Shirai Tsuyoshi 白井剛志

… Alternative Names

白井剛志シライツヨシ

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Researcher Number	20646997
Other IDs
Affiliation (Current)	2025: 東北大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 東北大学, 大学病院, 講師 2019 – 2022: 東北大学, 大学病院, 助教 2016 – 2018: 東北大学, 医学系研究科, 助教 2013: 東北大学, 医学(系)研究科(研究院), その他
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology / Neurology Except Principal Investigator Laboratory medicine
Keywords	Principal Investigator 自己抗体 / 高安動脈炎 / プロテインC受容体 / 潰瘍性大腸炎 / 膠原病 / プロテインC / EPCR / 病態形成 / 炎症性疾患 / ピルビン酸キナーゼM2 … More / 解糖系 / マクロファージ / PKM2 / 細胞内代謝 / 循環器 / 免疫学 / 内科 … More Except Principal Investigator B細胞レパトア解析 / 抗CCP抗体 / 生物学的製剤 / BCRレパトア / ＢＣＲレパトア / TCRレパトア / アバタセプト / レパトア解析 / 関節リウマチ Less

高安動脈炎と潰瘍性大腸炎に共通する抗EPCR抗体を軸とした病態解明と臨床応用の検討Principal Investigator
- Principal Investigator
  
  白井剛志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tohoku University
Novel syndrome based on the common pathophysiology among Takayasu arteritis and ulcerative colitisPrincipal Investigator
- Principal Investigator
  
  Shirai Tsuyoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tohoku University
Regulation of inflammatory diseases by pyruvate kinase M2Principal Investigator
- Principal Investigator
  
  Shirai Tsuyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tohoku University
Development of a new rheumatoid arthritis monitoring method by analysis of anti-CCP antibody-producing B cell repertoire
- Principal Investigator
  
  ISHII Tomonori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tohoku University
Novel autoantibodies in Takayasu arteritisPrincipal Investigator
- Principal Investigator
  
  Shirai Tsuyoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Tohoku University
脳症を呈する膠原病患者における抗EphB2抗体の臨床的・病原的意義の解明Principal Investigator
- Principal Investigator
  
  白井剛志
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 Other

All Journal Article Presentation Book Patent Other

[Book] 1ページでわかる内科疾患の診療ノート “あたりまえ”のなかにある大事な視点(Vol.129 No.4)2022年4月増大号2022
- Author(s)
  白井剛志
- Total Pages
  706
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21K08469
[Book] 血管炎の診療update2022
- Author(s)
  白井剛志
- Total Pages
  1315
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Impact of subcutaneous belimumab on disease activity, patient satisfaction, and metabolic profile in long-lasting systemic lupus erythematosus2024
- Author(s)
  Yamato Maya、Shirai Tsuyoshi、Ishii Yusho、Sato Hiroko、Ishii Tomonori、Fujii Hiroshi
- Journal Title
  
  Clinical Rheumatology
  
  Volume: 43 Issue: 3 Pages: 1023-1035
- DOI
  10.1007/s10067-024-06904-9
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Comment on: A case of vanishing bile duct syndrome during treatment of microscopic polyangiitis with avacopan2023
- Author(s)
  Shirota Sae、Shirai Tsuyoshi、Mori Kentaro、Inoue Jun、Sato Hiroko、Ishii Tomonori、Fujii Hiroshi
- Journal Title
  
  Rheumatology
  
  Volume: 63 Issue: 4 Pages: e149-e150
- DOI
  10.1093/rheumatology/kead561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] First reported case of pulmonary arteritis in patients with relapsing polychondritis2023
- Author(s)
  Yamato Maya、Shirai Tsuyoshi、Sato Hiroko、Ishii Tomonori、Fujii Hiroshi
- Journal Title
  
