GOTO Katsutoshi 後藤勝年

… Alternative Names

和藤勝年ゴトウカツトシ

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Researcher Number	30012660
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2006: 筑波大学, 名誉教授 2004 – 2005: 筑波大学, 大学院・人間総合科学研究科, 教授 1990 – 2003: 筑波大学, 基礎医学系, 教授 2002: 筑波大, 基礎医学系, 教授 1997: 筑波大学, 臨床医学系, 教授 1987 – 1989: 筑波大学, 基礎医学系, 助教授 1986: 筑大, 基礎医学系, 助教授
Review Section/Research Field	Principal Investigator General pharmacology / 応用薬理学・医療系薬学 Except Principal Investigator General pharmacology / Circulatory organs internal medicine / General pharmacology / 応用薬理学・医療系薬学 / Bioproduction chemistry/Bioorganic chemistry / Biological Sciences / 血管生物学
Keywords	Principal Investigator エンドセリン / CGRP / HIF-1α / カプサイシン / エンドセリン受容体 / SB209670 / mesenteric artery / 冠血管 / 知覚神経 / 腸管膜動脈 … More / ナルコレプシー / 摂食行動 / オレキシン / coronary artery / cardiac muscle / Adenylate cyclase / CGRP-receptors / CGRP (Calcitonin gene-related peptide) / Nonadrenergic noncholinergic nerve / 神経ペプチド / アデニルシクラーゼ / 陽性変時変力作用 / 非アドレナリン非コリン作動性(NANC)神経 / 内皮細胞 / 脳底動脈 / 冠動脈 / サイクリックAMP / 血管拡張神経内皮細胞 / 心房筋 / アデニレートシクラーゼ / CGRP受容体 / カルシトニン遺伝子関連ペプチド(CGRP) / 非アドレナリン非コリン作動性神経 / Behavioral analysis / Neuronal network / Slice patch clamp / Knockout mice / Transgenic mice / Feeding behavior / Sleep and wakefulness / Orexin / 抗体 / カタプレキシー / 脳室内投与 / 遺伝子改変マウス / パッチクランプ / アセチルコリン / セロトニン / 睡眠 / 免疫染色 / GFP / 破傷風毒素 / コレシストキニン / イメージング / カルシウム / カルシウム感受性タンパク質 / 行動解析 / 神経回路 / スライスパッチクランプ / ノックアウトマウス / トランスジェニックマウス / 睡眠覚醒 / ET receptor antagonist / cardiomyopathic hamster / cardiac remodeling / chronic heart failure / myocardial infarction / chronic circulatory disease / endothelin / 免疫組織化学 / 変換酵素 / 心筋梗塞ラット / upregulation / 動脈硬化 / ミトコンドリア / アポトーシス / 受容体拮抗薬 / 受容体 / 心不全 / 心筋症ハムスター / ET受容体拮抗薬 / リモデリング / 慢性心不全 / 心筋梗塞 / 慢性循環器疾患 / capsaicin / CO2 / sensory nerve / askeletal muscle / hindlimb / regional blood flow / ラット / EDHF / 血管弛緩 / 血流 / 二酸化炭素 / カルシトニン遺伝子関連ペプチド / CO2分圧 / 骨格筋運動 / ラット後肢 / 局所血流 / Astrocytes / ET_B receptor / Endothelin / cold injury / 増殖因子 / 脳抽出液 / 中枢神経系 / アンタゴニスト / 脊髄損傷 / 凍結損傷 / アストロサイト / ET_B受容体 / endothelin-1 / microcirculation / heart / endothelium / hypertension / vasodilation / 代謝性血流調筋 / 心筋 / 血中濃度 / CGRP拮抗薬 / 求心性知覚神経 / 座骨神経 / postーtetanic hyperemia / 骨格筋 / 心臓 / 血管内皮細胞 / 骨格筋強縮 / 血流増加反応 / 骨格筋収縮 / 微小循環系 / 高血圧と加齢 / 血管拡張神経 / OX2受容体 / OXI受容体 / 覚醒 / ox2受容体 / ox1受容体 … More Except Principal Investigator エンドセリン / endothelin / 心不全 / 薬理学 / 心肥大 / エンドセリン拮抗薬 / 分子生物学 / orexin / レプチン / オレキシン / endothelin antagonist / heart failure / 循環器疾患 / 神経ペプチド / NPY / JAK2 / narcolepsy / feeding / leptin / ナルコレプシー / 睡眠 / 覚醒 / 摂食行動 / グレリン / gene expression / 遺伝子発現 / molecular pharmacology / 分子薬理学 / pharmacology / molecular biology / エンドセリン受容体遮断薬 / 病態生理学 / 循環薬理学 / サイトカイン / Endothelin / カルシュウムチャンネル / 血管収縮 / 内皮細胞 / 血圧 / TNF-alfa / hypothalamus / STAT-3 / JAK2キナーゼ / K-ATPチャンネル / PI3キナーゼ / PI3K / TNF-α / 視床下部 / endothelin blocker / fenofibrate / transcription / cardiovascular disease / 脂肪代謝 / AP-1 / フェノフィブレート / PPAR-α / 高血圧 / 心筋リモデリング / トレッドミル / 運動耐容能 / エンドセリン遮断薬 / フェノフィプレート / 転写調節 / adaptive behavior / serotonin / acetylcholine / arousal / エネルギーバランス / グルコース / 適応行動 / セロトニン / アセチルコリン / obesity / sleep / wakefulness / ghrelin / OX2受容体 / OX1受容体 / 肥満 / cardiac hypeitrsphy / mclesular biology / phtsiology / antagonist / heart failare / 病状悪化 / エネルギー代謝 / 分子循環器学 / 細胞内情報伝達系 / 生理薬理学 / 拮抗薬 / failing heart / cardrovascular substances / cardioprotection / energy metabolism disturbance / 心筋細胞 / 分子循環器病学 / 心臓血管作動性物質 / 不全心筋 / 心血管作動性物質 / 心筋保護 / エネルギー代謝異常 / agricultural chemical / herbicide / apnea / seizure / coma / poisoning / glofosinate / 農薬 / 除草剤 / 呼吸停止 / けいれん / 昏睡 / 中毒 / グルホシネート / pulmonary hypertension / cardiovascular diseases / 新治療法 / エンドセリレ拮抗薬 / 肺高血圧 / pathophysiology / cardiovascular pharmacology / cardiac hypertrophy / Mass-Spectra / Amino Acid Sequence / Structure-Analysis / Survival Factor / Neurtrophil Activator / Chemokine / Cytokine / Regulatory Peptide / FAB質量分析 / アミノ酸配列分析 / 気管平滑筋弛緩因子 / MALDI-TOF質量分析 / アミノ酸配列決定 / 構造解析 / 細胞生存活性因子 / 好中球活性化因子 / ケモカイン / 新規生体機能調節ペプチド / Vascular endothelium / Cerebrospinal fluid / Immunohistochemistry / Cerebral artery / Cerebral vasospasm / エンザイムイムノアッセイ / 脳血管れん縮 / 血管内皮細胞 / 脳脊髄液 / 免疫組織化学 / 血管れん縮 / 脳血管 / Vasoconstriction / Vasodilation / Blood pressure / 血圧調節 / 血管拡張 / intracellular free calcium ion / endothelin receptor / vasoconstriction / エンドセリンのmRNA / エンドセリンのアイソペプチド / エンドセリンのcDNA / 平滑筋収縮 / 平滑筋収縮機構 / ホスホリパ-ゼのリン酸化 / 細胞内遊離カルシュウム / エンドセリン受容体 / 分解条床核 / 扁桃体 / 情動 / 一酸化窒素 / 血管拡張神経 / 脳動脈 / ANP / EDRF / 動脈硬化 / 平滑筋細胞 / 動脈変化 / 血管攣縮 / 血管生物学 / 収縮弛緩 / 増殖因子 / 血管収縮弛緩 / 血管病変 / 内皮由来生理活性物質 / 平滑筋 / 血管内皮 / big ET / 脳血管攣縮 / 内皮細胞腫瘍 / ET受容体 / ホスホラミドン / 変換酵素 / bigET / アイソフォーム / エンドセリン(ET) Less

