fujii hiroshi 藤井博司

… Alternative Names

FUJII Hiroshi 藤井博司

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Researcher Number	30531321
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 東北大学, 医学系研究科, 教授 2020 – 2024: 東北大学, 大学病院, 准教授 2023: 東北大学, 東北大学病院, 准教授 2016 – 2021: 東北大学, 医学系研究科, 准教授 2014 – 2015: 東北大学, 医学(系)研究科(研究院), 准教授 2012 – 2013: 東北大学, 大学病院, 講師 2010 – 2011: 東北大学, 病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / 膠原病・アレルギー・感染症内科学 / Collagenous pathology/Allergology Except Principal Investigator Collagenous pathology/Allergology / Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related / Basic Section 90140:Medical technology assessment-related / Basic Section 90130:Medical systems-related / Medium-sized Section 90:Biomedical engineering and related fields / Laboratory medicine
Keywords	Principal Investigator 全身性エリテマトーデス / 形質芽細胞 / B細胞 / 自己抗体 / 膠原病 / 抗核酸抗体 / 抗DNA抗体 / 全身生エリテマトーデス / 難治性皮膚潰瘍 / 血管新生 … More / FosB / 体外衝撃波照射 / FOSB / 皮膚潰瘍 / 体外衝撃波 / 強皮症 / インターフェロンα / 血管内皮 / 抗血管内皮細胞 / 血管炎症候群 / 抗血管内皮細胞抗体 / アポトーシス / 免疫学 / T細胞 / オートファジー / 膠原病学 … More Except Principal Investigator 転写因子GATA2 / 肺動脈性肺高血圧症 / lymph node metastasis / DDS / がん / リンパ節内投与 / 薬物送達 / 免疫療法 / 転移 / リンパ節 / 転写因子GATA3 / 2型自然リンパ球 / B細胞レパトア解析 / 抗CCP抗体 / 生物学的製剤 / BCRレパトア / ＢＣＲレパトア / TCRレパトア / アバタセプト / レパトア解析 / 関節リウマチ / Toll様受容体 / 骨髄由来免疫抑制細胞 / 転写因子ＧＡＴＡ２ / マクロファージ / 単球 / 肺高血圧 Less

転移リンパ節に対するリンパ行性放射線免疫療法の開発
- Principal Investigator
  
  SUKHBAATAR ARIUNBUYAN
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
  Basic Section 90140:Medical technology assessment-related
  Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related
- Research Institution
  Tohoku University
抗核酸B細胞刺激モデルの樹立とSLEにおける形質芽細胞を標的とした治療標的の探索Principal Investigator
- Principal Investigator
  
  藤井博司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tohoku University
Innovative Lymphatic Immunotherapy for Metastatic Lymph Nodes
- Principal Investigator
  
  小玉哲也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tohoku University
Development of novel therapies targeting pathogenic plasmablasts in SLE based on gene expression of B cell subsetsPrincipal Investigator
- Principal Investigator
  
  Fujii Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tohoku University
The elucidation of molecular mechanism of extracorporeal shock wave therapy for skin ulcer in systemic sclerosisPrincipal Investigator
- Principal Investigator
  
  Fujii Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tohoku University
Development of a new rheumatoid arthritis monitoring method by analysis of anti-CCP antibody-producing B cell repertoire
- Principal Investigator
  
  ISHII Tomonori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tohoku University
The role of type 2 innate lymphoid cells in the pulmonary arterial hypertension
- Principal Investigator
  
  Shirota Yuko
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Tohoku University
Development of a novel therapeutic strategy targeting CD38+CD43+ B cell for SLE based on gene expression profilePrincipal Investigator
- Principal Investigator
  
  FUJII HIROSHI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Tohoku University
The role of myeloid derived suppressor cells and transcription factor GATA2 in collagen disease related pulmonary arterial hypertension
- Principal Investigator
  
  Shirota Yuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Tohoku University
Identification of novel autoantiges against anti-endothelial antibodies from collagen disease patients by flowcytometry.Principal Investigator
- Principal Investigator
  
