TAKESHITA Akira 竹下彰

Researcher Number	30038814
External Links
Affiliation (based on the past Project Information) *help	2004: KYUSHU UNIVERSITY, Graduate School of Medical Sciences, Emeritus Professor, 大学院・医学研究院, 名誉教授 2003 – 2004: 九州大学, 名誉教授 2003: 九州大学, 医学研究院, 名誉教授 2000 – 2003: Kyushu Univ, Dept of Cardiovasc Med, Prof, 大学院・医学研究院, 教授 2000 – 2002: 九州大学, 医学研究院, 教授 … More 2000: Kyushu Univ, Dept of Cardiovasc Med, Prof, 医学研究院, 講師 1999: 九州大学, 大学院・医学系研究科, 教授 1990 – 1998: 九州大学, 医学部, 教授 1986 – 1989: 九州大学, 医学部, 助教授 1986: Kyushu University, Faculty of Medicine, associate professor, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / 応用薬理学・医療系薬学 / Physical pharmacy
Keywords	Principal Investigator 心不全 / Rho-kinase / 動脈硬化 / nitric oxide / 血管内皮 / 一酸化窒素 / アンジオテンシンII / 心筋細胞 / 冠動脈攣縮 / シグナル伝達 … More / 炎症 / 組織因子 / アンジオテンシン変換酵素 / EDHF / アンギオテンシン変換酵素 / セロトニン / 内皮細胞 / 狭心症 / sympathetic nerve activity / muscimol / GABA / 高血圧 / 転写因子 / トロンビン / 微小管 / 細胞骨格 / 不全心 / 心肥大 / 冠動脈 / forearm blood flow / aortic depressor nerve / baroreceptors / ANP / 側枢室内投与 / 大動脈径 / 動脈圧受容器 / 反射性交感神経活動調節 / 心房性ナトリウム利尿ペプチド(ANP) / 前腕血流量 / 大動脈減圧神経 / 腎交感神経 / 圧受容器反射 / 心房性Na利尿ペプチド / Atrial natriuretic peptide / Spontaneously hypertensive rat / High salt intake / Cardiopulmonary baroreflex / 心房筋伸展 / 心房性ナトリウム利尿ペブチド / 高血圧自然発生ラット / 高食塩食摂取 / 心肺圧受容体 / Pulmonary hypertension / Heart failure / Myocardial infarction / Restenosis / Cardiac hypertrophy / Atherosclerosis / Vasospastic angina / Rho / 肺高血圧症 / 心筋梗塞 / 再狭窄 / 冠攣縮性狭心症 / Rho-Kinase / regression / coronary vasospasm / signal transduction / ischemic heart disease / coronary artery / arteriosclerossis / 動脈硬化の退縮 / Rhoーkinase / 冠攣縮 / サイトカイン / 退縮 / 虚血性心疾患 / fibrosis / inflammation / arteriosclerosis / MCP-1 / NF-κB / gene transfer / ケモカイン / monocyte chemoattractant protein-1 / atherosclerosis / thrombosis / angiotensin II / angiotensin-converting enzyme / プラスミノーゲンアクチヴェーター阻害剤 / プラスミノーゲンアクチヴェーター / 一酸化窒素、 / 急性心筋梗塞症 / 冠動脈血栓症 / 血栓 / Microvessels / Nitric oxide / K channels / 血管平滑筋 / 内皮由来過分極因子 / 内皮依存性弛緩反応 / 一酸化窒素(NO) / 内皮由来過分極因子(EDHF) / 微小血管 / NO / Kチャネル / angiotensin-converting enzyme inhibitor / papaverine / serotonin / coronary circulation / endothelial cell / angina pectoris / 心筋虚血 / 内皮細胞由来一酸化窒素 / 血管内皮細胞 / アンギオテンシン変換酵素阻害薬 / パパベリン / 冠循環 / shaker stress / NaCl / borderline hypertensive rat / 脳室内投与 / ビククリン / ムシモ-ル / ストレス / 境界型高血圧 / 食塩 / 交感神経活動 / 振盪ストレス刺激 / 食塩負荷 / 境界型高血圧ラット / カプトリル / handgrip運動 / 骨格筋栄養血流量 / AP-1 / オリゴペプチド / アルギニンポリマー / dominant negative / アポトーシス / cAMP response element binding protein / 腫瘍壊死因子 / 組織特異的発現 / サブトラクションクローニング / 心筋肥大 / ノーザンブロット / カルセクエストリン / Ca^<2+> / 筋小胞体 / サルコメア / 収縮能 / 肥大心 / L-NMMA / L-NAME / ブタ / 内皮由来血管弛緩物質 / メチレンブルー / ヘモグロビン / NMMA / スライス標本 / L-arginine / nitnic oxide / サブスタンス-P / L-アルジニン / No / Lーarginine / アセチルコリン / 前椀血流量 / 内非依存性血管拡張 … More Except Principal Investigator 動脈硬化 / 冠動脈攣縮 / セロトニン / 遺伝子治療 / 再狭窄 / ARTERIOSCLEROSIS / INTRAMURAL HEMORRHAGE / MYOCARDIAL INFARCTION / 血管壁内出血 / 急性心筋梗塞 / WHHL / 突然死 / 血管内皮細胞 / 内皮細胞 / atherosclerosis / reactive oxygen species / free radical / 心不全 / 糖尿病 / 生体計測ESR / スピンプローブ / MRI / 活性酸素 / フリーラジカル / endothelium / serotonin / substance P / EDRF / デリバリーシステム / 留置型ステント / 組換えアデノウイルス / 心筋梗塞 / 心筋虚血 / WHHL RABBIT / STUNNED MYOCARDIUM / ANIMAL MODEL / rt-PA / THROMBOLYSIS / 冠動脈硬化 / 血栓性閉塞 / 組織プラスミノーゲンアクチベータ / 遺伝性高脂血症家兎 / 血栓溶解療法 / stunned myocardium / 再潅流障害 / 急性心筋梗塞発症 / 血栓溶解剤 / 心筋梗塞サイズ / 再灌流 / 組織プラスミノ-ゲンアクチベ-タ- / Doppler-flow velocity / coronary reserve / coronary blood flow / 経皮的冠動脈形成術 / 肥大心 / ドプラー血流計 / ドップラ-血流計 / 冠予備能 / 冠血流量 / ENDOTHELIAL CELL / PTCA / SEROTONIN / CORONARY ARTERY SPASM / 中膜平滑筋 / X線照射 / 粥種内出血 / 冠動脈硬化とその進展 / 内皮細胞依存性血管弛緩 / 経皮経管形成術 / 流動脈攣縮 / rabbits / vagus / aortic baroreceptors / aortic diameter / aortic depressor nerve / renal sympathetic nerve / atrial natriuretic peptide / 腎機能 / 迷走神経 / 大動脈径 / 動脈圧受容体 / 大動脈減圧神経 / 家兎 / ラット / 腎交感神経 / 心房性利尿ホルモン / Hyperlipifemia / WHHL rabbvit / Miniature Pig / Serotonin / Intramural hemorrhage / Myocardial infarction / Coronary artery spasm / 動物モデル / 狭心症 / 冠動脈〓縮 / 高脂血症 / ミニ豚 / 高コレステロール血症 / 急性心筋梗塞症 / vascular smooth muscle / caffeine / histamine / coronaryarteryspasm / カフェイン / 細胞内Ca^<++> / quin-2 / 内皮細胞依存性弛緩 / ヒスタミン / nitroxyl radical / obese / diabetes / electron spin resonance / トランスジェニックマウス / 無侵襲解析 / 循環器疾患 / ニトロキシルラジカル / 肥満 / 電子スピン共鳴 / monocytes / gene therapy / inflammation / restenosis / 単球 / 炎症 / ischemic-reperfusion injury / gastrointestinal injury / disease analysis / oxidative stress / ESR / 活性窒素 / スピントラップ / 胃潰瘍 / ESRI・MRI / 虚血再灌流障害 / 消化管障害 / 病態解析 / 酸化ストレス / ESRI / dysfunction / endothelium-derived relaxing factor / coronary artery spasm / 血管内皮細胞依存性弛緩 / Ca^<2+>チャネル / Ca^<2+>ーカイネティックス / サブスタンスP / 内皮細胞依存性血管弛緩因子 / 冠攣縮 / substaucep / coronary spasm / endo the lium / couonay spasm / 内皮由来弛緩物質 / 血管内皮 / 一酸化窒素(NO) / 内皮由来過分極因子(EDHF) / C型Na利尿ペプチド / 血管外膜 / 血管リモデリング / 循環調節 / 周波数解析 / フ-リエ変換 / ホワイトノイズ法 / 心レセプタ- / 神経反射 Less