扁桃体機能、情動の制御に関わる新規神経ペプチドの検索とその生理作用の解明
- Principal Investigator
  
  桜井武
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Mechanisms and physiological roles of regulation of orexin-producing neurons by leptin and TNF-alfa
- Principal Investigator
  
  SAKURAI Takeshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
Molecular pharmacological study and development of new treatment by investigating endothelin in cardiovascular diseases.
- Principal Investigator
  
  MIYAUCHI Takashi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
The analysis of the mechanisms of sleep/wakefulness and feeding behavior regulated by orexinPrincipal Investigator
- Principal Investigator
  
  GOTO Katsutoshi
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
Study of the mechanisms that regulate the activity of orexin-producing neuron.
- Principal Investigator
  
  SAKURAI Takeshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
摂食行動に関与する新規神経ペプチド、オレキシンの生理作用に関する研究Principal Investigator
- Principal Investigator
  
  後藤勝年
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
Molecntan biological and pharmaco-physiological approach to pathophysiological roles of endothelin-1 in aggrarating heart failure
- Principal Investigator
  
  MIYAUCHI Takashi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Tsukuba
Molecular and Developmental Biological Research on Roles of a novel neuropeptide, Orexin
- Principal Investigator
  
  SAKURAI Takeshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
Exploration of the novel therapeutic methods for the treatment of chronic circulatory diseasesPrincipal Investigator
- Principal Investigator
  
  GOTO Katsutoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  University of Tsukuba
Molecular pharmacological approach to roles of endothelin in heart failure and deverlopmet of new tehrapeuetin strategy
- Principal Investigator
  
  MIYAUCHI Takashi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Tsukuba
エンドセリン拮抗薬を用いた心不全に対する新治療法の開発のための分子薬理学的研究
- Principal Investigator
  
  MIYAUCHI Takashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Tsukuba
The Relationship between Serum Glufosinate Concentration and Severity of Poisoning Caused by the Ingestion of a Herbicide Containing Glufosin
- Principal Investigator
  
  KOYAMA Kanji
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  University of Tsukuba
The role new pepdidergic neuron in autoregulation of regional blood flow.Principal Investigator
- Principal Investigator
  
  GOTO Katsutoshi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
Biochemical Study on Novel Bioregulatory Peptides
- Principal Investigator
  
  GOTO Katsutoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  University of Tsukuba
The study of pathophysiological roles of endothelin in heart failure and cardiac hypertrophy and the development of a new treatment based on these findings
- Principal Investigator
  
  SUGISHITA Yasuro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Tsukuba
Basic research for the development of the new treatment using endothelin receptor antagonists in cardiovascular diseases
- Principal Investigator
  
  SUGISHITA Yasuro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Tsukuba
Analysis of dedifferentiation and growth of glial cells in tissue regeneration process after brain damagePrincipal Investigator
- Principal Investigator
  
  GOTO Katsutoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  University of Tsukuba
血管系の機能および病変の基盤としての内皮平滑筋連関
- Principal Investigator
  
  眞崎知生
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
脳血管収縮の神経および内皮細胞による調節
- Principal Investigator
  
  SAITO Akira
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  University of Tsukuba
Regulation of cardiovascular function by novel peptidergic vasodilator nervesPrincipal Investigator
- Principal Investigator
  
  GOTO Katsutoshi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
Endothelium-derived vasoactive peptide and cerebral vasospasm
- Principal Investigator
  
  SAITO Akira
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba
エンドセリンの薬理学的研究
- Principal Investigator
  
  真崎知生, MASAKI Tomoh (眞崎知生)
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Tsukuba
  Kyoto University
Analysis of effect of endothelin on blood pressure and its physiological meanings
- Principal Investigator
  
  MASAKI Tomoh
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  KYOTO UNIVERSITY
  University of Tsukuba
Pharmacological and biological studies of an endothelium-derived vasoconstrictive peptide, endothelium.
- Principal Investigator
  
