑原　智希・渡邉　瑞貴・周東　智・後藤　佑樹・菅　裕明
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] シクロプロパン鎖導入環状ペプチド化合物の膜透過性および吸収性の評価2020
- Author(s)
  加藤七海、植村真衣、松井耕平、渡邉瑞貴、武隈洋、周東智、菅原満
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] シクロプロパンδ-アミノ酸を基盤としたヘリカルフォルダマーの開発2020
- Author(s)
  渡邉瑞貴
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 炎症収束性脂質レゾルビン類をプロトタイプとする創薬化学研究2020
- Author(s)
  藤原広一，村上侑斗，池田紘之，福田隼，石原淳，渡邉瑞貴，周東智
- Organizer
  反応と合成の進歩 2020特別企画シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Improvement of Membrane Permeability of Cyclic Peptides By Conformational Restriction Using Cyclopropane2019
- Author(s)
  Mizuki Watanabe, Yukina Sato, Mai Uemura, Nanami Kato, Kouhei Matsui, Yoh Takekuma, Mitsuru Sugawara, Koh Takeuchi, Satoshi Shuto
- Organizer
  23rd Korean Peptide Protein Society Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] スピロシクロプロパン型αヘリックス・βストランドミメティクスに基づくp53/MDM2結合阻害剤の創製2019
- Author(s)
  桑原智希、水野彰、竹内恒、広川貴次、浅井章良、渡邉瑞貴、周東智
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] 環状ペプチド低分子化方法論の確立を目指した三次元多様型シクロプパンペチドミメティスの開発研究三次元多様型シクロプパンペチドミメティスの開発研究2019
- Author(s)
  杉山洸, 一ノ瀬亘, 広川貴次, 渡邉瑞貴, 周東智
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] シクロプロパンδ-アミノ酸を基盤とした新規フォルダマーの開発2019
- Author(s)
  永田真, 土井良平, 竹内恒、亀田倫史、藤原広一, 渡邉瑞貴, 周東智
- Organizer
  第52回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] Design and synthesis of selective BGT-1 inhibitors based on the conformational restriction strategy2019
- Author(s)
  三井桂佑,末政亮大,小林嵩明,Petrine Wellendorph,人羅菜津子,南雅文,藤原広一,渡邉瑞貴,周東智
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] 炎症収束脂質レゾルビン E2のスキップジエン構造をベンゼン環で置換した安定等価体創製研究2019
- Author(s)
  村上侑斗, 福田隼, 石村航平, 平島洸基, 室本竜太, 渡邉瑞貴, 松田正, 周東智
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] 配座制御による環状ペプチドの膜透過性の向上2019
- Author(s)
  渡邉瑞貴
- Organizer
  第14回トランスポーター研究会
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] スピロシクロプロパン構造を基盤としたαヘリックスミメティクスの創製研究2019
- Author(s)
  坂下遼太郎, 桑原智希, 藤原広一, 渡邉瑞貴, 周東智
- Organizer
  第52回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] Improvement of Membrane Permeability of Cyclic Peptides By Conformational Restriction Using Cyclopropane2019
- Author(s)
  Mizuki Watanabe, Yukina Sato, Mai Uemura, Nanami Kato, Kouhei Matsui, Yoh Takekuma, Mitsuru Sugawara, Satoshi Shuto
- Organizer
  12th AFMC International Medicinal Chemistry Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Synthesis of Enantiomerically Pure 1,2,3-Trisubstituted Cyclopropane Nucleosides2019
- Author(s)
  酒井仁，福多洸太朗，星谷尚亨，福田隼，渡邉瑞貴，周東智
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] DEVELOPMENT OF MEMBRANE PERMEABLE CYCLIC PEPTIDES AS STAT3 DIMERIZATION INHIBITORS: A CONFORMATIONAL RESTRICTION STRATEGY FOR REGURATING PROTEIN-PROTEIN INTERACTIONS2019
- Author(s)
  Takayuki Osada, Kouhei Matsui, Koichi Fujiwara, Katsumi Ota, Akira Asai, Mizuki Watanabe, and Satoshi Shuto
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] 配座制御による環状ペプチドの膜透過性の向上2019
- Author(s)
  渡邉瑞貴
- Organizer
  第14回トランスポーター研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] 配座制御を基盤とした分子設計による創薬化学研究2019
- Author(s)
  渡邉瑞貴
- Organizer
  日本薬学会北海道支部第146回例会
