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Shimba Akihiro  榛葉 旭恒

ORCIDConnect your ORCID iD *help
Researcher Number 30812242
Other IDs
Affiliation (Current) 2022: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help 2019 – 2022: 京都大学, 医学研究科, 助教
2018: 京都大学, ウイルス・再生医科学研究所, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 49070:Immunology-related
Except Principal Investigator
Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 49070:Immunology-related
Keywords
Principal Investigator
ストレス / 大腸炎 / 炎症性腸疾患 / グルココルチコイド / Th17細胞 / ILC3 / ステロイドホルモン / TH17 / レニン / ヘルパーT細胞 … More / 精神的ストレス / TH17細胞 / TH17 / マトリックスメタロプロテアーゼ / 関節リウマチ … More
Except Principal Investigator
グルココルチコイド / 自己免疫疾患 / Th17細胞 / 実験的自己免疫性脳脊髄炎 / 関節リウマチ / 自然免疫 / サイトカイン / 微小環境 / 腫瘍免疫 / IL-15 Less
  • Research Projects

    (5 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (10 People)
  •  ストレスがTH17細胞のプロテアーゼの発現上昇と関節炎増悪に寄与する機構の解明Principal Investigator

    • Principal Investigator
      榛葉 旭恒
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Kyoto University
  •  Induction of autoimmune diseases by glucocorticoids

    • Principal Investigator
      生田 宏一
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Kyoto University
  •  ストレスがレニンによるTH17細胞の活性化を介して腸管炎症を惹起する機構の解明Principal Investigator

    • Principal Investigator
      榛葉 旭恒
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Kyoto University
  •  IL-15-producing microenvironment supporting innate lymphoid cells and its role in diseases

    • Principal Investigator
      生田 宏一
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Kyoto University
  •  Glucocorticoids enhance the differentiation and function of Th17 cells and cause colitisPrincipal Investigator

    • Principal Investigator
      Shimba Akihiro
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Kyoto University

All 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] Pleiotropic Effects of Glucocorticoids on the Immune System in Circadian Rhythm and Stress2021

    • Author(s)
      Akihiro Shimba, Aki Ejima, Koichi Ikuta
    • Journal Title

      Front Immunol

      Volume: 706951

    • DOI

      10.3389/fimmu.2021.706951

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16280
  • [Journal Article] Glucocorticoids Regulate Circadian Rhythm of Innate and Adaptive Immunity2020

    • Author(s)
      Shimba A. and Ikuta K.
    • Journal Title

      Frontiers in Immunology

      Volume: 11 Pages: 2143-2143

    • DOI

      10.3389/fimmu.2020.02143

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K16280
  • [Journal Article] Immune-enhancing effects of glucocorticoids in response to day?night cycles and stress2020

    • Author(s)
      Shimba A. and Ikuta K.
    • Journal Title

      International Immunology

      Volume: 32 Pages: 703-708

    • DOI

      10.1093/intimm/dxaa048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K16280
  • [Journal Article] Acceleration of immune senescence-mediated ageing process by long-term circadian misalignment.2020

    • Author(s)
      Inokawa Hitoshi, Umemura Yasuhiro, Shimba Akihiro, Kawakami Eiryo, Koike Nobuya, Tsuchiya Yoshiki, Ohashi Munehiro, Minami Yoichi, Cui Guangwei, Asahi Takuma, Ono Ryutaro, Sasawaki Yuh, Konishi Eiichi, Yoo Seung-Hee, Chen Zheng, Teramukai Satoshi, Ikuta Koichi, Yagita Kazuhiro
    • Journal Title

      Sci Rep

      Volume: 10 Pages: 2569-2569

    • DOI

      10.1038/s41598-020-59541-y

    • NAID

      120006799241

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600, KAKENHI-PROJECT-17K11021, KAKENHI-PROJECT-17KT0129, KAKENHI-PROJECT-18K15184
  • [Journal Article] Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intraepithelial lymphocytes in the intestine.2020

