Nakagawa Hitoshi 中川仁

Researcher Number	20533730
Other IDs
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2025: 奈良県立医科大学, 医学部, 助教 2020: 奈良県立医科大学, 医学部附属病院, 助教 2015 – 2020: 奈良県立医科大学, 医学部附属病院, 研究員 2016: 奈良県立医科大学, 医学部附属病院, 診療助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine Except Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine
Keywords	Principal Investigator ネプリライシン / ナトリウム利尿ペプチド / BNP / ANP / CNP / ｃGMP / 心不全 / 食塩 / guanylyl cyclase-A / 交感神経 / ミネラルコルチコイド受容体 … More Except Principal Investigator … More 発症メカニズム / HFpEF / RNA sequence / モデルマウス / RNA sequencing / phenotyping / AI / 収縮性の保持された心不全 / pathophysiology / heart failure / SGLT2 / 緩和 / 心不全 / エンドオブライフ / 循環器 / 終末期医療 / アドバンスケア / 循環器疾患 Less

左室駆出率の保たれた心不全の心臓ミネラルコルチコイド受容体へのSGLT2の作用の検討Principal Investigator
- Principal Investigator
  
  中川仁
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Nara Medical University
Investigation of pathophysiology and novel therapeutic target in heart failure with preserved ejection fraction focused on SGLT2.
- Principal Investigator
  
  彦惣俊吾
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Nara Medical University
ネプリライシンの心不全改善効果に寄与する基質の優位性の解明Principal Investigator
- Principal Investigator
  
  中川仁
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Nara Medical University
収縮性の保持された心不全の発症・進展機序の解明に関する研究
- Principal Investigator
  
  斎藤能彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Nara Medical University
Cardiac Neprilysin Plays an Important Role in Hypertensive Cardiac RemodelingPrincipal Investigator
- Principal Investigator
  
  Nakagawa Hitoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Nara Medical University
The inhibitory effect of ANP on sympathetic nervous activity via mineralocorticoid receptorPrincipal Investigator
- Principal Investigator
  
  Nakagawa Hitoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Nara Medical University
Research to build a system to support decisions on end-of-life care of patients with cardiovascular diseases
- Principal Investigator
  
  Okayama Satoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Nara Medical University

All 2022 2021 2019 2016 2015

All Journal Article Presentation

[Journal Article] Roles of Natriuretic Peptides and the Significance of Neprilysin in Cardiovascular Diseases2022
- Author(s)
  Nakagawa Hitoshi、Saito Yoshihiko
- Journal Title
  
  Biology
  
  Volume: 11 Issue: 7 Pages: 1017-1017
- DOI
  10.3390/biology11071017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08192
[Journal Article] Local Action of Neprilysin Exacerbates Pressure Overload Induced Cardiac Remodeling2021
- Author(s)
  Nakagawa Hitoshi、Kumazawa Takuya、Onoue Kenji、Nakada Yasuki、Nakano Tomoya、Ishihara Satomi、Minamino Naoto、Hosoda Hiroshi、Iwata Nobuhisa、Ueda Tomoya、Seno Ayako、Nishida Taku、Soeda Tsunenari、Okayama Satoshi、Watanabe Makoto、Kawakami Rika、Saito Yoshihiko
- Journal Title
  
  Hypertension
  
  Volume: 77 Issue: 6 Pages: 1931-1939
- DOI
  10.1161/hypertensionaha.120.16445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15898, KAKENHI-PROJECT-20K08414, KAKENHI-PROJECT-18J02247
[Journal Article] Salt accelerates aldosterone-induced cardiac remodeling in the absence of guanylyl cyclase-A signaling.2016
- Author(s)
  Nakagawa H, Somekawa S, Onoue K, Kumazawa T, Ueda T, Seno A, Nakada Y, Nakano T, Matsui M, Soeda T, Okayama S, Kawakami R, Kawata H, Okura H, Saito Y.
- Journal Title
  
