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ODA Toshiyuki  小田 賢幸

… Alternative Names

Oda Toshiyuki  小田 賢幸

ODA TOSHIYUKI  小田 賢幸

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Researcher Number 20569090
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-8090-2159
Affiliation (Current) 2025: 山梨大学, 大学院総合研究部, 教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 山梨大学, 大学院総合研究部, 教授
2017 – 2018: 山梨大学, 大学院総合研究部, 教授
2015 – 2016: 山梨大学, 総合研究部, 教授
2012: 東京大学, 大学院・医学系研究科, 助教
2011 – 2012: 東京大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Transformative Research Areas, Section (III) / Basic Section 48010:Anatomy-related / General anatomy (including histology/embryology) / Biological Sciences / Biophysics
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords
Principal Investigator
クライオ電子顕微鏡 / 繊毛 / 微小管 / ダイニン / 三次元構造解析 / 分子モーター / 構造生物学 / トモグラフィー / 免疫 / 表皮 … More / ウイルス / 免疫防御 / 膀胱上皮 / 電子顕微鏡 / 翻訳後修飾 / 繊毛・鞭毛 / 細胞骨格 / モータータンパク質 / 運動性繊毛 / 細胞生物学 / 鞭毛 / 三次元再構成 / 鞭毛・繊毛 / 鞭毛・線毛 … More
Except Principal Investigator
高脂肪食 / アウエルバッハ神経叢 / 3次元再構築 / SBF-SEM / 筋層間神経叢 / SGLT阻害薬 / 消化管運動障害 / 糖尿病性自律神経障害 / 糖尿病 / intraflagellar transport / ダイニン2 / 繊毛 / クラミドモナス / IFT / 繊毛内輸送 / 逆行性輸送 / ダイナクチン / ダイニン Less
  • Research Projects

    (8 results)
  • Research Products

    (42 results)
  • Co-Researchers

    (13 People)
  •  Structural and dynamic analysis of biological clusters by cryo-TEM and SEMPrincipal Investigator

    • Principal Investigator
      小田 賢幸
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      University of Yamanashi
  •  肥満・糖尿病に伴う自律神経障害の病態形成メカニズムの解明と新規治療法の開発

    • Principal Investigator
      志茂 聡
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Health Science University
  •  Cryo-electron tomography of Birbeck granulesPrincipal Investigator

    • Principal Investigator
      小田 賢幸
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      University of Yamanashi
  •  Elucidation of Molecular Sorting Mechanisms using Cryo-electron microscopyPrincipal Investigator

    • Principal Investigator
      Oda Toshiyuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      University of Yamanashi
  •  In vitro reconstitution of intraflagellar transport by cytoplasmic dynein-2

    • Principal Investigator
      Niwa Shinsuke
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Tohoku University
  •  Three-dimensional Structural Analysis of CiliaPrincipal Investigator

    • Principal Investigator
      ODA TOSHIYUKI
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      University of Yamanashi
  •  分子定規による運動性シリア構築メカニズムの解明Principal Investigator

    • Principal Investigator
      小田 賢幸
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Yamanashi
  •  Structural and Functional Analyses of Axonemal Dynein Intermediate ChainPrincipal Investigator

    • Principal Investigator
      ODA Toshiyuki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2018 2017 2016 2015 2013 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] Tubulin glycylation controls ciliary motility through modulation of outer-arm dyneins2024

    • Author(s)
      Tomohiro Kubo1, Rinka Sasaki, and Toshiyuki Oda
    • Journal Title

      Molecular Biology of the Cell

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02654
  • [Journal Article] α- and β-tubulin C-terminal tails with distinct modifications are crucial for ciliary motility and assembly2023

    • Author(s)
      Kubo Tomohiro、Tani Yuma、Yanagisawa Haru-Aki、Kikkawa Masahide、Oda Toshiyuki
    • Journal Title

      Journal of Cell Science

      Volume: 136 Issue: 16

    • DOI

      10.1242/jcs.261070

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K05829, KAKENHI-PLANNED-21H05248, KAKENHI-PROJECT-21H04762, KAKENHI-PROJECT-21H02654
  • [Journal Article] Cryo-EM elucidates the uroplakin complex structure within liquid-crystalline lipids in the porcine urothelial membrane2023

    • Author(s)
      Yanagisawa Haruaki、Kita Yoshihiro、Oda Toshiyuki、Kikkawa Masahide
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1 Pages: 1018-1018

