Abe Shinya 阿部真也

Researcher Number	70972678
Other IDs
Affiliation (Current)	2026: 東京科学大学, 総合研究院, 助教
Affiliation (based on the past Project Information) *help	2024 – 2025: 東京科学大学, 総合研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related Except Principal Investigator Basic Section 49070:Immunology-related / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator 母体代謝 / 肝臓 / クッパー細胞 Except Principal Investigator 抗ウイルス免疫応答 / 腫瘍免疫 / IL-15 / 微小環境 / サイトカイン / 自然免疫 / リンパ洞 … More / 薬物動態 / リンパ節転移 / リンパ行性薬物送達法 / 交通亢進 Less

Kupffer細胞による母体肝臓の脂質代謝制御と胎児連関の解明Principal Investigator
- Principal Investigator
  
  阿部真也
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Institute of Science Tokyo
Development of Innovative LDDS-based Immunochemotherapy Targeting Lymph Nodes with Enhanced Sinus and Vascular Connectivity
- Principal Investigator
  
  小玉哲也
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tohoku University
Control of immune response and tissue homeostasis by novel IL-15-dependent innate lymphocytes
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University

All 2025 2024 2023

All Journal Article Presentation

[Journal Article] IL-7Rα signaling in regulatory T cells of adipose tissue is essential for systemic glucose homeostasis2025
- Author(s)
  Tani-ichi Shizue、Abe Shinya、Miyachi Hitoshi、Kitano Satsuki、Shimba Akihiro、Ejima Aki、Hara Takahiro、Cui Guangwei、Kado Tomonobu、Hori Shohei、Tobe Kazuyuki、Ikuta Koichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: . Issue: 4 Pages: 666-679
- DOI
  10.1093/jimmun/vkae064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-23K27426
[Journal Article] The transcription factor RORα is required for the development of type 1 innate lymphoid cells in adult bone marrow2025
- Author(s)
  Abe Shinya、Kagao Moe、Asahi Takuma、Kato Ryoma、Tani-ichi Shizue、Shimba Akihiro、Ishibashi Riki、Miyachi Hitoshi、Kitano Satsuki、Miyazaki Masaki、Rodewald Hans-Reimer、Toyoshima Fumiko、Ikuta Koichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: - Issue: 4 Pages: 575-581
- DOI
  10.1093/jimmun/vkaf001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-23K27426
[Journal Article] A feedback amplifier circuit with Notch and E2A orchestrates T-cell fate and suppresses the innate lymphoid cell lineages during thymic ontogeny2025
- Author(s)
  Miyazaki Kazuko、Horie Kenta、Watanabe Hitomi、Hidaka Reiko、Hayashi Rinako、Hayatsu Norihito、Fujiwara Kentaro、Kuwata Rei、Uehata Takuya、Ochi Yotaro、Takenaka Makoto、Kawaguchi Risa Karakida、Ikuta Koichi、Takeuchi Osamu、Ogawa Seishi、Hozumi Katsuto、Holl?nder Georg A.、Kondoh Gen、Akiyama Taishin、Miyazaki Masaki
- Journal Title
  
  Genes & Development
  
  Volume: 39 Issue: 5-6 Pages: 384-400
- DOI
  10.1101/gad.352111.124
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00402, KAKENHI-PROJECT-23K27399, KAKENHI-PROJECT-23K27425, KAKENHI-PROJECT-23K27426, KAKENHI-PROJECT-24K10051, KAKENHI-PROJECT-23K14165, KAKENHI-PROJECT-23KK0139
[Journal Article] A RORE-dependent Intronic Enhancer in the IL-7 Receptor-α Locus Controls Glucose Metabolism via Vγ4+ γδT17 Cells2024
- Author(s)
  Shizue Tani-Ichi, David Obwegs, Alice Yoshikawa, Hitomi Watanabe, Satsuki Kitano, Aki Ejima, Shinya Hatano, Hitoshi Miyachi, Guangwei Cui, Akihiro Shimba, Shinya Abe, Shohei Hori, Gen Kondoh, Sagar Sagar, Yasunobu Yoshikai, Koichi Ikuta
- Journal Title
  
  The Journal of Immunology
  
  Volume: 213 Issue: 3 Pages: 283-295
- DOI
  10.4049/jimmunol.2300450
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05191, KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-22K19422, KAKENHI-PROJECT-23K27426
[Journal Article] Insights into the heterogeneity of iNKT cells: tissue-resident and circulating subsets shaped by local microenvironmental cues2024
- Author(s)
  Cui, G., Abe, S., Kato, R., and Ikuta, K.
- Journal Title
  
  Front. Immunol.
  
  Volume: 15 Pages: 1349184-1349184
- DOI
  10.3389/fimmu.2024.1349184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27426
[Journal Article] A Chimeric IL-7Rα/IL-2Rβ Receptor Promotes the Differentiation of T Cell Progenitors into B Cells and Type 2 Innate Lymphoid Cells2024
- Author(s)
  Shimba Akihiro、Tani-ichi Shizue、Masuda Kyoko、Cui Guangwei、Munakata Satoru、Abe Shinya、Kitano Satsuki、Miyachi Hitoshi、Kawamoto Hiroshi、Ikuta Koichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 213 Issue: 7 Pages: 952-964
- DOI
  10.4049/jimmunol.2300483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-23K27426
[Journal Article] Control of the development, distribution, and function of innate-like lymphocytes and innate lymphoid cells by the tissue microenvironment2024
- Author(s)
  Ikuta, K., Asahi, T., Cui, G., Abe, S., and Takami, D.
- Journal Title
  
  Adv. Exp. Med. Biol.
  