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] 配座制御を基盤とした細胞膜透過性・STAT3二量化阻害環状ペプチドの創製研究2019
- Author(s)
  Takayuki Osada, Kouhei Matsui, Katsumi Ota, Koichi Fujiwara, Akira Asai, Mizuki Watanabe, and Satoshi Shuto
- Organizer
  第52回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] DESIGN AND SYNTHESIS OF NOVEL HELICAL FOLDAMERS BASED ON CYCLOPROPANE Δ-AMINO ACIDS2019
- Author(s)
  永田真, 竹内恒、土井良平、亀田倫史、藤原広一, 佐藤美洋, 渡邉瑞貴, 周東智
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] シクロプロパンδ-アミノ酸を基盤とした新規フォルダマーの開発2019
- Author(s)
  永田真, 土井良平, 竹内恒、亀田倫史、藤原広一, 渡邉瑞貴, 周東智
- Organizer
  第52回若手ペプチド夏の勉強会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Improvement of Membrane Permeability of Cyclic Peptides By Conformational Restriction Using Cyclopropane2019
- Author(s)
  Mizuki Watanabe,Yukina Sato,Mai Uemura,Nanami Kato,Kouhei Matsui,Yoh Takekuma,Mitsuru Sugawara,Koh Takeuchi,Satoshi Shuto
- Organizer
  23rd Korean Peptide Protein Society Symposium
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] DESIGN AND SYNTHESIS OF NOVEL HELICAL FOLDAMERS2019
- Author(s)
  永田真, 竹内恒、土井良平、亀田倫史、藤原広一, 佐藤美洋, 渡邉瑞貴, 周東智
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Improvement of Membrane Permeability of Cyclic Peptides By Conformational Restriction Using Cyclopropane2019
- Author(s)
  Mizuki Watanabe, Yukina Sato, Mai Uemura, Nanami Kato, Kouhei Matsui, Yoh Takekuma, Mitsuru Sugawara, Satoshi Shuto
- Organizer
  12th AFMC International Medicinal Chemistry Symposium
- Data Source
  KAKENHI-PROJECT-19H01014
[Presentation] 配座制御を基盤とした分子設計による創薬化学研究2019
- Author(s)
  渡邉瑞貴
- Organizer
  日本薬学会北海道支部第146回例会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] DEVELOPMENT OF MEMBRANE PERMEABLE CYCLIC PEPTIDES AS STAT3 DIMERIZATION INHIBITORS: A CONFORMATIONAL RESTRICTION STRATEGY FOR REGURATING PROTEIN-PROTEIN INTERACTIONS2019
- Author(s)
  Takayuki Osada, Kouhei Matsui, Koichi Fujiwara, Katsumi Ota, Akira Asai, Mizuki Watanabe, and Satoshi Shuto
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K06965
[Presentation] Conformationally Restricted Cyclic Peptides Based on the Structural Properties of Cyclopropane2018
- Author(s)
  Mizuki Watanabe, Mai Uemura, Yukina Sato, Nanami Kato, Yoh Takekuma, Mitsuru Sugawara, Koh Takeuchi, Satoshi Shuto
- Organizer
  8th Peptide Enginierring Meeting (PEM8-2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] ペプチドの"形"を制御して"機能"を変える2018
- Author(s)
  渡邉瑞貴
- Organizer
  第50回若手ペプチド夏の勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] アデノホスチンAをリードとしたIP3検出プローブの創出2018
- Author(s)
  渡邉瑞貴、森川優輝、大浦泰、福田隼、森田貴雄、谷村明彦、周東智
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] GABAトランスポーターサブタイプ選択的阻害剤の創出を目的とするGABA配座制限誘導体の設計と合成2018
- Author(s)
  末政亮大、中田和彰、小林嵩明、福田隼、渡邉瑞貴、井手聡一郎、人羅菜津子、南雅文、周東智
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] Improvement of Membrane Permeability of Cyclic Peptides By Conformational Restriction Using Cyclopropane2018
- Author(s)
  Mizuki Watanabe, Yukina Sato, Mai Uemura, Nanami Kato, Kouhei Matsui, Hayato Fukuda, Yoh Takekuma, Mitsuru Sugawara, Satoshi Shuto
- Organizer
  The 24th Peptide Forum in Kyoto, 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] Pd触媒を用いたC(sp3)-H活性化反応を鍵段階とする光学活性1,2,3-三置換シクロプロパンヌクレオシドの合成2018