アルギニンポリマーを用いたオリゴペプチドの細胞核内導入による血管病変の蛋白治療Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Anti-inflammation therapy targeting monocyte chemoattractant protein-1 as novel strategy to treat cardiovascular disease
- Principal Investigator
  
  EGASHIRA Kensuke
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Non-invasive analysis of dynamic state of reactive oxygen species in tissue and blood vessel of circulatory diseases
- Principal Investigator
  
  UTSUMI Hideo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyushu University
Role of Rho/Rho-kinase-mediated pathway in the pathogenesls of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  SHIMOKAWA Hiroaki, 竹下彰
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Development of ESRI・MRI fused imaging device for oxidative stress-related diseases
- Principal Investigator
  
  UTSUMI Hideo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyushu University
平滑筋細胞の分化増殖および血管病変形成におけるCREBの果たす役割に関する研究Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
血管リモデリングの成因における外膜の炎症性・増殖性機序の役割遺伝子導入法を用いた検討
- Principal Investigator
  
  下川宏明
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
内皮由来過分極因子(EDHF)は内皮型一酸化窒素合成酵素由来である可能性-ノックアウトマウスを用いた検討-
- Principal Investigator
  
  下川宏明
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
MOLECULAR MECHANISMS OF CARDIOVASCULAR REMODELING INDUCED BY CHRONIC INHIBITION OF NITRIC OXIDE SYNTHESIS : ROLE OF NF-κB AND MCP-1Principal Investigator
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Development of intracellular therapy to induce a regression of coronary arteriosclerotic lesionsPrincipal Investigator
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
肥大心に特異的に発現する遺伝子のSubtraction法による単離とその機能解析Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
指向性蛋白含有リポゾームとの結合によるアデノウィルスの細胞選択的導入法の開発-血小板膜糖蛋白GPIbを利用した傷害血管選択的遺伝子導入法の開発-
- Principal Investigator
  
  上野光
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
不全心における細胞骨格-細胞外マトリックスと細胞接着分子の役割に関する研究Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
組換えアデノウイルスを吸着・放出できる冠動脈留置ステントの開発とその応用
- Principal Investigator
  
