otani naoki 大谷直樹

… Alternative Names

OTANI naoki 大谷直樹

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Researcher Number	20573637
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 教授 2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院脳神経外科, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 日本大学, 医学部, 准教授 2016 – 2020: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院脳神経外科, 講師 2016: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 病院脳神経外科, 講師 2015: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, その他部局等, 講師 2015: 防衛医科大学校, その他部局等, 講師 2013 – 2014: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 病院, 講師 2013: 防衛医科大学校, 病院, 講師
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Biomedical engineering/Biomaterial science and engineering / Medical systems
Keywords	Principal Investigator 脳神経外科 / basic FGF / 止血 / 髄液漏 / hemostasis / traumatic brain injury / CSF leakage / 脳神経外科手術 / 動脈止血 / 静脈止血 … More / 硬膜形成 / くも膜形成 / 光ゲル化剤 / 術中診断 / 超音波エコー / 画像診断 / 頭蓋内診断 / 脳血管 / 脳出血 / 脳血管障害 / 光音響技術 / 頸動脈プラーク / 脳腫瘍 / 脳血行再建 / 手術支援 / 手術機器 / 脳外科手術 / 光音響画像 / 顕微鏡下手術 … More Except Principal Investigator pH イメージング / 脳卒中後てんかん / 脳梗塞 / 酸感受性イオンチャネル / 再灌流傷害 / pH制御 / 正常酸素療法 / HMGB 1 / benign oligemia / metabolic penumbra / 酸感受性チャネル / Epac / pH / 脳血管障害 / 生理活性 / 生体分子 / トランスレーショナルリサーチ / シグナル伝達 / 基礎腫瘍学 / 胚細胞腫 / 動物モデル / 分子シグナル / NGGCT / ジャーミノーマ / c-KIT変異 / 中枢性胚細胞腫 / 脱ユビキチン化酵素 / ドライバー変異 / 非ジャーミノーマ性胚細胞腫瘍 / MEK1/2 / ユビキチン化 / USP28 / 非ジャーミノーマ胚細胞腫瘍 / 頭蓋内胚細胞腫瘍 / マグネシウム / 水素 / 脳血管攣縮 / くも膜下出血 / 皮下腫瘍マウス / 血管形成術 / 応力緩和時間 / チタンサファイアレーザー / 高速フーリエ変換 / CD31免疫染色 / 皮下腫瘍モデルマウス / CD３４免疫染色 / 微小血管 / 医師主体の臨床研究 / 血液酸素飽和度 / マルチスペクトル / ヘモグロビン / トモグラフィ / 光超音波画像 Less

pH変化を介した脳卒中後てんかん発症メカニズムの解明と新たな予防戦略の開発
- Principal Investigator
  
  五十嵐崇浩
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nihon University
脳神経外科手術におけるb-FGF徐放化光ゲル化剤の有用性の検証と開発Principal Investigator
- Principal Investigator
  
  大谷直樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nihon University
Molecular mechanism of pH-related ion channels in cerebral infarction using pH image
- Principal Investigator
  
  IGARASHI Takahiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nihon University
Identification of novel oncogenic mutations of a molecule which are specifically occurred in and regulate oncogenicity of intracranial non-germinomatous germ cell tumors
- Principal Investigator
  
  Tomiyama Arata
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  National Defense Medical College
Can a natural amino acid be used for diagnosis and treatment for arteriosclerosis
- Principal Investigator
  
  Morimoto Yuji
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Defense Medical College
Development of imaging method and novel clinical application for intraoperative diagnostic in microneurosurgery using photoacoustic imaging technologyPrincipal Investigator
- Principal Investigator
  
  OTANI NAOKI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  National Defense Medical College
Develop a wideband acoustic sensor for quantitative photoacoustic imaging
- Principal Investigator
  
  Ishihara Miya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  National Defense Medical College
A new system of brain protection using Hydrogen and Magnesium
- Principal Investigator
  
  Kentaro Mori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  National Defense Medical College