  Rheumatology
  
  Volume: 63 Issue: 1 Pages: e9-e11
- DOI
  10.1093/rheumatology/kead300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Establishing clinical remission criteria for?giant cell arteritis: Results of?a Delphi exercise carried out by an expert panel of?the Japan Research Committee of?the Ministry of?Health, Labour, and?Welfare for?Intractable?Vasculitis2023
- Author(s)
  Sugihara Takahiko、Yoshifuji Hajime、Uchida Haruhito A、Maejima Yasuhiro、Watanabe Yoshiko、Tanemoto Kazuo、Umezawa Natsuka、Manabe Yusuke、Ishizaki Jun、Shirai Tsuyoshi、Nagafuchi Hiroko、Hasegawa Hitoshi、Niiro Hiroaki、Ishii Tomonori、Nakaoka Yoshikazu、Harigai Masayoshi
- Journal Title
  
  Modern Rheumatology
  
  Volume: 34 Issue: 3 Pages: 568-575
- DOI
  10.1093/mr/road046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08469, KAKENHI-PROJECT-23K27605
[Journal Article] Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet+B cells in systemic lupus erythematosus.2023
- Author(s)
  Yasaka K, Yamazaki T, Sato H, Shirai T, Cho M, Ishida K, Ito K, Tanaka T, Ogasawara K, Harigae H, Ishii T, Fujii H.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 25 Issue: 1 Pages: 200-200
- DOI
  10.1186/s13075-023-03186-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-21K08452, KAKENHI-PROJECT-21K08469
[Journal Article] Severe Bone Marrow Aplasia Following Macrophage Activation Syndrome in Systemic Lupus Erythematosus2023
- Author(s)
  Ichimura Hirona、Ichikawa Satoshi、Ono Koya、Inokura Kyoko、Hoshi Yosuke、Shirai Tsuyoshi、Fukuhara Noriko、Yokoyama Hisayuki、Fujii Hiroshi、Harigae Hideo
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 260 Issue: 4 Pages: 301-304
- DOI
  10.1620/tjem.2023.J037
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Common dysbiosis features between patients of different social environments in Takayasu arteritis: Comments on the article by Fan et al.2023
- Author(s)
  Shirai Tsuyoshi、Watanabe Satoshi、Shinozaki Natsuko O.、Baba Kairi、Yamasaki Hiroyuki、Ishii Tomonori、Fujii Hiroshi
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: - Issue: 7 Pages: 1291-1292
- DOI
  10.1002/art.42438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Common Autoantibody among Takayasu Arteritis and Ulcerative Colitis: A Possible Pathophysiology That Includes Gut-Vessel Connection in Vascular Inflammation2023
- Author(s)
  Shirai Tsuyoshi
- Journal Title
  
  JMA Journal
  
  Volume: 6 Issue: 3 Pages: 265-273
- DOI
  10.31662/jmaj.2023-0038
- ISSN
  2433-328X, 2433-3298
- Year and Date
  2023-07-14
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Successful management of interstitial lung disease in dermatomyositis complicated by malignancy: a case-based review2023
- Author(s)
  Katakura Tokio、Shirai Tsuyoshi、Sato Hiroko、Ishii Tomonori、Fujii Hiroshi
- Journal Title
  
  Rheumatology International
  
  Volume: Sep 8 Issue: 9 Pages: 1781-1788
- DOI
  10.1007/s00296-023-05442-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Development of severe colitis in Takayasu arteritis treated with tocilizumab2022
- Author(s)
  Ishii Kae、Shirai Tsuyoshi、Kakuta Yoichi、Machiyama Tomoaki、Sato Hiroko、Ishii Tomonori、Harigae Hideo、Fujii Hiroshi
- Journal Title
  
  Clinical Rheumatology
  
  Volume: - Issue: 6 Pages: 1911-1918
- DOI
  10.1007/s10067-022-06108-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Granulomatosis with polyangiitis following Pfizer-BioNTech COVID-19 vaccination2022
- Author(s)
  Shirai Tsuyoshi、Suzuki Jun、Kuniyoshi Shimpei、Tanno Yuito、Fujii Hiroshi
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: - Issue: 1 Pages: 127-129
- DOI
  10.1093/mrcr/rxac016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Predictive factors for retention of golimumab over a median 4‐year duration in Japanese patients with rheumatoid arthritis in a real‐world setting: A retrospective study and literature review2022
- Author(s)
  Mutoh Tomoyuki、Nagai Taichi、Shirai Tsuyoshi、Okazaki Soshi、Sato Hiroko、Fujii Hiroshi
- Journal Title
  