  上野光
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
機械的ストレスによる心肥大形成の細胞・分子機構における細胞骨格の役割に関する研究Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Physiological and pathophysiological roles of endothelium-derived hyperpotarizing factor in the control of organ perfusion.Principal Investigator
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY FACULTY OF MEDICINE
molecular mechanisms of vascular thrombosisPrincipal Investigator
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
心肥大形成における細胞骨格の役割についての細胞・分子生物学的研究Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
ROLE OF MICROVASCULAR DISORDERS IN THE PATHOGENESIS OF MYOCARDIAL ISCHEMIAPrincipal Investigator
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY FACULTY OF MEDICINE
心不全における内皮依存性血管拡張能異常に関する研究Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
心不全における内皮依存性血勘拡張能異常に関する研究Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
孤束核ニューロンのシナプス伝達における酸化窒素の役割に関する研究:特に逆行性精報伝達物質としての可能性についてPrincipal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
心不全における内皮依存性血管拡張能異常に関する研究Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Role of central GABA system in hypertension induced by high salt and stress.Principal Investigator
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Cellular and Molecular Mechanism Coronary Spasm
- Principal Investigator
  
  KOYANAGI Samon, 丸岡雄二
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
心筋虚血時の反射性循環調節異常に関する検討
- Principal Investigator
  
  IMAIZUMI Tsutomu
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Pathophysiological Events Related to Coronary Spasm and Provocation of Intramural Hemorrhage at the Spastic Site.
- Principal Investigator
  
  NAKAMURA Motoomi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Pathophysiological studies of regulation and reserve of coronary circulation
- Principal Investigator
  
  KOYANAGI Samon
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Development and assessment of animal models appropriate for evaluating thrombolytic agents for an early treatment of acute myocardial infarction
- Principal Investigator
  
  NAKAMURA Motoomi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Research Institute of Angiocardiology and Cardiovascular Clinic Faculty of Medicine, Kyushu University
心不全における運動時の骨格筋栄養血流量調節に関する研究Principal Investigator
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University
The role of atrial natriuretic peptide in control of circulation and body fluid in heart failurePrincipal Investigator
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Effects of atrial natriuretic peptide on renal nerve activity
- Principal Investigator
  
  TSUTOMU IMAIZUMI
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Relationship between the evolution of coronary artery spasm and atherosclerosis and related basic studies on the mechanisms of coronary spasm
- Principal Investigator
  
  NAKAMURA Motoomi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Establishment of animal models with acuto myocardial infaroction and/or suuden death
- Principal Investigator
  
  NAKAMURA Motoomi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Factors contributing to increases in circulating hypertensive peptides in genetic hypertensionPrincipal Investigator
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University

All 2004 2003 2002

All Journal Article

[Journal Article] Essential Role of Vascular Endothelial Growth Factor and Flt-1 Signals in Neointimal Formation After Periadventitial Injury.2004
- Author(s)
  Zhao Q, Egashira K, Hiasa K, Ishibashi M, Inoue S, Ohtani K, Tan C, Shibuya M, Takeshita A
- Journal Title
  
  Arterioscler Thromb Vase Biol. 24
  
  Pages: 2284-2289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Essential Role of Vascular Endothelial Growth Factor in Angiotensin II-Induced Vascular Inflammation and Remodeling.2004
- Author(s)
  Zhao Q, Ishibashi M, Hiasa K, Tan C, Takeshita A, Egashira K
- Journal Title
  
  Hypertension 44
  
  Pages: 264-270
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Monocyte Chemoattractant Protein-1 is an essential inflammatory mediator in angiotensin II-induced progression of established atherosclerosis in hypercholesterolemic mice.2004
- Author(s)
  Ni W, Kitamoto S, Ishibashi M, Usui M, Inoue S, Hiasa K, Zhao Q, Nishida K, Takeshita A Egashira K
- Journal Title
  
  Arterioscl Throm Vas Biol 24
  
  Pages: 534-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Gene Transfer of Stromal Cell-Derived Factor-1 α Enhances Ischemic Vasculogenesis and Angiogenesis via Vascular Endothelial Growth Factor / Endothelial Nitric Oxide Synthase-Related Pathway : Next-Generation Chemokine Therapy for Therapeutic Neovascularizaiton2004
- Author(s)
  Hiasa K, Ishibashi M, Otani K, Inoue S, Zhao Q, Kitamoto S, Sata M, Ichiki T, Takeshita A, Egashira K
- Journal Title
  
  Circulation 109(20)
  
  Pages: 2454-2461
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Inhibition of neointimal hyperplasia after balloon injury by cis-element decoy' of early growth response gene-1 in hypercholesterolemic rabbits.2004
- Author(s)
  Ohtani K, Egashira K, Usui M, Ishibashi M, Hiasa K-I, Zhao Q, Aoki M, Kaneda Y, Morishita R, Takeshita A
- Journal Title
  
  Gene Ther. 11
  
  Pages: 126-132
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Bone Marrow-Derived Monocyte Chemoattractant Protein-1 Receptor CCR2 Is Critical in Angiotensin II-Induced Acceleration of Atherosclerosis and Aneurysm Formation in Hypercholesterolemic Mice.2004
- Author(s)
  Ishibashi M, Egashira K, Zhao Q, Hiasa K, Ohtani K, Ihara Y, Charo IF, Kura S, Tsuzuki T, Takeshita A, Sunagawa K
- Journal Title
  
  Arterioscler Thromb Vase Biol. 24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Bone marrow mononuclear cell therapy limits myocardial infarct size through vascular endothelial growth factor.2004
- Author(s)
  Hiasa K, Egashira K, Kitamoto S, Ishibashi M, Inoue S, Ni w, Zhao W, Nagata S, Katoh M, Sata M, Takeshita A
- Journal Title
  