- Author(s)
  南貴覚，福多洸太朗，星谷尚亨，福田隼，渡邉瑞貴，周東智
- Organizer
  第44回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] シクロプロパン δ-アミノ酸を基盤とした新規フォルダマーの創製研究2018
- Author(s)
  永田真、桑原智希、一ノ瀬亘、渡邉瑞貴、周東智
- Organizer
  日本薬学会北海道支部第 145回例会
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] シクロプロパンの構造特性に基づく膜透過性環状ペプチドの設計と合成2018
- Author(s)
  植村真衣, 加藤七海,松井耕平, 桑原智希, 渡邉瑞貴, 福田隼, 竹内恒, 広川貴次, 武隈洋, 菅原満, 周東　智
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] サイトトリエニンAの合成研究2018
- Author(s)
  佐藤晋平，福田隼，渡邉瑞貴，周東智
- Organizer
  第30回万有札幌シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] サイトトリエニンAの合成研究2018
- Author(s)
  佐藤晋平，福田隼，渡邉瑞貴，周東智
- Organizer
  第44回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] trans-1, 2-シクロプロパンジアミンおよびジカルボン酸からなるオリゴアミドの合成研究2018
- Author(s)
  山田圭恭, 一ノ瀬亘, 福田隼, 渡邉瑞貴, 周東智
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] Synthetic Study of Cytotrienin A2018
- Author(s)
  Shimpei Sato, Hayato Fukuda, Mizuki Watanabe, Satoshi Shuto
- Organizer
  7th EuCheMS Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] Improvement of Membrane Permeability of Cyclic Peptides By Conformational Restriction Using Cyclopropane2018
- Author(s)
  Mizuki Watanabe, Yukina Sato, Mai Uemura, Nanami Kato, Kouhei Matsui, Hayato Fukuda, Yoh Takekuma, Mitsuru Sugawara, Satoshi Shuto
- Organizer
  10th International Peptide Symposium（第55回ペプチド討論会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] 炎症収束性脂質レゾルビンE1配座制限誘導体の設計と合成2017
- Author(s)
  石村航平，室本竜太，平島洸基，福田隼，渡邉瑞貴，松田正, 周東智
- Organizer
  第15回次世代を担う有機化学シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] 25‐ヒドロキシビタミンDによるSREBP-SCAPの分解メカニズムの解明2017
- Author(s)
  浅野理沙、渡邉瑞貴、領田優太、長澤和夫、上杉志成
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26350972
[Presentation] Spiro-cyclopropane type α-helix/β-strand mimimetics targeting protein-protein interactions2017
- Author(s)
  Tomoki Kuwahara, Akira Mizuno, Hayato Fukuda, Mizuki Watanabe, Satoshi Shuto
- Organizer
  254th ACS National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] 1-アルキル-3-デアザアデニン環の構築を鍵とした3-デアザ-cADPcRの合成2017
- Author(s)
  山田真輝、金田龍太郎、高木耕治、福田隼、渡邉瑞貴、周東智
- Organizer
  第４７回複素環化学討論会
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] シクロプロパンの立体及び立体電子特性に基づくペプチドミメティクス ―αヘリックス／βストランドミメティクス及び膜透過ミメティクスの開発―2017
- Author(s)
  桑原智希，植村真衣，水野彰，一ノ瀬亘，松井耕平，福田隼，渡邉瑞貴，周東智
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] cADPR 安定アンタゴニストの創製を目指した1-アルキル-3-デアザアデニン骨格の合成2017
- Author(s)
  山田真輝、金田龍太郎、高木耕治福田隼、渡邉瑞貴、周東智
- Organizer
  第64回北海道薬学大会（薬学会支部第144回例会）
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] 光学活性1,2,3-三置換シクロプロパンヌクレオシドの合成2017
- Author(s)
  南貴覚、福多洸太朗、星谷尚亨、福田隼、渡邉瑞貴、周東智
- Organizer
  第29回万有札幌シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] 配座制御を基盤とした機能性ペプチドの開発2017
- Author(s)
  渡邉瑞貴
- Organizer
  若手研究者のための有機化学札幌セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] Development of Conformationally Restricted Peptides and Peptidomimetics Based on the Structural Features of Cyclopropane2017
- Author(s)
  Mizuki Watanabe
- Organizer
  The 3rd HU-TMU-KU Joint Symposium for Pharmaceutical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15476
