Kuromi Hiroshi 黒見坦

… Alternative Names

黒見坦クロミヒロシ

黒見担クロミヒロシ

KUROMI Hiroshi 黒見坦

黒海坦クロミヒロシ

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Researcher Number	30009633
Affiliation (Current)	2025: 公益財団法人東京都医学総合研究所, 脳・神経科学研究分野, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 公益財団法人東京都医学総合研究所, 脳・神経科学研究分野, 研究員 2008 – 2009: いわき明星大学, 薬学部, 教授 2007: Gunma University, Graduate School of Medicine, associate professor 2006: 群馬大学, 大学院医学系研究科, 助教授 2004 – 2005: 群馬大学, 大学院・医学系研究科, 助教授 … More 1998 – 2000: 群馬大学, 医学部, 助教授 1995: Gunma University School of Medicine, Associate Professor, 医学部, 助教授 1994: 千葉大学, 医学部, 助教授 1992 – 1993: 千葉大学, 医学部, 講師 1987 – 1990: 千葉大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Neurophysiology and muscle physiology / 神経・脳内生理学 Except Principal Investigator 内分泌・代謝学 / General pharmacology / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Neurochemistry/Neuropharmacology / 神経・脳内生理学
Keywords	Principal Investigator active-zone / endocytosis / La3+ / synaptic vesicles / シナプス小胞 / シナプス伝達 / ショウジョウバエ / synaptic transmission / exocytosis / ノンアクチブゾーン … More / アクチブゾーン / エキソサイトシス / エンドサイトシス / リサイクル / rutabaga / dunce / reserve pool / endo cycling pool / exo / FM1-43 / synaptic vesicle / Ca2+チャネル / non-active zone / recycle / drosonhila / synapse / チュブリン / non-actve zone / 神経終末 / channel / drosophila / recycling / タンパクリン酸化 / PLTXII / 高頻度刺激 / チャネル / PKA cascade / cAMP / stimulation frequency / cyclosporin A / forskolin / quantal content / cytochalasin D / high rate stimulation / low rate stimulation / Ca^<2+>チャネル / Ca^<2+>イメージング / 神経筋シナプス / リザーブプール / 小胞リサイクル / 小胞エンドサイトシス / シナプス可塑性 / 運動神経一筋接合部 / ニューロン・シナプス機能 … More Except Principal Investigator ショウジョウバエ / インスリン / カルシウム / SNAREs / Drosophila / シナプス小胞 / ion channels / インスリン非依存性糖尿病 / スルホニール尿素剤 / 糖尿病 / イオンチャネル / 遺伝子 / G蛋白質 / セロトニン作動性神経細胞 / セロトニン作動性神経 / 情動伝染 / mouse / chick / adhesion / skeletal muscle / development / smooth muscle / sympathetic innervation / 骨格筋 / Geographutoxin / 自律神経 / 平滑筋 / シナプス形成 / 内向き整流Kチャンネル / Naチャンネル / Caチャンネル / 発達 / マウス骨格筋 / Synaptic vesicle / complexin / Synaphin / Neurotransmitter release / シナプス小脳 / コンプレキシン / シナーフィン / 神経伝達物質放出 / synaptic vesicle pools / vesicle recycling / neuromuscular junctions / shibire / synaptic transmission / mutants / Cultered neurons / 小胞リサイクリング / シナプス電流 / 膜電位固定法 / 神経培養 / シナプス / 突然変異体 / G-protein coupled receptor / Sulfonylureas / Genes / Ion channels / Insulin / Diabetes / G蛋白質共役受容体 / カルシウムシグナル / 遺伝子変異 / K^+チャネル / G蛋白共役受容体 / insulin / sulfonylurea / potassium / calcium / Diabetes mellitus / gene / イオンチャネルグルタミン酸受容体 / カルシウムチャネル遺伝子 / カリウム / Receptor-imaging / Somatostatin Analogs / Tumors / G-protein / Somatostatin Receptors / ソマトスタチンアナログ / 画像診断 / 腫瘍 / ソマトスタチン受容体 / 細胞毒性 / 細胞死 / 初代培養 / 神経細胞 / 分化誘導因子 / 細胞性粘菌 / Bax / Bcl2 / グルタミン酸 / アポトーシス / シナプトタグミン / 小胞関連蛋白質 / 分泌小胞 / 低分子量G蛋白質 / 開口放出 / エクソサイトーシス / Kー252a / 神経成長因子 / 培養神経細胞 / リンパ細胞 / 神経栄養因子 Less

