Shimba Akihiro 榛葉旭恒

Researcher Number	30812242
Other IDs
Affiliation (Current)	2022: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2019 – 2022: 京都大学, 医学研究科, 助教 2018: 京都大学, ウイルス・再生医科学研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related Except Principal Investigator Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 49070:Immunology-related
Keywords	Principal Investigator ストレス / 大腸炎 / 炎症性腸疾患 / グルココルチコイド / Th17細胞 / ILC3 / ステロイドホルモン / ＴＨ17 / レニン / ヘルパーT細胞 … More / 精神的ストレス / TH17細胞 / TH17 / マトリックスメタロプロテアーゼ / 関節リウマチ … More Except Principal Investigator グルココルチコイド / 自己免疫疾患 / Th17細胞 / 実験的自己免疫性脳脊髄炎 / 関節リウマチ / 自然免疫 / サイトカイン / 微小環境 / 腫瘍免疫 / IL-15 Less

ストレスがTH17細胞のプロテアーゼの発現上昇と関節炎増悪に寄与する機構の解明Principal Investigator
- Principal Investigator
  
  榛葉旭恒
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
Induction of autoimmune diseases by glucocorticoids
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kyoto University
ストレスがレニンによるTH17細胞の活性化を介して腸管炎症を惹起する機構の解明Principal Investigator
- Principal Investigator
  
  榛葉旭恒
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
IL-15-producing microenvironment supporting innate lymphoid cells and its role in diseases
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
Glucocorticoids enhance the differentiation and function of Th17 cells and cause colitisPrincipal Investigator
- Principal Investigator
  
  Shimba Akihiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University

All 2021 2020 2019

All Journal Article Presentation

[Journal Article] Pleiotropic Effects of Glucocorticoids on the Immune System in Circadian Rhythm and Stress2021
- Author(s)
  Akihiro Shimba, Aki Ejima, Koichi Ikuta
- Journal Title
  
  Front Immunol
  
  Volume: 706951
- DOI
  10.3389/fimmu.2021.706951
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16280
[Journal Article] Glucocorticoids Regulate Circadian Rhythm of Innate and Adaptive Immunity2020
- Author(s)
  Shimba A. and Ikuta K.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 2143-2143
- DOI
  10.3389/fimmu.2020.02143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K16280
[Journal Article] Immune-enhancing effects of glucocorticoids in response to day?night cycles and stress2020
- Author(s)
  Shimba A. and Ikuta K.
- Journal Title
  
  International Immunology
  
  Volume: 32 Pages: 703-708
- DOI
  10.1093/intimm/dxaa048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K16280
[Journal Article] Acceleration of immune senescence-mediated ageing process by long-term circadian misalignment.2020
- Author(s)
  Inokawa Hitoshi, Umemura Yasuhiro, Shimba Akihiro, Kawakami Eiryo, Koike Nobuya, Tsuchiya Yoshiki, Ohashi Munehiro, Minami Yoichi, Cui Guangwei, Asahi Takuma, Ono Ryutaro, Sasawaki Yuh, Konishi Eiichi, Yoo Seung-Hee, Chen Zheng, Teramukai Satoshi, Ikuta Koichi, Yagita Kazuhiro
- Journal Title
  
  Sci Rep
  
  Volume: 10 Pages: 2569-2569
- DOI
  10.1038/s41598-020-59541-y
- NAID
  120006799241
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600, KAKENHI-PROJECT-17K11021, KAKENHI-PROJECT-17KT0129, KAKENHI-PROJECT-18K15184
[Journal Article] Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intraepithelial lymphocytes in the intestine.2020
- Author(s)
  Zhu Yuanbo、Cui Guangwei、Miyauchi Eiji、Nakanishi Yuki、Mukohira Hisa、Shimba Akihiro、Abe Shinya、Tani-ichi Shizue、Hara Takahiro、Nakase Hiroshi、Chiba Tsutomu、Sehara-Fujisawa Atsuko、Seno Hiroshi、Ohno Hiroshi、Ikuta Koichi
- Journal Title
  