[Presentation] 細胞内Ca2+動員情報伝達系の機構解明を目指した環状ADP-リボース誘導体の設計と合成2016
- Author(s)
  渡邉瑞貴、佐藤隆俊、加藤広太郎、福田隼、村山尚、東田陽博、周東智
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26350972
[Presentation] ケミカルバイオロジーによるビタミンD誘導体の新機能研究2016
- Author(s)
  渡邉瑞貴
- Organizer
  日本薬学会　第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-26350972
[Presentation] 25‐ヒドロキシビタミンDによるSCAP/SREBPの分解メカニズムの解明2016
- Author(s)
  浅野理沙、渡邉瑞貴、領田優太、長澤和夫、上杉志成
- Organizer
  第58回天然有機化合物討論会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-26350972
[Presentation] 内因性小分子による脂質生合成抑制機構の解明2015
- Author(s)
  渡邉瑞貴、浅野理沙、領田優太、薄田晃佑、飯田圭介、佐藤慎一、長澤和夫、上杉志成
- Organizer
  日本ケミカルバイオロジー学会　第10回年会
- Place of Presentation
  東北大学百周年記念会館　川内萩ホール（宮城県仙台市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-26350972
[Presentation] ビタミン D 誘導体のケミカルバイオロジー研究2015
- Author(s)
  渡邉瑞貴
- Organizer
  第1回有機化学を基盤とした創薬研究シンポジウム
- Place of Presentation
  定山渓ホテル（北海道札幌市）
- Year and Date
  2015-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26350972
[Presentation] 転写因子SREBPの活性化を阻害する内因性化合物2013
- Author(s)
  領田優太, 渡邉瑞貴, Bilon KHAMB, 白川貴詩, 佐藤慎一, 川添嘉徳, 酒井寿郎, 上杉志成
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24710260
[Presentation] 転写因子SREBPの活性化を阻害する内因性化合物2013
- Author(s)
  領田優太、渡邉瑞貴、Bilon KHAMB、白川貴詩、佐藤慎一、川添嘉徳、酒井寿郎、上杉志成
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24710260
[Presentation] ぺプチドの多様な立体配座を模倣する配座制御型ペプチドミメティクスの創製2013
- Author(s)
  水野彰. 渡邉瑞貴, 亀田倫史, 山田静雄, 東田陽博, 有澤光弘, 周東智
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24710260
[Presentation] ペプチドの多様な立体配座を模倣する配座制御型ペプチドミメティクスの創製2013
- Author(s)
  水野彰、渡邉瑞貴、亀田倫史、山田静雄、東田陽博、有澤光弘、周東智
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24710260
[Presentation] Development of small molecules that control lipid biosynthesis2012
- Author(s)
  Mizuki Watanabe, Shinji Kamizuki, Yuta Ryoden, Motonari Uesugi
- Organizer
  CLS-iCeMS Joint Symposium
- Place of Presentation
  中国・北京北京大学
- Data Source
  KAKENHI-PROJECT-24710260
[Presentation] Crucial role of the SREBP pathway in the proliferation of human melanoma cells2012
- Author(s)
  五十嵐政智, 山内祥生, 渡邉瑞貴, 上杉志成, 古川鋼一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24710260
[Presentation] Development of small molecules that control lipid biosynthesis2012
- Author(s)
  Mizuki Watanabe, Shinji Kamizuki, Yuta Ryoden, Motonari Uesugi
- Organizer
  CLS-iCeMS Joint Symposium
- Place of Presentation
  中国　北京大学
- Data Source
  KAKENHI-PROJECT-24710260
[Presentation] Crucial role of the SREBP pathway in the proliferation of human melanoma cells2012
- Author(s)
  五十嵐政智、山内祥生、渡邉瑞貴、上杉志成、古川鋼一
- Organizer
  第８５回日本生化学会大会
- Place of Presentation
  福岡　マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24710260
[Presentation] 脂質生合成を抑制する内因性小分子化合物
- Author(s)
  渡邉瑞貴
- Organizer
  第56回天然有機化合物討論会
- Place of Presentation
  高知
- Year and Date
  2014-10-15 – 2014-10-17
- Data Source
  KAKENHI-PROJECT-26350972
[Presentation] A Small-Molecule Based Method for Live-Cell Imaging of an Endogenous RNA
- Author(s)
  佐藤慎一、渡邉瑞貴、上杉志成
- Organizer
  Mesoscopic Chemical Biology -Integrated Chemical-Physical Systems Towards Cell Control
- Place of Presentation
  京都大学iCeMS本館
- Invited
- Data Source
  KAKENHI-PROJECT-24710260