  FUJII Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Tohoku University
Functional analysis of autophagy in T cells of healthy donors and SLE patientsPrincipal Investigator
- Principal Investigator
  
  FUJII Hiroshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Tohoku University

All 2023 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet+B cells in systemic lupus erythematosus.2023
- Author(s)
  Yasaka K, Yamazaki T, Sato H, Shirai T, Cho M, Ishida K, Ito K, Tanaka T, Ogasawara K, Harigae H, Ishii T, Fujii H.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 25 Issue: 1 Pages: 200-200
- DOI
  10.1186/s13075-023-03186-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-21K08452, KAKENHI-PROJECT-21K08469
[Journal Article] Non-immunoglobulin G4-related multifocal fibrosclerosis presenting generalized morphea-like skin lesions.2021
- Author(s)
  Chiba T, Mizuashi M, Tamabuchi E, Kanbayashi Y, Shirota Y, Fujii H, Yamasaki K, Aiba S.
- Journal Title
  
  J Dermatol.
  
  Volume: 48 Issue: 6 Pages: 271-272
- DOI
  10.1111/1346-8138.15867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-21K08444
[Journal Article] Migratory Aortitis Associated with Granulocyte-colony-stimulating Factor2020
- Author(s)
  Shirai Tsuyoshi、Komatsu Hiroka、Sato Hiroko、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 12 Pages: 1559-1563
- DOI
  10.2169/internalmedicine.4331-19
- NAID
  130007854988
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-06-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08401, KAKENHI-PROJECT-18K16136
[Journal Article] High Relapse Rate in Patients with Polymyalgia Rheumatica despite the Combination of Immunosuppressants and Prednisolone: A Single Center Experience of 89 patients2020
- Author(s)
  Okazaki Soshi、Watanabe Ryu、Kondo Hinako、Kudo Masataka、Harigae Hideo、Fujii Hiroshi
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 251 Issue: 2 Pages: 125-133
- DOI
  10.1620/tjem.251.125
- NAID
  130007864039
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17418, KAKENHI-PROJECT-18K08401
[Journal Article] Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.2020
- Author(s)
  Mutoh T, Shirai T, Ishii T, Shirota Y, Fujishima F, Takahashi F, Kakuta Y, Kanazawa Y, Masamune A, Saiki Y, Harigae H, Fujii H.
- Journal Title
  
  Nat Commun.
  
  Volume: 11(1) Issue: 1 Pages: 1-13
- DOI
  10.1038/s41467-020-15088-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-18K08401, KAKENHI-PROJECT-18K16136
[Journal Article] Better Retention of Abatacept Is Associated with High Rheumatoid Factor: A Five-Year Follow-Up Study of Patients with Rheumatoid Arthritis2020
- Author(s)
  Okazaki Soshi、Watanabe Ryu、Harigae Hideo、Fujii Hiroshi
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 250 Issue: 3 Pages: 153-159
- DOI
  10.1620/tjem.250.153
- NAID
  130007805117
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08401
[Journal Article] Comment on: Aortarctia: a rare manifestation of relapsing polychondrits2020
- Author(s)
  Shirai Tsuyoshi、Murakami Koji、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  Rheumatology
  
  Volume: 59 Issue: 7 Pages: 1784-1785
- DOI
  10.1093/rheumatology/keaa019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08401, KAKENHI-PROJECT-18K16136
[Journal Article] JAK2 mutation?positive polycythaemia vera associated with IgA vasculitis and nephrotic syndrome: a case report2020
- Author(s)
  Kondo Hinako、Watanabe Ryu、Okazaki Soshi、Kuriyama Kaori、Ochi Tetsuro、Yamada Gen、Sugiura Akira、Chiba Hiromu、Tsukada Akira、Taniuchi Shinji、Igarashi Takehiko、Kudo Masataka、Harigae Hideo、Fujii Hiroshi
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: 4 Issue: 2 Pages: 289-295
- DOI
  10.1080/24725625.2020.1728061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17418, KAKENHI-PROJECT-18K08401
[Journal Article] Successful Treatment of Pulmonary Arterial Hypertension in Systemic Sclerosis with Anticentriole Antibody.2020
- Author(s)
  Ishii Y, Fujii H, Sugimura K, Shirai T, Hoshi Y, Fujita Y, Shirota Y, Ishii T, Shimokawa H, Harigae H.
- Journal Title
  
  Case Rep Rheumatol.
  