  International Journal of Rheumatic Diseases
  
  Volume: 25 Issue: 3 Pages: 335-343
- DOI
  10.1111/1756-185x.14281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469, KAKENHI-PROJECT-20K17419
[Journal Article] Dysbiosis in Takayasu arteritis complicated with infectious endocarditis following tocilizumab administration2022
- Author(s)
  Shirai T、Sato H、Ishii T、Fujii H
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: 52 Issue: 2 Pages: 224-226
- DOI
  10.1080/03009742.2022.2124620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Sjögren’s Syndrome Presenting with Temporary Hemiplegia Mimicking Transient Ischemic Attack2022
- Author(s)
  Kamogawa Yukiko、Akita Kanae、Sato Hiroko、Shirai Tsuyoshi、Ishii Tomonori、Harigae Hideo、Fujii Hiroshi
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 258 Issue: 3 Pages: 207-211
- DOI
  10.1620/tjem.2022.J079
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Hypertrophic Pachymeningitis Development in Eosinophilic Granulomatosis with Polyangiitis at Relapse of Disease: A Case-Based Review2022
- Author(s)
  Kiyohara Machi、Shirai Tsuyoshi、Nishiyama Shuhei、Sato Hiroko、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 256 Issue: 3 Pages: 241-247
- DOI
  10.1620/tjem.256.241
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Intensive induction therapy combining tofacitinib, rituximab and plasma exchange in severe anti-melanoma differentiation-associatedprotein-5 antibody-positive dermatomyositis2022
- Author(s)
  Shirai Tsuyoshi、Machiyama Tomoaki、Sato Hiroko、Ishii Tomonori、Fujii Hiroshi
- Journal Title
  
  Clinical and Experimental Rheumatology
  
  Volume: 41 Pages: 291-300
- DOI
  10.55563/clinexprheumatol/8kulbf
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Presence of Phlebitis in Aseptic Nasal Septal Abscess Complicated with Ulcerative Colitis; Possible Association with Granulomatosis with Polyangiitis: A Case Report2022
- Author(s)
  Ishikawa Tomohiko、Suzuki Jun、Shirai Tsuyoshi、Koizumi Shotaro、Tsuchiya Yoshinori、Hishinuma Kasumi、Nakamura Yasuhiro、Katori Yukio
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 258 Issue: 1 Pages: 29-34
- DOI
  10.1620/tjem.2022.J053
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] “Coexistence of IgA nephropathy and renal artery stenosis in Takayasu arteritis: case report and literature review”2022
- Author(s)
  Ito Nono、Shirai Tsuyoshi、Toyohara Takafumi、Hashimoto Hideaki、Sato Hiroko、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  Rheumatology International
  
  Volume: Ahead of print Issue: 2 Pages: 391-398
- DOI
  10.1007/s00296-021-05066-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08245, KAKENHI-PROJECT-21K08469
[Journal Article] The feasible maintenance dose of corticosteroid in Takayasu arteritis in the era of biologic therapy2021
- Author(s)
  Shirai T、Sato H、Fujii H、Ishii T、Harigae H
- Journal Title
  
  Scandinavian Journal of Rheumatology
  
  Volume: Mar 17 Issue: 6 Pages: 1-7
- DOI
  10.1080/03009742.2021.1881155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16136
[Journal Article] Interferon α Enhances B Cell Activation Associated With FOXM1 Induction: Potential Novel Therapeutic Strategy for Targeting the Plasmablasts of Systemic Lupus Erythematosus2021
- Author(s)
  Akita Kanae、Yasaka Ken、Shirai Tsuyoshi、Ishii Tomonori、Harigae Hideo、Fujii Hiroshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 498703-498703
- DOI
  10.3389/fimmu.2020.498703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16136
[Journal Article] Distinct autoantibodies against endothelial protein C receptor in ulcerative colitis2021
- Author(s)
  Shirai Tsuyoshi、Kakuta Yoichi、Fujii Hiroshi
- Journal Title
  
