Horie Takahiro 堀江貴裕

… Alternative Names

HORIE Takahiro 堀江貴裕

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Researcher Number	20565577
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2024: 京都大学, 医学研究科, 講師 2016 – 2023: 京都大学, 医学研究科, 助教 2012 – 2016: 京都大学, 医学(系)研究科(研究院), 助教 2013: 京都大学, 大学院・医学研究科循環器内科 2010 – 2011: 京都大学, 医学研究科, 特定助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Circulatory organs internal medicine / Metabolomics / Cardiovascular medicine Except Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine / Circulatory organs internal medicine
Keywords	Principal Investigator 動脈硬化 / マイクロRNA / コレステロール / ノンコーディングRNA / 非コードRNA / SREBP / 脂質代謝 / HDL / 褐色脂肪細胞 / 肥満 … More / 心血管代謝性疾患 / トランスレーショナルリサーチ / 脂質 / 内科 / 治療応用 / microRNA / NASH / 脂肪酸 / 非アルコール性脂肪肝炎 / ドキソルビシン / 心不全 … More Except Principal Investigator マイクロRNA / 動脈硬化 / コレステロール / 線維化 / 心肥大 / HDL-C / シングルセル解析 / 大動脈瘤 / 非アルコール性脂肪肝炎 / 非コードRNA / 心不全 / iPSC / 代謝 / 人工核酸 / 核酸医薬 / iPS細胞 / 骨髄 / 慢性炎症 / 炎症 / ナノ粒子 / 動脈瘤 / 脂肪肝 / SREBP-1 / SREBP-2 / ABCA1 Less

非コードRNAによる褐色脂肪細胞・ベージュ脂肪細胞の活性化機構の解明Principal Investigator
- Principal Investigator
  
  堀江貴裕
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kyoto University
Elucidation of the pathophysiology of aortic aneurysms and development of novel therapeutic agents to inhibit their progression and promote their regression
- Principal Investigator
  
  尾野亘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyoto University
Elucidation of the functions of long non-coding RNA in cardiovascular diseases
- Principal Investigator
  
  Ono Koh
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyoto University
Functional analysis of cholesterol-related long non-coding RNAs and their clinical applicationPrincipal Investigator
- Principal Investigator
  
  Horie Takahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kyoto University
Investigation of the role of microRNAs in the formation of liver fibrosisPrincipal Investigator
- Principal Investigator
  
  Takahiro Horie
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
Elucidation of global metabolic control mechanisms by microRNA-33a/b and development of specific regulatory strategy using artificial nucleic acid
- Principal Investigator
  
  Ono Koh
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyoto University
Elucidation of the functions of microRNA-33 in homeostasis in vivo
- Principal Investigator
  
  Ono Koh
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyoto University
Elucidation of the regulatory mechanism of lipid metabolism by intronic microRNA-33a, -33bPrincipal Investigator
- Principal Investigator
  
  HORIE TAKAHIRO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyoto University
Investigation of the novel prevention and treatment for atherosclerosis by microRNA modulationPrincipal Investigator
- Principal Investigator
  
  HORIE TAKAHIRO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyoto University
Elucidation of the functions of miR-33a/b in cholesterol homeostasis
- Principal Investigator
  
  ONO KOH
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyoto University
Elucidation of the function of microRNAs on cardiovascular and metabolic disease : Investigation for a novel therapy by regulating microRNAsPrincipal Investigator
- Principal Investigator
  
  HORIE Takahiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyoto University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book Patent

[Book] マイクロRNA-33の動脈硬化形成における機能・役割について
- Author(s)
  堀江貴裕
- Publisher
  Asahi Medical
- Data Source
  KAKENHI-PROJECT-24790753
[Journal Article] MicroRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity.2021
- Author(s)
  Horie T, Nakao T, Miyasaka Y, Nishino T, Matsumura S, Nakazeki F, Ide Y, Kimura M, Tsuji S, Ruiz Rodriguez R, WatanabeT, Yamasaki T, Xu S, Otani C, Miyagawa S, Matsushita K, Sowa N, Omori A, Tanaka J, Nishimura C, Picciotto MR, Inoue H, Watanabe D, Nakamura K, Sasaki T, Kimura T, Ono K, et al.
- Journal Title
  
  Nat Commun.
  
  Volume: 12 Issue: 1 Pages: 843-843
- DOI
  10.1038/s41467-021-21107-5
- NAID
  120006958077
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08904, KAKENHI-PROJECT-18H04014, KAKENHI-PROJECT-18H02717, KAKENHI-PROJECT-18K18452, KAKENHI-PROJECT-20H03418, KAKENHI-PROJECT-20K21600
[Journal Article] Homeobox A4 suppresses vascular remodeling by repressing YAP/TEAD transcriptional activity.2020
- Author(s)
  Kimura M, Horie T, Baba O, Ide Y, Tsuji S, Ruiz Rodriguez R, Watanabe T, Yamasaki T, Otani C, Xu S, Miyasaka Y, Nakashima Y, Kimura T, Ono K.
- Journal Title
  
  EMBO Reports
  
  Volume: 21 Issue: 4
- DOI
  10.15252/embr.201948389
- NAID
  120006936405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08556, KAKENHI-PROJECT-20K08904, KAKENHI-PROJECT-20K21600, KAKENHI-PROJECT-17H04177
[Journal Article] Functional Non-coding RNAs in Vascular Diseases.2020
- Author(s)
  Ono K, Horie T, Baba O, Kimura M, Tsuji S, Ruiz Rodriguez R, Sawa M, Kimura T.
- Journal Title
  
  FEBS Lett.
  
  Volume: in press Issue: 22 Pages: 6315-6330
- DOI
  10.1111/febs.15678
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08904, KAKENHI-PROJECT-20K21600
[Journal Article] ABLE-MET Investigators. Effects of Metformin on Left Ventricular Size and Function in Hypertensive Patients with Type 2 Diabetes Mellitus: Results of a Randomized, Controlled, Multicenter, Phase IV Trial.2020
- Author(s)
  Ono K, Wada H, Satoh-Asahara N, Inoue H, Uehara K, Funada J, Ogo A, Horie T, Fujita M, Shimatsu A, Hasegawa K.
- Journal Title
  
  Am J Cardiovasc Drugs.
  
  Volume: 20 Issue: 3 Pages: 283-293
- DOI
  10.1007/s40256-019-00381-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08904, KAKENHI-PROJECT-17K09860, KAKENHI-PROJECT-17H04177
[Journal Article] Utility of collagen-derived peptides as markers of organ injury in patients with acute heart failure.2020
- Author(s)
  Nagao K, Tamura A, Sato Y, Hata R, Kawase Y, Kadota K, Horie T, Sowa N, Nishiga M, Ono K, Inada T, Tanaka M.
- Journal Title
  
  Open Heart
  
  Volume: 7 Issue: 1 Pages: e001041-e001041
- DOI
  10.1136/openhrt-2019-001041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08904
[Journal Article] LincRNA alleviates cardiac systolic dysfunction under pressure overload.2020
- Author(s)
  Kuwabara Y, Tsuji S, Nishiga M, Izuhara M, Ito S, Nagao K, Horie T, Watanabe S, Koyama S, Kiryu H, Nakashima Y, Baba O, Nakao T, Nishino T, Sowa N, Miyasaka Y, Hatani T, Ide Y, Nakazeki F, Kimura M, Yoshida Y, Inada T, Kimura T, Ono K.
- Journal Title
  
  Commun Biol.
  
  Volume: 3 Issue: 1 Pages: 434-434
- DOI
  10.1038/s42003-020-01164-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08904, KAKENHI-PROJECT-18J20214, KAKENHI-PROJECT-17K00398, KAKENHI-PROJECT-20K21600, KAKENHI-PROJECT-17H04176
[Journal Article] The identification of differential roles of microRNA-33a and -33b during atherosclerosis progression with genetically modified mice.2019
- Author(s)
  Koyama S, Horie T, Nishino T, Baba O, Sowa N, Miyasaka Y, Kuwabara Y, Nakao T, Nishiga M, Nishi H, Nakashima Y, Nakazeki F, Ide Y, Kimura M, Tsuji S, Rodriguez RR, Xu S, Yamasaki T, Otani C, Watanabe T, Nakamura T, Hasegawa K, Kimura T, Ono K.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 8(13) Issue: 13
- DOI
  10.1161/jaha.119.012609
- NAID
  120006818702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09860, KAKENHI-PROJECT-17H04177
[Journal Article] MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons2019
- Author(s)
  Nakazeki F、Tsuge I、Horie T、Imamura K、Tsukita K、Hotta A、Baba O、Kuwabara Y、Nishino T、Nakao T、Nishiga M、Nishi H、Nakashima Y、Ide Y、Koyama S、Kimura M、Tsuji S、Naitoh M、Suzuki S、Izumi Y、Kawarai T、Kaji R、Kimura T、Inoue H、Ono K
- Journal Title
  
  Clinical Science
  
  Volume: 133 Issue: 4 Pages: 583-595
- DOI
  10.1042/cs20180980
- NAID
  120006937614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16002, KAKENHI-PUBLICLY-17H05599, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17K19590, KAKENHI-PROJECT-17K09860
[Journal Article] Cardioprotective Effects of VCP?Modulator KUS121 in Murine and Porcine Models of Myocardial Infarction2019
- Author(s)
  Ide Yuya, at al.
- Journal Title
  
  JACC: Basic to Translational Science
  
  Volume: 4 Issue: 6 Pages: 701-714
- DOI
  10.1016/j.jacbts.2019.06.001
- NAID
  120006734885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15888, KAKENHI-PROJECT-19H03435, KAKENHI-PROJECT-17K09860, KAKENHI-PROJECT-17H04177
[Journal Article] SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo2018
- Author(s)
  Nishino T、Horie T、Baba O、Sowa N、Hanada R、Kuwabara Y、Nakao T、Nishiga M、Nishi H、Nakashima Y、Nakazeki F、Ide Y、Koyama S、Kimura M、Nagata M、Yoshida K、Takagi Y、Nakamura T、Hasegawa K、Miyamoto S、Kimura T、Ono K.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 10 Pages: 2460-2473
- DOI
  10.1161/atvbaha.118.311409
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-17K16002, KAKENHI-PUBLICLY-17H05599, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17K19590, KAKENHI-PROJECT-17K09860
[Journal Article] Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction2018
- Author(s)
  Hakuno Daihiko、Kimura Masahiro、Ito Shinji、Satoh Junko、Nakashima Yasuhiro、Horie Takahiro、Kuwabara Yasuhide、Nishiga Masataka、Ide Yuya、Baba Osamu、Nishi Hitoo、Nakao Tetsushi、Nishino Tomohiro、Nakazeki Fumiko、Koyama Satoshi、Hanada Ritsuko、Randolph Ruiz R.、Endo Jin、Kimura Takeshi、Ono Koh
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1-17
- DOI
  10.1038/s41598-018-35194-w
- NAID
  120006645320
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16002, KAKENHI-PUBLICLY-17H05599, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17K19590, KAKENHI-PROJECT-17K09860
[Journal Article] Long Non-Coding RNAs as Key Regulators of Cardiovascular Diseases2018
- Author(s)
  Ono K, Kuwabara Y, Horie T, Kimura T.
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 5 Pages: 1231-1236
- DOI
  10.1253/circj.CJ-18-0169
- NAID
  130006725985
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-17H04177, KAKENHI-PUBLICLY-17H05599, KAKENHI-PROJECT-17K19590, KAKENHI-PROJECT-17K09860
[Journal Article] Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo2018
- Author(s)
  Nakazeki Fumiko、Nishiga Masataka、Horie Takahiro、Nishi Hitoo、Nakashima Yasuhiro、Baba Osamu、Kuwabara Yasuhide、Nishino Tomohiro、Nakao Tetsushi、Ide Yuya、Koyama Satoshi、Kimura Masahiro、Tsuji Shuhei、Sowa Naoya、Yoshida Shigeo、Conway Simon J.、Yanagita Motoko、Kimura Takeshi、Ono Koh
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8553-8553
- DOI
  10.1038/s41598-018-27009-9
- NAID
  120006510274
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04673, KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-17K16002, KAKENHI-PUBLICLY-17H05599, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17K19590, KAKENHI-PROJECT-17K09860
[Journal Article] MicroRNA-33 regulates the population of peripheral inflammatory Ly6Chigh monocytes through dual pathways.2018
- Author(s)
  Baba O, Horie T, Hakuno D, Nakashima Y, Nishi H, Kuwabara Y, Nakao T, Nishiga M, Nishino T, Ide Y, Nakazeki F, Koyama S, Kimura M, Hanada R, Kawahara M, Kimura T, and Ono K.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 38 Issue: 14 Pages: 1-17
- DOI
  10.1128/mcb.00604-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09846, KAKENHI-PROJECT-17K16002, KAKENHI-PUBLICLY-17H05599, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17K19590, KAKENHI-PROJECT-17K09860
[Journal Article] Circulating markers of collagen types I, III, and IV in patients with dilated cardiomyopathy: relationships with myocardial collagen expression2018
- Author(s)
  Nagao Kazuya、Inada Tsukasa、Tamura Akinori、Kajitani Kenji、Shimamura Kiyotaka、Yukawa Hiroshi、Aida Kenji、Sowa Naoya、Nishiga Masataka、Horie Takahiro、Makita Toshinori、Ono Koh、Tanaka Masaru
- Journal Title
  
