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Matsuhira Takashi  松平 崇

… Alternative Names

MATSUHIRA Takashi  松平 崇

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Researcher Number 20570998
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-2429-9847
Affiliation (Current) 2025: 奈良県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2024: 奈良県立医科大学, 医学部, 講師
2011 – 2019: 奈良県立医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 90120:Biomaterials-related / Biomedical engineering/Biomaterial science and engineering / Polymer chemistry
Except Principal Investigator
Basic Section 90120:Biomaterials-related / Biomedical engineering/Biomaterial science and engineering
Keywords
Principal Investigator
ヘモグロビン / 高分子 / 血液代替物 / 人工臓器学 / 人工酸素運搬体 / 超分子重合 / 架橋 / 解離平衡 / 超分子化学 / 高分子科学 … More / 創傷被覆材 / 高分子ゲル / 星形ポリマー / ポリエチレングリコール / サブユニット間相互作用 / 超分子 / レオロジー / 開環重合 / 赤血球代替物 / 医療・福祉 / 生体材料 / 高分子合成 / SDS PAGE / 絹糸 / 電気泳動 / 分子量 / タンパク質 / 紫外線 / クモの糸 / 生体関連高分子 … More
Except Principal Investigator
一酸化炭素 / 蘇生液 / 輸血代替 / リポソーム / 虚血再灌流障害 / 組織酸素化 / DDS / 出血性ショック / 虚血再灌流傷害 / 人工酸素運搬体 / 人工臓器 / 酸化ストレス / 虚血 / 酸素輸送 / メチレンブルー / NADH / 解糖系酵素 / ヘモグロビン / 輸液 / 電子伝達系 / 人工赤血球 / 人工臓器学 Less
  • Research Projects

    (7 results)
  • Research Products

    (49 results)
  • Co-Researchers

    (4 People)
  •  Supramolecular hemoglobin hydrogel as a pro-healing dressing material for ischemic woundsPrincipal Investigator

    • Principal Investigator
      松平 崇
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Nara Medical University
  •  Resuscitation from hemorrhagic shock by carbon monoxide- and oxygen-carrying capacities of artificial red cells.

    • Principal Investigator
      Sakai Hiromi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Nara Medical University
  •  Starburst hemoglobin polymer with controlled physical properties as a red blood cell substitutePrincipal Investigator

    • Principal Investigator
      Matsuhira Takashi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Nara Medical University
  •  Synthesis and in vivo characterization of polymer-multilinked hemoglobin assembly as artificial oxygen carrierPrincipal Investigator

    • Principal Investigator
      Matsuhira Takashi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Nara Medical University
  •  Artificial red cells with a defense function to oxidative stress

    • Principal Investigator
      SAKAI HIROMI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Nara Medical University
  •  Synthesis of aligned megadalton hemoglobin assembly as artificial oxygen carrierPrincipal Investigator

    • Principal Investigator
      Matsuhira Takashi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Nara Medical University
  •  Study for elucidating the mechanism for the specific degradation of spider silk by ultraviolet raysPrincipal Investigator

    • Principal Investigator
      MATSUHIRA Takashi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Polymer chemistry
    • Research Institution
      Nara Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2013 2012 2011 Other

All Journal Article Presentation Book

  • [Book] Nanobiotherapeutics Based Blood Substitutes, Eds. T.M.S. Chang, J. Jahr, H, Sakai2020

    • Author(s)
      Takashi Matsuhira, Keizo Yamamoto, Hiromi Sakai
    • Publisher
      World Scientific Publishing Co. Pte. Ltd., Singapore
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Journal Article] ヘモグロビンとPEGが結合した巨大な環状モノマーの開環重合2023

    • Author(s)
      松平 崇・酒井宏水
    • Journal Title

      化学と工業

      Volume: 76(4) Pages: 261-261

    • Open Access
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Journal Article] Artificial oxygen carriers, from nanometer- to micrometer-sized particles, made of hemoglobin composites substituting for red blood cells2022

    • Author(s)
      Matsuhira Takashi、Sakai Hiromi
    • Journal Title

      Particuology

      Volume: 64 Pages: 43-55

    • DOI

      10.1016/j.partic.2021.08.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H03824, KAKENHI-PROJECT-21K12688
  • [Journal Article] ヘモグロビンとPEGが結合した巨大な環状モノマーの開環重合2022