  Gastroenterology
  
  Volume: Mar Issue: 5 Pages: 1-2
- DOI
  10.1053/j.gastro.2021.03.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16136, KAKENHI-PROJECT-21K08469
[Journal Article] Association of various myositis-specific autoantibodies with dermatomyositis and polymyositis triggered by pregnancy2021
- Author(s)
  Akiyama Chikaho、Shirai Tsuyoshi、Sato Hiroko、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  Rheumatology International
  
  Volume: - Issue: 7 Pages: 1271-1280
- DOI
  10.1007/s00296-021-04851-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Multi-targeted therapy for refractory eosinophilic granulomatosis with polyangiitis characterized by intracerebral hemorrhage and cardiomyopathy: a case-based review2021
- Author(s)
  Mutoh Tomoyuki、Shirai Tsuyoshi、Sato Hiroko、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  Rheumatology International
  
  Volume: - Issue: 11 Pages: 2069-2076
- DOI
  10.1007/s00296-021-04950-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469, KAKENHI-PROJECT-20K17419
[Journal Article] Novel Diagnostic Autoantibodies Against Endothelial Protein C Receptor in Patients With Ulcerative Colitis2021
- Author(s)
  Kakuta Yoichi、Shirai Tsuyoshi、McGovern Dermot P.B.、Braun Jonathan、Fujii Hiroshi、Masamune Atsushi
- Journal Title
  
  Clinical Gastroenterology and Hepatology
  
  Volume: - Issue: 3 Pages: 844-846
- DOI
  10.1016/j.cgh.2021.12.035
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Establishing clinical remission criteria and the framework of a treat-to-target?algorithm for Takayasu arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour and Welfare for intractable vasculitis2021
- Author(s)
  Sugihara Takahiko、Nakaoka Yoshikazu、Uchida Haruhito A、Yoshifuji Hajime、Maejima Yasuhiro、Watanabe Yoshiko、Amiya Eisuke、Tanemoto Kazuo、Miyata Tetsuro、Umezawa Natsuka、Manabe Yusuke、Ishizaki Jun、Shirai Tsuyoshi、Nagafuchi Hiroko、
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 5 Pages: 930-937
- DOI
  10.1093/mr/roab081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469, KAKENHI-PROJECT-21K07853
[Journal Article] Cyclophosphamide-associated enteritis presenting with severe protein-losing enteropathy in granulomatosis with polyangiitis: A case report2021
- Author(s)
  Sato Hiroko、Shirai Tsuyoshi、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 27 Issue: 20 Pages: 2657-2663
- DOI
  10.3748/wjg.v27.i20.2657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08469
[Journal Article] Migratory Aortitis Associated with Granulocyte-colony-stimulating Factor2020
- Author(s)
  Shirai Tsuyoshi、Komatsu Hiroka、Sato Hiroko、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 12 Pages: 1559-1563
- DOI
  10.2169/internalmedicine.4331-19
- NAID
  130007854988
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-06-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08401, KAKENHI-PROJECT-18K16136
[Journal Article] Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.2020
- Author(s)
  Mutoh T, Shirai T, Ishii T, Shirota Y, Fujishima F, Takahashi F, Kakuta Y, Kanazawa Y, Masamune A, Saiki Y, Harigae H, Fujii H.
- Journal Title
  
  Nat Commun.
  