  ESC Heart Failure
  
  Volume: 5 Issue: 6 Pages: 1044-1051
- DOI
  10.1002/ehf2.12360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05599, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17K19590, KAKENHI-PROJECT-17K09860
[Journal Article] Dynamic changes of serum microRNA-122-5p through therapeutic courses indicates amelioration of acute liver injury accompanied by acute cardiac decompensation.2017
- Author(s)
  Satoshi Koyama, Takashi Kuragaichi, Yukihito Sato, Yasuhide Kuwabara, Shunsuke Usami, Takahiro Horie, Osamu Baba, Daihiko Hakuno, Yasuhiro Nakashima, Tomohiro Nishino, Masataka Nishiga, Tetsushi Nakao, Hidenori Arai, Takeshi Kimura, Koh Ono
- Journal Title
  
  ESC Heart Failure
  
  Volume: 4 Issue: 2 Pages: 112-121
- DOI
  10.1002/ehf2.12123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15J00784, KAKENHI-PROJECT-14J05148, KAKENHI-PROJECT-16K09497, KAKENHI-PROJECT-17K09860, KAKENHI-PROJECT-17H04177, KAKENHI-PUBLICLY-17H05599
[Journal Article] Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways.2017
- Author(s)
  Nakao T, Horie T, Baba O, Nishiga M, Nishino T, Izuhara M, Kuwabara Y, Nishi H, Usami S, Nakazeki F, Ide Y, Koyama S, Kimura M, Sowa N, Ohno S, Aoki H, Hasegawa K, Sakamoto K, Minatoya K, Kimura T, Ono K.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 37 Issue: 11 Pages: 2161-2170
- DOI
  10.1161/atvbaha.117.309768
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09860, KAKENHI-PROJECT-17K16002, KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-16H05428, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-15K10249, KAKENHI-PROJECT-17K19590, KAKENHI-PUBLICLY-17H05599
[Journal Article] Ad hoc vs. Non-ad hoc Percutaneous Coronary Intervention Strategies in Patients With Stable Coronary Artery Disease2017
- Author(s)
  Toyota T, Horie M, et al.
- Journal Title
  
  Circ J
  
  Volume: 81 Issue: 4 Pages: 458-467
- DOI
  10.1253/circj.CJ-16-0987
- NAID
  130005475829
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-26293186
[Journal Article] on behalf of the CREDO-Kyoto PCI/CABG Registry Cohort-2 Investigators. Single-session Versus Staged Procedures for Elective Multi-vessel Percutaneous Coronary Intervention.2017
- Author(s)
  Toyota T, Morimoto T, Shiomi H, Yamaji K, Ando K, Ono K, Shizuta S, Saito N, Kato T, Kaji S, Furukawa Y, Nakagawa Y, Kadota K, Horie M, Kimura T,
- Journal Title
  
  Heart.
  
  Volume: Nov 16. Issue: 11 Pages: 936-944
- DOI
  10.1136/heartjnl-2017-312117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K04790, KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-17H04177
[Journal Article] Prevention of neointimal formation using miRNA-126-containing nanoparticle-conjugated stents in a rabbit model.2017
- Author(s)
  Izuhara M, Kuwabara Y, Saito N, Yamamoto E, Hakuno D, Nakashima Y, Horie T, Baba O, Nishiga M, Nakao T, Nishino T, Nakazeki F, Ide Y, Kimura M, Kimura T, Ono K.
- Journal Title
  
  PLoS One
  
  Volume: 12(3) Issue: 3 Pages: e0172798-e0172798
- DOI
  10.1371/journal.pone.0172798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J05148, KAKENHI-PROJECT-26293186, KAKENHI-PROJECT-26461144, KAKENHI-PROJECT-16K09497, KAKENHI-PROJECT-16K19400, KAKENHI-PROJECT-17K09860, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17K19590, KAKENHI-PUBLICLY-17H05599
[Journal Article] Incidence and Prognostic Impact of Heart Failure Hospitalization During Follow-up after Primary Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction.2017
- Author(s)
  Taniguchi T, Horie M, et al.
- Journal Title
  
  American Journal of Cardiology
  
  Volume: 印刷中 Issue: 11 Pages: 1729-1739
- DOI
  10.1016/j.amjcard.2017.03.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-26293186, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17H04177
[Journal Article] Development of a Patient-Derived Induced Pluripotent Stem Cell Model for the Investigation of <i>SCN5A</i>-D1275N-Related Cardiac Sodium Channelopathy2017
- Author(s)
  Hayano M, Makiyama T
- Journal Title
  
  Circ J
  
  Volume: 81 Issue: 12 Pages: 1783-1791
- DOI
  10.1253/circj.CJ-17-0064
- NAID
  130006219109
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09499, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17K09860, KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17H06806
[Journal Article] Emerging Novel Biomarkers for Arteriosclerosis Obliterans2016
- Author(s)
  Horie T, Kimura T, Ono K.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 23 Issue: 2 Pages: 171-172
- DOI
  10.5551/jat.ED028
- NAID
  130005122030
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461144, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-26293186
[Journal Article] MicroRNA-33 Controls Adaptive Fibrotic Response in the Remodeling Heart by Preserving Lipid Raft Cholesterol.2016
- Author(s)
  Nishiga M, Horie T, Kuwabara Y, Nagao K, Baba O, Nakao T, Nishino T, Hakuno D, Nakashima Y, Nishi H, Nakazeki F, Ide Y, Koyama S, Kimura M, Hanada R, Nakamura T, Inada T, Hasegawa K, Conway SJ, Kita T, Kimura T, Ono K.
- Journal Title
  
  Circ Res.
  
  Volume: - Issue: 5 Pages: 835-847
- DOI
  10.1161/circresaha.116.309528
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-16H06900, KAKENHI-PROJECT-14J05148, KAKENHI-PROJECT-26293186, KAKENHI-PROJECT-26461144, KAKENHI-PROJECT-16K09497, KAKENHI-PROJECT-16K19400, KAKENHI-PROJECT-17K09860, KAKENHI-PROJECT-17K19534, KAKENHI-PROJECT-16H05145, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-15K09108, KAKENHI-PROJECT-17K19590, KAKENHI-PUBLICLY-17H05599
[Journal Article] MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development.2016
- Author(s)
  Eso Y, Takai A, Matsumoto T, Inuzuka T, Horie T, Ono K, Uemoto S, Lee K, Edelmann W, Chiba T, Marusawa H.
- Journal Title
  
  Cancer Research
  
  Volume: 76 Issue: 15 Pages: 4383-93
- DOI
  10.1158/0008-5472.can-15-2926
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J11897, KAKENHI-PROJECT-26293186, KAKENHI-PROJECT-26461144
[Journal Article] MicroRNA-451 exacerbates lipotoxicity in cardiac myocytes and high-fat diet-induced cardiac hypertrophy in mice through suppression of the LKB1/AMPK pathway.2015
- Author(s)
  Kuwabara Y, Horie T, Baba O, Watanabe S, Nishiga M, Usami S, Izuhara M, Nakao T, Nishino T, Otsu K, Kita T, Kimura T, Ono K.
- Journal Title
  
  Circulation Research
  
  Volume: 116 Issue: 2 Pages: 279-288
- DOI
  10.1161/circresaha.116.304707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J05148, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25670383, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-26293186, KAKENHI-PROJECT-26461144, KAKENHI-PROJECT-26860556
[Journal Article] High-density lipoprotein cholesterol levels and cardiovascular outcomes in Japanese patients after percutaneous coronary intervention: a report from the CREDO-Kyoto registry cohort-2.2015
- Author(s)
  Izuhara M, Ono K, Shiomi H, Morimoto T, Furukawa Y, Nakagawa Y, Shizuta S, Tada T, Tazaki J, Horie T, Kuwabara Y, Baba O, Nishino T, Kita T, Kimura T; CREDO-Kyoto PCI/CABG Registry Cohort-2 Investigators.
- Journal Title
  
  Atherosclerosis.
  
  Volume: 242(2) Issue: 2 Pages: 632-8
- DOI
  10.1016/j.atherosclerosis.2015.05.010
- NAID
  120005678183
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461144, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-14J05148, KAKENHI-PROJECT-26860556, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-26293186
[Journal Article] – Novel “Thrifty” Models –2015
- Author(s)
  Ono K, Horie T, Nishino T, Baba O, Kuwabara Y, Yokode M, Kita T, Kimura T.
- Journal Title
  
  Circ J
  
  Volume: 79 Issue: 2 Pages: 278-284
- DOI
  10.1253/circj.CJ-14-1252
- NAID
  130004927073
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J05148, KAKENHI-PROJECT-25670383, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-26293186, KAKENHI-PROJECT-26860556, KAKENHI-PROJECT-26461144, KAKENHI-PROJECT-25293182
[Journal Article] Expression Patterns of miRNA-423-5p in the Serum and Pericardial Fluid in Patients Undergoing Cardiac Surgery.2015
- Author(s)
  Miyamoto S, Usami S, Kuwabara Y, Horie T, Baba O, Hakuno D, Nakashima Y, Nishiga M, Izuhara M, Nakao T, Nishino T, Ide Y, Nakazeki F, Wang J, Ueyama K, Kimura T, Ono K.
- Journal Title
  
  PLoS One.
  
  Volume: 10(11) Issue: 11 Pages: e0142904-e0142904
- DOI
  10.1371/journal.pone.0142904
- NAID
  120005749912
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461144, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-26893124, KAKENHI-PROJECT-14J05148, KAKENHI-PROJECT-26860556, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-26293186
[Journal Article] microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain.2015
- Author(s)
  Kim J, Yoon H, Horie T, Burchett JM, Restivo JL, Rotllan N, Ramírez CM, Verghese PB, Ihara M, Hoe HS, Esau C, Fernández-Hernando C, Holtzman DM, Cirrito JR, Ono K, Kim J.
- Journal Title
  
  J Neurosci.
  
  Volume: 35(44) Issue: 44 Pages: 14717-26
- DOI
  10.1523/jneurosci.2053-15.2015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461144, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26293186
[Journal Article] MicroRNAs and High-Density Lipoprotein Cholesterol Metabolism.2015
- Author(s)
  Ono K, Horie T, Nishino T, Baba O, Kuwabara Y, Kimura T.
- Journal Title
  
  Int Heart J.
  
  Volume: 56 Pages: 365-71
- NAID
  130005087574
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293186
[Journal Article] MicroRNAs and High-Density Lipoprotein Cholesterol Metabolism2015
- Author(s)
  Ono K, Horie T, Nishino T, Baba O, Kuwabara Y, Kimura T.
- Journal Title
  
  Int. Heart J.
  
  Volume: 56 Issue: 4 Pages: 365-371
- DOI
  10.1536/ihj.15-019
- NAID
  130005087574
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461144, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-14J05148, KAKENHI-PROJECT-26860556
[Journal Article] Cardiac-Specific Inhibition of Kinase Activity in Calcium/Calmodulin-Dependent Protein Kinase Kinase-β Leads to Accelerated Left Ventricular Remodeling and Heart Failure after Transverse Aortic Constriction in Mice2014
- Author(s)
  Shin Watanabe, Takahiro Horie, Kazuya Nagao, Yasuhide Kuwabara, Osamu Baba, Hitoo Nishi, Naoya Sowa, Michiko Narazaki, Tetsuya Matsuda, Genzou Takemura, Hiromichi Wada, Koji Hasegawa, Takeshi Kimura, Koh Ono
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 9 Pages: e108201-e108201
- DOI
  10.1371/journal.pone.0108201
- NAID
  120005496630
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300161, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25670383, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-26293186, KAKENHI-PROJECT-26461144, KAKENHI-PROJECT-26860556
[Journal Article] Effect of Pre-infarction Angina Pectoris on Long-term Survival in Patients with ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention2014
- Author(s)
  Taniguchi T, Shiomi H, Toyota T, Morimoto T, Akao M, Nakatsuma K, Ono K, Makiyama T, Shizuta S, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Horie M, Kimura T.
- Journal Title
  
  Am J Cardiol
  
  Volume: 114 Issue: 8 Pages: 1179-1186
- DOI
  10.1016/j.amjcard.2014.07.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24531210, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25670383, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-26293186
[Journal Article] MicroRNAs and lipoprotein metabolism2014
- Author(s)
  Horie-T, Baba-O, Kuwabara-Y, Yokode-M, Kita-T, Kimura-T, Ono-K
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 21 Pages: 17-22
- NAID
  130004845461
- URL
  https://www.jstage.jst.go.jp/articla/jat/21/1/21_20859/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790753
[Journal Article] MicroRNAs and lipoprotein metabolism2014
- Author(s)
  Horie T, Baba O, Kuwabara Y, Yokode M, Kita T, Kimura T, and Ono K
- Journal Title
  
