SUGIYAMA MASAYA 杉山真也

… Alternative Names

Sugiyama Masaya 杉山真也

SUGIYAMA Masasya 杉山真也

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Researcher Number	20612427
Other IDs	https://orcid.org/0000-0002-9084-7197
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立国際医療研究所肝炎・免疫研究センター, テニュアトラック部長
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人国立国際医療研究センター, その他部局等, テニュアトラック部長 2017 – 2021: 国立研究開発法人国立国際医療研究センター, その他部局等, 副プロジェクト長 2017: 国立国際医療研究センター, 肝炎・免疫研究センター 2015: 国立研究開発法人国立国際医療研究センター, その他部局等, その他 2015: 国立研究開発法人国立国際医療研究センター, その他部局等, 主任研究員 … More 2012 – 2014: 独立行政法人国立国際医療研究センター, その他部局等, その他 2011 – 2013: 国立国際医療研究センター, 肝炎・免疫研究センター, 上級研究員 2012: 独立行政法人国立国際医療研究センター, 上級研究員 2012: 独立行政法人国立国際医療研究センター, 肝炎・免疫研究センター, 肝疾患研究部 2011: 独立行政法人国立国際医療研究センター, 肝炎・免疫研究センター, 上級研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Virology Except Principal Investigator Gastroenterology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Hygiene and public health / Virology
Keywords	Principal Investigator B型肝炎ウイルス / 肝線維化 / 受容体 / 侵入 / 感染 / 自然免疫 / 複製 / 動物モデル / 感染モデル / 生活環 … More / 感染経路 / Ｂ型肝炎ウイルス / 腸内細菌 / 単球 / ヒト肝細胞置換キメラマウス / 超解像 / 線維化 / マウスモデル / マクロファージ / B型肝炎 / ヒト化マウス / ヒト肝細胞キメラマウス / 細胞周期 / 活性酸素種 … More Except Principal Investigator B型慢性肝炎 / ジェノタイプ / 次世代シーケンサー / SNPs / 慢性化 / B型急性肝炎 / 背景肝疾患 / 微小血管浸潤 / データベース / シングルセル解析 / 肝細胞癌 / CD4T細胞 / 免疫寛容 / 自己免疫疾患 / 細胞リプログラミング / 制御性T細胞 / 免疫学 / 薬剤耐性ウイルス / ウイルス肝炎 / 薬剤耐性 / インターフェロン・フリー治療 / 開発途上国 / 医療・福祉 / 感染症 / 肝炎ウイルス / 慢性C型肝炎 / 慢性B型肝炎 / DAAs / C型慢性肝炎 / 薬剤耐性変異ウイルス / 核酸アナログ製剤 / quasispecies / genotype A / 遺伝子変異 / HLA / 急性肝炎 / B型肝炎 / 受容体 / 進化 / シグナル伝達 / 転写 / インターフェロンラムダ / HLA-DP / GWAS / HBV Less

B型肝炎ウイルスの感染侵入に関わる分子機序の解明Principal Investigator
- Principal Investigator
  
  杉山真也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  National Center for Global Health and Medicine
ナイーブT細胞の不均一性に着目した組織特異的免疫応答の解明および免疫制御法の開発
- Principal Investigator
  
  関谷高史
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  National Center for Global Health and Medicine
Elucidation of pathology and development of a new treatment for hepatocellular carcinoma through single-cell analysis
- Principal Investigator
  
  國土貴嗣
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Center for Global Health and Medicine
Research for analysis of receptor gene used by hepatitis B virusPrincipal Investigator
- Principal Investigator
  
  Sugiyama Masaya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  National Center for Global Health and Medicine
Research on effect of macrophage on liver fibrosis in a mouse model of hepatitis BPrincipal Investigator
- Principal Investigator
  
  Sugiyama Masaya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  National Center for Global Health and Medicine
Survey on the measures against viral hepatitis in developing countries of Asia and Africa
- Principal Investigator
  
  MASAKI NAOHIKO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  National Center for Global Health and Medicine
Molecular basis of liver fibrosis progression in humanized mouse model infected with HBVPrincipal Investigator
- Principal Investigator
  
  Sugiyama Masaya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  National Center for Global Health and Medicine
Development of the method for the prevention of the chronicity of hepatitis B virus infection using two types of next generation sequencer
- Principal Investigator
  
  ITO Kiyoaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Aichi Medical University
Response and specific function of IFN-lambda3 against infectious diseases
- Principal Investigator
  
  MIZOAKMI Masashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Research Institute, International Medical Center of Japan
Analyses on the progression of liver fibrosis induced by hepatitis B virus infectionPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Masaya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Gastroenterology
- Research Institution
  Research Institute, International Medical Center of Japan
Investigation the mechanisms of chronicity from acute hepatitis B using a next generation sequencer
- Principal Investigator
  
  ITO Kiyoaki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Research Institute, International Medical Center of Japan

All 2024 2022 2020 2019 2018 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Book Patent

[Book] ゲノムワイド関連解析とその応用2011
- Author(s)
  杉山真也、溝上雅史
- Total Pages
  6
- Publisher
  新時代のウイルス性肝炎学
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Prolyl Isomerase Pin1 Regulates the Stability of Hepatitis B Virus Core Protein.2020
- Author(s)
  Nishi M, Miyakawa K, Matsunaga S, Khatun H, Yamaoka Y, Watashi K, Sugiyama M, Kimura H, Wakita T, Ryo A.
- Journal Title
  
  Front Cell Dev Biol.
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18397
[Journal Article] A prospective trial of vaccine to prevent hepatitis B virus reactivation after hematopoietic stem cell transplantation.2020
- Author(s)
  Nishikawa K, Kimura K, Kanda Y, Sugiyama M, Kakihana K, Doki N, Ohashi K, Bae SK, Takahashi K, Ishihara Y, Mizuno I, Onishi Y, Onozawa M, Onizuka M, Yamamoto M, Ishikawa T, Inoue K, Kusumoto S, Hashino S, Saito H, Kanto T, Sakamaki H, Mizokami M
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: .
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18397
[Journal Article] Virological Factors Associated with the Occurrence of HBV Reactivation in Patients with Resolved HBV Infection Analyzed through Ultradeep Sequencing.2019
- Author(s)
  Sakamoto K, Umemura T, Ito K, Okumura A, Joshita S, Ota M, Sugiyama M, Mizokami M, Yoneda M, Tanaka E.
- Journal Title
  
  J Infect Dis.
  
  Volume: .
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18397
[Journal Article] Fairly rare small-diameter hepatocellular carcinoma with right adrenal gland metastasis having an inferior vena cava tumor thrombus: a case report.2019
- Author(s)
  Igarashi T, Harimoto N, Matsumura N, Sugiyama M, Araki K, Yokobori T, Kosone T, Takagi H, Aishima S, Yokoo H, Shirabe K.
- Journal Title
  
  Surg Case Rep.
  
  Volume: 5 Pages: 170-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18397
[Journal Article] Immunomodulatory mechanism of acyclic nucleoside phosphates in treatment of hepatitis B virus infection.2019
- Author(s)
  Murata K, Tsukuda S, Suizu F, Kimura A, Sugiyama M, Watashi K, Noguchi M, Mizokami M.
- Journal Title
  
  Hepatology.
  
  Volume: .
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18397
[Journal Article] Anti-Viral Effects of Interferon-λ3 on Hepatitis B Virus Infection in Cell Culture.2019
- Author(s)
  Yamada N, Murayama A, Shiina M, Aly HH, Iwamoto M, Tsukuda S, Watashi K, Tanaka T, Moriishi K, Nishitsuji H, Sugiyama M, Mizokami M, Shimotohno K, Muramatsu M, Murata K, Kato T.
- Journal Title
  
  Hepatol Res.
  
