Takayama Koichiro 高山幸一郎

Researcher Number	20816988
Other IDs	https://orcid.org/0000-0003-4670-7063
Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, オープンイノベーションセンター, 客員研究員
Affiliation (based on the past Project Information) *help	2024: 国立研究開発法人国立循環器病研究センター, オープンイノベーションセンター, 客員研究員 2022: 国立研究開発法人国立循環器病研究センター, 分子生物学部, 非常勤研究員 2021: 国立研究開発法人国立循環器病研究センター, 分子生物学部, リサーチフェロー 2021: 国立研究開発法人国立循環器病研究センター, 研究所, リサーチフェロー 2019 – 2020: 国立研究開発法人国立循環器病研究センター, 研究所, 流動研究員
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 疾患モデルiPS細胞 / 一過性外向きカリウム電流 / KCND3変異 / 早期再分極症候群 / イオンチャネル病 / 難治性てんかん / 電気生理学的機能解析 / iPS細胞由来心筋細胞 / 心筋イオンチャネルの遺伝子変異 / 若年性心臓突然死 / ベプリジル / キニジン / 機能獲得型障害 … More Except Principal Investigator … More DNA構造多型 / DNA構造異常 / long read sequencer / ゲノム構造多型 / ゲノムDNA構造異常 / 遺伝性不整脈 Less

疾患モデルiPS細胞を用いたKCND3変異による早期再分極症候群の病態解明Principal Investigator
- Principal Investigator
  
  高山幸一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
The elucidation of complicated genetic backgrounds and pathogenicity in patients with inherited primary arrhythmia syndromes caused by unknown etiology
- Principal Investigator
  
  大野聖子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Cardiovascular Center Research Institute
Electrophysiological analysis of pathogenesis and effective therapy for early repolarization syndromePrincipal Investigator
- Principal Investigator
  
  Takayama Koichiro
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute

All 2022 2021 2019

All Journal Article Presentation

[Journal Article] Impact of cascade screening for catecholaminergic polymorphic ventricular tachycardia type 12022
- Author(s)
  Shimamoto K, Ohno S, Kato K, Takayama K, Sonoda K, Fukuyama M, Makiyama T, Okamura S, Asakura K, Imanishi N, Kato Y, Sakaguchi H, Kamakura T, Wada M, Yamagata K, Ishibashi K, Inoue Y, Miyamoto K, Nagase S, Kusano K, Horie M, Aiba T.
- Journal Title
  
  Heart
  
  Volume: - Issue: 11 Pages: 2021-320220
- DOI
  10.1136/heartjnl-2021-320220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08538, KAKENHI-PROJECT-19K08555, KAKENHI-PROJECT-21H02888, KAKENHI-PROJECT-21K07765, KAKENHI-PROJECT-19K08505, KAKENHI-PROJECT-19K17581
[Journal Article] A de novo gain-of-function KCND3 mutation in early repolarization syndrome2019
- Author(s)
  Takayama Koichiro、Ohno Seiko、Ding Wei-Guang、Ashihara Takashi、Fukumoto Daisuke、Wada Yuko、Makiyama Takeru、Kise Hiroaki、Hoshiai Minako、Matsuura Hiroshi、Horie Minoru
- Journal Title
  
  Heart Rhythm
  
  Volume: 16 Issue: 11 Pages: 1698-1706
- DOI
  10.1016/j.hrthm.2019.05.033
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-19K08538, KAKENHI-PROJECT-19K17593, KAKENHI-PROJECT-17K08536, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18H02808
[Presentation] Bepridil is Effective to Restore the Slow Inactivation in Mutant Kv4.3 Channel Identified in an Early Repolarization Syndrome Patient2021
- Author(s)
  Koichiro Takayama
- Organizer
  第67回日本不整脈心電学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16102
[Presentation] Low Dose of Quinidine is Effective to Normalize the Slow Inactivation in Mutant Kv4.3 Channel Identified in an Early Repolarization Syndrome Patient2019
- Author(s)
  Koichiro Takayama, Wei-Guang Ding, Hiroshi Matsuura, Minoru Horie, Seiko Ohno
- Organizer
  欧州心臓病学会（ESC）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17593

1. 大野聖子 (20610025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. ZANKOV DimitarP (20631295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 牧山武 (30528302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 相庭武司 (40574348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 福山恵 (60625771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 加藤浩一 (70736983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 園田桂子 (90824417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Wang Qi (70756767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Takayama Koichiro 高山幸一郎

Research Projects

Research Products

Co-Researchers

疾患モデルiPS細胞を用いたKCND3変異による早期再分極症候群の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of complicated genetic backgrounds and pathogenicity in patients with inherited primary arrhythmia syndromes caused by unknown etiology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Electrophysiological analysis of pathogenesis and effective therapy for early repolarization syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Impact of cascade screening for catecholaminergic polymorphic ventricular tachycardia type 12022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A de novo gain-of-function KCND3 mutation in early repolarization syndrome2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Bepridil is Effective to Restore the Slow Inactivation in Mutant Kv4.3 Channel Identified in an Early Repolarization Syndrome Patient2021

Author(s)

Organizer

Data Source

[Presentation] Low Dose of Quinidine is Effective to Normalize the Slow Inactivation in Mutant Kv4.3 Channel Identified in an Early Repolarization Syndrome Patient2019

Author(s)

Organizer

Data Source

Takayama Koichiro 高山 幸一郎

Research Projects

Research Products

Co-Researchers

疾患モデルiPS細胞を用いたKCND3変異による早期再分極症候群の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of complicated genetic backgrounds and pathogenicity in patients with inherited primary arrhythmia syndromes caused by unknown etiology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Electrophysiological analysis of pathogenesis and effective therapy for early repolarization syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Impact of cascade screening for catecholaminergic polymorphic ventricular tachycardia type 12022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A de novo gain-of-function KCND3 mutation in early repolarization syndrome2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Bepridil is Effective to Restore the Slow Inactivation in Mutant Kv4.3 Channel Identified in an Early Repolarization Syndrome Patient2021

Author(s)

Organizer

Data Source

[Presentation] Low Dose of Quinidine is Effective to Normalize the Slow Inactivation in Mutant Kv4.3 Channel Identified in an Early Repolarization Syndrome Patient2019

Author(s)

Organizer

Data Source

Takayama Koichiro 高山幸一郎