  J of Atherosclerosis and Thrombosis
  
  Volume: 21 Pages: 17-22
- NAID
  130004845461
- URL
  https://www.jstage.jst.go.jp/article/jat/21/1/21_20859/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390211
[Journal Article] MicroRNAs and lipoprotein metabolism.2014
- Author(s)
  Horie-T, Baba-O, Kuwabara-Y, Yokode-M, Kita-T, Kimura-T, Ono-K
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 21 Pages: 17-22
- NAID
  130004845461
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461144
[Journal Article] MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo.2014
- Author(s)
  Horie T, Nishino T, Baba O, Kuwabara Y, Nakao T, Nishiga M, Usami S, Izuhara M, Nakazeki F, Ide Y, Koyama S, Sowa N, Yahagi N, Shimano H, Nakamura T, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T, Ono K.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 5312-5312
- DOI
  10.1038/srep05312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J05148, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25461369, KAKENHI-PROJECT-25670383, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-26461144, KAKENHI-PROJECT-26670147, KAKENHI-PROJECT-26670448, KAKENHI-PROJECT-26860556, KAKENHI-PLANNED-23116006
[Journal Article] MicroRNAs and lipoprotein metabolism2014
- Author(s)
  1: Horie-T, Baba-O, Kuwabara-Y, Yokode-M, Kita-T, Kimura-T, Ono-K
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: ２１ Pages: 17-22
- NAID
  130004845461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790753
[Journal Article] MicroRNAs and lipoprotein metabolism.2014
- Author(s)
  1: Horie-T, Baba-O, Kuwabara-Y, Yokode-M, Kita-T, Kimura-T, Ono-K
- Journal Title
  
  J of Atherosclerosis and Thrombosis
  
  Volume: 21 Pages: 17-22
- NAID
  130004845461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390211
[Journal Article] マイクロRNA-33の動脈硬化形成における機能・役割について2013
- Author(s)
  堀江貴裕
- Journal Title
  
  Asahi Medical
  
  Volume: 42巻12号 Pages: 36-37
- Data Source
  KAKENHI-PROJECT-24790753
[Journal Article] MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice.2013
- Author(s)
  Horie T, Nishino T, Baba O, Kuwabara Y, Nakao T, Nishiga M, Usami S, Izuhara M, Sowa N, Yahagi N, Shimano H, Matsumura S, Inoue K, Marusawa H, Nakamura T, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T, Ono K
- Journal Title
  
  Nat Commun.
  
  Volume: 4:2883 Issue: 1 Pages: 2883-2883
- DOI
  10.1038/ncomms3883
- NAID
  120005349007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23390211, KAKENHI-PUBLICLY-24116512, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24790753, KAKENHI-PROJECT-24890094, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25461369, KAKENHI-PROJECT-25462136, KAKENHI-PROJECT-25670383
[Journal Article] Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts2013
- Author(s)
  Tamaki Y, Iwanaga Y, Niizuma S, Kawashima T, Kato T, Inuzuka Y, Horie T, Morooka H, Takase T, Akahashi Y, Kobuke K, Ono K, Shioi T, Sheikh SP, Ambartsumian N, Lukanidin E, Koshimizu TA, Miyazaki S, Kimura T
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 57 Pages: 72-81
- DOI
  10.1016/j.yjmcc.2013.01.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390211, KAKENHI-PROJECT-23659469, KAKENHI-PUBLICLY-24116512, KAKENHI-PROJECT-24590327, KAKENHI-PROJECT-24591094, KAKENHI-PROJECT-24790753, KAKENHI-PROJECT-24790790, KAKENHI-PUBLICLY-25136709, KAKENHI-PROJECT-25462136, KAKENHI-PROJECT-25670383
[Journal Article] Roles of MicroRNAs and Myocardial Cell Differentiation2012
- Author(s)
  Takaya T, Nishi H, Horie T, Ono K, Hasegawa K
- Journal Title
  
  Prog Mol Biol Transl Sci
  
  Volume: 111 Pages: 139-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790753
[Journal Article] MicroRNA 26b Encoded by the Intron of Small CTD Phosphatase (SCP) 1 Has an Antagonistic Effect on its Host Gene2012
- Author(s)
  Sowa N, Horie T, Kuwabara Y, Baba O, Watanabe S, Nishi H, Kinoshita M, Takanabe-Mori R, Wada H, Shimatsu A, Hasegawa K, Kimura T, and Ono K
- Journal Title
  
  Journal ofCellular Biochem.
  
  Volume: 113 Issue: 11 Pages: 3455-65
- DOI
  10.1002/jcb.24222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390211, KAKENHI-PROJECT-23659469, KAKENHI-PROJECT-24790753, KAKENHI-PUBLICLY-24116512
[Journal Article] Roles of micro RNAs and myocardial cell differentiation.2012
- Author(s)
  Takaya T, Nishi H, Horie T, Ono K, Hasegawa K.
- Journal Title
  
  Prog Mol Biol Transl Sci
  
  Volume: 111 Pages: 139-152
- DOI
  10.1016/b978-0-12-398459-3.00006-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790270, KAKENHI-PROJECT-24790753
[Journal Article] MicroRNA-33-deficiency reduces the progression of atherosclerotic plaque in apoE-/- mice2012
- Author(s)
  Horie T, Baba O, Kuwabara Y, Chujo Y, Watanabe S, Kinoshita M, Horiguchi M, Nakamura T, Chonabayashi K, Hishizawa M, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T, Ono K
- Journal Title
  
  JAm Heart Assoc
  
  Volume: 1 Issue: 6
- DOI
  10.1161/jaha.112.003376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390211, KAKENHI-PROJECT-23659469, KAKENHI-PROJECT-24790753, KAKENHI-PUBLICLY-24116512
[Journal Article] microRNA-33は生体内でHDLコレステロールを制御する2011
- Author(s)
  尾野亘、堀江貴裕、木村剛、北徹
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 575-578
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] MicroRNA-27a regulates beta cardiac myosin heavy chain gene expression by targeting thyroid hormone receptor beta 1 in neonatal rat ventricular myocytes.2011
- Author(s)
  Nishi-H
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 31 Issue: 4 Pages: 744-55
- DOI
  10.1128/mcb.00581-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390211
[Journal Article] micro RNA-33は生体内でHDLコレステロールを制御する2011
- Author(s)
  尾野亘、堀江貴裕、木村剛、北徹
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 575-578
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] Increased microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular disease indicate myocardial damage2011
- Author(s)
  Kuwabara Y, Ono K, Horie T, Nishi H, Nagao K, Kinoshita M, Watanabe S, Baba O, Kojima Y, Shizuta S, Imai M, Tamura T, Kita T, Kimura T
- Journal Title
  
  Circ Cardiovasc Genet
  
  Volume: 4 Issue: 4 Pages: 446-454
- DOI
  10.1161/circgenetics.110.958975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703, KAKENHI-PROJECT-23390211
[Journal Article] コレステロールホメオスターシスとマイクロRNA2011
- Author(s)
  堀江貴裕、尾野亘、横出正之、木村剛
- Journal Title
  
  血管医学
  
  Volume: 12 Pages: 39-46
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] Distinct characteristics of circulating vascular endothelial growth factor-A and C levels in human subjects2011
- Author(s)
  Wada H, Ura S, Kitaoka S, Satoh-Asahara N, Horie T, Ono K, Takaya T, Takanabe-Mori R, Akao M, Abe M, Morimoto T, Murayama T, Yokode M, Fujita M, Shimatsu A, Hasegawa K.
- Journal Title
  
  Pros ONE
  
  Volume: 6 Issue: 12 Pages: 29351-29351
- DOI
  10.1371/journal.pone.0029351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590592, KAKENHI-PROJECT-21590646, KAKENHI-PROJECT-21590918, KAKENHI-PROJECT-21590944, KAKENHI-PROJECT-22790703
[Journal Article] LOX-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice2010
- Author(s)
  Takanabe-Mori R, Ono K, Sowa N, Takaya T, Horie T, Satoh-Asahara N, ShimatsuA, Fujita M, Sawamura T, Hasegawa K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 398 Pages: 576-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] Acute Doxorubicin Cardiotoxicity Is Associated with miR-146a-induced Inhibition of the Neuregulin-ErbB Pathway2010
- Author(s)
  Horie T, Ono K, Nishi H, Nagao K, Kinoshita M, Watanabe S, Kuwabara Y, Nakashima Y, Takanabe-Mori R, Nishi E, Hasegawa K, Kita T, Kimura T.
- Journal Title
  
  Cardiovascular Res
  
  Volume: 87 Pages: 656-664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] Neural cell adhesion molecule is a cardio protective factor up-regulated by metabolic stress2010
- Author(s)
  Nagao K, Ono K, Iwanaga Y, Tamaki Y, Kojima Y, Horie T, Nishi H, Kinoshita M, Kuwabara Y, Hasegawa K, Kita T, Kimura T.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 48 Pages: 1157-68
- NAID
  120002381089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via ARL2 in neonatal rat cardiac myocytes.2010
- Author(s)
  Nishi H, Ono K, Iwanaga Y, Horie T, Nagao K, Takemura G, Kinoshita M, Kuwabara Y, Takanabe Mori R, Hasegawa K, Kita T, Kimura T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 4920-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] MicroRNA-33 encoded by an intron of Srebp2 regulates HDL in vivo2010
- Author(s)
  Horie T, Ono K, Horiguchi M, Nishi H, Nakamura T, Nagao K, Kinoshita M, Kuwabara Y, Marusawa H, Iwanaga Y, Hasegawa K, Yokode M, Kimura T, Kita T.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 107 Pages: 17321-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] LOX-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice.2010
- Author(s)
  Takanabe-Mori R, Ono K, Sowa N, Takaya T, Horie T, Satoh-Asahara N, Shimatsu A, Fujita M, Sawamura T, Hasegawa K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 398 Pages: 576-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] Regulation of adipocyte differentiation by activation of serotonin(5-HT) receptors 5-HT2AR and 5-HT2CR and involvement of microRNA-448-mediated repression of KLF52010
- Author(s)
  Kinoshita M, Ono K, Horie T, Nagao K, Nishi H, Kuwabara Y, Takanabe-Mori R, Hasegawa K, Kita T, and Kimura T.
- Journal Title
  
  Molecular Endocrinology
  
  Volume: 24 Pages: 1978-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] Regulation of adipocyte differentiation by activation of serotonin (5-HT) receptors 5-HT2AR and 5-HT2CR and involvement of microRNA-448-mediated repression of KLF5.2010
- Author(s)
  Kinoshita M, Ono K, Horie T, Nagao K, Nishi H, Kuwabara Y, Takanabe-Mori R, Hasegawa K, Kita T, Kimura T.
- Journal Title
  
  Molecular Endocrinology.
  
  Volume: 24 Pages: 1978-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] Neural cell adhesion molecule is a cardioprotective factor up-regulated by metabolic stress.2010
- Author(s)
  Nagao K, Ono K, Iwanaga Y, Tamaki Y, Kojima Y, Horie T, Nishi H, Kinoshita M, Kuwabara Y, Hasegawa K, Kita T, Kimura T
- Journal Title
  
  Journal of Molecular and Cellular Cardiology.
  