  Volume: .
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18397
[Journal Article] Cytokine and chemokine signatures associated with hepatitis B surface antigen loss in hepatitis B patients2018
- Author(s)
  Yoshio Sachiyo、Mano Yohei、Doi Hiroyoshi、Shoji Hirotaka、Shimagaki Tomonari、Sakamoto Yuzuru、Kawai Hironari、Matsuda Michitaka、Mori Taizo、Osawa Yosuke、Korenaga Masaaki、Sugiyama Masaya、Mizokami Masashi、Mita Eiji、Katayama Keiko、Tanaka Junko、Kanto Tatsuya
- Journal Title
  
  JCI Insight
  
  Volume: 3 Issue: 20 Pages: 122268-122268
- DOI
  10.1172/jci.insight.122268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03589, KAKENHI-PROJECT-17H04168, KAKENHI-PROJECT-17K18397
[Journal Article] Indoleamine-2,3-dioxygenase as an effector and an indicator of protective immune responses in patients with acute hepatitis B.2016
- Author(s)
  Yoshio S, Sugiyama M, Shoji H, Mano Y, Mita E, Okamoto T, Matsuura Y, Okuno A, Takikawa O, Mizokami M, Kanto T.
- Journal Title
  
  Hepatology
  
  Volume: 63 Issue: 1 Pages: 83-94
- DOI
  10.1002/hep.28282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08326, KAKENHI-PROJECT-25860574
[Journal Article] Seroprevalence of chronic hepatitis B, as determined from dried blood spots, among children and their mothers in central Lao People's Democratic Republic: A multistage, stratified cluster sampling survey.2015
- Author(s)
  Komada K, Sugiyama M, Vongphrachanh P, Xeuatvongsa A, Khamphaphongphane B, Kitamura T, Kiyohara T, Wakita T, Oshitani H, Hachiya M.
- Journal Title
  
  Int J Infect Dis.
  
  Volume: - Pages: 21-26
- DOI
  10.1016/j.ijid.2015.04.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860574
[Journal Article] Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression.2015
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Okada M, Sugiyama M, Kojima S, Tanaka Y, Mizokami M, Li J, Tong S, Wakita T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Issue: 9 Pages: 5673-84
- DOI
  10.1074/jbc.m114.602540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860574, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102741, KAKENHI-PUBLICLY-26102742
[Journal Article] Seroepidemiological study of hepatitis B virus markers in Japan2015
- Author(s)
  Kiyohara T., Ishii K., Sugiyama M., Mizokami M. and Wakita T.
- Journal Title
  
  Vaccine
  
  Volume: 33 Issue: 45 Pages: 6037-6042
- DOI
  10.1016/j.vaccine.2015.08.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460580, KAKENHI-PROJECT-25860574
[Journal Article] Use of nucleotide analogs in patients with chronic hepatitis B in Nepal: A prospective cohort study in a single hospital.2015
- Author(s)
  Masaki N, Shrestha PK, Nishimura S, Ito K, Sugiyama M, Mizokami M
- Journal Title
  
  Hepatol Res
  
  Volume: Jan 12 Issue: 12 Pages: 1163-1169
- DOI
  10.1111/hepr.12482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591002, KAKENHI-PROJECT-25860574, KAKENHI-PROJECT-15H05289
[Journal Article] Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells.2015
- Author(s)
  Okumura N, Ikeda M, Satoh S, Dansako H, Sugiyama M, Mizokami M, Kato N.
- Journal Title
  
  FEBS Lett.
  
  Volume: 589 Issue: 10 Pages: 1112-8
- DOI
  10.1016/j.febslet.2015.03.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860574, KAKENHI-PROJECT-15K08498
[Journal Article] Differential expression of CX3CL1 in HBV-replicating hepatoma cells could affect the migration-activity of CX3CR1+ immune cells.2015
- Author(s)
  Kondo Y, Kimura O, Tanaka Y, Ninomiya M, Iwata T, Kogure T, Inoue J, Sugiyama M, Morosawa T, Fujisaka Y, Shimosegawa T.
- Journal Title
  
  J Virol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860574
[Journal Article] IL28B polymorphisms and clinical implications for hepatitis C virus infection in Uzbekistan2014
- Author(s)
  Khudayberganova D, Sugiyama M, Masaki N, Nishida N, Mukaide M, Sekler D, Latipov R, Nataliya K, Dildora S, Sharapov S, Usmanova G, Raxmanov M, Musabaev E, Mizokami M
- Journal Title
  
  PLoS One
  
  Volume: 24;9 Issue: 3 Pages: e93011-e93011
- DOI
  10.1371/journal.pone.0093011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-24790728, KAKENHI-PROJECT-25860574, KAKENHI-PROJECT-25291103
[Journal Article] Ex vivo induction of IFN-λ3 by a TLR7 agonist determines response to Peg-IFN/ ribavirin therapy in chronic hepatitis C patients2014
- Author(s)
  Murata K, Sugiyama M, Kimura T, Yoshio S, Kanto T, Kirikae I, Saito H, Aoki Y, Hiramine S, Matsui T, Ito K, Korenaga M, Imamura M, Masaki N, Mizokami M
- Journal Title
  
  J Gastroenterol
  
  Volume: 49(1) Issue: 1 Pages: 126-37
- DOI
  10.1007/s00535-013-0814-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-25860574
[Journal Article] New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia.2014
- Author(s)
  Nishida N, Sawai H, Kashiwase K, Minami M, Sugiyama M, Seto WK, Yuen MF, Posuwan N, Poovorawan Y, Ahn SH, Han KH, Matsuura K, Tanaka Y, Kurosaki M, Asahina Y, Izumi N, Kang JK, （省略）, Tokunaga K, and Mizokami M
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 2 Pages: e86449-e86449
- DOI
  10.1371/journal.pone.0086449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22133008, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23390201, KAKENHI-PROJECT-23590985, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-24790728, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25461010, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-25860574, KAKENHI-PROJECT-25870178, KAKENHI-PROJECT-26461027, KAKENHI-PROJECT-26670378, KAKENHI-PROJECT-25291103
[Journal Article] Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)2014
- Author(s)
  Watashi K, Sluder A, Daito T, Matsunaga S, Ryo A, Nagamori S, Iwamoto M, Nakajima S, Tsukuda S, Borroto-Esoda K, Sugiyama M, Tanaka Y, Kanai Y, Kusuhara H, Mizokami M, Wakita T
- Journal Title
  
  Hepatology
  
  Volume: 59 Issue: 5 Pages: 1726-1737
- DOI
  10.1002/hep.26982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PUBLICLY-24102537, KAKENHI-ORGANIZER-24115001, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PUBLICLY-25136714, KAKENHI-PROJECT-25860574
[Journal Article] Chronic Hepatitis B Prevalence among Children and Mothers: Results from a Nationwide, Population-Based Survey in Lao People’s Democratic Republic.2014
- Author(s)
  Xeuatvongsa A., Komada K., Kitamura T., Vongphrachanh P., Pathammavong C., Phounphenghak K., Sisouk T., Phonekeo D., Sengkeopaseuth B., Som-Oulay V., Ishii K., Wakita T., Sugiyama M. and Hachiya M.
- Journal Title
  
  PLOS One
  
  Volume: 9 Issue: 2 Pages: e88829-e88829
- DOI
  10.1371/journal.pone.0088829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460580, KAKENHI-PROJECT-25860574
[Journal Article] Pretreatment prediction of the outcome of response-guided peginterferon-α and ribavirin therapy for chronic hepatitis C2014
- Author(s)
  Masaki N, Sugiyama M, Shimada N, Tanaka Y, Nakamuta M, Izumi N, Watanabe S, Tsubota A, Komatsu M, Masaki T, Enomoto N, Yoneda M, Murata K, Ito K, Koike K, Mizokami M.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 29 Issue: 12 Pages: 1996-2005
- DOI
  10.1111/jgh.12646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-24591002, KAKENHI-PROJECT-25461014
[Journal Article] Risk factors for long-term persistence of serum hepatitis B surface antigen following acute hepatitis B virus infection in Japanese adults2014
- Author(s)
  Ito K, Yotsuyanagi H, Yatsuhashi H, Karino Y, Takikawa Y, Saito T, Arase Y, Imazeki F, Kurosaki M, Umemura T, Ichida T, Toyoda H, Yoneda M, Mita E, Yamamoto K, Michitaka K, Maeshiro T, Tanuma J, Tanaka Y, Sugiyama M, Murata K, Masaki N, Mizokami M; Japanese AHB Study Group
- Journal Title
  
  Hepatology
  
  Volume: 59 Issue: 1 Pages: 89-97
- DOI
  10.1002/hep.26635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-24591002, KAKENHI-PROJECT-25860574
[Journal Article] Tracing the spread of hepatitis C virus in Turkey: a phylogenetic analysis.2013
- Author(s)
  Sunbul M, Khan A, Kurbanov F, Leblebicioglu H, Sugiyama M, Tanaka Y, Mizokami M.
- Journal Title
  
  Intervirology.
  