A pair of 5-HT neurons responsible for emotional contagion in Drosophila
- Principal Investigator
  
  齊藤実
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Plastic changes associated with spontaneous motor activity at neuromuscular junction.Principal Investigator
- Principal Investigator
  
  KUROMI Hiroshi, KIDOKORO Yoshiaki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Gunma University
Study of mechanism for synaptic vesicle recyclingPrincipal Investigator
- Principal Investigator
  
  KUROMI Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Gunma University
Synaptic vesicle recycling and changes in synaptic efficacyPrincipal Investigator
- Principal Investigator
  
  KUROMI Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Gunma University
Dynamic behavior of the proteins involved in the synaptic vesicle cycle
- Principal Investigator
  
  ABE Teruo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Niigata University
樹状突起スパインの神経防御機能の検証
- Principal Investigator
  
  林謙介
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gunma University
Drosophila Neuromuscular Junction Formation in Culture
- Principal Investigator
  
  KIDOKORO Yoshiaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  神経・脳内生理学
- Research Institution
  Gunma University School of Medicine
Synaptic vesicle pools and vesicle recycling in nerve terminalsPrincipal Investigator
- Principal Investigator
  
  KUROMI Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Gunma University, School of Medicine, Institute for Behavioral Science
グルタミン酸受容体を発現した細胞株における細胞内情報伝達の分子機構
- Principal Investigator
  
  清野進
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
低分子量G蛋白質とその標的蛋白質のインスリン分泌における意義
- Principal Investigator
  
  清野進
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Molecular Biology and Genetics of Ion Channels in beta-cells : their roles in diabetes mellitus.
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Studies on the genes susceptible to non-insulin dependent diabetes mellitus in Japanese.
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University School of Medicine
インスリン分泌とその異常におけるRab蛋白の役割
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Development of various somatostatin analogs for the treatment and diagnosis of tumors utilizing somatostatin receptor genes
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University
膵臓細胞の産生する培養ニュ-ロンの生存を促進する因子
- Principal Investigator
  
  HASEGAWA Shuji
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Chiba University
Molecular bases of sympathetic innervation and developmental changes in ion channels
- Principal Investigator
  
  HASEGAWA Shuji, 萩原彌四郎
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Chiba University

All 2023 2010 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] Encyclopedia References of Neuroscience.2008
- Author(s)
  Kuromi H.
- Publisher
  Synaptic vesicle recycling.
- Data Source
  KAKENHI-PROJECT-19300140
[Journal Article] A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia2023
- Author(s)
  Suzuki Mari、Kuromi Hiroshi、Shindo Mayumi、Sakata Nozomi、Niimi Naoko、Fukui Koji、Saitoe Minoru、Sango Kazunori
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 6 Pages: 106997-106997
- DOI
  10.1016/j.isci.2023.106997
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18238, KAKENHI-PROJECT-19H01013
[Journal Article] Two types of Ca2+ channel linked to two endocytic pathways coordinately maintain synaptic transmission at the Drosophila synapse.2010
- Author(s)
  Kuromi,H., Ueno,K., Kidokoro,Y.
- Journal Title
  
  Europ.J.Neurosci 32
  
  Pages: 335-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300140
[Journal Article] 2^<nd> author.Bicaudal-D binds clathrin heavy chain to promote its transport and augments synaptic vesicle recycling.2010
- Author(s)
  Xuan L., Kuromi H, et al. 7名
- Journal Title
  
  EMBO J. 29
  
  Pages: 992-10006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300140
[Journal Article] Synaptic vesicle recycling2008
- Author(s)
  Kuromi, H.
- Journal Title
  
  Encyclopedia References of Neuroscience
  
  Pages: 2420-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300131
[Journal Article] Experience-dependent formation and recruitment of large vesicles from reserve pool.2006
- Author(s)
  Steinert, JR, Kuromi H. et al.
- Journal Title
  