    • DOI

      10.1038/s42003-023-05393-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21H05248, KAKENHI-PUBLICLY-22H05538, KAKENHI-PROJECT-21H04762, KAKENHI-PROJECT-21H02654
  • [Journal Article] Cryo-electron tomography of Birbeck granules reveals the molecular mechanism of langerin lattice formation2022

    • Author(s)
      T. Oda, H. Yanagisawa, H. Shinmori, Y. Ogawa, T. Kawamura
    • Journal Title

      eLife

      Volume: 11

    • DOI

      10.7554/elife.79990

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K04674, KAKENHI-PUBLICLY-22H05538, KAKENHI-PROJECT-21H02654
  • [Journal Article] Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a2021

    • Author(s)
      Hou Yuqing、Zhao Lei、Kubo Tomohiro、Cheng Xi、McNeill Nathan、Oda Toshiyuki、Witman George B.
    • Journal Title

      Journal of Cell Science

      Volume: 134 Issue: 12 Pages: 1-11

    • DOI

      10.1242/jcs.258540

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16123, KAKENHI-PROJECT-21H02654
  • [Journal Article] Neural and behavioral control in Caenorhabditis elegans by a yellow-light?activatable caged compound2021

    • Author(s)
      Takahashi Hironori、Kamiya Mako、Kawatani Minoru、Umezawa Keitaro、Ukita Yoshiaki、Niwa Shinsuke、Oda Toshiyuki、Urano Yasuteru
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 6

    • DOI

      10.1073/pnas.2009634118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04738, KAKENHI-PLANNED-20H05724, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-20H03247, KAKENHI-PROJECT-19K16291, KAKENHI-PROJECT-21H02654
  • [Journal Article] Interactions between mitochondria and endoplasmic reticulum in demyelinated axons2018

    • Author(s)
      Thai Truc Quynh、Nguyen Huy Bang、Sui Yang、Ikenaka Kazuhiro、Oda Toshiyuki、Ohno Nobuhiko
    • Journal Title

      Medical Molecular Morphology

      Volume: 印刷中 Issue: 3 Pages: 135-146

    • DOI

      10.1007/s00795-018-0212-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H05057, KAKENHI-PROJECT-16K18977
  • [Journal Article] A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1)2018

    • Author(s)
      Kubo Tomohiro、Hou Yuqing、Cochran Deborah A.、Witman George B.、Oda Toshiyuki
    • Journal Title

      Molecular Biology of the Cell

      Volume: 29 Issue: 9 Pages: 1060-1074

    • DOI

      10.1091/mbc.e17-11-0689

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15115, KAKENHI-PROJECT-17H05057
  • [Journal Article] CFAP70 Is a Novel Axoneme-Binding Protein That Localizes at the Base of the Outer Dynein Arm and Regulates Ciliary Motility.2018

    • Author(s)
      Shamoto N, Narita K. Kubo T, Oda T, Takeda S.
    • Journal Title

      Cells

      Volume: 7 Issue: 9 Pages: 1-12

    • DOI

      10.3390/cells7090124

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08511, KAKENHI-PROJECT-18K06824, KAKENHI-PROJECT-17H05057, KAKENHI-PROJECT-17K15115
  • [Journal Article] Chlamydomonas as a tool to study tubulin polyglutamylation2018

    • Author(s)
      Kubo Tomohiro、Oda Toshiyuki
    • Journal Title

      Microscopy

      Volume: 68 Issue: 1 Pages: 80-91

    • DOI

      10.1093/jmicro/dfy044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H05057, KAKENHI-PROJECT-17K15115
  • [Journal Article] Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly.2018

    • Author(s)
      Yamaguchi H, Oda T, Kikkawa M, Takeda H
    • Journal Title

      Elife

      Volume: 7

    • DOI

      10.7554/elife.36979

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H05057, KAKENHI-PROJECT-16H02502, KAKENHI-PLANNED-15H05859
  • [Journal Article] Three-dimensional Structural Labeling Microscopy of Cilia and Flagella2017

    • Author(s)
      Toshiyuki Oda
    • Journal Title

      Microscopy

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01202
  • [Journal Article] Three-dimensional structural labeling microscopy of cilia and flagella.2017

    • Author(s)
      Oda T.
    • Journal Title

      Microscopy

      Volume: 66 Issue: 4 Pages: 234-244

    • DOI

      10.1093/jmicro/dfx018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H05057
  • [Journal Article] Electrostatic interaction between polyglutamylated tubulin and the nexin?dynein regulatory complex regulates flagellar motility2017