  MASAKI Tomoh
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto University
  University of Tsukuba
The control by peripheral nerves of the function and drug senaitivity of the cadiac muscle and coronary blood vessel.Principal Investigator
- Principal Investigator
  
  GOTO Katsutoshi
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tsukuba

All 2006 2005 2004 2003 2002 2001 Other

All Journal Article

[Journal Article] Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner.2006
- Author(s)
  Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T
- Journal Title
  
  J Neurophysiol. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005
- Author(s)
  Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M
- Journal Title
  
  Neuron 46(2)
  
  Pages: 297-308
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Cholecystokinin Activates Orexin/Hypocretin Neurons through the Cholecystokinin A Receptor.2005
- Author(s)
  Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T
- Journal Title
  
  J Neurosci. 25(32)
  
  Pages: 7459-69
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005
- Author(s)
  Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M.
- Journal Title
  
  Neuron. 46(2)
  
  Pages: 297-308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005
- Author(s)
  Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M.
- Journal Title
  
  Neuron 46(2)
  
  Pages: 297-308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005
- Author(s)
  Sakurai T, Nagata R, Yamanaka A, Kawamura H.Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M
- Journal Title
  
  Neuron. 46(2)
  
  Pages: 297-308
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005
- Author(s)
  Sakurai T, Yamanaka A, Goto K, et al.
- Journal Title
  
  Neuron 46(2)
  
  Pages: 297-308
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Cholecystokinin Activates Orexin/Hypocretin Neurons through the Cholecystokinin A Receptor.2005
- Author(s)
  Tsujino N, Yamanaka A, Goto K, Sakurai T, et al.
- Journal Title
  
  J Neurosci. 25(32)
  
  Pages: 7459-7469
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Cholecystokinin Activates Orexin/Hypocretin Neurons through the Cholecystokinin A Receptor.2005
- Author(s)
  Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T.
- Journal Title
  
  J Neurosci. 25(32)
  
  Pages: 7459-7469
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Emergence of clinical applications of endothelin system inhibitors.2004
- Author(s)
  Goto K, Miyauchi T, et al.
- Journal Title
  
  Journal of Cardiovascular Pharmacololgy 44
  
  Pages: 13-14
- Data Source
  KAKENHI-PROJECT-15390077
[Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.2004
- Author(s)
  Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T
- Journal Title
  
  J Neurosci. 24(32)
  
  Pages: 7159-66
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.2004
- Author(s)
  Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T.
- Journal Title
  
  J Neurosci. 24(32)
  
  Pages: 7159-7166
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.2004
- Author(s)
  Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T.
- Journal Title
  
  J.Neurosci. 24(32)
  
  Pages: 7159-7166
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.2004
- Author(s)
  Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T.
- Journal Title
  
  J Neurosci. 24(32)
  
  Pages: 7159-7166
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Chronic administration of an endothelin-A receptor antagonist improves exercise capacity in rats with myocardial infarction-induced congestive heart failure2004
- Author(s)
  Miyauchi T, Fujimori A, Maeda S, Iemitsu M, Sakai S, Shikama H, Tanabe T, Matsuda M, Goto K, Yamaguchi I.
- Journal Title
  
  Journal of Cardiovascular Pharmacology 44
  
  Pages: 64-67
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390077
[Journal Article] Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisomeproliferator-activated receptor-α partly via blockade of c-Jun NH2-terminal kinase pathway2004
- Author(s)
  Irukayama-Tomobe Y, Miyauchi T, Sakai S, Kasuya Y, Ogata T, Takanashi M, Iemitsu M, Sudo T, Goto K, Yamaguchi I.
- Journal Title
  
  Circulation 109
  
  Pages: 904-910
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390077
[Journal Article] Establishment of hypoxia inducible factor-1α overexpressing cells that produce endothelin-12004
- Author(s)
  Takanashi M, Miyauchi T, Kakinuma Y, Goto K, Yamaguchi I.
- Journal Title
  
  Journal of Cardiovascular Pharmacology 44
  
  Pages: 168-273
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390077
[Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HTIA receptor.2004
- Author(s)
  Muraki Y, Yamanaka A, Goto K. et al.
- Journal Title
  