  Neuron 50
  
  Pages: 723-733
- Data Source
  KAKENHI-PROJECT-18300131
[Journal Article] Experience-dependent formation and recruitment of large vesicles from reserve pool2006
- Author(s)
  Steinert Y., Kuromi,H., et. al.
- Journal Title
  
  Neuron 50
  
  Pages: 723-733
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300131
[Journal Article] Experinence-dependent formation and recruitment of large vesicles from reserve pool2006
- Author(s)
  Steinert, Y. Kuromi, H. et. al.
- Journal Title
  
  Neuron 50
  
  Pages: 723-733
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300131
[Journal Article] Exocytosis and endocytosis of synaptic vesicles and functional roles of synaptic vesicle pools lessons from the Drosophila neuromuscular junction2005
- Author(s)
  H.Kuromi, Y.Kidokoro
- Journal Title
  
  Neuroscientist 11(2)
  
  Pages: 138-147
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500238
[Journal Article] Analysis of conditional paralytic mutants in Drosophila sarco-endoplasmic reticulum calcium ATPase2005
- Author(s)
  Sanyal, S., Consoulas, C., Kuromi, H.et al.
- Journal Title
  
  Genetics 169
  
  Pages: 737-750
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Exocytosis and endocytosis of synaptic vesicles and functional roles of synaptic vesicle pools: lessons form the Drosophila neuromuscular junction2005
- Author(s)
  H.Kuromi, Y.Kidokoro
- Journal Title
  
  Neuroscientist 11(2)
  
  Pages: 138-147
- Data Source
  KAKENHI-PROJECT-16500238
[Journal Article] Exocytosis and endocytosis of synaptic vesicles and functional roles of synaptic vesicle pools : lessons from the Drosophila neuromuscular junction.2005
- Author(s)
  H.Kuromi, Y.Kidokoro
- Journal Title
  
  Neuroscientist 11(2)
  
  Pages: 138-147
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500238
[Journal Article] Exocytosis and endocytosis of synaptic vesicles and functional roles of synaptic vesicle pools : lessons from the Drosophila neuromuscular junction2005
- Author(s)
  H.Kuromi, Y.Kidokoro
- Journal Title
  
  Neuroscientist 11(2)
  
  Pages: 138-147
- Data Source
  KAKENHI-PROJECT-16500238
[Journal Article] Exoxytosis and endocytosis of synaptic vesicles and functional roles of vesicle pools; lesson from the Drosophila neuromuscular junction.2005
- Author(s)
  Kuromi, H.
- Journal Title
  
  The Neuroscientist 11
  
  Pages: 138-147
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Exocytosis and endocytosis of synaptic vesicles and functional roles of vesicle pools ; lesson from the Drosophila neuromuscular junction2005
- Author(s)
  kuromi, H., Kidokoro, Y.
- Journal Title
  
  Neuroscientist 11
  
  Pages: 138-147
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Exocytosis and endocytosis of synaptic veicles and functional roles of vesicle pools ; lesson from the Drosophila neuromuscular junctions2005
- Author(s)
  Kuromi, H.
- Journal Title
  
  Neuroscientist 11
  
  Pages: 138-147
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Repetitive exposures to nicotin induce a hyperresponsiveness via the cAMP/PKA/CREB signal pathway in Drosophila2004
- Author(s)
  Hou, J., Kuromi H, et al.
- Journal Title
  
  J.Neurobil. 60
  
  Pages: 249-261
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Ca2+ influx through distinct routs controls exocytosis and endocytosis at Drospophila presynaptic terminals.2004
- Author(s)
  Kuromi, H.
- Journal Title
  
  Neuron 41
  
  Pages: 101-111
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Ca2+ influx through distinct routs controls exocytosis and endocytosis at Drosophila presynaptic terminal.2004
- Author(s)
  Kuromi, H.
- Journal Title
  
  Neuron 41
  
  Pages: 101-111
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Ca2+ influx through distinct routs controls exocytosis and endocytosis at Droshophila presynantic terminals2004
- Author(s)
  Kuromi, H., Honda, A., Kidokoro, Y.
- Journal Title
  
  Neuron 41
  
  Pages: 101-111
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Synaptic vesicle pools, and plasticity of synaptic transmission at the Drosophila synapse2004
- Author(s)
  Kidokoro, Y., Kuromi H., et al.
- Journal Title
  