  Volume: 2020 Pages: 1-7
- DOI
  10.1155/2020/1926908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-18K08401, KAKENHI-PROJECT-18K16136
[Journal Article] Refractory Takayasu arteritis successfully treated with rituximab: case-based review.2019
- Author(s)
  Mutoh T, Ishii T, Shirai T, Akita K, Kamogawa Y, Fujita Y, Sato H, Shirota Y, Fujii H, Harigae H.
- Journal Title
  
  Rheumatol Int.
  
  Volume: 39(11) Issue: 11 Pages: 1989-1994
- DOI
  10.1007/s00296-019-04390-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09965
[Journal Article] Insufficient Use of Corticosteroids without Immunosuppressants Results in Higher Relapse Rates in Takayasu Arteritis2019
- Author(s)
  Mutoh Tomoyuki、Shirai Tsuyoshi、Fujii Hiroshi、Ishii Tomonori、Harigae Hideo
- Journal Title
  
  The Journal of Rheumatology
  
  Volume: 47 Issue: 2 Pages: 255-263
- DOI
  10.3899/jrheum.181219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16136, KAKENHI-PROJECT-17K08973
[Journal Article] Four distinct clinical phenotypes of vasculitis affecting medium-sized arteries.2019
- Author(s)
  Shirai T, Shirota Y, Fujii H, Ishii T, Harigae H.
- Journal Title
  
  Scand J Rheumatol
  
  Volume: 48 Issue: 4 Pages: 1-7
- DOI
  10.1080/03009742.2018.1551965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-18K16136, KAKENHI-PROJECT-17K08973
[Journal Article] Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis (AAV) Restricted to the Limbs2018
- Author(s)
  Ojima Y, Sawada K, Fujii H, Shirai T, Saito A, Kagaya S, Aoki S, Takeuchi Y, Ishii T, Nagasawa T.
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 9 Pages: 1301-1308
- DOI
  10.2169/internalmedicine.9848-17
- NAID
  130006730798
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-05-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-15K09515
[Journal Article] Successful Cord Blood Stem Cell Transplantation for Primary Cutaneous CD8-positive Aggressive Epidermotropic Cytotoxic T-cell Lymphoma Complicated with Cerebral Infiltration2018
- Author(s)
  Ichikawa S, Fukuhara N, Hatta S, Himuro M, Katsushima H, Nasu K, Ono K, Inokura K, Kobayashi M, Onishi Y, Fujii H, Ishizawa K, Ichinohasama R, Harigae H.
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 14 Pages: 2051-2055
- DOI
  10.2169/internalmedicine.0568-17
- NAID
  130007404899
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-07-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16176, KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-15K09515, KAKENHI-PROJECT-16K19564, KAKENHI-PROJECT-18K07435
[Journal Article] Multicenter double-blind randomized controlled trial to evaluate the effectiveness and safety of bortezomib as a treatment for refractory systemic lupus erythematosus.2018
- Author(s)
  Ishii T, Tanaka Y, Kawakami A, Saito K, Ichinose K, Fujii H, Shirota Y, Shirai T, Fujita Y, Watanabe R, Chiu SW, Yamaguchi T, Harigae H.
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 6 Pages: 1-7
- DOI
  10.1080/14397595.2018.1432331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-15K09515, KAKENHI-PROJECT-18K16136
[Journal Article] Takayasu Arteritis Coexisting with Sclerosing Osteomyelitis2018
- Author(s)
  Shirai T, Hanaoka R, Goto Y, Kojima I, Ishii Y, Hoshi Y, Fujita Y, Shirota Y, Fujii H, Ishii T, Harigae H.
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 13 Pages: 1929-1934
- DOI
  10.2169/internalmedicine.0329-17
- NAID
  130007387190
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-18K16136, KAKENHI-PROJECT-15K11287
[Journal Article] Nasal Septal Perforation in Propylthiouracil-Induced Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis.2018
- Author(s)
  Ishii Y, Shirai T, Hoshi Y, Fujita Y, Shirota Y, Fujii H, Ishii T, Harigae H.
- Journal Title
  
  Case Rep Rheumatol.
  