  Volume: 11(1) Issue: 1 Pages: 1-13
- DOI
  10.1038/s41467-020-15088-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-18K08401, KAKENHI-PROJECT-18K16136
[Journal Article] Extranasal extranodal NK/T-cell lymphoma associated with systemic lupus erythematosus2020
- Author(s)
  Ichikawa Satoshi、Fukuhara Noriko、Shirai Tsuyoshi、Ishii Tomonori、Ichinohasama Ryo、Harigae Hideo
- Journal Title
  
  International Journal of Hematology
  
  Volume: 112 Issue: 4 Pages: 592-596
- DOI
  10.1007/s12185-020-02914-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16136
[Journal Article] Comment on: Aortarctia: a rare manifestation of relapsing polychondrits2020
- Author(s)
  Shirai Tsuyoshi、Murakami Koji、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  Rheumatology
  
  Volume: 59 Issue: 7 Pages: 1784-1785
- DOI
  10.1093/rheumatology/keaa019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08401, KAKENHI-PROJECT-18K16136
[Journal Article] Rheumatoid Arthritis After Cord Blood Cell Transplantation2020
- Author(s)
  Shirai Tsuyoshi、Mori Yu、Izumiyama Takuya、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  JCR: Journal of Clinical Rheumatology
  
  Volume: Jun 12 Issue: 7 Pages: 1-2
- DOI
  10.1097/rhu.0000000000001430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16136
[Journal Article] Successful Treatment of Pulmonary Arterial Hypertension in Systemic Sclerosis with Anticentriole Antibody.2020
- Author(s)
  Ishii Y, Fujii H, Sugimura K, Shirai T, Hoshi Y, Fujita Y, Shirota Y, Ishii T, Shimokawa H, Harigae H.
- Journal Title
  
  Case Rep Rheumatol.
  
  Volume: 2020 Pages: 1-7
- DOI
  10.1155/2020/1926908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-18K08401, KAKENHI-PROJECT-18K16136
[Journal Article] Insufficient Use of Corticosteroids without Immunosuppressants Results in Higher Relapse Rates in Takayasu Arteritis2019
- Author(s)
  Mutoh Tomoyuki、Shirai Tsuyoshi、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  The Journal of Rheumatology
  
  Volume: 47 Issue: 2 Pages: 255-263
- DOI
  10.3899/jrheum.181219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16136, KAKENHI-PROJECT-17K08973
[Journal Article] Four distinct clinical phenotypes of vasculitis affecting medium-sized arteries.2019
- Author(s)
  Shirai T, Shirota Y, Fujii H, Ishii T, Harigae H.
- Journal Title
  
  Scand J Rheumatol
  
  Volume: 48 Issue: 4 Pages: 1-7
- DOI
  10.1080/03009742.2018.1551965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-18K16136, KAKENHI-PROJECT-17K08973
[Journal Article] Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis (AAV) Restricted to the Limbs2018
- Author(s)
  Ojima Y, Sawada K, Fujii H, Shirai T, Saito A, Kagaya S, Aoki S, Takeuchi Y, Ishii T, Nagasawa T.
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 9 Pages: 1301-1308
- DOI
  10.2169/internalmedicine.9848-17
- NAID
  130006730798
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-05-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-15K09515
[Journal Article] Multicenter double-blind randomized controlled trial to evaluate the effectiveness and safety of bortezomib as a treatment for refractory systemic lupus erythematosus.2018
- Author(s)
  Ishii T, Tanaka Y, Kawakami A, Saito K, Ichinose K, Fujii H, Shirota Y, Shirai T, Fujita Y, Watanabe R, Chiu SW, Yamaguchi T, Harigae H.
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 6 Pages: 1-7
- DOI
  10.1080/14397595.2018.1432331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-15K09515, KAKENHI-PROJECT-18K16136
[Journal Article] Takayasu Arteritis Coexisting with Sclerosing Osteomyelitis2018
- Author(s)
  Shirai T, Hanaoka R, Goto Y, Kojima I, Ishii Y, Hoshi Y, Fujita Y, Shirota Y, Fujii H, Ishii T, Harigae H.
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 13 Pages: 1929-1934
- DOI
  10.2169/internalmedicine.0329-17
- NAID
  130007387190
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-18K16136, KAKENHI-PROJECT-15K11287
[Journal Article] Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity.2017
- Author(s)
  Ikeda T, Fujii H, Nose M, Kamogawa Y, Shirai T, Shirota Y, Ishii T, Harigae H.
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 19（1） Issue: 1 Pages: 187-187
- DOI
  10.1186/s13075-017-1397-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-15K09515
[Journal Article] Relapsing Polychondritis Complicated by Myelodysplastic Syndrome Is Resistant to Immunosuppression: Comment on the Article by Dion et al.2017
- Author(s)
  Shirai T, Fujii H, Saito R, Nasu K, Kamogawa Y, Fukuhara N, Fujita Y, Shirota Y, Ishii T, Harigae H.
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: 69 Issue: 3 Pages: 682-683
- DOI
  10.1002/art.39969
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-26461457, KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-15K09515
[Journal Article] Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunity.2017
- Author(s)
  Watanabe R, Shirai T, Namkoong H, Zhang H, Berry GJ, Wallis BB, Schaefgen B, Harrison DG, Tremmel JA, Giacomini JC, Goronzy JJ, Weyand CM.
- Journal Title
  