All 2024 2023 2018 2017 2016 2014 Other

All Journal Article Presentation

[Journal Article] 最新の神経イメージング：CEST-MRI技術を用いたpH imaging2024
- Author(s)
  五十嵐崇浩，梶本隆太，大島秀規，大谷直樹，吉野篤緒
- Journal Title
  
  細胞
  
  Volume: 56 Pages: 33-35
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09189
[Journal Article] Glibenclamide reduces secondary brain injury in a SAH rat model by reducing brain swelling and modulating inflammatory response2023
- Author(s)
  KAJIMOTO Ryuta、IGARASHI Takahiro、MORO Nobuhiro、OSHIMA Hideki、SUMA Takeshi、OTANI Naoki、YOSHINO Atsuo
- Journal Title
  
  Journal of Neurosurgical Sciences
  
  Volume: 67 Issue: 4 Pages: 431-438
- DOI
  10.23736/s0390-5616.22.05271-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09189
[Journal Article] Usefulness of dural surface tracing of the cortical vessels with indocyanine green videoangiography just prior to dural opening for various cerebrovascular diseases.2017
- Author(s)
  6.Otani N, Wada K, Toyooka T, Takeuchi S, Tomiyama A, Mori K
- Journal Title
  
  Surg Neurol Int.
  
  Volume: 22 Pages: 201-205
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10379
[Journal Article] 2.Flexible ultrathin endoscope integrated with irrigation suction apparatus for assisting micro- neurosurgery.2017
- Author(s)
  Otani N, Morimoto Y, Fujii K, Toyooka T, Wada K, Mori K.
- Journal Title
  
  World Neurosurg.
  
  Volume: 108 Pages: 589-594
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10379
[Journal Article] Flexible Ultrathin Endoscope Integrated with Irrigation Suction Apparatus for Assisting Microneurosurgery2017
- Author(s)
  Otani Naoki、Morimoto Yuji、Fujii Kazuya、Toyooka Terushige、Wada Kojiro、Mori Kentaro
- Journal Title
  
  World Neurosurgery
  
  Volume: 108 Pages: 589-594
- DOI
  10.1016/j.wneu.2017.09.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K12885
[Journal Article] Photoacoustic imaging system for peripheral small vessel imaging based on clinical ultrasound technology2016
- Author(s)
  Irisawa K, Hirota K, Hashimoto A, Murakoshi D, Ishii H, Tada T, Otani N, Ishihara M
- Journal Title
  
  SPIE proceeding
  
  Volume: 9708 Pages: 55-60
- NAID
  40021224564
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10379
[Journal Article] マグネシウム溶液脳槽内投与および水素水静脈内投与の併用療法がラットの生理的パラメーターに及ぼす影響について2014
- Author(s)
  戸村哲、藤井和也、上野英明、富山新太、大谷直樹、長田秀夫、和田孝次郎、森健太郎
- Journal Title
  
  防衛医科大学校雑誌
  
  Volume: 39
- NAID
  40021819707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462239
[Journal Article] Uncooled infrared camera for the noninvasive visualization of the vascular flow in an anastomotic vessel during neurosurgical surgery2014
- Author(s)
  Naoki Otani, Miya Ishihara, Masanori Fujita, Kojiro Wada, Kentaro Mori
- Journal Title
  