  J.Neurosci. 24(32)
  
  Pages: 7159-7166
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Hypothalamic orexin neurons regulate arousal according to energy balance in mice.2003
- Author(s)
  Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami K, Sugiyama F, Goto K, Yanagisawa M, Sakurai T
- Journal Title
  
  Neuron 38(5)
  
  Pages: 701-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Regulation of orexin neurons by the monoaminergic and cholinergic systems.2003
- Author(s)
  Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T.
- Journal Title
  
  Biochem Biophys Res Commun 303(1)
  
  Pages: 120-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Hypothalamic Orexin neurons regulate arousal according to energy balance in mice.2003
- Author(s)
  Yamanaka A., Beuckmann CT., Willie JT., Hara J., Tsujino N., Mieda M., Tominaga M., Yagami K., Sugiyama F., Goto K., Yanagisawa M., Sakurai T.
- Journal Title
  
  Neuron. 38
  
  Pages: 701-713
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Orexin receptor type-1 couples exclusively to pertussis toxin insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins2003
- Author(s)
  Zhu Y., Miwa Y., Yamanaka A., Yada T., Shibahara M., Abe Y., Sakurai T., Goto K.
- Journal Title
  
  J.Pharmacol.Sci. 92
  
  Pages: 259-266
- NAID
  10011209728
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Orexin receptor type-1 couples exclusively to pertussis toxin insensitive G-proteins, while orexin receptor type-2 couples t both pertussis toxin-sensitive and -insensitive G-proteins2003
- Author(s)
  Zhu Y., Miwa Y., Yamanaka A., Yada T., Shibahara M., Abe Y., Sakurai T., Goto K.
- Journal Title
  
  J.Pharmacol.Sci. 92
  
  Pages: 259-266
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Hypothalamic orexin neurons regulate arousal according to energy balance in mice.2003
- Author(s)
  Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami K, Sugiyama F, Goto K, Yanagisawa M, Sakurai T.
- Journal Title
  
  Neuron 38(5)
  
  Pages: 701-713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Regulation of orexin neurons by the monoaminergic and cholinergic systems.2003
- Author(s)
  Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T
- Journal Title
  
  Biochem Biophys Res Commun. 303(1)
  
  Pages: 120-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Regulation of orexin neurons by the monoaminergic and cholinergic systems.2003
- Author(s)
  Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 303(1)
  
  Pages: 120-129
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive nathwavs.2002
- Author(s)
  Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, Sakurai T.
- Journal Title
  
  Physiol Behav 77(2-3)
  
  Pages: 251-257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] The human prepro-orexin gene regulatory region that activates gene expression in the lateral region and represses it in the medial regions of the hypothalamus.2002
- Author(s)
  Moriguchi T, Sakurai T, Takahashi S, Goto K, Yamamoto M
- Journal Title
  
  J Biol Chem. 277(19)
  
  Pages: 16985-92
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Related Articles, The human prepro-orexin gene regulatory region that activates gene expression in the lateral region and represses it in the medial regions of the hypothalamus.2002
- Author(s)
  Moriguchi T, Sakurai T, Takahashi S, Goto K, Yamamoto M.
- Journal Title
  
  J Biol Chem. 277(19)
  
  Pages: 16985-16992
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Vascular endothelin-B receptor system in vivo plays a favorable inhibitory role in vascular remodeling after injury revealed by endothelin-B receptor-knockout mice.2002
- Author(s)
  Murakoshi N, Miyauchi T, Kakinuma Y, Ohuchi T, Goto K, Yanagisawa M, Yamaguchi I
- Journal Title
  
  Circulation 106(15)
  
  Pages: 1991-1998
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470147
[Journal Article] Orexins activate histaminergic neurons via the orexin 2 receptor.2002
- Author(s)
  Yamanaka A, Tsujino N, Funahashi H, Honda K, Guan JL, Wang QP, Tominaga M, Goto K, Shioda S, Sakurai T
- Journal Title
  
  Biochem Biophys Res Commun. 290(4)
  