  Basic Research in Cardiology 99
  
  Pages: 162-172
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Gene Transfer of Stromal Cell-Derived Factor-1α Enhances Ischemic Vasculogenesis and Angiogenesis via Vascular Endothelial Growth Factor / Endothelial Nitric Oxide Synthase-Related Pathway : Next-Generation Chemokine Therapy for Therapeutic Neovascularizaiton2004
- Author(s)
  Hiasa K, Ishibashi M, Otani K, Inoue S, Zhao Q, Kitamoto S, Sata M, Ichiki T, Takeshita A, Egashira K
- Journal Title
  
  Circulation 109
  
  Pages: 2454-2461
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Critical Role of Monocyte Chemoattractant Protein-1 Receptor CCR2 on Monocytes in Hypertension-Induced Vascular Inflammation and Remodeling.2004
- Author(s)
  Ishibashi M, Hiasa K, Zhao Q, Inoue S, Ohtani K, Kitamoto S, Tsuchihashi M, Sugaya T, Israel F, Charo, MD, Kura S, Tsuzuki T, Ishibashi T, Takeshita A, Egashira K
- Journal Title
  
  Circulation Research 94
  
  Pages: 1203-1210
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] cAMP -Response Element-Binding Protein Mediates Tumor Necrosis Factor-α-induced Vascular Smooth Muscle Cell Migration.2004
- Author(s)
  Ono H, Ichiki T, Fukuyama K, Iino N, Masuda S, Egashira K, Takeshita A
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 24
  
  Pages: 1634-1639
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Inhibition of neointimal hyperplasia after balloon injury by cis-element decoy' of early growth response gene-1 in hypercholesterolemic rabbits.2004
- Author(s)
  Ohtani K, Egashira K, Usui M, Ishibashi M, Hiasa K-I, Zhao Q, Aoki M, Kaneda Y, Morishita R, Takeshita A
- Journal Title
  
  Gene Ther. 11(2)
  
  Pages: 126-132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary fibrosis in mice.2004
- Author(s)
  Inoshima I, Kuwano K, Hamada N, Hagimoto N, Yoshimi M, Maeyama T, Takeshita A, Kitamoto S, Egashira K, Hara N
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol 286(5)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Bone Marrow-Derived Monocyte Chemoattractant Protein-1 Receptor CCR2 Is Critical in Angiotensin II- Induced Acceleration of Atherosclerosis and Aneurysm Formation in Hypercholesterolemic Mice.2004
- Author(s)
  Ishibashi M, Egashira K, Zhao Q, Hiasa K, Ohtani K, Ihara Y, Charo IF, Kura S, Tsuzuki T, Takeshita A, Sunagawa K
- Journal Title
  
  Arterioscler Thromb Vasc Biol 24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Reduces Experimental Ln-Stent Restenosis in Hypercholesterolemic Rabbits and Monkeys.2004
- Author(s)
  Ohtani K, Usui M, Nakano K, Kohjimoto Y, Kitajima S, Hirouchi Y, Li X, Kitamoto S, Takeshita A, Egashira K
- Journal Title
  
  Gene Therapy 11
  
  Pages: 1273-1282
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Monocyte Chemoattractant Protein-1 is an essential inflammatory mediator in angiotensin II-induced progression of established atherosclerosis in hypercholesterolemic mice.2004
- Author(s)
  Ni W, Kitamoto S, Ishibashi M, Usui M, Inoue S, Hiasa K, Zhao Q, Nishida K, Takeshita A, Egashira K
- Journal Title
  
  Arterioscl Throm Vas Biol 24
  
  Pages: 534-539
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Essential Role of Vascular Endothelial Growth Factor in Angiotensin II-Induced Vascular Inflammation and Remodeling.2004
- Author(s)
  Zhao Q, Ishibashi M, Hiasa K, Tan C, Takeshita A, Egashira K
- Journal Title
  
  Hypertension 44(3)
  
  Pages: 264-270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Bone marrow mononuclear cell therapy limits myocardial infarct size through vascular endothelial growth factor.2004
- Author(s)
  Hiasa K, Egashira K, Kitamoto S, Ishibashi M, Inoue S, Ni w, Zhao W, Nagata S, Katoh M, Sata M, Takeshita A
- Journal Title
  
  Basic Research in Cardiology 99(3)
  
  Pages: 165-172
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Hypertensive myocardial fibrosis and diastolic dysfunction Another model of inflammation-.2004
- Author(s)
  Kuwahara F, Kai H, Tokuda K, Takeya M, Takeshita A, Egashira K, Imaizumi T
- Journal Title
  
  Hypertension 43
  
  Pages: 739-745
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Novel anti-inflammatory actions of amlodipine in a rat model of arteriosclerosis induced by long-term inhibition of nitric oxide synthesis.2004
- Author(s)
  Kataoka C, Egashira K, Ishibashi M, Inoue S, Ni W, Hiasa K, Kitamoto S, Usui M, Takeshita A
- Journal Title
  
  Am J Physiol Heart-C (Epub 2003 Oct 30) 286(2)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] cAMP-Response Element-Binding Protein Mediates Tumor Necrosis Factor-α-induced Vascular Smooth Muscle Cell Migration.2004
- Author(s)
  Ono H, Ichiki T, Fukuyama K, Iino N, Masuda S, Egashira K, Takeshita A
- Journal Title
  
  Arterioscler Thromb Vase Biol. 24(9)
  