  Surgical Neurology International
  
  Volume: 35 Issue: 1 Pages: 223-226
- DOI
  10.4103/2152-7806.142034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282158
[Presentation] 脳血管障害とスルホニルウレア受容体：炎症性反応、免疫反応、そしてEpacとの関連について2023
- Author(s)
  五十嵐崇浩、筧雄三、塩川諒治、梶本隆太、大島秀規、大谷直樹、Kimberly T William 、Sheth N Kevin、吉野篤緒
- Organizer
  STROKE2023
- Data Source
  KAKENHI-PROJECT-21K09189
[Presentation] ラット脳梗塞モデルにおける神経細胞死に対するEpac2の影響2023
- Author(s)
  筧雄三, 五十嵐崇浩, 梶本隆太, 児玉智信, 大島秀規, 大谷直樹, 吉野篤緒
- Organizer
  第66回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09189
[Presentation] 脳神経外科手術における光音響画像技術の応用2018
- Author(s)
  大谷直樹、石原美弥、平沢壮、竹内誠、豊岡輝繁、和田孝次郎、森健太郎
- Organizer
  第４１回日本脳神経ＣＩ学会総会
- Data Source
  KAKENHI-PROJECT-15K10379
[Presentation] irrigation suction systemに統合した極細軟性内視鏡の脳外科顕微鏡手術への応用2018
- Author(s)
  大谷直樹、豊岡輝繁、竹内誠、和田孝次郎、森健太郎
- Organizer
  第２７回脳神経外科手術と機器学会
- Data Source
  KAKENHI-PROJECT-15K10379
[Presentation] Photoacoustic imaging system for peripheral small vessel imaging based on clinical ultrasound technology2016
- Author(s)
  Irisawa K, Hirota K, Hashimoto A, Murakoshi D, Ishii H, Tada T, Otani N, Ishihara M
- Organizer
  光音響国際学会
- Place of Presentation
  USA
- Year and Date
  2016-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10379
[Presentation] マグネシウム脳槽潅流および水素水静脈内投与の併用療法がくも膜下出血モデルラットの脳圧等に及ぼす影響
- Author(s)
  戸村哲、藤井和也、上野英明、富山新太、大谷直樹、長田秀夫、和田孝次郎、森健太郎
- Organizer
  第30回スパズム・シンポジウム
- Place of Presentation
  大阪国際会議場（大阪）
- Data Source
  KAKENHI-PROJECT-25462239

1. Ishihara Miya (30505342)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. Kentaro Mori (30200364)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. KUSHIBIKI Toshihiro (30403158)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. WADA kojiro (70649409)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. IGARASHI Takahiro (20468747)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 大島秀規 (20328735)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. ISHIHARA Masayiki (10508500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. HORIGUCHI Akio (20286553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TSUDA Hitoshi (70217321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HATTORI Hidemi (80508549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Tomiyama Arata (40385810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Morimoto Yuji (10449069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 藤田真敬 (20525927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 平沢壮 (60583086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 山本祐太朗 (20785761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 萩沢康介 (50539244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 須磨健 (20526115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 梶本隆太 (90883041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. 浅野正岳 (10231896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 吉野篤緒 (50256848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 児玉智信 (70449932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 四條克倫 (90800433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

otani naoki 大谷 直樹

OTANI naoki 大谷 直樹

Research Projects

Research Products

Co-Researchers

pH変化を介した脳卒中後てんかん発症メカニズムの解明と新たな予防戦略の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳神経外科手術におけるb-FGF徐放化光ゲル化剤の有用性の検証と開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of pH-related ion channels in cerebral infarction using pH image

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel oncogenic mutations of a molecule which are specifically occurred in and regulate oncogenicity of intracranial non-germinomatous germ cell tumors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Can a natural amino acid be used for diagnosis and treatment for arteriosclerosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of imaging method and novel clinical application for intraoperative diagnostic in microneurosurgery using photoacoustic imaging technologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Develop a wideband acoustic sensor for quantitative photoacoustic imaging

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A new system of brain protection using Hydrogen and Magnesium

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 最新の神経イメージング：CEST-MRI技術を用いたpH imaging2024

Author(s)

Journal Title

Data Source

[Journal Article] Glibenclamide reduces secondary brain injury in a SAH rat model by reducing brain swelling and modulating inflammatory response2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Usefulness of dural surface tracing of the cortical vessels with indocyanine green videoangiography just prior to dural opening for various cerebrovascular diseases.2017

Author(s)

Journal Title

Data Source

[Journal Article] 2.Flexible ultrathin endoscope integrated with irrigation suction apparatus for assisting micro- neurosurgery.2017

Author(s)

Journal Title

Data Source

[Journal Article] Flexible Ultrathin Endoscope Integrated with Irrigation Suction Apparatus for Assisting Microneurosurgery2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Photoacoustic imaging system for peripheral small vessel imaging based on clinical ultrasound technology2016

Author(s)

Journal Title

NAID

Data Source

otani naoki 大谷直樹

OTANI naoki 大谷直樹

[Presentation] ラット脳梗塞モデルにおける神経細胞死に対するEpac2の影響2023