  Volume: 48 Pages: 1157-68
- NAID
  120002381089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via ARL2 in neonatal rat cardiac myocytes2010
- Author(s)
  Nishi H, Ono K, Iwanaga Y, Horie T, Nagao K, Takemura G, Kinoshita M, Kuwabara Y, Takanabe Mori R, Hasegawa K, Kita T, Kimura T.
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 4920-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Journal Article] Micro RNA-33 encoded by an intron of Srebp2 regulates HDL in vivo2010
- Author(s)
  Horie T, Ono K, Horiguchi M, Nishi H, Nakamura T, Nagao K, Kinoshita M, Kuwabara Y, Marusawa H, Iwanaga Y, Hasegawa K, Yokode M, Kimura T, Kita T
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 107 Pages: 17321-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790703
[Patent] NASHの予防及び/又は治療剤2021
- Inventor(s)
  尾野亘, 堀江貴裕, 西野共達, 宮川紗和, 小比賀聡, 笠原勇矢
- Industrial Property Rights Holder
  国立大学法人京都大学国立大学法人大阪大学国立研究開発法人医薬基盤・健康・栄養研究所
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-097796
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-17K09860
[Patent] ｍｉＲ－３３ｂ阻害物質による動脈瘤の予防または治療2020
- Inventor(s)
  尾野　亘、堀江貴裕、小山智史、山崎智弘
- Industrial Property Rights Holder
  尾野　亘、堀江貴裕、小山智史、山崎智弘
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-034619
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-17H04177
[Patent] 心筋細胞の保護用の医薬組成物2019
- Inventor(s)
  垣塚彰、尾野　亘、堀江貴裕、井手裕也、斉藤成達、木村剛
- Industrial Property Rights Holder
  垣塚彰、尾野　亘、堀江貴裕、井手裕也、斉藤成達、木村剛
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K09860
[Patent] microRNA（miR）-33aおよびmiR-33bを個別に制御できる合成核酸医薬の開発と大動脈瘤に対する効果2019
- Inventor(s)
  尾野　亘、堀江貴裕、西野共達、山崎智弘
- Industrial Property Rights Holder
  尾野　亘、堀江貴裕、西野共達、山崎智弘
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K09860
[Patent] miR-33bノックインマウスによる非アルコール性脂肪肝炎モデル2018
- Inventor(s)
  尾野　亘、堀江貴裕、西野共達
- Industrial Property Rights Holder
  尾野　亘、堀江貴裕、西野共達
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-17H04177
[Patent] 遺伝性痙性対麻痺(Hereditary Spastic Paraplegia; HSP)SPG4 に対するmicroRNA-33a抑制療法2018
- Inventor(s)
  尾野　亘、井上治久、今村恵子、堀江貴裕、中関典子
- Industrial Property Rights Holder
  尾野　亘、井上治久、今村恵子、堀江貴裕、中関典子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-119251
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H04177
[Patent] miR-33b ノックインマウスによる非アルコール性脂肪肝炎モデル2017
- Inventor(s)
  尾野　亘、堀江貴裕、西野共達
- Industrial Property Rights Holder
  尾野　亘、堀江貴裕、西野共達
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-059580
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K09860
[Patent] miR-33bノックインマウスによる非アルコール性脂肪肝炎モデル2017
- Inventor(s)
  尾野　亘、堀江貴裕、西野共達
- Industrial Property Rights Holder
  尾野　亘、堀江貴裕、西野共達
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-059580
- Filing Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] miR-33b has more impact on the formation of insulin resistance and atherosclerosis than miR-33a.2020
- Author(s)
  Takahiro Horie, Satoshi Koyama, Takeshi Kimura, Koh Ono
- Organizer
  第84回　日本循環器学会
- Data Source
  KAKENHI-PROJECT-20K08904
[Presentation] High-intensity statins work regardless of age. (Debate: Lipid Management: Is there Anything Beyond LDL?)2020
- Author(s)
  Takahiro Horie
- Organizer
  第84回　日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08904
[Presentation] The identification of differential roles of microRNA-33a and -33b during atherosclerosis progression with genetically modified mice.2019
- Author(s)
  Takahiro Horie, Satoshi Koyama, Takeshi Kimura, Koh Ono
- Organizer
  2019 XXIII ISHR WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] Identification of Differential Roles of Microrna-33a and -33b During Atherosclerosis Progression with Genetically Modified Mice2019
- Author(s)
  Takahiro Horie, Satoshi Koyama, Yui Miyasaka, Takeshi Kimura, Koh Ono
- Organizer
  ESC Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] MiR-33a は、SPG4 遺伝性痙性対麻痺における新規治療標的である2019
- Author(s)
  堀江貴裕、中関典子、津下到、今村恵子、木村剛、井上治久、尾野亘
- Organizer
  第56回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] Identification of Differential Roles of Microrna-33a and -33b During Atherosclerosis Progression with Genetically Modified Mice.2019
- Author(s)
  Takahiro Horie, Satoshi Koyama, Yui Miyasaka, Takeshi Kimura, Koh Ono
- Organizer
  Basic Cardiovascular Sciences Scientific Sessions 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] MiR-33a/b are a novel therapeutical target for vascular disease.2019
- Author(s)
  Takahiro Horie, Takeshi Kimura, Koh Ono
- Organizer
  第51回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] MicroRNA-33b promotes atherosclerotic plaque formation in Apoe-/- mice2018
- Author(s)
  Nishino T, Horie T, Baba O, Kuwabara Y, Hakuno D, Nakashima Y, Nakao T, Nishiga M, Kimura T, Ono K.
- Organizer
  第82回日本循環器学会
- Data Source
  KAKENHI-PROJECT-17H04177
[Presentation] Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo2018
- Author(s)
  Takahiro Horie、Fumiko Nakazeki、Takeshi Kimura、Koh Ono
- Organizer
  The 2nd JCS Council Forum on Basic CaridoVascular Research
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] Novel Long Intergenic Noncoding RNA, Lionheart, Guards the Heart from Pressure Overload2018
- Author(s)
  Kuwabara Y, Horie T, Baba O, Nishiga M, Nakao M, Nishino T, Nakazeki F, Koyama S, Kimura T, Ono K.
- Organizer
  第82回日本循環器学会
- Data Source
  KAKENHI-PROJECT-17H04177
[Presentation] SREBF1/MicroRNA-33b axis exhibits potent effect on　unstable atherosclerotic plaque formation in vivo2018
- Author(s)
  Takahiro Horie、Tomohito Nishino、Takeshi Kimura、Koh Ono
- Organizer
  The 2nd JCS Council Forum on Basic CaridoVascular Research
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo2018
- Author(s)
  Takahiro Horie, Fumiko Nakazeki, Masataka Nishiga, Takahiro Horie, Hitoo Nishi, Yasuhiro Nakashima, Osamu Baba, Yasuhide Kuwabara, Tomohiro Nishino, Tetsushi Nakao, Yuya Ide, Satoshi Koyama, Masahiro Kimura, Shuhei Tsuji, Naoya Sowa, Takeshi Kimura, and Koh Ono
- Organizer
  第50回日本動脈硬化学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] SREBF1/MicroRNA-33b axis exhibits potent effect on unstable atherosclerotic plaque formation in vivo2018
- Author(s)
  Takahiro Horie、Tomohiro Nishino、Tetsushi Nakao、Fumiko Nakazeki、Yuya Ide、Satoshi Koyama、Masahiro Kimura、Koji Hasegawa、Takeshi Kimura、Koh Ono
- Organizer
  Asian Pacific Society of Cardiology (APSC) Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] 動脈硬化性疾患に対する核酸医薬の可能性（シンポジウム 13 ：脂質異常症治療薬の新展開）2017
- Author(s)
  堀江貴裕、木村剛、尾野亘
- Organizer
  第65回日本心臓病学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] Serum HDL Cholesterol decreases in microRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1).2017
- Author(s)
  Takahiro Horie
- Organizer
  THE 43rd NAITO CONFERENCE Noncoding RNA :Biology, Chemistry, & Diseases
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] MicroRNA in Atherosclerosis (JCS-KSC Joint Symposium (Basic Research)2017
- Author(s)
  Takahiro Horie
- Organizer
  The 61st Annual Scientific Meeting of The Korean Society of Cardiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] LincRNA Upregulated by Pressure-Overload Induces Hypertrophy in Neonatal Mouse Cardiac Myocytes by Binding with Multiple Partners.2017
- Author(s)
  Kuwabara Y, Horie T, Baba O, Nishiga M, Nakao M, Nishino T, Nakazeki F, Koyama S, Kimura T, Ono K.
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  石川県立音楽堂外（石川県金沢市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33b promotes atherosclerotic plaque formation in Apoe-/- mice.2017
- Author(s)
  Nishino T, Horie T, Kuwabara Y, Nakao T, Nishiga M, Ide Y, Nakazeki F, Koyama S, Kimura M, Kimura T, Ono K
- Organizer
  American Heart Association Scientific Sessions 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09860
[Presentation] MicroRNA-33b promotes atherosclerotic plaque formation in Apoe-/- mice2017
- Author(s)
  Nishino T, Horie T, Baba O, Kuwabara Y, Hakuno D, Nakashima Y, Nakao T, Nishiga M, Kimura T, Ono K.
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  石川県立音楽堂外（石川県金沢市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33b promotes atherosclerotic plaque formation in Apoe-/- mice.2017
- Author(s)
  Nishino T, Horie T, Kuwabara Y, Nakao T, Nishiga M, Ide Y, Nakazeki F, Koyama S, Kimura M, Kimura T, Ono K
- Organizer
  American Heart Association Scientific Sessions 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04177
[Presentation] Changes and Physiological Meanings of Serum microRNA during Therapeutic Course of Acute Heart Failure.2016
- Author(s)
  Koyama S, Kuragaichi T, Sato Y, Kuwabara Y, Horie T, Baba O, Kimura T, Ono K.
- Organizer
  第20回　日本心不全学会学術集会
- Place of Presentation
  ロイトン札幌外（北海道札幌市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33 Maintains Cellular Cholesterol Content in Fibroblasts and Fibrotic Response in Heart2016
- Author(s)
  Masataka Nishiga, Takahiro Horie, Yasuhide Kuwabara, Osamu Baba, Tetsushi Nakao, Tomohiro Nishino, Daihiko Hakuno, Yasuhiro Nakashima, Kazuya Nagao, Koji Hasegawa, Toru Kita, Takeshi Kimura and Koh Ono.
- Organizer
  American Heart Association Annual Scientific Sessions
- Place of Presentation
  New Orleans, Louisiana（アメリカ合衆国）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33は脂質ラフト維持を介して心臓線維化を促進する2016
- Author(s)
  西賀雅隆、堀江貴裕、桑原康秀、長央和也、中尾哲史、西野共達、中関典子、井手裕也、小山智史、北徹、木村剛、尾野亘
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] LincRNAs Regulated by Pressure-overload Induce Hypertrophy in Neonatal Mouse Cardiac Myocytes2016
- Author(s)
  Yasuhide Kuwabara, Koh Ono, Takahiro Horie, Shin Watanabe, Daihiko Hakuno, Yasuhiro Nakashima, Osamu Baba, Masayasu Izuhara, Masataka Nishiga, Shunsuke Usami, Tetsushi Nakao, Tomohiro Nishino, Yuya Ide, Fumiko Nakazeki, Satoshi Koyama, Toru Kita, Takeshi Kimura
- Organizer
  第80回日本循環器学会
- Place of Presentation
  仙台
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33 Promotes Cardiac Fibrosis Through Maintaining Cellular Lpid Contents.2016
- Author(s)
  Nishiga M, Horie T, Kuwabara Y, Nakao K, Kimura T, Ono K.
- Organizer
  第20回　日本心不全学会学術集会
- Place of Presentation
  ロイトン札幌外（北海道札幌市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] マイクロRNAによるHDL代謝制御2016
- Author(s)
  堀江貴裕
- Organizer
  第48回　日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル（東京都）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] マイクロＲＮＡによるHDL代謝制御2016
- Author(s)
  堀江貴裕
- Organizer
  第48回　日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2016-07-14
- Invited
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] MicroRNA-33 Promotes Cardiac Fibrosis Through Maintaining Cellular Lpid Contents.2016
- Author(s)
  Nishiga M, Horie T, Kuwabara Y, Nakao K, Kimura T, Ono K.
- Organizer
  第20回　日本心不全学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] Expression Patterns of miRNA-423-5p in the Serum and Pericardial Fluid in Patients Undergoing Cardiac Surgery.2016
- Author(s)
  Shunsuke Usami, Shoichi Miyamoto, Yasuhide Kuwabara, Takahiro Horie, Osamu Baba, Daihiko Hakuno, Yasuhiro Nakashima, Masataka Nishiga, Masayasu Izuhara, Tetsushi Nakao, Tomohiro Nishino, Yuya Ide, Fumiko Nakazeki, Koji Ueyama, Takeshi Kimura, Koh Ono
- Organizer
  第80回日本循環器学会
- Place of Presentation
  仙台
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33bは動脈硬化形成を促進させる2016
- Author(s)
  西野　共達、堀江　貴裕、馬場　理、桑原　康秀、中尾　哲史、西賀　雅隆、宇佐美　俊輔、出原　正康、中関　典子、井手　裕也、小山　智史、尾野　亘
- Organizer
  第48回　日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル（東京都）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Changes and Physiological Meanings of Serum microRNA during Therapeutic Course of Acute Heart Failure.2016
- Author(s)
  Koyama S, Kuragaichi T, Sato Y, Kuwabara Y, Horie T, Baba O, Kimura T, Ono K.
- Organizer
  第20回　日本心不全学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] Relationship between Systemic Remodeling of Extracellular Matrix (ECM) and Clinical Course of the Disease in Heart Failure.2016
- Author(s)
  Nagao K, Yukawa H, Shimamura K, Nishiga M, Horie T, Ono K, Sato Y, Inada T, Makita T, Tanaka M.
- Organizer
  第20回　日本心不全学会学術集会
- Place of Presentation
  ロイトン札幌外（北海道札幌市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33 promotes cardiac fibrosis by maintaining cellular lipid homeostasis.2016
- Author(s)
  Masataka Nishiga, Takahiro Horie, Yasuhide Kuwabara, Osamu Baba, Tetsushi Nakao, Tomohiro Nishino, Daihiko Hakuno, Yasuhiro Nakashima, Noriko Nakazeki, Yuya Ide, Satoshi Koyama, Koji Hasegawa, Toru Kita, Takeshi Kimura, Koh Ono.
- Organizer
  BCVS 2016 Scientific Sessions
- Place of Presentation
  Phoenix, AZ（アメリカ合衆国）
- Year and Date
  2016-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] miR-33ノックアウトマウスにおける大動脈瘤についての検討2016
- Author(s)
  中尾哲史, 堀江貴裕, 馬場理, 西賀雅隆, 西野共達, 宇佐美俊輔, 桑原康秀, 出原正康, 中関典子, 井手裕也, 小山智史, 曽和尚也, 大野聡子, 青木浩樹, 尾野亘
- Organizer
  第二回J-ISCP学術集会
- Place of Presentation
  阿波観光ホテル（徳島県徳島市）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Reverse Cholesterol Transport regulated by micro RNA-332016
- Author(s)
  花田律子、西野共達、堀江貴裕、桑原康秀、西仁勇、中尾哲史、西賀雅隆、中関典子、井手裕也、小山智史、木村昌弘、Randolph Ruiz Rodriguez、曽和尚也、木村剛、尾野亘
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Overexpression of the LincRNA Regulated by Pressure-Overload Leads to Cardiomyocyte Hypertrophy.2016
- Author(s)
  Kuwabara Y, Horie T, Baba O, Nishiga M, Nakao M, Nishino T, Nakazeki F, Koyama S, Kimura T, Ono K.
- Organizer
  第20回　日本心不全学会学術集会
- Place of Presentation
  ロイトン札幌外（北海道札幌市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33は脂質ラフトの維持を介して代償性の心臓線維化を促進する2016
- Author(s)
  西賀雅隆、堀江貴裕、桑原康秀、長央和也、中尾哲史、西野共達、長谷川浩二、北徹、木村剛、尾野亘
- Organizer
  第20回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  東京コンベンションホール（東京都）
- Year and Date