1. Shuto Satoshi (70241346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 小松康雄 (30271670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 藤原広一 (40837853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 後藤佑樹 (70570604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SATO Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. HISADA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 福田隼

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
8. 有澤光弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 上杉志成

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 青木悠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山本靖彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WATANABE MIZUKI 渡邉 瑞貴

WATANABE Mizuki 渡邉 瑞貴

渡邉 瑞貴 ワタナベ ミズキ

Research Projects

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主鎖配座制御を基盤としたタンパク質二次構造ミメティクスの創薬研究Principal Investigator

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Development Research on Peptide Foldamers Based on Conformationally Restricted Amino AcidsPrincipal Investigator

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Development of bioactive peptides based on molecular design with conformational restrictionPrincipal Investigator

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Medicinal chemistry for developing molecules regulating interactions between biological macromolecules

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Development of a new foldamer as a mimetic of alfa-helixPrincipal Investigator

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Analysis of regulation of lipid metabolism by vitamin D metabolitePrincipal Investigator

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Development of synthetic small molecules that control the lipid biosynthesisPrincipal Investigator

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シクロプロパンの構造特性を活用した配座制御型分子設計による医薬分子の創製研究Principal Investigator

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[Book] ペプチド創薬の最前線2019

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[Journal Article] Development of Conformationally Restricted Negamycin Derivatives for Potent Readthrough Activity2023

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[Journal Article] 合理的な分子設計によるδ-ペプチドフォルダマーの創出2023

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[Journal Article] S. Helix-forming aliphatic homo-δ-peptide foldamers based on the conformational restriction effects of cyclopropane.2022

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[Journal Article] Synthesis of γ-Aminobutyric Acid (GABA) Analogues Conformationally Restricted by Bicyclo[3.1.0]hexane/hexene or [4.1.0]Heptane/heptene Backbones as Potent Betaine/GABA Transporter Inhibitors2022

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[Journal Article] Design and Synthesis of Cyclopropane Congeners of Resolvin E3, an Endogenous Pro-Resolving Lipid Mediator, as Its Stable Equivalents.2022

WATANABE MIZUKI 渡邉瑞貴

WATANABE Mizuki 渡邉瑞貴

渡邉瑞貴ワタナベミズキ