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YOSHIDA Hideo
吉田 秀夫
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Researcher Number
30116131
External Links
Affiliation
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2010 : The University of Tokushima, ヘルスバイオサイエンス研究部, 教授
2006 – 2010 : 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授
2009 : 徳島大, ヘルスバイオサイエンス研究部, 教授
2008 : 徳島大, 歯学部, 教授
2008 : 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授
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2005 : 徳島大, 助教授
2004 – 2005 : 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教授
2004 : 徳島大, 歯学部, 助教授
1996 – 2002 : 徳島大, 歯学部, 助教授
1986 – 2002 : 徳島大学, 歯学部, 助教授
Less
Review Section/Research Field
Principal Investigator
Surgical dentistry
/
外科・放射線系歯学
/
病態科学系歯学(含放射線系歯学)
/
Social dentistry
/
Surgical dentistry
Except Principal Investigator
Surgical dentistry
/
外科・放射線系歯学
/
病態科学系歯学(含放射線系歯学)
/
Surgical dentistry
Keywords
Principal Investigator
in situ hybridization / アポトーシス / HGF / TGF-β3 / Apoptosis / OK-432 / GFP / サイトケラチン / 姉妹染色分体交換 / secondary palatal shelves
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More
/ morphogenesis / ヒト唾液腺癌細胞 / HSV-tk / 形態形成 / ビメンチン / 二次口蓋突起 / 電気穿孔法 / Vimentin / luciferase / 抗腫瘍活性 / 転移腫瘍 / cAMP-dependent protein kinase (PKA) / dB-cAMP / 姉妹染色分体交換(SCE) / Dibotyryl cyclicAMP / ニューキノロン / clinical trial / Ras癌遺伝子産物 / 歯周病原細菌 / HGF-SF / EBベクター / プロテインキナーゼA / エトポシド / 癌免疫療法剤OK-432 / 上顎洞癌 / dendritic cell / gene-therapy / Cancer Immunotherapy / TS-1 / sister chromatid exchange cis-platinum / 細胞免疫療法 / PKR / 細胞増殖抑制 / 8-chloro-adensine / 口腔衛生学 / 專門的口腔ケア / Experimental chemotherapy / Toll-like receptor 4 (TLR4) / 単純ヘルペスチミジンキナーゼ / electroporation / ルシファラーゼ / EB-ウイルスベクター / 分化誘導剤 / シスブラチン / ras癌遺伝子産物 / 上皮間葉転換 / マイトマイシンC / epothelial-mesenchymal transform / c-Met oncogene / 頭剄部癌 / cell proliferation / 頭頸部癌 / 免疫細胞療法 / 抗癌剤TS-1 / dibutyryl cyclic AMP / 口蓋癒合 / 頬粘膜乾燥 / シスプラチン / 遺伝子治療 / ルシフェラーゼ / Dibutyryl cyclic AMP / 実験的化学療法 / 唾液IgA / epithelium-mesenchymal transform / 口腔粘膜癌 / lipoteichoic acid-related molecule OK-PSA / EB-vector / 細胞分化誘導 / リポタイコ酸関連分子OK-PSA / 臨床試験 / 染色体異常 / トポイソメラーゼII阻害剤 / palatal fusion / human adenocarcinoma cell line / SF / Head and neck cancer / Toll-like receptor 4 / 専門的口腔ケア / ras p21 / 唾液腺癌細胞 / c-Met癌遺伝子 / 樹状細胞 / 上皮-間葉転換 / リウマチ患者 / 口腔内不潔物 / 熱ショック蛋白質 / 上皮癒合 / ras癌遺伝子 / 自己免疫疾患 / Human salivary gland cancer / プロティンキナーゼA / cytodifferentiation / 8-chloro-aenosine 3' : 5'-monophosphate (8-Cl-cAMP) / cytokeratin / 上皮-間葉変換 / TGF-β / 舌苔 / c-AMP誘導体 / mitomycin C / 自己抗体 / Toll-loke receptor
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More
Except Principal Investigator
アポトーシス / ヒト唾液腺癌細胞 / 分化誘導 / DNA hypomethylation / 口腔癌 / 唾液腺癌細胞 / 分化因子 / Apoptosis / HPLC / TSC-22 / 唾液腺腺房細胞 / 細胞分化 / 末梢リンパ球亜群 / LAK細胞 / HSG cell line / Human salivary cancer cells / OK-432 / LAK cells / FdUMP / Oral cancer / 造腫瘍性ヒト唾液腺介在部導管上皮細胞 / 5-フルオロウラシル / deoxyribonucleosidetriphosphate / Hexamethylene bisacetamide / dibutyryl cAMP / cell cycle / 放射線 / 放射線治療 / TGF-β1 / p27^<Klp1> / 増殖・分化 / Cellular differentiation / Screening system / 個別化治療 / salivary gland cancer / Phenotype of cancer cells / 分化誘導療法 / Salivary adenoid squamous carcinoma-forming cells / 抹消リンパ球亜群 / p27^<Kipl> / apoptosis / 薬物受容体 / 8-chloroadenosine3':5'-cyclic monophosphate / Proteosome / 5-fluoro-2'-deoxyuridine / 口腔小唾液腺由来腺様扁平上皮癌細胞 / 口腔扁平皮癌 / Drug receptor / インタ-ロイキン2 / Hesamethylene bisacetamide / lipoteichoic acid / 高転移性唾液腺癌細胞 / Human salivary gland cancer cells / ベスナリノン / HSG ell ine / 唾液腺粘液嚢胞 / エトポシド / キラー活性 / oral squamous cell carcinoma / 唾液腺癌 / 唾液腺筋上皮細胞 / Anti-tumor agents / 唾液腺由来腺様扁平上皮癌細胞 / 不死化正常ヒト唾液腺細胞 / p27^<Kip1> / NK細胞 / head and neck cancer / サイトケラチン / NK cells / キラー細胞 / プロテイン・キナ-ゼC / 細胞分化誘導剤 / cellular differentiation / 癌細胞表現形質 / Killerリンパ球 / p21^<WAF> / Cytokeratin / p27^<kip1> / Therapy of Oral cancer / Plectin / プロテオソーム / 頭頸部癌 / 蛋白分解酵素 / インターロイキン2 / Local immunotherapy / 8-chloroadenosine 3':5'-cyclic monophosphate / Subsets of peripheral blood lymphocyte / 5-Fluorouracil / Human salivary gland duct cells / スクリーニングシステム / TGF-beta1 / 唾液腺上皮細胞 / vesnarinone / 8ーchloro odenosine 3':5'ーcyclic monophosphate / TLR / MMP-2 / 口腔扁平上皮癌 / グリア線維酸性蛋白 / ヌクレオチドプール / プロテイン・キナーゼA / プロテイン・キナーゼC / Subsets of peripheral blood lymphocytes / Hー7 / Cyst / 単クローン抗体 / p21^<Waf1> / 局所免疫療法 / Immune response / リポソーム / killer cells / Differentiation therapy / Killer リンパ球 / BRM / 分化誘導剤 / 抗癌剤 / p21^<waf1> / 癌免疫療法 / 口腔癌治療 / サイトカイン / 抗腫瘍効果 / リンパ球亜群 / 転写活性化能 / Killer lymphocyte / Cellular differentiation-inducing agents / ニューロフイラメント / radiation / 5-fluorouracil / 頭頚部癌 / 免疫応答 / 造腫瘍性ヒト腺房細胞癌細胞 / deoxyribonucleosidetriphesphete / プレクチン / cytokine / ADCC / killerリンパ球 / liposome / Protein kinase A / Protein kinase C / p21^<WAF1> / 8-chloroadenosine 3' : 5'-cyclic monophosphate / TGF-β / Radiotherapy / 高転移性ヒト唾液腺癌細胞 / Interleukin 2 / 分化因子遺伝子 / リポタイコ酸
Less
Research Projects
(
22
results)
Co-Researchers
(
19
People)
Project Start Year(Newest)
Project Start Year(Oldest)
The effect of professional oral health care on improving autoimmune disease
Principal Investigator
Principal Investigator
YOSHIDA Hideo
Project Period (FY)
2008 – 2010
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Social dentistry
Research Institution
The University of Tokushima
Comprehensive analysis of Toll-like receptor-related genes in oral cancer patients and development of individual cancer immunotherapy
Principal Investigator
OKAMOTO Masato
Project Period (FY)
2006 – 2008
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Surgical dentistry
Research Institution
Musashino University
Development of the therapy with an intratumoral administration of dendritic cells in combination with radiation or anti-cancer drugs against oral cancer : Application to clinical trial.
Principal Investigator
Principal Investigator
YOSHIDA Hideo
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Surgical dentistry
Research Institution
The University of Tokushima
The correlation between TGF-b3 and HGF/SF in the process of fusion of secondary palatal shelves
Principal Investigator
Principal Investigator
YOSHIDA Hideo
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
病態科学系歯学(含放射線系歯学)
Research Institution
University of Tokushima
The role of c-Met oncogene expression in the secondary palate shelves adhesion process.