  2016-12-16
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Overexpression of the LincRNA Regulated by Pressure-Overload Leads to Cardiomyocyte Hypertrophy.2016
- Author(s)
  Kuwabara Y, Horie T, Baba O, Nishiga M, Nakao M, Nishino T, Nakazeki F, Koyama S, Kimura T, Ono K.
- Organizer
  第20回　日本心不全学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] MicroRNA-33の抑制は複数の分子メカニズムを介して炎症を抑制し、大動脈瘤形成を抑制する2016
- Author(s)
  中尾哲史, 堀江貴裕, 馬場理, 西賀雅隆, 西野共達, 宇佐美俊輔, 桑原康秀, 出原正康, 中関典子, 井手裕也, 小山智史, 曽和尚也, 西仁勇, 大野聡子, 青木浩樹, 木村剛, 尾野亘
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33は細胞内コレステロール維持を通して心臓線維化を促進する2016
- Author(s)
  西賀雅隆、堀江貴裕、桑原康秀、馬場理、伯野大彦、中島康弘、中尾哲史、西野共達、長谷川浩二、北徹、木村剛、尾野亘.
- Organizer
  第二回J-ISCP学術集会
- Place of Presentation
  阿波観光ホテル（徳島県徳島市）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] High-density Lipoprotein Cholesterol Levels and Cardiovascular Outcomes in Japanese Patients after Percutaneous Coronary Intervention from the CREDO-Kyoto Registry Cohort-22016
- Author(s)
  Masayasu Izuhara, Koh Ono, Hiroki Shiomi, Takeshi Morimoto, Yutaka Furukawa, Yoshihisa Nakagawa, Satoshi Shizuta, Tomohisa Tada, Junichi Tazaki, Takahiro Horie, Yasuhide Kuwabara, Osamu Baba, Tomohiro Nishino, Toru Kita, Takeshi Kimura
- Organizer
  第80回日本循環器学会
- Place of Presentation
  仙台
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Genetic Ablation of miR-33 Attenuates Inflammation and Reduces Abdominal Aortic Aneurysm Formation2016
- Author(s)
  Tetsushi Nakao, Takahiro Horie, Osamu Baba, Masataka Nishiga, Tomohiro Nishino, Hitoo Nishi, Masayasu Izuhara, Shunsuke Usami, Noriko Nakaseki, Satoshi Koyama, Yuya Ide, Takeshi Kimura, Koh Ono
- Organizer
  American Heart Association Annual Scientific Sessions
- Place of Presentation
  New Orleans, Louisiana（アメリカ合衆国）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] マイクロRNA-33は細胞内の脂質恒常性を維持することで心臓線維化を促進する2016
- Author(s)
  西賀雅隆、堀江貴裕、桑原康秀、馬場理、伯野大彦、中島康弘、中尾哲史、西野共達、長谷川浩二、北徹、木村剛、尾野亘.
- Organizer
  第53回日本臨床分子医学会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] マイクロRNA-33を介した新たな脂質代謝制御機構の解明2016
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、木村剛、尾野亘
- Organizer
  第45回日本心脈管作動物質学会
- Place of Presentation
  徳島
- Year and Date
  2016-02-05
- Invited
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] Serum HDL cholesterol decreases in microRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor1 (Srebf1)2015
- Author(s)
  Horie T, Nishino T, Baba O, Kuwabara Y, Nakao T, Nishiga M, Usami S, Izuhara M, Nakazeki F, Ide Y, Koyama S, Sowa N, Nakashima Y, Hakuno D, Kimura T, Ono K
- Organizer
  American Heart Association Annual Scientific Sessions 2015
- Place of Presentation
  Orlando, Florida
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] SREBP-2,-1のイントロン性microRNA-33,-33bの脂質代謝における制御機構の包括的解明2015
- Author(s)
  堀江貴裕
- Organizer
  第11回榊原記念研究助成　研究成果発表会
- Place of Presentation
  東京
- Year and Date
  2015-04-18
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] マウス大動脈縮窄モデルにより増加するlincRNAはマウス心筋細胞において心肥大を誘導する2015
- Author(s)
  桑原康秀、堀江貴裕、馬場理、出原正康、宇佐美俊輔、西賀雅隆、西野共達、北徹、木村剛、尾野亘
- Organizer
  第19回　日本心不全学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-451 Aggravates Lipotoxic Cardiomyopathy through Suppression of the LKB1/AMPK Pathway.2015
- Author(s)
  Yasuhide Kuwabara, Takahiro Horie, Osamu Baba, Toru Kita, Takeshi Kimura, Koh Ono
- Organizer
  Basic Cardiovascular Sciences 2015
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2015-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-451 is Involved in Diabetic Cardiomyopathy through LKB1/AMPK Pathway2015
- Author(s)
  Kuwabara Y, Ono K, Horie T, Baba O, Nishiga M, Usami S, Izuhara M, Nakao T, Nishino T, Ide Y, Nakazeki F, Koyama S, Kita T, Kimura T
- Organizer
  第79回日本循環器学会
- Place of Presentation
  大阪国際会議場　大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Srebp1のイントロンに存在するmicroRNA-33bはHDLコレステロールを減少させる2015
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、中尾哲史、西賀雅隆、宇佐美俊輔、出原正康、中関典子、井手裕也、小山智史、曽和尚也、矢作直也、島野仁、横出正之、北徹、木村剛、尾野亘
- Organizer
  第１回国際心血管薬物療法学会日本部会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] High-density lipoprotein cholesterol levels and cardiovascular outcomes in Japanese patients after percutaneous coronary intervention: A report from the CREDO-Kyoto registry cohort-2.2015
- Author(s)
  Izuhara M, Ono K, Shiomi H, Morimoto T, Furukawa Y, Nakagawa Y, Shizuta S, Tada T, Tazaki J, Horie T, Kuwabara Y, Baba O, Nishino T, Kita T, Kimura T; CREDO-Kyoto PCI/CABG Registry Cohort-2Investigators.
- Organizer
  American Heart Association Annual Scientific Sessions 2015
- Place of Presentation
  Orlando, Florida
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Srebf1のイントロンにmicroRNA-33bをノックインしたマウスはHDLコレステロールの減少を示す2015
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、中尾哲史、西賀雅隆、宇佐美俊輔、出原正康、中関典子、井手裕也、小山智史、曽和尚也、矢作直也、島野仁、横出正之、北徹、木村剛、尾野亘
- Organizer
  第47回日本動脈硬化学会総会・学術集会
- Place of Presentation
  仙台
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] Srebp1のイントロンに存在するmicroRNA-33bはHDLコレステロールを減少させる2015
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、中尾哲史、西賀雅隆、宇佐美俊輔、出原正康、中関典子、井手裕也、小山智史、曽和尚也、矢作直也、島野仁、横出正之、北徹、木村剛、尾野亘
- Organizer
  第23回日本血管生物医学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] microRNA-451はLKB1-AMPK経路を抑制することで、ラット心筋細胞において細胞障害を、生体においては高脂肪食誘導性心肥大を誘導する2015
- Author(s)
  桑原康秀、堀江貴裕、馬場理、出原正康、宇佐美俊輔、中尾哲史、西賀雅隆、西野共達、北徹、木村剛、尾野亘
- Organizer
  第52回日本臨床分子医学会学術集会
- Place of Presentation
  みやこめっせ　京都
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] 脂質代謝を起点としたmicroRNA-33a/bの作用の解明2015
- Author(s)
  尾野　亘、堀江貴裕、桑原康秀、馬場　理、西野共達、中尾哲史、西賀雅隆、木村　剛
- Organizer
  生命素子による転写環境とエネルギー代謝のクロストーク制御｢転写代謝システム｣　平成27年度　領域班会議
- Place of Presentation
  熊本
- Year and Date
  2015-06-14
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Serum HDL-C decreases in microRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1).2015
- Author(s)
  Takahiro Horie, Tomohiro Nishino, Yasuhide Kuwabara, Osamu Baba, Takeshi Kimura, Koh Ono
- Organizer
  Basic Cardiovascular Sciences Scientific Sessions 2015
- Place of Presentation
  New Orleans, LA
- Year and Date
  2015-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] Serum HDL Cholesterol decreases in microRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1).2015
- Author(s)
  Takahiro Horie, Tomohiro Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Fumiko Nakazeki, Yuya Ide, Satoshi Koyama, Naoya Sowa, Yasuhiro Nakashima, Daihiko Hakuno, Takeshi Kimura, Koh Ono
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  Orlando, FL
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] MicroRNA-33 Encoded by an Intron of Sterol Regulatory Element-Binding Protein 2 (Srebp2) Regulates Srebp1 in vivo. Yasuhide Kuwabara,MicroRNA-451 Exacerbates Lipotoxicity in Neonatal Rat Cardiomyocytes, and High Fat Diet Induced Cardiac Hypertrophy in Mice through LKB1/AMPK Pathway.2014
- Author(s)
  Takahiro Horie, Tomohiro Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Naoya Sowa, Naoya Yahagi, Hitoshi Shimano, Masayuki Yokode, Toru Kita, Takeshi Kimura, Koh Ono,Takahiro Horie, Osamu Baba, Shin Watanabe, Masayasu Izuhara, Tetsushi Nakao, Shunsuke Usami, Tomohiro Nishino, Masataka Nishiga, Toru Kita, Takeshi Kimura, Koh Ono
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] SREBP-2のイントロンに存在するマイクロRNA-33はSREBP-1の発現を制御する2014
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、中尾哲史、西賀雅隆、宇佐美俊輔、出原正康、矢作直也、島野仁、横出正之、北徹、木村剛、尾野亘
- Organizer
  転写研究会・転写サイクル・転写代謝システム共催『若手ワークショップ2014』
- Place of Presentation
  群馬（磯部）
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] 2) MicroRNA-33 Encoded by an Intron of Sterol Regulatory Element-Binding Protein 2 (Srebp2) Regulates Srebp1 in vivo.2014
- Author(s)
  Takahiro Horie, Tomohiro Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Naoya Sowa, Naoya Yahagi, Hitoshi Shimano, Masayuki Yokode, Toru Kita, Takeshi Kimura, Koh Ono
- Organizer
  第78回　日本循環器学会学術集会
- Place of Presentation
  東京（東京国際フォーラム）
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] Shock Reduction Strategies in High Energy Devices.2014
- Author(s)
  Satoshi Shizuta, Takahiro Doi , Mitsuhiko Yahata , Tetsuma Kawaji , Kentaro Nakai , Hiroaki Sugiyama , Koji Goto , Takeru Makiyama , Koh Ono , Tetsuo Shioi , Takeshi Kimura
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein-2 (Srebp2) regulates Srebp1 in vivo2014
- Author(s)
  Horie T, Nishino T, Baba O, Kuwabara Y, Nakao T, Nishiga M, Usami S, Izuhara M, Sowa N, Yahagi N, Shimano H, Hasegawa K, Kume N Yokode M, Kita T, Kimura T, Ono K.
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  Kyoto
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] SREBP-2のイントロンに存在するマイクロRNA-33はSREBP-1の発現を制御する2014
- Author(s)
  堀江貴裕
- Organizer
  第51回日本臨床分子医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33 Encoded by an Intron of Sterol Regulatory Element-Binding Protein 2 (Srebp2) Regulates Srebp1 in vivo.2014
- Author(s)
  Takahiro Horie, Tomohiro Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Naoya Sowa, Naoya Yahagi, Hitoshi Shimano, Masayuki Yokode, Toru Kita, Takeshi Kimura, Koh Ono
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] MicroRNA-33 deficiency reduces atherosclerotic plaque progression in apoE knockout mice.2014
- Author(s)
  Baba O, Horie T, Kuwabara Y, Chujo Y, Watanabe S, Kinoshita M, Horiguchi M, Nakamura T, Chonabayashi K, Hishizawa M, Hasegawa K, Kume N Yokode M, Kita T, Kimura T, Ono K.
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  Kyoto
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-451 Exacerbates Lipotoxicity in Neonatal Rat Cardiomyocytes, and High Fat Diet Induced Cardiac Hypertrophy in Mice through LKB1/AMPK Pathway2014
- Author(s)
  Yasuhide Kuwabara,Takahiro Horie, Osamu Baba, Shin Watanabe, Masayasu Izuhara, Tetsushi Nakao, Shunsuke Usami, Tomohiro Nishino, Masataka Nishiga, Toru Kita, Takeshi Kimura, Koh Ono
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein-2 (Srebp2) regulates Srebp1 in vivo2014
- Author(s)
  Horie T, Nishino T, Baba O, Kuwabara Y, Nakao T, Nishiga M, Usami S, Izuhara M, Sowa N, Yahagi N, Shimano H, Hasegawa K, Kume N Yokode M, Kita T, Kimura T, Ono K
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  Kyoto
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] SREBP-2のイントロンに存在するマイクロRNA-33はSREBP-1の発現を制御する,microRNA-451 はLKBA-AMPK 経路を抑制することで、ラット心筋細胞において細胞障害を生体においては高脂肪食による心肥大を誘導する2014
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、中尾哲史、西賀雅隆、宇佐美俊輔、出原正康、矢作直也、島野仁、横出正之、北徹、木村剛、尾野亘,桑原康秀、堀江貴裕、馬場理、出原正康、宇佐美俊輔、中尾哲史、西賀雅隆、西野共達、井出裕也、中関典子、木村剛、尾野亘
- Organizer
  転写研究会・転写サイクル・転写代謝システム共催『若手ワークショップ2014』
- Place of Presentation
  群馬県磯部温泉
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] マイクロRNA-33欠損はアポE欠損マウスにおいて動脈硬化形成を抑制する2013
- Author(s)
  堀江貴裕、馬場理、桑原康秀、久米典昭、横出正之、北徹、木村剛、尾野亘
- Organizer
  第50回日本臨床分子医学会学術集会
- Year and Date
  2013-04-12
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE-/- Mice2013
- Author(s)
  堀江貴裕、馬場理、木村剛、尾野亘
- Organizer
  第45回日本動脈硬化学会
- Place of Presentation
  京王プラザホテルイブニングセミナー2
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] マイクロRNA制御による新規動脈硬化治療法の探索的研究2013
- Author(s)
  堀江貴裕、馬場理、桑原康秀、横出正之、北徹、木村剛、尾野亘
- Organizer
  第八回高血圧と冠動脈疾患研究会
- Place of Presentation
  大手町産経プラザ4階『サンケイホール』
- Year and Date
  2013-12-21
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 encoded by an intron of Srebf2 regulates SREBP-1 in vivo.2013
- Author(s)
  Takahiro Horie, Tomohiro Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Naoya Yahagi, Hiroshi, Shimano, Masayuki Yokode, Toru Kita, Takeshi Kimura, Koh Ono
- Organizer
  平成25年度新学術領域「転写代謝システム」第5回総括班会議: 国際シンポジウム“International Symposium on Transcription and Metabolism”
- Place of Presentation
  日本、淡路（淡路夢舞台国際会議場）
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 Deficiency Reduces the Progressio of Atherosclerotic Plaque in ApoE-/- Mice2013
- Author(s)
  堀江貴裕、馬場　理、木村　剛、尾野　亘
- Organizer
  第45回　日本動脈硬化学会学術集会、イブニングセミナー2　京王プラザホテル
- Place of Presentation
  東京（京王プラザホテル）
- Invited
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] マイクロRNA-33欠損はアポE欠損マウスにおいて動脈硬化形成を抑制する2013
- Author(s)
  堀江貴裕
- Organizer
  転写研究会・転写サイクル・転写代謝システム共催『若手ワークショップ@鬼怒川』
- Place of Presentation
  栃木ホテル鬼怒川御苑
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA encoded by an intron of Srebf2 regulates SREBP-1 in vivo.2013
- Author(s)
  Takahiro Horie
- Organizer
  平成25年度新学術領域「転写代謝システム」第5回総括班会議国際シンポジウム
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2013-11-11
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 deficiency reduces atherosclerosis formation in vivo.2013
- Author(s)
  堀江貴裕
- Organizer
  成人病の病因・病態の解明に関する研究助成　第19回研究発表会（TMFC）
- Place of Presentation
  大阪（セントレジスホテル大阪）
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 deficiency reduces atherosclerosis formation in vivo.2013
- Author(s)
  Takahiro Horie, Osamu Baba, Masataka Nishiga, Koji Hasegawa, Masayuki Yokode, Takeshi Kimura, Koh Ono.
- Organizer
  18th Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy
- Place of Presentation
  イタリア、ローマ
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 deficiency reduces atherosclerosis formation in vivo.2013
- Author(s)
  堀江貴裕
- Organizer
  成人病の病因・病態の解明に関する研究助成第19回研究発表会(TMFC)
- Place of Presentation
  大阪セントレジスホテル大阪
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 Deficiency Reduces the Progression of Atherosclerotic Plaque in apoE-/- mice2013
- Author(s)
  Takahiro Horie, Osamu Baba, Yasuhide Kuwabara, Yoshimasa Chujo，Shin Watanabe, Minako Kinoshita, Masahito Horiguchi, Tomoyuki Nakamura, Kazuhisa Chonabayashi, Masakatsu Hishizawa, Koji Hasegawa, Noriaki Kume, Masayuki Yokode, Toru Kita, Takeshi Kimura, Koh Ono