  Volume: 56 Issue: 3 Pages: 201-5
- DOI
  10.1159/000346775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860574
[Journal Article] 2'-Fluoro-6'-methylene-carbocyclic adenosine phosphoramidate (FMCAP) prodrug : In vitro anti-HBV activity against the lamivudine-entecavir resistant triple mutant and its mechanism of action.2013
- Author(s)
  Rawal RK, Singh US, Chavre SN, Wang J, Sugiyama M, Hung W, Govindarajan R, Korba B, Tanaka Y, Chu CK.
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: 15 Issue: 2 Pages: 503-6
- DOI
  10.1016/j.bmcl.2012.11.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255, KAKENHI-PROJECT-25860574
[Journal Article] Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus2013
- Author(s)
  Yoshio S, Kanto T, Kuroda S, Matsubara T, Higashitani K, Kakita N, Ishida H, Hiramatsu N, Nagano H, Sugiyama M, Murata K, Fukuhara T, Matsuura Y, Hayashi N, Mizokami M, Takehara T
- Journal Title
  
  Hepatology
  
  Volume: 57 Issue: 5 Pages: 1705-15
- DOI
  10.1002/hep.26182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-25460994, KAKENHI-PROJECT-25860574
[Journal Article] 2'-Fluoro-6'-methylene-carbocyclic adenosine phosphoramidate (FMCAP) prodrug: In vitro anti-HBV activity against the lamivudine-entecavir resistant triple mutant and its mechanism of action.2013
- Author(s)
  Rawal RK, Singh US, Chavre SN, Wang J, Sugiyama M, Hung W, Govindarajan R, Korba B, Tanaka Y, Chu CK
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: 23(2) Pages: 503-6
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Specific mutations of basal core promoter are associated with chronic liver disease in hepatitis B virus subgenotype D1 prevalent in Turkey.2013
- Author(s)
  Sunbul M, Sugiyama M, Kurbanov F, Leblebicioglu H, Khan A, Elkady A, Tanaka Y, Mizokami M.
- Journal Title
  
  Microbiol Immunol.
  
  Volume: 57 Issue: 2 Pages: 122-9
- DOI
  10.1111/1348-0421.12011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860574
[Journal Article] In vitro replication competence of a hepatitis B genotype D/A recombinant virus: dissimilar biological behaviour regarding its parental genotypes.2013
- Author(s)
  Trinks J, Sugiyama M, Tanaka Y, Kurbanov F, Benetucci J, Giménez E, Weissenbacher MC, Mizokami M, Oubiña JR.
- Journal Title
  
  J Gen Virol.
  
  Volume: 94 Issue: 12 Pages: 2724-8
- DOI
  10.1099/vir.0.053595-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860574
[Journal Article] No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.2012
- Author(s)
  Sawai H, Nishida N, Mbarek H, Matsuda K, Mawatari Y, Yamaoka M, Hige S, Kang JH, Abe K, Mochida S, Watanabe M, Kurosaki M, Asahina Y, Izumi N, Honda M, Kaneko S, Tanaka E, Matsuura K, Itoh Y, Mita E, Korenaga M, Hino K, Murawaki Y, Hiasa Y, Ide T, Ito K, Sugiyama M, Ahn SH, Han KH, Park JY, Yuen MF, Nakamura Y, Tanaka Y, Mizokami M, Tokunaga K
- Journal Title
  
  BMC Med Genet
  
  Volume: 13 Pages: 47-47
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Hepatitis C virus kinetics by administration of pegylated interferon-lin human and chimeric mice carrying human hepatocytes with variants of the IL28B gene2012
- Author(s)
  Watanabe T, Sugauchi F, Tanaka Y, Matsuura K, Yatsuhashi H, Murakami S, Iijima S, Iio E, Sugiyama M, Shimada T, Kakuni M, Kohara M, Mizokami M
- Journal Title
  
  Gut
  
  Volume: Nov 7 Issue: 9 Pages: 1340-6
- DOI
  10.1136/gutjnl-2012-302553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790664, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23790804, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-25860574
[Journal Article] 【 C 型肝炎個別化医療のための宿主因子, ウイルス因子】IL-28B 遺伝子周囲に存在する SNPs の機能解析2012
- Author(s)
  杉山真也, 溝上雅史
- Journal Title
  
  消化器内科
  
  Volume: 55 (2) Pages: 263-270
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma.2012
- Author(s)
  Kumar V, Yi Lo PH, Sawai H, Kato N, Takahashi A, Deng Z, Urabe Y, Mbarek H, Tokunaga K, Tanaka Y, Sugiyama M, Mizokami M, Muroyama R, Tateishi R, Omata M, Koike K, Tanikawa C, Kamatani N, Kubo M, Nakamura Y, Matsuda K
- Journal Title
  
  PLoS One
  
  Volume: 7(9)
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Hepatitis C virus kinetics by administration of pegylated interferon-α in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene.2012
- Author(s)
  Watanabe T, Sugauchi F, Tanaka Y, Matsuura K, Yatsuhashi H, Murakami S, Iijima S, Iio E, Sugiyama M, Shimada T, Kakuni M, Kohara M, Mizokami M
- Journal Title
  
  Gut
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Factors responsible for the discrepancy between IL28B polymorphism prediction and the viral response to peginterferon plus ribavirin therapy in Japanese chronic hepatitis C patients.2012
- Author(s)
  Saito H, Ito K, Sugiyama M, Matsui T, Aoki Y, Imamura M, Murata K, Masaki N, Nomura H, Adachi H, Hige S, Enomoto N, Sakamoto N, Kurosaki M, Mizokami M, Watanabe S
- Journal Title
  
  Hepatol Res.
  
  Volume: 42(10) Pages: 958-965
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.2012
- Author(s)
  Sawai H, Nishida N, Mbarek H, Matsuda K, Mawatari Y, Yamaoka M, Hige S, Kang JH, Abe K, Mochida S, Watanabe M, Kurosaki M, Asahina y Izumi N, Honda M, Kaneko S, Tanaka E, Matsuura K, Itoh Y, Mita E, Korenaga M, Hino K, Murawaki Y, Hiasa Y, Ide T, Ito K, Sugiyama M, Ahn SH, Han KH, Park JY, Yuen MF, Nakamura Y, Tanaka Y, Mizokami M, Tokunaga K.
- Journal Title
  
  BMC Med Genet.
  