  Pages: 1634-1639
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Essential Role of Vascular Endothelial Growth Factor and Flt-1 Signals in Neointimal Formation After Periadventitial Injury.2004
- Author(s)
  Zhao Q, Egashira K, Hiasa K, Ishibashi M, Inoue S, Ohtani K, Tan C, Shibuya M, Takeshita A
- Journal Title
  
  Arterioscler Thromb Vasc Biol 24
  
  Pages: 2284-2289
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Novel anti-inflammatory actions of amlodipine in a rat model of arteriosclerosis induced by long-term inhibition of nitric oxide synthesis.2004
- Author(s)
  Kataoka C, Egashira K.Ishibashi M, Inoue S, Ni W, Hiasa K, Kitamoto S, Usui M, Takeshita A
- Journal Title
  
  Am J Physiol Heart- C 286
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Bone Marrow-Derived Monocyte Chemoattractant Protein-1 Receptor CCR2 Is Critical in Angiotensin II-Induced Acceleration of Atherosclerosis and Aneurysm Formation in Hypercholesterolemic Mice.2004
- Author(s)
  Ishibashi M, Egashira K, Zhao Q, Hiasa K, Ohtani K, Ihara Y, Charo IF, Kura S, Tsuzuki T, Takeshita A, Sunagawa K
- Journal Title
  
  Arterioscler Thromb Vasc Biol 24
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Critical Role of Monocyte Chemoattractant Protein-1 Receptor CCR2 on Monocytes in Hypertension-Induced Vascular Inflammation and Remodeling.2004
- Author(s)
  Ishibashi M, Hiasa K, Zhao Q, Inoue S, Ohtani K, Kitamoto S, Tsuchihashi M, Sugaya T, Israel F. Charo, MD ; Kura S, Tsuzuki T, Ishibashi T, Takeshita A, Egashira K
- Journal Title
  
  Circulation Research 94
  
  Pages: 1203-1210
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] In vivo oxygen radical generation in the skin of the protoporphyria model mouse with visible light exposure : An L-band ESR study2004
- Author(s)
  Takeshita, K, Takajo, T, Hirata, H, Ono, M, Utsumi, H.
- Journal Title
  
  JOURNAL OF INVESTIGATIVE DERMATOLOGY 122(6)
  
  Pages: 1463-1470
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207105
[Journal Article] Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary fibrosis in mice.2004
- Author(s)
  Inoshima I, Kuwano K, Hamada N, Hagimoto N, Yoshimi M, Maeyama T, Takeshita A, Kitamoto S, Egashira K, Hara N
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol 286
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice.2004
- Author(s)
  Shiomi, T., Tsutsui, H., Matsusaka, H., Murakami, K., Hayashidani, S., Ikeuchi, M., Wen, J., Kubota, T., Utsumi, H., Takeshita, A.
- Journal Title
  
  Circulation 109
  
  Pages: 544-549
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207105
[Journal Article] Critical Role of Monocyte Chemoattractant Protein-1 Receptor CCR2 on Monocytes in Hypertension-Induced Vascular Inflammation and Remodeling.2004
- Author(s)
  Ishibashi M, Hiasa K, Zhao Q, Inoue S, Ohtani K, Kitamoto S, Tsuchihashi M, Sugaya T, Israel F.Charo, MD, Kura S, Tsuzuki T, Ishibashi T, Takeshita A, Egashira K
- Journal Title
  
  Circulation Research 94
  
  Pages: 1203-1210
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] In vivo oxygen radical generation in the skin of the protoporphyria model mouse with visible light exposure : An L-band ESR study2004
- Author(s)
  Takeshita, K. et al.
- Journal Title
  
  JOURNAL OF INVESTIGATIVE DERMATOLOGY 122(6)
  
  Pages: 1463-1470
- Data Source
  KAKENHI-PROJECT-14207105
[Journal Article] In vivo oxygen radical generation in the skin of the protoporphyria model mouse with visible light exposure: An L-band ESR study2004
- Author(s)
  Takeshita, K, Takajo, T, Hirata, H, Ono, M, Utsumi, H
- Journal Title
  
  Journal of Investigative Dermatology 17
  
  Pages: 295-302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207105
[Journal Article] Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Reduces Experimental In-Stent Restenosis in Hypercholesterolemic Rabbits and Monkeys.2004
- Author(s)
  Ohtani K, Usui M, Nakano K, Kohjimoto Y, Kitajima S, Hirouchi Y, Li X, Kitamoto S, Takeshita A, Egashira K
- Journal Title
  
  Gene Therapy 11
  
  Pages: 1273-1282
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti-monocyte chemoattractant protein-1 gene therapy attenuates left ventricular remodeling and failure after experimental myocardial infarction.2003
- Author(s)
  Hayashidani S, Tsutsui H, Shiomi T, Ikeuchi M, Matsusaka H, Suematsu N, Wen J, Egashira K, Takeshita A
- Journal Title
  
  Circulation 108
  
  Pages: 2134-2140
- NAID
  110002637242
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Disparity of MCP-1 mRNA and Protein Expressions Between the Carotid Artery and the Aorta in WHHL Rabbits -One Aspect Involved in the Regional Difference in Atherosclerosis-2003
- Author(s)
  Tanaka E, Shimokawa H, Kamiuneten H, Eto Y, Matsumoto Y, Morishige K, Koike G Yoshinaga M, Egashira K, Tokunaga O, Shiomi M, Takeshita A
- Journal Title
  