  The Journal of Clinical Investigation
  
  Volume: 127(7) Issue: 7 Pages: 2725-2738
- DOI
  10.1172/jci92167
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06642
[Patent] 炎症性腸疾患の診断方法、診断プローブ及び診断キット2019
- Inventor(s)
  白井剛志, 藤井博司, 石井智徳, 張替秀郎ら
- Industrial Property Rights Holder
  白井剛志, 藤井博司, 石井智徳, 張替秀郎ら
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Acquisition Date
  2019
- Data Source
  KAKENHI-PROJECT-18K16136
[Patent] 高安動脈炎の診断方法、診断マーカー及び診断キット2018
- Inventor(s)
  白井剛志、藤井博司、石井智徳、張替秀郎
- Industrial Property Rights Holder
  白井剛志、藤井博司、石井智徳、張替秀郎
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2018
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] Novel Autoantibodies in Takayasu Arteritis Suggests Gut-vessel Connection in Vascular Inflammation2024
- Author(s)
  白井剛志
- Organizer
  日本循環器病学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08469
[Presentation] IMBALANCE IN THE TAXONOMIC COMPOSITION OF GUT MICROBIOTA IN TAKAYASU ARTERITIS2024
- Author(s)
  Shirai T et al.
- Organizer
  EULAR2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08469
[Presentation] 抗MDA5抗体陽性皮膚筋炎に対するトファシチニブ、血漿交換、リツキシマブを使用した高強度寛解導入療法の治療成績2022
- Author(s)
  白井剛志、丹野唯人、星陽介、秋田佳奈恵、町山智章、佐藤紘子、藤井博司、石井智徳
- Organizer
  第66回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-21K08469
[Presentation] ASSOCIATION OF NOVEL DIAGNOSTIC AUTOANTIBODIES AGAINST ENDOTHELIAL PROTEIN C RECEPTOR IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE2022
- Author(s)
  Yoichi Kakuta, Tsuyoshi Shirai, Soshi Okazaki, Yusuke Shimoyama, Rintaro Moroi, Masatake Kuroha, Hisashi Shiga, Yoshitaka Kinouchi, Dalin Li, Jonathan G. Braun, Dermot P.B. Mcgovern, Hiroshi Fujii, Atsushi Masamune
- Organizer
  アメリカ消化器病学会2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08469
[Presentation] 高安動脈炎における生物学的製剤の長期的有効性と継続率の検討2022
- Author(s)
  白井剛志、町山智章、佐藤紘子、藤井博司、石井智徳
- Organizer
  第66回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-21K08469
[Presentation] HIGH-INTENSITY INDUCTION THERAPY COMBINING TOFACITINIB, RITUXIMAB, AND PLASMAPHERESIS IN RAPIDLY PROGRESSIVE INTERSTITIAL LUNG DISEASE ASSOCIATED WITH ANTI-MDA5 ANTIBODY POSITIVE DERMATOMYOSITIS2022
- Author(s)
  Shirai T, Sato H, Fujii H, Ishii T
- Organizer
  ヨーロッパリウマチ学会2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08469
[Presentation] Endothelial protein C receptor and scavenger receptor class B type 1 negatively regulate endothelial activation2020
- Author(s)
  Shirai T, Mutoh T, Fujii H, Ishii T, Harigae H
- Organizer
  EULAR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] 大型血管炎におけるステロイド寛解維持量の検討2020
- Author(s)
  白井剛志, 武藤智之, 佐藤紘子, 藤井博司, 石井智徳, 張替秀郎
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] 生物学的製剤を使用した大型血管炎患者の検討2019
- Author(s)
  白井剛志, 武藤智之, 藤田洋子, 藤井博司, 石井智徳, 平林泰彦, 張替秀郎
- Organizer
  第63回日本リウマチ学会総会・学術集会ワークショップ
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] Endothelial Protein C Receptor and Scavenger Receptor Class B Type 1 Negatively Regulate Vascular Inflammation and Are Major Autoantigens in Takayasu Arteritis2019
- Author(s)
  Tomoyuki Mutoh, Tsuyoshi Shirai, Tomonori Ishii, Yuko Shirota, Hideo Harigae, Hiroshi Fujii
- Organizer
  American College of Rheumatology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] Identification of endothelial proten C receptor and scavenger receptor class B type 1 as major autoantigens in Takayasu arteritis2019
- Author(s)
  Tsuyoshi Shirai, Tomoyuki Mutoh, Tomonori Ishii, Hiroshi Fujii, Hideo Harigae
- Organizer