    • Author(s)
      松平 崇, 酒井 宏水
    • Journal Title

      化学と工業

      Volume: 76 Pages: 261-261

    • Open Access
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Journal Article] 超分子重合を利用した人工酸素運搬体の構築2021

    • Author(s)
      松平崇、山本惠三、酒井宏水
    • Journal Title

      人工血液

      Volume: 29(1) Pages: 50-56

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Journal Article] Entropy-Driven Supramolecular Ring-Opening Polymerization of a Cyclic Hemoglobin Monomer for Constructing a Hemoglobin?PEG Alternating Polymer with Structural Regularity2021

    • Author(s)
      Matsuhira Takashi、Sakai Hiromi
    • Journal Title

      Biomacromolecules

      Volume: 22 Issue: 5 Pages: 1944-1954

    • DOI

      10.1021/acs.biomac.1c00061

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Journal Article] Ring-opening polymerization of hemoglobin.2019

    • Author(s)
      T. Matsuhira, K. Yamamoto, H. Sakai
    • Journal Title

      Biomacromolecules

      Volume: 20(4) Issue: 4 Pages: 1592-1602

    • DOI

      10.1021/acs.biomac.8b01789

    • NAID

      120007026512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K01367, KAKENHI-PROJECT-17K09018
  • [Journal Article] Antioxidative Pseudoenzymatic Mechanism of NAD(P)H Coexisting with Oxyhemoglobin for Suppressed Methemoglobin Formation2019

    • Author(s)
      Magohei Yamada, Takashi Matsuhira, Keizo Yamamoto, Hiromi Sakai
    • Journal Title

      Biochemistry

      Volume: 58 Issue: 10 Pages: 1400-1410

    • DOI

      10.1021/acs.biochem.8b01314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09018, KAKENHI-PROJECT-17H02087
  • [Journal Article] Analysis of dimeric αβ subunit exchange between PEGylated and native hemoglobins (α2β2 tetramer) in an equilibrated state by intramolecular ββ-crosslinking.2018

    • Author(s)
      T. Matsuhira, T. Kure, K. Yamamoto, H. Sakai
    • Journal Title

      Biomacromolecules

      Volume: 19(8) Issue: 8 Pages: 3412-3420

    • DOI

      10.1021/acs.biomac.8b00728

    • NAID

      120007026511

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K01367, KAKENHI-PROJECT-17K09018
  • [Journal Article] Effects of UV irradiation on the molecular weight of spider silk2013

    • Author(s)
      Takashi Matsuhira, Keizo Yamamoto and Shigeyoshi Osaki
    • Journal Title

      Polymer Journal

      Volume: 45 Issue: 11 Pages: 1167-1169

    • DOI

      10.1038/pj.2013.41

    • NAID

      40019844671

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23750133, KAKENHI-PROJECT-24655105, KAKENHI-PROJECT-25288102, KAKENHI-PROJECT-25670276, KAKENHI-PROJECT-25670277
  • [Journal Article] Why does the spider silk show the high resistivity of UV Rays?2011

    • Author(s)
      Takashi Matsuhira, Keizo Yamamoto, Shigeyoshi Osaki
    • Journal Title

      Proceedings of the 5^<th> International Peptide Symposium

      Volume: (ISBN: 978-4-931541-11-5) Pages: 277-277

    • NAID

      10028238177

    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] ヘモグロビンのサブユニット間相互作用により架橋された超分子ポリマーゲルの粘弾性スイッチング2024

    • Author(s)
      松平崇 , 酒井宏水
    • Organizer
      第35回 高分子ゲル研究討論会
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Presentation] ヘモグロビンのサブユニット間相互作用を利用した超分子重合2023

    • Author(s)
      松平崇 , 酒井宏水
    • Organizer
      第20回ホスト-ゲスト・超分子化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Presentation] ヘモグロビンを架橋点に持つ超分子ポリマーゲルの刺激応答性2023

    • Author(s)
      松平 崇 , 酒井 宏水
    • Organizer
      第30回血液代替物学会年次大会
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Presentation] Supramolecular hemoglobin-PEG alternating polymers constructed through non-covalent interactions between αβ subunits2023

    • Author(s)
      Takashi Matsuhira , Hiromi Sakai
    • Organizer
      The 13th SPSJ International Polymer Conference (IPC2023)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Presentation] 二個のヘモグロビンが四分岐PEGに結合した二環式モノマーの合成と超分子開環重合による可逆的な自己組織化2022