  Pages: 1237-45
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Involvement of endogenous endothelin-1 in exercise-induced redistribution of tissue blood flow An endothelin receptor antagonist reduces the redistribution.2002
- Author(s)
  Maeda S, Miyauchi T, Iemitsu M, Tanabe T, Irukayama-Tomobe Y, Goto K, Yamaguchi I, Matsuda M
- Journal Title
  
  Circulation 106(17)
  
  Pages: 2188-2193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470147
[Journal Article] Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive pathways.2002
- Author(s)
  Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, Sakurai T.
- Journal Title
  
  Physiol.Behav. 77(2-3)
  
  Pages: 251-257
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370029
[Journal Article] Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive pathways.2002
- Author(s)
  Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, Sakurai T.
- Journal Title
  
  Physiol Behav. 77(2-3)
  
  Pages: 251-257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive pathways.2002
- Author(s)
  Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, Sakurai T
- Journal Title
  
  Physiol Behav. 77(2-3)
  
  Pages: 251-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Regulation of orexin neurons by the monoaminergic and cholinergic systems.2002
- Author(s)
  Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T.
- Journal Title
  
  Biochem Biophys Res Commun. 303(1)
  
  Pages: 120-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] A combination of oral endothelin-A receptor antagonist and oral prostacyclin analogue is superior to each drug alone in ameliorating pulmonary hypertension in rats2002
- Author(s)
  Ueno M, Miyauchi T, Sakai S, Yamauchi-Kohno R, Goto K, Yamaguchi I
- Journal Title
  
  Journal of the American College of Cardiology 40(1)
  
  Pages: 175-181
- NAID
  10010226459
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470147
[Journal Article] Orexins activate histaminergic neurons via the orexin 2 receptor.2002
- Author(s)
  Yamanaka A, Tsujino N, Funahashi H, Honda K, Guan JL, Wang QP, Tominaga M, Goto K, Shioda S, Sakurai T.
- Journal Title
  
  Biochem Biophys Res Commun. 290(4)
  
  Pages: 1237-1245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104009
[Journal Article] Novel molecular mechanism of increased myocardial endothelin-1 expression in the failing heart involving the transcriptional factor hypoxia-inducible factor-1α induced for impaired myocardial energy metabolism.2001
- Author(s)
  Kakinuma Y, Miyauchi T, Yuki K, Murakoshi N, Goto K, Yamguchi I
- Journal Title
  
  Circulation 103(19)
  
  Pages: 2387-2394
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12470147
[Journal Article] Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner.
- Author(s)
  Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T.
- Journal Title
  
  J Neurophysiol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14104009

1. SAKURAI Takeshi (60251055)

# of Collaborated Projects: 12 results

# of Collaborated Products: 31 results
2. KASUYA Yoshitoshi (70221877)

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3. MIYAUCHI Takashi (60222329)

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4. MASAKI Tomoh (60009991)

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5. SAITO Akira (40137708)

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7. YAMANAKA Akihiro (60323292)

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8. 井村裕夫 (10025570)

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9. YANAGISAWA Masashi (20202369)

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10. TAIRA Norio (60004553)

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13. ISHIKAWA Tomohisa (10201914)

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14. YAZAKI Yoshio (20101090)

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15. TODA Noboru (50025590)

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17. SHIGENO T (20170863)

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18. GOTO Katsutoshi (60072766)

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19. MUKAI Hidehito (20251027)

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38. NISHIKIBE Masaru

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58. 錦辺優

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GOTO Katsutoshi 後藤 勝年

和藤 勝年 ゴトウ カツトシ

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The analysis of the mechanisms of sleep/wakefulness and feeding behavior regulated by orexinPrincipal Investigator

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摂食行動に関与する新規神経ペプチド、オレキシンの生理作用に関する研究Principal Investigator

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Exploration of the novel therapeutic methods for the treatment of chronic circulatory diseasesPrincipal Investigator

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The role new pepdidergic neuron in autoregulation of regional blood flow.Principal Investigator

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GOTO Katsutoshi 後藤勝年

和藤勝年ゴトウカツトシ