  Volume: 19 Pages: 47-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Development of specific and quantitative real-time detection PCR and immunoassays for λ3-interferon2012
- Author(s)
  Sugiyama M, Kimura T, Naito S, Mukaide M, Shinauchi T, Ueno M, Ito K, Murata K, Mizokami M
- Journal Title
  
  Hepatol Res
  
  Volume: 42(11) Issue: 11 Pages: 1089-99
- DOI
  10.1111/j.1872-034x.2012.01032.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-23890255
[Journal Article] LecT-Hepa, a glyco-marker derived from multiple lectins, as a predictor of liver fibrosis in chronic hepatitis C patients2012
- Author(s)
  Ito K, Kuno A, Ikehara Y, Sugiyama M, Saito H, Aoki Y, Matsui T, Imamura M, Korenaga M, Murata K, Masaki N, Tanaka Y, Hige S, Izumi N, Kurosaki M, Nishiguchi S, Sakamoto M, Kage M, Narimatsu H, Mizokami M
- Journal Title
  
  Hepatology
  
  Volume: 56 Issue: 4 Pages: 1448-56
- DOI
  10.1002/hep.25815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-23890255, KAKENHI-PROJECT-24590498
[Journal Article] Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean.2012
- Author(s)
  Nishida N, Sawai H, Matsuura K, Sugiyama M, Ahn SH, Park JY, Hige S, Kang JH, Suzuki K, Kurosaki M, Asahina Y, Mochida S, Watanabe M, Tanaka E, Honda M, Kaneko S, Orito E, Itoh Y, Mita E, Tamori A, Murawaki Y, Hiasa Y, Sakaida I, Korenaga M, Hino K, Ide T, Kawashima M, Mawatari Y, Sageshima M, Ogasawara Y, Koike A, Izumi N, Han KH, Tanaka Y, Tokunaga K, Mizokami M
- Journal Title
  
  PLoS One
  
  Volume: 7(6)
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Present state and the future direction of HBV vaccine2012
- Author(s)
  Mizokami M, Sugiyama M.
- Journal Title
  
  Uirusu
  
  Volume: 62 Pages: 67-77
- NAID
  10030768091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region2012
- Author(s)
  Nakano T, Lau G M, Sugiyama M, Mizokami M
- Journal Title
  
  Liver Int
  
  Volume: 32 Pages: 339-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] LecT-hepa, a glyco-marker derived from multiple lectins, as a predictor of liver fibrosis in chronic hepatitis C patients.2012
- Author(s)
  Ito K, Kuno A, Ikehara Y, Sugiyama M, Saito H, Aoki Y, Matsui T, Imamura M, Korenaga M, Murata K, Masaki N, Tanaka Y, Hige S, Izumi N, Kurosaki M, Nishiguchi S, Sakamoto M, Kage M, Narimatsu H, Mizokami M.
- Journal Title
  
  Hepatology.
  
  Volume: 56(4) Pages: 1448-56
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Development of specific and quantitative real-time detection PCR and immunoassays for λ3-interferon.2012
- Author(s)
  Sugiyama M, Kimura T, Naito S, Mukaide M, Shinauchi T, Ueno M, Ito K, Murata K, Mizokami M
- Journal Title
  
  Hepatol Res.
  
  Volume: 42(11) Pages: 1089-99
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] 【 IL-20 以降の新しいインターロイキンの機能と関連疾患】IL-28A/B , IL-29 と疾患2012
- Author(s)
  杉山真也, 溝上雅史
- Journal Title
  
  細胞工学
  
  Volume: 31 (7) Pages: 782-786
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] Factors responsible for the discrepancy between IL28B polymorphism prediction and the viral response to peginterferon plus ribavirin therapy in Japanese chronic hepatitis C patients2012
- Author(s)
  Saito H, Ito K, Sugiyama M, Matsui T, Aoki Y, Imamura M, Murata K, Masaki N, Nomura H, Adachi H, Hige S, Enomoto N, Sakamoto N, Kurosaki M, Mizokami M, Watanabe S
- Journal Title
  
  Hepatol Res
  
  Volume: 42(10) Issue: 10 Pages: 958-65
- DOI
  10.1111/j.1872-034x.2012.01013.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-23890255, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
[Journal Article] Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean.2012
- Author(s)
  Nishida N, Sawai H, Matsuura K, Sugiyama M, Ahn SH, Park JY, Hige S, Kang JH, Suzuki K, Kurosaki M, Asahina Y, Mochida S, Watanabe M, Tanaka E, Honda M, Kaneko S, Orito E, Itoh Y, Mita E, Tamori A, Murawaki Y, Hiasa Y, Sakaida I, Korenaga M, Hino K, Ide T, Kawashima M, Mawatari Y, Sageshima M, Ogasawara Y, Koike A, Izumi N, Han KH, Tanaka Y, Tokunaga K, Mizokami M.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma.2012
- Author(s)
  Kumar V, Yi Lo PH, Sawai H, Kato N, Takahashi A, Deng Z, Urabe Y, Mbarek H, Tokunaga K, Tanaka Y, Sugiyama M, Mizokami M, Muroyama R, Tateishi R, Omata M, Koike K, Tanikawa C, Kamatani N, Kubo M, Nakamura Y, Matsuda K.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Easy-to-use phylogenetic analysis system for hepatitis B virus infection2011
- Author(s)
  Sugiyama M, Inui A, Shin-IT, Komatsu H, Mukaide M, Masaki N, Murata K, Ito K, Nakanishi M, Fujisawa T, Mizokami M
- Journal Title
  
  Hepatol Res
  
  Volume: 41(10) Issue: 10 Pages: 936-945
- DOI
  10.1111/j.1872-034x.2011.00859.x
- NAID
  10031144168
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22118003, KAKENHI-PROJECT-23240124, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-23890255
[Journal Article] Genome-wide association study and clinical application2011
- Author(s)
  Sugiyama M, Mizokami M
- Journal Title
  
  Nihon Rinsho
  
  Volume: 69 Pages: 80-85
- NAID
  40018838444
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] Novel findings for the development of drug therapy for various liver diseases : Genetic variation in IL-28B is associated with response to the therapy for chronic hepatitis C2011
- Author(s)
  Masaya Sugiyama, 他4名
- Journal Title
  
  Journal of Pharmacological Science
  
  Volume: 115 Pages: 263-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Host sphingolipid biosynthesis is a promising therapeutic target for the inhibition of hepatitis B virus replication2011
- Author(s)
  Tatematsu K, Mizokami M, et al
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 83 Issue: 4 Pages: 587-593
- DOI
  10.1002/jmv.21970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23890255
[Journal Article] Transmissibility of hepatitis B virus (HBV) infection through blood transfusion from blood donors with occult HBV infection.2011
- Author(s)
  Yuen MF, Wong DK, Lee CK, Tanaka Y, Allain JP, Fung J, Leung J, Lin CK, Sugiyama M, Sugauchi F, Mizokami M, Lai CL
- Journal Title
  
  Clin Infect Dis.
  
  Volume: 52(5) Pages: 624-32
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Genetic Variation of the IL-28B Promoter Affecting Gene Expression.2011
- Author(s)
  Sugiyama M, Tanaka Y, Wakita T, Nakanishi M, Mizokami M
- Journal Title
  
  PLoS ONE
  
  Volume: 6(10)
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] 【新時代のウイルス性肝炎学基礎・臨床研究の進歩】 C型肝炎 C 型肝炎ウイルス研究の進歩C 型肝炎ウイルス研究技術の進歩ゲノムワイド関連解析とその応用2011
- Author(s)
  杉山真也, 溝上雅史
- Journal Title
  
  日本臨床
  
  Volume: 69 Pages: 80-85
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors2011
- Author(s)
  Masayuki Kurosaki, Masaya Sugiyama, 他19名
- Journal Title
  
  Journal of Hepatology
  
  Volume: 54 Pages: 439-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B2011
- Author(s)
  Ito K, Higami K, Masaki N, Sugiyama M, Mukaide M, Saito H, Aoki Y, Sato Y, Imamura M, Murata K, Nomura H, Hige S, Adachi H, Hino K, Yatsuhashi H, Orito E, Kani S, Tanaka Y, Mizokami M
- Journal Title
  
  J Clin Microbiol
  
  Volume: 49 Issue: 5 Pages: 1853-60
- DOI
  10.1128/jcm.02139-10
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005
[Journal Article] An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region.2011
- Author(s)
  Nakano T, Lau GM, Lau GM, Sugiyama M, Mizokami M
- Journal Title
  
  Liver Int.
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Novel findings for the development of drug therapy for various liver diseases : Genetic variation in IL-28B is associated with response to the therapy for chronic hepatitis C2011
- Author(s)
  Sugiyama M, Mizokami M, et al
- Journal Title
  