  Volume: 2018 Pages: 4-4
- DOI
  10.1155/2018/8192021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09965
[Journal Article] Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity.2017
- Author(s)
  Ikeda T, Fujii H, Nose M, Kamogawa Y, Shirai T, Shirota Y, Ishii T, Harigae H.
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 19（1） Issue: 1 Pages: 187-187
- DOI
  10.1186/s13075-017-1397-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-15K09515
[Journal Article] Relapsing Polychondritis Complicated by Myelodysplastic Syndrome Is Resistant to Immunosuppression: Comment on the Article by Dion et al.2017
- Author(s)
  Shirai T, Fujii H, Saito R, Nasu K, Kamogawa Y, Fukuhara N, Fujita Y, Shirota Y, Ishii T, Harigae H.
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: 69 Issue: 3 Pages: 682-683
- DOI
  10.1002/art.39969
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H06642, KAKENHI-PROJECT-26461457, KAKENHI-PROJECT-17K08973, KAKENHI-PROJECT-17K09965, KAKENHI-PROJECT-15K09515
[Journal Article] Tolerogenic immunoreceptor ILT3/LILRB4 paradoxically marks pathogenic auto-antibody-producing plasmablasts and plasma cells in non-treated SLE.2016
- Author(s)
  Inui M, Sugahara-Tobinai A, Fujii H, Itoh-Nakadai A, Fukuyama H, Kurosaki T, Ishii T, Harigae H, Takai T.
- Journal Title
  
  International Immunology
  
  Volume: 28 Issue: 3 Pages: 597-604
- DOI
  10.3109/14397595.2015.1012797
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09515
[Journal Article] Human CD43+ B cells are closely related not only to memory B cells phenotypically but also to plasmablasts developmentally in healthy individuals.2015
- Author(s)
  Inui M, Hirota S, Hirano K, Fujii H, Sugahara-Tobinai A, Ishii T, Harigae H, Takai T
- Journal Title
  
  Internationa Immunology
  
  Volume: 27 Issue: 7 Pages: 345-55
- DOI
  10.1093/intimm/dxv009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09515, KAKENHI-PROJECT-26461597
[Journal Article] A novel autoantibody against ephrin type B receptor 2 in acute necrotizing encephalopathy.2013
- Author(s)
  Shirai T, Fujii H, Ono M, Watanabe R, Shirota Y, Saito S, Ishii T, Nose M, Harigae H.
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 10 Issue: 1 Pages: 128-128
- DOI
  10.1186/1742-2094-10-128
- Data Source
  KAKENHI-PROJECT-24591438
[Journal Article] An innovative method to identify autoantigens expressed on the endothelial cell surface: serological identification system for autoantigens using a retroviral vector and flow cytometry (SARF).2013
- Author(s)
  Shirai T, Fujii H, Ono M, Watanabe R, Ishii T, Harigae H
- Journal Title
  
  Clin Dev Immunol.
  