  Arterioscl Throm Vas Biol 23
  
  Pages: 244-250
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Overexpression of tumor necrosis factor-alpha increases production of hydroxyl radical in murine myocardium.2003
- Author(s)
  Machida, Y., Kubota, T., Kawamura, N., Funakoshi, H., Ide, T., Utsumi, H., Li, Y.Y., Feldman, A.M., Tsutsui, H., Shimokawa, H., Takeshita, A
- Journal Title
  
  Am J Physiol Heart Circ Physiol 284
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207105
[Journal Article] Stress and Vascular Responses : Anti-inflammatory Therapeutic Strategy against Atherosclerosis and Restenosis after Coronary Intervention.2003
- Author(s)
  Kitamoto S, Egashira K, A Takeshita
- Journal Title
  
  J Pharm Sci 91
  
  Pages: 192-196
- NAID
  130000073699
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Downregulation of vascular angiotensin II type 1 receptor by thyroid hormone.2003
- Author(s)
  Fukuyama K, Ichiki T, Takeda K, Tokunou T, Iino N, Masuda S, Ishibashi M, Egashira K, Shimokawa H, Hirano K, Kanaide H, Takeshita A
- Journal Title
  
  Hypertension 41(3)
  
  Pages: 598-603
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Apoptosis induced by inhibition of cyclic AMP response element-binding protein in vascular smooth muscle cells.2003
- Author(s)
  Tokunou T, Shibata R, Kai H, Ichiki T, Morisaki T, Fukuyama K, Ono H, Iino N, Masuda S, Shimokawa H, Egashira K, Imaizumi T, Takeshita A
- Journal Title
  
  Circulation 108
  
  Pages: 1246-1252
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Stress and Vascular Responses : Anti-inflammatory Therapeutic Strategy against Atherosclerosis and Restenosis after Coronary Intervention.2003
- Author(s)
  Kitamoto S, Egashira K, Takeshita A
- Journal Title
  
  J Pharm Sci 91
  
  Pages: 192-196
- NAID
  130000073699
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Downregulation of vascular angiotensin II type 1 receptor by thyroid hormone.2003
- Author(s)
  Fukuyama K, Ichiki T, Takeda K, Tokunou T, Iino N, Masuda S, Ishibashi M, Egashira K, Shimokawa H, Hirano K, Kanaide H, Takeshita A
- Journal Title
  
  Hypertension 41
  
  Pages: 598-603
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Vitamin C Improves attenuated angiotensin II-Induced endothelium-dependent vasodilation in human forearm vessels.2003
- Author(s)
  Hirooka Y, Setoguchi S, Kishi, T, Egashira K, Takeshita A
- Journal Title
  
  Hypertens Res 26
  
  Pages: 953-959
- NAID
  50000378354
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Disparity of MCP-1 mRNA and Protein Expressions Between the Carotid Artery and the Aorta in WHHL Rabbits -One Aspect Involved in the Regional Difference in Atherosclerosis-2003
- Author(s)
  Tanaka E, Shimokawa H, Kamiuneten H, Eto Y, Matsumoto Y, Morishige K, Koike G, Yoshinaga M, Egashira K, Tokunaga O, Shiomi M, Takeshita A
- Journal Title
  
  Arterioscl Throm Vas Biol 23
  
  Pages: 244-250
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Vitamin C Improves attenuated angiotensin II-Induced endothelium-dependent vasodilation in human forearm vessels.2003
- Author(s)
  Hirooka Y, Setoguchi S, Kishi T, Egashira K, Takeshita A
- Journal Title
  
  Hypertens Res 26
  
  Pages: 953-959
- NAID
  50000378354
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti inflammatory and Antiarteriosclerotic Effects of Pioglitazone.2002
- Author(s)
  Ishibashi M, Egahira K, Hiasa K, Inoue S, Ni W, Zhao Q, Usui M, Kitamoto S, Takeshita A
- Journal Title
  
  Hypertension 40(5)
  
  Pages: 687-693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Inhibits Restenotic Changes (Neointimal Hyperplasia) After Balloon Injury in Rats and Monkeys.2002
- Author(s)
  Usui M, Egashira K, Ohtani K, Kataoka C, Ishibashi M, Hiasa K, Katoh M, Zhao QW, Kitamoto S, Takeshita A
- Journal Title
  
  FASEB J 16(5)
  
  Pages: 1838-1840
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Vascular Endothelial Growth Factor is Necessary in the Development of Arteriosclerosis by Recruiting/Activating Monocytes in a Rat Model of Long-Term Inhibition of Nitric Oxide Synthesis.2002
- Author(s)
  Zhao QW, Egashira K, Inoue S, Usui M, Kitamoto K, Ni WH, Ishibashi M, Hiasa K, Ichiki I, Shibuya M, Takeshita A
- Journal Title
  
  Circulation 105
  
  Pages: 1110-1115
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Probucol Attenuates Left Ventricular Dysfunction and Remodeling in Tachycardia-Induced Heart Failure -Roles of Oxidative Stress and Inflammation2002
- Author(s)
  Nakamura R, Egashira K, Machida Y, Hayashidani S, Takeya M, Utsumi H, Tsutsui H, Takeshita A
- Journal Title
  
  Circulation 106(3)
  
  Pages: 362-367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Vascular Endothelial Growth Factor is Necessary in the Development of Arteriosclerosis by Recruiting/Activating Monocytes in a Rat Model of Long-Term Inhibition of Nitric Oxide Synthesis.2002
- Author(s)
  Zhao QW, Egashira K, Inoue S, Usui M, Kitamoto K, Ni WH, Ishibashi M, Hiasa K, Ichiki I, Shibuya M, Takeshita A
- Journal Title
  
  Circulation 105(9)
  