    • Author(s)
      Zhu Yuanbo、Cui Guangwei、Miyauchi Eiji、Nakanishi Yuki、Mukohira Hisa、Shimba Akihiro、Abe Shinya、Tani-ichi Shizue、Hara Takahiro、Nakase Hiroshi、Chiba Tsutomu、Sehara-Fujisawa Atsuko、Seno Hiroshi、Ohno Hiroshi、Ikuta Koichi
    • Journal Title

      Int Immunol

      Volume: 32 Pages: 307-319

    • DOI

      10.1093/intimm/dxz082

    • NAID

      120006846480

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-19K07604, KAKENHI-PROJECT-19K16687, KAKENHI-PROJECT-19K16712, KAKENHI-PROJECT-20K16280, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-18K07958
  • [Journal Article] Control of immunity by glucocorticoids in health and disease2020

    • Author(s)
      Shimba A. and Ikuta K.
    • Journal Title

      Seminars in Immunopathology

      Volume: 42 Pages: 669-680

    • DOI

      10.1007/s00281-020-00827-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K16280
  • [Presentation] 胎児肝臓に由来する1型自然リンパ球の同定2021

    • Author(s)
      旭拓真、阿部真也、崔広為、榛葉旭恒、生田宏一
    • Organizer
      Kyoto T Cell Conference 第30回学術集会
    • Data Source
      KAKENHI-PROJECT-20K21525
  • [Presentation] ステロイドホルモンによる免疫機能とアレルギーの制御2021

    • Author(s)
      生田宏一、榛葉旭恒、江島亜希
    • Organizer
      日本アレルギー学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03501
  • [Presentation] Control of T cell immunity by glucocorticoids2021

    • Author(s)
      榛葉旭恒、生田宏一
    • Organizer
      第28回日本時間生物学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K16280
  • [Presentation] 胎児肝臓に由来する1型自然リンパ球の同定2021

    • Author(s)
      旭拓真、阿部真也、崔広為、榛葉旭恒、生田宏一
    • Organizer
      Kyoto T Cell Conference 第30回学術集会
    • Data Source
      KAKENHI-PROJECT-20H03501
  • [Presentation] ステロイドホルモンによる免疫機能とアレルギーの制御2021

    • Author(s)
      生田宏一、榛葉旭恒、江島亜希
    • Organizer
      日本アレルギー学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21525
  • [Presentation] ストレスはグルココルチコイドを介してTh17細胞を活性化する2021

    • Author(s)
      榛葉旭恒、生田宏一
    • Organizer
      第30回Kyoto T Cell Conference
    • Data Source
      KAKENHI-PROJECT-20K16280
  • [Presentation] ストレスはグルココルチコイドを介してTh17細胞の分化を促進し腸炎を増悪させる2021

    • Author(s)
      榛葉旭恒、生田宏一
    • Organizer
      Kyoto T Cell Conference 第30回学術集会
    • Data Source
      KAKENHI-PROJECT-20H03501
  • [Presentation] ストレスはグルココルチコイドを介してTh17細胞の分化を促進し腸炎を増悪させる2021

    • Author(s)
      榛葉旭恒、生田宏一
    • Organizer
      Kyoto T Cell Conference 第30回学術集会
    • Data Source
      KAKENHI-PROJECT-20K21525
  • [Presentation] Control of immunity by glucocorticoids2019

    • Author(s)
      Shimba Akihiro
    • Organizer
      第48回日本免疫学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K15184
  • [Presentation] Glucocorticoids enhance T cell immune response.2019

    • Author(s)
      榛葉旭恒
    • Organizer
      日本免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K15184
  • 1.  生田 宏一 (90193177)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 2.  崔 广為 (70791276)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  谷一 靖江 (50432331)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  UMEMURA Yasuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  HARA Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  八木田 和弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  南 陽一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  宮内 栄治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  中西 祐貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  千葉 勉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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