  Volume: 2013 Pages: 128-134
- DOI
  10.1155/2013/453058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591438
[Journal Article] A novel autoantibody against fibronectin leucine-rich transmembrane protein 2 expressed on the endothelial cell surface identified by retroviral vector system in systemic lupus erythematosus.2012
- Author(s)
  Shirai T, Fujii H, Ono M, Nakamura K, Watanabe R, Tajima Y, Takasawa N, Ishii T, Harigae H.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 14 Issue: 4
- DOI
  10.1186/ar3897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591438
[Presentation] 膠原病性肺動脈性肺高血圧症における各種自己抗体別にみた長期予後の違いについての検討.2019
- Author(s)
  城田祐子 , 白井剛志, 藤井博司, 小寺隆雄, 亀岡淳一, 石井智徳, 張替秀郎
- Organizer
  第63回　日本リウマチ学会学術集会総会.
- Data Source
  KAKENHI-PROJECT-17K09965
[Presentation] 膠原病性肺動脈性肺高血圧症における予後予測因子と死因について2018
- Author(s)
  城田祐子, 星陽介,佐藤紘子, 藤田洋子, 白井剛志, 藤井博司, 石井智徳, 張替秀郎.
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K09965
[Presentation] リウマチ性疾患の合併症(感染症以外・アミロイドーシス・その他)3:その他2 膠原病性肺動脈性肺高血圧症(CTD-PAH)における予後予測因子と死因について2018
- Author(s)
  城田祐子, 星陽介, 佐藤紘子, 藤田洋子, 白井剛志, 藤井博司, 石井智徳, 張替秀郎
- Organizer
  日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-17K08973
[Presentation] 強皮症・MCTD・重複症候群1 全身性強皮症に伴う難治性皮膚潰瘍に対する低出力衝撃波療法の有効性・安全性検証試験2018
- Author(s)
  石井智徳(東北大学病院臨床研究推進センター), 川口鎮司, 石川治, 竹森弘光, 高澤徳彦, 小林仁, 安岡秀剛, 高橋裕一, 小寺隆雄, 高井修, 中屋来哉, 泉山朋政, 齋藤真一郎, 鴨川由起子, 藤田洋子, 白井剛志, 城田祐子, 藤井博司, 張替秀郎
- Organizer
  日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-17K08973
[Presentation] Autoantibodies and Clinical outcome in Pulmonary Arterial Hypertension associated with Connective Tissue Diseases.2018
- Author(s)
  Shirota Y, Shirai T, Fujii H, Ishii T, Harigae H.
- Organizer
  Annual Meeting of American Collage of Rheumatorogy 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09965
[Presentation] 高疾患活動性ループスモデルマウスへのボルテゾミブ投与による致死的毒性について2017
- Author(s)
  藤井博司、能勢眞人、武藤智之、秋田佳奈恵、鴨川由起子、白井剛志、城田祐子、石井智徳、張替秀郎
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K09515
[Presentation] 11C-BF-227-PETによる全身アミロイド計測を試みたアミロイドーシス6症例の検討2017
- Author(s)
  城田祐子、石井悠翔、星陽介、藤田洋子、白井剛志、藤井博司、石井智徳、張替秀郎
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K09965
[Presentation] Four-Distinct Phenotypes of Patients with Necrotizing Arteritis of Medium and Small Artery2017
- Author(s)
  Ishii T, Kawaguchi Y, Ishikawa O, Takasawa N, Kodera T, Yasuoka H, Takahashi Y, Takai O, Nakaya I, Fujii H, Kamogawa Y, Shirota Y, Shirai T, Fujita Y, Saito S, Shimokawa H and Harigae H.
- Organizer
  2017 ACR/ARHP Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08973
[Presentation] 強皮症とシェーグレン症候群合併肺動脈性肺高血圧症の治療2016
- Author(s)
  城田祐子、石井悠翔、星陽介、藤田洋子、白井剛志、藤井博司、杉村宏一郎、下川宏明、石井智徳、張替秀郎
- Organizer
  第1回日本肺高血圧・肺循環学会学術集会
- Place of Presentation
  京王プラザホテル(東京）
- Year and Date
  2016-10-01
- Data Source
  KAKENHI-PROJECT-26461457
[Presentation] 膠原病関連肺動脈性肺高血圧症（CTD－PAH）における活動性・長期予後の検討－集学的免疫抑制療法の効果について-2016
- Author(s)
  城田祐子、武藤智之、町山智章、秋田佳奈恵、鴨川由起子、藤田洋子、藤井博司、石井智徳、張替秀郎
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-04-23
- Data Source
  KAKENHI-PROJECT-26461457
[Presentation] Longer suppression of anti deDNA antibody by sequential therapy with bortezomib and cyclophosphamide in lupus model mouse2016
- Author(s)
  藤井博司、能勢眞人、武藤智之、秋田佳奈恵、鴨川由起子、藤田洋子、城田祐子、石井智徳、張替秀郎
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-15K09515
[Presentation] Positron Emission Tomography Images with an Amyloid-Specific Tracer 11C-BF-227 in Systemic Amyloidosis Patients2016
- Author(s)
  Yuko Shirota, Katsutoshi Furukawa, Manabu Tashiro, Tsuyoshi Shirai, Hiroshi Fujii, Tomonori Ishii, Hideo Harigae
- Organizer
  2016ACR　Annual Meeting
- Place of Presentation
  Walter E. Washington Convention Center（USA)
- Year and Date
  2016-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461457
[Presentation] Bortezomib Treatment Induces Higher Mortality Rate in Lupus Model Mice with High Disease Activity2016