- Organizer
  第45回　日本動脈硬化学会学術集会
- Place of Presentation
  東京（京王プラザホテル）
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] マイクロRNA-33欠損はアポE欠損マウスにおいて動脈硬化形成を抑制する2013
- Author(s)
  堀江貴裕、馬場理、桑原康秀、久米典昭、横出正之、北徹、木村剛、尾野亘
- Organizer
  第50回日本臨床分子医学会学術集会
- Place of Presentation
  東京（東京国際フォーラム）
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 Deficiency Reduces the Progressio of Atherosclerotic Plaque in ApoE-/- Mice2013
- Author(s)
  堀江貴裕、馬場　理、木村　剛、尾野　亘
- Organizer
  第45回日本動脈硬化学会　イブニングセミナー2
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] MicroRNA-33 Deficiency Reduced Atherosclerosis Formation In Vivo.2012
- Author(s)
  Horie T, Baba O, Ono K, Kuwabara Y, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T
- Organizer
  ATVB Early Career Networking Reception
- Place of Presentation
  Westin Bonaventure Hotel & Suites, Los Angeles, CA
- Year and Date
  2012-11-06
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] 動脈硬化形成過程におけるマイクロRNAの機能解析～新規動脈硬化治療法の開発を目指して～2012
- Author(s)
  堀江貴裕
- Organizer
  第1回万有医学奨励賞報告会
- Place of Presentation
  東京品川ラフォーレ
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] マイクロRNA-33欠損は動脈硬化形成を抑制する2012
- Author(s)
  堀江貴裕、馬場理、尾野亘、渡邉真、木下美菜子、桑原康秀、中條克真、横出正之、北徹、木村剛
- Organizer
  第49回日本臨床分子医学会学術集会
- Place of Presentation
  京都みやこメッセ
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] マイクロRNA-33欠損は動脈硬化形成を抑制する2012
- Author(s)
  堀江貴裕、馬場理、尾野亘、桑原康秀、曽和尚也、長谷川浩二、久米典昭、横出正之、北徹、木村剛
- Organizer
  平成24年度『転写代謝システム領域班会議
- Place of Presentation
  筑波グランドホテル
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] マイクロRNA-33は動脈硬化形成を制御する2012
- Author(s)
  堀江貴裕、馬場理、尾野亘、渡邉真、西仁勇、木下美菜子、桑原康秀、中條克真、横出正之、木村剛
- Organizer
  第109回日本内科学会講演会
- Place of Presentation
  京都みやこメッセ
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] Increased MicroRNA-1 and Micro RNA-133a Levels in Serum of Patients with Cardiovascular Disease Indicate the Existence of Myocardial Damage2012
- Author(s)
  Koh Ono, Yasuhide Kuwabara, Takahiro Horie, Toru Kita, Takeshi Kimura
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-33 deficiency reduces atherosclerosis formation in vivo.2012
- Author(s)
  Takahiro Horie, Osamu Baba, Koh Ono, Yasuhide Kuwabara, Naoya Sowa, Koji Hasegawa, Noriaki Kume, Masayuki Yokode, Toru Kita, Takeshi Kimura
- Organizer
  第20回日本血管生物医学会学術集会
- Place of Presentation
  徳島あわぎんホール
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 Regulates Atherosclerosis Formation2012
- Author(s)
  Takahiro Horie, Osamu Baba, Koh Ono, Shin Watanabe, Hitoo Nishi, Minako Kinoshita, Yasuhide Kuwabara, Yoshimasa Chujo, Naoya Sowa, Koji Hasegawa, Noriaki Kum, Masayuki Yokode, Toru Kita, Takeshi Kimura
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA 26b Encoded by the Intron of SCP1 Has an Antagonistic on its Host Gene and Cardiac Hypertrophy2012
- Author(s)
  Naoya Sowa, Koh Ono, Takahiro Horie, Koji Hasegawa, Toru Kita, Takeshi Kimura
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA 33 Deficiency Reduces Atherosclerotic Plaque progression in ApoE Knockout Mice2012
- Author(s)
  Baba O, Horie T, Nakamura T, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T, and Ono K
- Organizer
  European Society of Cardiology Congress 2012
- Place of Presentation
  Munich - Germany
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] MicroRNA-33 deficiency reduced atherosclerosis formation in vivo.2012
- Author(s)
  Takahiro Horie, Osamu Baba, Koh Ono, Shin Watanabe, Hitoo Nishi, Minako Kinoshita, Yasuhide Kuwabara, Yoshimasa Chujo, Naoya Sowa, Koji Hasegawa, Noriaki Kume, Masayuki Yokode, Toru Kita, Takeshi Kimura
- Organizer
  第44回日本動脈硬化学会学術集会
- Place of Presentation
  博多
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] Circulating MicroRNAs Drived from Damaged Cardiomyocytes can Regulate the Gene Expression in Recipient CellsicroRNA-33 Regulates Atherosclerosis Formation2012
- Author(s)
  Yasuhide Kuwabara, Koh Ono, Takahiro Horie, Hitoo Nishi, Shin Watanabe, Minako Kinoshita, Osamu Baba, Yoshimasa Chujo, Toru Kita, Takeshi Kimura
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-33 Deficiency Reduced Atherosclerosis Formation In Vivo.2012
- Author(s)
  Horie-T
- Organizer
  American Heart Association Annual Scientific Sessions 2012
- Place of Presentation
  Los Angels Convention Center, LA, USA
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] MicroRNA-33 regulates atherosclerosis formation.2012
- Author(s)
  Horie-T
- Organizer
  Japanese Circulation Society
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] MicroRNA-33 deficiency reduced atherosclerosis formation in vivo.2012
- Author(s)
  Takahiro Horie, Osamu Baba, Koh Ono, Yasuhide Kuwabara, Naoya Sowa, Koji Hasegawa, Noriaki Kume, Masayuki Yokode, Toru Kita, Takeshi Kimura
- Organizer
  第3回 Molecular Cardiovascular ConferenceII
- Place of Presentation
  北海道キロロ
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 Deficiency Reduced Atherosclerosis Formation In Vivo.,MicroRNA 33 Deficiency in Leukocytes Reduced the Lipid Accumulation in Atherosclerotic Plaque in ApoE Knockout Mice.2012
- Author(s)
  Horie T, Baba O, Ono K, Kuwabara Y, Hasegawa K, Kume N, Yokode M, Kita T, and Kimura T,Baba O, Horie T, Kuwabara Y, Izuhara M, Usami S, Nakao T, Nishiga M, Nishino T, Sowa N, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T, and Ono K
- Organizer
  American Heart Association Annual Scientific Sessions 2012
- Place of Presentation
  Los Angeles Convention Center
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 Regulates Atherosclerosis Formation2012
- Author(s)
  Takahiro Horie, Osamu Baba, Koh Ono, Shin Watanabe, Hitoo Nishi, Minako Kinoshita, Yasuhide Kuwabara, Yoshimasa Chujo, Naoya Sowa, Koji Hasegawa, Noriaki Kume, Masayuki Yokode, Toru Kita, Takeshi Kimura
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA 33 Deficiency Reduces Atherosclerotic Plaque progression in ApoE Knockout Mice.2012
- Author(s)
  Baba O, Horie T, Nakamura T, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T, and Ono K
- Organizer
  European Society of Cardiology Congress 2012
- Place of Presentation
  Germany
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA 26b Encoded by the Intron of SCP1 Has an Antagonistic on its Host Gene and Cardiac Hypertrophy2012
- Author(s)
  Naoya Sowa, Koh Ono, Takahiro Horie, Koji Hasegawa, Toru Kita, Takeshi Kimur
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] マイクロRNA-33欠損は動脈硬化形成を抑制する2012
- Author(s)
  堀江貴裕
- Organizer
  第49回日本臨床分子医学会学術集会
- Place of Presentation
  京都みやこメッセ
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 Deficiency Reduced Atherosclerosis Formation In Vivo2012
- Author(s)
  Horie T, Baba O, Ono K, Kuwabara Y, Hasegawa K, Kume N, Yokode M, Kita T, and Kimura T
- Organizer
  American Heart Association Annual Scientific Sessions 2012
- Place of Presentation
  Los Angeles Convention Center
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] MicroRNA-33 deficiency reduced atherosclerosis formation in vivo.2012
- Author(s)
  . Horie, O. Baba, K. Ono, S. Watanabe, H. Nishi, M. Kinoshita, Y. Kuwabara, Y. Chujo, N. Sowa, K. Hasegawa, N. Kume, M. Yokode, T. Kita, T. Kimura
- Organizer
  第44回日本動脈硬化学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] MicroRNA-33 deficiency reduces atherosclerosis formation in vivo.2012
- Author(s)
  Takahiro Horie, Osamu Baba, Koh Ono, Yasuhide Kuwabara, Naoya Sowa, Koji Hasegawa, Noriaki Kume, Masayuki Yokode, Toru Kita, Takeshi Kimura
- Organizer
  第20回日本血管生物医学会学術集会[併催] 第10回Korea-Japan Joint Symposium on Vascular Biology
- Place of Presentation
  徳島あわぎんホール
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] Circulatin Micro RNAs Drived from Damaged Cardiomyocytes can Regulate the Gene Expression in Recipient CellsicroRNA-33 Regulates Atherosclerosis Formation2012
- Author(s)
  Yasuhide Kuwabara, Koh Ono, Takahiro Horie, Hitoo Nishi, Shin Watanabe, Minako Kinoshita, Osamu Baba, Yoshimasa Chujo, Toru Kita, Takeshi Kimura
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-33 Deficiency Reduced Atherosclerosis Formation In Vivo.2012
- Author(s)
  Horie T, Baba O, Ono K, Kuwabara Y, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T
- Organizer
  American Heart Association Annual Scientific Sessions 2012
- Place of Presentation
  Los Angeles, California.
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients with Cardiovascular Disease Indicate the Existence of Myocardial Damage2012
- Author(s)
  Koh Ono, Yasuhide Kuwabara, Takahiro Horie, Toru Kita, Takeshi Kimura
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] マイクロRNA-33は動脈硬化形成を制御する2012
- Author(s)
  堀江貴裕、馬場理、尾野亘、渡邉真、西仁勇、木下美菜子、桑原康秀、中條克真、横出正之、木村剛
- Organizer
  第109回日本内科学会講演会
- Place of Presentation
  京都みやこメッセ
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] CaMKK beta contributes to energy supply in adaptive phase of pressure-overload-induced heart failure2011
- Author(s)
  S. Watanabe, K. Ono, T. Horie, H. Nishi, Y. Kuwabara, O. Baba, T. Kimura
- Organizer
  ESC Congress 2011
- Place of Presentation
  Paris Nord Villepinte(Paris, France)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] Elevated microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular diseases indicate the myocardial damage2011
- Author(s)
  Y. Kuwabara, K. Ono, T. Horie, H. Nishi, S. Watanabe, M. Kinoshita, O. Baba, T. Kita, T. Kimura
- Organizer
  ESC Congress 2011
- Place of Presentation
  Paris Nord Villepinte(Paris, France)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients with Cardiovascular Disease Indicate the Existence of Myocardial Damage2011
- Author(s)
  Yasuhide Kuwabara, Koh Ono, Takahiro Horie, Hitoo Nishi, Shin Watanabe, Minako Kinoshita, Osamu Baba, Yoshimsa Chuio, Kazuya Nagao, Yoii Kojima, Toru Kita, Takeshi Kimura
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orlando (America)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA 26b Encoded by the Intron of Small CTD Phosphatases(SCPs) Has an Antagonistic Effect on its Host Gene and Suppresses Cardiac Hypertrophy2011
- Author(s)
  Naoya Sowa, Koh Ono, Takahiro Horie, Koji Hasegawa, Takeshi Kimura
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orange County Convention Center(Orlando, USA)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA 26b Encoded by the Intron of Small CTD Phosphatases (SCPs) Hasan Antagonistic Effect on its Host Gene and Suppresses Cardiac Hypertrophy2011
- Author(s)
  Naoya Sowa, Koh Ono, Takahiro Horie, Koji Hasegawa, Takeshi Kimura
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orlando (America)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] Elevated microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular diseases indicate the myocardial damage2011
- Author(s)
  Y.Kuwabara, K.Ono, T.Horie, H.Nishi, S.Watanabe, M.Kinoshita, O.Baba, T.Kita, T.Kimura
- Organizer
  ESC Congress 2011
- Place of Presentation
  Paris (France)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-1 and microRNA-133a elevations in serum of patients with cardiovascular disease indicate the existence of myocardial damage2011
- Author(s)
  Kuwabara Y, Ono K, Horie T, Nishi H, Watanabe S, Kinoshita M, Baba O, Chujo Y, Nagao K, Kojima Y, Kita T, Kimura T
- Organizer
  American Heart Association Annual Scientific Sessions
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] CaMKK beta contributes to energy supply in adaptive phase of pressure-overload-induced heart failure2011
- Author(s)
  S.Watanabe, K.Ono, T.Horie, H.Nishi, Y.Kuwabara, O.Baba, T.Kimura
- Organizer
  ESC Congress 2011
- Place of Presentation
  Paris (France)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients with Cardiovascular Disease Indicate the Existence of Myocardial Damage2011
- Author(s)
  Yasuhide Kuwabara, Koh Ono, Takahiro Horie, Hitoo Nishi, Shin Watanabe, Minako Kinoshita, Osamu Baba, Yoshimasa Chujo, Kazuya Nagao, Yoji Kojima, Toru Kita, Takeshi Kimura
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orange County Convention Center(Orlando, USA)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] Neural cell adhesion molecule is a cardioprotective factor upregulated by metabolic stress2011
- Author(s)
  Nagao K, Ono K, Horie T, Tamaki Y, Iwanaga Y, Makita T, Inada T, Tanaka M, Kita T, Kimura T
- Organizer
  European Society of Cardiology Congress
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-23390211
[Presentation] ドキソルビシンによる心筋障害にはmiR-146aによるneuregulin/ErbBシグナルの抑制が関わる2010
- Author(s)
  堀江貴裕、尾野亘、西仁勇、長央和也、木下美菜子、桑原康秀、森利依子、長谷川浩二、北徹、木村剛
- Organizer
  第47回日本臨床分子医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MiR-146a-induced inhibition of the neuregulin-ErbB4 pathway may be involved in deterioration of cardiotoxicity under concurrent chemotherapy with doxorubicin and Trastuzumab2010
- Author(s)
  Horie T, Ono K, Iwanaga Y, Nishi H, Nagao K, Kinoshita M, Watanabe S, Kuwabara Y, Nakashima Y, Takanabe-Mori R, Nishi E, Hasegawa K, Kita T, Kimura T
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  McCormick Place(Chicago, USA)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-448は脂肪細胞分化を抑制する2010
- Author(s)
  木下美菜子、尾野亘、桑原康秀、西仁勇、長央和也、堀江貴裕、森利依子、長谷川浩二、北徹、木村剛
- Organizer
  第47回日本臨床分子医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] SREBP2のイントロンにコードされるマイクロRNA-33は生体においてHDLの形成を制御する2010
- Author(s)
  堀江貴裕、尾野亘、西仁勇、長央和也、木下美菜子、桑原康秀、森利依子、長谷川浩二、北徹、木村剛
- Organizer
  第2回京阪神心不全研究会
- Place of Presentation
  阪急電鉄本社ビル1階(大阪)
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-1 and microRNA-133a are useful as early diagnostic biomarkers in patients with acute coronary syndrome2010