  Pages: 1110-1115
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti-monocyte Chemoattractant Protein-1 Gene Therapy Attenuates pulmonary Attenuates Pulmonary Hypertension in Rats.2002
- Author(s)
  Ikeda Y, Yonemitsu Y, Kataoka C, Kitamoto S, Yamaoka Y, Kitamoto S, Yamaok T, Nishida K, Takeshita A, Egashira K, Sueishi K
- Journal Title
  
  Am J Physiol- Heart C 283
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure : roles of oxidative stress and inflammation.2002
- Author(s)
  Nakamura, R., Egashira, K., Machida, Y., Hayashidani, S., Takeya, M., Utsumi, H., Tsutsui, H., Takeshita, A.
- Journal Title
  
  Circulation 106
  
  Pages: 362-367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207105
[Journal Article] Post-b-receptor impairment in the regulation of myofibrillar Ca2+sensitivity in tachypacing-induced canine failing heart.2002
- Author(s)
  Satoh S, Suematsu N, Ueda Y, Tsutsui H, Egashira K, Takeshita A, Makino N
- Journal Title
  
  J Cardiovasc Pharm 39
  
  Pages: 88-97
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Long-term Inhibition of Nitric Oxide Synthesis Increases Arterial Thrombogenecity Through Angiotensin II-induced Expression of Tissue Factor and Resultant Production of Thrombin in Rats.2002
- Author(s)
  Kubo-Inoue M, Egashira K, Usui M, Takemoto M, Ohtani K, Katoh M, Shimokawa H, Takeshita A
- Journal Title
  
  Am J Physiol- Heart C 282
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Limits Progression and Destabilization of Established Atherosclerosis in Apolipoprotein E-Knockout Mice.2002
- Author(s)
  Inoue S, Egashira K, Ni WH, Kitamoto S, Usui M, Otani K, Ishibashi M, Hiasa K, Nishida K, Takeshita A
- Journal Title
  
  Circulation 106
  
  Pages: 2700-2706
- NAID
  110002637354
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure : roles of oxidative stress and inflammation.2002
- Author(s)
  Nakamura, R., Egasira, K., Machida, Y., Hayashidani, S., Takeya, M., Utsumi, H., Tsutsui, H., Takeshita, A.
- Journal Title
  
  Circulation 106
  
  Pages: 362-367
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207105
[Journal Article] Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Limits Progression and Destabilization of Established Atherosclerosis in Apolipoprotein E-Knockout Mice.2002
- Author(s)
  Inoue S, Egashira K, Ni WH, Kitamoto S, Usui M, Otani K, Ishibashi M, Hiasa K, Nishida K Takeshita A
- Journal Title
  
  Circulation 106
  
  Pages: 2700-2706
- NAID
  110002637354
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Importance of Monocyte Chemoattractant Protein-1 Pathway in Neointimal Hyperplasia After Peri-arterial Injury in Mice and Monkeys.2002
- Author(s)
  Egashira K, Zhao QW, Kataoka C, Ohtani K, Usui M, Charo IF, Nishida K, Inoue S, Katoh M, Ichiki T, Takeshita A
- Journal Title
  
  Circulation Research 90
  
  Pages: 1167-1172
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Pioglitazone, a Peroxisome Proliferator-Activated Receptor-γ Agonist, Attenuates Left Ventricular Remodeling and Failure After Experimental Myocardial Infarction.2002
- Author(s)
  Shiomi T, Tsutsui H, Hayashidani S, Suematsu N, Ikeuchi M, Wen J, Ishibashi M, Kubota T, Egashira K, Takeshita A
- Journal Title
  
  Circulation 106
  
  Pages: 3126-3132
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Transforming Growth Factor- β Function Blocking Prevents Myocardial Fibrosis and Diastolic Dysfunction in Pressure- Overloaded Rats.2002
- Author(s)
  Kuwahara F, Kai H, Tokuda K, Kai M, Takeshita A, Egashira K, Imaizumi T
- Journal Title
  
  Circulation 106
  
  Pages: 130-135
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti-monocyte Chemoattractant Protein-1 Gene Therapy Attenuates pulmonary Attenuates Pulmonary Hypertension in Rats.2002
- Author(s)
  Ikeda Y, Yonemitsu Y, Kataoka C, Kitamoto S, Yamaoka Y, Kitamoto S, Yamaok T, Nishida k, Takeshita A, Egashira K, Sueishi K
- Journal Title
  
  Am J Physiol-Heart C 283(5)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Probucol Attenuates Left Ventricular Dysfunction and Remodeling in Tachycardia-Induced Heart Failure -Roles of Oxidative Stress and Inflammation-2002
- Author(s)
  Nakamura R, Egashira K, Machida Y, Hayashidani S, Takeya M, Utsumi H, Tsutsui H, Takeshita A
- Journal Title
  
  Circulation 106
  
  Pages: 362-367
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Angiotensin-Converting Enzyme Activity is Involved in the Mechanism of Increased Endogenous Nitric Oxide Synthase Inhibitor in Patients With Typa 2 Diabetes Mellitus.2002
- Author(s)
  Ito A, Egashira K, Narishige T, Muramatsu K, Takeshita A
- Journal Title
  
  Circ J 66
  
  Pages: 811-815
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Angiotensin-Converting Enzyme Activity is Involved in the Mechanism of Increased Endogenous Nitric Oxide Synthase Inhibitor in Patients With Type 2 Diabetes Mellitus.2002
- Author(s)
  Ito A, Egashira K, Narishige T, Muramatsu K, Takeshita A
- Journal Title
  