- Author(s)
  Hiroshi Fujii, Tomoko Ikeda, Masao Nose, Tomoyuki Muto, Kanae Akita, Yukiko Kamogawa, Tsuyoshi Shirai, Tomonori Ishii, Hideo Harigae
- Organizer
  2016ACR　Annual Meeting
- Place of Presentation
  Walter E. Washington Convention Center (USA)
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09515
[Presentation] 難治性中耳炎で発症し、診断に苦慮したANCA関連血管炎性中耳炎（OMAAV)の一例2016
- Author(s)
  二宮高洋、城田祐子、星陽介、石井悠翔、藤田洋子、白井剛志、藤井博司、石井智徳、張替秀郎
- Organizer
  第26回日本リウマチ学会（JCR）北海道・東北支部学術集会
- Place of Presentation
  コラッセふくしま（福島県福島市）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-26461457
[Presentation] Cell cycle related gene signature and interferon inducible gene signature in circulating CD38+CD43+ B cell subset in B cell2015
- Author(s)
  Hiroshi Fujii, Tomoaki Machiyama, Kanae Akita, Yukiko Kamogawa, Ryu Watanabe, Yoko Fujita, Yuko Shirota, Tomonori Ishii, Hideo Harigae
- Organizer
  第59回日本リウマチ学会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15K09515
[Presentation] 発現クローニングシステム（SARF）を用いた高安動脈炎における新規膜蛋白自己抗原2種の同定2013
- Author(s)
  白井剛志、藤井博司、鴨川由起子、中村恭平、渡部龍、藤田洋子、城田祐子、斎藤真一郎、石井智徳、張替秀郎
- Organizer
  第57回日本リウマチ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591438
[Presentation] A novel method to identify autoantigens expressed on the cell surface: SARF2013
- Author(s)
  Tsuyoshi Shirai, Hiroshi Fujii, Masao Ono, Ryu Watanabe, Tomonori Ishii, Hideo Harigae
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  イタリア、ミラノ
- Data Source
  KAKENHI-PROJECT-24591438
[Presentation] フローサイトメトリーを用いたヒトプライマリT細胞におけるオートファジーの定量と機能解析2012
- Author(s)
  渡部龍、藤井博司、白井剛志、田島結実、高澤徳彦、石井智徳、張替秀郎
- Organizer
  日本分子生物学会第12回春季シンポジウム
- Place of Presentation
  山梨
- Year and Date
  2012-04-25
- Data Source
  KAKENHI-PROJECT-22790924
[Presentation] A Novel Method for Quantitative and Functional Analysis of Autophagy Using Flow Cytometry in Activated Human Primary T cells2012
- Author(s)
  Ryu Watanabe, Hiroshi Fujii, Yukiko Kamogawa, Kyohei Nakamura, Tsuyoshi Shirai, Yumi Tajima, Shinichiro Saito, Tomonori Ishii, Hideo Harigae
- Organizer
  America College of Rheumatology 2012
- Place of Presentation
  Washington, USA
- Data Source
  KAKENHI-PROJECT-24591438
[Presentation] 顕著な脳炎を呈した中枢神経ループス患者における新規抗EphB2自己抗体の同定2012
- Author(s)
  白井剛志、藤井博司、中村恭平、渡部龍、田島結実、高澤徳彦、石井智徳、張替秀郎
- Organizer
  第56回日本リウマチ学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-28
- Data Source
  KAKENHI-PROJECT-22790924
[Presentation] Retroviral vector system identified FLRT2 as a novel cell surface autoantigen against anti-endothelial cell antibody in systemic lupus erythematosus2011
- Author(s)
  白井剛志、藤井博司, 他
- Organizer
  日本リウマチ学会
- Place of Presentation
  横浜
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-22790924
[Presentation] レトロウィルスベクターシステムを用いた抗血管内皮細胞抗体対応自己抗原FLRT2の同定2011
- Author(s)
  白井剛志、藤井博司、中村恭平、渡部龍、田島結実、高澤徳彦、石井智徳、張替秀郎
- Organizer
  第55回日本リウマチ学会総会
- Place of Presentation
  神戸
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-22790924
[Presentation] Retroviral vector system identified FLRT2 as a novel cell surface autoantigen against anti-endothelial cell antibodies in systemic lupus erythematosus.2011
- Author(s)
  Shirai. T , Fujii. H, Ono. M, Takasawa. N , Ishii. T, Harigae. H.
- Organizer
  米国リウマチ学会(ACR)
- Place of Presentation
  シカゴ
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-22790924
[Presentation] Retroviral vector system identified FLRT2 as a novel cell surface autoantigen against anti-endothelial cell antibody in systemic lupus erythematosus2011
- Author(s)
  白井剛志、藤井博司, 他
- Organizer
  American college of rhumeatology
- Place of Presentation
  米国、シカゴ
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-22790924
[Presentation] hTERT insufficiency in rheumatoid arthritis causes PUMA-mediated T-cell apoptosis2010
- Author(s)
  藤井博司
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-22790924