Principal Investigator
Principal Investigator
YOSHIDA Hideo
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
病態科学系歯学(含放射線系歯学)
Research Institution
Tokushima University
Study on differentiation and apoptosis-inducing therapy for head and neck cancer by vesnarinone
Principal Investigator
SATO Mitsunobu
Project Period (FY)
1998 – 2001
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Surgical dentistry
Research Institution
The University of Tokushima
Lipoteichoic acid : Augmentation of the therapeutic effect of radiation and 5-fluorouracil in head and neck cancer
Principal Investigator
SATO Mitsunobu
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Surgical dentistry
Research Institution
The University of Tokushima
Development of a new method of gene therapy for head and neck cancer patients by electroporation of plasmid vector
Principal Investigator
Principal Investigator
YOSHIDA Hideo
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Surgical dentistry
Research Institution
The University of Tokushima
Influence of antineoplastic drug (5-fluorouracil) to the dNTP pool of a human salivary gland adenocarcinoma cell line (HSG)
Principal Investigator
NISHIDA Toshinobu
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
病態科学系歯学(含放射線系歯学)
Research Institution
The University of Tokushima
Effect of site selective cAMP & its metabolite on human adenocarucinoma cell line
Principal Investigator
Principal Investigator
YOSHIDA Hideo
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Surgical dentistry
Research Institution
University of Tokushima
Detection of Novel Drug Receptor and Mechanism of Induction of Differentiation and Apoptosis in Human Salivary Cancer Cells
Principal Investigator
SATO Mitsunobu
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Surgical dentistry
Research Institution
The University of Tokushima
Study for both the establishment of in vivo model system for the development of salivary mucous cyst and its treatment
Principal Investigator
AZUMA Masayuki
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Surgical dentistry
Research Institution
The University of Tokushima
Development of screening system for searching cellular differentiation-inducing agents by utlizing human salivary cancer cells
Principal Investigator
SATO Mitsunobu
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
病態科学系歯学(含放射線系歯学)
Research Institution
The University of Tokushima
ポイソメラーゼII阻害剤エトポシドによるヒト唾液腺癌細胞の分化誘導とアポトーシス
Principal Investigator
Principal Investigator
吉田 秀夫
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Surgical dentistry
Research Institution
The University of Tokushima
ニューキノロン剤のヒト培養細胞に及ぼす細胞遺伝学的影響
Principal Investigator
Principal Investigator
吉田 秀夫
Project Period (FY)
1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
外科・放射線系歯学
Research Institution
The University of Tokushima
Study of Differentiation Therapy for Salivary Gland Cancer
Principal Investigator
SATO Mitsunobu
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
外科・放射線系歯学
Research Institution
THE UNIVERSITY OF TOKUSHIMA
ヒト唾液腺癌細胞における筋上皮或いは腺房細胞に分化誘導する細胞性因子の産生と特性
Principal Investigator
SATO Mitsunobu
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokushima
ヒト唾液腺癌細胞における筋上皮或は腺房細胞に分化誘導する細胞性因子の産生と特性
Principal Investigator
佐藤 光信
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokushima
ras癌遺伝子p21の発現と構造異常からみた口腔粘膜癌での高転移症例の早期診断
Principal Investigator
Principal Investigator
吉田 秀夫
Project Period (FY)
1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
外科・放射線系歯学
Research Institution
The University of Tokushima
Local Immunotherapy of Oral Cancer with LAK Cells and Interleukin 2
Principal Investigator
SATO Mitsunobu
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
外科・放射線系歯学
Research Institution
The University of Tokushima
The experimental chemotherapy on human salivary gland cancer.
Principal Investigator
Principal Investigator
YOSHIDA Hideo
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
外科・放射線系歯学
Research Institution
Tokushima University
Immune Responses Associated with Killer-Lymphocyte Population in Oral Cancer and their Therapeutic Significance
Principal Investigator
SATO Mitsunobu
Project Period (FY)
1986 – 1989
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
外科・放射線系歯学
Research Institution
The University of Tokushima
# of Projects (Dsc)
# of Projects (Asc)
1.
SATO Mitsunobu
(00028763)
# of Collaborated Projects :
9results
# of Collaborated Products :
0results
2.
YURA Yoshiaki
(00136277)
# of Collaborated Projects :
6results
# of Collaborated Products :
0results
3.
YANAGAWA Tetsuo
(40136263)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
4.
AZUMA Masayuki
(20144983)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
5.
HARADA Koji
(60253217)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
6.
OKAMOTO Masato
(10243718)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
7.
KAWAMATA Hitoshi
(70224847)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
8.
洪 英満
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
9.
HINODE Daisuke
(70189801)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
10.
YOSHIOKA Masami
(90243708)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
11.
YOSHIDA Kaya
(60363157)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
12.
KAYAMA Shizuo
(50432761)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
13.
KAJI Ryoji
(30204390)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
14.
NISHIDA Toshinobu
(50156080)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
15.
IGA Hiroki
(40175188)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
16.
BANDO Takashi
(80208727)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
17.
TAKEGAWA Yoshihiro
(40035754)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
18.
上野 明道
(80136267)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
19.
林 良夫
(00127854)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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