  EULAR2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] Optimized Protocol for Extracorporeal Shock Wave Therapy on Digital Ulcers in Systemic Sclerosis2018
- Author(s)
  Tomonori Ishii, Yasushi Kawaguchi, Osamu Ishikawa, Hiromitsu Takemori, Naruhiko Takasawa, Hitoshi Kobayashi, Yuichi Takahashi, Hidekata Yasuoka, Takao Kodera, Osamu Takai, Izaya Nakaya, Tomomasa Izumiyama, Hiroshi Fujii, Yukiko Kamogawa, Yuko Shirota, Tsuyoshi Shirai et al.
- Organizer
  American College of Rheumatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] リウマチ性疾患の合併症(感染症以外・アミロイドーシス・その他)3:その他2 膠原病性肺動脈性肺高血圧症(CTD-PAH)における予後予測因子と死因について2018
- Author(s)
  城田祐子, 星陽介, 佐藤紘子, 藤田洋子, 白井剛志, 藤井博司, 石井智徳, 張替秀郎
- Organizer
  日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-17K08973
[Presentation] Insufficient Use of Corticosteroids Results in Higher Relapse in Takayasu Arteritis2018
- Author(s)
  Tomoyuki Muto, Tsuyoshi Shirai, Hiroshi Fujii, Tomonori Ishii, Hideo Harigae
- Organizer
  American College of Rheumatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] High Prevalence of Vascular Surgery and Autoimmune Comorbidity in Takayasu Arteritis2018
- Author(s)
  Tsuyoshi Shirai, Tomoyuki Muto, Yuko Shirota, Hiroshi Fujii, Tomonori Ishii, Hideo Harigae
- Organizer
  American College of Rheumatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] 強皮症・MCTD・重複症候群1 全身性強皮症に伴う難治性皮膚潰瘍に対する低出力衝撃波療法の有効性・安全性検証試験2018
- Author(s)
  石井智徳(東北大学病院臨床研究推進センター), 川口鎮司, 石川治, 竹森弘光, 高澤徳彦, 小林仁, 安岡秀剛, 高橋裕一, 小寺隆雄, 高井修, 中屋来哉, 泉山朋政, 齋藤真一郎, 鴨川由起子, 藤田洋子, 白井剛志, 城田祐子, 藤井博司, 張替秀郎
- Organizer
  日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-17K08973
[Presentation] Autoantibodies and Clinical Outcomes in Pulmonary Arterial Hypertension Associated with Connective Tissue Diseases2018
- Author(s)
  Yuko Shirota, Tomonori Ishii, Tsuyoshi Shirai, Hiroshi Fujii, Hideo Harigae
- Organizer
  American College of Rheumatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16136
[Presentation] Four-Distinct Phenotypes of Patients with Necrotizing Arteritis of Medium and Small Artery2017
- Author(s)
  Tsuyoshi Shirai, Hiroshi Fujii, Yuko Shirota, Tomonori Ishii and Hideo Harigae
- Organizer
  2017 ACR/ARHP Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06642
[Presentation] 中小動脈を首座とする血管炎47例の臨床的検討2017
- Author(s)
  白井剛志、藤田洋子、城田祐子、藤井博司、石井智徳、張替秀郎
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16H06642
[Presentation] Four-Distinct Phenotypes of Patients with Necrotizing Arteritis of Medium and Small Artery2017
- Author(s)
  Ishii T, Kawaguchi Y, Ishikawa O, Takasawa N, Kodera T, Yasuoka H, Takahashi Y, Takai O, Nakaya I, Fujii H, Kamogawa Y, Shirota Y, Shirai T, Fujita Y, Saito S, Shimokawa H and Harigae H.
- Organizer
  2017 ACR/ARHP Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08973
[Presentation] Establishment of a Powerful Method to Identify Autoantigens Expressed on the Cell Surface2016
- Author(s)
  Tsuyoshi Shirai, Hiroshi Fujii, Tomoyuki Muto, Yuko Shirota, Yoko Fujita, Tomonori Ishii, Hideo Harigae
- Organizer
  2016 ACR Annual Meeting
- Place of Presentation
  Walter E. Washington Convention Center (USA)
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06642
[Presentation] An fffective method to identify autoantigens expressed on the cell surface: SARF2016
- Author(s)
  Tsuyoshi Shirai
- Organizer
  The 13th International Workshop on Autoantibodies and Autoimmunity
- Place of Presentation
  ウエスティン都ホテル京都（京都府京都市）
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06642
[]