  Journal of Pharmacological Science
  
  Volume: 115 Pages: 263-269
- NAID
  10029892326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] Antiviral activity of novel 2'-fluoro-6'-methylene-carbocyclic adenosine against wild-type and drug-resistant hepatitis B virus mutants.2011
- Author(s)
  Wang J, Singh US, Rawal RK, Sugiyama M, Yoo J, Jha AK, Scroggin M, Huang Z, Murray MG, Govindarajan R, Tanaka Y, Korba B, Chu CK
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 21(21) Pages: 6328-31
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Genetic variation of the IL-28B promoter affecting gene expression2011
- Author(s)
  Sugiyama M, Mizokami M, et al
- Journal Title
  
  PLoS ONE
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] Novel findings for the development of drug therapy for various liver diseases : Genetic variation in IL-28B is associated with response to the therapy for chronic hepatitis C2011
- Author(s)
  Sugiyama M, Tanaka Y, Nakanishi M, Mizokami M
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 115(3) Pages: 263-9
- NAID
  10029892326
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region2011
- Author(s)
  Nakano T, Mizokami M, et al
- Journal Title
  
  Liver International
  
  Volume: 32 Issue: 2 Pages: 339-345
- DOI
  10.1111/j.1478-3231.2011.02684.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23890255
[Journal Article] Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors.2011
- Author(s)
  Kurosaki M, Tanaka Y, Nishida N, Sakamoto N, Enomoto N, Honda M, Sugiyama M, Matsuura K, Sugauchi F, Asahina Y, Nakagawa M, Watanabe M, Sakamoto M, Maekawa S, Sakai A, Kaneko S, Ito K, Masaki N, Tokunaga K, Izumi N, Mizokami M
- Journal Title
  
  J Hepatol
  
  Volume: 54(3) Pages: 439-48
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Transmissibility of hepatitis B virus (HBV) infection through blood transfusion from blood donors with occult HBV infection2011
- Author(s)
  Man-Fung Yuen, Masaya Sugiyama, 他10名
- Journal Title
  
  Clinical Infectious Diseases
  
  Volume: 52 Pages: 624-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Easy-to-use phylogenetic analysis system for hepatitis B virus infection.2011
- Author(s)
  Sugiyama M, Inui A, Shin-I T, Komatsu H, Mukaide M, Masaki N, Murata K, Ito K, Nakanishi M, Fujisawa T, Mizokami M
- Journal Title
  
  Hepatol Res.
  
  Volume: 41(10) Pages: 936-45
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Antiviral activity of novel 2'-fluoro-6'-methylene-carbocyclic adenosine against wild-type and drug-resistant hepatitis B virus mutants2011
- Author(s)
  Jianing Wang, Masaya Sugiyama, 他11名
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 21 Pages: 6328-6331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors2011
- Author(s)
  Kurosaki M, Sakamoto N, Nakagawa M, Watanabe M, et al.
- Journal Title
  
  J Hepatol
  
  Volume: 54 Issue: 3 Pages: 439-448
- DOI
  10.1016/j.jhep.2010.07.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21390227, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590836, KAKENHI-PROJECT-21590837, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22790633, KAKENHI-PROJECT-23390117
[Journal Article] PEG-IFN& RBV併用療法の治療効果に寄与するヒト遺伝子多型2011
- Author(s)
  杉山真也, 溝上雅史
- Journal Title
  
  肝・胆・膵
  
  Volume: 61 Pages: 68-75
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] Host sphingolipid biosynthesis is a promising therapeutic target for the inhibition of hepatitis B virus replication.2011
- Author(s)
  Tatematsu K, Tanaka Y, Sugiyama M, Sudoh M, Mizokami M.
- Journal Title
  
  J Med Virol
  
  Volume: 83(4) Pages: 587-93
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.2011
- Author(s)
  Tanaka Y, Kurosaki M, Nishida N, Sugiyama M, Matsuura K, Sakamoto N, Enomoto N, Yatsuhashi H, Nishiguchi S, Hino K, Hige S, Itoh Y, Tanaka E, Mochida S, Honda M, Hiasa Y, Koike A, Sugauchi F, Kaneko S, Izumi N, Tokunaga K, Mizokami M
- Journal Title
  
  Hum Mol Genet
  
  Volume: 20(17) Pages: 3507-16
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Novel findings for the development of drug therapy for various liver diseases: Genetic variation in IL-28B is associated with response to the therapy for chronic hepatitis C.2011
- Author(s)
  Sugiyama M, Tanaka Y, Nakanishi M, Mizokami M
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 115(3) Pages: 263-9
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Genome-wide association study on and the clinical application to chronic hepatitis C2011
- Author(s)
  Sugiyama M, Mizokami M
- Journal Title
  
  Uirusu
  
  Volume: 61 Pages: 15-24
- NAID
  10029357046
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] Genetic Variation of the IL-28B promoter affecting gene expression2011
- Author(s)
  Masaya Sugiyama, 他4名
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C2011
- Author(s)
  Yasuhito Tanaka, Masaya Sugiyama, 他20名
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 20 Pages: 3507-3516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890255
[Journal Article] Hepatitis B virus genotype and the mutation related to clinical outcome2011
- Author(s)
  Sugiyama M, Mizokami M
- Journal Title
  
  Nihon Rinsho
  
  Volume: 69 Pages: 350-355
- NAID
  40018838496
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] ゲノミクスの手法に基づく HCV 感染者の IFN 治療効果の研究2011
- Author(s)
  杉山真也, 溝上雅史
- Journal Title
  
  ウイルス
  
  Volume: 61 (1) Pages: 15-24
- NAID
  10029357046
- Data Source
  KAKENHI-PROJECT-23390117
[Journal Article] Genetic variation of the IL-28B promoter affecting gene expression2011
- Author(s)
  Sugiyama M, Tanaka Y, Wakita T, Nakanishi M, Mizokami M
- Journal Title
  