- Author(s)
  Kuwabara Y, Ono K, Horie T, Nishi H, Kinoshita M, Watanabe S, Nakashima Y, Nagao K, Kojima Y, Kita T, Kimura T.
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  McCormick Place(Chicago, USA)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-1 and microRNA-133a are useful as early diagnostic biomarkers in patients with acute coronary syndrome.2010
- Author(s)
  Kuwabara Y, Ono K, Horie T, Nishi H, Kinoshita M, Watanabe S, Nakashima Y, Nagao K, Kojima Y, Kita T, Kimura T
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via Arl2 in neonatal rat cardiac myocytes2010
- Author(s)
  Ono K, Nishi H, Iwanaga Y, Horie T, Nagao K, Takemura G, Kinoshita M, Kuwabara Y, Takanabe-Mori R, Hasegawa K, Kita T, Kimura T.
- Organizer
  ISHR World Congress 2010 Kyoto
- Place of Presentation
  京都国際会議場(京都)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MiR-146a-induced inhibition of the neuregulin-ErbB4 pathway may be involved in deterioration of cardiotoxicity under concurrent chemotherapy with doxorubicin and Trastuzumab.2010
- Author(s)
  Horie T, Ono K, Iwanaga Y, Nishi H, Nagao K, Kinoshita M, Watanabe S, Kuwabara Y, Nakashima Y, Takanabe-Mori R, Nishi E, Hasegawa K, Kita T, Kimura T
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA 26b family encoded by the introns of small CTD Phosphatases(SCPs) 1 to 3 suppresses phenylephrine-induced cardiomyocyte hypertrophy by targeting TRPC3/6 and GATA42010
- Author(s)
  Ono K, Sowa N, Horie T, Hasegawa K, Kita T, Kimura T.
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  McCormickPlace(Chicago, USA)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-27a regulates beta-myocin heavy chain gene expression by targeting thyroid hormone receptor beta 1 in neonatal rat ventricular myocytes2010
- Author(s)
  Nishi H, Ono K, Horie T, Nagao K, Kinoshita M, Kuwabara Y, Baba O, Nakashima Y, Nagao K, Takanabe-Mori R, Hasegawa K, Kita T, Kimura T.
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  McCormick Place(Chicago, USA)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] Ca2+/Calumodulin-dependent kinase kinase beta contributes to energy supply in adaptive phase of pressure-overload-induced heart failure.2010
- Author(s)
  Watanabe S, Ono K, Horie T, Nishi H, Kinoshita M, Kuwabara Y, Baba O, Kimura T
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via Ar12 in neonatal rat cardiac myocytes.2010
- Author(s)
  Ono K, Nishi H, Iwanaga Y, Horie T, Nagao K, Takemura G, Kinoshita M, Kuwabara Y, Takanabe-Mori R, Hasegawa K, Kita T, Kimura T
- Organizer
  ISHR World Congress 2010 Kyoto
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] Ca2+/calmodulin-dependent kinase kinase beta contributes to energy supply in adaptive phase of pressure-overload-induced heart failure2010
- Author(s)
  Watanabe S, Ono K, Horie T, Nishi H, Kuwabara Y, Kimura T.
- Organizer
  European Society of Cardiology Congress 2010
- Place of Presentation
  Stockholmsmassan(Stockholm, Sweden)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] SREBP2のイントロンにコードされるマイクロRNA-33は生体においてHDLの形成を制御する2010
- Author(s)
  堀江貴裕、尾野亘、西仁勇、長央和也、木下美菜子、桑原康秀、森利依子、長谷川浩二、北徹、木村剛
- Organizer
  第2回京阪神心不全研究会
- Place of Presentation
  大阪
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA 26b family encoded by the introns of small CTD Phosphatases (SCPs) 1 to 3 suppresses phenylephrine-induced cardiomyocyte hypertrophy by targeting TRPC3/6 and GATA42010
- Author(s)
  Ono K, Sowa N, Horie T, Hasegawa K, Kita T, Kimura T
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] ドキソルビシンによる心筋障害にはmiR-146aによるneuregulin/ErbBシグナルの抑制が関わる2010
- Author(s)
  堀江貴裕、尾野亘、西仁勇、長央和也、木下美菜子、桑原康秀、森利依子、長谷川浩二、北徹、木村剛
- Organizer
  第47回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-448は脂肪細胞分化を抑制する2010
- Author(s)
  木下美菜子、尾野亘、桑原康秀、西仁勇、長央和也、堀江貴裕、森利依子、長谷川浩二、北徹、木村剛
- Organizer
  第47回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] Ca2+/Calumodulin-dependent kinase kinase beta contributes to energy supply in adaptive phase of pressure-overload-induced heart failure2010
- Author(s)
  Watanabe S, Ono K, Horie T, Nishi H, Kinoshita M, Kuwabara Y, Baba O, Kimura T.
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  McCormick Place(Chicago, USA)
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-27a regulates beta-myocin heavy chain gene expression by targeting thyroid hormone receptor beta 1 in neonatal rat ventricular my ocytes.2010
- Author(s)
  Nishi H, Ono K, Horie T, Nagao K, Kinoshita M, Kuwabara Y, Baba O, Nakashima Y, Nagao K, Takanabe-Mori R, Hasegawa K, Kita T, Kimura T
- Organizer
  American Heart Association Annual Scientific Sessions 2010
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] MicroRNA-33b Knock-in Mice for an Intron of Sterol Regulatory Element-Binding Factor 1 (Srebf1) Exhibit Reduced HDL-C in vivo
- Author(s)
  Horie T, Nishino T, Baba O, Kuwabara Y, Nakao T, Nishiga M, Usami S, Izuhara M, Ide Y, Nakazeki F, Koyama S, Yokode M, Kita T, Kimura T, Ono K.
- Organizer
  American Heart Association Annual Scientific Sessions 2014
- Place of Presentation
  Chicago
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-451 is involved in diabetic cardiomyopathy through suppression of the LKB1/AMPK pathway.
- Author(s)
  Kuwabara Y, Horie T, Baba O, Nishiga M, Usami S, Izuhara M, Nakao T, Nishino T, Kita T, Kimura T, Ono K.
- Organizer
  9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  Kyoto
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] miR-33ノックアウトマウスにおける大動脈瘤についての検討
- Author(s)
  中尾哲史、堀江貴裕、馬場　理、西賀雅隆、西野共達、宇佐美俊輔、桑原康秀、出原正康、中関典子、井手裕也、小山智史、曽和尚也、大野聡子、青木浩樹、木村　剛、尾野　亘
- Organizer
  学術領域研究　転写代謝システム　新学術領域若手ワークショップ
- Place of Presentation
  伊香保
- Year and Date
  2015-02-06 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] 心肥大・心不全におけるlincRNAの機能解析
- Author(s)
  桑原康秀、堀江貴裕、中島康弘、伯野大彦、馬場　理、出原正康、宇佐美俊輔、西賀雅隆、西野共達、中尾哲史、井手裕也、中関典子、小山智史、北　徹、木村　剛、尾野　亘
- Organizer
  学術領域研究　転写代謝システム　新学術領域若手ワークショップ
- Place of Presentation
  伊香保
- Year and Date
  2015-02-06 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] SREBP-2のイントロンに存在するマイクロRNA-33はSREBP-1の発現を制御する。
- Author(s)
  堀江貴裕
- Organizer
  Research PlaNet 2014
- Place of Presentation
  東京
- Year and Date
  2014-05-10 – 2014-05-11
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] 心血管代謝疾患形成に関与するマイクロRNAの機能解析
- Author(s)
  堀江貴裕
- Organizer
  第50回高血圧モデル学会学術総会
- Place of Presentation
  和歌山
- Year and Date
  2014-12-05 – 2014-12-06
- Invited
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates Srebp1 in vivo.
- Author(s)
  Takahiro Horie, Tomohiro Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Naoya Sowa, Naoya Yahagi, Hitoshi Shimano, Koji Hasegawa, Noriaki Kume, Masayuki Yokode, Toru Kita, Takeshi Kimura, Koh Ono
- Organizer
  The 18th International Vascular Biology Meeting (IVBM)
- Place of Presentation
  Japan, Kyoto
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] MicroRNA-33 deficiency leads to high fat diet- induced obesity and insulin resistance in vivo.
- Author(s)
  Horie T, Nishino T, Baba O, Kuwabara Y, Nakano T, Nishiga M, Usami S, Izuhara M, Kimura T, Ono K.
- Organizer
  European Society of Cardiology Congress 2014
- Place of Presentation
  Barcerona
- Year and Date
  2014-08-30 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33, embedded in Srebf2 intron, regulate fatty acid synthesis through targeting SREBP-1 in vivo.
- Author(s)
  Nishino T, Horie T, Baba O, Kuwabara Y, YOkode M, Kita T, Kimura T, Ono K.
- Organizer
  European Society of Cardiology Congress 2014
- Place of Presentation
  Barcerona
- Year and Date
  2014-08-30 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33 deficiency reduces atherosclerotic plaque progression in apoE knockout mice.
- Author(s)
  Baba O, Horie T, Ono K, Kuwabara Y, Sowa N, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T.
- Organizer
  9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  Kyoto
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] マイクロRNA制御による新規動脈硬化治療法の探索的研究
- Author(s)
  堀江貴裕、馬場理、桑原康秀、横出正之、北徹、木村剛、尾野亘
- Organizer
  第八回　高血圧と冠動脈疾患研究会
- Place of Presentation
  東京（サンケイホール）
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] Srebf1のイントロンにmicroRNA-33bをノックインしたマウスはHDLコレステロールの減少を示す。
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、中尾哲史、西賀雅隆、宇佐美俊輔、出原正康、中関典子、井手裕也、小山智史、曽和尚也、矢作直也、島野仁、横出正之、北徹、木村剛、尾野亘
- Organizer
  若手ワークショップ＠伊香保（転写研究会＆転写サイクル＆転写代謝システム共催）
- Place of Presentation
  群馬
- Year and Date
  2015-02-05 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] microRNA-33b promotes atherosclerotic plaque formation in vivo
- Author(s)
  西野共達、堀江貴裕、馬場理、桑原康秀、尾野　亘
- Organizer
  学術領域研究　転写代謝システム　新学術領域若手ワークショップ
- Place of Presentation
  伊香保
- Year and Date
  2015-02-06 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33 Deficiency Reduced Atherosclerosis Formation In Vivo.
- Author(s)
  Horie T, Baba O, Ono K, Kuwabara Y, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T
- Organizer
  ATVB Early Career Networking Reception. 2012
- Place of Presentation
  Los Angeles, California.
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] マイクロRNA-33の骨髄機能および慢性炎症における役割
- Author(s)
  馬場理、堀江貴裕、伯野大彦、中島康弘、桑原康秀、中尾哲史、出原正康、宇佐美俊輔、西賀雅隆、西野共達、井手裕也、中関典子、小山智史、木村　剛、尾野　亘
- Organizer
  学術領域研究　転写代謝システム　新学術領域若手ワークショップ
- Place of Presentation
  伊香保
- Year and Date
  2015-02-06 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Srebf1のイントロンにmicroRNA-33bをノックインしたマウスはHDLコレステロールの減少を示す。
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、中尾哲史、西賀雅隆、宇佐美俊輔、出原正康、井手裕也、中関典子、小山智史、曽和尚也、木村剛、尾野亘
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] Microrna-33, Located Within Srebf2 Intron, Regulate Fatty Acid Synthesis via Targeting SREBP-1 in vivo
- Author(s)
  Nishino T, Horie T, Baba O, Kuwabara Y, Nakao T, Nishiga M, Usami S, Izuhara M, Ide Y, Nakazeki F, Koyama S, Yokode M, Kita T, Kimura T, Ono K.
- Organizer
  American Heart Association Annual Scientific Sessions 2014
- Place of Presentation
  Chicago
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33 deficiency leads to high fat diet- induced obesity and insulin resistance in vivo.
- Author(s)
  Takahiro Horie, Tomohiro Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Naoya Sowa, Takeshi Kimura, and Koh Ono
- Organizer
  European Society of Cardiology Congress 2014
- Place of Presentation
  Spain, Barcelona
- Year and Date
  2014-08-30 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] Serum HDL-C decreases in microRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor (Srebf1).
- Author(s)
  Takahiro Horie, Tomohiro, Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Takeshi Kimura, Koh Ono
- Organizer
  9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress (MSDA)
- Place of Presentation
  Japan, Kyoto
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] MicroRNA-33b Knock-in Mice for an Intron of Sterol Regulatory Element-Binding Factor 1 (Srebf1) Exhibit Reduced HDL-C in vivo.
- Author(s)
  Takahiro Horie, Tomohiro Nishino, Osamu Baba, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Fumiko Nakazeki, Yuya Ide, Satoshi Koyama, Masayuki Yokode, Takeshi Kimura, and Koh Ono
- Organizer
  American Heart Association 2014 Scientific Sessions
- Place of Presentation
  USA, Chicago
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] マイクロRNA-33による脂質代謝制御機構の解明
- Author(s)
  堀江貴裕
- Organizer
  第46回　日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-10 – 2014-07-11
- Invited
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] Ca2+/calmodulin-dependent kinase kinase beta contributes to energy supply in adaptive phase of pressure-overload-induced heart failure.
- Author(s)
  Watanabe S, Ono K, Horie T, Nishi H, Kuwabara Y, Kimura T
- Organizer
  European Society of Cardiology Congress 2010
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-22790703
[Presentation] Srebf1のイントロンにmicroRNA-33bをノックインしたマウスはHDLコレステロールの減少を示す
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、中尾哲史、西賀雅隆、宇佐美俊輔、出原正康、中関典子、井手裕也、小山智史、曽和尚也、矢作直也、島野　仁、横出正之、北　徹、木村　剛、尾野　亘
- Organizer
  学術領域研究　転写代謝システム　新学術領域若手ワークショップ
- Place of Presentation
  伊香保
- Year and Date
  2015-02-06 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] Serum HDL-C decreases in microRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1).
- Author(s)
  Horie T, Nishino T, Baba O, Kuwabara Y, Nakano T, Nishiga M, Usami S, Izuhara M, Kimura T, Ono K.
- Organizer
  9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  Kyoto
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26293186
[Presentation] MicroRNA-33 deficiency reduces atherosclerosis formation in vivo.
- Author(s)
  Takahiro Horie, Osamu Baba, Masataka Nishiga, Koji Hasegawa, Masayuki Yokode, Takeshi Kimura, Koh Ono
- Organizer
  18th Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy 28th-30th June
- Place of Presentation
  Italy, Roma
- Data Source
  KAKENHI-PROJECT-24790753
[Presentation] SREBP-2のイントロンに存在するマイクロRNA-33はSREBP-1の発現を制御する。
- Author(s)
  堀江貴裕、西野共達、馬場理、桑原康秀、矢作直也、島野仁、横出正之、北徹、木村剛、尾野亘
- Organizer
  第51回日本臨床分子医学会
- Place of Presentation
  東京
- Year and Date
  2014-04-11 – 2014-04-12
- Data Source
  KAKENHI-PROJECT-26461144
[Presentation] MicroRNA-33, embedded in Srebf2 intron, regulate fatty acid synthesis through targeting SREBP-1 in vivo.
- Author(s)
  Nishino T, Horie T, Baba O, Kuwabara Y, YOkode M, Kita T, Kimura T, Ono K. MicroRNA-33, embedded in Srebf2 intron, regulate fatty acid synthesis through targeting SREBP-1 in vivo.
- Organizer
  9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  Kyoto
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26293186

