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Ito Shin  伊藤 慎

ORCIDConnect your ORCID iD *help
Researcher Number 20796560
Affiliation (Current) 2025: 国立研究開発法人国立循環器病研究センター, 病院, 室長
Affiliation (based on the past Project Information) *help 2019 – 2024: 国立研究開発法人国立循環器病研究センター, 病院, 室長
2018: 国立研究開発法人国立循環器病研究センター, 臨床研究開発部, 室長
Review Section/Research Field
Principal Investigator
Basic Section 53020:Cardiology-related
Except Principal Investigator
Basic Section 53020:Cardiology-related
Keywords
Principal Investigator
遺伝子解析 / 遺伝子変異 / 心不全 / スプライシング / 心肥大
Except Principal Investigator
心不全 / SVEP1 / 細胞外マトリックス / トランスレーショナル研究 / 心筋症
  • Research Projects

    (4 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (11 People)
  •  Elucidation of the roles of a new extracellular matrix protein SVEP1 in the pathogenesis of heart failure

    • Principal Investigator
      坂田 泰彦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  遠隔虚血コンディショニングによる心不全発症・進展抑止効果とそのメカニズムの検討

    • Principal Investigator
      浅沼 博司
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Meiji University of Integrative Medicine
  •  Development of new treatments for cardiomyopathy and heart failure targeting mechanosensor channels

    • Principal Investigator
      Iwata Yuko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Elucidation of the mechanism of cardiac hypertrophy suppression by Mtus1 gene and its clinical applicationPrincipal Investigator

    • Principal Investigator
      Ito Shin
    • Project Period (FY)
      2018 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      National Cardiovascular Center Research Institute

All 2022 2020 2019

All Journal Article Presentation

  • [Journal Article] Tranilast for advanced heart failure in patients with muscular dystrophy: a single-arm, open-label, multicenter study2022

    • Author(s)
      Matsumura Tsuyoshi、Hashimoto Hiroya、Sekimizu Masahiro、Saito Akiko M.、Motoyoshi Yasufumi、Nakamura Akinori、Kuru Satoshi、Fukudome Takayasu、Segawa Kazuhiko、Takahashi Toshiaki、Tamura Takuhisa、Komori Tetsuo、Watanabe Chigusa、Asakura Masanori、Kimura Koichi、Iwata Yuko
    • Journal Title

      Orphanet Journal of Rare Diseases

      Volume: 17 Issue: 1

    • DOI

      10.1186/s13023-022-02352-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08462
  • [Journal Article] Production of TRPV2-targeting functional antibody ameliorating dilated cardiomyopathy and muscular dystrophy in animal models2020

    • Author(s)
      Iwata Yuko、Wakabayashi Shigeo、Ito Shin、Kitakaze Masafumi
    • Journal Title

      Laboratory Investigation

      Volume: 100 Issue: 2 Pages: 324-337

    • DOI

      10.1038/s41374-019-0363-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09598, KAKENHI-PROJECT-20K08462
  • [Journal Article] Study Protocol for a Multicenter, Open-Label, Single-Arm Study of Tranilast for Cardiomyopathy of Muscular Dystrophy2019

    • Author(s)
      MATSUMURA TSUYOSHI、HASHIMOTO HIROYA、SEKIMIZU MASAHIRO、SAITO AKIKO M.、IWATA YUKO、ASAKURA MASANORI、KIMURA KOICHI、TAMURA TAKUHISA、FUNATO MICHINORI、SEGAWA KAZUHIKO、OGATA KATSUHISA、NAKAJIMA TAKASHI
    • Journal Title

      The Kurume Medical Journal

      Volume: 66 Issue: 2 Pages: 121-126

    • DOI

      10.2739/kurumemedj.MS662006

    • NAID

      130008066540

    • ISSN
      0023-5679, 1881-2090
    • Year and Date
      2019-06-30
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08462
  • [Presentation] A single-arm, open-label, multicenter study of tranilast for advanced heart failure in patients with muscular dystrophy2022

    • Author(s)
      MATSUMURA TSUYOSHI、HASHIMOTO HIROYA、SEKIMIZU MASAHIRO、SAITO AKIKO M.、IWATA YUKO、ASAKURA MASANORI、KIMURA KOICHI、TAMURA TAKUHISA、FUNATO MICHINORI、SEGAWA KAZUHIKO、OGATA KATSUHISA、NAKAJIMA TAKASHI
    • Organizer
      World Muscle Society 2022
    • Data Source
      KAKENHI-PROJECT-20K08462
  • [Presentation] TRPV2 channel as a promising therapeutic target for heart failure2020

    • Author(s)
      Iwata Y, Wakabayashi S, Ito S, Kitakaze M
    • Organizer
      International Symposium on TRP Ion Channel at Wakayama
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08462
  • [Presentation] 心筋症モデル動物の病態を改善するCa2+透過チャネルTRPV2の機能的抗体の作成2020

    • Author(s)
      岩田裕子、若林繁夫、伊藤慎、北風政史
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K08462
  • [Presentation] Alternative splicing of Mtus1 mRNA affects cardiac hypertrophy and heart failure2019

    • Author(s)
      伊藤 慎
    • Organizer
      第36回 国際心臓研究学会日本部会
    • Data Source
      KAKENHI-PROJECT-18K15873
  • 1.  Iwata Yuko (80171908)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 2.  泉 知里 (70768100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  浅沼 博司 (20416217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  新谷 泰範 (20712243)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  坂田 泰彦 (90379206)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  富松 航佑 (00614926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  北井 豪 (10470204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  菊地 和 (10638240)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  竹田 浩之 (40609393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  畠山 金太 (60325735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  長崎 正朗 (90396862)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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