  PLoS One
  
  Volume: 6(10) Issue: 10 Pages: e26620-e26620
- DOI
  10.1371/journal.pone.0026620
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22118003, KAKENHI-PROJECT-23240124, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23659407
[Patent] インターフェロン治療効果予測方法2013
- Inventor(s)
  溝上雅史、杉山真也、村田一素、木村達治、内藤成子
- Industrial Property Rights Holder
  溝上雅史、杉山真也、村田一素、木村達治、内藤成子
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-01
- Acquisition Date
  2013-11-01
- Data Source
  KAKENHI-PROJECT-23390117
[Patent] インターフェロン治療効果予測方法2013
- Inventor(s)
  溝上雅史, 杉山真也, 村田一素, 木村達治, 内藤成子
- Industrial Property Rights Holder
  溝上雅史, 杉山真也, 村田一素, 木村達治, 内藤成子
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-01
- Data Source
  KAKENHI-PROJECT-23390117
[Patent] B型肝炎ウイルス群を検出し、遺伝子多様性を評価するためのオリゴヌクレオチドのセット、並びにそれを用いた方法2011
- Inventor(s)
  溝上雅史、杉山真也、新井理、田村卓郎
- Industrial Property Rights Holder
  国立国際医療研究センター,ビッツ株式会社
- Filing Date
  2011-12-19
- Overseas
- Data Source
  KAKENHI-PROJECT-23890255
[Patent] IL-28Bの分析方法2011
- Inventor(s)
  溝上雅史、杉山真也、木村達治
- Industrial Property Rights Holder
  国立国際医療研究センター、特殊免疫研究所
- Industrial Property Number
  2011-287603
- Filing Date
  2011-12-28
- Data Source
  KAKENHI-PROJECT-23890255
[Patent] B型肝炎ウイルス群を検出し、遺伝子多様性を評価するためのオリゴヌクレオチドのセット、並びにそれを用いた方法2011
- Inventor(s)
  溝上雅史、杉山真也、新井理、田村卓郎
- Industrial Property Rights Holder
  国立国際医療研究センター、ビッツ株式会社
- Filing Date
  2011-12-19
- Overseas
- Data Source
  KAKENHI-PROJECT-23390117
[Patent] IL-28Bの分析方法2011
- Inventor(s)
  溝上雅史、杉山真也、木村達治
- Industrial Property Rights Holder
  国立国際医療研究センター、特殊免疫研究所
- Industrial Property Number
  2011-287603
- Filing Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-23390117
[Patent] B型肝炎ウイルス群を検出し、遺伝子多様性を評価するためのオリゴヌクレオチドのセット、並びにそれを用いた方法2011
- Inventor(s)
  溝上雅史、杉山真也、新井理、田村卓郎
- Industrial Property Rights Holder
  国立国際医療研究センター、ビッツ株式会社
- Filing Date
  2011-12-19
- Overseas
- Data Source
  KAKENHI-PROJECT-23890255
[Patent] C型肝炎患者の経過予測方法2011
- Inventor(s)
  溝上雅史、杉山真也
- Industrial Property Rights Holder
  国立国際医療研究センター
- Industrial Property Number
  2011-211647
- Filing Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-23890255
[Patent] C型肝炎患者の経過予測方法2011
- Inventor(s)
  溝上雅史、杉山真也
- Industrial Property Rights Holder
  国立国際医療研究センター
- Industrial Property Number
  2011-211647
- Filing Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] Tumor infiltrating immune cells in hepatocellular carcinoma differs according to the viral status2024
- Author(s)
  Kokudo T, Sugiyama M, Takemura N, Yoshizaki Y, Mihara F, Inagaki F, Kokudo N.
- Organizer
  APASL Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06739
[Presentation] シングルセル解析を用いた、B型肝炎ウイルス感染と病態に関連するマイクロRNAの同定とその機能解析2022
- Author(s)
  杉山真也、下遠野邦忠、溝上雅史
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K08346
[Presentation] B型肝炎ウイルスの感染初期過程に関連するヒト遺伝子の探索とその機能解析2020
- Author(s)
  杉山真也、溝上雅史
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08346
[Presentation] Influence of Gut microbiome on liver fibrosis in chimeric mice with human hepatocytes persistently infected with hepatitis B virus2019
- Author(s)
  Masaya Sugiyama
- Organizer
  France-Japan Meeting on HIV and Hepatitis in Paris
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18397
[Presentation] Integrated analyses of both human and HBV genome to predict HCC development2019
- Author(s)
  Masaya Sugiyama, Nishida Nao, Katsushi Tokunaga, Mizokami Masashi
- Organizer
  EASL Liver Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18397
[Presentation] Phylodynamic analyses of hepatitis b virus genotype a in japan2019
- Author(s)
  Kunikazu Hoshino, Masaya Sugiyama and Masashi Mizokami
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18397
[Presentation] Host factors associated with HBV related HCC in Asian populations2019
- Author(s)
  Nao Nishida, Masaya Sugiyama, Hiromi Sawai, Yong Poovorawan, Katsushi Tokunaga, Masashi Mizokami
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18397
[Presentation] Gut microbes mediate liver fibrosis in chimeric mice with human hepatocytes persistently infected with hepatitis B virus2018
- Author(s)
  Masaya Sugiyama, Tatsuya Kanto, and Masashi Mizokami
- Organizer
  THE EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18397
[Presentation] B型肝炎ウイルス感染キメラマウスモデルでの肝線維化進展における腸内細菌叢の影響とその解析2018
- Author(s)
  杉山真也、考藤達哉、溝上雅史
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17K18397
[Presentation] Liver Fibrosis Induced By Gut Microbes in Chimeric Mice Model with Human Hepatocytes Perssistently infected with hepatitis B Virus.2018
- Author(s)
  Masaya Sugiyama,Tatsuya Kanto,Masashi Mizokami
- Organizer
  The Liver Meeting 2018（AASLD）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18397
[Presentation] B型肝炎ウイルス感染キメラマウスモデルでの肝線維化進展における腸内細菌叢の影響とその解析2018
- Author(s)
  杉山真也、考藤達哉、溝上雅史
- Organizer
  日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17K18397
[Presentation] Impact of toll-like receptor 4 signaling on liver fibrosis in uPA/SCID mice with human hepatocytes persistently infected with hepatitis B virus2015
- Author(s)
  Masaya Sugiyama, Tatsuya Kanto, Masaaki Korenaga, Kazumoto Murata, Naohiko Masaki, and Masashi Mizokami
- Organizer
  The Liver Meeting 2015: The 66th Annual Meeting of AASLD
- Place of Presentation
  San Francisco
- Year and Date
  2015-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] Effect of toll-like receptor 4 signaling on liver fibrosis in uPA/SCID mice with human hepatocytes persistently infected with hepatitis B virus2015
- Author(s)
  Masaya Sugiyama, Tatsuya Kanto, and Masashi Mizokami
- Organizer
  2015 International Meeting on Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] TLR4 signaling mediate liver fibrosis in chimeric mice persistently infected with HBV2015
- Author(s)
  Masaya Sugiyama, Tatsuya Kanto, and Masashi Mizokami
- Organizer
  The 63rd Annual Meeting of The Japanese Society for Virology
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] Incidence of HBV infection in MSM cohort in Ulaanbaatar and new therapies for hepatitis B and C.2014
- Author(s)
  Masaya Sugiyama
- Organizer
  Japan-Mongolia Collaborative Study for HIV and Hepatitis in MSM in Mongolia.
- Place of Presentation
  Ulaanbaatar
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] 宿主因子を標的とした新規抗B型肝炎ウイルス製剤の開発と作用機序の解析2014
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオオタニ赤坂
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] Clinical Significance of Host Factors in Viral Hepatitis2014
- Author(s)
  Masashi Mizokami, Nao Nishida, and Masaya Sugiyama
- Organizer
  The 2nd International Symposium of Catholic University Liver Research Center Symposium
- Place of Presentation
  Korea
- Year and Date
  2014-07-26
- Invited
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] Association of sphingolipid biosynthesis pathway as a novel therapeutic target for HBV replication.2014
- Author(s)
  Masaya Sugiyama, Yasuhito Tanaka, Makoto Nakanishi, Masayuki Sudoh, and Masashi Mizokami.
- Organizer
  2014 International Meeting on Molecular Biology of Hepatitis B Viruses.
- Place of Presentation
  Los Angels
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] Number of peripheral BDCA4+dendritic cells determines the response to pegylated interferon/ribavirin therapy in chronic hepatitis C patients2013
- Author(s)
  Murata K, Sugiyama M, Kimura T, Takeda T, Yoshio S, Aoki Y, Nishida N, Yamagiwa Y, Korenaga M, Imamura M, Kanto T, Masaki N, Mizokami M
- Organizer
  The 64th annual meeting of the American association for the study of liver diseases
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] Clinical and virological analysis on Hepatitis B virus genotype D2013
- Author(s)
  Masaya Sugiyama, Yasuhito Tanaka, and Masashi Mizokami
- Organizer
  Japan-Taiwan Research Symposium on Hepatitis B.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] Polymorphisms consisting of (TA)n dinucleotide repeat near IL28B gene could improve the predictive value for HCV spontaneous clearance with IL28B SNPs2013
- Author(s)
  Sugiyama M, Hiramine S, Furusho N, Ido A, Tsubouchi H, Watanabe H, Ueno Y, Korenaga M, Murata K,, Masaki N, Mizokami M
- Organizer
  The 64th annual meeting of the American association for the study of liver diseases
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] Pre-treatment levels of serum IFN-3 more accurately predict sustained virological response by pegylated interferon/ribavirin therapy than IL28B genotyping in chronic hepatitis C patients2013
- Author(s)
  Aoki Y, Murata K,, Sugiyama M, Kimura T, Takeda T, Yoshio S, Yamagiwa Y, Korenaga M, Imamura M, Kanto T, Masaki N, Mizokami M
- Organizer
  The 64th annual meeting of the American association for the study of liver diseases
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] B型肝炎ウイルス複製に関連する脂質分子の同定とその効果2013
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] Prediction improvement on the effect of interferon-based therapy and spontaneous clearance of hepatitis C using rs72258881 near IL-28B following rs80999172013
- Author(s)
  Masaya Sugiyama, Akio Ido, Hirohito Tsubouchi, Hisayoshi Watanabe, Yoshiyuki Ueno, Kazumoto Murata, Masaaki Korenaga, and Masashi Mizokami
- Organizer
  The International Liver Congress 2013: 48th Annual Meeting of EASL
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] Human BDCA3+DC contribute to the induction of intrahepatic ISGs as a potent IFN- producer in HCV infection2013
- Author(s)
  Yoshio S, Kanto T, Matsubara T, Sugiyama M, Murata K,, Fukuhara T, Matsuura Y, Mizokami M, Hayashi N, Takehara T
- Organizer
  The 64th annual meeting of the American association for the study of liver diseases
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] Human BDCA3+dendritic cells as a potent interferon- producer and an enhancer of helper T cell and natural killer cell responsive to hepatitis C virus2013
- Author(s)
  Yoshio S, Kanto T, Matsubara T, Sugiyama M, Murata K,, Mizokami M, Hayashi N, Takehara T
- Organizer
  The 64th annual meeting of the American association for the study of liver diseases
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] Polymorphisms consisting of (TA)n dinucleotide repeat near IL28B gene could improve the predictive value for HCV spontaneous clearance with IL28B SNPs.2013
- Author(s)
  Masaya Sugiyama, Satoshi Hiramine, Norihiro Furusyo, Akio Ido, Hirohito Tsubouchi, Hisayoshi Watanabe, Yoshiyuki Ueno, Masaaki Korenaga, Kazumoto Murata, Naohiko Masaki, Jun Hayashi, and Masashi Mizokami
- Organizer
  The 64th Annual Meeting of the AASLD
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-25860574