  Life Sciences
  
  Volume: 165 Pages: 9-15
- DOI
  10.1016/j.lfs.2016.09.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19392
[Presentation] Impairment of Cardiac cGMP Exacerbates Hypertensive Cardiac Remodeling2021
- Author(s)
  Hitoshi Nakagawa
- Organizer
  第85回　日本循環器学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15898
[Presentation] Cardiac Neprilysin Plays an Important Role in Hypertensive Cardiac Remodeling2021
- Author(s)
  Hitoshi Nakagawa
- Organizer
  第85回　日本循環器学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15898
[Presentation] Regulatory Effect of Neprilysin on cGMP Plays an Important Role in Cardiac Remodeling2019
- Author(s)
  Hitoshi Nakagawa, Takuya Kumazawa, Yuko Yoshioka, Tomoko Ioka, Yasuki Nakada, Tomoya Nakano, Satomi ISHIHARA, Naoto Minamino*, Nobuhisa Iwata**, Kenji Onoue Yoshihiko Saito
- Organizer
  第36回国際心臓病研究会日本部会 (ISHR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15898
[Presentation] Neprilysin Plays an Important Role in Regulation of Cardiac cGMP2019
- Author(s)
  Hitoshi Nakagawa, Takuya Kumazawa, Yuko Yoshioka, Tomoko Ioka, Yasuki Nakada, Tomoya Nakano, Satomi ISHIHARA, Naoto Minamino*, Nobuhisa Iwata**, Kenji Onoue Yoshihiko Saito
- Organizer
  日本循環器学会基礎フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15898
[Presentation] Local Action of Neprilysin Exacerbates Hypertensive Cardiac Remodeling2019
- Author(s)
  Hitoshi Nakagawa, Takuya Kumazawa, Kenji Onoue, Yasuki Nakada, Tomoya Nakano, Satomi Ishihara, Naoto Minamino*, Hiroshi Hosoda*, Nobuhisa Iwata**, Tomoya Ueda, Tsunenari Soeda, Makoto Watanabe, Rika Kawakami, Yoshihiko Saito
- Organizer
  American Heart Association Scientific Sessions (AHA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15898
[Presentation] Guanylyl Cyclase-A Signaling Attenuates Deleterious Salt effect on Aldosterone-Induced Cardiac Remodeling2016
- Author(s)
  H. Nakagawa
- Organizer
  XXII ISHR World Congress
- Place of Presentation
  ブエノスアイレス　アルゼンチン
- Year and Date
  2016-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19392
[Presentation] Natriuretic peptides regulate sympathetic nervous activity independent of mineralocorticoid receptor2015
- Author(s)
  中川　仁
- Organizer
  The 7th international conference on cGMP
- Place of Presentation
  トリアー　ドイツ
- Year and Date
  2015-06-19
- Data Source
  KAKENHI-PROJECT-15K19392

1. Okayama Satoshi (40445052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 岡本恵介 (90745423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 彦惣俊吾 (30423164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 斎藤能彦 (30250260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 野木一孝 (30867396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中田康紀 (70812379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 上田友哉 (80755538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 尾上健児 (90510173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nakagawa Hitoshi 中川 仁

Research Projects

Research Products

Co-Researchers

左室駆出率の保たれた心不全の心臓ミネラルコルチコイド受容体へのSGLT2の作用の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of pathophysiology and novel therapeutic target in heart failure with preserved ejection fraction focused on SGLT2.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ネプリライシンの心不全改善効果に寄与する基質の優位性の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

収縮性の保持された心不全の発症・進展機序の解明に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cardiac Neprilysin Plays an Important Role in Hypertensive Cardiac RemodelingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The inhibitory effect of ANP on sympathetic nervous activity via mineralocorticoid receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research to build a system to support decisions on end-of-life care of patients with cardiovascular diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Roles of Natriuretic Peptides and the Significance of Neprilysin in Cardiovascular Diseases2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Local Action of Neprilysin Exacerbates Pressure Overload Induced Cardiac Remodeling2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Salt accelerates aldosterone-induced cardiac remodeling in the absence of guanylyl cyclase-A signaling.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Impairment of Cardiac cGMP Exacerbates Hypertensive Cardiac Remodeling2021

Author(s)

Organizer

Data Source

[Presentation] Cardiac Neprilysin Plays an Important Role in Hypertensive Cardiac Remodeling2021

Author(s)

Organizer

Data Source

[Presentation] Regulatory Effect of Neprilysin on cGMP Plays an Important Role in Cardiac Remodeling2019

Author(s)

Organizer

Data Source

[Presentation] Neprilysin Plays an Important Role in Regulation of Cardiac cGMP2019

Author(s)

Organizer

Data Source

[Presentation] Local Action of Neprilysin Exacerbates Hypertensive Cardiac Remodeling2019

Author(s)

Organizer

Nakagawa Hitoshi 中川仁