  Int Immunol
  
  Volume: 32 Pages: 307-319
- DOI
  10.1093/intimm/dxz082
- NAID
  120006846480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-19K07604, KAKENHI-PROJECT-19K16687, KAKENHI-PROJECT-19K16712, KAKENHI-PROJECT-20K16280, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-18K07958
[Journal Article] Control of immunity by glucocorticoids in health and disease2020
- Author(s)
  Shimba A. and Ikuta K.
- Journal Title
  
  Seminars in Immunopathology
  
  Volume: 42 Pages: 669-680
- DOI
  10.1007/s00281-020-00827-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K16280
[Presentation] 胎児肝臓に由来する1型自然リンパ球の同定2021
- Author(s)
  旭拓真、阿部真也、崔広為、榛葉旭恒、生田宏一
- Organizer
  Kyoto T Cell Conference 第30回学術集会
- Data Source
  KAKENHI-PROJECT-20K21525
[Presentation] ステロイドホルモンによる免疫機能とアレルギーの制御2021
- Author(s)
  生田宏一、榛葉旭恒、江島亜希
- Organizer
  日本アレルギー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] Control of T cell immunity by glucocorticoids2021
- Author(s)
  榛葉旭恒、生田宏一
- Organizer
  第28回日本時間生物学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16280
[Presentation] 胎児肝臓に由来する1型自然リンパ球の同定2021
- Author(s)
  旭拓真、阿部真也、崔広為、榛葉旭恒、生田宏一
- Organizer
  Kyoto T Cell Conference 第30回学術集会
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] ステロイドホルモンによる免疫機能とアレルギーの制御2021
- Author(s)
  生田宏一、榛葉旭恒、江島亜希
- Organizer
  日本アレルギー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21525
[Presentation] ストレスはグルココルチコイドを介してTh17細胞を活性化する2021
- Author(s)
  榛葉旭恒、生田宏一
- Organizer
  第30回Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-20K16280
[Presentation] ストレスはグルココルチコイドを介してTh17細胞の分化を促進し腸炎を増悪させる2021
- Author(s)
  榛葉旭恒、生田宏一
- Organizer
  Kyoto T Cell Conference 第30回学術集会
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] ストレスはグルココルチコイドを介してTh17細胞の分化を促進し腸炎を増悪させる2021
- Author(s)
  榛葉旭恒、生田宏一
- Organizer
  Kyoto T Cell Conference 第30回学術集会
- Data Source
  KAKENHI-PROJECT-20K21525
[Presentation] Control of immunity by glucocorticoids2019
- Author(s)
  Shimba Akihiro
- Organizer
  第４８回日本免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15184
[Presentation] Glucocorticoids enhance T cell immune response.2019
- Author(s)
  榛葉旭恒
- Organizer
  日本免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15184

1. 生田宏一 (90193177)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 崔广為 (70791276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 谷一靖江 (50432331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. UMEMURA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. HARA Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 八木田和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 南陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 宮内栄治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中西祐貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 千葉勉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimba Akihiro 榛葉 旭恒

Research Projects

Research Products

Co-Researchers

ストレスがTH17細胞のプロテアーゼの発現上昇と関節炎増悪に寄与する機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Induction of autoimmune diseases by glucocorticoids

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ストレスがレニンによるTH17細胞の活性化を介して腸管炎症を惹起する機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

IL-15-producing microenvironment supporting innate lymphoid cells and its role in diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Glucocorticoids enhance the differentiation and function of Th17 cells and cause colitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Pleiotropic Effects of Glucocorticoids on the Immune System in Circadian Rhythm and Stress2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glucocorticoids Regulate Circadian Rhythm of Innate and Adaptive Immunity2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immune-enhancing effects of glucocorticoids in response to day?night cycles and stress2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acceleration of immune senescence-mediated ageing process by long-term circadian misalignment.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intraepithelial lymphocytes in the intestine.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Control of immunity by glucocorticoids in health and disease2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 胎児肝臓に由来する1型自然リンパ球の同定2021

Author(s)

Organizer

Data Source

[Presentation] ステロイドホルモンによる免疫機能とアレルギーの制御2021

Author(s)

Organizer

Data Source

[Presentation] Control of T cell immunity by glucocorticoids2021

Author(s)

Organizer

Data Source

[Presentation] 胎児肝臓に由来する1型自然リンパ球の同定2021

Author(s)

Shimba Akihiro 榛葉旭恒