    • Author(s)
      Kubo Tomohiro、Oda Toshiyuki
    • Journal Title

      Molecular Biology of the Cell

      Volume: 28 Issue: 17 Pages: 2260-2266

    • DOI

      10.1091/mbc.e17-05-0285

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15115, KAKENHI-PROJECT-17H05057
  • [Journal Article] Structure and function of outer dynein arm intermediate and light chain complex.2016

    • Author(s)
      Oda T, Abe T, Yanagisawa H, Kikkawa M
    • Journal Title

      Molecular Biology of the Cell

      Volume: 27 Issue: 7 Pages: 1051-1059

    • DOI

      10.1091/mbc.e15-10-0723

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01202
  • [Journal Article] Docking complex-independent alignment of outer dynein arms with 24-nm periodicity in vitro.2016

    • Author(s)
      Oda T, Abe T, Yanagisawa H, Kikkawa M
    • Journal Title

      Journal of Cell Science

      Volume: 129 Issue: 8 Pages: 1547-1551

    • DOI

      10.1242/jcs.184598

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01202
  • [Journal Article] Identification of the outer-inner dynein linker as a hub controller for axonemal dynein activities.2013

    • Author(s)
      Oda T, Yagi T., H. Yanagisawa, Kikkawa M.
    • Journal Title

      Curr. Biol.

      Volume: 23 Issue: 8 Pages: 1-9

    • DOI

      10.1016/j.cub.2013.03.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570157, KAKENHI-PUBLICLY-23118706, KAKENHI-PROJECT-23770170
  • [Journal Article] Identification of the Outer-Inner Dynein Linker as a Hub Controller for Axonemal Dynein Activities.2013

    • Author(s)
      Oda, Toshiyuki, Yagi, T., Yanagisawa,H., and Kikkawa, M.
    • Journal Title

      Current Biology

      Volume: 23 Pages: 656-664

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770170
  • [Presentation] Evaluation of phlorizin's effects on gastrointestinal motility using a high-fat diet-induced mouse model2024

    • Author(s)
      志茂聡、坂本祐太、高木孝士、村松憲、小田賢幸、大野伸彦
    • Organizer
      第129回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-22K11815
  • [Presentation] Cryo-electron microscopy of uroplakin complex.2023

    • Author(s)
      小田賢幸
    • Organizer
      第79回日本顕微鏡学会学術講演会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05538
  • [Presentation] Cryo-electron microscopy of uroplakin complex.2023

    • Author(s)
      小田賢幸
    • Organizer
      第79回日本顕微鏡学会学術講演会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02654
  • [Presentation] 1型糖尿病モデルマウスにおける腸管筋層間神経叢の3次元微細構造解析2023

    • Author(s)
      志茂聡、坂本祐太、高木孝士、村松憲、小田賢幸、大野伸彦
    • Organizer
      第128回日本解剖学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K11815
  • [Presentation] 糖尿病性自律神経障害に対するフロリジンの消化管運動改善効果の検討2023

    • Author(s)
      志茂聡、坂本祐太、高木孝士、村松憲、小田賢幸、大野伸彦
    • Organizer
      第76回日本自律神経学会総会
    • Data Source
      KAKENHI-PROJECT-22K11815
  • [Presentation] Cryo-electron tomography of Birbeck granules reveals the molecular mechanism of langerin lattice formation2023

    • Author(s)
      小田賢幸
    • Organizer
      第128回日本解剖学会全国学術集会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02654
  • [Presentation] Cryo-electron tomography of Birbeck granules2022

    • Author(s)
      小田賢幸
    • Organizer
      第82回日本解剖学会中部支部学術集会
    • Data Source
      KAKENHI-PROJECT-21H02654
  • [Presentation] Cryo-electron tomography of Birbeck granules2022

    • Author(s)
      小田賢幸
    • Organizer
      第78回日本顕微鏡学会学術講演会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02654
  • [Presentation] Cryo-electron tomography of Birbeck granules.2022

    • Author(s)
      Toshiyuki Oda
    • Organizer
      The 78th Annual Meeting of the Japanese Society of Microscopy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02654
  • [Presentation] Cryo-electron tomography of cardiac myofibrils reveals a 3D lattice spring within the Z-discs2021

    • Author(s)
      Toshiyuki Oda
    • Organizer
      The 77th Annual Meeting of the Japanese Society of Microscopy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02654
  • [Presentation] 3D structural analysis of cilia using cryo-electron tomography2018