  Circ J 66(9)
  
  Pages: 811-815
- NAID
  110002691001
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti inflammatory and Antiarteriosclerotic Effects of Pioglitazone.2002
- Author(s)
  Ishibashi M, Egashira K, Hiasa K, Inoue S, Ni W, Zhao Q, Usui M, Kitamoto S, Takeshita A
- Journal Title
  
  Hypertension 40
  
  Pages: 687-693
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Post-b-receptor impairment in the regulation of myofibrillar Ca2+sensitivity in tachypacing-induced canine failing heart.2002
- Author(s)
  Satoh S, Suematsu N, Ueda Y, Tsutsui H, Egashira K, Takeshita A, Makino N
- Journal Title
  
  J Cardiovasc Pharm 39(1)
  
  Pages: 88-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Long-term Inhibition of Nitric Oxide Synthesis Increases Arterial Thrombogenecity Through Angiotensin II-induced Expression of Tissue Factor and Resultant Production of Thrombin in Rats.2002
- Author(s)
  Kubo-Inoue M, Egashira K, Usui M, Takemoto M, Ohtani K, Katoh M, Shimokawa H, Takeshita A
- Journal Title
  
  Am J Physiol- Heart C 282(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Transforming Growth Factor-β Function Blocking Prevents Myocardial Fibrosis and Diastolic Dysfunction in Pressure-Overloaded Rats.2002
- Author(s)
  Kuwahara F, Kai H, Tokuda K, Kai M, Takeshita A, Egashira K, Imaizumi T
- Journal Title
  
  Circulation 106(1)
  
  Pages: 130-135
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Inhibits Restenotic Changes (Neointimal Hyperplasia) After Balloon Injury in Rats and Monkeys.2002
- Author(s)
  Usui M, Egashira K, Ohtani K, Kataoka C, Ishibashi M, Hiasa K, Katoh M, Zhao QW, Kitamoto S, Takeshita A
- Journal Title
  
  FASEB J 16
  
  Pages: 1838-1840
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036
[Journal Article] Essential Role of Monocyte Chemoattractant Protein-1 in the Development of Restenotic Changes (Neointimal Hyperplasia and Constrictive Remodeling) After Balloon Angioplasty in Hypercholesterolemic Rabbits.2002
- Author(s)
  Mori E, Komori K, Yamaoka T, Kataoka C, Takeshita A, Usui M, Egashira K, Sugimachi K
- Journal Title
  
  Circulation 105
  
  Pages: 2905-2910
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207036

1. SHIMOKAWA Hiroaki (00235681)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. IMAIZUMI Tsutomu (60148947)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
3. UENO Hikaru (50260378)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
4. SUEISHI Katsuo (70108710)

# of Collaborated Projects: 8 results

# of Collaborated Products: 2 results
5. SUNAGAWA Kenji (50163043)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
6. KANAIDE Hideo (80038851)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
7. TOMOIKE Hitonobu (90112333)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. ICHIKI Toshihiro (80311843)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
9. TSUTSUI Hiroyuki (70264017)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
10. NAKAMURA Motoomi (60037322)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
11. EGASHIRA Kensuke (60260379)

# of Collaborated Projects: 5 results

# of Collaborated Products: 59 results
12. KOYANAGI Samon (90128017)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
13. UTSUMI Hideo (20101694)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
14. INOU Tetsuji (10159965)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. MOHRI Masahiro (60264032)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. YASUI hisataka (20089923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. KOSHIISHI Ichiro (20170235)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. 門司晃 (00294942)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. KOBAYASHI Sei (80225515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKASHIMA Mikio (80159061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ITOU Takeo (70159888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SUZUKI Hikaru (80037548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KANNO Morio (00109422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAKAYAMA Kei-ichi (80291508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. NAGAI Ryozo (60207975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ITO masaaki (00223181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. KAIBUCHI Kozo (00169377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KOIKE George (90325522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. TAKESHITA Keizo (70175438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. YAMADA Ken-ichi (60346806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. KOGA Noboru (60161890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. HIRATA Hiroshi (60250958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
33. INOGUCHI Toyoshi (00294926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. AKAIKE Norio (30040182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 吉田恭子 (00242967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 池田康夫 (00110883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 大原郁一 (90185364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 渡辺武 (40028684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 丸岡雄二 (10190563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 平川洋次 (90332840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 小澤俊彦 (40160858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 市川和洋 (10271115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 多治見司 (40136461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 山元寅男 (80037324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 田川博章

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 市來俊弘

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 山本悦治

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. 北本史朗

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 臼井真

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 稲生哲二

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKESHITA Akira 竹下 彰

Research Projects

Research Products

Co-Researchers

アルギニンポリマーを用いたオリゴペプチドの細胞核内導入による血管病変の蛋白治療Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Rho/Rho-kinase-mediated pathway in the pathogenesls of atherosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

平滑筋細胞の分化増殖および血管病変形成におけるCREBの果たす役割に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOLECULAR MECHANISMS OF CARDIOVASCULAR REMODELING INDUCED BY CHRONIC INHIBITION OF NITRIC OXIDE SYNTHESIS : ROLE OF NF-κB AND MCP-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of intracellular therapy to induce a regression of coronary arteriosclerotic lesionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肥大心に特異的に発現する遺伝子のSubtraction法による単離とその機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

不全心における細胞骨格-細胞外マトリックスと細胞接着分子の役割に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

機械的ストレスによる心肥大形成の細胞・分子機構における細胞骨格の役割に関する研究Principal Investigator

TAKESHITA Akira 竹下彰