  Brain Res.Rev. 47
  
  Pages: 18-32
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Synaptic vesicle recycling
- Author(s)
  Kuromi, H.
- Journal Title
  
  Encyclopedias (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Synaptic vesicle recycling
- Author(s)
  Kuromi, H.
- Journal Title
  
  Excyclopedia References of Neurosciences (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300131
[Journal Article] Analysis of conditional paralytic mutants in drosophila SERCA reveals novel mechanisms for regulating membrane excitability
- Author(s)
  Sanyal, s., Consoulas C, Kuromi H., et al.
- Journal Title
  
  Genetics (in press)
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Synaptic vesicle recycling.
- Author(s)
  Kuromi, H.
- Journal Title
  
  Encyclopedias (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300130
[Journal Article] Synaptic vesicle recycling
- Author(s)
  Kuromi,H.
- Journal Title
  
  Encyclopedia reference of Neurosciences (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300131
[Presentation] A subset of 5HT neurons integrates sensory information to induce emotional contagion in Drosophila.2023
- Author(s)
  Maximiliano Martinez-Cordera, Minoru Saitoe, Hiroshi Kuromi
- Organizer
  第46回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18238
[Presentation] Drosophila visually evokes aversive contagion by a subset of serotonergic neurons.2023
- Author(s)
  Maximiliano Martinez-Cordera, Hiroshi Kuromi, Kohei Ueno, Minoru Saitoe
- Organizer
  記憶研究会２０２３
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18238
[Presentation] シナプス小胞リサイクルにおけるNa/K ATPase の役割2008
- Author(s)
  黒見坦、上野耕平、城所義明
- Organizer
  31回日本神経科学大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19300140
[Presentation] Roles of Na/K ATPase in synaptic vesicle recycling2008
- Author(s)
  Kuromi, H., Ueno K. and Kidokoro, Y.
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19300140
[Presentation] Two distinct pathways for endocytosis and synaptic transmission at the drosophila neuromuscular junction.2007
- Author(s)
  黒見坦, 上野耕平, 城所義明
- Organizer
  Neuroscience 2007
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19300140
[Presentation] Two distinct pathways for endocytosis and synaptic transmission at the Drosophila neuromuscular junction.2007
- Author(s)
  Kuromi, H. et. a.l
- Organizer
  Neuroscience2007
- Place of Presentation
  San Diego
- Year and Date
  2007-11-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300131
[Presentation] Two distinct pathways for Endocytosis and synaptic transmission at the Drosophila neuromuscular junction2007
- Author(s)
  Kuromi,H., Ueno,K. and Kidokoro, Y.
- Organizer
  Neurosci2007
- Place of Presentation
  San Diego, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300131

1. SEINO Susumu (80236067)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. GONOI Tohru (30134365)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. INAGAKI Nobuya (30241954)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. UENO Kouhei (40332556)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
5. HASEGAWA Shuji (20009640)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KIDOKORO Yoshiaki (00053083)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
7. MAKINO Eiichi (50009578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIHARA Motojiro (80222397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ABE Teruo (50010103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 林謙介 (50218567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 萩原彌四郎 (10009079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 齊藤実 (50261839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 鈴木力憲 (80836172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. HAYASHI Shigehiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TOKUYAMA Yoshiharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. STOFFEL Markus

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. POLONSKY Kenneth S.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. BLONDEL Oliv

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. BLONDE Olivier

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 齋藤実

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Kuromi Hiroshi 黒見 坦

黒見 坦 クロミ ヒロシ

黒見 担 クロミ ヒロシ

KUROMI Hiroshi 黒見 坦

黒海 坦 クロミ ヒロシ

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Plastic changes associated with spontaneous motor activity at neuromuscular junction.Principal Investigator

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Study of mechanism for synaptic vesicle recyclingPrincipal Investigator

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Synaptic vesicle recycling and changes in synaptic efficacyPrincipal Investigator

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Synaptic vesicle pools and vesicle recycling in nerve terminalsPrincipal Investigator

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Kuromi Hiroshi 黒見坦

黒見坦クロミヒロシ

黒見担クロミヒロシ

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