1. ISHII Tomonori (10282138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. 小笠原康悦 (30323603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 藤井博司 (30531321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 城田祐子 (20455819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. TANAKA Tetsuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 豊原敬文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shirai Tsuyoshi 白井 剛志

白井 剛志 シライ ツヨシ

Research Projects

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Co-Researchers

高安動脈炎と潰瘍性大腸炎に共通する抗EPCR抗体を軸とした病態解明と臨床応用の検討Principal Investigator

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Novel syndrome based on the common pathophysiology among Takayasu arteritis and ulcerative colitisPrincipal Investigator

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Regulation of inflammatory diseases by pyruvate kinase M2Principal Investigator

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Development of a new rheumatoid arthritis monitoring method by analysis of anti-CCP antibody-producing B cell repertoire

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Novel autoantibodies in Takayasu arteritisPrincipal Investigator

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脳症を呈する膠原病患者における抗EphB2抗体の臨床的・病原的意義の解明Principal Investigator

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[Book] 1ページでわかる内科疾患の診療ノート “あたりまえ”のなかにある大事な視点(Vol.129 No.4)2022年4月増大号2022

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[Book] 血管炎の診療update2022

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[Journal Article] Impact of subcutaneous belimumab on disease activity, patient satisfaction, and metabolic profile in long-lasting systemic lupus erythematosus2024

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[Journal Article] Comment on: A case of vanishing bile duct syndrome during treatment of microscopic polyangiitis with avacopan2023

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[Journal Article] First reported case of pulmonary arteritis in patients with relapsing polychondritis2023

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[Journal Article] Establishing clinical remission criteria for?giant cell arteritis: Results of?a Delphi exercise carried out by an expert panel of?the Japan Research Committee of?the Ministry of?Health, Labour, and?Welfare for?Intractable?Vasculitis2023

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[Journal Article] Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet+B cells in systemic lupus erythematosus.2023

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[Journal Article] Severe Bone Marrow Aplasia Following Macrophage Activation Syndrome in Systemic Lupus Erythematosus2023

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Shirai Tsuyoshi 白井剛志

白井剛志シライツヨシ