  Volume: 1444 Pages: 111-127
- DOI
  10.1007/978-981-99-9781-7_8
- ISBN
  9789819997800, 9789819997817
- Data Source
  KAKENHI-PROJECT-23K27426
[Journal Article] Lung group 2 innate lymphoid cells differentially depend on local IL-7 for their distribution, activation, and maintenance in innate and adaptive immunity-mediated airway inflammation2023
- Author(s)
  Takami Daichi、Abe Shinya、Shimba Akihiro、Asahi Takuma、Cui Guangwei、Tani-ichi Shizue、Hara Takahiro、Miyata Keishi、Ikutani Masashi、Takatsu Kiyoshi、Oike Yuichi、Ikuta Koichi
- Journal Title
  
  International Immunology
  
  Volume: 35 Issue: 11 Pages: 513-530
- DOI
  10.1093/intimm/dxad029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-23K27426
[Journal Article] Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches2023
- Author(s)
  Asahi Takuma、Abe Shinya、Cui Guangwei、Shimba Akihiro、Nabekura Tsukasa、Miyachi Hitoshi、Kitano Satsuki、Ohira Keizo、Dijkstra Johannes M、Miyazaki Masaki、Shibuya Akira、Ohno Hiroshi、Ikuta Koichi
- Journal Title
  
  eLife
  
  Volume: 12 Pages: 1-22
- DOI
  10.7554/elife.84209
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-22K19430, KAKENHI-PROJECT-23K27425, KAKENHI-PROJECT-23K27426
[Journal Article] CD45 alleviates airway inflammation and lung fibrosis by limiting expansion and activation of ILC2s2023
- Author(s)
  Cui Guangwei、Shimba Akihiro、Jin Jianshi、Hojo Nozomi、Asahi Takuma、Abe Shinya、Ejima Aki、Okada Shinri、Ohira Keizo、Kato Ryoma、Tani-ichi Shizue、Yamada Ryo、Ebihara Takashi、Shiroguchi Katsuyuki、Ikuta Koichi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 36
- DOI
  10.1073/pnas.2215941120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-21K19368, KAKENHI-PROJECT-23K27426, KAKENHI-PROJECT-21H02707
[Journal Article] Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow2023
- Author(s)
  Abe Shinya、Asahi Takuma、Hara Takahiro、Cui Guangwei、Shimba Akihiro、Tani-ichi Shizue、Yamada Kohei、Miyazaki Kazuko、Miyachi Hitoshi、Kitano Satsuki、Nakamura Naotoshi、Kikuta Junichi、Vandenbon Alexis、Miyazaki Masaki、Yamada Ryo、Ohteki Toshiaki、Ishii Masaru、Sexl Veronika、Nagasawa Takashi、Ikuta Koichi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 9 Pages: 113127-113127
- DOI
  10.1016/j.celrep.2023.113127
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-21K08370, KAKENHI-PROJECT-22K19430, KAKENHI-PUBLICLY-22H05627, KAKENHI-PROJECT-23K24152, KAKENHI-PROJECT-23K27425, KAKENHI-PROJECT-23K27426
[Presentation] Development and heterogeneity of group 1 innate lymphoid cells2024
- Author(s)
  Koichi Ikuta, Takuma Asahi, and Shinya Abe
- Organizer
  第53回日本免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27426
[Presentation] Bone marrow microenvironment for NK cell differentiation and localization2024
- Author(s)
  阿部真也、榛葉旭恒、谷一靖江、長澤丘司、生田宏一
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27426
[Presentation] 転写因子RORaによる１型自然リンパ球の分化制御2023
- Author(s)
  阿部真也、加々尾萌絵、生田宏一
- Organizer
  Kyoto T Cell Conference 第31回学術集会
- Data Source
  KAKENHI-PROJECT-23K27426

1. 小玉哲也 (40271986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SUKHBAATAR ARIUNBUYAN (20867147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 藤井博司 (30531321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 西條憲 (70636729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 片桐克則 (10455842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 生田宏一 (90193177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 榛葉旭恒 (30812242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 谷一靖江 (50432331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 堀昌平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 竹内理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Abe Shinya 阿部 真也

Research Projects

Research Products

Co-Researchers

Kupffer細胞による母体肝臓の脂質代謝制御と胎児連関の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Innovative LDDS-based Immunochemotherapy Targeting Lymph Nodes with Enhanced Sinus and Vascular Connectivity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Control of immune response and tissue homeostasis by novel IL-15-dependent innate lymphocytes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] IL-7Rα signaling in regulatory T cells of adipose tissue is essential for systemic glucose homeostasis2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The transcription factor RORα is required for the development of type 1 innate lymphoid cells in adult bone marrow2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A feedback amplifier circuit with Notch and E2A orchestrates T-cell fate and suppresses the innate lymphoid cell lineages during thymic ontogeny2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A RORE-dependent Intronic Enhancer in the IL-7 Receptor-α Locus Controls Glucose Metabolism via Vγ4+ γδT17 Cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insights into the heterogeneity of iNKT cells: tissue-resident and circulating subsets shaped by local microenvironmental cues2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Chimeric IL-7Rα/IL-2Rβ Receptor Promotes the Differentiation of T Cell Progenitors into B Cells and Type 2 Innate Lymphoid Cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Control of the development, distribution, and function of innate-like lymphocytes and innate lymphoid cells by the tissue microenvironment2024

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Lung group 2 innate lymphoid cells differentially depend on local IL-7 for their distribution, activation, and maintenance in innate and adaptive immunity-mediated airway inflammation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD45 alleviates airway inflammation and lung fibrosis by limiting expansion and activation of ILC2s2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] Development and heterogeneity of group 1 innate lymphoid cells2024

Author(s)

Abe Shinya 阿部真也