    • Author(s)
      松平 崇, 酒井 宏水
    • Organizer
      第29回日本血液代替物学会年次大会
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Presentation] ヘモグロビンを四分岐PEGで分子間架橋した超分子ゲルの合成とレオロジー特性2022

    • Author(s)
      松平 崇, 酒井 宏水
    • Organizer
      第45回日本バイオレオロジー学会年会
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Presentation] Rheological properties of supramolecular hydrogel composed of hemoglobin and four-armed PEG2022

    • Author(s)
      Takashi Matsuhira, Hiromi Sakai
    • Organizer
      第71回高分子討論会
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Presentation] 四分岐PEGを用いたヘモグロビンハイドロゲルの構築2021

    • Author(s)
      松平崇、酒井宏水
    • Organizer
      第28回血液代替物学会年次大会
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Presentation] エントロピー駆動型超分子開環重合を利用したヘモグロビン-PEG交互重合体の合成2021

    • Author(s)
      松平崇、酒井宏水
    • Organizer
      第70回高分子討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K12688
  • [Presentation] Quantification of Hybrid α2β2 Tetramer Formed by Spontaneous Exchange of Dimeric αβ Subunits between PEGylated and Native Hemoglobins Using Intra-Molecular Cross-Linking2019

    • Author(s)
      Takashi MATSUHIRA, Keizo YAMAMOTO, Hiromi SAKAI
    • Organizer
      The 17th International Symposium of Blood Substitutes & Oxygen Therapeutics (XVII-ISBS-2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] 環状ヘモグロビンモノマーの超分子開環重合における環サイズの影響2019

    • Author(s)
      松平崇、山本惠三、酒井宏水
    • Organizer
      第68回高分子討論会
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] Supramolecular Ring-Opening Polymerization of Hemoglobin and Subsequent Fixation Using Site-Specific Cross-Linking within α2β2 Tetramers2019

    • Author(s)
      Takashi MATSUHIRA, Keizo YAMAMOTO, Hiromi SAKAI
    • Organizer
      The 17th International Symposium of Blood Substitutes & Oxygen Therapeutics (XVII-ISBS-2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] Covalent Fixing of Supramolecular Hemoglobin Polymer Using Site-Selective Intra-Molecular Subunit Cross-Linking2019

    • Author(s)
      Takashi MATSUHIRA, Keizo YAMAMOTO, Hiromi SAKAI
    • Organizer
      15th International Symposium on Applied Bioinorganic Chemistry (ISABC15)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] Physicochemical characterization of poly-(PEG-hemoglobin) produced by ring-opening polymerization2018

    • Author(s)
      Takashi Matsuhira, Keizo Yamamoto, and Hiromi Sakai
    • Organizer
      第67回高分子討論会
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] ヘモグロビンとPEG 修飾ヘモグロビンのサブユニット交換平衡2018

    • Author(s)
      松平 崇・久禮 智子・山本 惠三・酒井 宏水
    • Organizer
      日本化学会 第98春季年会 (2018)
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] ヘモグロビンとNAD(P)Hとの共存により生じる抗酸化作用の機序2018

    • Author(s)
      山田孫平、松平崇、山本恵三、酒井宏水
    • Organizer
      日本化学会第98春季年会
    • Data Source
      KAKENHI-PROJECT-17H02087
  • [Presentation] 化学修飾ヘモグロビンのαβサブユニット交換反応2018

    • Author(s)
      松平 崇、久禮 智子、山本 惠三、酒井 宏水
    • Organizer
      日本血液代替物学会 第25回年次大会
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] Ring-opening polymerization of loop-PEGylated hemoglobin2018

    • Author(s)
      Takashi Matsuhira, Keizo Yamamoto, and Hiromi Sakai
    • Organizer
      第67回高分子学会年次大会
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] Ring-opening Polymerization of Hemoglobin Using its Reversible Association-Dissociation Equilibrium of α2β2 Subunits2018

    • Author(s)
      Takashi Matsuhira, Keizo Yamamoto, and Hiromi Sakai
    • Organizer
      The International Symposium for Materials Scientists "Inspiration for Innovation by Interaction" (ISMS-III)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] Reactivity of Cys beta93 of native and beta-crosslinked Hbs2017

    • Author(s)
      Takashi Matsuhira, Keizo Yamamoto, Hiromi Sakai
    • Organizer
      60th Anniversary of Artificial Cell in conjunction with XVI ISBS International Symposium Blood Substitutes & Oxygen Therapeutics V ISNS Nanomedicine Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] 四分岐PEG鎖で分子間架橋されたヘモグロビン集合体の合成と性質2017