[Presentation] Risk factors for long-term persistence of serum hepatitis B surface antigen following acute hepatitis B virus infection in Japanese adults.2013
- Author(s)
  Ito K, Yotsuyanagi H, Yatsuhashi H, Krino Y, Takikawa Y, Saito T, Arase Y, Imazeki F, Kurosaki M, Umemura T, Ichida T, Toyoda H, Yoneda M, Mita E, Yamamoto K, Michitaka K, Meshiro T, Tanuma J, Tanaka Y, Sugiyama M, Murata K, Masaki N, Mizokami M
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24591002
[Presentation] Significant roles of IFN-3 with reciprocal levels in serum and ex vivo stimulated PBMC in chronic hepatitis C2013
- Author(s)
  Aoki Y, Murata K,, Sugiyama M, Kimura T, Takeda T, Yoshio S, Nishida N, Yamagiwa Y, Korenaga M, Imamura M, Kanto T, Masaki N, Jong-Hon Kang, Mizokami M
- Organizer
  The 64th annual meeting of the American association for the study of liver diseases
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] スフィンゴ脂質合成経路の阻害によるHBV複製の抑制2012
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  肝炎ウイルス研究シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] Different Amount of IFN-λ3 Determines the Outcome of Peg-IFN/RBV Therapy in HCV Patients.2012
- Author(s)
  Murata K, Sugiyama M, Kimura T, Yoshio S, Kanto T, Kirikae I, Aoki Y, Hiramine S, Matsui T, Korenaga M, Imamura M, Masaki N, Mizokami M.
- Organizer
  The 10th JSH Single Topic Conference
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] 新規スフィンゴ脂質合成経路阻害剤によるHBV増殖抑制効果2012
- Author(s)
  杉山真也
- Organizer
  Hepatology Meeting in Japan 2012
- Place of Presentation
  椿山荘
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] No infectivity of HBV DNA and HBsAb double-positive sera in uPA/SCID chimeric mouse2012
- Author(s)
  Masaya Sugiyama, Miki Yoshida, Yuji Hoshi, Yasumi Furui, Shigeharu Uchida, Masashi Mizokami
- Organizer
  sian Pacific Association for the Study of the Liver
- Place of Presentation
  Taipei, Taiwan(Poster PP10-010)
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] スフィンゴ脂質合成経路の阻害によるHBV複製の抑制2012
- Author(s)
  」杉山真也、田中靖人、溝上雅史
- Organizer
  肝炎ウイルス研究シンポジウムS4
- Place of Presentation
  東京
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] 宿主・ウイルスゲノム解析によるC型肝炎の病態解明にむけて"Host and viral genome analyses on hepatitis C"2012
- Author(s)
  杉山真也
- Organizer
  ワークショップB1 国立遺伝学研究所研究会 NIG Workshop
- Place of Presentation
  国立遺伝学研究所三島
- Year and Date
  2012-03-12
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] C型肝炎治療の最前線 IL28B遺伝子多型による治療効果予測不一致に寄与する宿主因子の検討.2012
- Author(s)
  村田一素, 杉山真也, 溝上雅史.
- Organizer
  第16回日本肝臓学会大会
- Place of Presentation
  神戸
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] Ultrasensitive assay for genotyping of hepatitis B virus by use of an automated DNA extraction instrument.2012
- Author(s)
  Kirikae I, Ito K, Mukaide M, Sugiyama M, Murata K, Masaki N, Mizokami M.
- Organizer
  APASL2012 : 22nd conference of the Asian Pacific association for the study of the liver
- Place of Presentation
  Taipei
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] IL28B特異的測定系の開発と臨床的意義の検討2012
- Author(s)
  杉山真也,村田一素,溝上雅史
- Organizer
  シンポジウムS1-1 第77階日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  神戸商工会議所神戸
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] Genetic variation in IL-28B promoter region consisting of TA dinucleotide repeat could improve the prediction of chronic hepatitis C and spontaneous clearance with rs8099917 genotyping.2012
- Author(s)
  Masaya Sugiyama, Akio Ido, Hirohito Tsubouchi, Hisayoshi Watanabe, Yoshiyuki Ueno, Masashi Mizokami
- Organizer
  American Association for the Study of Liver Diseases
- Place of Presentation
  Boston
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] Core promoter mutations specific for hepatitis B virus genotype D1 regulating viral replication2012
- Author(s)
  Masaya Sugiyama, Sachiko Sato, Yasuhito Tanaka, Kiyoaki Ito, Kazumoto Murata, Naohiko Masaki, and Masashi Mizokami
- Organizer
  Asian Pacific Association for the Study of the Liver
- Place of Presentation
  Taipei, Taiwan(Poster PP10-017)
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] 最新の遺伝子研究からみた肝臓病の現状と個別化医療への展望C型慢性肝炎と自然治癒に関連する第二遺伝要因の探索とその応用.2012
- Author(s)
  杉山真也, 平峯智, 西田奈央, 伊藤清顕, 村田―素, 正木尚彦, 宇都浩文, 井戸章雄, 坪内博仁, 溝上雅史.
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] C型慢性肝炎と自然治癒に関連する第二遺伝要因の探索とその応用2012
- Author(s)
  杉山真也、平峯智、西田奈央、伊藤清顕、村田一素、正木尚彦、井戸章雄、坪内博仁、溝上雅史
- Organizer
  ワークショップWS25-3 第48回日本肝臓学会総会
- Place of Presentation
  ポルテ金沢金沢
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] IL-28B周囲にあるSNPsの機能解析とその意義2012
- Author(s)
  杉山真也
- Organizer
  第4回東葛・城東肝疾患研究会
- Place of Presentation
  船橋グランドホテル
- Year and Date
  2012-07-25
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] IL28B特異的測定系の開発と臨床的意義の検討2012
- Author(s)
  杉山真也, 村田一素, 溝上雅史
- Organizer
  第77階日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  神戸商工会議所
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] Genetic variation in IL-28B promoter region consisting of TA dinucleotide repeat could improve the prediction of chronic hepatitis C and spontaneous clearance with rs8099917 genotyping.2012
- Author(s)
  」Masaya Sugiyama, Akio Ido, Hirohito Tsubouchi, Hisayoshi Watanabe, Yoshiyuki Ueno, and Masashi Mizokami
- Organizer
  American Association for the Study of Liver Diseases
- Place of Presentation
  Boston(Poster P-1765)
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] 宿主・ウイルスゲノム解析によるC型肝炎の病態解明にむけて"Host and viral genome analyses On hepatitis C"2012
- Author(s)
  杉山真也
- Organizer
  国立遺伝学研究所研究会NIG Workshop
- Place of Presentation
  国立遺伝学研究所
- Year and Date
  2012-03-12
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] 活性酸素種を中心としたB型肝炎ウイルスの病態進展に関わる分子機序の解析2012
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  シンポジウムS4 Liver forum in Kyoto第14回学術集会
- Place of Presentation
  京都
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] The influence of specific mutations observed in core promoter region of HBV genotype D1 on viral replication.2012
- Author(s)
  Masaya Sugiyama, Yasuhito Tanaka, Makoto Nakanishi, Masashi Mizokami
- Organizer
  International Meeting on Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Oxford
- Year and Date
  2012-09-25
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] C型肝炎基礎Toll-like receptor 7 agonist刺激による末梢血リンパ球IFN-λ3誘導とその臨床的意義.2012
- Author(s)
  村田一素, 杉山真也, 溝上雅史.
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] Prospective Multi-center Cohort Study for the Predictive Efficacy of IL28B and ITPA SNPs in Patients with Chronic Hepatitis C Treated by Peginterferon and Ribavirin Therapy.2012
- Author(s)
  Masaki N, Sugiyama M, Tanaka Y, Shimada N, Nakamuta M, Izumi N, Watanabe S, Tsubota A, Mizokami M.
- Organizer
  The 10th JSH Single Topic Conference
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] The influence of specific mutations observed in core promoter region of HBV genotype D1 on viral replication.2012
- Author(s)
  Masaya Sugiyama, Yasuhito Tanaka, Makoto Nakanishi and Masashi Mizokami
- Organizer
  2012 International Meeting on Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Oxford, England(Poster P-109)
- Year and Date
  2012-09-25
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] Risk factors for long-term persistance of serum hbsag following accute heaptitis B virus infection in Japan.2012
- Author(s)
  Ito K, Sugiyama M, Murata K, Masaki N, Mizokami M
- Organizer
  APASL2012 : 22nd conference of the Asian Pacific association for the study of the liver
- Place of Presentation
  Taipei
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] スフィンゴ脂質合成経路の阻害によるHBV複製の抑制2012
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  肝炎ウイルス研究シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] C型慢性肝炎における臨床背景の違いと治療法選択の現状と展開C型慢性肝炎に対するペグインターフェロン・リハビリン併用療法における個別化医療多施設共同前向き研究からの考察.2012
- Author(s)
  正木尚彦, 杉山真也, 田中睛人, 伊藤清顕, 村田一素, 青木孝彦, 斉藤紘昭, 松井哲平, 今村雅俊, 溝上雅史.
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] C型慢性肝炎と自然治癒に関連する第二遺伝要因の探索とその応用2012
- Author(s)
  杉山真也、平峯智、西田奈央、伊藤清顕、村田一素、正木尚彦、井戸章雄、坪内博仁、溝上雅史
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  ポルテ金沢
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] Influence of genetic variation in IL-28B promoter on the gene expression levels2011
- Author(s)
  Masaya Sugiyama, Yasuhito Tanaka, Makoto Nakanishi, and Masashi Mizokami
- Organizer
  International Union of Microbiological Societies Congresses 2011
- Place of Presentation
  Sapporo(Poster VI-PO18-6)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] キメラマウスでのB型肝炎の病態進展に関わる分子機構の検討2011
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] キメラマウスでのB型肝炎の病態進展に関わる分子機構の検討2011
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] ホストのスフィンゴ脂質合成系を標的とした抗HBV薬のキメラマウスにおける検討2011
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  パネルディスカッションPD4-3 第19回日本消化器関連学会週間
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] Polymorphism of IL-28B promoter region could improve the prediction value of response to CHC treatment following rs8099917 genotyping.2011
- Author(s)
  Masaya Sugiyama, Yasuhito Tanaka, Masashi Mizokami
- Organizer
  American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco(Poster P-407)
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] IL-28B遺伝子周囲に存在するSNPsの機能解析と臨床的意義2011
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  シンポジウムS2-13 第19回日本消化器関連学会週間
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] ホストのスフィンゴ脂質合成系を標的とした抗HBV薬のキメラマウスにおける検討2011
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  第19回日本消化器関連学会週間
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] IL-28B遺伝子周囲に存在するSNPsの機能解析と臨床的意義2011
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  第19回日本消化器関連学会週間
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] The impact of core promoter mutations specific for hepatitis B virus genotype D1 on viral replication2011
- Author(s)
  Masaya Sugiyama, Yasuhito Tanaka, Makoto Nakanishi, and Masashi Mizokami
- Organizer
  Asian Pacific Digestive Week 2011
- Place of Presentation
  Singapore(Poster 848)
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] キメラマウスでのB型肝炎の病態進展に関わる分子機構の検討2011
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  シンポジウムSY-1-11 第47回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-23890255
[Presentation] ホストのスフィンゴ脂質合成系を標的とした抗HBV薬のキメラマウスにおける検討2011
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  第19回日本消化器関連学会週間
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-23390117
[Presentation] IL-28B遺伝子周囲に存在するSNPsの機能解析と臨床的意義2011
- Author(s)
  杉山真也、田中靖人、溝上雅史
- Organizer
  第19回日本消化器関連学会週間
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-23890255