    • Author(s)
      Toshiyuki Oda
    • Organizer
      8th Asia Pacific International Congress of Anatomists
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05057
  • [Presentation] クライオ電子トモグラフィーによる繊毛モーターおよびチューブリン修飾の構造解析2018

    • Author(s)
      小田賢幸
    • Organizer
      機能タンパク質の構造と機能のダイナミクスと、 それに基づくく細胞・生体システム作動機構の研究拠点の形成 平成29年度末 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H05057
  • [Presentation] クライオ電顕の試料作製とデータ解析2018

    • Author(s)
      小田賢幸
    • Organizer
      第29回平成30年度電顕サマースクール
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H05057
  • [Presentation] Electrostatic interaction between polyglutamylated tubulin and the nexin-dynein regulatory complex regulates flagellar motility2017

    • Author(s)
      Oda T.
    • Organizer
      Dynein 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05057
  • [Presentation] クライオ電子トモグラフィーによる繊毛の三次元構造解析2017

    • Author(s)
      小田賢幸
    • Organizer
      第122回日本解剖学会総会・全国学術集会
    • Place of Presentation
      長崎大学坂本キャンパス(長崎県長崎市坂本)
    • Year and Date
      2017-03-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01202
  • [Presentation] Cryo-electron tomography of cilia2016

    • Author(s)
      小田賢幸
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市竹園)
    • Year and Date
      2016-11-26
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01202
  • [Presentation] クライオ電子トモグラフィーが明らかにした繊毛の運動と構築の分子メカニズム2015

    • Author(s)
      小田賢幸、柳澤春明、吉川雅英
    • Organizer
      第67回日本細胞生物学会大会
    • Place of Presentation
      タワーホール船堀( 東京都江戸川区)
    • Year and Date
      2015-07-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01202
  • [Presentation] The Outer-Inner Dynein Linker Regulates Flagellar Beating2012

    • Author(s)
      Toshiyuki Oda
    • Organizer
      American Society of Cell Biology Annual Meeting 2012
    • Place of Presentation
      Moscone Center, San Francisco, USA
    • Year and Date
      2012-12-18
    • Data Source
      KAKENHI-PROJECT-23770170
  • [Presentation] 外腕ダイニン中間鎖の構造的および機能的解析2011

    • Author(s)
      小田賢幸
    • Organizer
      第6回鞭毛・ダイニン機能研究会
    • Place of Presentation
      東京大学理学部2号館
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-23770170
  • [Presentation] Communication between Flagellar Outer and Inner Dynein Arms2011

    • Author(s)
      Toshiyuki Oda
    • Organizer
      American Society of Cell Biology Annual Meeting 2011
    • Place of Presentation
      Colorado Convention Center, Denver, USA
    • Year and Date
      2011-12-04
    • Data Source
      KAKENHI-PROJECT-23770170
  • [Presentation] Communication between Outer and Inner Dynein Arms

    • Author(s)
      小田賢幸、八木俊樹、吉川雅英
    • Organizer
      American Society for Cell Biology Annual Meeting
    • Place of Presentation
      Colorado Convention Center(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-23770170
  • [Presentation] 外腕ダイニン中間鎖の構造学的および機能的解析

    • Author(s)
      小田賢幸
    • Organizer
      第6回鞭毛・ダイニン研究会
    • Place of Presentation
      東京大学理学部(東京都)
    • Data Source
      KAKENHI-PROJECT-23770170
  • [Presentation] Communication between Outer and Inner Dynein Arms

    • Author(s)
      小田賢幸、八木俊樹、吉川雅英
    • Organizer
      第117回 日本解剖学会総会・全国学術集会
    • Place of Presentation
      山梨大学甲府キャンパス(山梨県甲府市)
    • Data Source
      KAKENHI-PROJECT-23770170
  • [Presentation] Outer-Inner Dynein Linker Regulates The Flagellar Beating

    • Author(s)
      Toshiyuki Oda
    • Organizer
      American Society of Cell Biology Annual Meeting
    • Place of Presentation
      Moscone Center, San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-23770170
  • 1.  Niwa Shinsuke (30714985)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  柳澤 春明 (70466803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  新森 英之 (40311740)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  志茂 聡 (80734607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  村松 憲 (00531485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  大野 伸彦 (10432155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  加藤 貴之 (20423155)
    # of Collaborated Projects: 1 results
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  • 8.  久住 聡 (00758039)
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  • 9.  NARITA Keishi
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  • 10.  久保 智広
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 11.  八木 俊樹
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  • 12.  竹田 扇
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  • 13.  吉川 雅英
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