    • Author(s)
      松平 崇・山田 孫平・久禮 智子・山本 惠三・酒井 宏水
    • Organizer
      日本化学会 第97春季年会
    • Place of Presentation
      慶應義塾大学 日吉キャンパス
    • Year and Date
      2017-03-16
    • Data Source
      KAKENHI-PROJECT-26750149
  • [Presentation] 分子間架橋したヘモグロビン集合体の作製と人工酸素運搬体としての性質2017

    • Author(s)
      松平 崇、山本 惠三、酒井 宏水
    • Organizer
      日本バイオマテリアル学会関西ブロック 第12回若手研究発表会
    • Data Source
      KAKENHI-PROJECT-17K01367
  • [Presentation] 天然のクモ糸の分子量は一体いくらなのか?2013

    • Author(s)
      大﨑茂芳、松平崇、山本惠三
    • Organizer
      第62回高分子討論会
    • Place of Presentation
      金沢大学 角間キャンパス
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] クモの糸の分子量はさらに大きかった2013

    • Author(s)
      松平 崇、大崎茂芳
    • Organizer
      第62回高分子討論会
    • Place of Presentation
      金沢大学 角間キャンパス
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] クモの糸の分子量はさらに大きかった2013

    • Author(s)
      松平崇,大崎茂芳
    • Organizer
      第62回高分子討論会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] 天然のクモ糸の分子量は一体いくらなのか?2013

    • Author(s)
      大崎茂芳,松平崇
    • Organizer
      第62回高分子討論会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] Effects of UV Rays upon Molecular Weight of Spider Silk2012

    • Author(s)
      Takashi Matsuhira, Shigeyoshi Osaki
    • Organizer
      Joint Symposium, 5th International Symposium on Polymer Materials Science (ISPMS'12) & 8th Osaka University Macromolecular Symposium (OUMS'12)
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] クモの糸タンパク質は多量体か?2012

    • Author(s)
      松平崇,大崎茂芳
    • Organizer
      第61回高分子学会年次大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] クモの糸の分子量に対する紫外線の影響2012

    • Author(s)
      松平崇,大崎茂芳
    • Organizer
      第61回高分子討論会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] Effects of UV Rays upon Molecular Weight of Spider Silk2012

    • Author(s)
      Takashi Matsuhira, Shigeyoshi Osaki
    • Organizer
      The 9th SPSJ International Polymer Conference (IPC2012)
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] 高分子量のクモの糸タンパク2011

    • Author(s)
      松平崇,大崎茂芳
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] クモ糸のタンパク質の分子量2011

    • Author(s)
      ○松平崇、大崎茂芳
    • Organizer
      第60回高分子年次大会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] クモ糸のタンパク質の分子量2011

    • Author(s)
      松平崇,大崎茂芳
    • Organizer
      第60回高分子学会年次大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] 高分子量のクモの糸タンパク2011

    • Author(s)
      ○松平崇、大崎茂芳
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山大学 津島キャンパス
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] Effects of UV Rays upon Molecular Weight of Spider Silk

    • Author(s)
      Takashi Matsuhira and Shigeyoshi Osaki
    • Organizer
      Joint Symposium, 5th International Symposium on Polymer Materials Science (ISPMS'12) & 8th Osaka University Macromolecular Symposium (OUMS'12)
    • Place of Presentation
      大阪大学(豊中キャンパス)
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] クモの糸タンパク質は多量体か?

    • Author(s)
      ○松平崇 大崎茂芳
    • Organizer
      第61回高分子学会年次大
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] Effects of UV Rays upon Molecular Weight of Spider Silk

    • Author(s)
      Takashi Matsuhira and Shigeyoshi Osaki
    • Organizer
      The 9th SPSJ International Polymer Conference (IPC2012)
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-23750133
  • [Presentation] クモの糸の分子量に対する紫外線の影響

    • Author(s)
      ○松平崇 大崎茂芳
    • Organizer
      第61回高分子討論会
    • Place of Presentation
      名古屋工業大学
    • Data Source
      KAKENHI-PROJECT-23750133
  • 1.  SAKAI HIROMI (70318830)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 30 results
  • 2.  山本 惠三 (90254490)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  山田 孫平 (90839317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  浅田 秀夫 (60252681)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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