1. ONO KOH (00359275)

# of Collaborated Projects: 5 results

# of Collaborated Products: 63 results
2. NAKAMURA Tomoyuki (20362527)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. KAKEYA Hideaki (00270596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SATO Fumiaki (20467426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MARUSAWA Hiroyuki (80324630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 馬場理 (30758446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KIMURA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. MURAYAMA Toshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中島康弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 西英一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 松田哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 古川裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 西野共達

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 伯野大彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 高谷智英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 堀江稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 柳田素子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 横出正之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 河原真大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 矢作直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 井手裕也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Horie Takahiro 堀江 貴裕

HORIE Takahiro 堀江 貴裕

Research Projects

Research Products

Co-Researchers

非コードRNAによる褐色脂肪細胞・ベージュ脂肪細胞の活性化機構の解明Principal Investigator

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Elucidation of the pathophysiology of aortic aneurysms and development of novel therapeutic agents to inhibit their progression and promote their regression

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Elucidation of the functions of long non-coding RNA in cardiovascular diseases

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Functional analysis of cholesterol-related long non-coding RNAs and their clinical applicationPrincipal Investigator

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Investigation of the role of microRNAs in the formation of liver fibrosisPrincipal Investigator

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Elucidation of global metabolic control mechanisms by microRNA-33a/b and development of specific regulatory strategy using artificial nucleic acid

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Elucidation of the functions of microRNA-33 in homeostasis in vivo

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Elucidation of the regulatory mechanism of lipid metabolism by intronic microRNA-33a, -33bPrincipal Investigator

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Investigation of the novel prevention and treatment for atherosclerosis by microRNA modulationPrincipal Investigator

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Elucidation of the functions of miR-33a/b in cholesterol homeostasis

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Elucidation of the function of microRNAs on cardiovascular and metabolic disease : Investigation for a novel therapy by regulating microRNAsPrincipal Investigator

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[Book] マイクロRNA-33の動脈硬化形成における機能・役割について

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[Journal Article] MicroRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity.2021

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NAID

Horie Takahiro 堀江貴裕

HORIE Takahiro 堀江貴裕