1. ITO Kiyoaki (50551420)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. MIZOAKMI Masashi (40166038)

# of Collaborated Projects: 2 results

# of Collaborated Products: 43 results
3. MURATA Kazumoto (40345971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
4. SUZUKI Yoshiyuki (70353430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MASAKI NAOHIKO (40219316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 市村宏 (10264756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田中靖人 (90336694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 村上周子 (50454848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 関谷高史 (80519207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 國土貴嗣 (40802921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. Pradeep Shrestha

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Yong Poovorawan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Nawarat Posuwan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Mostafa Mohamed Ragheb

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Pham Van Thuc

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Nguyen Hung Cuong

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KAMO Ken-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 滝川修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 奥野海良人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 中西真

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 石井孝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 徳永勝士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 渡辺守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 坂本直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 中川美奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 坪田昭人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 田中純子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 田中詩織

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUGIYAMA MASAYA 杉山 真也

Sugiyama Masaya 杉山 真也

SUGIYAMA Masasya 杉山 真也

Research Projects

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Co-Researchers

B型肝炎ウイルスの感染侵入に関わる分子機序の解明Principal Investigator

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ナイーブT細胞の不均一性に着目した組織特異的免疫応答の解明および免疫制御法の開発

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Elucidation of pathology and development of a new treatment for hepatocellular carcinoma through single-cell analysis

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Research for analysis of receptor gene used by hepatitis B virusPrincipal Investigator

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Research on effect of macrophage on liver fibrosis in a mouse model of hepatitis BPrincipal Investigator

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Survey on the measures against viral hepatitis in developing countries of Asia and Africa

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Molecular basis of liver fibrosis progression in humanized mouse model infected with HBVPrincipal Investigator

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Development of the method for the prevention of the chronicity of hepatitis B virus infection using two types of next generation sequencer

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Response and specific function of IFN-lambda3 against infectious diseases

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Analyses on the progression of liver fibrosis induced by hepatitis B virus infectionPrincipal Investigator

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Investigation the mechanisms of chronicity from acute hepatitis B using a next generation sequencer

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[Book] ゲノムワイド関連解析とその応用2011

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Data Source

[Journal Article] Prolyl Isomerase Pin1 Regulates the Stability of Hepatitis B Virus Core Protein.2020

Author(s)

Journal Title

SUGIYAMA MASAYA 杉山真也

Sugiyama Masaya 杉山真也

SUGIYAMA Masasya 杉山真也