1. Shirota Yuko (20455819)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
2. ISHII Tomonori (10282138)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
3. 藤原亨 (60333796)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 小玉哲也 (40271986)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SUKHBAATAR ARIUNBUYAN (20867147)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 小笠原康悦 (30323603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 白井剛志 (20646997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. 薮上信 (00302232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山口匡 (40334172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TANAKA Tetsuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 渡部龍

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

fujii hiroshi 藤井 博司

FUJII Hiroshi 藤井 博司

Research Projects

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Co-Researchers

転移リンパ節に対するリンパ行性放射線免疫療法の開発

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抗核酸B細胞刺激モデルの樹立とSLEにおける形質芽細胞を標的とした治療標的の探索Principal Investigator

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Innovative Lymphatic Immunotherapy for Metastatic Lymph Nodes

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Development of novel therapies targeting pathogenic plasmablasts in SLE based on gene expression of B cell subsetsPrincipal Investigator

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The elucidation of molecular mechanism of extracorporeal shock wave therapy for skin ulcer in systemic sclerosisPrincipal Investigator

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Development of a new rheumatoid arthritis monitoring method by analysis of anti-CCP antibody-producing B cell repertoire

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The role of type 2 innate lymphoid cells in the pulmonary arterial hypertension

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Development of a novel therapeutic strategy targeting CD38+CD43+ B cell for SLE based on gene expression profilePrincipal Investigator

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The role of myeloid derived suppressor cells and transcription factor GATA2 in collagen disease related pulmonary arterial hypertension

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Identification of novel autoantiges against anti-endothelial antibodies from collagen disease patients by flowcytometry.Principal Investigator

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Functional analysis of autophagy in T cells of healthy donors and SLE patientsPrincipal Investigator

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[Journal Article] Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet+B cells in systemic lupus erythematosus.2023

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[Journal Article] Non-immunoglobulin G4-related multifocal fibrosclerosis presenting generalized morphea-like skin lesions.2021

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fujii hiroshi 藤井博司

FUJII Hiroshi 藤井博司